$149+ Cheap flights from St. Louis (STL) to Panama City Beach, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PNS
Jul 23 — Jul 301
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Panama City Beach with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Lambert-St Louis to Panama City Beach are usually found in December or November, booked 26 days in advance, depart on a Tuesday or Wednesday and return on a Thursday
Cheap flight deals from St. Louis to Panama City Beach
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to Panama City BeachExplore the most affordable flight options available from St. Louis to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
Explore the most affordable flight options available from St. Louis to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/183:40 pm
STL
- ECP
Nonstop1h 45m
Southwest
Sat 7/257:00 am
ECP
- STL
Nonstop1h 50m
Southwest
Deal found 6/21![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:58 pm
STL
- ECP
1 stop4h 39m
Delta
Sat 7/255:00 pm
ECP
- STL
1 stop6h 20m
Delta
Deal found 6/21![Delta logo]()
$307
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:00 am
STL
- ECP
2 stops8h 38m
United Airlines
Tue 8/251:47 pm
ECP
- STL
1 stop8h 13m
United Airlines
Deal found 6/21![United Airlines logo]()
$312
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:35 am
STL
- ECP
1 stop5h 17m
United Airlines
Sat 8/296:30 am
ECP
- STL
2 stops9h 01m
United Airlines
Deal found 6/21![United Airlines logo]()
$315
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:20 pm
STL
- ECP
Nonstop1h 45m
Southwest
Sat 8/157:15 am
ECP
- STL
Nonstop1h 50m
Southwest
Deal found 6/22![Southwest logo]()
$316
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/89:24 am
STL
- ECP
1 stop4h 30m
Delta
Sun 7/126:48 pm
ECP
- STL
1 stop5h 05m
Delta
Deal found 6/18![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:25 pm
STL
- ECP
Nonstop1h 50m
Southwest
Sat 7/116:05 pm
ECP
- STL
1 stop5h 10m
Southwest
Deal found 6/17![Southwest logo]()
$321
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:25 pm
STL
- ECP
Nonstop1h 50m
Southwest
Wed 7/225:30 pm
ECP
- STL
Nonstop1h 50m
Southwest
Deal found 6/18![Southwest logo]()
$325
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:23 pm
STL
- ECP
1 stop4h 17m
Delta
Mon 8/106:00 am
ECP
- STL
1 stop3h 54m
Delta
Deal found 6/22![Delta logo]()
$326
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:45 pm
STL
- ECP
2 stops7h 45m
Southwest
Tue 8/117:45 am
ECP
- STL
2 stops8h 40m
Southwest
Deal found 6/21![Southwest logo]()
$327
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:20 pm
STL
- ECP
1 stop7h 50m
Southwest
Tue 7/284:20 pm
ECP
- STL
2 stops7h 25m
Southwest
Deal found 6/20![Southwest logo]()
$328
Best flights from St. Louis to Panama City BeachDiscover carefully curated flight deals from St. Louis to Panama City Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
Discover carefully curated flight deals from St. Louis to Panama City Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:45 am
STL
- ECP
1 stop4h 05m
Southwest
Sat 8/157:15 am
ECP
- STL
Nonstop1h 50m
Southwest
Deal found 6/20![Southwest logo]()
$307
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:58 pm
STL
- ECP
1 stop4h 39m
Delta
Tue 8/46:00 am
ECP
- STL
1 stop3h 54m
Delta
Deal found 6/22![Delta logo]()
$376
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:10 am
STL
- ECP
Nonstop1h 50m
Southwest
Thu 8/205:10 pm
ECP
- STL
Nonstop1h 45m
Southwest
Deal found 6/22![Southwest logo]()
$316
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:05 pm
STL
- ECP
Nonstop1h 50m
Southwest
Thu 8/61:30 pm
ECP
- STL
2 stops6h 25m
Southwest
Deal found 6/20![Southwest logo]()
$331
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/209:24 am
STL
- ECP
1 stop4h 30m
Delta
Wed 7/225:03 pm
ECP
- STL
1 stop5h 12m
Delta
Deal found 6/21![Delta logo]()
$398
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:45 am
STL
- ECP
2 stops7h 25m
Southwest
Sat 9/129:30 am
ECP
- STL
1 stop6h 00m
Southwest
Deal found 6/21![Southwest logo]()
$341
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/233:55 pm
STL
- ECP
Nonstop1h 45m
Southwest
Tue 7/285:30 pm
ECP
- STL
Nonstop1h 50m
Southwest
Deal found 6/19![Southwest logo]()
