$114+ Cheap flights from St. Louis (STL) to Panama City Beach, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PNS
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Lambert-St Louis to Panama City Beach are usually found in December or November, booked 79 days in advance, depart on a Tuesday or Wednesday and return on a Thursday
Cheap flight deals from St. Louis to Panama City Beach
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to Panama City BeachExplore the most affordable flight options available from St. Louis to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from St. Louis to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:20 pm -
Nonstop1h 45m
Fri 9/115:10 pm -
Nonstop1h 45m
Deal found 8/5![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:20 am -
2 stops7h 45m
Fri 9/114:10 pm -
2 stops6h 00m
Deal found 8/7![Southwest logo]()
$257
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:55 pm -
Nonstop1h 45m
Sat 9/57:15 am -
Nonstop1h 50m
Deal found 8/6![Southwest logo]()
$258
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:46 pm -
1 stop5h 19m
Mon 9/146:20 pm -
1 stop5h 22m
Deal found 8/7![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:50 pm -
Nonstop1h 45m
Thu 9/245:10 pm -
Nonstop1h 45m
Deal found 8/9![Southwest logo]()
$286
Best flights from St. Louis to Panama City BeachDiscover carefully curated flight deals from St. Louis to Panama City Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from St. Louis to Panama City Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/611:45 am -
Nonstop1h 45m
Fri 9/114:10 pm -
2 stops6h 00m
Deal found 8/7![Southwest logo]()
$242
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/221:55 pm -
Nonstop1h 45m
Tue 9/293:45 pm -
Nonstop1h 50m
Deal found 8/6![Southwest logo]()
$289
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:45 am -
2 stops7h 05m
Thu 9/244:10 pm -
1 stop6h 00m
Deal found 8/7![Southwest logo]()
$304
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:25 am -
2 stops9h 50m
Fri 9/114:10 pm -
2 stops6h 00m
Deal found 8/5![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2011:30 am -
Nonstop1h 45m
Sat 9/2611:45 am -
Nonstop1h 45m
Deal found 8/5![Southwest logo]()
$372
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:40 am -
2 stops7h 40m
Mon 9/287:05 am -
2 stops8h 15m
Deal found 8/5![Southwest logo]()
$374
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:40 pm -
Nonstop1h 45m
Fri 10/94:00 pm -
Nonstop1h 50m
Deal found 8/9![Southwest logo]()
$379
Last-minute flights from St. Louis to Panama City BeachDiscover last-minute flight deals from St. Louis to Panama City Beach. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Panama City Beach. Data last updated August 10, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:55 pm -
Nonstop1h 45m
Sat 9/57:15 am -
Nonstop1h 50m
Deal found 8/6![Southwest logo]()
$258
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:20 pm -
Nonstop1h 45m
Fri 9/115:10 pm -
Nonstop1h 45m
Deal found 8/5![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:20 am -
2 stops7h 45m
Fri 9/114:10 pm -
2 stops6h 00m
Deal found 8/7![Southwest logo]()
$257
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:46 pm -
1 stop5h 19m
Mon 9/146:20 pm -
1 stop5h 22m
Deal found 8/7![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:50 pm -
Nonstop1h 45m
Thu 9/245:10 pm -
Nonstop1h 45m
Deal found 8/9![Southwest logo]()
$286
One-way flights from St. Louis to Panama City BeachSearch for one-way flight options from St. Louis to Panama City Beach. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from St. Louis to Panama City Beach. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:20 pm -
Nonstop1h 45m
Deal found 8/6![Southwest logo]()
$114
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:44 pm -
1 stop5h 56m
Deal found 8/6![Delta logo]()
$124
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:20 am -
2 stops7h 45m
Deal found 8/6![Southwest logo]()
$129
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:40 pm -
Nonstop1h 45m
Deal found 8/6![Southwest logo]()
$145
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:25 am -
1 stop6h 12m
Deal found 8/6![Delta logo]()
$150
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:54 pm -
1 stop4h 31m
Deal found 8/5![Delta logo]()
$175
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/101:45 pm -
Nonstop1h 45m
Deal found 8/5![Southwest logo]()
$182
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:35 pm -
1 stop5h 43m
Deal found 8/5![Delta logo]()
$187
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:00 pm -
2 stops7h 30m
