What are the cheapest airlines to fly from Illinois to Panama City one-way?

One-way options have recently been found by users for as low as $164 on United Airlines. Other airlines that offer cheap prices include American Airlines from $187 and Avianca from $194 one-way.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the most popular routes from Illinois to Panama City?

While some choose either Evansville Dress Regional - Panama City Tocumen Intl or Chicago Midway - Panama City Tocumen Intl, Chicago O'Hare Intl - Panama City Tocumen Intl is the most popular route from Illinois to Panama City.

What are the cheapest flights from Illinois to Panama City?

The cheapest flight price from Illinois to Panama City is $189. On average you can expect to pay $965. The most popular route, (Chicago O'Hare Intl - Panama City Tocumen Intl), can usually be booked for $451.

What are the most reliable airlines from Illinois to Panama City?

Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Illinois to Panama City on time: EVA Air (90%), United Airlines (88%), Copa Airlines (79%).

What are the most popular airlines that fly from Illinois to Panama City?

Before booking your flight from Illinois to Panama City check out the most popular airlines for this route: American Airlines, Avianca or Copa Airlines.

How far in advance should I book a flight from Illinois to Panama City?

Users have found that booking a flight from Illinois to Panama City at least 14 days early can save you up to 54% on average compared to booking a flight this week. If booking 14 days before your flight isn’t an option for you, users have found flights from Illinois to Panama City for as little as $464 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $759 for flights departing within the next 3 days.

What is the cheapest month to fly from Illinois to Panama City?

November can be a great time to fly to Panama City from Illinois with a flight ticket averaging about $580. Cheapflights users have found deals in the month of November for as cheap as $432. The most expensive prices can be found in the month of December.

What airport do you fly into for flights to Panama City from Illinois?

Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Illinois to Panama City.

Can I find deals for flights from Illinois to Panama City that include hotel bookings?

Yes. In addition to deals on Illinois to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Illinois to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Illinois to Panama City.

Can I find deals for business class flights from Illinois to Panama City?

Yes. Cheapflights offers flight deals from Illinois to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$194+ Flights from Illinois to Panama City

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Cheap flight deals from Illinois to Panama City

Round-trip from	$393 (American Airlines)
One-way from	$164 (United Airlines)
Popular in	December
Cheapest in	November
Average price	$525
Good round-trip deal	$463 or less
Good one-way deal	$208 or less

From Illinois to Panama City Tocumen Intl

Search Deals

One-way flight from Illinois to Panama City Tocumen Intl

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($46 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Price to beat on a round-trip flight from Illinois to Panama City Tocumen Intl.

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Price to beat on a one-way flight from Illinois to Panama City Tocumen Intl.

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Find flight deals from Illinois to Panama City

Cheapest flights from Illinois to Panama City
Explore the most affordable flight options available from Illinois to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Thu 11/66:00 amSTL - PTY

