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$50+ Cheap flights from Des Moines to Jacksonville (DSM - JAX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JAX
oct.. 19 — oct.. 261
dg. 10/19
dg. 10/26
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Jacksonville are usually found in August or July, booked 50 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Des Moines to Jacksonville

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Jacksonville (JAX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated setembre 19, 2025.

Round-trip from

$86
(Mytrip)

One-way from

$50
(FlightHub)

Popular in

March

Cheapest in

August

Average price

$150

Good round-trip deal

$93 or less

Good one-way deal

$96 or less
From Des Moines to Jacksonville
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One-way flight from Des Moines to Jacksonville
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Highest demand for flights based on searches. 27% potential increase in price ($111 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Des Moines to Jacksonville.
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Price to beat on a one-way flight from Des Moines to Jacksonville.
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Find flight deals from Des Moines to Jacksonville

Cheapest flights from Des Moines to Jacksonville
Explore the most affordable flight options available from Des Moines to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on setembre 19, 2025.

This Mytrip deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dg. 10/266:30 amDSM - JAX
Nonstop2h 43mAllegiant Air
dg. 11/212:03 pmJAX - DSM
Nonstop2h 58mAllegiant Air
Deal found 9/18$86
This Trip.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dg. 11/27:30 amDSM - JAX
Nonstop2h 43mAllegiant Air
dg. 11/912:03 pmJAX - DSM
Nonstop2h 58mAllegiant Air
Deal found 9/18$94
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dg. 11/97:30 amDSM - JAX
Nonstop2h 43mMultiple Airlines
dv. 11/143:20 pmJAX - DSM
2 stops43h 40mMultiple Airlines
Deal found 9/17$241
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dg. 11/97:30 amDSM - JAX
Nonstop2h 43mAllegiant Air
dv. 11/149:21 pmJAX - DSM
2 stops20h 17mAllegiant Air
Deal found 9/17$242
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 10/3110:54 amDSM - JAX
2 stops21h 04mMultiple Airlines
dg. 11/212:03 pmJAX - DSM
Nonstop2h 58mMultiple Airlines
Deal found 9/19$245
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 10/26:30 amDSM - JAX
Nonstop2h 43mMultiple Airlines
dl. 10/69:43 amJAX - DSM
2 stops53h 09mMultiple Airlines
Deal found 9/16$259
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dg. 11/27:30 amDSM - JAX
Nonstop2h 43mMultiple Airlines
dg. 11/911:18 amJAX - DSM
3 stops26h 29mMultiple Airlines
Deal found 9/18$310
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dc. 12/103:15 pmDSM - JAX
1 stop7h 05mDelta
dl. 12/151:59 pmJAX - DSM
1 stop8h 16mDelta
Deal found 9/18$312

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated setembre 19, 2025.
Use the filters below to find and compare flights from Des Moines to Jacksonville that are best for you.

Fly from

Des Moines

Fly to

Jacksonville

Route

Depart

Return

Price

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

dg. 11/9

7:30 am-11:13 am

Nonstop2h 43m

Jacksonville

dv. 11/14

3:20 pm-10:00 am

2 stops43h 40m

$241

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

dv. 10/31

10:54 am-8:58 am

2 stops21h 04m

Jacksonville

dg. 11/2

12:03 pm-2:01 pm

Nonstop2h 58m

$245

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

dg. 11/2

7:30 am-11:13 am

Nonstop2h 43m

Jacksonville

dg. 11/9

9:51 am-9:33 pm

2 stops12h 42m

$269

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

dj. 10/2

6:30 am-10:13 am

Nonstop2h 43m

Jacksonville

dl. 10/6

4:16 pm-1:52 pm

3 stops46h 36m

$269

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

dc. 12/10

3:15 pm-11:20 pm

1 stop7h 05m

Jacksonville

dl. 12/15

1:59 pm-9:15 pm

1 stop8h 16m

$312

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

dt. 10/21

4:45 pm-10:05 pm

1 stop4h 20m

Jacksonville

dl. 10/27

8:15 pm-11:30 pm

1 stop4h 15m

$312

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

dv. 10/24

3:53 pm-9:59 pm

1 stop5h 06m

Jacksonville

dc. 10/29

12:44 pm-5:42 pm

1 stop5h 58m

$322

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

dl. 12/1

6:50 pm-11:55 pm

1 stop4h 05m

Jacksonville

ds. 12/13

11:25 am-2:55 pm

1 stop4h 30m

$329

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

dt. 12/23

1:18 pm-11:21 pm

2 stops9h 03m

Jacksonville

dc. 12/31

6:00 am-12:54 pm

2 stops7h 54m

$332

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

dl. 11/3

12:54 pm-10:59 pm

2 stops9h 05m

Jacksonville

dl. 11/10

4:21 pm-11:30 pm

1 stop8h 09m

$333

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 22 results
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Best time to book a flight from Des Moines to Jacksonville

Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Jacksonville

How far ahead should I book a flight from Des Moines to Jacksonville?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Jacksonville. Price data was last updated on September 12, 2025.

The price you pay for your flight from Des Moines to Jacksonville may vary depending on when you book. For the best chance of a lower fare, look to book 49 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Jacksonville?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Jacksonville (average of $278). Flying from Des Moines to Jacksonville in March is currently the most expensive (average of $365). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to JAX?

Find hourly flight availability from Des Moines to Jacksonville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated setembre 19, 2025.

When flying from Des Moines to Jacksonville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 77% versus a flight at noon.

Reviews of airlines servicing Jacksonville

Get insights into the airlines that provide service to Jacksonville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Jacksonville. Reviews last updated setembre 19, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Des Moines to Jacksonville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,964 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Allegiant Air
7.2
Good
699 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Des Moines to Jacksonville flight route?

    This flight path from Des Moines to Jacksonville was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Des Moines to Jacksonville?

    For as low as $269, Allegiant Air can have you in Jacksonville from Des Moines in 2h 43m. The distance between Des Moines and Jacksonville is about 1012 mi. Generally, flights for this route are nonstop.

  • What are the cheapest airlines flying from Des Moines to Jacksonville round-trip?

    Cheapflights users have booked flights from Des Moines to Jacksonville round-trip from $82. Other airlines that can offer you cheap pricing are Delta, from $231, and American Airlines, from $301. These flights start at 72% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to Jacksonville one-way?

    $50 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $149 and $154, respectively.

  • What are the cheapest flights from Des Moines to Jacksonville?

    The cheapest flight price from Des Moines to Jacksonville is $90. On average you can expect to pay $104. The most popular route, (Des Moines - Jacksonville), can usually be booked for $130.

  • Can I find deals for flights from Des Moines to Jacksonville that include hotel bookings?

    Yes. In addition to deals on Des Moines to Jacksonville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Jacksonville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Jacksonville.

  • Can I find deals for business class flights from Des Moines to Jacksonville?

    Yes. Cheapflights offers flight deals from Des Moines to Jacksonville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Jacksonville?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Jacksonville (average of $278). Flying from Des Moines to Jacksonville in March is currently the most expensive (average of $365). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Jacksonville?

Book flights to Jacksonville if you plan to visit one of these locations
Jacksonville Beach
Orange Park
Kingsland
Fernandina Beach
Waycross

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Alternative routes for Des Moines to Jacksonville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to Jacksonville

Discover the top 4 airlines that operate flights from Des Moines to Jacksonville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated setembre 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$82Average$92FlexibilityNo cancel feeOn-time88%
DeltaCheapest$231Average$382FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$301Average$385FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$308Average$386FlexibilityNo cancel feeOn-time63%

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