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Myrtle Beach

$136+ Cheap flights from Des Moines to Myrtle Beach (DSM - MYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MYR
Touko 4 — Touko 111
su 5/4
su 5/11
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Myrtle Beach Intl are usually found in September or April, booked 66 days in advance, depart on a Tuesday or Wednesday and return on a Monday

Cheap flight deals from Des Moines to Myrtle Beach

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated huhtikuu 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$275
(Mytrip)

One-way from

$136
(Delta)

Popular in

December

Cheapest in

September

Average price

$316
Provider with most accurate pricing for Des Moines-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Myrtle Beach Intl flights.
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From Des Moines to Myrtle Beach Intl
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One-way flight from Des Moines to Myrtle Beach Intl
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Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Des Moines to Myrtle Beach

Cheapest flights from Des Moines to Myrtle Beach
Explore the most affordable flight options available from Des Moines to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on huhtikuu 29, 2025.

This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 9/26:30 pmDSM - MYR
1 stop4h 09mDelta
ti 9/92:15 pmMYR - DSM
1 stop4h 24mDelta
Deal found 4/28$271
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
la 6/71:15 pmDSM - MYR
2 stops28h 15mMultiple Airlines
ke 6/116:00 amMYR - DSM
1 stop8h 33mMultiple Airlines
Deal found 4/29$275
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
la 5/2412:48 pmDSM - MYR
2 stops8h 43mAmerican Airlines
la 5/315:45 pmMYR - DSM
1 stop4h 53mAmerican Airlines
Deal found 4/28$289
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
su 6/226:40 pmDSM - MYR
2 stops14h 00mSouthwest
ke 6/255:00 pmMYR - DSM
2 stops7h 15mSouthwest
Deal found 4/29$355
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 9/38:00 amDSM - MYR
1 stop5h 42mUnited Airlines
la 9/1311:06 amMYR - DSM
2 stops11h 39mUnited Airlines
Deal found 4/28$359

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated huhtikuu 29, 2025.
Use the filters below to find and compare flights from Des Moines to Myrtle Beach that are best for you.

Fly from

Des Moines

Fly to

Myrtle Beach

Route

Depart

Return

Price

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

la 6/7

1:15 pm-6:30 pm

2 stops28h 15m

Myrtle Beach Intl

ke 6/11

6:00 am-1:33 pm

1 stop8h 33m

$275

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

la 5/24

6:30 am-11:52 am

1 stop4h 22m

Myrtle Beach Intl

la 5/31

6:00 am-10:41 am

1 stop5h 41m

$284

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

la 5/24

12:48 pm-10:31 pm

2 stops8h 43m

Myrtle Beach Intl

la 5/31

5:45 pm-9:38 pm

1 stop4h 53m

$289

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

su 6/22

6:40 pm-9:40 am

2 stops14h 00m

Myrtle Beach Intl

ke 6/25

5:00 pm-11:15 pm

2 stops7h 15m

$355

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

la 6/7

8:00 am-2:35 pm

1 stop5h 35m

Myrtle Beach Intl

ke 6/11

4:55 pm-9:22 pm

1 stop5h 27m

$367

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

ti 6/10

6:47 pm-12:07 am

1 stop4h 20m

$136

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

ti 6/10

6:00 am-5:14 pm

2 stops10h 14m

$141

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

ti 6/10

3:01 pm-2:35 pm

3 stops22h 34m

$374

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Compare providers for flights from Des Moines to Myrtle Beach

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Myrtle Beach in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Myrtle Beach flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Myrtle Beach flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Myrtle Beach flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Myrtle Beach flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Myrtle Beach

Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Myrtle Beach

How far ahead should I book a flight from Des Moines to Myrtle Beach?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Myrtle Beach. Price data was last updated on April 25, 2025.

The price you pay for your flight from Des Moines to Myrtle Beach may vary depending on when you book. For the best chance of a lower fare, look to book 64 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Myrtle Beach?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Myrtle Beach (average of $196). Flying from Des Moines to Myrtle Beach in March is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MYR?

Find hourly flight availability from Des Moines to Myrtle Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated huhtikuu 29, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to Myrtle Beach in the afternoon. If you’re flexible enough to do this you can expect to save up to 10% on your trip compared to booking a flight in the morning.

Rainfall in Myrtle Beach by month

Plan your trip to Myrtle Beach by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Myrtle Beach ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit Myrtle Beach when rainfall is around 3.0 in.

Temperature in Myrtle Beach by month

Plan your trip to Myrtle Beach by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Myrtle Beach, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing Myrtle Beach

Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated huhtikuu 29, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from Des Moines to Myrtle Beach. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,295 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,929 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.6

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Myrtle Beach round-trip?

    Our cheapest airline available from Des Moines to Myrtle Beach is Delta. Our recent data shows that you can find tickets from as low as $284 on this airline. Additional options worth looking into are American Airlines and Southwest, starting at $289 and $355 round-trip. Delta is currently priced 25% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Des Moines to Myrtle Beach one-way?

    The cheapest airlines for a one-way flight from Des Moines to Myrtle Beach are Delta ($136), American Airlines ($141), and United Airlines ($374).

  • Can I find deals for flights from Des Moines to Myrtle Beach that include hotel bookings?

    Yes. In addition to deals on Des Moines to Myrtle Beach flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Myrtle Beach?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Myrtle Beach.

  • Can I find deals for business class flights from Des Moines to Myrtle Beach?

    Yes. Cheapflights offers flight deals from Des Moines to Myrtle Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Myrtle Beach?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Myrtle Beach (average of $196). Flying from Des Moines to Myrtle Beach in March is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Surfside Beach
Little River
Ocean Isle Beach
Conway

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Top 3 airlines flying from Des Moines to Myrtle Beach

Discover the top 3 airlines that operate flights from Des Moines to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated huhtikuu 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$259Average$378FlexibilityNo cancel feeOn-time71%
DeltaCheapest$283Average$376FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$376Average$447FlexibilityNo cancel feeOn-time63%

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