What are the cheapest airlines flying from Detroit to Panama City round-trip?

Flying on Delta is currently your cheapest option to Panama City, with prices starting at $608. Additional round-trip tickets that might be worth considering are offered by United Airlines and American Airlines, with the lowest prices starting at $608 and $628, respectively. Delta is currently priced 27% below the average price you’ll pay for this route.

What is the cheapest day to fly from Detroit to Panama City?

Travelers seeking maximum savings on their Detroit to Panama City flight should consider departing on Wednesday evenings when fares are most often at their lowest. Friday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the most popular airlines that fly from Detroit to Panama City?

Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from Detroit to Panama City.

What is the cheapest day to fly round-trip from Detroit to Panama City?

Thursday flights are generally found to be more expensive for flights from Detroit to Panama City. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Panama City.

What is the cheapest month to fly from Detroit to Panama City?

August can be a great time to fly to Panama City from Detroit with a flight ticket averaging about $835. Cheapflights users have found deals in the month of August for as cheap as $608. The most expensive prices can be found in the month of September.

Can I find deals for flights from Detroit to Panama City that include hotel bookings?

Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Detroit to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

Can I find deals for business class flights from Detroit to Panama City?

Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$189+ Flights from Detroit to Panama City

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Cheap flight deals from Detroit to Panama City

Round-trip from	$418 (Avianca Connect)
One-way from	$189 (Avianca Connect)
Popular in	September
Cheapest in	August
Average price	$608

From Detroit (DTT) to Panama City Tocumen Intl

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One-way flight from Detroit (DTT) to Panama City Tocumen Intl

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Highest demand for flights based on searches. 14% potential increase in price ($136 potential increase over avg. RT price).

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Cheapest flight prices on average. 8% potential price decrease ($67 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

Tue 9/306:35 amDTW - PTY

2 stops15h 35mMultiple Airlines

Mon 10/63:25 amPTY - DTW

2 stops19h 04mMultiple Airlines

Deal found 8/16

$418

Mon 9/156:30 amDTW - PTY

2 stops15h 40mMultiple Airlines

Mon 9/2210:05 pmPTY - DTW

2 stops21h 09mMultiple Airlines

Deal found 8/16

$422

Fri 9/196:30 amDTW - PTY

2 stops15h 40mMultiple Airlines

Mon 9/2210:05 pmPTY - DTW

2 stops21h 09mMultiple Airlines

Deal found 8/17

$423

Sat 10/116:17 amDTW - PTY

2 stops15h 53mMultiple Airlines

Tue 10/143:20 amPTY - DTW

2 stops19h 09mMultiple Airlines

Deal found 8/16

$483

Thu 10/96:17 amDTW - PTY

1 stop11h 08mMultiple Airlines

Thu 10/1610:25 amPTY - DTW

1 stop8h 30mMultiple Airlines

Deal found 8/16

$484

Thu 10/96:17 amDTW - PTY

1 stop11h 08mMultiple Airlines

Mon 10/138:10 amPTY - DTW

1 stop10h 45mMultiple Airlines

Deal found 8/16

$490

Wed 10/86:41 amDTW - PTY

1 stop14h 38mMultiple Airlines

Wed 10/1512:03 pmPTY - DTW

1 stop10h 26mMultiple Airlines

Deal found 8/16

$515

Best flights from Detroit to Panama City
Discover carefully curated flight deals from Detroit to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 18, 2025.

Tue 9/306:35 amDTW - PTY

2 stops15h 35mMultiple Airlines

Mon 10/63:25 amPTY - DTW

2 stops19h 04mMultiple Airlines

Deal found 8/16

$418

Mon 9/156:30 amDTW - PTY

2 stops15h 40mMultiple Airlines

Mon 9/2210:05 pmPTY - DTW

2 stops21h 09mMultiple Airlines

Deal found 8/16

$422

Fri 9/196:30 amDTW - PTY

2 stops15h 40mMultiple Airlines

Mon 9/2210:05 pmPTY - DTW

2 stops21h 09mMultiple Airlines

Deal found 8/17

$423

Fri 11/147:00 amDTW - PTY

2 stops17h 40mMultiple Airlines

Sun 11/162:55 pmPTY - DTW

2 stops23h 14mMultiple Airlines

Deal found 8/16

$423

Thu 10/96:17 amDTW - PTY

2 stops15h 53mMultiple Airlines

Mon 10/133:25 amPTY - DTW

2 stops19h 04mMultiple Airlines

Deal found 8/16

$470

Sat 10/116:17 amDTW - PTY

2 stops15h 53mMultiple Airlines

Wed 10/1510:05 pmPTY - DTW

2 stops20h 50mMultiple Airlines

Deal found 8/16

$472

Thu 10/96:17 amDTW - PTY

1 stop11h 08mMultiple Airlines

Thu 10/1610:25 amPTY - DTW

1 stop8h 30mMultiple Airlines

Deal found 8/16

$484

Last-minute flights from Detroit to Panama City
Discover last-minute flight deals from Detroit to Panama City. Data last updated August 18, 2025 and is based on user searches.

