Panama City

$287+ Cheap flights from Detroit (DTT) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — PTY
Jun 23 — Jun 301
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Detroit to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 24, 2026.

This FlightHub deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 pm
DTW
-
PTY
2 stops18h 00m
Multiple Airlines
Sun 10/43:50 pm
PTY
-
DTW
2 stops23h 42m
Multiple Airlines
Deal found 5/19$603
This FlightHub deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:30 pm
DTW
-
PTY
2 stops18h 00m
Multiple Airlines
Tue 9/293:50 pm
PTY
-
DTW
2 stops23h 42m
Multiple Airlines
Deal found 5/24$609
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/139:12 am
DTW
-
PTY
1 stop12h 07m
Multiple Airlines
Wed 7/225:55 pm
PTY
-
DTW
2 stops42h 00m
Multiple Airlines
Deal found 5/19$618
This Travelocity deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:30 pm
DTW
-
PTY
3 stops22h 25m
Multiple Airlines
Sun 9/273:50 pm
PTY
-
DTW
2 stops23h 42m
Multiple Airlines
Deal found 5/19$634
This Expedia deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:00 am
DTW
-
PTY
2 stops29h 30m
Multiple Airlines
Thu 8/203:50 pm
PTY
-
DTW
2 stops31h 08m
Multiple Airlines
Deal found 5/23$644
This Expedia deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
DTW
-
PTY
2 stops29h 30m
Multiple Airlines
Fri 8/283:50 pm
PTY
-
DTW
2 stops31h 08m
Multiple Airlines
Deal found 5/23$655
This FlightHub deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:30 pm
DTW
-
PTY
2 stops18h 00m
Multiple Airlines
Sun 10/183:50 pm
PTY
-
DTW
2 stops23h 42m
Multiple Airlines
Deal found 5/23$665
This Justfly.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am
DTW
-
PTY
2 stops29h 30m
Multiple Airlines
Sat 10/313:50 pm
PTY
-
DTW
2 stops24h 00m
Multiple Airlines
Deal found 5/21$673
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:12 am
DTW
-
PTY
1 stop12h 07m
Multiple Airlines
Mon 8/39:33 pm
PTY
-
DTW
2 stops20h 16m
Multiple Airlines
Deal found 5/19$677
This Orbitz deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:30 pm
DTW
-
PTY
3 stops22h 25m
Multiple Airlines
Mon 10/123:50 pm
PTY
-
DTW
2 stops23h 42m
Multiple Airlines
Deal found 5/20$690

Find flight deals from Detroit to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$603
(FlightHub)

One-way from

$287
(FlightHub)

Popular in

April

Cheapest in

January

Average price

$844
Provider with most accurate pricing for Detroit (DTT)-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for Detroit (DTT)-Panama City Tocumen Intl flights.
From Detroit (DTT) to Panama City Tocumen Intl
One-way flight from Detroit (DTT) to Panama City Tocumen Intl
Highest demand for flights based on searches. 16% potential increase in price ($176 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($46 potential savings vs. average RT price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
Use the filters below to find and compare flights from Detroit to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/30

5:30 pm-10:30 am

2 stops18h 00m

Panama City Tocumen Intl

Sun 10/4

3:50 pm-4:32 pm

2 stops23h 42m

$609

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/16

5:20 am-12:56 pm

1 stop8h 36m

Panama City Tocumen Intl

Wed 9/30

2:21 pm-12:54 am

1 stop9h 33m

$753

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/16

6:15 am-6:37 pm

1 stop13h 22m

Panama City Tocumen Intl

Wed 9/30

3:30 pm-11:24 am

2 stops18h 54m

$757

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 9/15

7:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Tue 9/29

3:30 pm-9:34 am

2 stops17h 04m

$757

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 10/9

7:10 pm-7:31 pm

1 stop25h 21m

Panama City Tocumen Intl

Sun 10/18

3:30 pm-10:30 pm

1 stop30h 00m

$787
Quickest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 10/9

5:20 am-12:56 pm

1 stop8h 36m

Panama City Tocumen Intl

Sun 10/18

2:21 pm-11:47 pm

1 stop8h 26m

$806

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 7/23

6:15 am-6:37 pm

1 stop13h 22m

Panama City Tocumen Intl

Fri 7/31

7:55 am-11:44 pm

1 stop14h 49m

$829
Cheapest one-way

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 10/6

5:30 pm-10:30 am

2 stops18h 00m

$287

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 10/28

4:45 pm-10:30 am

2 stops18h 45m

$290

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sun 11/1

4:45 pm-2:55 pm

3 stops22h 10m

$369

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/19

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Compare providers for flights from Detroit to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Panama City

What is the cheapest month to book a flight from Detroit to Panama City?

Currently, March is the cheapest month in which you can book a flight from Detroit to Panama City (average of $514). Flying from Detroit to Panama City in August is currently the most expensive (average of $692). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Detroit to Panama City?

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Detroit to Panama City?

    Airlines like Delta and United Airlines fly from Detroit to Panama City in about 8h 36m. The time it takes to get you to your destination can typically vary by up to 4h 46m. Airlines will cover a distance of 2302 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Detroit to Panama City round-trip?

    Flying on Copa Airlines is currently your cheapest option to Panama City, with prices starting at $611. Additional round-trip tickets that might be worth considering are offered by Delta and American Airlines, with the lowest prices starting at $668 and $673, respectively. Copa Airlines is currently priced 31% below the average price you’ll pay for this route.

  • Can I find deals for flights from Detroit to Panama City that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

  • Can I find deals for business class flights from Detroit to Panama City?

    Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to Panama City?

    Currently, March is the cheapest month in which you can book a flight from Detroit to Panama City (average of $514). Flying from Detroit to Panama City in August is currently the most expensive (average of $692). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Detroit to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Detroit to Panama City

Discover the top 4 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$611Average$934FlexibilityNo cancel feeOn-time70%
DeltaCheapest$668Average$931FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$673Average$821FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$708Average$839FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.