$168+ Cheap flights from Iowa to Panama City, FL (ECP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/17. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ECP
May 31 — Jun 71
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to Panama City
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Cheapest flights from Iowa to Panama CityExplore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
Explore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2026.
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:17 pm
MLI
- ECP
1 stop5h 34m
Delta
Sat 5/306:00 am
ECP
- MLI
1 stop4h 20m
Delta
Deal found 4/27![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:45 pm
MLI
- ECP
1 stop5h 51m
American Airlines
Tue 7/74:17 pm
ECP
- MLI
2 stops8h 24m
American Airlines
Deal found 4/26![American Airlines logo]()
$294
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:17 pm
MLI
- ECP
1 stop5h 44m
Delta
Wed 6/36:00 am
ECP
- MLI
1 stop4h 20m
Delta
Deal found 4/28![Delta logo]()
$303
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:00 am
MLI
- ECP
1 stop6h 56m
Delta
Sun 5/314:54 pm
ECP
- MLI
1 stop5h 27m
Delta
Deal found 4/28![Delta logo]()
$304
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:45 am
CID
- ECP
1 stop6h 41m
Delta
Fri 6/195:08 pm
ECP
- CID
1 stop4h 58m
Delta
Deal found 4/30![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1012:09 pm
CID
- ECP
2 stops11h 35m
Delta
Wed 6/172:46 pm
ECP
- CID
1 stop7h 20m
Delta
Deal found 4/30![Delta logo]()
$314
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/185:45 am
CID
- ECP
1 stop5h 09m
Delta
Mon 6/225:08 pm
ECP
- CID
1 stop4h 58m
Delta
Deal found 4/28![Delta logo]()
$317
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:56 am
MLI
- ECP
1 stop6h 54m
Delta
Sat 5/306:00 am
ECP
- MLI
1 stop4h 20m
Delta
Deal found 4/28![Delta logo]()
$317
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:39 pm
CID
- ECP
2 stops10h 45m
American Airlines
Sat 10/243:17 pm
ECP
- CID
1 stop8h 22m
American Airlines
Deal found 4/29![American Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:11 pm
CID
- ECP
2 stops7h 17m
Delta
Tue 6/22:50 pm
ECP
- CID
1 stop6h 24m
Delta
Deal found 4/28![Delta logo]()
$322
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:45 am
CID
- ECP
1 stop5h 09m
Delta
Tue 6/235:08 pm
ECP
- CID
1 stop4h 58m
Delta
Deal found 4/28![Delta logo]()
$326
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/185:07 pm
MLI
- ECP
1 stop5h 51m
Delta
Sat 7/255:00 pm
ECP
- MLI
1 stop5h 31m
Delta
Deal found 4/28![Delta logo]()
$327
Best flights from Iowa to Panama CityDiscover carefully curated flight deals from Iowa to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
Discover carefully curated flight deals from Iowa to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2026.
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:56 am
MLI
- ECP
1 stop4h 58m
Delta
Tue 7/76:00 am
ECP
- MLI
1 stop4h 22m
Delta
Deal found 4/26![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:45 pm
MLI
- ECP
1 stop5h 51m
American Airlines
Tue 7/74:17 pm
ECP
- MLI
2 stops8h 24m
American Airlines
Deal found 4/26![American Airlines logo]()
$294
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:45 pm
OMA
- ECP
1 stop4h 20m
Southwest
Tue 7/77:00 am
ECP
- OMA
1 stop7h 35m
Southwest
Deal found 4/25![Southwest logo]()
$369
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:54 am
CID
- ECP
1 stop5h 27m
United Airlines
Tue 6/162:05 pm
ECP
- CID
1 stop7h 26m
United Airlines
Deal found 4/26![United Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:17 pm
MLI
- ECP
