$126+ Cheap flights from Knoxville to Myrtle Beach (TYS - MYR)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MYR
apr. 27 — mai 41
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Myrtle Beach with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Myrtle Beach
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to Myrtle BeachExplore the most affordable flight options available from Knoxville to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mars 28, 2026.
Explore the most affordable flight options available from Knoxville to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mars 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to. 4/169:32 pm
TYS
- MYR
1 stop25h 57m
Multiple Airlines
to. 4/2311:52 am
MYR
- TYS
1 stop8h 50m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 5/134:25 pm
TYS
- MYR
1 stop28h 11m
Multiple Airlines
on. 5/203:17 pm
MYR
- TYS
1 stop23h 39m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 4/294:25 pm
TYS
- MYR
1 stop15h 46m
Multiple Airlines
fr. 5/16:55 pm
MYR
- TYS
1 stop18h 14m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma. 6/11:36 pm
TYS
- MYR
1 stop7h 22m
Multiple Airlines
fr. 6/52:28 pm
MYR
- TYS
1 stop9h 11m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fr. 4/247:10 am
TYS
- MYR
1 stop25h 34m
Multiple Airlines
ma. 4/273:20 pm
MYR
- TYS
1 stop18h 20m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti. 4/72:56 pm
TYS
- MYR
1 stop26h 37m
Multiple Airlines
lø. 4/113:29 pm
MYR
- TYS
1 stop20h 06m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma. 4/207:30 am
TYS
- MYR
1 stop15h 59m
Multiple Airlines
ma. 4/278:43 pm
MYR
- TYS
2 stops37h 53m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to. 4/163:35 pm
TYS
- MYR
1 stop7h 54m
Multiple Airlines
sø. 4/199:18 am
MYR
- TYS
2 stops12h 39m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$308
Best flights from Knoxville to Myrtle BeachDiscover carefully curated flight deals from Knoxville to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated mars 28, 2026.
Discover carefully curated flight deals from Knoxville to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated mars 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti. 4/72:56 pm
TYS
- MYR
1 stop26h 37m
Multiple Airlines
lø. 4/113:29 pm
MYR
- TYS
1 stop20h 06m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 5/137:05 am
TYS
- MYR
2 stops8h 20m
Southwest
on. 5/207:35 am
MYR
- TYS
2 stops12h 05m
Southwest
Deal found 3/27![Southwest logo]()
$315
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 6/37:33 pm
TYS
- MYR
1 stop4h 25m
Delta
on. 6/107:54 pm
MYR
- TYS
1 stop4h 00m
Delta
Deal found 3/25![Delta logo]()
$340
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 4/228:15 am
TYS
- MYR
1 stop7h 10m
Southwest
fr. 4/243:45 pm
MYR
- TYS
1 stop4h 35m
Southwest
Deal found 3/24![Southwest logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti. 3/313:00 pm
TYS
- MYR
1 stop26h 33m
Multiple Airlines
to. 4/210:27 am
MYR
- TYS
1 stop27h 02m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$407
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma. 4/206:35 am
TYS
- MYR
2 stops14h 15m
Southwest
ma. 4/271:45 pm
MYR
- TYS
2 stops6h 35m
Southwest
Deal found 3/23![Southwest logo]()
$373
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to. 4/166:35 am
TYS
- MYR
2 stops14h 15m
Southwest
to. 4/238:30 am
MYR
- TYS
2 stops11h 50m
Southwest
Deal found 3/24![Southwest logo]()
$445
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti. 4/77:05 am
TYS
- MYR
2 stops8h 20m
Southwest
lø. 4/117:10 am
MYR
- TYS
2 stops11h 20m
Southwest
Deal found 3/23![Southwest logo]()
$453
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sø. 6/217:05 am
TYS
- MYR
2 stops10h 05m
Southwest
to. 6/252:00 pm
MYR
- TYS
2 stops7h 10m
Southwest
Deal found 3/25![Southwest logo]()
$462
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 4/87:05 am
TYS
- MYR
2 stops8h 20m
Southwest
ma. 4/131:45 pm
MYR
- TYS
2 stops6h 35m
Southwest
Deal found 3/27![Southwest logo]()
$466
Last-minute flights from Knoxville to Myrtle BeachDiscover last-minute flight deals from Knoxville to Myrtle Beach. Data last updated mars 28, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Myrtle Beach. Data last updated mars 28, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma. 3/303:29 pm
TYS
- MYR
1 stop19h 36m
Multiple Airlines
on. 4/16:28 pm
MYR
- TYS
1 stop26h 28m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti. 4/72:56 pm
TYS
- MYR
1 stop26h 37m
Multiple Airlines
lø. 4/113:29 pm
MYR
- TYS
1 stop20h 06m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 4/154:25 pm
TYS
- MYR
2 stops16h 05m
Multiple Airlines
to. 4/1611:52 am
MYR
- TYS
1 stop8h 50m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to. 4/169:32 pm
TYS
- MYR
1 stop25h 57m
Multiple Airlines
to. 4/2311:52 am
MYR
- TYS
1 stop8h 50m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to. 4/163:35 pm
TYS
- MYR
1 stop7h 54m
Multiple Airlines
sø. 4/199:18 am
MYR
- TYS
2 stops12h 39m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma. 4/207:30 am
TYS
- MYR
1 stop15h 59m
Multiple Airlines
ma. 4/278:43 pm
MYR
- TYS
2 stops37h 53m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fr. 4/247:10 am
TYS
- MYR
1 stop25h 34m
Multiple Airlines
ma. 4/273:20 pm
MYR
- TYS
1 stop18h 20m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 4/294:25 pm
TYS
- MYR
1 stop15h 46m
Multiple Airlines
fr. 5/16:55 pm
MYR
- TYS
1 stop18h 14m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$270
One-way flights from Knoxville to Myrtle BeachSearch for one-way flight options from Knoxville to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated mars 28, 2026.
