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Panama City

$212+ Cheap flights from Detroit (DTT) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — PTY
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Avianca Connect deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:23 pmDTW - PTY
2 stops20h 37mMultiple Airlines
Wed 1/212:55 amPTY - DTW
2 stops21h 04mMultiple Airlines
Deal found 12/17$684
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:22 pmDTW - PTY
2 stops29h 38mMultiple Airlines
Sun 12/289:25 amPTY - DTW
1 stop8h 44mMultiple Airlines
Deal found 12/17$822
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:20 amDTW - PTY
2 stops23h 52mMultiple Airlines
Thu 1/19:33 pmPTY - DTW
1 stop24h 43mMultiple Airlines
Deal found 12/15$836
This United Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amDTW - PTY
1 stop8h 45mUnited Airlines
Thu 1/84:41 pmPTY - DTW
2 stops17h 29mUnited Airlines
Deal found 12/18$858
This American Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:30 amDTW - PTY
1 stop8h 23mAmerican Airlines
Thu 1/82:27 pmPTY - DTW
1 stop9h 30mAmerican Airlines
Deal found 12/18$904
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:06 pmDTW - PTY
1 stop25h 27mMultiple Airlines
Thu 1/19:33 pmPTY - DTW
1 stop24h 43mMultiple Airlines
Deal found 12/15$908
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:20 amDTW - PTY
2 stops18h 40mMultiple Airlines
Sun 12/213:39 pmPTY - DTW
1 stop9h 03mMultiple Airlines
Deal found 12/16$940

Find flight deals from Detroit to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$487
(Kiwi.com)

One-way from

$212
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$1,354
Provider with most accurate pricing for Detroit (DTT)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Panama City Tocumen Intl flights.
Search Deals
From Detroit (DTT) to Panama City Tocumen Intl
Search Deals
One-way flight from Detroit (DTT) to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($179 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($54 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Detroit to Panama City that are best for you.

Fly from

Detroit

Fly to

Panama City

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 2/19

10:16 am-1:00 am

2 stops14h 44m

Panama City Tocumen Intl

Tue 2/24

2:55 am-7:57 pm

2 stops17h 02m

$428

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 2/11

6:36 pm-2:00 pm

2 stops19h 24m

Panama City Tocumen Intl

Tue 2/24

2:55 am-7:57 pm

2 stops17h 02m

$527

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 3/24

4:20 pm-8:50 am

2 stops17h 30m

Panama City Tocumen Intl

Tue 3/31

3:20 am-7:46 pm

2 stops15h 26m

$550

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 1/30

5:15 am-12:40 am

2 stops19h 25m

Panama City Tocumen Intl

Thu 2/5

2:55 am-10:12 pm

2 stops19h 17m

$562

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 1/21

5:15 am-12:40 am

2 stops19h 25m

Panama City Tocumen Intl

Fri 1/23

2:55 am-11:59 pm

2 stops21h 04m

$566

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sun 2/1

1:43 pm-12:40 am

2 stops34h 57m

Panama City Tocumen Intl

Sun 2/8

9:33 pm-11:16 am

1 stop13h 43m

$567

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 1/16

6:35 am-12:40 am

2 stops18h 05m

Panama City Tocumen Intl

Thu 1/22

2:55 am-10:44 pm

2 stops19h 49m

$572

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 1/21

5:30 am-12:40 am

2 stops19h 10m

Panama City Tocumen Intl

Sun 1/25

5:50 pm-11:59 pm

2 stops30h 09m

$577

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 2/25

5:28 pm-2:00 pm

3 stops44h 32m

$212

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 1/21

5:30 am-1:27 pm

1 stop7h 57m

$429

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Compare providers for flights from Detroit to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Detroit-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Detroit-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Panama City

What is the cheapest month to book a flight from Detroit to Panama City?

Currently, June is the cheapest month in which you can book a flight from Detroit to Panama City (average of $592). Flying from Detroit to Panama City in February is currently the most expensive (average of $759). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to PTY?

Find hourly flight availability from Detroit to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 71% on flights from Detroit to Panama City by exploring options for tickets in the evening.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 18, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Detroit to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,091 reviews
Delta
7.9
Good
8,005 reviews

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,005 reviews

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit to Panama City round-trip?

    Flying on American Airlines is currently your cheapest option to Panama City, with prices starting at $578. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $608 and $608, respectively. American Airlines is currently priced 29% below the average price you’ll pay for this route.

  • Can I find deals for flights from Detroit to Panama City that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

  • Can I find deals for business class flights from Detroit to Panama City?

    Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Detroit to Panama City (average of $592). Flying from Detroit to Panama City in February is currently the most expensive (average of $759). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Detroit to Panama City

Discover the top 3 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$578Average$803FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$608Average$811FlexibilityNo cancel feeOn-time69%
DeltaCheapest$608Average$958FlexibilityNo cancel feeOn-timeN/A

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