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$584+ Cheap flights from Florence, SC (FLO) to Mexico

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/23. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — MEX
Jul 12 — Jul 191
Sun 7/12
Sun 7/19
1 adult, Economy
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Cheap flight deals from Florence to Mexico

Cheapest flights from Florence to Mexico
Explore the most affordable flight options available from Florence to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:17 am
FLO
-
CUN
1 stop10h 18m
American Airlines
Thu 7/3010:34 am
CUN
-
FLO
1 stop12h 03m
American Airlines
Deal found 6/11$584
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/112:35 pm
FLO
-
CUN
2 stops21h 53m
American Airlines
Sat 7/1811:33 am
CUN
-
FLO
2 stops11h 04m
American Airlines
Deal found 6/11$589
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:17 am
FLO
-
SJD
1 stop8h 13m
American Airlines
Sun 8/211:30 am
SJD
-
FLO
1 stop9h 07m
American Airlines
Deal found 6/11$692
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:22 am
FLO
-
CUN
1 stop6h 48m
American Airlines
Sat 10/243:00 pm
CUN
-
FLO
1 stop8h 03m
American Airlines
Deal found 6/11$704
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/242:35 pm
FLO
-
PVR
2 stops23h 54m
American Airlines
Fri 7/3111:38 am
PVR
-
FLO
2 stops24h 32m
American Airlines
Deal found 6/9$752
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:24 am
FLO
-
SJD
2 stops10h 01m
American Airlines
Wed 9/92:11 pm
SJD
-
FLO
2 stops20h 59m
American Airlines
Deal found 6/10$766
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:24 am
FLO
-
SJD
2 stops10h 01m
American Airlines
Thu 9/1012:26 pm
SJD
-
FLO
2 stops21h 52m
American Airlines
Deal found 6/10$771
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:24 am
FLO
-
SJD
2 stops10h 01m
American Airlines
Tue 9/812:27 pm
SJD
-
FLO
2 stops21h 51m
American Airlines
Deal found 6/10$791
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:24 am
FLO
-
SJD
2 stops10h 01m
American Airlines
Tue 9/81:13 pm
SJD
-
FLO
2 stops21h 05m
American Airlines
Deal found 6/10$796
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:05 am
FLO
-
CUN
1 stop5h 25m
American Airlines
Fri 6/262:36 pm
CUN
-
FLO
1 stop6h 24m
American Airlines
Deal found 6/9$799
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:24 am
FLO
-
SJD
2 stops10h 01m
American Airlines
Sat 9/1210:51 am
SJD
-
FLO
2 stops24h 19m
American Airlines
Deal found 6/10$833
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:24 am
FLO
-
SJD
2 stops10h 01m
American Airlines
Sat 9/1210:51 am
SJD
-
FLO
2 stops24h 19m
American Airlines
Deal found 6/10$838

Find flight deals from Florence to Mexico

Keep the following information in mind while searching for Florence to Mexico flight deals. Data was last updated June 12, 2026.

Round-trip from

$584
(American Airlines)
From Florence to Mexico
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Florence to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

FlorenceCancún

FLO - CUN

FLOCUN

Florence

Thu 7/23

5:17 am-2:35 pm

1 stop10h 18m

Cancun

Thu 7/30

10:34 am-11:37 pm

1 stop12h 03m

$584

FlorenceCancún

FLO - CUN

FLOCUN

Florence

Sun 7/12

5:17 am-8:10 pm

2 stops15h 53m

Cancun

Sat 7/18

2:32 pm-11:37 pm

1 stop8h 05m

$589

FlorenceCancún

FLO - CUN

FLOCUN

Florence

Sat 7/11

2:35 pm-11:28 am

2 stops21h 53m

Cancun

Sat 7/18

11:33 am-11:37 pm

2 stops11h 04m

$589
Quickest round-trip

FlorenceSan José del Cabo

FLO - SJD

FLOSJD

Florence

Sun 7/26

5:17 am-10:30 am

1 stop8h 13m

San José del Cabo Los Cabos

Sun 8/2

11:30 am-11:37 pm

1 stop9h 07m

$692

FlorencePuerto Vallarta

FLO - PVR

FLOPVR

Florence

Fri 7/24

2:35 pm-12:29 pm

2 stops23h 54m

Puerto Vallarta Ordaz

Fri 7/31

11:38 am-2:10 pm

2 stops24h 32m

$752

FlorenceSan José del Cabo

FLO - SJD

FLOSJD

Florence

Fri 9/4

3:22 pm-9:47 am

2 stops21h 25m

San José del Cabo Los Cabos

Tue 9/8

2:25 pm-1:18 pm

2 stops19h 53m

$886

FlorenceSan José del Cabo

FLO - SJD

FLOSJD

Florence

Sat 9/5

2:37 pm-9:47 am

2 stops22h 10m

San José del Cabo Los Cabos

Sat 9/12

10:51 am-2:10 pm

2 stops24h 19m

$890

FlorenceSan José del Cabo

FLO - SJD

FLOSJD

Florence

Sun 9/6

9:00 am-9:47 am

2 stops27h 47m

San José del Cabo Los Cabos

Tue 9/8

2:25 pm-1:18 pm

2 stops19h 53m

$895

FlorenceSan José del Cabo

FLO - SJD

FLOSJD

Florence

Wed 9/2

6:24 am-1:25 pm

2 stops10h 01m

San José del Cabo Los Cabos

Mon 9/7

10:47 am-10:59 pm

2 stops9h 12m

$920

FlorenceSan José del Cabo

FLO - SJD

FLOSJD

Florence

Mon 9/7

3:22 pm-11:27 am

2 stops23h 05m

San José del Cabo Los Cabos

Fri 9/11

2:11 pm-1:18 pm

2 stops20h 07m

$925

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 11 resultsSorted by cheapest first
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Best time to book a flight from Florence to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Mexico
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Florence to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Mexico?

    Florence (FLO), located 2.3 mi from the city center, is the airport you fly out of when you book flights from Florence to Mexico.

  • How long is the flight from Florence, South Carolina to Mexico?

    For as low as $589, American Airlines can have you in Mexico from Florence, South Carolina in 15h 53m. Airlines will cover a distance of 1007 mi.

  • What are the most popular routes from Florence, South Carolina to Mexico?

    The most popular route from Florence, South Carolina to Mexico is Florence - Cancun. You may also consider Florence - Puerto Vallarta Ordaz or Florence - San José del Cabo Los Cabos.

  • Can I find deals for flights from Florence to Mexico that include hotel bookings?

    Yes. In addition to deals on Florence to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Mexico.

  • Can I find deals for business class flights from Florence to Mexico?

    Yes. Cheapflights offers flight deals from Florence to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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