1 stop5h 34m
Delta
Sat 5/306:00 am
ECP
- MLI
1 stop4h 20m
Delta
Deal found 4/30![Delta logo]()
$289
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:00 am
MLI
- ECP
1 stop6h 56m
Delta
Sun 5/314:54 pm
ECP
- MLI
1 stop5h 27m
Delta
Deal found 4/28![Delta logo]()
$304
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:45 am
CID
- ECP
1 stop5h 09m
Delta
Tue 6/165:08 pm
ECP
- CID
1 stop4h 58m
Delta
Deal found 4/30![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:59 pm
OMA
- ECP
1 stop5h 36m
American Airlines
Mon 7/136:54 pm
ECP
- OMA
1 stop5h 26m
American Airlines
Deal found 4/29![American Airlines logo]()
$407
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/42:35 pm
OMA
- ECP
1 stop3h 55m
Southwest
Fri 7/1012:00 pm
ECP
- OMA
2 stops9h 20m
Southwest
Deal found 4/27![Southwest logo]()
$408
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/185:45 am
CID
- ECP
1 stop5h 09m
Delta
Mon 6/225:08 pm
ECP
- CID
1 stop4h 58m
Delta
Deal found 4/30![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/231:30 pm
DSM
- ECP
1 stop8h 30m
Southwest
Tue 7/288:05 am
ECP
- DSM
1 stop7h 00m
Southwest
Deal found 4/26![Southwest logo]()
$413
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:17 pm
MLI
- ECP
1 stop5h 50m
Delta
Mon 6/2211:59 am
ECP
- MLI
1 stop4h 38m
Delta
Deal found 4/28![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/210:55 am
OMA
- ECP
2 stops6h 45m
Southwest
Tue 7/77:00 am
ECP
- OMA
1 stop7h 35m
Southwest
Deal found 4/30![Southwest logo]()
$422
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:45 am
CID
- ECP
1 stop5h 09m
Delta
Tue 6/235:08 pm
ECP
- CID
1 stop4h 58m
Delta
Deal found 4/26![Delta logo]()
$326
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:10 pm
OMA
- ECP
1 stop5h 10m
Southwest
Fri 7/1012:00 pm
ECP
- OMA
2 stops9h 20m
Southwest
Deal found 4/27![Southwest logo]()
$422
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/123:00 pm
ALO
- ECP
2 stops8h 40m
American Airlines
Tue 6/163:23 pm
ECP
- ALO
2 stops8h 58m
American Airlines
Deal found 4/26![American Airlines logo]()
$518
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:45 am
CID
- ECP
1 stop5h 09m
Delta
Tue 6/165:08 pm
ECP
- CID
1 stop4h 58m
Delta
Deal found 4/28![Delta logo]()
$326
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/185:07 pm
MLI
- ECP
1 stop5h 51m
Delta
Sat 7/255:00 pm
ECP
- MLI
1 stop5h 31m
Delta
Deal found 4/28![Delta logo]()
$327
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:17 pm
MLI
- ECP
1 stop5h 44m
Delta
Sat 5/236:00 am
ECP
- MLI
1 stop4h 20m
Delta
Deal found 4/27![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/193:00 pm
ALO
- ECP
2 stops8h 40m
American Airlines
Tue 6/2312:22 pm
ECP
- ALO
2 stops11h 59m
American Airlines
Deal found 4/28![American Airlines logo]()
$584
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/124:45 pm
OMA
- ECP
1 stop3h 40m
Southwest
Sat 5/167:55 am
ECP
- OMA
1 stop4h 00m
Southwest
Deal found 4/27![Southwest logo]()
$487
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:57 am
DSM
- ECP
1 stop6h 39m
Delta
Wed 6/39:19 am
ECP
- DSM
1 stop4h 18m
Delta
Deal found 4/30![Delta logo]()
$335
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:45 am
OMA
- ECP
2 stops8h 30m
Southwest
Sun 5/315:35 am
ECP
- OMA
1 stop4h 10m
Southwest
Deal found 4/28![Southwest logo]()
$499
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/183:00 pm
ALO
- ECP
2 stops8h 40m
American Airlines
Mon 6/223:23 pm
ECP
- ALO
2 stops8h 58m
American Airlines
Deal found 4/28![American Airlines logo]()
$613
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1711:28 am
DSM
