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Panama City

$256+ Cheap flights from Detroit (DTT) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/19. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — PTY
May 24 — May 311
Sun 5/24
Sun 5/31
1 adult, Economy
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Cheap flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.

This Mytrip deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
DTW
-
PTY
2 stops28h 15m
Multiple Airlines
Sun 5/314:25 am
PTY
-
DTW
3 stops26h 27m
Multiple Airlines
Deal found 4/20$499
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:30 am
DTW
-
PTY
3 stops19h 05m
Multiple Airlines
Wed 5/204:25 am
PTY
-
DTW
2 stops18h 28m
Multiple Airlines
Deal found 4/22$526
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
DTW
-
PTY
2 stops28h 15m
Multiple Airlines
Sun 5/174:25 am
PTY
-
DTW
3 stops26h 27m
Multiple Airlines
Deal found 4/21$540
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
DTW
-
PTY
2 stops28h 15m
Multiple Airlines
Tue 5/265:55 pm
PTY
-
DTW
2 stops28h 58m
Multiple Airlines
Deal found 4/21$576
This FlightHub deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:30 pm
DTW
-
PTY
2 stops18h 00m
Multiple Airlines
Tue 9/293:50 pm
PTY
-
DTW
2 stops23h 42m
Multiple Airlines
Deal found 4/20$609

Find flight deals from Detroit to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$499
(Mytrip)

One-way from

$256
(Kiwi.com)

Popular in

April

Cheapest in

January

Average price

$1,299
Provider with most accurate pricing for Detroit (DTT)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Panama City Tocumen Intl flights.
Search Deals
From Detroit (DTT) to Panama City Tocumen Intl
Search Deals
One-way flight from Detroit (DTT) to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($197 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($43 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Detroit to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 8/5

5:20 am-1:05 pm

1 stop8h 45m

Panama City Tocumen Intl

Wed 8/12

2:28 pm-11:40 pm

1 stop8h 12m

$733
Quickest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/16

6:30 am-12:56 pm

1 stop7h 26m

Panama City Tocumen Intl

Wed 9/30

2:21 pm-11:40 pm

1 stop8h 19m

$733

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/16

6:15 am-2:14 pm

1 stop8h 59m

Panama City Tocumen Intl

Wed 9/30

3:30 pm-9:50 am

2 stops17h 20m

$737

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 9/15

5:50 am-6:37 pm

2 stops13h 47m

Panama City Tocumen Intl

Tue 9/29

10:00 am-10:30 pm

1 stop11h 30m

$737

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 9/19

7:32 am-6:37 pm

2 stops12h 05m

Panama City Tocumen Intl

Sat 9/26

9:45 am-8:37 pm

1 stop9h 52m

$790

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 10/17

5:45 am-6:37 pm

2 stops13h 52m

Panama City Tocumen Intl

Sat 11/7

10:00 am-7:38 pm

1 stop9h 38m

$790

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 6/16

6:15 am-4:12 pm

1 stop10h 57m

Panama City Tocumen Intl

Tue 6/30

9:45 am-8:13 pm

1 stop9h 28m

$792

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 6/16

6:15 am-6:37 pm

1 stop13h 22m

Panama City Tocumen Intl

Sun 6/28

10:55 pm-9:31 am

1 stop9h 36m

$819
Cheapest one-way

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 6/19

6:10 am-8:30 am

2 stops27h 20m

$256

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 6/18

2:02 pm-7:20 pm

2 stops30h 18m

$262

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Showing 1-10 of 14 resultsSorted by cheapest first
1
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Compare providers for flights from Detroit to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Panama City

What is the cheapest month to book a flight from Detroit to Panama City?

Currently, March is the cheapest month in which you can book a flight from Detroit to Panama City (average of $514). Flying from Detroit to Panama City in November is currently the most expensive (average of $668). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Detroit to Panama City?

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Detroit to Panama City?

    Airlines like Delta and United Airlines fly from Detroit to Panama City in about 8h 45m. The time it takes to get you to your destination can typically vary by up to 14m. Airlines will cover a distance of 2302 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Detroit to Panama City round-trip?

    Flying on Copa Airlines is currently your cheapest option to Panama City, with prices starting at $611. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $628 and $629, respectively. Copa Airlines is currently priced 29% below the average price you’ll pay for this route.

  • Can I find deals for flights from Detroit to Panama City that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

  • Can I find deals for business class flights from Detroit to Panama City?

    Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to Panama City?

    Currently, March is the cheapest month in which you can book a flight from Detroit to Panama City (average of $514). Flying from Detroit to Panama City in November is currently the most expensive (average of $668). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Detroit to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Panama City flights
Detroit to Panama City flights
Midway to Panama City flights

Top 4 airlines flying from Detroit to Panama City

Discover the top 4 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$611Average$801FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$628Average$821FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$629Average$811FlexibilityNo cancel feeOn-time69%
DeltaCheapest$668Average$907FlexibilityNo cancel feeOn-timeN/A

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