$82+ Cheap flights from Myrtle Beach to Indianapolis (MYR - IND)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/1. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — IND
Aug 21 — Aug 281
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Myrtle Beach to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Indianapolis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Myrtle Beach to IndianapolisExplore the most affordable flight options available from Myrtle Beach to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.
Explore the most affordable flight options available from Myrtle Beach to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.
This CheapOair deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:46 am
MYR
- IND
Nonstop1h 46m
Allegiant Air
Sat 8/86:15 am
IND
- MYR
Nonstop1h 46m
Allegiant Air
Deal found 7/18![Allegiant Air logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:51 am
MYR
- IND
Nonstop1h 54m
Multiple Airlines
Mon 8/1012:20 pm
IND
- MYR
2 stops21h 30m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:46 am
MYR
- IND
Nonstop1h 46m
Multiple Airlines
Sat 8/87:38 pm
IND
- MYR
1 stop13h 17m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:25 pm
MYR
- IND
1 stop17h 22m
Multiple Airlines
Mon 10/512:39 pm
IND
- MYR
2 stops21h 26m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:35 am
MYR
- IND
2 stops27h 09m
Multiple Airlines
Mon 10/192:46 pm
IND
- MYR
1 stop19h 04m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:35 am
MYR
- IND
2 stops27h 09m
Multiple Airlines
Tue 10/202:16 pm
IND
- MYR
1 stop21h 28m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$265
Best flights from Myrtle Beach to IndianapolisDiscover carefully curated flight deals from Myrtle Beach to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 22, 2026.
Discover carefully curated flight deals from Myrtle Beach to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 22, 2026.
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:15 pm
MYR
- IND
1 stop5h 58m
American Airlines
Thu 8/204:12 pm
IND
- MYR
1 stop4h 47m
American Airlines
Deal found 7/22![American Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:55 pm
MYR
- IND
2 stops8h 45m
Southwest
Mon 10/55:10 am
IND
- MYR
2 stops10h 10m
Southwest
Deal found 7/21![Southwest logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/52:42 pm
MYR
- IND
1 stop19h 21m
Multiple Airlines
Thu 8/67:38 pm
IND
- MYR
1 stop12h 12m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:08 pm
MYR
- IND
1 stop6h 19m
American Airlines
Mon 12/1410:20 am
IND
- MYR
1 stop3h 39m
American Airlines
Deal found 7/17![American Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:25 pm
MYR
- IND
2 stops7h 15m
Southwest
Mon 12/146:50 am
IND
- MYR
2 stops6h 25m
Southwest
Deal found 7/17![Southwest logo]()
$326
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:50 am
MYR
- IND
2 stops8h 05m
Southwest
Mon 8/249:10 am
IND
- MYR
1 stop4h 40m
Southwest
Deal found 7/21![Southwest logo]()
$334
This American Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:30 pm
MYR
- IND
1 stop3h 50m
American Airlines
Mon 9/148:06 am
IND
- MYR
1 stop3h 14m
American Airlines
Deal found 7/17![American Airlines logo]()
$340
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:55 pm
MYR
- IND
2 stops8h 40m
Southwest
Sat 8/226:50 am
IND
- MYR
1 stop4h 15m
Southwest
Deal found 7/19![Southwest logo]()
$345
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/111:40 pm
MYR
- IND
2 stops11h 00m
Southwest
Mon 12/146:50 am
IND
- MYR
2 stops6h 25m
Southwest
Deal found 7/17![Southwest logo]()
$350
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:30 am
MYR
- IND
2 stops8h 50m
Southwest
Thu 8/276:45 am
IND
- MYR
2 stops7h 05m
Southwest
Deal found 7/21![Southwest logo]()
$367
Last-minute flights from Myrtle Beach to IndianapolisDiscover last-minute flight deals from Myrtle Beach to Indianapolis. Data last updated July 22, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Indianapolis. Data last updated July 22, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:46 am
MYR
- IND
Nonstop1h 46m
Allegiant Air
Sat 8/86:15 am
IND
- MYR
Nonstop1h 46m
Allegiant Air
Deal found 7/18![Allegiant Air logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:46 am
MYR
- IND
Nonstop1h 46m
Multiple Airlines
Sat 8/87:38 pm
IND
- MYR
1 stop13h 17m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:51 am
MYR
- IND
Nonstop1h 54m
Multiple Airlines
Mon 8/1012:20 pm
IND
- MYR
2 stops21h 30m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$214
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:15 pm
MYR
- IND
1 stop5h 58m
American Airlines
Thu 8/204:12 pm
IND
- MYR
1 stop4h 47m
American Airlines
Deal found 7/22![American Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:30 pm
MYR
- IND
1 stop6h 55m
Southwest
Wed 8/2612:15 pm
IND
- MYR
1 stop6h 55m
Southwest
Deal found 7/20![Southwest logo]()
$276
One-way flights from Myrtle Beach to IndianapolisSearch for one-way flight options from Myrtle Beach to Indianapolis. Find affordable one-way fares based on user searches. Data last updated July 22, 2026.
