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$578+ Cheap flights from Florence, SC (FLO) to Mexico

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — MEX
Aug 15 — Aug 221
Sat 8/15
Sat 8/22
1 adult, Economy
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Cheap flight deals from Florence to Mexico

Cheapest flights from Florence to Mexico
Explore the most affordable flight options available from Florence to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 16, 2026.

This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:22 am
FLO
-
CUN
2 stops14h 41m
American Airlines
Tue 8/184:30 pm
CUN
-
FLO
2 stops21h 26m
American Airlines
Deal found 7/15$578
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/83:22 pm
FLO
-
CUN
2 stops20h 45m
American Airlines
Fri 8/1410:50 am
CUN
-
FLO
2 stops11h 09m
American Airlines
Deal found 7/12$589
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:22 pm
FLO
-
CUN
2 stops19h 38m
American Airlines
Thu 9/311:31 am
CUN
-
FLO
2 stops10h 28m
American Airlines
Deal found 7/13$593
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:22 pm
FLO
-
CUN
1 stop23h 08m
American Airlines
Mon 8/172:30 pm
CUN
-
FLO
1 stop7h 29m
American Airlines
Deal found 7/12$700
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:22 am
FLO
-
PVR
2 stops9h 41m
American Airlines
Thu 9/311:40 am
PVR
-
FLO
2 stops25h 16m
American Airlines
Deal found 7/13$776
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/242:35 pm
FLO
-
CUN
1 stop19h 59m
American Airlines
Mon 7/2710:34 am
CUN
-
FLO
1 stop26h 36m
American Airlines
Deal found 7/15$850

Find flight deals from Florence to Mexico

Keep the following information in mind while searching for Florence to Mexico flight deals. Data was last updated July 16, 2026.

Round-trip from

$578
(American Airlines)
From Florence to Mexico
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 16, 2026.
Use the filters below to find and compare flights from Florence to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

FlorenceCancún

FLO - CUN

FLOCUN

Florence

Wed 8/12

6:22 am-8:03 pm

2 stops14h 41m

Cancun

Tue 8/18

4:30 pm-2:56 pm

2 stops21h 26m

$578
Quickest round-trip

FlorenceCancún

FLO - CUN

FLOCUN

Florence

Thu 8/27

6:22 am-2:33 pm

1 stop9h 11m

Cancun

Thu 9/3

2:30 pm-10:59 pm

1 stop7h 29m

$589

FlorenceCancún

FLO - CUN

FLOCUN

Florence

Thu 8/13

3:22 pm-2:33 pm

1 stop24h 11m

Cancun

Mon 8/17

2:07 pm-10:59 pm

2 stops7h 52m

$751

FlorencePuerto Vallarta

FLO - PVR

FLOPVR

Florence

Thu 8/27

6:22 am-2:03 pm

2 stops9h 41m

Puerto Vallarta Ordaz

Thu 9/3

11:40 am-2:56 pm

2 stops25h 16m

$776

FlorenceCancún

FLO - CUN

FLOCUN

Florence

Thu 8/13

3:22 pm-9:47 am

2 stops19h 25m

Cancun

Mon 8/17

3:56 pm-2:56 pm

2 stops22h 00m

$1,054

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/15

Sorted by cheapest first

Best time to book a flight from Florence to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Mexico

No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Florence to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Mexico?

    Florence (FLO), located 2.3 mi from the city center, is the airport you fly out of when you book flights from Florence to Mexico.

  • How long is the flight from Florence, South Carolina to Mexico?

    For as low as $578, American Airlines can have you in Mexico from Florence, South Carolina in 14h 41m. Airlines will cover a distance of 1007 mi.

  • What are the most popular routes from Florence, South Carolina to Mexico?

    The most popular route from Florence, South Carolina to Mexico is Florence - Cancun. You may also consider Florence - Puerto Vallarta Ordaz or Florence - San José del Cabo Los Cabos.

  • Can I find deals for flights from Florence to Mexico that include hotel bookings?

    Yes. In addition to deals on Florence to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Mexico.

  • Can I find deals for business class flights from Florence to Mexico?

    Yes. Cheapflights offers flight deals from Florence to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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