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Panama City

$193+ Cheap flights from Illinois to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/30. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — PTY
dic. 3 — dic. 101
mié. 12/3
mié. 12/10
1 adult, Economy
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Find flight deals from Illinois to Panama City

Cheapest flights from Illinois to Panama City
Explore the most affordable flight options available from Illinois to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 3, 2025.

This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/16:43 pmSTL - PTY
2 stops19h 02mUnited Airlines
vie. 12/54:41 pmPTY - STL
2 stops20h 34mUnited Airlines
Deal found 11/1$415
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/305:15 amSTL - PTY
1 stop7h 28mAmerican Airlines
dom. 12/74:43 pmPTY - STL
2 stops20h 49mAmerican Airlines
Deal found 11/2$437
This Copa Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/12:07 pmORD - PTY
Nonstop5h 28mCopa Airlines
jue. 12/47:20 pmPTY - ORD
Nonstop5h 45mCopa Airlines
Deal found 11/2$451
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/1510:20 pmORD - PTY
1 stop17h 35mMultiple Airlines
mar. 11/1811:25 amPTY - ORD
2 stops14h 02mMultiple Airlines
Deal found 11/1$454
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/108:02 pmORD - PTY
1 stop17h 10mDelta
dom. 11/168:05 amPTY - ORD
1 stop9h 41mDelta
Deal found 11/3$455
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/162:40 pmORD - PTY
1 stop24h 02mAmerican Airlines
mar. 12/234:55 pmPTY - ORD
1 stop18h 58mAmerican Airlines
Deal found 11/1$464
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/2910:47 amMDW - PTY
1 stop8h 12mDelta
mié. 12/33:46 pmPTY - MDW
1 stop9h 01mDelta
Deal found 11/3$466
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/57:33 amORD - PTY
Nonstop5h 27mCopa Airlines
sáb. 12/137:20 pmPTY - ORD
Nonstop5h 45mCopa Airlines
Deal found 11/3$466
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/59:34 amMDW - PTY
2 stops9h 25mDelta
mié. 12/103:46 pmPTY - MDW
1 stop9h 01mDelta
Deal found 11/3$470
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/56:45 amORD - PTY
2 stops12h 14mDelta
sáb. 12/138:05 amPTY - ORD
1 stop8h 15mDelta
Deal found 11/3$470
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/110:20 pmORD - PTY
1 stop14h 40mMultiple Airlines
jue. 12/47:50 pmPTY - ORD
2 stops23h 46mMultiple Airlines
Deal found 11/2$474
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/98:55 pmORD - PTY
2 stops15h 52mAmerican Airlines
dom. 12/144:43 pmPTY - ORD
2 stops15h 36mAmerican Airlines
Deal found 11/2$475

Cheap flight deals from Illinois to Panama City

Keep the following information in mind while searching for Illinois to Panama City flight deals. Data was last updated noviembre 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$394
(United Airlines)

One-way from

$193
(Cheapflightsfares)

Popular in

October

Cheapest in

November

Average price

$465

Good round-trip deal

$463 or less

Good one-way deal

$170 or less
Provider with most accurate pricing for Chicago (CHI)-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Panama City Tocumen Intl flights.
Search Deals
From Illinois to Panama City Tocumen Intl
Search Deals
One-way flight from Illinois to Panama City Tocumen Intl
Search Deals
High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Illinois to Panama City Tocumen Intl.
Search Deals
Price to beat on a one-way flight from Illinois to Panama City Tocumen Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Illinois to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 3, 2025.
Use the filters below to find and compare flights from Illinois to Panama City that are best for you.

