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Panama City

$157+ Cheap flights from Iowa to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ECP
dic. 3 — dic. 101
mié. 12/3
mié. 12/10
1 adult, Economy
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Find flight deals from Iowa to Panama City

Cheapest flights from Iowa to Panama City
Explore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 3, 2025.

This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/155:54 amCID - ECP
1 stop4h 32mDelta
mié. 11/195:00 pmECP - CID
1 stop5h 38mDelta
Deal found 11/3$309
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/158:00 amCID - ECP
2 stops8h 24mUnited Airlines
mié. 11/196:30 amECP - CID
2 stops12h 36mUnited Airlines
Deal found 11/3$319
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/36:12 pmOMA - ECP
1 stop4h 25mDelta
mié. 12/1012:33 pmECP - OMA
1 stop8h 56mDelta
Deal found 11/3$319
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/32:53 pmOMA - ECP
1 stop6h 56mUnited Airlines
mié. 12/106:30 amECP - OMA
2 stops9h 52mUnited Airlines
Deal found 11/3$324
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/22:16 pmDSM - ECP
1 stop6h 15mDelta
mar. 12/912:33 pmECP - DSM
1 stop7h 10mDelta
Deal found 11/2$328
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/36:25 amOMA - ECP
2 stops9h 25mSouthwest
mié. 12/107:15 amECP - OMA
2 stops9h 35mSouthwest
Deal found 11/3$329
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/37:00 amOMA - ECP
1 stop5h 47mDelta
lun. 12/84:26 pmECP - OMA
1 stop4h 24mDelta
Deal found 11/3$332
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/411:23 amDSM - ECP
1 stop4h 20mDelta
mar. 12/97:30 amECP - DSM
1 stop6h 01mDelta
Deal found 11/2$337
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/35:00 amOMA - ECP
2 stops11h 47mAmerican Airlines
lun. 12/86:20 amECP - OMA
1 stop8h 19mAmerican Airlines
Deal found 11/2$337
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/21:06 pmDSM - ECP
2 stops10h 09mAmerican Airlines
mar. 12/912:08 pmECP - DSM
2 stops10h 21mAmerican Airlines
Deal found 11/2$338
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/14:03 pmDSM - ECP
1 stop7h 46mAmerican Airlines
dom. 12/76:30 amECP - DSM
1 stop8h 25mAmerican Airlines
Deal found 11/1$362
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/76:00 amCID - ECP
1 stop6h 40mDelta
dom. 11/94:26 pmECP - CID
1 stop6h 12mDelta
Deal found 11/3$369

Cheap flight deals from Iowa to Panama City

Keep the following information in mind while searching for Iowa to Panama City flight deals. Data was last updated noviembre 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$239
(Delta)

One-way from

$157
(United Airlines)

Popular in

March

Cheapest in

August

Average price

$462
Provider with most accurate pricing for Des Moines-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Panama City NW Florida Beaches flights.
Search Deals
From Iowa to Panama City NW Florida Beaches
Search Deals
One-way flight from Iowa to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($76 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 3, 2025.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.

Fly from

Iowa

Fly to

Panama City

Route

Depart

Return

Price

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

mar. 2/3

5:51 am-11:10 am

1 stop5h 19m

Panama City NW Florida Beaches

mié. 2/11

4:45 pm-10:32 pm

1 stop5h 47m

$239

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

mar. 2/3

5:51 am-11:10 am

1 stop5h 19m

Panama City NW Florida Beaches

mar. 2/10

4:45 pm-10:32 pm

1 stop5h 47m

$239

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

mar. 2/3

5:51 am-11:10 am

1 stop5h 19m

Panama City NW Florida Beaches

lun. 2/9

6:09 pm-10:32 pm

1 stop4h 23m

$244

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

mar. 2/3

5:51 am-11:10 am

1 stop5h 19m

Panama City NW Florida Beaches

jue. 2/12

12:15 pm-4:20 pm

1 stop4h 05m

$244

Cedar RapidsPanama City

CID - ECP

CIDECP

Cedar Rapids

sáb. 4/25

12:05 pm-10:41 pm

2 stops10h 36m

Panama City NW Florida Beaches

mié. 4/29

4:10 pm-9:50 pm

1 stop5h 40m

$254

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

mié. 2/4

5:51 am-11:10 am

1 stop5h 19m

Panama City NW Florida Beaches

mar. 2/10

4:45 pm-10:32 pm

1 stop5h 47m

$269

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

mié. 2/4

5:51 am-11:10 am

1 stop5h 19m

Panama City NW Florida Beaches

jue. 2/12

12:15 pm-4:20 pm

1 stop4h 05m

$274

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

mié. 2/4

5:51 am-11:10 am

1 stop5h 19m

Panama City NW Florida Beaches

vie. 2/13

4:04 pm-10:32 pm

1 stop6h 28m

$274

Cedar RapidsPanama City

CID - ECP

CIDECP

Cedar Rapids

mié. 1/7

12:11 pm-7:50 pm

2 stops7h 39m

Panama City NW Florida Beaches

dom. 1/11

5:14 pm-9:51 pm

1 stop4h 37m

$294

Cedar RapidsPanama City

CID - ECP

CIDECP

Cedar Rapids

dom. 11/16

5:54 am-10:26 am

1 stop4h 32m

Panama City NW Florida Beaches

dom. 11/23

4:26 pm-10:38 pm

1 stop6h 12m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 37 results
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Best time to book a flight from Iowa to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama City

What is the cheapest month to book a flight from Iowa to Panama City, Florida?

Currently, July is the cheapest month in which you can book a flight from Iowa to Panama City, Florida (average of $108). Flying from Iowa to Panama City, Florida in December is currently the most expensive (average of $252). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Iowa?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from Iowa to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • How long is the flight from Iowa to Panama City, Florida?

    For as low as $239, Delta can have you in Panama City, Florida from Iowa in 5h 19m. Iowa and Panama City, Florida are separated by a distance of 809 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Iowa to Panama City, Florida one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $157. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Iowa to Panama City, Florida for a low price.

  • What are the most popular routes from Iowa to Panama City, Florida?

    Most travelers choose Des Moines - Panama City NW Florida Beaches, Omaha Eppley Airfield - Panama City NW Florida Beaches or Cedar Rapids - Panama City NW Florida Beaches when deciding on the best route from Iowa to Panama City, Florida.

  • Can I find deals for flights from Iowa to Panama City that include hotel bookings?

    Yes. In addition to deals on Iowa to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama City.

  • Can I find deals for business class flights from Iowa to Panama City?

    Yes. Cheapflights offers flight deals from Iowa to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Panama City, Florida?

    Currently, July is the cheapest month in which you can book a flight from Iowa to Panama City, Florida (average of $108). Flying from Iowa to Panama City, Florida in December is currently the most expensive (average of $252). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Alternative routes for Iowa to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to Panama City

Discover the top 4 airlines that operate flights from Iowa to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$239Average$400FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$391FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$253Average$505FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$302Average$409FlexibilityNo cancel feeOn-time63%

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