$170+ Cheap flights from Des Moines to Jacksonville (DSM - JAX)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JAX
Nov 13 — Nov 201
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Jacksonville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Jacksonville
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Cheapest flights from Des Moines to JacksonvilleExplore the most affordable flight options available from Des Moines to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2026.
Explore the most affordable flight options available from Des Moines to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2026.
This Delta deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:58 pm -
1 stop6h 57m
Thu 12/176:00 am -
1 stop5h 49m
Deal found 10/9![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/168:00 am -
1 stop5h 25m
Thu 1/77:30 am -
2 stops9h 41m
Deal found 10/13![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/167:00 am -
2 stops9h 00m
Thu 1/72:00 pm -
2 stops8h 35m
Deal found 10/13![Southwest logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:43 am -
1 stop24h 54m
Wed 11/47:03 pm -
2 stops21h 22m
Deal found 10/12![Multiple Airlines logo]()
$352
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:30 am -
1 stop5h 24m
Sun 11/225:05 am -
1 stop6h 39m
Deal found 10/13![Delta logo]()
$364
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:00 am -
2 stops9h 00m
Sun 11/227:05 pm -
1 stop5h 00m
Deal found 10/13![Southwest logo]()
$369
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/167:00 am -
2 stops9h 00m
Tue 1/56:05 am -
2 stops9h 10m
Deal found 10/9![Southwest logo]()
$374
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
2 stops11h 20m
Mon 11/237:05 pm -
1 stop5h 00m
Deal found 10/12![Southwest logo]()
$375
This Delta deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:54 pm -
1 stop4h 02m
Tue 11/105:05 am -
1 stop6h 39m
Deal found 10/10![Delta logo]()
$376
This Southwest deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:25 am -
2 stops12h 00m
Thu 1/72:00 pm -
2 stops8h 35m
Deal found 10/10![Southwest logo]()
$380
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:25 pm -
1 stop4h 50m
Sun 12/132:10 pm -
2 stops9h 50m
Deal found 10/14![Southwest logo]()
$381
Best flights from Des Moines to JacksonvilleDiscover carefully curated flight deals from Des Moines to Jacksonville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 14, 2026.
Discover carefully curated flight deals from Des Moines to Jacksonville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 14, 2026.
This Delta deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:58 pm -
1 stop6h 57m
Thu 12/176:00 am -
1 stop5h 49m
Deal found 10/9![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/168:00 am -
1 stop5h 10m
Thu 1/76:28 pm -
1 stop6h 12m
Deal found 10/13![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:30 am -
2 stops9h 40m
Wed 12/95:25 pm -
1 stop5h 56m
Deal found 10/13![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:20 am -
2 stops9h 15m
Wed 11/186:05 am -
2 stops9h 10m
Deal found 10/13![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:30 am -
1 stop5h 24m
Wed 11/183:07 pm -
1 stop5h 08m
Deal found 10/13![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/168:00 am -
1 stop5h 25m
Wed 1/611:34 am -
2 stops10h 49m
Deal found 10/10![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:53 pm -
1 stop4h 16m
Thu 1/711:29 am -
1 stop5h 58m
Deal found 10/10![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:10 am -
2 stops7h 25m
Thu 1/72:00 pm -
2 stops8h 35m
Deal found 10/10![Southwest logo]()
$374
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/167:00 am -
2 stops9h 00m
Tue 1/56:05 am -
2 stops9h 10m
Deal found 10/9![Southwest logo]()
$374
This Delta deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:54 pm -
1 stop4h 02m
Tue 11/105:05 am -
1 stop6h 39m
Deal found 10/10![Delta logo]()
$376
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/174:25 pm -
1 stop4h 50m
Thu 1/72:00 pm -
2 stops8h 35m
Deal found 10/9![Southwest logo]()
$381
This Delta deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/15:15 pm -
1 stop4h 28m
Fri 3/56:30 am -
1 stop4h 48m
Deal found 10/9![Delta logo]()
$388
Last-minute flights from Des Moines to JacksonvilleDiscover last-minute flight deals from Des Moines to Jacksonville. Data last updated October 14, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Jacksonville. Data last updated October 14, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:43 am -
1 stop24h 54m
Wed 11/47:03 pm -
2 stops21h 22m
Deal found 10/12![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:52 pm -
1 stop13h 53m
Wed 10/287:03 pm -
2 stops20h 39m
Deal found 10/9![Multiple Airlines logo]()
$386
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:16 pm -
1 stop6h 14m
Sat 11/147:00 am -
1 stop8h 39m
Deal found 10/10![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:23 am -
1 stop5h 38m
Sat 11/147:00 am -
2 stops10h 07m
Deal found 10/10![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:20 am -
2 stops9h 15m
Sat 11/1412:35 pm -
2 stops9h 05m
Deal found 10/10![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:54 pm -
1 stop4h 02m
Tue 11/105:05 am -
1 stop6h 39m
Deal found 10/10![Delta logo]()
$376
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:25 pm -
2 stops6h 20m
Mon 11/168:45 am -
1 stop13h 05m
Deal found 10/12![Southwest logo]()
$387
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:58 pm -
2 stops9h 00m
Mon 11/165:08 pm -
1 stop7h 18m
Deal found 10/13![American Airlines logo]()
$383
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:30 am -
1 stop5h 24m
Sun 11/225:05 am -
1 stop6h 39m
Deal found 10/13![Delta logo]()
$364
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:00 am -
2 stops9h 00m
Sun 11/227:05 pm -
1 stop5h 00m
Deal found 10/13![Southwest logo]()
$369
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
2 stops11h 20m
Mon 11/237:05 pm -
1 stop5h 00m
Deal found 10/12![Southwest logo]()
$375
One-way flights from Des Moines to JacksonvilleSearch for one-way flight options from Des Moines to Jacksonville. Find affordable one-way fares based on user searches. Data last updated October 14, 2026.
