$134+ Cheap flights from Iowa to Panama City, FL (ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ECP
Oct 18 — Oct 251
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Iowa to Panama CityExplore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
Explore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:50 pm -
1 stop4h 35m
Tue 11/37:55 am -
1 stop7h 00m
Deal found 9/16![Southwest logo]()
$267
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:40 pm -
2 stops7h 58m
Sat 12/121:30 pm -
2 stops9h 50m
Deal found 9/15![United Airlines logo]()
$278
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:22 am -
1 stop7h 20m
Sat 11/146:05 pm -
1 stop5h 21m
Deal found 9/16![American Airlines logo]()
$281
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:42 pm -
1 stop5h 36m
Tue 10/205:34 pm -
1 stop5h 32m
Deal found 9/15![Delta logo]()
$285
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:00 am -
1 stop5h 32m
Sat 11/143:05 pm -
2 stops8h 37m
Deal found 9/16![United Airlines logo]()
$286
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:45 pm -
1 stop6h 18m
Wed 11/49:19 am -
1 stop4h 57m
Deal found 9/16![Delta logo]()
$291
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:54 pm -
1 stop4h 24m
Wed 11/49:19 am -
1 stop5h 57m
Deal found 9/16![Delta logo]()
$301
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:34 pm -
1 stop6h 06m
Tue 1/57:01 pm -
1 stop5h 08m
Deal found 9/14![American Airlines logo]()
$301
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:45 pm -
1 stop6h 18m
Tue 11/310:14 am -
1 stop7h 32m
Deal found 9/15![Delta logo]()
$303
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:43 pm -
1 stop5h 35m
Wed 11/46:00 am -
1 stop5h 15m
Deal found 9/16![Delta logo]()
$306
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:20 am -
2 stops8h 10m
Wed 11/44:10 pm -
2 stops5h 55m
Deal found 9/16![Southwest logo]()
$311
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:34 pm -
1 stop6h 19m
Mon 10/266:42 pm -
1 stop5h 56m
Deal found 9/18![American Airlines logo]()
$312
Best flights from Iowa to Panama CityDiscover carefully curated flight deals from Iowa to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
Discover carefully curated flight deals from Iowa to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:40 pm -
2 stops7h 58m
Sat 12/121:30 pm -
2 stops9h 50m
Deal found 9/15![United Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:45 pm -
1 stop6h 18m
Tue 11/310:14 am -
1 stop7h 32m
Deal found 9/15![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:20 am -
2 stops8h 10m
Wed 11/44:10 pm -
2 stops5h 55m
Deal found 9/16![Southwest logo]()
$311
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:32 am -
1 stop6h 05m
Mon 11/26:00 am -
1 stop5h 15m
Deal found 9/16![Delta logo]()
$306
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:05 am -
2 stops8h 05m
Tue 11/37:30 am -
2 stops9h 25m
Deal found 9/15![Southwest logo]()
$324
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:43 pm -
1 stop5h 35m
Wed 11/46:00 am -
1 stop5h 15m
Deal found 9/16![Delta logo]()
$306
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:41 am -
1 stop7h 41m
Fri 10/24:27 pm -
1 stop6h 45m
Deal found 9/17![American Airlines logo]()
$682
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:03 am -
2 stops10h 15m
Wed 11/1111:30 am -
1 stop7h 58m
Deal found 9/15![United Airlines logo]()
$370
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:13 pm -
1 stop6h 11m
Tue 11/245:16 pm -
1 stop5h 52m
Deal found 9/13![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:26 am -
2 stops10h 10m
Tue 11/34:55 pm -
1 stop7h 00m
Deal found 9/16![United Airlines logo]()
$383
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:04 pm -
1 stop4h 02m
Wed 10/216:00 am -
1 stop4h 18m
Deal found 9/13![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:20 am -
1 stop10h 45m
Tue 10/2710:05 am -
2 stops10h 35m
Deal found 9/14![Southwest logo]()
$399
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/275:55 am -
1 stop6h 44m
Sat 3/611:15 am -
1 stop5h 07m
Deal found 9/17![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:00 am -
2 stops11h 10m
Mon 11/911:25 am -
2 stops10h 40m
Deal found 9/14![Southwest logo]()
$426
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:05 am -
1 stop4h 01m
Thu 11/1911:25 am -
1 stop4h 57m
Deal found 9/13![Delta logo]()
$341
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:45 am -
2 stops8h 18m
Wed 10/76:20 am -
2 stops10h 00m
Deal found 9/17![United Airlines logo]()
$463
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1311:05 am -
1 stop7h 01m
Sat 11/216:00 am -
1 stop4h 23m
Deal found 9/13![Delta logo]()
$341
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:10 am -
2 stops10h 15m
Thu 10/221:50 pm -
2 stops8h 20m
Deal found 9/15![Southwest logo]()
$493
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:42 pm -
