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Myrtle Beach

$219+ Cheap flights from Des Moines to Myrtle Beach (DSM - MYR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MYR
oct. 11 — oct. 181
sam. 10/11
sam. 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Myrtle Beach Intl are usually found in August or April, booked 40 days in advance, depart on a Tuesday or Wednesday and return on a Monday

Cheap flight deals from Des Moines to Myrtle Beach

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septembre 11, 2025.

Round-trip from

$219
(American Airlines)

Popular in

June

Cheapest in

August

Average price

$348
From Des Moines to Myrtle Beach Intl
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($28 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Myrtle Beach

Cheapest flights from Des Moines to Myrtle Beach
Explore the most affordable flight options available from Des Moines to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septembre 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/73:48 pmDSM - MYR
1 stop5h 48mAmerican Airlines
mar. 10/214:47 pmMYR - DSM
1 stop7h 29mAmerican Airlines
Deal found 9/10$219
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/712:49 pmDSM - MYR
2 stops9h 05mAmerican Airlines
mar. 10/147:26 pmMYR - DSM
1 stop5h 33mAmerican Airlines
Deal found 9/9$224
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 10/45:38 pmDSM - MYR
1 stop4h 30mAmerican Airlines
sam. 10/114:47 pmMYR - DSM
1 stop7h 29mAmerican Airlines
Deal found 9/11$262
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 11/123:18 pmDSM - MYR
1 stop6h 18mAmerican Airlines
dim. 11/168:07 pmMYR - DSM
1 stop5h 14mAmerican Airlines
Deal found 9/11$286
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 10/257:25 amDSM - MYR
2 stops10h 20mSouthwest
lun. 10/275:50 pmMYR - DSM
2 stops6h 40mSouthwest
Deal found 9/10$319
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 11/62:16 pmDSM - MYR
1 stop6h 49mAmerican Airlines
dim. 11/98:07 pmMYR - DSM
1 stop5h 14mAmerican Airlines
Deal found 9/11$329
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 9/264:09 pmDSM - MYR
1 stop5h 42mAmerican Airlines
mar. 9/305:52 pmMYR - DSM
1 stop6h 21mAmerican Airlines
Deal found 9/11$333

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 11, 2025.
Use the filters below to find and compare flights from Des Moines to Myrtle Beach that are best for you.

Fly from

Des Moines

Fly to

Myrtle Beach

Route

Depart

Return

Price

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

mar. 10/7

5:42 pm-10:54 pm

1 stop4h 12m

Myrtle Beach Intl

mar. 10/14

4:47 pm-11:16 pm

1 stop7h 29m

$219

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

mar. 10/7

6:07 am-11:56 am

1 stop4h 49m

Myrtle Beach Intl

mar. 10/21

12:18 pm-5:02 pm

1 stop5h 44m

$219

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

sam. 10/4

5:38 pm-11:08 pm

1 stop4h 30m

Myrtle Beach Intl

sam. 10/11

4:47 pm-11:16 pm

1 stop7h 29m

$262

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

sam. 10/25

1:55 pm-11:59 pm

2 stops9h 04m

Myrtle Beach Intl

lun. 10/27

7:26 pm-11:59 pm

1 stop5h 33m

$267

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

mer. 11/12

3:18 pm-10:36 pm

1 stop6h 18m

Myrtle Beach Intl

dim. 11/16

8:07 pm-12:21 am

1 stop5h 14m

$286

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

sam. 10/25

7:25 am-6:45 pm

2 stops10h 20m

Myrtle Beach Intl

lun. 10/27

5:50 pm-11:30 pm

2 stops6h 40m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Des Moines to Myrtle Beach

Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Myrtle Beach

How far ahead should I book a flight from Des Moines to Myrtle Beach?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Myrtle Beach. Price data was last updated on August 29, 2025.

The price you pay for your flight from Des Moines to Myrtle Beach may vary depending on when you book. For the best chance of a lower fare, look to book 40 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Myrtle Beach?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Myrtle Beach (average of $196). Flying from Des Moines to Myrtle Beach in March is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MYR?

Find hourly flight availability from Des Moines to Myrtle Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septembre 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to Myrtle Beach in the afternoon. If you’re flexible enough to do this you can expect to save up to 10% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Myrtle Beach

Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated septembre 11, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Des Moines to Myrtle Beach have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,937 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Myrtle Beach?

    There are many flights that can get you from Des Moines to Myrtle Beach in 4h 12m. Fly via American Airlines to get the fastest option. Des Moines and Myrtle Beach are separated by a distance of 969 mi.

  • What are the cheapest airlines flying from Des Moines to Myrtle Beach round-trip?

    Our cheapest airline available from Des Moines to Myrtle Beach is American Airlines. Our recent data shows that you can find tickets from as low as $248 on this airline. Additional options worth looking into are Southwest and Delta, starting at $272 and $296 round-trip. American Airlines is currently priced 37% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Myrtle Beach that include hotel bookings?

    Yes. In addition to deals on Des Moines to Myrtle Beach flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Myrtle Beach?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Myrtle Beach.

  • Can I find deals for business class flights from Des Moines to Myrtle Beach?

    Yes. Cheapflights offers flight deals from Des Moines to Myrtle Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Myrtle Beach?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Myrtle Beach (average of $196). Flying from Des Moines to Myrtle Beach in March is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
Conway
Surfside Beach
Little River
Pawleys Island
Ocean Isle Beach
Garden City Beach

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Top 4 airlines flying from Des Moines to Myrtle Beach

Discover the top 4 airlines that operate flights from Des Moines to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$390FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$272Average$404FlexibilityNo cancel feeOn-time63%
DeltaCheapest$296Average$376FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$366Average$436FlexibilityNo cancel feeOn-time69%

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