How long is the flight from Des Moines to Myrtle Beach?

There are many flights that can get you from Des Moines to Myrtle Beach in 7h 40m. Fly via American Airlines or Delta to get the fastest option. Des Moines and Myrtle Beach are separated by a distance of 969 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Des Moines to Myrtle Beach round-trip?

Our cheapest airline available from Des Moines to Myrtle Beach is American Airlines. Our recent data shows that you can find tickets from as low as $248 on this airline. Additional options worth looking into are Southwest and Delta, starting at $272 and $292 round-trip. American Airlines is currently priced 35% below the average price you’ll pay for this route.

In terms of precipitation, rainfall in Myrtle Beach ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit Myrtle Beach when rainfall is around 3.0 in.

If weather is an important factor for your trip to Myrtle Beach, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

What are the most popular airlines that fly from Des Moines to Myrtle Beach?

When booking a flight from Des Moines to Myrtle Beach, you may want to consider flying on American Airlines, Delta or Southwest as they are the most popular for this route.

What is the cheapest time of day to fly from DSM to MYR?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Myrtle Beach as you normally would.

Most accurate provider : When it comes to deals on Des Moines-Myrtle Beach flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Myrtle Beach flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Myrtle Beach flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Des Moines-Myrtle Beach flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Des Moines to Myrtle Beach that include hotel bookings?

Yes. In addition to deals on Des Moines to Myrtle Beach flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Myrtle Beach?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Myrtle Beach.

Can I find deals for business class flights from Des Moines to Myrtle Beach?

Yes. Cheapflights offers flight deals from Des Moines to Myrtle Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$289+ Flights from Des Moines to Myrtle Beach

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Find cheap flights from Des Moines to Myrtle Beach with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Des Moines to Myrtle Beach Intl are usually found in August or April, booked 40 days in advance, depart on a Tuesday or Wednesday and return on a Monday

Cheap flight deals from Des Moines to Myrtle Beach

Cheapest flights from Des Moines to Myrtle Beach
Explore the most affordable flight options available from Des Moines to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Sat 12/201:56 pmDSM - MYR

1 stop4h 15mAmerican Airlines

Wed 12/3112:48 pmMYR - DSM

1 stop6h 33mAmerican Airlines

Deal found 12/11

$483

Sun 12/142:56 pmDSM - MYR

1 stop25h 52mMultiple Airlines

Tue 12/166:36 pmMYR - DSM

2 stops44h 30mMultiple Airlines

Deal found 12/10

$635

Mon 12/156:33 pmDSM - MYR

1 stop4h 10mDelta

Thu 12/1812:30 pmMYR - DSM

1 stop8h 13mDelta

Deal found 12/10

$687

Mon 12/156:33 pmDSM - MYR

1 stop4h 10mDelta

Wed 12/1712:30 pmMYR - DSM

1 stop8h 13mDelta

Deal found 12/11

$747

Best flights from Des Moines to Myrtle Beach
Discover carefully curated flight deals from Des Moines to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Sun 1/254:30 pmDSM - MYR

