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Panama City

$265+ Cheap flights from Detroit (DTT) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — PTY
May 10 — May 171
Sun 5/10
Sun 5/17
1 adult, Economy
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Cheap flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.

This Mytrip deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:50 pm
DTW
-
PTY
2 stops32h 45m
Multiple Airlines
Tue 4/145:55 pm
PTY
-
DTW
2 stops29h 04m
Multiple Airlines
Deal found 4/6$534
This Mytrip deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:18 pm
DTW
-
PTY
2 stops29h 17m
Multiple Airlines
Sat 5/24:25 am
PTY
-
DTW
3 stops26h 37m
Multiple Airlines
Deal found 4/4$554
This Mytrip deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:50 am
DTW
-
PTY
3 stops35h 10m
Multiple Airlines
Tue 5/54:25 am
PTY
-
DTW
3 stops26h 27m
Multiple Airlines
Deal found 4/8$559
This Mytrip deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:25 am
DTW
-
PTY
3 stops30h 50m
Multiple Airlines
Wed 4/293:10 pm
PTY
-
DTW
3 stops26h 52m
Multiple Airlines
Deal found 4/6$569
This Mytrip deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:25 am
DTW
-
PTY
3 stops41h 10m
Multiple Airlines
Sat 5/25:30 am
PTY
-
DTW
3 stops16h 22m
Multiple Airlines
Deal found 4/8$581
This Mytrip deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:11 pm
DTW
-
PTY
3 stops45h 04m
Multiple Airlines
Thu 5/2810:10 am
PTY
-
DTW
3 stops35h 30m
Multiple Airlines
Deal found 4/6$592
This Mytrip deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:50 am
DTW
-
PTY
3 stops42h 45m
Multiple Airlines
Thu 4/234:25 am
PTY
-
DTW
3 stops15h 40m
Multiple Airlines
Deal found 4/7$598

Find flight deals from Detroit to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$554
(Mytrip)

One-way from

$265
(Kiwi.com)

Popular in

April

Cheapest in

January

Average price

$1,343
Provider with most accurate pricing for Detroit (DTT)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Panama City Tocumen Intl flights.
Search Deals
From Detroit (DTT) to Panama City Tocumen Intl
Search Deals
One-way flight from Detroit (DTT) to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($187 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($48 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Detroit to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sun 4/26

9:16 am-12:35 am

2 stops16h 19m

Panama City Tocumen Intl

Sat 5/2

10:26 am-11:06 am

1 stop23h 40m

$635

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 6/16

6:15 am-4:12 pm

1 stop10h 57m

Panama City Tocumen Intl

Tue 6/30

10:00 am-11:58 pm

2 stops12h 58m

$735

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 6/16

6:15 am-2:14 pm

1 stop8h 59m

Panama City Tocumen Intl

Sun 6/28

7:55 am-10:24 pm

1 stop13h 29m

$780

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 4/20

6:50 am-8:34 pm

1 stop14h 44m

Panama City Tocumen Intl

Mon 5/4

5:55 pm-11:53 pm

2 stops28h 58m

$792

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 5/19

9:00 am-6:37 pm

1 stop10h 37m

Panama City Tocumen Intl

Thu 5/28

10:00 am-11:43 pm

2 stops12h 43m

$800
Quickest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 4/29

9:00 am-6:37 pm

2 stops10h 37m

Panama City Tocumen Intl

Tue 5/19

9:45 am-8:43 pm

1 stop9h 58m

$829

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 6/1

6:10 am-10:30 am

2 stops29h 20m

Panama City Tocumen Intl

Sat 6/6

3:50 pm-11:59 pm

2 stops31h 09m

$843
Cheapest one-way

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 4/18

6:50 am-9:15 am

3 stops27h 25m

$271

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 5/22

12:55 pm-2:15 pm

3 stops26h 20m

$276

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 5/29

8:47 am-9:15 am

3 stops25h 28m

$286

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/8

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Compare providers for flights from Detroit to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Panama City

What is the cheapest month to book a flight from Detroit to Panama City?

Currently, June is the cheapest month in which you can book a flight from Detroit to Panama City (average of $610). Flying from Detroit to Panama City in February is currently the most expensive (average of $775). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Detroit to Panama City?

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Detroit to Panama City?

    Airlines like United Airlines fly from Detroit to Panama City in about 10h 57m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 2302 mi.

  • What are the cheapest airlines flying from Detroit to Panama City round-trip?

    Flying on Copa Airlines is currently your cheapest option to Panama City, with prices starting at $514. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $628 and $629, respectively. Copa Airlines is currently priced 40% below the average price you’ll pay for this route.

  • Can I find deals for flights from Detroit to Panama City that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

  • Can I find deals for business class flights from Detroit to Panama City?

    Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Detroit to Panama City (average of $610). Flying from Detroit to Panama City in February is currently the most expensive (average of $775). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Detroit to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Panama City flights
Detroit to Panama City flights
Midway to Panama City flights

Top 4 airlines flying from Detroit to Panama City

Discover the top 4 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$514Average$753FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$628Average$819FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$629Average$811FlexibilityNo cancel feeOn-time69%
DeltaCheapest$668Average$885FlexibilityNo cancel feeOn-timeN/A

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