Fly from

Illinois

Fly to

Panama City

Route

Depart

Return

Price

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

mar. 2/17

10:10 am-7:38 pm

1 stop8h 28m

Panama City Tocumen Intl

mié. 2/25

11:35 am-10:14 pm

1 stop11h 39m

$394

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

mar. 2/3

6:00 am-2:45 pm

1 stop7h 45m

Panama City Tocumen Intl

jue. 2/12

8:55 am-10:14 pm

1 stop14h 19m

$394

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

lun. 1/19

3:30 pm-1:27 pm

2 stops20h 57m

Panama City Tocumen Intl

vie. 1/23

4:50 pm-11:03 am

2 stops19h 13m

$398

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

vie. 1/23

6:00 am-7:38 pm

1 stop12h 38m

Panama City Tocumen Intl

mar. 1/27

4:41 pm-9:22 am

1 stop17h 41m

$411

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

vie. 4/10

4:32 pm-12:15 pm

2 stops19h 43m

Panama City Tocumen Intl

vie. 4/17

1:55 pm-9:25 am

2 stops19h 30m

$415

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

mar. 2/10

11:55 am-1:27 pm

2 stops24h 32m

Panama City Tocumen Intl

sáb. 2/14

4:04 pm-12:27 pm

2 stops21h 23m

$415

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

mar. 2/10

6:40 pm-5:07 pm

2 stops21h 27m

Panama City Tocumen Intl

sáb. 2/14

4:41 pm-9:23 am

1 stop17h 42m

$415

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

jue. 1/15

2:13 pm-8:35 pm

Nonstop5h 22m

Panama City Tocumen Intl

dom. 1/18

7:40 pm-12:24 am

Nonstop5h 44m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

sáb. 1/17

11:51 pm-6:13 am

Nonstop5h 22m

Panama City Tocumen Intl

sáb. 1/24

7:40 pm-12:24 am

Nonstop5h 44m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

sáb. 11/29

2:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

mié. 12/3

7:20 pm-12:05 am

Nonstop5h 45m

$451

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/1

Showing 1-10 of 46 results
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Best time to book a flight from Illinois to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Illinois with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Illinois to Panama City

What is the cheapest month to book a flight from Illinois to Panama City?

Currently, March is the cheapest month in which you can book a flight from Illinois to Panama City (average of $398). Flying from Illinois to Panama City in April is currently the most expensive (average of $464). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IL to PTY?

Find hourly flight availability from Illinois to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 3, 2025.

A simple way to save on the total cost of your ticket is to fly from Illinois to Panama City in the afternoon. If you’re flexible enough to do this you can expect to save up to 20% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Illinois to Panama City?

Use this chart to determine the cheapest time to fly round-trip from Illinois to Panama City. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Illinois to Panama City flight should consider departing on Saturday mornings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Illinois to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Illinois?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Illinois to Panama City.

  • How long is the flight from Illinois to Panama City?

    Departing from Illinois to Panama City will take you 5h 22m. There are 2330 mi between Illinois and Panama City. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Illinois to Panama City?

    While some choose either Chicago Midway - Panama City Tocumen Intl or Lambert-St Louis - Panama City Tocumen Intl, Chicago O'Hare Intl - Panama City Tocumen Intl is the most popular route from Illinois to Panama City.

  • What are the most reliable airlines from Illinois to Panama City?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Illinois to Panama City on time: Copa Airlines (92%), United Airlines (92%), EVA Air (90%).

  • What are the cheapest flights from Illinois to Panama City?

    The cheapest flight price from Illinois to Panama City is $133. On average you can expect to pay $789. The most popular route, (Chicago O'Hare Intl - Panama City Tocumen Intl), can usually be booked for $451.

  • Can I find deals for flights from Illinois to Panama City that include hotel bookings?

    Yes. In addition to deals on Illinois to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Illinois to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Illinois to Panama City.

  • Can I find deals for business class flights from Illinois to Panama City?

    Yes. Cheapflights offers flight deals from Illinois to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Illinois to Panama City?

    Currently, March is the cheapest month in which you can book a flight from Illinois to Panama City (average of $398). Flying from Illinois to Panama City in April is currently the most expensive (average of $464). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Illinois to Panama City

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Top 5 airlines flying from Illinois to Panama City

Discover the top 5 airlines that operate flights from Illinois to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$334Average$457FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$464Average$577FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$479Average$653FlexibilityNo cancel feeOn-time69%
DeltaCheapest$479Average$658FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$589Average$737FlexibilityNo cancel feeOn-time71%

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