3 stops25h 50mMultiple Airlines

Sun 2/18:15 pmMYR - DSM

2 stops15h 04mMultiple Airlines

Deal found 12/10

$289

Wed 2/111:16 pmDSM - MYR

2 stops9h 41mAmerican Airlines

Wed 2/186:52 amMYR - DSM

1 stop7h 15mAmerican Airlines

Deal found 12/11

$298

Sat 1/246:24 amDSM - MYR

2 stops7h 40mDelta

Sat 1/316:00 amMYR - DSM

1 stop7h 15mDelta

Deal found 12/10

$322

Sat 4/118:00 amDSM - MYR

1 stop5h 37mUnited Airlines

Sat 4/183:25 pmMYR - DSM

1 stop7h 27mUnited Airlines

Deal found 12/10

$387

Sat 1/246:00 amDSM - MYR

1 stop4h 50mAmerican Airlines

Sat 1/315:44 pmMYR - DSM

1 stop6h 39mAmerican Airlines

Deal found 12/10

$330

Sun 1/255:16 pmDSM - MYR

1 stop5h 25mDelta

Sun 2/16:54 pmMYR - DSM

1 stop4h 35mDelta

Deal found 12/10

$353

Fri 1/2311:09 amDSM - MYR

3 stops26h 33mMultiple Airlines

Sun 1/258:15 pmMYR - DSM

2 stops15h 04mMultiple Airlines

Deal found 12/10

$381

Fri 1/234:25 pmDSM - MYR

1 stop5h 50mAmerican Airlines

Sun 1/255:44 pmMYR - DSM

1 stop6h 39mAmerican Airlines

Deal found 12/10

$387

Last-minute flights from Des Moines to Myrtle Beach
Discover last-minute flight deals from Des Moines to Myrtle Beach. Data last updated December 12, 2025 and is based on user searches.

Fri 1/2311:09 amDSM - MYR

3 stops26h 33mMultiple Airlines

Sun 1/258:15 pmMYR - DSM

2 stops15h 04mMultiple Airlines

Deal found 12/11

$381

Fri 1/2311:26 amDSM - MYR

1 stop5h 33mDelta

Sun 1/2512:40 pmMYR - DSM

1 stop7h 54mDelta

Deal found 12/11

$387

Fri 1/231:16 pmDSM - MYR

2 stops8h 59mAmerican Airlines

Sun 1/256:23 amMYR - DSM

2 stops11h 01mAmerican Airlines

Deal found 12/11

$397

Sat 1/246:24 amDSM - MYR

2 stops7h 40mDelta

Sat 1/316:00 amMYR - DSM

1 stop7h 15mDelta

Deal found 12/10

$322

Sat 1/246:00 amDSM - MYR

1 stop4h 50mAmerican Airlines

Sat 1/315:44 pmMYR - DSM

1 stop6h 39mAmerican Airlines

Deal found 12/10

$330

Sun 1/254:30 pmDSM - MYR

3 stops25h 50mMultiple Airlines

Sun 2/18:15 pmMYR - DSM

2 stops15h 04mMultiple Airlines

Deal found 12/10

$289

Sun 1/255:16 pmDSM - MYR

1 stop5h 25mDelta

Sun 2/16:54 pmMYR - DSM

1 stop4h 35mDelta

Deal found 12/10

$353

One-way flights from Des Moines to Myrtle Beach
Search for one-way flight options from Des Moines to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Sat 12/207:35 amDSM - MYR

1 stop15h 24mMultiple Airlines

Deal found 12/10

$292

Find flight deals from Des Moines to Myrtle Beach

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$289 (Mytrip)
Popular in	June
Cheapest in	August
Average price	$373

Provider with most accurate pricing for Des Moines-Myrtle Beach Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Myrtle Beach Intl flights.

Search Deals

From Des Moines to Myrtle Beach Intl

Search Deals

Highest demand for flights based on searches. 9% potential increase in price ($39 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Myrtle Beach that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sun 1/25

4:30 pm-7:20 pm

3 stops25h 50m

Myrtle Beach Intl

Sun 2/1

8:15 pm-10:19 am

2 stops15h 04m

$289

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Wed 2/11

1:16 pm-11:57 pm

2 stops9h 41m

Myrtle Beach Intl

Wed 2/18

6:52 am-1:07 pm

1 stop7h 15m

$298

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 1/24

6:24 am-3:04 pm

2 stops7h 40m

Myrtle Beach Intl

Sat 1/31

6:00 am-12:15 pm

1 stop7h 15m

$322

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 1/24

6:00 am-11:50 am

1 stop4h 50m

Myrtle Beach Intl

Sat 1/31

5:44 pm-11:23 pm

1 stop6h 39m

$330

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sun 1/25

5:16 pm-11:41 pm

1 stop5h 25m

Myrtle Beach Intl

Sun 2/1

6:54 pm-10:29 pm

1 stop4h 35m

$353

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Fri 1/23

11:09 am-2:42 pm

3 stops26h 33m

Myrtle Beach Intl

Sun 1/25

8:15 pm-10:19 am

2 stops15h 04m

$381

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 4/11

8:00 am-2:37 pm

1 stop5h 37m

Myrtle Beach Intl

Sat 4/18

3:25 pm-9:52 pm

1 stop7h 27m

$387

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Fri 1/23

4:25 pm-11:15 pm

1 stop5h 50m

Myrtle Beach Intl

Sun 1/25

5:44 pm-11:23 pm

1 stop6h 39m

$387

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 12/20

7:35 am-11:59 pm

1 stop15h 24m

$292

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Compare providers for flights from Des Moines to Myrtle Beach

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Myrtle Beach in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Des Moines-Myrtle Beach flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Myrtle Beach flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Myrtle Beach flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Des Moines-Myrtle Beach flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Myrtle Beach

Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Myrtle Beach

How far ahead should I book a flight from Des Moines to Myrtle Beach?

