$60+ Cheap flights from Des Moines to Jacksonville (DSM - JAX)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JAX
Aug 13 — Aug 201
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Jacksonville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Jacksonville are usually found in October or August, booked 49 days in advance, depart on a Monday or Wednesday and return on a Monday
Cheap flight deals from Des Moines to Jacksonville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to JacksonvilleExplore the most affordable flight options available from Des Moines to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2026.
Explore the most affordable flight options available from Des Moines to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2026.
This Trip.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:12 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Thu 8/139:36 pm
JAX
- DSM
Nonstop2h 43m
Allegiant Air
Deal found 7/9![Allegiant Air logo]()
$83
This Super.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:12 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Sun 8/169:36 pm
JAX
- DSM
Nonstop2h 43m
Allegiant Air
Deal found 7/11![Allegiant Air logo]()
$100
This Super.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/23:59 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Sun 8/99:36 pm
JAX
- DSM
Nonstop2h 43m
Allegiant Air
Deal found 7/9![Allegiant Air logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/24:57 pm
DSM
- JAX
2 stops47h 37m
Multiple Airlines
Sun 8/99:36 pm
JAX
- DSM
Nonstop2h 43m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:08 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Sun 8/28:23 pm
JAX
- DSM
Nonstop2h 35m
Allegiant Air
Deal found 7/9![Allegiant Air logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:08 pm
DSM
- JAX
Nonstop2h 34m
Multiple Airlines
Sun 8/26:29 pm
JAX
- DSM
2 stops25h 35m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:12 pm
DSM
- JAX
Nonstop2h 34m
Multiple Airlines
Thu 8/1310:33 pm
JAX
- DSM
1 stop19h 44m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:12 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Fri 8/1410:12 am
JAX
- DSM
2 stops14h 02m
Allegiant Air
Deal found 7/13![Allegiant Air logo]()
$215
Best flights from Des Moines to JacksonvilleDiscover carefully curated flight deals from Des Moines to Jacksonville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 14, 2026.
Discover carefully curated flight deals from Des Moines to Jacksonville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:12 pm
DSM
- JAX
Nonstop2h 34m
Multiple Airlines
Fri 8/146:29 pm
JAX
- DSM
3 stops40h 40m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$233
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:54 pm
DSM
- JAX
1 stop4h 05m
Delta
Tue 10/65:33 pm
JAX
- DSM
1 stop6h 01m
Delta
Deal found 7/10![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:40 pm
DSM
- JAX
1 stop5h 35m
Southwest
Wed 9/235:25 pm
JAX
- DSM
1 stop5h 30m
Southwest
Deal found 7/10![Southwest logo]()
$275
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/241:35 pm
DSM
- JAX
1 stop7h 11m
United Airlines
Fri 8/285:00 pm
JAX
- DSM
1 stop6h 30m
United Airlines
Deal found 7/11![United Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:54 pm
DSM
- JAX
1 stop4h 05m
Delta
Mon 10/56:59 pm
JAX
- DSM
1 stop4h 30m
Delta
Deal found 7/10![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am
DSM
- JAX
2 stops8h 35m
Southwest
Mon 9/147:00 am
JAX
- DSM
1 stop5h 25m
Southwest
Deal found 7/10![Southwest logo]()
$280
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:40 am
DSM
- JAX
2 stops6h 40m
Southwest
Fri 8/282:00 pm
JAX
- DSM
2 stops9h 10m
Southwest
Deal found 7/9![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:00 am
DSM
- JAX
2 stops11h 54m
United Airlines
Sat 9/199:25 am
JAX
- DSM
2 stops9h 03m
United Airlines
Deal found 7/10![United Airlines logo]()
$407
This Southwest deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:15 am
DSM
- JAX
2 stops8h 30m
Southwest
Sun 8/303:00 pm
JAX
- DSM
2 stops8h 50m
Southwest
Deal found 7/12![Southwest logo]()
$390
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:40 am
DSM
- JAX
2 stops8h 35m
Southwest
Fri 8/142:00 pm
JAX
- DSM
2 stops9h 10m
Southwest
Deal found 7/13![Southwest logo]()
$390
Last-minute flights from Des Moines to JacksonvilleDiscover last-minute flight deals from Des Moines to Jacksonville. Data last updated July 14, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Jacksonville. Data last updated July 14, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:08 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Sun 8/28:23 pm
JAX
- DSM
Nonstop2h 35m
Allegiant Air
Deal found 7/9![Allegiant Air logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:08 pm
DSM
- JAX
Nonstop2h 34m
Multiple Airlines
Sun 8/26:29 pm
JAX
- DSM
2 stops25h 35m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$209
This Super.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/23:59 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Sun 8/99:36 pm
JAX
- DSM
Nonstop2h 43m
Allegiant Air
Deal found 7/9![Allegiant Air logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/24:57 pm
DSM
- JAX
2 stops47h 37m
Multiple Airlines
Sun 8/99:36 pm
JAX
- DSM
Nonstop2h 43m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$185
This Trip.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:12 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Thu 8/139:36 pm
JAX
- DSM
Nonstop2h 43m
Allegiant Air
Deal found 7/9![Allegiant Air logo]()
$83
This Super.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:12 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Sun 8/169:36 pm
JAX
- DSM
Nonstop2h 43m
Allegiant Air
Deal found 7/11![Allegiant Air logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:12 pm
DSM
- JAX
Nonstop2h 34m
Multiple Airlines
Thu 8/1310:33 pm
JAX
- DSM
1 stop19h 44m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:12 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Fri 8/1410:12 am
JAX
- DSM
2 stops14h 02m
Allegiant Air
Deal found 7/13![Allegiant Air logo]()
$215
One-way flights from Des Moines to JacksonvilleSearch for one-way flight options from Des Moines to Jacksonville. Find affordable one-way fares based on user searches. Data last updated July 14, 2026.
