$159+ Cheap flights from Iowa to Panama City, FL (ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ECP
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Panama City with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to Panama City
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Cheapest flights from Iowa to Panama CityExplore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:17 pm -
1 stop5h 15m
Thu 12/37:04 am -
1 stop7h 09m
Deal found 10/29![Delta logo]()
$315
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:36 am -
1 stop6h 21m
Tue 12/11:38 pm -
1 stop4h 28m
Deal found 10/28![Delta logo]()
$317
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:53 pm -
1 stop4h 24m
Fri 12/119:23 am -
1 stop4h 50m
Deal found 10/28![Delta logo]()
$337
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:05 am -
1 stop5h 29m
Tue 12/85:16 pm -
1 stop5h 54m
Deal found 10/28![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:05 am -
1 stop5h 29m
Thu 12/241:59 pm -
2 stops9h 09m
Deal found 10/29![Delta logo]()
$344
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:15 am -
2 stops8h 46m
Mon 12/211:59 pm -
2 stops9h 09m
Deal found 10/25![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:00 am -
1 stop8h 18m
Thu 12/39:05 am -
2 stops11h 28m
Deal found 10/29![United Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:01 pm -
1 stop7h 51m
Sat 11/147:53 am -
1 stop6h 53m
Deal found 10/26![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:00 am -
2 stops9h 11m
Sat 11/145:16 pm -
1 stop5h 53m
Deal found 10/26![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
2 stops10h 18m
Sat 11/1411:30 am -
2 stops10h 05m
Deal found 10/26![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:10 am -
2 stops9h 50m
Thu 12/37:55 am -
2 stops12h 55m
Deal found 10/29![Southwest logo]()
$395
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:05 am -
2 stops10h 13m
Tue 12/11:58 pm -
1 stop7h 27m
Deal found 10/28![United Airlines logo]()
$404
Best flights from Iowa to Panama CityDiscover carefully curated flight deals from Iowa to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Iowa to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:17 pm -
1 stop5h 15m
Thu 12/37:04 am -
1 stop7h 09m
Deal found 10/29![Delta logo]()
$315
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/305:00 am -
2 stops11h 05m
Tue 2/22:10 pm -
1 stop5h 04m
Deal found 10/30![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/93:31 pm -
1 stop5h 38m
Tue 2/1611:09 am -
1 stop7h 55m
Deal found 10/25![American Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/57:00 am -
2 stops11h 15m
Wed 3/37:50 am -
2 stops13h 40m
Deal found 10/27![Southwest logo]()
$377
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:53 pm -
1 stop4h 24m
Fri 12/119:23 am -
1 stop4h 50m
Deal found 10/28![Delta logo]()
$337
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:05 am -
1 stop5h 29m
Tue 12/85:16 pm -
1 stop5h 54m
Deal found 10/28![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:10 am -
2 stops9h 50m
Thu 12/37:55 am -
2 stops12h 55m
Deal found 10/29![Southwest logo]()
$395
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:05 am -
1 stop5h 29m
Thu 12/241:59 pm -
2 stops9h 09m
Deal found 10/27![Delta logo]()
$344
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/912:52 pm -
2 stops8h 48m
Tue 2/164:40 pm -
1 stop5h 50m
Deal found 10/25![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/238:00 am -
1 stop5h 27m
Wed 1/279:02 am -
2 stops10h 12m
Deal found 10/29![United Airlines logo]()
$444
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/245:20 am -
2 stops6h 55m
Wed 3/241:40 pm -
1 stop7h 00m
Deal found 10/26![Southwest logo]()
$482
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/308:00 am -
1 stop5h 27m
Wed 2/32:56 pm -
1 stop7h 34m
Deal found 10/25![United Airlines logo]()
$455
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:00 am -
1 stop5h 17m
Tue 12/81:58 pm -
1 stop7h 50m
Deal found 10/25![United Airlines logo]()
$464
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/153:00 pm -
1 stop6h 35m
Thu 3/184:55 pm -
1 stop5h 38m
Deal found 10/28![United Airlines logo]()
$497
Last-minute flights from Iowa to Panama CityDiscover last-minute flight deals from Iowa to Panama City. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Panama City. Data last updated October 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:01 pm -
1 stop7h 51m
Sat 11/147:53 am -
1 stop6h 53m
Deal found 10/26![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:00 am -
2 stops9h 11m
Sat 11/145:16 pm -
1 stop5h 53m
Deal found 10/26![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
2 stops10h 18m
Sat 11/1411:30 am -
2 stops10h 05m
Deal found 10/26![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:31 pm -
1 stop5h 28m
Thu 11/196:49 pm -
1 stop5h 37m
Deal found 10/28![American Airlines logo]()
$416
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:52 pm -
1 stop4h 32m
Fri 11/276:00 am -
1 stop4h 44m
Deal found 10/27![Delta logo]()
$418
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:17 pm -
1 stop5h 15m
Thu 12/37:04 am -
1 stop7h 09m
Deal found 10/29![Delta logo]()
$315
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:36 am -
1 stop6h 21m
Tue 12/11:38 pm -
1 stop4h 28m
Deal found 10/28![Delta logo]()
$317
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:00 am -
1 stop8h 18m
Thu 12/39:05 am -
2 stops11h 28m
Deal found 10/29![United Airlines logo]()
$352
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:10 am -
2 stops9h 50m
Thu 12/37:55 am -
2 stops12h 55m
Deal found 10/29![Southwest logo]()
$395
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:05 am -
2 stops10h 13m
Tue 12/11:58 pm -
1 stop7h 27m
Deal found 10/28![United Airlines logo]()
$404
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:10 am -