1 stop5h 36m
Tue 10/136:20 pm -
1 stop4h 46m
Deal found 9/17![Delta logo]()
$351
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:55 am -
2 stops7h 36m
Sun 11/87:10 am -
1 stop5h 59m
Deal found 9/14![American Airlines logo]()
$690
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop4h 30m
Wed 11/2511:25 am -
1 stop4h 57m
Deal found 9/13![Delta logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:56 pm -
1 stop5h 21m
Tue 10/207:05 am -
1 stop8h 21m
Deal found 9/14![American Airlines logo]()
$717
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:46 pm -
2 stops27h 32m
Thu 10/222:08 pm -
1 stop7h 21m
Deal found 9/15![United Airlines logo]()
$609
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:54 pm -
1 stop4h 24m
Wed 10/146:00 am -
1 stop4h 42m
Deal found 9/16![Delta logo]()
$372
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:54 am -
2 stops7h 25m
Mon 11/306:49 pm -
1 stop5h 09m
Deal found 9/13![American Airlines logo]()
$784
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:46 pm -
2 stops27h 32m
Tue 10/206:20 am -
2 stops16h 27m
Deal found 9/14![United Airlines logo]()
$657
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:09 pm -
1 stop6h 16m
Sun 10/46:00 am -
1 stop4h 13m
Deal found 9/14![Delta logo]()
$403
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:30 am -
2 stops12h 08m
Sun 12/134:50 pm -
3 stops17h 47m
Deal found 9/14![United Airlines logo]()
$659
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:09 pm -
1 stop3h 54m
Mon 10/56:00 am -
1 stop4h 13m
Deal found 9/17![Delta logo]()
$437
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:46 pm -
2 stops27h 32m
Tue 10/274:55 pm -
3 stops17h 29m
Deal found 9/14![United Airlines logo]()
$807
Last-minute flights from Iowa to Panama CityDiscover last-minute flight deals from Iowa to Panama City. Data last updated September 18, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Panama City. Data last updated September 18, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:42 pm -
1 stop5h 36m
Tue 10/205:34 pm -
1 stop5h 32m
Deal found 9/15![Delta logo]()
$285
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:04 pm -
1 stop4h 02m
Wed 10/216:00 am -
1 stop4h 18m
Deal found 9/14![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:34 pm -
1 stop6h 19m
Mon 10/266:42 pm -
1 stop5h 56m
Deal found 9/18![American Airlines logo]()
$312
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:45 pm -
1 stop6h 18m
Wed 11/49:19 am -
1 stop4h 57m
Deal found 9/16![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:50 pm -
1 stop4h 35m
Tue 11/37:55 am -
1 stop7h 00m
Deal found 9/16![Southwest logo]()
$267
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:54 pm -
1 stop4h 24m
Wed 11/49:19 am -
1 stop5h 57m
Deal found 9/16![Delta logo]()
$301
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:45 pm -
1 stop6h 18m
Tue 11/37:12 am -
1 stop7h 04m
Deal found 9/16![Delta logo]()
$306
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:20 am -
2 stops8h 10m
Wed 11/44:10 pm -
2 stops5h 55m
Deal found 9/16![Southwest logo]()
$311
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:45 pm -
1 stop6h 18m
Tue 11/310:14 am -
1 stop7h 32m
Deal found 9/15![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:55 am -
1 stop4h 20m
Tue 11/37:55 am -
2 stops9h 25m
Deal found 9/15![Southwest logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:22 am -
1 stop7h 20m
Sat 11/146:05 pm -
1 stop5h 21m
Deal found 9/16![American Airlines logo]()
$281
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:00 am -
1 stop5h 32m
Sat 11/143:05 pm -
2 stops8h 37m
Deal found 9/16![United Airlines logo]()
$286
One-way flights from Iowa to Panama CitySearch for one-way flight options from Iowa to Panama City. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
Search for one-way flight options from Iowa to Panama City. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:50 pm -
1 stop4h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$134
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:45 pm -
1 stop6h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$146
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:43 pm -
1 stop5h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$161
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:43 pm -
1 stop5h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Delta logo]()
$170
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:26 am -
2 stops10h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$179
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:59 pm -
1 stop5h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$219
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:34 pm -
1 stop6h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:20 am -
1 stop10h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Southwest logo]()