Search for one-way flight options from Knoxville to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated mars 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma. 4/277:30 am
TYS
- MYR
1 stop15h 59m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 4/18:30 am
TYS
- MYR
1 stop26h 35m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$173
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lø. 5/237:45 am
TYS
- MYR
1 stop8h 25m
Southwest
Deal found 3/25![Southwest logo]()
$174
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fr. 4/105:00 am
TYS
- MYR
1 stop3h 24m
American Airlines
Deal found 3/27![American Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fr. 4/106:35 am
TYS
- MYR
2 stops14h 15m
Southwest
Deal found 3/27![Southwest logo]()
$230
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 4/16:35 am
TYS
- MYR
2 stops10h 10m
Southwest
Deal found 3/26![Southwest logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fr. 4/101:15 pm
TYS
- MYR
3 stops25h 17m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$371
Find flight deals from Knoxville to Myrtle Beach
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated mars 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $226 (Kiwi.com) |
One-way from | $126 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $477 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mars 28, 2026.
Use the filters below to find and compare flights from Knoxville to Myrtle Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
ti. 4/7
2:56 pm-5:33 pm
1 stop26h 37m
Myrtle Beach Intl
lø. 4/11
3:29 pm-11:35 am
1 stop20h 06m
$293
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
on. 5/13
7:05 am-3:25 pm
2 stops8h 20m
Myrtle Beach Intl
on. 5/20
7:35 am-7:40 pm
2 stops12h 05m
$315
Quickest round-trip
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
on. 6/3
7:33 pm-11:58 pm
1 stop4h 25m
Myrtle Beach Intl
on. 6/10
7:54 pm-11:54 pm
1 stop4h 00m
$340
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
on. 4/22
8:15 am-3:25 pm
1 stop7h 10m
Myrtle Beach Intl
fr. 4/24
3:45 pm-8:20 pm
1 stop4h 35m
$357
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
ma. 4/20
6:35 am-8:50 pm
2 stops14h 15m
Myrtle Beach Intl
ma. 4/27
1:45 pm-8:20 pm
2 stops6h 35m
$373
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
ti. 3/31
3:00 pm-5:33 pm
1 stop26h 33m
Myrtle Beach Intl
to. 4/2
10:27 am-1:29 pm
1 stop27h 02m
$407
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
to. 4/16
6:35 am-8:50 pm
2 stops14h 15m
Myrtle Beach Intl
to. 4/23
8:30 am-8:20 pm
2 stops11h 50m
$445
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
ti. 4/7
7:05 am-3:25 pm
2 stops8h 20m
Myrtle Beach Intl
lø. 4/11
7:10 am-6:30 pm
2 stops11h 20m
$453
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
sø. 6/21
7:05 am-5:10 pm
2 stops10h 05m
Myrtle Beach Intl
to. 6/25
2:00 pm-9:10 pm
2 stops7h 10m
$462
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
on. 4/8
7:05 am-3:25 pm
2 stops8h 20m
Myrtle Beach Intl
ma. 4/13
1:45 pm-8:20 pm
2 stops6h 35m
$466
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Myrtle Beach
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Myrtle Beach in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Myrtle Beach flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Myrtle Beach flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Myrtle Beach flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Myrtle Beach flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Myrtle Beach
Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Knoxville with our price prediction graph.
TYS-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Myrtle Beach
What is the cheapest month to book a flight from Knoxville to Myrtle Beach?
Currently, June is the cheapest month in which you can book a flight from Knoxville to Myrtle Beach (average of $168). Flying from Knoxville to Myrtle Beach in February is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Myrtle Beach?
Reviews of airlines servicing Myrtle Beach
Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated mars 28, 2026.
Read through reviews of airlines operating flights from Knoxville to Myrtle Beach, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Entertainment
7.8
Overall
7.9
Boarding
8.1
Crew
8.5
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Entertainment
7.8
Overall
7.9
Boarding
8.1
Crew
8.5
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Entertainment
7.8
Overall
7.9
Boarding
8.1
Crew
8.5
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Myrtle Beach?
Book flights to Myrtle Beach if you plan to visit one of these locationsConway
Surfside Beach
Pawleys Island
Little River
Garden City Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Myrtle Beach flight routes
Other flight options
Other flights from Knoxville
Popular flights
Alternative routes for Knoxville to Myrtle Beach
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Myrtle Beach by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Myrtle Beach by cabin class
Find flights from Knoxville to Myrtle Beach, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Myrtle Beach
Explore flights to Myrtle Beach departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on mars 28, 2026.
Knoxville and Myrtle Beach flights
Browse other Knoxville and Myrtle Beach flight options. Last updated on mars 28, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on mars 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Knoxville to Myrtle Beach
Discover the top 2 airlines that operate flights from Knoxville to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mars 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$125 | Average$422 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$314 | FlexibilityNo cancel fee | On-time71% |