1 stop6h 56mDelta

Thu 11/133:17 pmPTY - STL

1 stop9h 22mDelta

Deal found 7/31

$393

Thu 11/66:15 amSTL - PTY

1 stop7h 30mUnited Airlines

Thu 11/134:41 pmPTY - STL

2 stops19h 10mUnited Airlines

Deal found 7/31

$398

Wed 9/35:28 amSTL - PTY

1 stop7h 27mAmerican Airlines

Sun 9/73:31 pmPTY - STL

2 stops20h 52mAmerican Airlines

Deal found 7/30

$420

Thu 10/232:35 pmORD - PTY

1 stop9h 35mAvianca

Sun 10/263:19 amPTY - ORD

1 stop9h 56mAvianca

Deal found 7/31

$446

Thu 10/23:07 pmORD - PTY

Nonstop5h 28mCopa Airlines

Sun 10/56:45 pmPTY - ORD

Nonstop5h 36mCopa Airlines

Deal found 7/31

$451

Thu 10/29:05 pmORD - PTY

1 stop17h 09mUnited Airlines

Sun 10/123:30 pmPTY - ORD

1 stop8h 44mUnited Airlines

Deal found 7/30

$456

Tue 9/305:05 amORD - PTY

2 stops16h 05mMultiple Airlines

Mon 10/63:25 amPTY - ORD

2 stops19h 23mMultiple Airlines

Deal found 7/30

$457

Wed 11/196:00 amMDW - PTY

1 stop6h 52mDelta

Sun 11/238:05 amPTY - MDW

1 stop14h 39mDelta

Deal found 7/30

$465

Thu 10/306:00 amEVV - PTY

1 stop6h 56mDelta

Wed 11/53:21 pmPTY - EVV

1 stop7h 32mDelta

Deal found 7/31

$467

Wed 9/38:29 pmORD - PTY

2 stops18h 02mAmerican Airlines

Wed 9/101:45 pmPTY - ORD

2 stops17h 39mAmerican Airlines

Deal found 7/30

$470

Thu 10/305:21 pmEVV - PTY

2 stops20h 39mAmerican Airlines

Wed 11/52:43 pmPTY - EVV

2 stops20h 53mAmerican Airlines

Deal found 7/31

$524

Sat 9/66:15 amMDW - PTY

1 stop13h 18mMultiple Airlines

Sat 9/139:25 amPTY - MDW

1 stop13h 52mMultiple Airlines

Deal found 7/31

$619

Best flights from Illinois to Panama City
Discover carefully curated flight deals from Illinois to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 31, 2025.

Wed 10/225:23 amSTL - PTY

1 stop8h 37mAmerican Airlines

Sun 10/263:15 pmPTY - STL

1 stop8h 41mAmerican Airlines

Deal found 7/30

$415

Wed 9/311:05 amSTL - PTY

1 stop7h 32mUnited Airlines

Sun 9/73:30 pmPTY - STL

1 stop27h 28mUnited Airlines

Deal found 7/30

$419

Thu 10/232:35 pmORD - PTY

1 stop9h 35mAvianca

Sat 10/253:19 amPTY - ORD

1 stop9h 56mAvianca

Deal found 7/29

$446

Thu 10/23:07 pmORD - PTY

Nonstop5h 28mCopa Airlines

Sun 10/56:45 pmPTY - ORD

Nonstop5h 36mCopa Airlines

Deal found 7/31

$451

Tue 9/305:05 amORD - PTY

2 stops16h 05mMultiple Airlines

Mon 10/63:25 amPTY - ORD

2 stops19h 23mMultiple Airlines

Deal found 7/30

$457

Wed 11/196:00 amMDW - PTY

1 stop6h 52mDelta

Sun 11/238:05 amPTY - MDW

1 stop14h 39mDelta

Deal found 7/30

$465

Thu 10/29:05 pmORD - PTY

1 stop17h 09mUnited Airlines

Sun 10/123:30 pmPTY - ORD

1 stop8h 44mUnited Airlines

Deal found 7/30

$456

Thu 10/306:00 amEVV - PTY

1 stop6h 56mDelta

Wed 11/53:21 pmPTY - EVV

1 stop7h 32mDelta

Deal found 7/31

$467

Wed 9/38:29 pmORD - PTY

2 stops18h 02mAmerican Airlines

Wed 9/101:45 pmPTY - ORD

2 stops17h 39mAmerican Airlines

Deal found 7/30

$470

Thu 10/305:21 pmEVV - PTY

2 stops20h 39mAmerican Airlines

Wed 11/52:43 pmPTY - EVV

2 stops20h 53mAmerican Airlines

Deal found 7/31

$524

Sat 9/66:15 amMDW - PTY

1 stop13h 18mMultiple Airlines

Sat 9/139:25 amPTY - MDW

1 stop13h 52mMultiple Airlines

Deal found 7/31

$619

Sun 9/1410:35 amSTL - PTY

1 stop9h 44mMultiple Airlines

Sat 9/203:20 amPTY - STL

2 stops33h 42mMultiple Airlines

Deal found 7/31

$824

Last-minute flights from Illinois to Panama City
Discover last-minute flight deals from Illinois to Panama City. Data last updated July 31, 2025 and is based on user searches.