$224
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
2 stops12h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$230
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:15 pm -
2 stops10h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$252
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:22 am -
1 stop7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:04 pm -
1 stop6h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Delta logo]()
$306
Find flight deals from Iowa to Panama City
Keep the following information in mind while searching for Iowa to Panama City flight deals. Data was last updated September 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $267 (Southwest) |
One-way from | $134 (Southwest) |
Popular in | December |
Cheapest in | September |
Average price | $324 |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
OmahaPanama City
OMA Omaha Eppley Airfield - ECP Panama City NW Florida Beaches
OMAECP
Omaha Eppley Airfield
Wed 10/28
8:25 am-3:30 pm
2 stops7h 05m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$139
OmahaPanama City
OMA Omaha Eppley Airfield - ECP Panama City NW Florida Beaches
OMAECP
Omaha Eppley Airfield
Tue 10/27
1:45 pm-8:03 pm
1 stop6h 18m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$146
OmahaPanama City
OMA Omaha Eppley Airfield - ECP Panama City NW Florida Beaches
OMAECP
Omaha Eppley Airfield
Thu 10/29
5:43 pm-11:18 pm
1 stop5h 35m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$161
OmahaPanama City
OMA Omaha Eppley Airfield - ECP Panama City NW Florida Beaches
OMAECP
Omaha Eppley Airfield
Fri 10/23
5:43 pm-11:18 pm
1 stop5h 35m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$170
OmahaPanama City
OMA Omaha Eppley Airfield - ECP Panama City NW Florida Beaches
OMAECP
Omaha Eppley Airfield
Tue 10/27
11:26 am-9:36 pm
2 stops10h 10m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$179
Des MoinesPanama City
DSM Des Moines - ECP Panama City NW Florida Beaches
DSMECP
Des Moines
Thu 11/19
2:59 pm-8:57 pm
1 stop5h 58m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$219
Des MoinesPanama City
DSM Des Moines - ECP Panama City NW Florida Beaches
DSMECP
Des Moines
Fri 10/23
6:20 am-5:05 pm
1 stop10h 45m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$224
Des MoinesPanama City
DSM Des Moines - ECP Panama City NW Florida Beaches
DSMECP
Des Moines
Fri 10/23
1:15 pm-11:53 pm
2 stops10h 38m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$252
Des MoinesPanama City
DSM Des Moines - ECP Panama City NW Florida Beaches
DSMECP
Des Moines
Sat 10/24
11:22 am-6:42 pm
1 stop7h 20m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$269
OmahaPanama City
OMA Omaha Eppley Airfield - ECP Panama City NW Florida Beaches
OMAECP
Omaha Eppley Airfield
Sat 12/5
1:40 pm-9:38 pm
2 stops7h 58m
Panama City NW Florida Beaches
Sat 12/12
1:30 pm-11:20 pm
2 stops9h 50m
$278
Showing 1-10 of 50 resultsSorted by cheapest first
Best time to book a flight from Iowa to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Iowa with our price prediction graph.
OMA-ECP
DSM-ECP
MLI-ECP
CID-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Panama City
USIA-ECP
OMA-ECP
DSM-ECP
MLI-ECP
CID-ECP
What is the cheapest month to book a flight from Iowa to Panama City, Florida?
Currently, December is the cheapest month in which you can book a flight from Iowa to Panama City, Florida (average of $308). Flying from Iowa to Panama City, Florida in March is currently the most expensive (average of $485). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Iowa to Panama City, Florida?
Airfare is below average for this route at the moment.
Iowa to Panama City, Florida flights typically cost between $324 and $354 in October.The cheapest round-trip price found within the last 5 days was $281 on American Airlines (Oct 31-Nov 14).
Related info for your journey
Find useful and relevant information for your journey from Iowa to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Iowa to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Panama City by cabin class
Find flights from Iowa to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Panama City flights
Browse other Iowa and Panama City flight options. Last updated on September 18, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Iowa to Panama City flights
Consider these flights traveling from Iowa to Panama City.
Top 4 airlines flying from Iowa to Panama City
Discover the top 4 airlines that operate flights from Iowa to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$402 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$271 | Average$447 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$342 | Average$503 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$374 | Average$406 | FlexibilityNo cancel fee | On-time63% |