$382
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:50 am
STL
- ECP
2 stops7h 40m
Southwest
Wed 8/511:30 am
ECP
- STL
2 stops8h 30m
Southwest
Deal found 6/22![Southwest logo]()
$391
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:40 am
STL
- ECP
1 stop5h 10m
Southwest
Sun 7/197:10 pm
ECP
- STL
Nonstop1h 50m
Southwest
Deal found 6/18![Southwest logo]()
$392
Last-minute flights from St. Louis to Panama City BeachDiscover last-minute flight deals from St. Louis to Panama City Beach. Data last updated June 23, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Panama City Beach. Data last updated June 23, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/89:24 am
STL
- ECP
1 stop4h 30m
Delta
Sun 7/126:48 pm
ECP
- STL
1 stop5h 05m
Delta
Deal found 6/18![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:25 pm
STL
- ECP
Nonstop1h 50m
Southwest
Sat 7/116:05 pm
ECP
- STL
1 stop5h 10m
Southwest
Deal found 6/17![Southwest logo]()
$321
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/114:40 pm
STL
- ECP
1 stop5h 20m
Southwest
Tue 7/145:30 pm
ECP
- STL
Nonstop1h 50m
Southwest
Deal found 6/18![Southwest logo]()
$345
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:25 pm
STL
- ECP
Nonstop1h 50m
Southwest
Wed 7/225:30 pm
ECP
- STL
Nonstop1h 50m
Southwest
Deal found 6/18![Southwest logo]()
$325
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/183:40 pm
STL
- ECP
Nonstop1h 45m
Southwest
Sat 7/257:00 am
ECP
- STL
Nonstop1h 50m
Southwest
Deal found 6/21![Southwest logo]()
$297
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:12 pm
STL
- ECP
1 stop5h 25m
American Airlines
Thu 7/233:13 pm
ECP
- STL
1 stop6h 35m
American Airlines
Deal found 6/18![American Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:58 pm
STL
- ECP
1 stop4h 39m
Delta
Sat 7/255:00 pm
ECP
- STL
1 stop6h 20m
Delta
Deal found 6/21![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:20 pm
STL
- ECP
1 stop7h 50m
Southwest
Tue 7/284:20 pm
ECP
- STL
2 stops7h 25m
Southwest
Deal found 6/20![Southwest logo]()
$328
One-way flights from St. Louis to Panama City BeachSearch for one-way flight options from St. Louis to Panama City Beach. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
Search for one-way flight options from St. Louis to Panama City Beach. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/183:40 pm
STL
- ECP
Nonstop1h 45m
Southwest
Deal found 6/20![Southwest logo]()
$149
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:00 am
STL
- ECP
1 stop3h 42m
Delta
Deal found 6/22![Delta logo]()
$154
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:10 am
STL
- ECP
1 stop5h 17m
American Airlines
Deal found 6/18![American Airlines logo]()
$159
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:25 pm
STL
- ECP
Nonstop1h 50m
Southwest
Deal found 6/18![Southwest logo]()
$163
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:45 am
STL
- ECP
2 stops7h 25m
Southwest
Deal found 6/22![Southwest logo]()
$164
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1410:51 am
STL
- ECP
1 stop5h 21m
Delta
Deal found 6/18![Delta logo]()
$168
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:59 pm
STL
- ECP
1 stop4h 04m
Delta
Deal found 6/22![Delta logo]()
$173
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:20 pm
STL
- ECP
Nonstop1h 45m
Southwest
Deal found 6/17![Southwest logo]()
$184
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:39 pm
STL
- ECP
1 stop4h 29m
Delta
Deal found 6/18![Delta logo]()
$189
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:12 pm
STL
- ECP
1 stop5h 25m
American Airlines
Deal found 6/21![American Airlines logo]()
$194
Find flight deals from St. Louis to Panama City Beach
Keep the following information in mind while searching for St. Louis to Panama City Beach flight deals. Data was last updated June 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $297 (Southwest) |
One-way from | $149 (Southwest) |
Popular in | June |
Cheapest in | December |
Average price | $445 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Panama City Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from St. Louis to Panama City Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Sat 8/8
5:45 am-9:50 am
1 stop4h 05m
Panama City NW Florida Beaches
