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$87+ Cheap flights from Myrtle Beach to Indianapolis (MYR - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — IND
Oct 25 — Nov 11
Sat 10/25
Sat 11/1
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 25, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$192
(Cheapflightsfares)

One-way from

$87
(Cheapflightsfares)

Popular in

March

Cheapest in

August

Average price

$308

Good one-way deal

$119 or less
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
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From Myrtle Beach Intl to Indianapolis
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One-way flight from Myrtle Beach Intl to Indianapolis
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Highest demand for flights based on searches. 33% potential increase in price ($192 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($35 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a one-way flight from Myrtle Beach Intl to Indianapolis.
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Find flight deals from Myrtle Beach to Indianapolis

Cheapest flights from Myrtle Beach to Indianapolis
Explore the most affordable flight options available from Myrtle Beach to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:46 amMYR - IND
1 stop11h 10mSpirit Airlines
Sun 11/161:57 pmIND - MYR
1 stop5h 38mSpirit Airlines
Deal found 9/24$192
This Cheapflightsfares deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:20 pmMYR - IND
1 stop5h 51mSpirit Airlines
Mon 10/1310:43 amIND - MYR
1 stop7h 01mSpirit Airlines
Deal found 9/24$224
This Cheapflightsfares deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2212:11 pmMYR - IND
1 stop4h 56mSpirit Airlines
Sun 10/2610:43 amIND - MYR
1 stop8h 15mSpirit Airlines
Deal found 9/25$230
This CheapOair deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/611:46 amMYR - IND
1 stop11h 10mSpirit Airlines
Sun 11/91:57 pmIND - MYR
1 stop5h 38mSpirit Airlines
Deal found 9/23$233
This Cheapflightsfares deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2712:23 pmMYR - IND
1 stop6h 51mSpirit Airlines
Mon 9/295:45 amIND - MYR
1 stop6h 12mSpirit Airlines
Deal found 9/23$262
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/228:14 amMYR - IND
1 stop8h 53mMultiple Airlines
Sun 10/2610:06 pmIND - MYR
2 stops14h 42mMultiple Airlines
Deal found 9/25$263
This Cheapflightsfares deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:20 pmMYR - IND
1 stop5h 51mSpirit Airlines
Mon 9/295:45 amIND - MYR
1 stop6h 12mSpirit Airlines
Deal found 9/23$287
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:43 pmMYR - IND
2 stops21h 46mMultiple Airlines
Fri 10/315:15 amIND - MYR
1 stop18h 42mMultiple Airlines
Deal found 9/24$289
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:59 amMYR - IND
1 stop14h 33mMultiple Airlines
Sun 11/910:21 pmIND - MYR
2 stops12h 20mMultiple Airlines
Deal found 9/23$291
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/812:20 pmMYR - IND
1 stop5h 37mDelta
Tue 11/116:48 pmIND - MYR
1 stop4h 56mDelta
Deal found 9/23$297
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:05 amMYR - IND
2 stops6h 51mAmerican Airlines
Tue 11/116:00 amIND - MYR
1 stop3h 37mAmerican Airlines
Deal found 9/23$302

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 25, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Indianapolis that are best for you.

Fly from

Myrtle Beach

Fly to

Indianapolis

Route

Depart

Return

Price

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 11/13

11:46 am-10:56 pm

1 stop11h 10m

Indianapolis

Sun 11/16

1:57 pm-7:35 pm

1 stop5h 38m

$192

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 11/14

11:46 am-10:56 pm

1 stop11h 10m

Indianapolis

Sun 11/16

1:57 pm-7:35 pm

1 stop5h 38m

$192

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 10/22

8:14 am-5:07 pm

1 stop8h 53m

Indianapolis

Sun 10/26

10:06 pm-12:48 pm

2 stops14h 42m

$263

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 10/24

6:43 pm-4:29 pm

2 stops21h 46m

Indianapolis

Fri 10/31

5:15 am-11:57 pm

1 stop18h 42m

$289

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 11/6

9:59 am-12:32 am

1 stop14h 33m

Indianapolis

Sun 11/9

10:21 pm-10:41 am

2 stops12h 20m

$291

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Sat 11/8

12:20 pm-5:57 pm

1 stop5h 37m

Indianapolis

Tue 11/11

6:48 pm-11:44 pm

1 stop4h 56m

$297

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Sat 11/8

6:05 am-12:56 pm

2 stops6h 51m

Indianapolis

Tue 11/11

6:00 am-9:37 am

1 stop3h 37m

$302

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 10/16

9:05 pm-9:48 am

1 stop12h 43m

Indianapolis

Sat 10/18

5:47 pm-3:04 pm

2 stops21h 17m

$310

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 10/1

7:36 pm-5:09 pm

1 stop21h 33m

Indianapolis

Sat 10/4

9:27 pm-8:49 am

1 stop11h 22m

$317

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 10/17

1:12 pm-9:14 pm

1 stop8h 02m

Indianapolis

Sun 10/19

10:43 am-6:43 pm

1 stop8h 00m

$347

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/24

Showing 1-10 of 16 results
1
2

Compare providers for flights from Myrtle Beach to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Indianapolis in September.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Indianapolis

What is the cheapest month to book a flight from Myrtle Beach to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Indianapolis (average of $285). Flying from Myrtle Beach to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to IND?

Find hourly flight availability from Myrtle Beach to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 25, 2025.

When flying from Myrtle Beach to Indianapolis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated September 25, 2025.
Read reviews from past customers who have flown Delta, American Airlines, and Spirit Airlines from Myrtle Beach to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,973 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Spirit Airlines
6.3
Okay
8,045 reviews
Delta
8.0
Very good
7,973 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Indianapolis?

    There are many flights that can get you from Myrtle Beach to Indianapolis in 11h 10m. Fly via Spirit Airlines to get the fastest option. The distance from Myrtle Beach to Indianapolis is about 583 mi.

  • What are the cheapest airlines flying from Myrtle Beach to Indianapolis round-trip?

    Our cheapest airline available from Myrtle Beach to Indianapolis is Spirit Airlines. Our recent data shows that you can find tickets from as low as $149 on this airline. Additional options worth looking into are American Airlines and Delta, starting at $271 and $282 round-trip. Spirit Airlines is currently priced 60% below the average price you’ll pay for this route.

  • What are the cheapest flights from Myrtle Beach to Indianapolis?

    Looking at all options, your cheapest flight can be booked for $94. While the most popular route (Myrtle Beach Intl - Indianapolis) can be booked for $192 on average, our data indicates $119 when flying from Myrtle Beach to Indianapolis.

  • Can I find deals for flights from Myrtle Beach to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Indianapolis.

  • Can I find deals for business class flights from Myrtle Beach to Indianapolis?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Indianapolis (average of $285). Flying from Myrtle Beach to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Noblesville
Fishers
Anderson
Kokomo
Greenwood
Bloomington
Franklin
Plainfield
Carmel
Crawfordsville
Speedway

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Alternative routes for Myrtle Beach to Indianapolis

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Top 3 airlines flying from Myrtle Beach to Indianapolis

Discover the top 3 airlines that operate flights from Myrtle Beach to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$149Average$209FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$271Average$384FlexibilityNo cancel feeOn-time71%
DeltaCheapest$282Average$386FlexibilityNo cancel feeOn-timeN/A

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