The price you pay for your flight from Des Moines to Myrtle Beach may vary depending on when you book. For the best chance of a lower fare, look to book 40 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Myrtle Beach?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Myrtle Beach (average of $166). Flying from Des Moines to Myrtle Beach in February is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Myrtle Beach

See what other customers who have flown with Southwest, Delta, and United Airlines from Des Moines to Myrtle Beach have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,253 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,008 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,095 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,050 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How long is the flight from Des Moines to Myrtle Beach?
There are many flights that can get you from Des Moines to Myrtle Beach in 7h 40m. Fly via American Airlines or Delta to get the fastest option. Des Moines and Myrtle Beach are separated by a distance of 969 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Des Moines to Myrtle Beach round-trip?
Our cheapest airline available from Des Moines to Myrtle Beach is American Airlines. Our recent data shows that you can find tickets from as low as $248 on this airline. Additional options worth looking into are Southwest and Delta, starting at $272 and $292 round-trip. American Airlines is currently priced 35% below the average price you’ll pay for this route.
Can I find deals for flights from Des Moines to Myrtle Beach that include hotel bookings?
Yes. In addition to deals on Des Moines to Myrtle Beach flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Myrtle Beach?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Myrtle Beach.
Can I find deals for business class flights from Des Moines to Myrtle Beach?
Yes. Cheapflights offers flight deals from Des Moines to Myrtle Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Myrtle Beach?
Currently, May is the cheapest month in which you can book a flight from Des Moines to Myrtle Beach (average of $166). Flying from Des Moines to Myrtle Beach in February is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Complete your trip

Myrtle Beach car rentals

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Other flights to Myrtle Beach

Top 4 airlines flying from Des Moines to Myrtle Beach

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$248	Average$366	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$272	Average$404	FlexibilityNo cancel fee	On-time63%
Delta	Cheapest$292	Average$369	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$366	Average$436	FlexibilityNo cancel fee	On-time69%

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$289+ Cheap flights from Des Moines to Myrtle Beach (DSM - MYR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Myrtle Beach with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Des Moines to Myrtle Beach Intl are usually found in August or April, booked 40 days in advance, depart on a Tuesday or Wednesday and return on a Monday

Cheap flight deals from Des Moines to Myrtle Beach

Cheapest flights from Des Moines to Myrtle BeachExplore the most affordable flight options available from Des Moines to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from Des Moines to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from Des Moines to Myrtle Beach

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Myrtle Beach that are best for you.

Compare providers for flights from Des Moines to Myrtle Beach

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Myrtle Beach in December.

Best time to book a flight from Des Moines to Myrtle Beach

Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Myrtle Beach

How far ahead should I book a flight from Des Moines to Myrtle Beach?

What is the cheapest month to book a flight from Des Moines to Myrtle Beach?

Reviews of airlines servicing Myrtle Beach

See what other customers who have flown with Southwest, Delta, and United Airlines from Des Moines to Myrtle Beach have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Des Moines to Myrtle Beach?

What are the cheapest airlines flying from Des Moines to Myrtle Beach round-trip?

Can I find deals for flights from Des Moines to Myrtle Beach that include hotel bookings?

How can I find direct flights from Des Moines to Myrtle Beach?

Can I find deals for business class flights from Des Moines to Myrtle Beach?

What is the cheapest month to book a flight from Des Moines to Myrtle Beach?

Traveling to a place near Myrtle Beach?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Myrtle Beach

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Des Moines to Myrtle Beach

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Cheapest flights from Des Moines to Myrtle Beach
Explore the most affordable flight options available from Des Moines to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.