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Panama City

$160+ Cheap flights from Iowa to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ECP
ene. 25 — feb. 11
dom. 1/25
dom. 2/1
1 adult, Economy
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Cheap flight deals from Iowa to Panama City

Cheapest flights from Iowa to Panama City
Explore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 26, 2025.

This United Airlines deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/243:00 pmDSM - ECP
1 stop6h 54mUnited Airlines
mar. 12/306:15 amECP - DSM
1 stop8h 04mUnited Airlines
Deal found 12/23$637
This American Airlines deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/296:20 amMLI - ECP
1 stop5h 50mAmerican Airlines
vie. 1/26:46 amECP - MLI
1 stop8h 05mAmerican Airlines
Deal found 12/23$644
This Southwest deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/246:15 amDSM - ECP
2 stops8h 25mSouthwest
mar. 12/303:30 pmECP - DSM
2 stops7h 40mSouthwest
Deal found 12/23$647
This American Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/263:27 pmCID - ECP
2 stops8h 26mAmerican Airlines
sáb. 1/34:09 pmECP - CID
1 stop7h 49mAmerican Airlines
Deal found 12/24$662
This Delta deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/266:30 pmDSM - ECP
1 stop4h 14mDelta
sáb. 1/36:00 amECP - DSM
1 stop4h 38mDelta
Deal found 12/25$683
This Southwest deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/311:25 pmOMA - ECP
1 stop5h 40mSouthwest
dom. 1/412:50 pmECP - OMA
1 stop6h 25mSouthwest
Deal found 12/22$698
This Southwest deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/266:35 amDSM - ECP
2 stops10h 45mSouthwest
sáb. 1/312:10 pmECP - DSM
2 stops13h 10mSouthwest
Deal found 12/24$703
This American Airlines deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/295:01 amCID - ECP
1 stop7h 09mAmerican Airlines
jue. 1/14:09 pmECP - CID
1 stop7h 49mAmerican Airlines
Deal found 12/23$739
This American Airlines deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/283:27 pmCID - ECP
2 stops8h 26mAmerican Airlines
jue. 1/14:09 pmECP - CID
1 stop7h 49mAmerican Airlines
Deal found 12/23$859
This American Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/262:07 pmDSM - ECP
1 stop20h 34mAmerican Airlines
sáb. 1/36:46 amECP - DSM
1 stop8h 12mAmerican Airlines
Deal found 12/24$987
This United Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/268:00 amDSM - ECP
3 stops25h 17mUnited Airlines
sáb. 1/36:15 amECP - DSM
2 stops30h 27mUnited Airlines
Deal found 12/25$1,810

Find flight deals from Iowa to Panama City

Keep the following information in mind while searching for Iowa to Panama City flight deals. Data was last updated diciembre 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(Delta)

One-way from

$160
(Delta)

Popular in

December

Cheapest in

August

Average price

$734
Provider with most accurate pricing for Des Moines-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Panama City NW Florida Beaches flights.
Search Deals
From Iowa to Panama City NW Florida Beaches
Search Deals
One-way flight from Iowa to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($104 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 26, 2025.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.

Fly from

Iowa

Fly to

Panama City

Route

Depart

Return

Price

Cedar RapidsPanama City

CID - ECP

CIDECP

Cedar Rapids

mar. 4/28

7:00 am-2:08 pm

1 stop7h 08m

Panama City NW Florida Beaches

sáb. 5/2

3:44 pm-10:44 pm

1 stop7h 00m

$269

Cedar RapidsPanama City

CID - ECP

CIDECP

Cedar Rapids

mié. 1/21

5:35 am-11:08 am

1 stop5h 33m

Panama City NW Florida Beaches

mié. 1/28

4:45 pm-9:47 pm

1 stop5h 02m

$269

Cedar RapidsPanama City

CID - ECP

CIDECP

Cedar Rapids

mar. 1/27

5:35 am-11:08 am

1 stop5h 33m

Panama City NW Florida Beaches

sáb. 1/31

4:45 pm-9:21 pm

1 stop4h 36m

$269

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

lun. 1/26

5:11 pm-10:40 pm

1 stop5h 29m

Panama City NW Florida Beaches

sáb. 1/31

4:45 pm-10:33 pm

1 stop5h 48m

$269

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

mié. 1/28

5:11 pm-10:40 pm

1 stop5h 29m

Panama City NW Florida Beaches

mar. 2/3

4:45 pm-10:33 pm

1 stop5h 48m

$269

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

mié. 1/21

5:51 am-11:08 am

1 stop5h 17m

Panama City NW Florida Beaches

mié. 1/28

12:15 pm-4:26 pm

1 stop4h 11m

$269

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

dom. 1/25

5:11 pm-10:40 pm

1 stop5h 29m

Panama City NW Florida Beaches

sáb. 1/31

4:45 pm-10:33 pm

1 stop5h 48m

$269

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

mar. 1/27

5:11 pm-10:40 pm

1 stop5h 29m

Panama City NW Florida Beaches

sáb. 1/31

4:45 pm-10:33 pm

1 stop5h 48m

$269

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

mar. 2/24

8:15 am-7:51 pm

2 stops11h 36m

Panama City NW Florida Beaches

mar. 3/10

2:10 pm-9:59 pm

1 stop7h 49m

$274

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

mié. 1/21

6:15 am-11:33 am

1 stop5h 18m

Panama City NW Florida Beaches

mié. 1/28

12:03 pm-9:58 pm

2 stops9h 55m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/23

Showing 1-10 of 49 results
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Best time to book a flight from Iowa to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama City

What is the cheapest month to book a flight from Iowa to Panama City, Florida?

Currently, July is the cheapest month in which you can book a flight from Iowa to Panama City, Florida (average of $108). Flying from Iowa to Panama City, Florida in March is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Iowa?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from Iowa to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • How long is the flight from Iowa to Panama City, Florida?

    For as low as $269, American Airlines can have you in Panama City, Florida from Iowa in 5h 33m. Iowa and Panama City, Florida are separated by a distance of 861 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Iowa to Panama City, Florida?

    Most travelers choose Moline Quad-City - Panama City NW Florida Beaches, Omaha Eppley Airfield - Panama City NW Florida Beaches or Des Moines - Panama City NW Florida Beaches when deciding on the best route from Iowa to Panama City, Florida.

  • Can I find deals for flights from Iowa to Panama City that include hotel bookings?

    Yes. In addition to deals on Iowa to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama City.

  • Can I find deals for business class flights from Iowa to Panama City?

    Yes. Cheapflights offers flight deals from Iowa to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Panama City, Florida?

    Currently, July is the cheapest month in which you can book a flight from Iowa to Panama City, Florida (average of $108). Flying from Iowa to Panama City, Florida in March is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Alternative routes for Iowa to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to Panama City

Discover the top 4 airlines that operate flights from Iowa to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$239Average$404FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$385FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$253Average$528FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$302Average$396FlexibilityNo cancel feeOn-time63%

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