- ECP
1 stop7h 15m
Delta
Wed 6/241:31 pm
ECP
- DSM
1 stop4h 23m
Delta
Deal found 4/26![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:23 pm
ALO
- ECP
1 stop22h 13m
American Airlines
Mon 5/181:06 pm
ECP
- ALO
1 stop24h 47m
American Airlines
Deal found 4/29![American Airlines logo]()
$625
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:41 pm
DSM
- ECP
1 stop4h 10m
Delta
Wed 6/107:41 am
ECP
- DSM
1 stop5h 54m
Delta
Deal found 4/26![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/253:02 pm
ALO
- ECP
1 stop23h 42m
American Airlines
Tue 6/23:14 pm
ECP
- ALO
1 stop23h 23m
American Airlines
Deal found 4/28![American Airlines logo]()
$639
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/57:01 am
OMA
- ECP
1 stop6h 55m
Delta
Sat 7/115:00 pm
ECP
- OMA
1 stop6h 48m
Delta
Deal found 4/27![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:00 am
ALO
- ECP
1 stop9h 44m
American Airlines
Tue 6/23:14 pm
ECP
- ALO
1 stop23h 23m
American Airlines
Deal found 4/28![American Airlines logo]()
$639
Last-minute flights from Iowa to Panama CityDiscover last-minute flight deals from Iowa to Panama City. Data last updated May 1, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Panama City. Data last updated May 1, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:17 pm
MLI
- ECP
1 stop6h 11m
Delta
Tue 5/1911:40 am
ECP
- MLI
1 stop4h 57m
Delta
Deal found 4/30![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:15 am
MLI
- ECP
1 stop7h 21m
American Airlines
Tue 5/1911:43 am
ECP
- MLI
2 stops6h 27m
American Airlines
Deal found 4/30![American Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:17 pm
MLI
- ECP
1 stop5h 44m
Delta
Sat 5/236:00 am
ECP
- MLI
1 stop4h 20m
Delta
Deal found 4/27![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/193:48 pm
MLI
- ECP
1 stop6h 32m
American Airlines
Sat 5/2311:00 am
ECP
- MLI
2 stops7h 26m
American Airlines
Deal found 4/27![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:17 pm
MLI
- ECP
1 stop5h 34m
Delta
Sat 5/306:00 am
ECP
- MLI
1 stop4h 20m
Delta
Deal found 4/27![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/244:45 pm
MLI
- ECP
1 stop5h 51m
American Airlines
Sat 5/307:05 am
ECP
- MLI
2 stops11h 21m
American Airlines
Deal found 4/30![American Airlines logo]()
$332
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:45 am
CID
- ECP
1 stop5h 04m
Delta
Wed 6/32:50 pm
ECP
- CID
1 stop6h 24m
Delta
Deal found 4/28![Delta logo]()
$317
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:56 am
MLI
- ECP
1 stop6h 54m
Delta
Sat 5/306:00 am
ECP
- MLI
1 stop4h 20m
Delta
Deal found 4/28![Delta logo]()
$317
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:41 pm
DSM
- ECP
1 stop4h 20m
Delta
Tue 6/25:29 pm
ECP
- DSM
1 stop5h 03m
Delta
Deal found 4/28![Delta logo]()
$335
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:17 pm
MLI
- ECP
1 stop5h 44m
Delta
Sat 5/305:29 pm
ECP
- MLI
1 stop4h 52m
Delta
Deal found 4/28![Delta logo]()
$303
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:00 am
MLI
- ECP
1 stop6h 56m
Delta
Sun 5/314:54 pm
ECP
- MLI
1 stop5h 27m
Delta
Deal found 4/28![Delta logo]()
$304
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:11 pm
CID
- ECP
2 stops7h 17m
Delta
Tue 6/22:50 pm
ECP
- CID
1 stop6h 24m
Delta
Deal found 4/28![Delta logo]()
$322
One-way flights from Iowa to Panama CitySearch for one-way flight options from Iowa to Panama City. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
Search for one-way flight options from Iowa to Panama City. Find affordable one-way fares based on user searches. Data last updated May 1, 2026.
