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Panama City

$107+ Cheap flights from Illinois to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — PTY
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Illinois to Panama City

Keep the following information in mind while searching for Illinois to Panama City flight deals. Data was last updated September 16, 2025.

Round-trip from

$269
(Gotogate)

One-way from

$107
(Cheapflightsfares)

Popular in

December

Cheapest in

November

Average price

$548

Good round-trip deal

$404 or less

Good one-way deal

$165 or less
From Illinois to Panama City Tocumen Intl
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One-way flight from Illinois to Panama City Tocumen Intl
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Highest demand for flights based on searches. 3% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Illinois to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Illinois to Panama City Tocumen Intl.
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Find flight deals from Illinois to Panama City

Cheapest flights from Illinois to Panama City
Explore the most affordable flight options available from Illinois to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/232:35 pmORD - PTY
1 stop9h 35mAvianca
Wed 10/299:45 amPTY - ORD
1 stop11h 35mAvianca
Deal found 9/16$272
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/232:35 pmORD - PTY
1 stop9h 35mAvianca
Thu 10/309:45 amPTY - ORD
1 stop11h 35mAvianca
Deal found 9/15$275
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3011:20 pmORD - PTY
1 stop17h 35mAvianca
Sun 11/29:45 amPTY - ORD
1 stop11h 35mAvianca
Deal found 9/15$345
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3011:20 pmORD - PTY
1 stop14h 40mAvianca
Thu 11/69:45 amPTY - ORD
1 stop11h 35mAvianca
Deal found 9/15$349
This Gotogate deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3111:20 pmORD - PTY
1 stop14h 40mAvianca
Fri 11/79:45 amPTY - ORD
1 stop11h 35mAvianca
Deal found 9/16$350
This Avianca deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/110:54 amORD - PTY
2 stops13h 51mAvianca
Sat 10/185:25 pmPTY - ORD
1 stop19h 50mAvianca
Deal found 9/16$355
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/24:10 pmORD - PTY
1 stop17h 10mAvianca
Wed 12/109:45 amPTY - ORD
1 stop11h 35mAvianca
Deal found 9/15$357
This Avianca deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/610:20 pmORD - PTY
1 stop14h 40mAvianca
Mon 11/105:55 pmPTY - ORD
2 stops16h 34mAvianca
Deal found 9/15$360
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:00 amSTL - PTY
1 stop6h 56mDelta
Wed 10/222:21 pmPTY - STL
1 stop17h 44mDelta
Deal found 9/15$386
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:15 amSTL - PTY
1 stop7h 59mUnited Airlines
Tue 10/2110:00 amPTY - STL
1 stop12h 00mUnited Airlines
Deal found 9/15$393
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/138:25 amSTL - PTY
1 stop10h 12mUnited Airlines
Thu 10/233:30 pmPTY - STL
2 stops19h 19mUnited Airlines
Deal found 9/15$398
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/143:03 pmSTL - PTY
2 stops23h 00mAmerican Airlines
Thu 10/233:15 pmPTY - STL
2 stops18h 20mAmerican Airlines
Deal found 9/14$399

Cheapflights Fare Finder

 
Customize your flight search to find flights from Illinois to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Illinois to Panama City that are best for you.

Fly from

Illinois

Fly to

Panama City

Route

Depart

Return

Price

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Mon 10/13

6:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

Thu 10/23

2:21 pm-11:41 pm

1 stop9h 20m

$386

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Tue 10/14

6:15 am-2:14 pm

1 stop7h 59m

Panama City Tocumen Intl

Tue 10/21

10:00 am-10:00 pm

1 stop12h 00m

$393

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Thu 10/16

6:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Tue 10/21

10:00 am-10:00 pm

1 stop12h 00m

$393

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Mon 10/13

8:25 am-6:37 pm

1 stop10h 12m

Panama City Tocumen Intl

Tue 10/21

10:00 am-10:00 pm

1 stop12h 00m

$393

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Mon 10/13

8:25 am-6:37 pm

1 stop10h 12m

Panama City Tocumen Intl

Thu 10/23

3:30 pm-10:49 am

2 stops19h 19m

$398

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Thu 10/16

6:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Mon 10/20

3:30 pm-10:49 am

2 stops19h 19m

$398

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 10/15

6:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Tue 10/21

3:30 pm-10:49 am

2 stops19h 19m

$398

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Thu 10/16

6:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Thu 10/23

3:30 pm-10:49 am

2 stops19h 19m

$398

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 10/15

6:15 am-2:14 pm

1 stop7h 59m

Panama City Tocumen Intl

Wed 10/22

3:30 pm-10:49 am

2 stops19h 19m

$398

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Mon 10/13

8:25 am-6:37 pm

1 stop10h 12m

Panama City Tocumen Intl

Wed 10/22

3:30 pm-10:49 am

2 stops19h 19m

$398

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 52 results
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Best time to book a flight from Illinois to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Illinois with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Illinois to Panama City

What is the cheapest month to book a flight from Illinois to Panama City?

Currently, October is the cheapest month in which you can book a flight from Illinois to Panama City (average of $478). Flying from Illinois to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IL to PTY?

Find hourly flight availability from Illinois to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from Illinois to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Illinois to Panama City

Explore weekly flight availability from Illinois to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 16, 2025.

The most flights from USIL to PTY are scheduled on a Monday (5 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (3 on average).

Related info for your journey

Find useful and relevant information for your journey from Illinois to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Illinois?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Illinois to Panama City.

  • How long is the flight from Illinois to Panama City?

    Departing from Illinois to Panama City will take you 5h 28m. There are 2330 mi between Illinois and Panama City. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Illinois to Panama City one-way?

    One-way options have recently been found by users for as low as $108 on Avianca. Other airlines that offer cheap prices include Delta from $221 and American Airlines from $248 one-way.

  • What are the most popular routes from Illinois to Panama City?

    While some choose either Chicago Midway - Panama City Tocumen Intl or Evansville Dress Regional - Panama City Tocumen Intl, Chicago O'Hare Intl - Panama City Tocumen Intl is the most popular route from Illinois to Panama City.

  • What are the most reliable airlines from Illinois to Panama City?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Illinois to Panama City on time: EVA Air (89%), United Airlines (85%), Copa Airlines (76%).

  • What are the cheapest flights from Illinois to Panama City?

    The cheapest flight price from Illinois to Panama City is $133. On average you can expect to pay $700. The most popular route, (Chicago O'Hare Intl - Panama City Tocumen Intl), can usually be booked for $359.

  • Can I find deals for flights from Illinois to Panama City that include hotel bookings?

    Yes. In addition to deals on Illinois to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Illinois to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Illinois to Panama City.

  • Can I find deals for business class flights from Illinois to Panama City?

    Yes. Cheapflights offers flight deals from Illinois to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Illinois to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Illinois to Panama City (average of $478). Flying from Illinois to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Illinois to Panama City

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Top 5 airlines flying from Illinois to Panama City

Discover the top 5 airlines that operate flights from Illinois to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$334Average$457FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$464Average$583FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$478Average$653FlexibilityNo cancel feeOn-time69%
DeltaCheapest$479Average$653FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$563Average$707FlexibilityNo cancel feeOn-time71%

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