$77+ Cheap flights from Des Moines to Jacksonville (DSM - JAX)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/18. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JAX
Apr 15 — Apr 221
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Jacksonville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Jacksonville are usually found in October or August, booked 49 days in advance, depart on a Monday or Tuesday and return on a Monday
Cheap flight deals from Des Moines to Jacksonville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to JacksonvilleExplore the most affordable flight options available from Des Moines to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.
Explore the most affordable flight options available from Des Moines to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/193:59 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Sun 7/268:23 pm
JAX
- DSM
Nonstop2h 35m
Allegiant Air
Deal found 3/14![Allegiant Air logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/53:59 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Thu 7/99:32 pm
JAX
- DSM
Nonstop2h 35m
Allegiant Air
Deal found 3/12![Allegiant Air logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/214:01 pm
DSM
- JAX
Nonstop2h 29m
Allegiant Air
Sun 6/288:20 pm
JAX
- DSM
Nonstop2h 37m
Allegiant Air
Deal found 3/12![Allegiant Air logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/193:59 pm
DSM
- JAX
Nonstop2h 34m
Multiple Airlines
Sun 7/2610:33 pm
JAX
- DSM
1 stop18h 17m
Multiple Airlines
Deal found 3/14![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:00 am
DSM
- JAX
2 stops33h 14m
Multiple Airlines
Thu 7/99:32 pm
JAX
- DSM
Nonstop2h 35m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:00 am
DSM
- JAX
2 stops31h 51m
Allegiant Air
Thu 6/49:21 pm
JAX
- DSM
Nonstop2h 37m
Allegiant Air
Deal found 3/15![Allegiant Air logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/214:01 pm
DSM
- JAX
Nonstop2h 29m
Multiple Airlines
Sun 6/285:12 pm
JAX
- DSM
1 stop6h 40m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/83:15 pm
DSM
- JAX
1 stop5h 00m
Southwest
Wed 4/157:20 am
JAX
- DSM
1 stop5h 05m
Southwest
Deal found 3/12![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:20 am
DSM
- JAX
1 stop7h 00m
United Airlines
Wed 4/1511:32 am
JAX
- DSM
2 stops10h 02m
United Airlines
Deal found 3/11![United Airlines logo]()
$340
Best flights from Des Moines to JacksonvilleDiscover carefully curated flight deals from Des Moines to Jacksonville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 16, 2026.
Discover carefully curated flight deals from Des Moines to Jacksonville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 16, 2026.
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:40 am
DSM
- JAX
2 stops10h 05m
Southwest
Sat 5/25:10 am
JAX
- DSM
1 stop9h 20m
Southwest
Deal found 3/11![Southwest logo]()
$382
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:02 am
DSM
- JAX
1 stop6h 05m
American Airlines
Wed 6/36:05 pm
JAX
- DSM
1 stop7h 05m
American Airlines
Deal found 3/15![American Airlines logo]()
$405
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:30 am
DSM
- JAX
2 stops9h 50m
United Airlines
Sat 4/2511:25 am
JAX
- DSM
2 stops10h 09m
United Airlines
Deal found 3/11![United Airlines logo]()
$412
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:02 am
DSM
- JAX
1 stop6h 05m
American Airlines
Thu 6/47:59 pm
JAX
- DSM
1 stop5h 11m
American Airlines
Deal found 3/15![American Airlines logo]()
$417
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:20 pm
DSM
- JAX
1 stop4h 45m
Southwest
Mon 4/205:10 am
JAX
- DSM
1 stop9h 00m
Southwest
Deal found 3/15![Southwest logo]()
$426
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:04 am
DSM
- JAX
2 stops9h 32m
United Airlines
Wed 4/158:00 am
JAX
- DSM
1 stop5h 29m
United Airlines
Deal found 3/11![United Airlines logo]()
$445
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:25 am
DSM
- JAX
2 stops10h 30m
Southwest
Mon 5/46:05 am
JAX
- DSM
2 stops8h 05m
Southwest
Deal found 3/12![Southwest logo]()
$451
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:20 am
DSM
- JAX
2 stops6h 15m
Southwest
Fri 7/317:45 am
JAX
- DSM
1 stop4h 45m
Southwest
Deal found 3/14![Southwest logo]()
$472