Deal found 8/6![Southwest logo]()
$192
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:30 am -
2 stops14h 48m
Deal found 8/7![United Airlines logo]()
$195
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:25 am -
1 stop6h 06m
Deal found 8/6![Delta logo]()
$197
Find flight deals from St. Louis to Panama City Beach
Keep the following information in mind while searching for St. Louis to Panama City Beach flight deals. Data was last updated August 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (Southwest) |
One-way from | $114 (Southwest) |
Popular in | June |
Cheapest in | December |
Average price | $406 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Panama City Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from St. Louis to Panama City Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Sun 9/6
11:45 am-1:30 pm
Nonstop1h 45m
Panama City NW Florida Beaches
Fri 9/11
4:10 pm-10:10 pm
2 stops6h 00m
$242
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Tue 9/22
1:55 pm-3:40 pm
Nonstop1h 45m
Panama City NW Florida Beaches
Tue 9/29
3:45 pm-5:35 pm
Nonstop1h 50m
$289
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Mon 9/21
5:45 am-12:50 pm
2 stops7h 05m
Panama City NW Florida Beaches
Thu 9/24
4:10 pm-10:10 pm
1 stop6h 00m
$304
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Sat 9/5
8:25 am-6:15 pm
2 stops9h 50m
Panama City NW Florida Beaches
Fri 9/11
4:10 pm-10:10 pm
2 stops6h 00m
$337
Quickest round-trip
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Sun 9/20
11:30 am-1:15 pm
Nonstop1h 45m
Panama City NW Florida Beaches
Sat 9/26
11:45 am-1:30 pm
Nonstop1h 45m
$372
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Fri 9/25
7:40 am-3:20 pm
2 stops7h 40m
Panama City NW Florida Beaches
Mon 9/28
7:05 am-3:20 pm
2 stops8h 15m
$374
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Fri 10/2
3:40 pm-5:25 pm
Nonstop1h 45m
Panama City NW Florida Beaches
Fri 10/9
4:00 pm-5:50 pm
Nonstop1h 50m
$379
Cheapest one-way
Quickest one-way
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Tue 10/6
12:55 pm-2:40 pm
Nonstop1h 45m
$145
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Wed 10/7
7:20 pm-11:18 pm
1 stop3h 58m
$150
St. LouisPanama City
STL Lambert-St Louis - ECP Panama City NW Florida Beaches
STLECP
Lambert-St Louis
Wed 11/4
10:25 am-4:37 pm
1 stop6h 12m
$150
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Panama City Beach
Have a flexible travel schedule? Discover the best time to fly to Panama City Beach from St. Louis with our price prediction graph.
STL-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Panama City Beach
STL-PA9
STL-ECP
What is the cheapest time of day to fly from STL to PA9?
Find hourly flight availability from St. Louis to Panama City Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 10, 2026.
It’s optimal to fly from St. Louis to Panama City Beach in the evening. By choosing this option you can save up to 16% on the cost of your flight, compared to a flight in the morning.
How much does it cost to fly round-trip from St. Louis to Panama City Beach?
Airfare is below average for this route at the moment.
St. Louis to Panama City Beach flights typically cost between $316 and $488 in September.The cheapest round-trip price found within the last 5 days was $227 on Southwest (Sep 5-Sep 11).
Reviews of airlines servicing Panama City Beach
Get insights into the airlines that provide service to Panama City Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City Beach. Reviews last updated August 10, 2026.
Read through reviews of airlines operating flights from St. Louis to Panama City Beach, such as Southwest,Delta, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Panama City Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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St. Louis and Panama City Beach flights
Browse other St. Louis and Panama City Beach flight options. Last updated on August 10, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on August 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
St. Louis to Panama City Beach flights
Consider these flights traveling from St. Louis to Panama City Beach.
Top 4 airlines flying from St. Louis to Panama City Beach
Discover the top 4 airlines that operate flights from St. Louis to Panama City Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$98 | Average$211 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$175 | Average$389 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$185 | Average$393 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$227 | Average$426 | FlexibilityNo cancel fee | On-time63% |