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Panama City

$119+ Cheap flights from Iowa to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ECP
Aug 6 — Aug 131
Wed 8/6
Wed 8/13
1 adult, Economy
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Cheap flight deals from Iowa to Panama City

Keep the following information in mind while searching for Iowa to Panama City flight deals. Data was last updated August 1, 2025.

Round-trip from

$237
(Delta)

One-way from

$119
(Delta)

Popular in

December

Cheapest in

September

Average price

$348
From Iowa to Panama City NW Florida Beaches
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One-way flight from Iowa to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 10% potential increase in price ($48 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Iowa to Panama City

Cheapest flights from Iowa to Panama City
Explore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2025.

This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:44 amDSM - ECP
1 stop4h 11mDelta
Sat 9/205:02 pmECP - DSM
1 stop5h 35mDelta
Deal found 7/30$237
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/206:15 pmOMA - ECP
1 stop4h 51mDelta
Sat 8/236:59 pmECP - OMA
1 stop5h 06mDelta
Deal found 7/30$237
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:00 amOMA - ECP
2 stops11h 36mAmerican Airlines
Sat 9/206:06 pmECP - OMA
1 stop5h 06mAmerican Airlines
Deal found 7/30$242
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/231:09 pmDSM - ECP
2 stops10h 32mAmerican Airlines
Tue 8/2610:18 amECP - DSM
2 stops11h 27mAmerican Airlines
Deal found 8/1$247
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:57 amCID - ECP
1 stop3h 58mDelta
Wed 9/174:46 pmECP - CID
1 stop5h 57mDelta
Deal found 7/31$249
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:57 amMLI - ECP
1 stop3h 58mDelta
Wed 10/14:46 pmECP - MLI
1 stop5h 56mDelta
Deal found 7/31$249
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/315:08 amCID - ECP
2 stops8h 55mAmerican Airlines
Sun 9/76:59 pmECP - CID
1 stop5h 00mAmerican Airlines
Deal found 8/1$279
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/138:35 amDSM - ECP
2 stops10h 35mSouthwest
Sat 9/202:15 pmECP - DSM
1 stop6h 05mSouthwest
Deal found 7/29$286
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/221:10 pmOMA - ECP
2 stops8h 15mSouthwest
Mon 8/251:35 pmECP - OMA
1 stop4h 05mSouthwest
Deal found 7/31$297
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/206:00 amOMA - ECP
1 stop7h 52mUnited Airlines
Tue 8/266:30 amECP - OMA
2 stops9h 48mUnited Airlines
Deal found 7/30$312
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/276:30 amMLI - ECP
2 stops9h 46mUnited Airlines
Wed 10/11:55 pmECP - MLI
1 stop7h 10mUnited Airlines
Deal found 7/30$324
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/168:05 amCID - ECP
1 stop5h 18mUnited Airlines
Wed 8/201:44 pmECP - CID
1 stop7h 41mUnited Airlines
Deal found 8/1$329

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2025.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.

Fly from

Iowa

Fly to

Panama City

Route

Depart

Return

Price

Des MoinesPanama City

DSM - ECP

DSMECP

Des Moines

Sat 9/13

5:44 am-9:55 am

1 stop4h 11m

Panama City NW Florida Beaches

Sat 9/20

5:02 pm-10:37 pm

1 stop5h 35m

$237

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Wed 8/20

2:55 pm-7:48 pm

1 stop4h 53m

Panama City NW Florida Beaches

Tue 8/26

9:24 am-3:17 pm

1 stop5h 53m

$237

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Wed 9/17

6:00 am-5:36 pm

2 stops11h 36m

Panama City NW Florida Beaches

Sat 9/20

6:06 pm-11:12 pm

1 stop5h 06m

$242

Des MoinesPanama City

DSM - ECP

DSMECP

Des Moines

Sat 8/23

1:09 pm-11:41 pm

2 stops10h 32m

Panama City NW Florida Beaches

Tue 8/26

10:18 am-9:45 pm

2 stops11h 27m

$247

Cedar RapidsPanama City

CID - ECP

CIDECP

Cedar Rapids

Sat 9/13

5:57 am-9:55 am

1 stop3h 58m

Panama City NW Florida Beaches

Wed 9/17

4:46 pm-10:43 pm

1 stop5h 57m

$249

MolinePanama City

MLI - ECP

MLIECP

Moline Quad-City

Sat 9/27

5:57 am-9:55 am

1 stop3h 58m

Panama City NW Florida Beaches

Wed 10/1

4:46 pm-10:42 pm

1 stop5h 56m

$249

Cedar RapidsPanama City

CID - ECP

CIDECP

Cedar Rapids

Sun 8/31

5:08 am-2:03 pm

2 stops8h 55m

Panama City NW Florida Beaches

Sun 9/7

6:59 pm-11:59 pm

1 stop5h 00m

$279

Des MoinesPanama City

DSM - ECP

DSMECP

Des Moines

Sat 9/13

8:35 am-7:10 pm

2 stops10h 35m

Panama City NW Florida Beaches

Sat 9/20

2:15 pm-8:20 pm

1 stop6h 05m

$286

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Fri 8/22

1:10 pm-9:25 pm

2 stops8h 15m

Panama City NW Florida Beaches

Mon 8/25

1:35 pm-5:40 pm

1 stop4h 05m

$297

OmahaPanama City

OMA - ECP

OMAECP

Omaha Eppley Airfield

Wed 8/20

6:00 am-1:52 pm

1 stop7h 52m

Panama City NW Florida Beaches

Tue 8/26

6:30 am-4:18 pm

2 stops9h 48m

$312

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 25 results
1
2
3

Best time to book a flight from Iowa to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama City

What is the cheapest month to book a flight from Iowa to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Iowa to Panama City, Florida (average of $346). Flying from Iowa to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 1, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Iowa to Panama City have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,983 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,904 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Iowa?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from Iowa to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • What are the cheapest airlines to fly from Iowa to Panama City, Florida one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $119. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Iowa to Panama City, Florida for a low price.

  • What are the most popular routes from Iowa to Panama City, Florida?

    Most travelers choose Omaha Eppley Airfield - Panama City NW Florida Beaches, Cedar Rapids - Panama City NW Florida Beaches or Des Moines - Panama City NW Florida Beaches when deciding on the best route from Iowa to Panama City, Florida.

  • Can I find deals for flights from Iowa to Panama City that include hotel bookings?

    Yes. In addition to deals on Iowa to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama City.

  • Can I find deals for business class flights from Iowa to Panama City?

    Yes. Cheapflights offers flight deals from Iowa to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Panama City, Florida (average of $346). Flying from Iowa to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Alternative routes for Iowa to Panama City

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Top 4 airlines flying from Iowa to Panama City

Discover the top 4 airlines that operate flights from Iowa to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$395FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$376FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$253Average$473FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$351Average$426FlexibilityNo cancel feeOn-time63%

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