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$290+ Cheap flights from Detroit (DTT) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — PTY
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Detroit to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$386
(Avianca Connect)

One-way from

$290
(Avianca Connect)

Popular in

September

Cheapest in

August

Average price

$1,558
From Detroit (DTT) to Panama City Tocumen Intl
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One-way flight from Detroit (DTT) to Panama City Tocumen Intl
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Highest demand for flights based on searches. 14% potential increase in price ($135 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($66 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Avianca Connect deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:05 amDTW - PTY
2 stops18h 55mMultiple Airlines
Wed 11/52:55 amPTY - DTW
2 stops15h 59mMultiple Airlines
Deal found 9/15$386
This Avianca Connect deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:17 amDTW - PTY
2 stops15h 53mMultiple Airlines
Sun 10/262:55 amPTY - DTW
2 stops16h 05mMultiple Airlines
Deal found 9/15$450
This Avianca Connect deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:43 amDTW - PTY
2 stops18h 27mMultiple Airlines
Wed 10/223:20 amPTY - DTW
2 stops19h 10mMultiple Airlines
Deal found 9/14$480
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:22 amDTW - PTY
1 stop13h 21mMultiple Airlines
Sat 11/89:25 amPTY - DTW
1 stop8h 01mMultiple Airlines
Deal found 9/14$541
This Avianca Connect deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/79:00 amDTW - PTY
2 stops15h 40mMultiple Airlines
Sun 11/165:55 pmPTY - DTW
2 stops20h 14mMultiple Airlines
Deal found 9/14$544

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Detroit to Panama City that are best for you.

Fly from

Detroit

Fly to

Panama City

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 10/30

7:05 am-1:00 am

2 stops18h 55m

Panama City Tocumen Intl

Wed 11/5

2:55 am-6:54 pm

2 stops15h 59m

$386

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 10/23

6:17 am-12:10 am

2 stops18h 53m

Panama City Tocumen Intl

Sun 10/26

2:55 am-8:00 pm

2 stops16h 05m

$450

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 10/18

6:43 am-12:10 am

2 stops18h 27m

Panama City Tocumen Intl

Wed 10/22

3:20 am-11:30 pm

2 stops19h 10m

$480

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 11/1

7:22 am-7:43 pm

1 stop13h 21m

Panama City Tocumen Intl

Sat 11/8

9:25 am-5:26 pm

1 stop8h 01m

$541

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 11/7

9:00 am-12:40 am

2 stops15h 40m

Panama City Tocumen Intl

Sun 11/16

5:55 pm-2:09 pm

2 stops20h 14m

$544

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 9/26

6:30 am-12:45 am

2 stops19h 15m

Panama City Tocumen Intl

Sun 10/5

10:05 pm-8:00 pm

2 stops20h 55m

$575

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 12/12

6:11 am-12:40 am

2 stops18h 29m

$290

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 12/13

6:11 am-1:00 am

2 stops18h 49m

$290

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sun 12/14

7:00 am-7:25 pm

3 stops36h 25m

$352

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Panama City

What is the cheapest month to book a flight from Detroit to Panama City?

Currently, October is the cheapest month in which you can book a flight from Detroit to Panama City (average of $478). Flying from Detroit to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to PTY?

Find hourly flight availability from Detroit to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 15% on flights from Detroit to Panama City by exploring options for tickets in the morning.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 16, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Detroit to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,924 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit to Panama City round-trip?

    Flying on American Airlines is currently your cheapest option to Panama City, with prices starting at $578. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $608 and $608, respectively. American Airlines is currently priced 30% below the average price you’ll pay for this route.

  • Can I find deals for flights from Detroit to Panama City that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

  • Can I find deals for business class flights from Detroit to Panama City?

    Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Detroit to Panama City (average of $478). Flying from Detroit to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Detroit to Panama City

Discover the top 3 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$578Average$781FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$608Average$851FlexibilityNo cancel feeOn-time69%
DeltaCheapest$608Average$927FlexibilityNo cancel feeOn-timeN/A

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