Search for one-way flight options from Des Moines to Jacksonville. Find affordable one-way fares based on user searches. Data last updated October 14, 2026.
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/162:05 pm -
1 stop7h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![American Airlines logo]()
$170
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/59:25 am -
2 stops11h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![United Airlines logo]()
$175
This KAYAK deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:36 am -
1 stop6h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Delta logo]()
$189
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:50 am -
1 stop7h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![United Airlines logo]()
$225
This deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:55 am -
1 stop7h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![United Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:00 am -
2 stops29h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Allegiant Air logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:00 am -
3 stops46h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Multiple Airlines logo]()
$431
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:12 pm -
1 stop5h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![American Airlines logo]()
$454
Find flight deals from Des Moines to Jacksonville
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Jacksonville (JAX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $339 (Delta) |
One-way from | $170 (American Airlines) |
Popular in | March |
Cheapest in | July |
Average price | $280 |
Good round-trip deal | $120 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 14, 2026.
Use the filters below to find and compare flights from Des Moines to Jacksonville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesJacksonville
DSM Des Moines - JAX Jacksonville
DSMJAX
Des Moines
Wed 12/16
2:05 pm-10:52 pm
1 stop7h 47m
Jacksonville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$170
Quickest round-trip
Des MoinesJacksonville
DSM Des Moines - JAX Jacksonville
DSMJAX
Des Moines
Wed 1/13
10:57 am-4:22 pm
1 stop4h 25m
Jacksonville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$170
Des MoinesJacksonville
DSM Des Moines - JAX Jacksonville
DSMJAX
Des Moines
Tue 1/5
3:26 pm-10:33 pm
1 stop6h 07m
Jacksonville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$170
Des MoinesJacksonville
DSM Des Moines - JAX Jacksonville
DSMJAX
Des Moines
Tue 1/5
9:25 am-10:12 pm
2 stops11h 47m
Jacksonville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$175
Des MoinesJacksonville
DSM Des Moines - JAX Jacksonville
DSMJAX
Des Moines
Wed 12/16
7:00 am-5:00 pm
2 stops9h 00m
Jacksonville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$175
Des MoinesJacksonville
DSM Des Moines - JAX Jacksonville
DSMJAX
Des Moines
Wed 1/13
6:55 am-6:00 pm
2 stops10h 05m
Jacksonville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$175
Des MoinesJacksonville
DSM Des Moines - JAX Jacksonville
DSMJAX
Des Moines
Tue 1/5
7:00 am-5:00 pm
2 stops9h 00m
Jacksonville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$175
Des MoinesJacksonville
DSM Des Moines - JAX Jacksonville
DSMJAX
Des Moines
Thu 11/19
11:36 am-6:54 pm
1 stop6h 18m
Jacksonville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$189
Des MoinesJacksonville
DSM Des Moines - JAX Jacksonville
DSMJAX
Des Moines
Thu 11/26
9:50 am-6:01 pm
1 stop7h 11m
Jacksonville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$225
Des MoinesJacksonville
DSM Des Moines - JAX Jacksonville
DSMJAX
Des Moines
Sun 11/1
9:55 am-6:01 pm
1 stop7h 06m
Jacksonville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$262
Showing 1-10 of 23 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Jacksonville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Jacksonville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Jacksonville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Jacksonville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Jacksonville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Jacksonville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Jacksonville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Jacksonville
Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Des Moines with our price prediction graph.
DSM-JAX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Jacksonville
What is the cheapest month to book a flight from Des Moines to Jacksonville?
Currently, July is the cheapest month in which you can book a flight from Des Moines to Jacksonville (average of $115). Flying from Des Moines to Jacksonville in March is currently the most expensive (average of $455). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Jacksonville?
Airfare is typical for this route at the moment.
Des Moines to Jacksonville flights typically cost between $108 and $374 in December.The cheapest round-trip price found within the last 5 days was $339 on Delta (Dec 10-Dec 17).
Reviews of airlines servicing Jacksonville
Get insights into the airlines that provide service to Jacksonville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Jacksonville. Reviews last updated October 14, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAllegiant Air from Des Moines to Jacksonville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top 4 airlines flying from Des Moines to Jacksonville
Discover the top 4 airlines that operate flights from Des Moines to Jacksonville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$64 | Average$118 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$180 | Average$396 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$203 | Average$427 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$222 | Average$407 | FlexibilityNo cancel fee | On-timeN/A |