Last-minute flights from Des Moines to JacksonvilleDiscover last-minute flight deals from Des Moines to Jacksonville. Data last updated March 16, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Jacksonville. Data last updated March 16, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:00 am
DSM
- JAX
2 stops9h 05m
American Airlines
Wed 4/156:00 am
JAX
- DSM
2 stops8h 46m
American Airlines
Deal found 3/11![American Airlines logo]()
$366
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/13:04 pm
DSM
- JAX
1 stop6h 00m
United Airlines
Sat 4/44:19 pm
JAX
- DSM
1 stop8h 23m
United Airlines
Deal found 3/11![United Airlines logo]()
$370
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/73:15 pm
DSM
- JAX
1 stop5h 00m
Southwest
Sat 4/115:10 am
JAX
- DSM
1 stop9h 20m
Southwest
Deal found 3/11![Southwest logo]()
$360
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/83:15 pm
DSM
- JAX
1 stop5h 00m
Southwest
Wed 4/157:20 am
JAX
- DSM
1 stop5h 05m
Southwest
Deal found 3/12![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:20 am
DSM
- JAX
1 stop7h 00m
United Airlines
Wed 4/1511:32 am
JAX
- DSM
2 stops10h 02m
United Airlines
Deal found 3/11![United Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:01 pm
DSM
- JAX
1 stop5h 30m
American Airlines
Sun 4/125:45 am
JAX
- DSM
1 stop5h 41m
American Airlines
Deal found 3/11![American Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:01 pm
DSM
- JAX
1 stop5h 30m
American Airlines
Sat 4/253:52 pm
JAX
- DSM
1 stop6h 35m
American Airlines
Deal found 3/11![American Airlines logo]()
$382
One-way flights from Des Moines to JacksonvilleSearch for one-way flight options from Des Moines to Jacksonville. Find affordable one-way fares based on user searches. Data last updated March 16, 2026.
Search for one-way flight options from Des Moines to Jacksonville. Find affordable one-way fares based on user searches. Data last updated March 16, 2026.
This Booking.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/185:02 pm
DSM
- JAX
Nonstop2h 29m
Allegiant Air
Deal found 3/12![Allegiant Air logo]()
$77
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:20 pm
DSM
- JAX
1 stop5h 26m
United Airlines
Deal found 3/11![United Airlines logo]()
$168
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:55 am
DSM
- JAX
1 stop6h 18m
Delta
Deal found 3/11![Delta logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:00 am
DSM
- JAX
2 stops48h 38m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$190
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:01 pm
DSM
- JAX
1 stop5h 30m
American Airlines
Deal found 3/12![American Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:30 am
DSM
- JAX
2 stops32h 34m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$200
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/144:20 pm
DSM
- JAX
1 stop4h 45m
Southwest
Deal found 3/11![Southwest logo]()
$203
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:02 am
DSM
- JAX
2 stops9h 00m
United Airlines
Deal found 3/11![United Airlines logo]()
$208
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/265:01 pm
DSM
- JAX
1 stop5h 30m
American Airlines
Deal found 3/12![American Airlines logo]()
$213
Find flight deals from Des Moines to Jacksonville
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Jacksonville (JAX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $124 (Kiwi.com) |
One-way from | $77 (Booking.com) |
Popular in | March |
Cheapest in | October |
Average price | $441 |
Good round-trip deal | $150 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Des Moines to Jacksonville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Sat 4/25
6:40 am-5:45 pm
2 stops10h 05m
Jacksonville
Sat 5/2
5:10 am-1:30 pm
1 stop9h 20m
$382
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Wed 5/27
6:02 am-1:07 pm
1 stop6h 05m
Jacksonville
Wed 6/3
6:05 pm-12:10 am
1 stop7h 05m
$405
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Sun 4/19
5:30 am-4:20 pm
2 stops9h 50m
Jacksonville
Sat 4/25
11:25 am-8:34 pm
2 stops10h 09m
$412
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Fri 5/29
6:02 am-1:07 pm
1 stop6h 05m
Jacksonville
Thu 6/4
7:59 pm-12:10 am
1 stop5h 11m
$417
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Fri 4/17
4:20 pm-10:05 pm
1 stop4h 45m
Jacksonville
Mon 4/20
5:10 am-1:10 pm
1 stop9h 00m
$426
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Sat 4/11