Sat 8/15
7:15 am-9:05 am
Nonstop1h 50m
$307
Quickest round-trip
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Sat 8/15
10:10 am-12:00 pm
Nonstop1h 50m
Panama City NW Florida Beaches
Thu 8/20
5:10 pm-6:55 pm
Nonstop1h 45m
$316
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Sat 8/1
7:05 pm-8:55 pm
Nonstop1h 50m
Panama City NW Florida Beaches
Thu 8/6
1:30 pm-7:55 pm
2 stops6h 25m
$331
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Wed 9/9
10:45 am-6:10 pm
2 stops7h 25m
Panama City NW Florida Beaches
Sat 9/12
9:30 am-3:30 pm
1 stop6h 00m
$341
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Sun 8/2
6:58 pm-11:37 pm
1 stop4h 39m
Panama City NW Florida Beaches
Tue 8/4
6:00 am-9:54 am
1 stop3h 54m
$376
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Thu 7/23
3:55 pm-5:40 pm
Nonstop1h 45m
Panama City NW Florida Beaches
Tue 7/28
5:30 pm-7:20 pm
Nonstop1h 50m
$382
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Sun 8/2
5:50 am-1:30 pm
2 stops7h 40m
Panama City NW Florida Beaches
Wed 8/5
11:30 am-8:00 pm
2 stops8h 30m
$391
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Fri 7/17
5:40 am-10:50 am
1 stop5h 10m
Panama City NW Florida Beaches
Sun 7/19
7:10 pm-9:00 pm
Nonstop1h 50m
$392
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Mon 7/20
9:24 am-1:54 pm
1 stop4h 30m
Panama City NW Florida Beaches
Wed 7/22
5:03 pm-10:15 pm
1 stop5h 12m
$398
Cheapest one-way
Quickest one-way
St. LouisPanama City
STL - ECP
STLECP
Lambert-St Louis
Sat 9/19
4:20 pm-6:05 pm
Nonstop1h 45m
$149
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Panama City Beach
Have a flexible travel schedule? Discover the best time to fly to Panama City Beach from St. Louis with our price prediction graph.
STL-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Panama City Beach
STL-PA9
STL-ECP
What is the cheapest time of day to fly from STL to PA9?
Find hourly flight availability from St. Louis to Panama City Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 23, 2026.
It’s optimal to fly from St. Louis to Panama City Beach in the evening. By choosing this option you can save up to 14% on the cost of your flight, compared to a flight in the morning.
How much does it cost to fly round-trip from St. Louis to Panama City Beach?
Reviews of airlines servicing Panama City Beach
Get insights into the airlines that provide service to Panama City Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City Beach. Reviews last updated June 23, 2026.
Read through reviews of airlines operating flights from St. Louis to Panama City Beach, such as Southwest,Delta, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Overall
7.9
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Boarding
8.1
Food
7.0
Overall
7.9
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Boarding
8.1
Food
7.0
Overall
7.9
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Boarding
8.1
Food
7.0
Overall
7.9
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Panama City Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for St. Louis to Panama City Beach
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Complete your trip
Complete your trip to Panama City Beach by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Panama City Beach by cabin class
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St. Louis and Panama City Beach flights
Browse other St. Louis and Panama City Beach flight options. Last updated on June 23, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on June 23, 2026.
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Check out other popular destinations found by fellow travelers in 2026
St. Louis to Panama City Beach flights
Consider these flights traveling from St. Louis to Panama City Beach.
Top 4 airlines flying from St. Louis to Panama City Beach
Discover the top 4 airlines that operate flights from St. Louis to Panama City Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$87 | Average$194 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$165 | Average$369 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$185 | Average$395 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$208 | Average$428 | FlexibilityNo cancel fee | On-time63% |