Search for one-way flight options from Des Moines to Jacksonville. Find affordable one-way fares based on user searches. Data last updated July 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/193:59 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Deal found 7/9![Allegiant Air logo]()
$60
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:40 pm
DSM
- JAX
1 stop21h 30m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:40 pm
DSM
- JAX
1 stop22h 24m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/194:57 pm
DSM
- JAX
2 stops38h 41m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/182:20 pm
DSM
- JAX
2 stops27h 18m
Allegiant Air
Deal found 7/9![Allegiant Air logo]()
$389
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:00 am
DSM
- JAX
1 stop5h 27m
United Airlines
Deal found 7/10![United Airlines logo]()
$439
This deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:00 am
DSM
- JAX
1 stop5h 27m
United Airlines
Deal found 7/12![United Airlines logo]()
$514
Find flight deals from Des Moines to Jacksonville
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Jacksonville (JAX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $83 (Trip.com) |
One-way from | $60 (Kiwi.com) |
Popular in | March |
Cheapest in | October |
Average price | $115 |
Good round-trip deal | $86 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 14, 2026.
Use the filters below to find and compare flights from Des Moines to Jacksonville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Thu 8/13
5:12 pm-8:46 pm
Nonstop2h 34m
Jacksonville
Fri 8/14
6:29 pm-10:09 am
3 stops40h 40m
$233
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Fri 10/2
6:54 pm-11:59 pm
1 stop4h 05m
Jacksonville
Tue 10/6
5:33 pm-10:34 pm
1 stop6h 01m
$275
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Wed 9/16
2:40 pm-9:15 pm
1 stop5h 35m
Jacksonville
Wed 9/23
5:25 pm-9:55 pm
1 stop5h 30m
$275
Quickest round-trip
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Thu 10/1
6:54 pm-11:59 pm
1 stop4h 05m
Jacksonville
Mon 10/5
6:59 pm-10:29 pm
1 stop4h 30m
$275
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Thu 9/10
5:40 am-3:15 pm
2 stops8h 35m
Jacksonville
Mon 9/14
7:00 am-11:25 am
1 stop5h 25m
$280
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Mon 8/24
5:40 am-1:20 pm
2 stops6h 40m
Jacksonville
Fri 8/28
2:00 pm-10:10 pm
2 stops9h 10m
$325
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Mon 8/24
1:35 pm-9:46 pm
1 stop7h 11m
Jacksonville
Fri 8/28
5:00 pm-10:30 pm
1 stop6h 30m
$380
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Wed 8/26
7:15 am-4:45 pm
2 stops8h 30m
Jacksonville
Sun 8/30
3:00 pm-10:50 pm
2 stops8h 50m
$390
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Thu 8/13
5:40 am-3:15 pm
2 stops8h 35m
Jacksonville
Fri 8/14
2:00 pm-10:10 pm
2 stops9h 10m
$390
Des MoinesJacksonville
DSM - JAX
DSMJAX
Des Moines
Thu 9/10
8:00 am-8:54 pm
2 stops11h 54m
Jacksonville
Sat 9/19
9:25 am-5:28 pm
2 stops9h 03m
$407
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Jacksonville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Jacksonville in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Jacksonville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Jacksonville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Jacksonville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Jacksonville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Jacksonville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Jacksonville
Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Des Moines with our price prediction graph.
DSM-JAX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Jacksonville
Prices
More
How far ahead should I book a flight from Des Moines to Jacksonville?
The price you pay for your flight from Des Moines to Jacksonville may vary depending on when you book. For the best chance of a lower fare, look to book 48 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to Jacksonville?
Currently, October is the cheapest month in which you can book a flight from Des Moines to Jacksonville (average of $90). Flying from Des Moines to Jacksonville in March is currently the most expensive (average of $455). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Jacksonville?
What’s the top layover airport for flights from Des Moines to Jacksonville?
Share of 1-stop round-trip flights from Des Moines to Jacksonville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Dallas (DFW) – chosen by Cheapflights users on 50% of 1-stop itineraries from Des Moines to Jacksonville on Cheapflights.
What’s the cheapest layover airport for flights from Des Moines to Jacksonville?
Average round-trip fare for 1-stop flights from Des Moines to Jacksonville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $276.
What’s the fastest layover option from Des Moines to Jacksonville?
Shortest average travel time for 1-stop one-way flights from Des Moines to Jacksonville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via St. Louis (STL) have the shortest average one-way travel time for 1-stop routes: 4h 00m.
Which airport typically offers the quickest layover for flights from Des Moines to Jacksonville?
Average layover duration for 1-stop one-way flights from Des Moines to Jacksonville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via St. Louis (STL) offer the fastest connection on this route, with an average layover time of 1h 15m.
Reviews of airlines servicing Jacksonville
Get insights into the airlines that provide service to Jacksonville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Jacksonville. Reviews last updated July 14, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to Jacksonville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Book flights to Jacksonville if you plan to visit one of these locationsJacksonville Beach
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Top 5 airlines flying from Des Moines to Jacksonville
Discover the top 5 airlines that operate flights from Des Moines to Jacksonville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$64 | Average$101 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$180 | Average$392 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$203 | Average$406 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$222 | Average$406 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$296 | Average$452 | FlexibilityNo cancel fee | On-time63% |