Search for one-way flight options from Myrtle Beach to Indianapolis. Find affordable one-way fares based on user searches. Data last updated July 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/209:07 pm
MYR
- IND
2 stops20h 19m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:07 pm
MYR
- IND
2 stops20h 19m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$129
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:21 pm
MYR
- IND
1 stop5h 14m
United Airlines
Deal found 7/21![United Airlines logo]()
$136
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:30 pm
MYR
- IND
1 stop6h 55m
Southwest
Deal found 7/20![Southwest logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:53 pm
MYR
- IND
2 stops25h 33m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$142
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:25 pm
MYR
- IND
2 stops8h 20m
Southwest
Deal found 7/21![Southwest logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:44 pm
MYR
- IND
3 stops44h 42m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/92:58 pm
MYR
- IND
1 stop19h 00m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$188
Find flight deals from Myrtle Beach to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $82 (CheapOair) |
Popular in | August |
Cheapest in | April |
Average price | $358 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachIndianapolis
MYR - IND
MYRIND
Myrtle Beach Intl
Wed 8/19
5:15 pm-11:13 pm
1 stop5h 58m
Indianapolis
Thu 8/20
4:12 pm-8:59 pm
1 stop4h 47m
$271
Myrtle BeachIndianapolis
MYR - IND
MYRIND
Myrtle Beach Intl
Thu 10/1
3:55 pm-12:40 am
2 stops8h 45m
Indianapolis
Mon 10/5
5:10 am-3:20 pm
2 stops10h 10m
$281
Myrtle BeachIndianapolis
MYR - IND
MYRIND
Myrtle Beach Intl
Thu 12/10
6:08 pm-12:27 am
1 stop6h 19m
Indianapolis
Mon 12/14
10:20 am-1:59 pm
1 stop3h 39m
$293
Myrtle BeachIndianapolis
MYR - IND
MYRIND
Myrtle Beach Intl
Thu 12/10
3:25 pm-10:40 pm
2 stops7h 15m
Indianapolis
Mon 12/14
6:50 am-1:15 pm
2 stops6h 25m
$326
Myrtle BeachIndianapolis
MYR - IND
MYRIND
Myrtle Beach Intl
Fri 8/21
10:50 am-6:55 pm
2 stops8h 05m
Indianapolis
Mon 8/24
9:10 am-1:50 pm
1 stop4h 40m
$334
Quickest round-trip
Myrtle BeachIndianapolis
MYR - IND
MYRIND
Myrtle Beach Intl
Sun 9/13
8:30 pm-12:20 am
1 stop3h 50m
Indianapolis
Mon 9/14
8:06 am-11:20 am
1 stop3h 14m
$340
Myrtle BeachIndianapolis
MYR - IND
MYRIND
Myrtle Beach Intl
Fri 8/21
1:55 pm-10:35 pm
2 stops8h 40m
Indianapolis
Sat 8/22
6:50 am-11:05 am
1 stop4h 15m
$345
Myrtle BeachIndianapolis
MYR - IND
MYRIND
Myrtle Beach Intl
Fri 12/11
1:40 pm-12:40 am
2 stops11h 00m
Indianapolis
Mon 12/14
6:50 am-1:15 pm
2 stops6h 25m
$350
Myrtle BeachIndianapolis
MYR - IND
MYRIND
Myrtle Beach Intl
Sun 8/23
7:30 am-4:20 pm
2 stops8h 50m
Indianapolis
Thu 8/27
6:45 am-1:50 pm
2 stops7h 05m
$367
Myrtle BeachIndianapolis
MYR - IND
MYRIND
Myrtle Beach Intl
Wed 8/5
2:42 pm-10:03 am
1 stop19h 21m
Indianapolis
Thu 8/6
7:38 pm-7:50 am
1 stop12h 12m
$372
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Indianapolis in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Myrtle Beach with our price prediction graph.
MYR-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Indianapolis
What is the cheapest time of day to fly from MYR to IND?
Find hourly flight availability from Myrtle Beach to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 22, 2026.
When flying from Myrtle Beach to Indianapolis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Myrtle Beach to Indianapolis?
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated July 22, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Myrtle Beach to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Muncie
Greenwood
Kokomo
Plainfield
Fishers
Franklin
Mooresville
Anderson
Crawfordsville
Carmel
Noblesville
Bloomington
Speedway
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Indianapolis flight routes
Other flight options
Other flights from Myrtle Beach
Popular flights
Alternative routes for Myrtle Beach to Indianapolis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indianapolis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Myrtle Beach to Indianapolis by cabin class
Find flights from Myrtle Beach to Indianapolis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 22, 2026.
Myrtle Beach and Indianapolis flights
Browse other Myrtle Beach and Indianapolis flight options. Last updated on July 22, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on July 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Myrtle Beach to Indianapolis
Discover the top 2 airlines that operate flights from Myrtle Beach to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$274 | Average$386 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$310 | Average$382 | FlexibilityNo cancel fee | On-timeN/A |