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:00 am
DSM
- ECP
1 stop7h 21m
United Airlines
Deal found 4/27![United Airlines logo]()
$168
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:33 pm
OMA
- ECP
1 stop5h 11m
Delta
Deal found 4/30![Delta logo]()
$168
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/44:09 pm
OMA
- ECP
1 stop5h 50m
Delta
Deal found 4/27![Delta logo]()
$170
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:10 am
DSM
- ECP
2 stops8h 36m
American Airlines
Deal found 4/27![American Airlines logo]()
$173
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:39 pm
DSM
- ECP
1 stop5h 05m
Delta
Deal found 4/27![Delta logo]()
$188
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:41 am
DSM
- ECP
1 stop5h 07m
Delta
Deal found 4/28![Delta logo]()
$204
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:03 pm
OMA
- ECP
1 stop6h 34m
American Airlines
Deal found 4/30![American Airlines logo]()
$204
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/171:10 pm
OMA
- ECP
2 stops8h 00m
Southwest
Deal found 4/30![Southwest logo]()
$205
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:30 am
DSM
- ECP
2 stops9h 13m
American Airlines
Deal found 4/28![American Airlines logo]()
$209
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:10 am
OMA
- ECP
1 stop9h 15m
Southwest
Deal found 4/30![Southwest logo]()
$209
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/231:30 pm
DSM
- ECP
2 stops8h 10m
Southwest
Deal found 4/28![Southwest logo]()
$219
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/312:10 pm
OMA
- ECP
2 stops9h 30m
Southwest
Deal found 4/30![Southwest logo]()
$219
Find flight deals from Iowa to Panama City
Keep the following information in mind while searching for Iowa to Panama City flight deals. Data was last updated May 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $289 (Delta) |
One-way from | $168 (United Airlines) |
Popular in | November |
Cheapest in | August |
Average price | $399 |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MolinePanama City
MLI - ECP
MLIECP
Moline Quad-City
Tue 6/23
5:56 am-10:54 am
1 stop4h 58m
Panama City NW Florida Beaches
Tue 7/7
6:00 am-10:22 am
1 stop4h 22m
$289
MolinePanama City
MLI - ECP
MLIECP
Moline Quad-City
Sun 5/24
5:17 pm-10:51 pm
1 stop5h 34m
Panama City NW Florida Beaches
Sat 5/30
6:00 am-10:20 am
1 stop4h 20m
$289
MolinePanama City
MLI - ECP
MLIECP
Moline Quad-City
Tue 6/23
4:45 pm-10:36 pm
1 stop5h 51m
Panama City NW Florida Beaches
Tue 7/7
4:17 pm-12:41 am
2 stops8h 24m
$294
MolinePanama City
MLI - ECP
MLIECP
Moline Quad-City
Thu 5/28
11:00 am-5:56 pm
1 stop6h 56m
Panama City NW Florida Beaches
Sun 5/31
4:54 pm-10:21 pm
1 stop5h 27m
$304
Cedar RapidsPanama City
CID - ECP
CIDECP
Cedar Rapids
Wed 6/10
5:45 am-10:54 am
1 stop5h 09m
Panama City NW Florida Beaches
Tue 6/16
5:08 pm-10:06 pm
1 stop4h 58m
$309
Cedar RapidsPanama City
CID - ECP
CIDECP
Cedar Rapids
Thu 6/18
5:45 am-10:54 am
1 stop5h 09m
Panama City NW Florida Beaches
Mon 6/22
5:08 pm-10:06 pm
1 stop4h 58m
$309
MolinePanama City
MLI - ECP
MLIECP
Moline Quad-City
Sat 6/20
5:17 pm-11:07 pm
1 stop5h 50m
Panama City NW Florida Beaches
Mon 6/22
11:59 am-4:37 pm
1 stop4h 38m
$317
Cedar RapidsPanama City
CID - ECP
CIDECP
Cedar Rapids
Fri 6/19
5:45 am-10:54 am
1 stop5h 09m
Panama City NW Florida Beaches
Tue 6/23
5:08 pm-10:06 pm
1 stop4h 58m
$326
Cedar RapidsPanama City
CID - ECP
CIDECP
Cedar Rapids
Fri 6/12
5:45 am-10:54 am
1 stop5h 09m
Panama City NW Florida Beaches
Tue 6/16
5:08 pm-10:06 pm
1 stop4h 58m
$326
MolinePanama City
MLI - ECP
MLIECP
Moline Quad-City
Sat 7/18
5:07 pm-10:58 pm
1 stop5h 51m
Panama City NW Florida Beaches
Sat 7/25
5:00 pm-10:31 pm
1 stop5h 31m
$327
Showing 1-10 of 52 resultsSorted by cheapest first
Best time to book a flight from Iowa to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Iowa with our price prediction graph.
OMA-ECP
DSM-ECP
CID-ECP
MLI-ECP
ALO-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Panama City
USIA-ECP
OMA-ECP
DSM-ECP
CID-ECP
MLI-ECP
What is the cheapest month to book a flight from Iowa to Panama City, Florida?
Currently, October is the cheapest month in which you can book a flight from Iowa to Panama City, Florida (average of $187). Flying from Iowa to Panama City, Florida in April is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Iowa to Panama City, Florida?
Related info for your journey
Find useful and relevant information for your journey from Iowa to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Iowa to Panama City
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Panama City by cabin class
Find flights from Iowa to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Panama City flights
Browse other Iowa and Panama City flight options. Last updated on May 1, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Iowa to Panama City flights
Consider these flights traveling from Iowa to Panama City.
Top 4 airlines flying from Iowa to Panama City
Discover the top 4 airlines that operate flights from Iowa to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$239 | Average$431 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$377 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$253 | Average$474 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$297 | Average$392 | FlexibilityNo cancel fee | On-time63% |