2 stops9h 40m
Tue 12/17:30 am -
2 stops13h 20m
Deal found 10/28![Southwest logo]()
$458
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:15 am -
1 stop5h 08m
Fri 12/44:06 pm -
1 stop7h 04m
Deal found 10/29![Delta logo]()
$339
One-way flights from Iowa to Panama CitySearch for one-way flight options from Iowa to Panama City. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Iowa to Panama City. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:36 am -
1 stop6h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Delta logo]()
$159
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:52 pm -
1 stop4h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Delta logo]()
$188
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:10 am -
2 stops8h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Southwest logo]()
$213
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:52 pm -
1 stop4h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Delta logo]()
$224
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/221:58 pm -
2 stops9h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![American Airlines logo]()
$254
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:52 pm -
1 stop5h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![American Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1011:00 am -
2 stops9h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/155:26 am -
1 stop5h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$310
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/166:35 am -
2 stops9h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![United Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1710:12 am -
2 stops10h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/145:30 pm -
2 stops19h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Delta logo]()
$503
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/132:11 pm -
2 stops9h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$510
Find flight deals from Iowa to Panama City
Keep the following information in mind while searching for Iowa to Panama City flight deals. Data was last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $315 (Delta) |
One-way from | $159 (Delta) |
Popular in | July |
Cheapest in | December |
Average price | $358 |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesPanama City
DSM Des Moines - ECP Panama City NW Florida Beaches
DSMECP
Des Moines
Thu 11/26
11:36 am-5:57 pm
1 stop6h 21m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$159
Des MoinesPanama City
DSM Des Moines - ECP Panama City NW Florida Beaches
DSMECP
Des Moines
Mon 11/23
6:52 pm-11:24 pm
1 stop4h 32m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$188
Des MoinesPanama City
DSM Des Moines - ECP Panama City NW Florida Beaches
DSMECP
Des Moines
Thu 11/26
6:10 am-2:50 pm
2 stops8h 40m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$213
Des MoinesPanama City
DSM Des Moines - ECP Panama City NW Florida Beaches
DSMECP
Des Moines
Sun 11/22
6:52 pm-11:24 pm
1 stop4h 32m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$224
Des MoinesPanama City
DSM Des Moines - ECP Panama City NW Florida Beaches
DSMECP
Des Moines
Sun 11/22
1:58 pm-11:47 pm
2 stops9h 49m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$254
Cedar RapidsPanama City
CID Cedar Rapids - ECP Panama City NW Florida Beaches
CIDECP
Cedar Rapids
Thu 12/10
3:52 pm-8:55 pm
1 stop5h 03m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
Quickest round-trip
Cedar RapidsPanama City
CID Cedar Rapids - ECP Panama City NW Florida Beaches
CIDECP
Cedar Rapids
Wed 3/17
5:45 am-10:15 am
1 stop4h 30m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$284
Cedar RapidsPanama City
CID Cedar Rapids - ECP Panama City NW Florida Beaches
CIDECP
Cedar Rapids
Thu 12/10
11:00 am-8:55 pm
2 stops9h 55m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$289
Cedar RapidsPanama City
CID Cedar Rapids - ECP Panama City NW Florida Beaches
CIDECP
Cedar Rapids
Mon 3/15
5:26 am-10:39 am
1 stop5h 13m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$310
Des MoinesPanama City
DSM Des Moines - ECP Panama City NW Florida Beaches
DSMECP
Des Moines
Thu 11/26
4:17 pm-9:32 pm
1 stop5h 15m
Panama City NW Florida Beaches
Thu 12/3
7:04 am-2:13 pm
1 stop7h 09m
$315
Showing 1-10 of 28 resultsSorted by cheapest first
Best time to book a flight from Iowa to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Iowa with our price prediction graph.
DSM-ECP
CID-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Panama City
USIA-ECP
DSM-ECP
CID-ECP
What is the cheapest month to book a flight from Iowa to Panama City, Florida?
Currently, December is the cheapest month in which you can book a flight from Iowa to Panama City, Florida (average of $308). Flying from Iowa to Panama City, Florida in October is currently the most expensive (average of $495). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Iowa to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Panama City
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Panama City by cabin class
Find flights from Iowa to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Panama City flights
Browse other Iowa and Panama City flight options. Last updated on October 30, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Iowa to Panama City flights
Consider these flights traveling from Iowa to Panama City.
Top 4 airlines flying from Iowa to Panama City
Discover the top 4 airlines that operate flights from Iowa to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$269 | Average$406 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$271 | Average$431 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$342 | Average$503 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$374 | Average$406 | FlexibilityNo cancel fee | On-time63% |