Fri 8/14:31 pmEVV - PTY

2 stops21h 44mAmerican Airlines

Wed 8/63:30 pmPTY - EVV

2 stops19h 02mAmerican Airlines

Deal found 7/31

$672

Fri 8/17:19 pmEVV - PTY

1 stop15h 15mMultiple Airlines

Wed 8/69:28 pmPTY - EVV

2 stops45h 11mMultiple Airlines

Deal found 7/31

$1,135

Sat 8/26:20 amMDW - PTY

1 stop13h 13mMultiple Airlines

Sat 8/93:20 amPTY - MDW

2 stops19h 04mMultiple Airlines

Deal found 7/30

$962

Tue 8/55:48 pmEVV - PTY

2 stops20h 42mAmerican Airlines

Sun 8/103:30 pmPTY - EVV

2 stops19h 58mAmerican Airlines

Deal found 7/31

$729

Tue 8/56:20 amEVV - PTY

1 stop6h 53mDelta

Sun 8/102:28 pmPTY - EVV

1 stop7h 24mDelta

Deal found 7/31

$1,726

Thu 8/78:09 amORD - PTY

2 stops28h 26mMultiple Airlines

Mon 8/1110:05 pmPTY - ORD

2 stops18h 06mMultiple Airlines

Deal found 7/29

$602

Thu 8/75:25 pmORD - PTY

1 stop17h 00mAvianca

Mon 8/118:10 pmPTY - ORD

1 stop19h 55mAvianca

Deal found 7/31

$662

Sat 8/98:25 amSTL - PTY

1 stop10h 12mUnited Airlines

Sat 8/233:30 pmPTY - STL

1 stop18h 31mUnited Airlines

Deal found 7/30

$630

Sat 8/94:32 pmSTL - PTY

2 stops21h 58mAmerican Airlines

Sat 8/233:30 pmPTY - STL

1 stop8h 29mAmerican Airlines

Deal found 7/29

$635

Sat 8/93:07 pmORD - PTY

Nonstop5h 28mCopa Airlines

Mon 8/116:45 pmPTY - ORD

Nonstop5h 36mCopa Airlines

Deal found 7/31

$989

Sat 8/2310:27 amORD - PTY

2 stops26h 08mMultiple Airlines

Sat 8/305:25 pmPTY - ORD

2 stops15h 57mMultiple Airlines

Deal found 7/30

$491

Wed 8/2710:35 amORD - PTY

1 stop8h 02mUnited Airlines

Wed 9/33:30 pmPTY - ORD

1 stop17h 54mUnited Airlines

Deal found 7/30

$465

One-way flights from Illinois to Panama City
Search for one-way flight options from Illinois to Panama City. Find affordable one-way fares based on user searches. Data last updated July 31, 2025.

Wed 9/172:35 pmORD - PTY

1 stop10h 10mAvianca

Deal found 7/30

$194

Sat 8/308:12 pmORD - PTY

2 stops24h 58mMultiple Airlines

Deal found 7/30

$203

Tue 10/286:00 amEVV - PTY

1 stop6h 56mDelta

Deal found 7/31

$221

Tue 10/285:54 pmEVV - PTY

2 stops20h 06mAmerican Airlines

Deal found 7/31

$247

Thu 10/305:56 pmMDW - PTY

2 stops20h 04mMultiple Airlines

Deal found 7/31

$305

Sat 10/185:20 amORD - PTY

2 stops8h 40mAmerican Airlines

Deal found 7/30

$351

Mon 12/299:23 pmORD - PTY

1 stop18h 44mUnited Airlines

Deal found 7/30

$489

Wed 9/36:00 amMDW - PTY

1 stop6h 50mDelta

Deal found 7/30

$689

Thu 12/1810:35 amMDW - PTY

2 stops45h 45mWestJet

Deal found 7/30

$2,658

Cheapflights Fare Finder

Use the filters below to find and compare flights from Illinois to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 10/22

