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Myrtle Beach

$249+ Cheap flights from Des Moines to Myrtle Beach (DSM - MYR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/20. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MYR
Jun 19 — Jun 261
Thu 6/19
Thu 6/26
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Myrtle Beach Intl are usually found in September or April, booked 66 days in advance, depart on a Tuesday or Wednesday and return on a Monday

Cheap flight deals from Des Moines to Myrtle Beach

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 14, 2025.

Round-trip from

$249
(American Airlines)

Popular in

June

Cheapest in

September

Average price

$481
From Des Moines to Myrtle Beach Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
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Find flight deals from Des Moines to Myrtle Beach

Cheapest flights from Des Moines to Myrtle Beach
Explore the most affordable flight options available from Des Moines to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 14, 2025.

This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/206:00 amDSM - MYR
1 stop7h 14mAmerican Airlines
Sat 9/275:52 pmMYR - DSM
1 stop6h 21mAmerican Airlines
Deal found 6/13$249
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/85:30 amDSM - MYR
1 stop6h 13mDelta
Tue 7/156:00 amMYR - DSM
1 stop5h 39mDelta
Deal found 6/11$297
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/156:25 amDSM - MYR
2 stops10h 25mSouthwest
Sat 7/192:55 pmMYR - DSM
1 stop8h 40mSouthwest
Deal found 6/13$302
This Mytrip deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/281:13 pmDSM - MYR
2 stops31h 48mMultiple Airlines
Wed 7/25:15 amMYR - DSM
1 stop9h 30mMultiple Airlines
Deal found 6/12$303
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/86:24 amDSM - MYR
1 stop7h 11mUnited Airlines
Fri 7/114:50 pmMYR - DSM
1 stop5h 57mUnited Airlines
Deal found 6/13$342

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2025.
Use the filters below to find and compare flights from Des Moines to Myrtle Beach that are best for you.

Fly from

Des Moines

Fly to

Myrtle Beach

Route

Depart

Return

Price

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 9/20

6:00 am-2:14 pm

1 stop7h 14m

Myrtle Beach Intl

Sat 9/27

5:52 pm-11:13 pm

1 stop6h 21m

$249

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Tue 7/8

5:30 am-12:43 pm

1 stop6h 13m

Myrtle Beach Intl

Tue 7/15

6:00 am-10:39 am

1 stop5h 39m

$297

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Tue 7/15

6:25 am-5:50 pm

2 stops10h 25m

Myrtle Beach Intl

Sat 7/19

2:55 pm-10:35 pm

1 stop8h 40m

$302

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 6/28

1:13 pm-10:01 pm

2 stops31h 48m

Myrtle Beach Intl

Wed 7/2

5:15 am-1:45 pm

1 stop9h 30m

$303

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Tue 7/8

6:24 am-2:35 pm

1 stop7h 11m

Myrtle Beach Intl

Fri 7/11

4:50 pm-9:47 pm

1 stop5h 57m

$342

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/13

Best time to book a flight from Des Moines to Myrtle Beach

Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Myrtle Beach

How far ahead should I book a flight from Des Moines to Myrtle Beach?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Myrtle Beach. Price data was last updated on June 9, 2025.

The price you pay for your flight from Des Moines to Myrtle Beach may vary depending on when you book. For the best chance of a lower fare, look to book 64 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Myrtle Beach?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Myrtle Beach (average of $196). Flying from Des Moines to Myrtle Beach in March is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MYR?

Find hourly flight availability from Des Moines to Myrtle Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 14, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to Myrtle Beach in the afternoon. If you’re flexible enough to do this you can expect to save up to 10% on your trip compared to booking a flight in the morning.

Rainfall in Myrtle Beach by month

Plan your trip to Myrtle Beach by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Myrtle Beach ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit Myrtle Beach when rainfall is around 3.0 in.

Temperature in Myrtle Beach by month

Plan your trip to Myrtle Beach by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Myrtle Beach, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing Myrtle Beach

Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated June 14, 2025.
Southwest
8.0
Very good
4,283 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.6

Crew

8.6

Comfort

8.0

Food

7.1

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,283 reviews
Southwest
8.0
Very good
4,283 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.6

Crew

8.6

Comfort

8.0

Food

7.1

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,958 reviews
Southwest
8.0
Very good
4,283 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.6

Crew

8.6

Comfort

8.0

Food

7.1

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,793 reviews
Southwest
8.0
Very good
4,283 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.6

Crew

8.6

Comfort

8.0

Food

7.1

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,283 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.6

Crew

8.6

Comfort

8.0

Food

7.1

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Myrtle Beach round-trip?

    Our cheapest airline available from Des Moines to Myrtle Beach is American Airlines. Our recent data shows that you can find tickets from as low as $249 on this airline. Additional options worth looking into are Delta and Southwest, starting at $297 and $302 round-trip. American Airlines is currently priced 34% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Myrtle Beach that include hotel bookings?

    Yes. In addition to deals on Des Moines to Myrtle Beach flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Myrtle Beach?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Myrtle Beach.

  • Can I find deals for business class flights from Des Moines to Myrtle Beach?

    Yes. Cheapflights offers flight deals from Des Moines to Myrtle Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Myrtle Beach?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Myrtle Beach (average of $196). Flying from Des Moines to Myrtle Beach in March is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Surfside Beach
Little River
Ocean Isle Beach
Conway

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Top 3 airlines flying from Des Moines to Myrtle Beach

Discover the top 3 airlines that operate flights from Des Moines to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$268Average$384FlexibilityNo cancel feeOn-time71%
DeltaCheapest$291Average$376FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$376Average$447FlexibilityNo cancel feeOn-time63%

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