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Panama City

$228+ Cheap flights from Detroit (DTT) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — PTY
helmi 1 — helmi 81
su 2/1
su 2/8
1 adult, Economy
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Cheap flight deals from Detroit to Panama City

Best flights from Detroit to Panama City
Discover carefully curated flight deals from Detroit to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated tammikuu 2, 2026.

This Avianca Connect deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 2/185:45 amDTW - PTY
2 stops18h 55mMultiple Airlines
to 2/262:55 amPTY - DTW
2 stops21h 04mMultiple Airlines
Deal found 12/30$474
This Delta deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 4/205:20 amDTW - PTY
1 stop8h 35mDelta
ma 5/42:20 pmPTY - DTW
1 stop9h 24mDelta
Deal found 12/31$609
This United Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 4/207:18 amDTW - PTY
2 stops12h 19mUnited Airlines
ma 5/49:45 amPTY - DTW
1 stop9h 53mUnited Airlines
Deal found 12/31$613
This Avianca Connect deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to 1/296:35 amDTW - PTY
2 stops18h 25mMultiple Airlines
ke 2/42:55 amPTY - DTW
2 stops21h 04mMultiple Airlines
Deal found 1/1$493
This Avianca Connect deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 1/145:15 amDTW - PTY
2 stops19h 25mMultiple Airlines
ti 1/202:55 amPTY - DTW
2 stops19h 49mMultiple Airlines
Deal found 12/31$509
This Avianca Connect deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 5/68:00 amDTW - PTY
2 stops17h 45mMultiple Airlines
ma 5/113:25 amPTY - DTW
2 stops19h 34mMultiple Airlines
Deal found 1/1$569
This Avianca Connect deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to 3/124:20 pmDTW - PTY
2 stops17h 30mMultiple Airlines
pe 3/209:45 amPTY - DTW
2 stops12h 56mMultiple Airlines
Deal found 12/31$603
This Avianca Connect deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
la 3/76:05 amDTW - PTY
2 stops18h 55mMultiple Airlines
pe 3/132:55 amPTY - DTW
2 stops20h 18mMultiple Airlines
Deal found 12/30$607
This Kiwi.com deal was found by Cheapflights users on 1/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 3/27:13 pmDTW - PTY
1 stop12h 53mMultiple Airlines
pe 3/69:33 pmPTY - DTW
1 stop13h 28mMultiple Airlines
Deal found 1/1$608

Find flight deals from Detroit to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated tammikuu 2, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$460
(Avianca Connect)

One-way from

$228
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$706
Provider with most accurate pricing for Detroit (DTT)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Panama City Tocumen Intl flights.
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From Detroit (DTT) to Panama City Tocumen Intl
Search Deals
One-way flight from Detroit (DTT) to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($194 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($53 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated tammikuu 2, 2026.
Use the filters below to find and compare flights from Detroit to Panama City that are best for you.

Fly from

Detroit

Fly to

Panama City

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

ke 2/18

5:45 am-12:40 am

2 stops18h 55m

Panama City Tocumen Intl

to 2/26

2:55 am-11:59 pm

2 stops21h 04m

$474

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

to 1/29

6:35 am-1:00 am

2 stops18h 25m

Panama City Tocumen Intl

ke 2/4

2:55 am-11:59 pm

2 stops21h 04m

$493

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

ke 1/14

5:15 am-12:40 am

2 stops19h 25m

Panama City Tocumen Intl

ti 1/20

2:55 am-10:44 pm

2 stops19h 49m

$509

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

ke 5/6

8:00 am-12:45 am

2 stops17h 45m

Panama City Tocumen Intl

ma 5/11

3:25 am-11:59 pm

2 stops19h 34m

$569

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

to 3/12

4:20 pm-8:50 am

2 stops17h 30m

Panama City Tocumen Intl

pe 3/20

9:45 am-11:41 pm

2 stops12h 56m

$603

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

la 3/7

6:05 am-1:00 am

2 stops18h 55m

Panama City Tocumen Intl

pe 3/13

2:55 am-12:13 am

2 stops20h 18m

$607

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

ma 3/2

7:13 pm-8:06 am

1 stop12h 53m

Panama City Tocumen Intl

pe 3/6

9:33 pm-11:01 am

1 stop13h 28m

$608

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

ma 4/20

5:20 am-12:55 pm

1 stop8h 35m

Panama City Tocumen Intl

ma 5/4

2:20 pm-12:44 am

1 stop9h 24m

$609

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

ma 4/20

7:18 am-6:37 pm

2 stops12h 19m

Panama City Tocumen Intl

ma 5/4

9:45 am-8:38 pm

1 stop9h 53m

$613

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

la 2/28

9:11 pm-1:00 am

2 stops27h 49m

$228

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/1

Showing 1-10 of 11 results
1
2

Compare providers for flights from Detroit to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Detroit-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Detroit-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Panama City

What is the cheapest month to book a flight from Detroit to Panama City?

Currently, June is the cheapest month in which you can book a flight from Detroit to Panama City (average of $592). Flying from Detroit to Panama City in February is currently the most expensive (average of $759). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated tammikuu 2, 2026.
See what other customers who have flown with United Airlines and American Airlines from Detroit to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,132 reviews

Food

6.6

Entertainment

7.1

Boarding

7.7

Crew

8.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
United Airlines
7.4
Good
9,132 reviews
United Airlines
7.4
Good
9,132 reviews

Food

6.6

Entertainment

7.1

Boarding

7.7

Crew

8.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
American Airlines
7.2
Good
11,074 reviews
United Airlines
7.4
Good
9,132 reviews

Food

6.6

Entertainment

7.1

Boarding

7.7

Crew

8.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit to Panama City round-trip?

    Flying on American Airlines is currently your cheapest option to Panama City, with prices starting at $578. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $608 and $608, respectively. American Airlines is currently priced 29% below the average price you’ll pay for this route.

  • Can I find deals for flights from Detroit to Panama City that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

  • Can I find deals for business class flights from Detroit to Panama City?

    Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Detroit to Panama City (average of $592). Flying from Detroit to Panama City in February is currently the most expensive (average of $759). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Detroit to Panama City

Discover the top 3 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated tammikuu 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$578Average$814FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$608Average$811FlexibilityNo cancel feeOn-time69%
DeltaCheapest$608Average$934FlexibilityNo cancel feeOn-timeN/A

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