8:04 am-6:36 pm
2 stops9h 32m
Jacksonville
Wed 4/15
8:00 am-12:29 pm
1 stop5h 29m
$445
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Mon 4/27
5:25 am-4:55 pm
2 stops10h 30m
Jacksonville
Mon 5/4
6:05 am-1:10 pm
2 stops8h 05m
$451
Quickest round-trip
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Wed 7/22
5:20 am-12:35 pm
2 stops6h 15m
Jacksonville
Fri 7/31
7:45 am-11:30 am
1 stop4h 45m
$472
Cheapest one-way
Quickest one-way
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Thu 6/18
5:02 pm-8:31 pm
Nonstop2h 29m
$84
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Wed 5/13
3:20 pm-9:46 pm
1 stop5h 26m
$168
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Jacksonville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Jacksonville in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Jacksonville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Jacksonville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Jacksonville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Jacksonville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Jacksonville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Jacksonville
Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Des Moines with our price prediction graph.
DSM-JAX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Jacksonville
Prices
More
How far ahead should I book a flight from Des Moines to Jacksonville?
Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Jacksonville. Price data was last updated on March 13, 2026.
The price you pay for your flight from Des Moines to Jacksonville may vary depending on when you book. For the best chance of a lower fare, look to book 49 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to Jacksonville?
Currently, October is the cheapest month in which you can book a flight from Des Moines to Jacksonville (average of $42). Flying from Des Moines to Jacksonville in March is currently the most expensive (average of $349). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What’s the top layover airport for flights from Des Moines to Jacksonville?
Share of 1-stop round-trip flights from Des Moines to Jacksonville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Dallas (DFW) – chosen by Cheapflights users on 50% of 1-stop itineraries from Des Moines to Jacksonville on Cheapflights.
What’s the cheapest layover airport for flights from Des Moines to Jacksonville?
Average round-trip fare for 1-stop flights from Des Moines to Jacksonville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $276.
What’s the fastest layover option from Des Moines to Jacksonville?
Shortest average travel time for 1-stop one-way flights from Des Moines to Jacksonville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via St. Louis (STL) have the shortest average one-way travel time for 1-stop routes: 4h 00m.
Which airport typically offers the quickest layover for flights from Des Moines to Jacksonville?
Average layover duration for 1-stop one-way flights from Des Moines to Jacksonville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via St. Louis (STL) offer the fastest connection on this route, with an average layover time of 1h 15m.
Reviews of airlines servicing Jacksonville
Get insights into the airlines that provide service to Jacksonville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Jacksonville. Reviews last updated March 16, 2026.
Read reviews from past customers who have flown Southwest,Delta, andAllegiant Air from Des Moines to Jacksonville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Overall
8.0
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
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Book flights to Jacksonville if you plan to visit one of these locationsJacksonville Beach
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Top 4 airlines flying from Des Moines to Jacksonville
Discover the top 4 airlines that operate flights from Des Moines to Jacksonville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$76 | Average$94 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$150 | Average$398 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$216 | Average$377 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$396 | FlexibilityNo cancel fee | On-time63% |