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Panama City

$119+ Cheap flights from Iowa to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ECP
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Iowa to Panama City

Keep the following information in mind while searching for Iowa to Panama City flight deals. Data was last updated September 17, 2025.

Round-trip from

$249
(American Airlines)

One-way from

$119
(Southwest)

Popular in

March

Cheapest in

August

Average price

$366
From Iowa to Panama City NW Florida Beaches
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One-way flight from Iowa to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 13% potential increase in price ($70 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Iowa to Panama City

Cheapest flights from Iowa to Panama City
Explore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/115:08 pmMLI - ECP
1 stop5h 29mDelta
Sat 11/155:00 pmECP - MLI
1 stop5h 33mDelta
Deal found 9/15$249
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/115:54 amCID - ECP
1 stop4h 32mDelta
Sat 11/156:00 amECP - CID
2 stops9h 42mDelta
Deal found 9/15$254
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/105:00 amOMA - ECP
1 stop7h 41mAmerican Airlines
Fri 11/146:47 amECP - OMA
1 stop7h 56mAmerican Airlines
Deal found 9/15$257
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:57 amCID - ECP
1 stop3h 58mDelta
Sat 10/45:02 pmECP - CID
1 stop5h 41mDelta
Deal found 9/15$259
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:37 pmOMA - ECP
1 stop4h 33mDelta
Fri 10/106:17 pmECP - OMA
1 stop5h 42mDelta
Deal found 9/15$262
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:30 amCID - ECP
1 stop6h 40mUnited Airlines
Sat 10/46:30 amECP - CID
2 stops10h 24mUnited Airlines
Deal found 9/15$264
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/101:20 pmOMA - ECP
2 stops7h 45mSouthwest
Fri 11/147:30 amECP - OMA
2 stops11h 45mSouthwest
Deal found 9/15$267
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:57 amCID - ECP
1 stop3h 58mDelta
Wed 10/14:46 pmECP - CID
1 stop5h 57mDelta
Deal found 9/16$284
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/274:59 pmMLI - ECP
1 stop6h 04mDelta
Wed 10/14:46 pmECP - MLI
1 stop5h 56mDelta
Deal found 9/16$284
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/115:00 pmMLI - ECP
1 stop5h 41mDelta
Wed 10/155:32 pmECP - MLI
1 stop4h 48mDelta
Deal found 9/15$294
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/45:47 amDSM - ECP
1 stop4h 32mDelta
Tue 11/187:02 amECP - DSM
1 stop6h 30mDelta
Deal found 9/15$297
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:46 amCID - ECP
1 stop4h 29mDelta
Thu 12/2511:00 amECP - CID
2 stops11h 54mDelta
Deal found 9/15$299

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.

Fly from

Iowa

Fly to

Panama City

Route

Depart

Return

Price

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Sat 2/21

4:00 pm-10:42 pm

1 stop6h 42m

Panama City NW Florida Beaches

Sat 2/28

7:45 am-3:15 pm

1 stop7h 30m

$257

Cedar RapidsPanama City

CID - ECP

CIDECP

Cedar Rapids

Tue 9/30

5:57 am-9:55 am

1 stop3h 58m

Panama City NW Florida Beaches

Sat 10/4

5:02 pm-10:43 pm

1 stop5h 41m

$259

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Mon 11/10

4:50 pm-9:05 pm

1 stop4h 15m

Panama City NW Florida Beaches

Fri 11/14

7:30 am-7:15 pm

2 stops11h 45m

$262

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Tue 10/7

6:37 pm-11:10 pm

1 stop4h 33m

Panama City NW Florida Beaches

Fri 10/10

6:17 pm-11:59 pm

1 stop5h 42m

$262

Cedar RapidsPanama City

CID - ECP

CIDECP

Cedar Rapids

Tue 9/30

6:30 am-1:10 pm

1 stop6h 40m

Panama City NW Florida Beaches

Sat 10/4

6:30 am-4:54 pm

2 stops10h 24m

$264

Cedar RapidsPanama City

CID - ECP

CIDECP

Cedar Rapids

Sat 9/27

5:57 am-9:55 am

1 stop3h 58m

Panama City NW Florida Beaches

Wed 10/1

4:46 pm-10:43 pm

1 stop5h 57m

$284

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 9/27

4:59 pm-11:03 pm

1 stop6h 04m

Panama City NW Florida Beaches

Wed 10/1

4:46 pm-10:42 pm

1 stop5h 56m

$284

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Sat 2/21

11:26 am-9:59 pm

2 stops10h 33m

Panama City NW Florida Beaches

Sat 2/28

6:40 am-5:21 pm

2 stops10h 41m

$288

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 10/11

5:00 pm-10:41 pm

1 stop5h 41m

Panama City NW Florida Beaches

Wed 10/15

5:32 pm-10:20 pm

1 stop4h 48m

$294

Des MoinesPanama City

DSM - ECP

DSMECP

Des Moines

Tue 11/4

5:47 am-10:19 am

1 stop4h 32m

Panama City NW Florida Beaches

Tue 11/18

7:02 am-1:32 pm

1 stop6h 30m

$297

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 39 results
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Best time to book a flight from Iowa to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama City

What is the cheapest month to book a flight from Iowa to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Iowa to Panama City, Florida (average of $346). Flying from Iowa to Panama City, Florida in March is currently the most expensive (average of $459). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Iowa?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from Iowa to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • How long is the flight from Iowa to Panama City, Florida?

    For as low as $262, Delta can have you in Panama City, Florida from Iowa in 4h 15m. Iowa and Panama City, Florida are separated by a distance of 942 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Iowa to Panama City, Florida one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $149. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Iowa to Panama City, Florida for a low price.

  • What are the most popular routes from Iowa to Panama City, Florida?

    Most travelers choose Des Moines - Panama City NW Florida Beaches, Cedar Rapids - Panama City NW Florida Beaches or Omaha Eppley Airfield - Panama City NW Florida Beaches when deciding on the best route from Iowa to Panama City, Florida.

  • Can I find deals for flights from Iowa to Panama City that include hotel bookings?

    Yes. In addition to deals on Iowa to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama City.

  • Can I find deals for business class flights from Iowa to Panama City?

    Yes. Cheapflights offers flight deals from Iowa to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Panama City, Florida (average of $346). Flying from Iowa to Panama City, Florida in March is currently the most expensive (average of $459). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Alternative routes for Iowa to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to Panama City

Discover the top 4 airlines that operate flights from Iowa to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$239Average$399FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$253Average$524FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$271Average$392FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$302Average$409FlexibilityNo cancel feeOn-time63%

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