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Panama City

$183+ Cheap flights from Detroit (DTT) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — PTY
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Avianca Connect deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:05 am
DTW
-
PTY
2 stops15h 55m
Multiple Airlines
Tue 3/242:55 pm
PTY
-
DTW
2 stops20h 25m
Multiple Airlines
Deal found 2/1$452
This Avianca Connect deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1910:16 am
DTW
-
PTY
2 stops14h 44m
Multiple Airlines
Tue 2/242:55 am
PTY
-
DTW
2 stops16h 57m
Multiple Airlines
Deal found 1/31$472
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/110:59 pm
DTW
-
PTY
2 stops17h 56m
Multiple Airlines
Sun 3/810:26 am
PTY
-
DTW
1 stop20h 41m
Multiple Airlines
Deal found 2/1$480
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:09 am
DTW
-
PTY
2 stops27h 41m
Multiple Airlines
Wed 3/259:45 am
PTY
-
DTW
2 stops25h 35m
Multiple Airlines
Deal found 2/3$485
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:03 pm
DTW
-
PTY
1 stop13h 03m
Multiple Airlines
Thu 2/269:33 pm
PTY
-
DTW
1 stop12h 13m
Multiple Airlines
Deal found 2/2$486
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/237:28 pm
DTW
-
PTY
1 stop13h 12m
Multiple Airlines
Wed 2/259:33 pm
PTY
-
DTW
1 stop10h 58m
Multiple Airlines
Deal found 2/2$492
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:13 pm
DTW
-
PTY
1 stop12h 53m
Multiple Airlines
Fri 3/139:33 pm
PTY
-
DTW
1 stop14h 58m
Multiple Airlines
Deal found 2/2$494
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/59:02 am
DTW
-
PTY
1 stop11h 17m
Multiple Airlines
Mon 3/912:03 pm
PTY
-
DTW
1 stop11h 36m
Multiple Airlines
Deal found 2/2$497
This Avianca Connect deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:49 am
DTW
-
PTY
2 stops17h 11m
Multiple Airlines
Wed 3/189:45 am
PTY
-
DTW
2 stops13h 14m
Multiple Airlines
Deal found 2/1$498
This Avianca Connect deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:00 am
DTW
-
PTY
2 stops21h 05m
Multiple Airlines
Fri 5/13:05 am
PTY
-
DTW
2 stops19h 54m
Multiple Airlines
Deal found 2/1$501
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:13 pm
DTW
-
PTY
1 stop12h 53m
Multiple Airlines
Thu 3/128:01 am
PTY
-
DTW
1 stop9h 31m
Multiple Airlines
Deal found 2/2$505

Find flight deals from Detroit to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$452
(Avianca Connect)

One-way from

$183
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$849
Provider with most accurate pricing for Detroit (DTT)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Panama City Tocumen Intl flights.
Search Deals
From Detroit (DTT) to Panama City Tocumen Intl
Search Deals
One-way flight from Detroit (DTT) to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($93 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($36 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Detroit to Panama City that are best for you.

Fly from

Detroit

Fly to

Panama City

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 3/17

10:05 am-1:00 am

2 stops15h 55m

Panama City Tocumen Intl

Tue 3/24

2:55 pm-12:20 pm

2 stops20h 25m

$452

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 2/19

10:16 am-1:00 am

2 stops14h 44m

Panama City Tocumen Intl

Tue 2/24

2:55 am-7:52 pm

2 stops16h 57m

$472

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 2/23

7:28 pm-8:40 am

1 stop13h 12m

Panama City Tocumen Intl

Wed 2/25

9:33 pm-8:31 am

1 stop10h 58m

$492

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 4/25

5:00 am-1:05 am

2 stops21h 05m

Panama City Tocumen Intl

Fri 5/1

3:05 am-11:59 pm

2 stops19h 54m

$501

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 3/12

5:20 am-1:00 am

2 stops20h 40m

Panama City Tocumen Intl

Mon 3/16

5:50 pm-12:20 pm

2 stops17h 30m

$523

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 3/19

5:20 am-1:00 am

2 stops20h 40m

Panama City Tocumen Intl

Thu 3/26

9:45 am-11:59 pm

2 stops13h 14m

$526

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 2/19

10:16 am-1:00 am

2 stops14h 44m

Panama City Tocumen Intl

Wed 2/25

2:55 am-9:39 pm

2 stops18h 44m

$532

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 3/5

8:49 am-1:00 am

2 stops16h 11m

Panama City Tocumen Intl

Fri 3/13

2:55 am-11:59 pm

2 stops20h 04m

$566

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 2/17

5:45 am-1:00 am

2 stops19h 15m

Panama City Tocumen Intl

Mon 2/23

2:55 am-9:00 pm

2 stops18h 05m

$567

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 3/7

7:24 pm-4:55 pm

3 stops45h 31m

$183

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/31

Showing 1-10 of 13 results
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Compare providers for flights from Detroit to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Panama City

What is the cheapest month to book a flight from Detroit to Panama City?

Currently, June is the cheapest month in which you can book a flight from Detroit to Panama City (average of $592). Flying from Detroit to Panama City in February is currently the most expensive (average of $811). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Detroit to Panama City?

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit to Panama City round-trip?

    Flying on American Airlines is currently your cheapest option to Panama City, with prices starting at $578. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $608 and $629, respectively. American Airlines is currently priced 28% below the average price you’ll pay for this route.

  • Can I find deals for flights from Detroit to Panama City that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

  • Can I find deals for business class flights from Detroit to Panama City?

    Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Detroit to Panama City (average of $592). Flying from Detroit to Panama City in February is currently the most expensive (average of $811). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Detroit to Panama City

Discover the top 3 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$578Average$816FlexibilityNo cancel feeOn-time71%
DeltaCheapest$608Average$934FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$629Average$811FlexibilityNo cancel feeOn-time69%

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