5:23 am-2:00 pm

1 stop8h 37m

Panama City Tocumen Intl

Sun 10/26

3:15 pm-11:56 pm

1 stop8h 41m

$415

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 9/3

11:05 am-6:37 pm

1 stop7h 32m

Panama City Tocumen Intl

Sun 9/7

3:30 pm-6:58 pm

1 stop27h 28m

$419

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/23

2:35 pm-12:10 am

1 stop9h 35m

Panama City Tocumen Intl

Sat 10/25

3:19 am-1:15 pm

1 stop9h 56m

$446

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/2

3:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Sun 10/5

6:45 pm-12:21 am

Nonstop5h 36m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/2

9:05 pm-2:14 pm

1 stop17h 09m

Panama City Tocumen Intl

Sun 10/12

3:30 pm-12:14 am

1 stop8h 44m

$456

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Tue 9/30

5:05 am-9:10 pm

2 stops16h 05m

Panama City Tocumen Intl

Mon 10/6

3:25 am-10:48 pm

2 stops19h 23m

$457

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 11/19

6:00 am-1:52 pm

1 stop6h 52m

Panama City Tocumen Intl

Sun 11/23

8:05 am-9:44 pm

1 stop14h 39m

$465

EvansvillePanama City

EVV - PTY

EVVPTY

Evansville Dress Regional

Thu 10/30

6:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

Wed 11/5

3:21 pm-9:53 pm

1 stop7h 32m

$467

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 9/3

8:29 pm-2:31 pm

2 stops18h 02m

Panama City Tocumen Intl

Wed 9/10

1:45 pm-7:24 am

2 stops17h 39m

$470

EvansvillePanama City

EVV - PTY

EVVPTY

Evansville Dress Regional

Thu 10/30

5:21 pm-2:00 pm

2 stops20h 39m

Panama City Tocumen Intl

Wed 11/5

2:43 pm-10:36 am

2 stops20h 53m

$524

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 21 results

Best time to book a flight from Illinois to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Illinois with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Illinois to Panama City

What is the cheapest month to book a flight from Illinois to Panama City?

Currently, October is the cheapest month in which you can book a flight from Illinois to Panama City (average of $478). Flying from Illinois to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IL to PTY?

When flying from Illinois to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Delta, Copa Airlines, and United Airlines from Illinois to Panama City to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,981 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Copa Airlines

7.5

Good

1,493 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,900 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

WestJet

7.2

Good

2,978 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly into for flights to Panama City from Illinois?
Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Illinois to Panama City.
What are the cheapest airlines to fly from Illinois to Panama City one-way?
One-way options have recently been found by users for as low as $164 on United Airlines. Other airlines that offer cheap prices include American Airlines from $187 and Avianca from $194 one-way.
What are the most popular routes from Illinois to Panama City?
While some choose either Evansville Dress Regional - Panama City Tocumen Intl or Chicago Midway - Panama City Tocumen Intl, Chicago O'Hare Intl - Panama City Tocumen Intl is the most popular route from Illinois to Panama City.
What are the most reliable airlines from Illinois to Panama City?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Illinois to Panama City on time: EVA Air (90%), United Airlines (88%), Copa Airlines (79%).
What are the cheapest flights from Illinois to Panama City?
The cheapest flight price from Illinois to Panama City is $189. On average you can expect to pay $965. The most popular route, (Chicago O'Hare Intl - Panama City Tocumen Intl), can usually be booked for $451.
Can I find deals for flights from Illinois to Panama City that include hotel bookings?
Yes. In addition to deals on Illinois to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Illinois to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Illinois to Panama City.
Can I find deals for business class flights from Illinois to Panama City?
Yes. Cheapflights offers flight deals from Illinois to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Illinois to Panama City?
Currently, October is the cheapest month in which you can book a flight from Illinois to Panama City (average of $478). Flying from Illinois to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Illinois to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Avianca	Cheapest$339	Average$455	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$464	Average$586	FlexibilityNo cancel fee	On-time70%
American Airlines	Cheapest$478	Average$708	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$478	Average$650	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$478	Average$653	FlexibilityNo cancel fee	On-time69%

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$194+ Cheap flights from Illinois to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Illinois to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Illinois to Panama City

Keep the following information in mind while searching for Illinois to Panama City flight deals. Data was last updated July 31, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Illinois to Panama City

Cheapest flights from Illinois to Panama CityExplore the most affordable flight options available from Illinois to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Explore the most affordable flight options available from Illinois to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Illinois to Panama City that are best for you.

Best time to book a flight from Illinois to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Illinois with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Illinois to Panama City

What is the cheapest month to book a flight from Illinois to Panama City?

What is the cheapest time of day to fly from IL to PTY?

Find hourly flight availability from Illinois to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Delta, Copa Airlines, and United Airlines from Illinois to Panama City to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Illinois to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Panama City from Illinois?

What are the cheapest airlines to fly from Illinois to Panama City one-way?

What are the most popular routes from Illinois to Panama City?

What are the most reliable airlines from Illinois to Panama City?

What are the cheapest flights from Illinois to Panama City?

Can I find deals for flights from Illinois to Panama City that include hotel bookings?

How can I find direct flights from Illinois to Panama City?

Can I find deals for business class flights from Illinois to Panama City?

What is the cheapest month to book a flight from Illinois to Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Illinois to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Illinois to Panama City

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Travel Smart

Cheapest flights from Illinois to Panama City
Explore the most affordable flight options available from Illinois to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.