HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mexico

$533+ Cheap flights from Florence, SC (FLO) to Mexico

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — MEX
May 30 — Jun 61
Sat 5/30
Sat 6/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Florence to Mexico with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Florence to Mexico

Cheapest flights from Florence to Mexico
Explore the most affordable flight options available from Florence to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:05 am
FLO
-
CUN
1 stop5h 25m
American Airlines
Wed 6/172:36 pm
CUN
-
FLO
1 stop6h 24m
American Airlines
Deal found 4/26$533
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:05 am
FLO
-
CUN
1 stop10h 28m
American Airlines
Sat 6/2710:31 am
CUN
-
FLO
1 stop10h 29m
American Airlines
Deal found 4/28$578
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:22 am
FLO
-
CUN
1 stop8h 48m
American Airlines
Mon 10/1212:50 pm
CUN
-
FLO
1 stop10h 13m
American Airlines
Deal found 4/29$629
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/142:35 pm
FLO
-
CUN
2 stops19h 55m
American Airlines
Sun 6/2110:31 am
CUN
-
FLO
1 stop10h 29m
American Airlines
Deal found 4/30$735

Find flight deals from Florence to Mexico

Keep the following information in mind while searching for Florence to Mexico flight deals. Data was last updated April 30, 2026.

Round-trip from

$533
(American Airlines)
From Florence to Mexico
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Florence to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

FlorenceCancún

FLO - CUN

FLOCUN

Florence

Wed 6/10

5:05 am-3:25 pm

2 stops11h 20m

Cancun

Wed 6/17

12:30 pm-10:00 pm

2 stops8h 30m

$537

FlorenceCancún

FLO - CUN

FLOCUN

Florence

Wed 6/24

5:05 am-8:00 pm

2 stops15h 55m

Cancun

Sat 6/27

10:31 am-10:00 pm

1 stop10h 29m

$582
Quickest round-trip

FlorenceCancún

FLO - CUN

FLOCUN

Florence

Wed 10/7

5:22 am-1:10 pm

1 stop8h 48m

Cancun

Mon 10/12

12:50 pm-12:03 am

1 stop10h 13m

$629

FlorenceCancún

FLO - CUN

FLOCUN

Florence

Sun 6/14

2:35 pm-9:30 am

2 stops19h 55m

Cancun

Sun 6/21

2:03 pm-2:10 pm

2 stops23h 07m

$758

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/26

Sorted by cheapest first

Best time to book a flight from Florence to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Mexico
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Florence to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Mexico?

    Florence (FLO), located 2.3 mi from the city center, is the airport you fly out of when you book flights from Florence to Mexico.

  • How long is the flight from Florence, South Carolina to Mexico?

    For as low as $537, American Airlines can have you in Mexico from Florence, South Carolina in 11h 20m. Airlines will cover a distance of 1007 mi.

  • What are the most popular routes from Florence, South Carolina to Mexico?

    The most popular route from Florence, South Carolina to Mexico is Florence - Cancun. You may also consider Florence - Puerto Vallarta Ordaz or Florence - San José del Cabo Los Cabos.

  • Can I find deals for flights from Florence to Mexico that include hotel bookings?

    Yes. In addition to deals on Florence to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Mexico.

  • Can I find deals for business class flights from Florence to Mexico?

    Yes. Cheapflights offers flight deals from Florence to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Florence to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to LaGuardia flights
Charlotte to John F Kennedy Intl flights
Charlotte to Las Vegas flights
Charlotte to Newark flights
Charlotte to O'Hare Intl flights
Charlotte to Denver flights
Charlotte to Dallas/Fort Worth flights
Charlotte to Boston flights
Charlotte to Seattle flights
Charlotte to Hobby flights
Charlotte to Fort Lauderdale flights
Charlotte to George Bush Intcntl flights
Charlotte to Cancún flights
Charlotte to Orlando flights
Charlotte to Miami flights
Charlotte to Los Angeles flights
Charlotte to Baltimore flights
Charlotte to Dulles Intl flights
Charlotte to Salt Lake City flights
Charlotte to Love Field flights
Charleston to John F Kennedy Intl flights
Charlotte to Philadelphia flights
Greenville to LaGuardia flights
Charlotte to Detroit flights
Charleston to Newark flights
Charlotte to Sky Harbor Intl flights
Charleston to LaGuardia flights
Greenville to Newark flights
Charlotte to New Orleans flights
Charlotte to San Francisco flights
Charlotte to Minneapolis flights
Charlotte to San Diego flights
Charlotte to Ontario flights
Charlotte to Nashville flights
Charlotte to Tampa flights
Charleston to Seattle flights
Greenville to John F Kennedy Intl flights
Charlotte to Cozumel flights
Charleston to Boston flights
Savannah to LaGuardia flights
Savannah to Newark flights
Savannah to John F Kennedy Intl flights
Greenville to Denver flights
Charleston to Denver flights
Greenville to Dulles Intl flights
Myrtle Beach to Newark flights
Charlotte to Honolulu flights
Greenville to O'Hare Intl flights
Savannah to Boston flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.