Mon 8/259:40 amDTW - PTY

2 stops16h 05mMultiple Airlines

Mon 9/110:05 pmPTY - DTW

2 stops19h 35mMultiple Airlines

Deal found 8/18

$489

Mon 8/2510:40 amDTW - PTY

1 stop8h 57mUnited Airlines

Mon 9/13:30 pmPTY - DTW

2 stops17h 23mUnited Airlines

Deal found 8/18

$891

Mon 9/156:30 amDTW - PTY

2 stops15h 40mMultiple Airlines

Mon 9/2210:05 pmPTY - DTW

2 stops21h 09mMultiple Airlines

Deal found 8/16

$422

Fri 9/196:30 amDTW - PTY

2 stops15h 40mMultiple Airlines

Mon 9/2210:05 pmPTY - DTW

2 stops21h 09mMultiple Airlines

Deal found 8/17

$423

Tue 9/306:41 amDTW - PTY

1 stop14h 38mMultiple Airlines

Tue 10/712:03 pmPTY - DTW

1 stop10h 26mMultiple Airlines

Deal found 8/16

$516

One-way flights from Detroit to Panama City
Search for one-way flight options from Detroit to Panama City. Find affordable one-way fares based on user searches. Data last updated August 18, 2025.

Fri 10/176:41 amDTW - PTY

2 stops15h 29mMultiple Airlines

Deal found 8/16

$189

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 9/30

6:35 am-9:10 pm

2 stops15h 35m

Panama City Tocumen Intl

Mon 10/6

3:25 am-11:29 pm

2 stops19h 04m

$418

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 9/15

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Mon 9/22

10:05 pm-8:14 pm

2 stops21h 09m

$422

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 9/19

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Mon 9/22

10:05 pm-8:14 pm

2 stops21h 09m

$423

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 11/14

7:00 am-12:40 am

2 stops17h 40m

Panama City Tocumen Intl

Sun 11/16

2:55 pm-2:09 pm

2 stops23h 14m

$423

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 10/9

6:17 am-9:10 pm

2 stops15h 53m

Panama City Tocumen Intl

Mon 10/13

3:25 am-11:29 pm

2 stops19h 04m

$470

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 10/11

6:17 am-9:10 pm

2 stops15h 53m

Panama City Tocumen Intl

Wed 10/15

10:05 pm-7:55 pm

2 stops20h 50m

$472

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 10/9

6:17 am-4:25 pm

1 stop11h 08m

Panama City Tocumen Intl

Thu 10/16

10:25 am-7:55 pm

1 stop8h 30m

$484

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 10/17

6:41 am-9:10 pm

2 stops15h 29m

$189

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Panama City

What is the cheapest month to book a flight from Detroit to Panama City?

Currently, October is the cheapest month in which you can book a flight from Detroit to Panama City (average of $478). Flying from Detroit to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to PTY?

Unlike at noon, when flights are generally more expensive, you can save up to 15% on flights from Detroit to Panama City by exploring options for tickets in the morning.

Reviews of airlines servicing Panama City

See what other customers who have flown with Delta, United Airlines, and American Airlines from Detroit to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,981 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,925 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Detroit to Panama City round-trip?
Flying on Delta is currently your cheapest option to Panama City, with prices starting at $608. Additional round-trip tickets that might be worth considering are offered by United Airlines and American Airlines, with the lowest prices starting at $608 and $628, respectively. Delta is currently priced 27% below the average price you’ll pay for this route.
Can I find deals for flights from Detroit to Panama City that include hotel bookings?
Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Detroit to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.
Can I find deals for business class flights from Detroit to Panama City?
Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Detroit to Panama City?
Currently, October is the cheapest month in which you can book a flight from Detroit to Panama City (average of $478). Flying from Detroit to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Detroit to Panama City

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$608	Average$851	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$608	Average$896	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$628	Average$799	FlexibilityNo cancel fee	On-time71%

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$189+ Cheap flights from Detroit (DTT) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Detroit to Panama City with Cheapflights

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2. Select your favorite providers

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Cheap flight deals from Detroit to Panama City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama CityExplore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit to Panama City that are best for you.

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Panama City

What is the cheapest month to book a flight from Detroit to Panama City?

What is the cheapest time of day to fly from DTT to PTY?

Find hourly flight availability from Detroit to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

Reviews of airlines servicing Panama City

See what other customers who have flown with Delta, United Airlines, and American Airlines from Detroit to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Detroit to Panama City round-trip?

Can I find deals for flights from Detroit to Panama City that include hotel bookings?

How can I find direct flights from Detroit to Panama City?

Can I find deals for business class flights from Detroit to Panama City?

What is the cheapest month to book a flight from Detroit to Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Detroit to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Detroit to Panama City

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Travel Smart

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.