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$87+ Cheap flights from Myrtle Beach to Indianapolis (MYR - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — IND
Aug 18 — Aug 251
Mon 8/18
Mon 8/25
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 13, 2025.

Round-trip from

$166
(Cheapflightsfares)

One-way from

$87
(Priceline)

Popular in

March

Cheapest in

August

Average price

$210

Good one-way deal

$43 or less
From Myrtle Beach Intl to Indianapolis
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One-way flight from Myrtle Beach Intl to Indianapolis
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Highest demand for flights based on searches. 32% potential increase in price ($183 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($34 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a one-way flight from Myrtle Beach Intl to Indianapolis.
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Find flight deals from Myrtle Beach to Indianapolis

Cheapest flights from Myrtle Beach to Indianapolis
Explore the most affordable flight options available from Myrtle Beach to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2025.

This Priceline deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/269:00 amMYR - IND
1 stop5h 07mSpirit Airlines
Sat 8/3011:40 amIND - MYR
1 stop8h 29mSpirit Airlines
Deal found 8/10$168
This Cheapflightsfares deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/281:45 pmMYR - IND
1 stop6h 20mSpirit Airlines
Tue 9/95:45 amIND - MYR
1 stop6h 44mSpirit Airlines
Deal found 8/11$172
This FlightHub deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2212:23 pmMYR - IND
1 stop7h 50mSpirit Airlines
Thu 9/255:00 amIND - MYR
1 stop18h 14mSpirit Airlines
Deal found 8/12$186
This FlightHub deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:20 pmMYR - IND
1 stop5h 51mSpirit Airlines
Mon 10/139:09 pmIND - MYR
1 stop12h 17mSpirit Airlines
Deal found 8/11$190
This Cheapflightsfares deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/45:20 pmMYR - IND
1 stop5h 51mSpirit Airlines
Fri 9/55:45 amIND - MYR
1 stop6h 12mSpirit Airlines
Deal found 8/12$191
This FlightHub deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/39:00 amMYR - IND
1 stop5h 07mSpirit Airlines
Mon 9/85:45 amIND - MYR
1 stop6h 12mSpirit Airlines
Deal found 8/11$196
This FlightHub deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/57:17 pmMYR - IND
1 stop14h 01mSpirit Airlines
Mon 9/85:45 amIND - MYR
1 stop6h 12mSpirit Airlines
Deal found 8/11$202
This Mytrip deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/197:17 pmMYR - IND
1 stop14h 01mSpirit Airlines
Sun 9/215:45 amIND - MYR
1 stop10h 40mSpirit Airlines
Deal found 8/12$215
This Mytrip deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:00 amMYR - IND
2 stops11h 09mSpirit Airlines
Mon 9/155:45 amIND - MYR
1 stop6h 12mSpirit Airlines
Deal found 8/12$216

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Indianapolis that are best for you.

Fly from

Myrtle Beach

Fly to

Indianapolis

Route

Depart

Return

Price

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 8/28

1:45 pm-8:05 pm

1 stop6h 20m

Indianapolis

Tue 9/9

11:55 am-7:46 pm

1 stop7h 51m

$166

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Tue 8/26

9:00 am-2:07 pm

1 stop5h 07m

Indianapolis

Sat 8/30

11:40 am-8:09 pm

1 stop8h 29m

$168

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 10/2

1:11 pm-6:18 pm

1 stop5h 07m

Indianapolis

Mon 10/13

11:40 am-5:48 pm

1 stop6h 08m

$172

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Mon 9/22

12:23 pm-8:13 pm

1 stop7h 50m

Indianapolis

Thu 9/25

5:45 am-4:25 pm

1 stop10h 40m

$172

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 9/4

5:20 pm-11:11 pm

1 stop5h 51m

Indianapolis

Mon 9/8

11:10 am-12:29 pm

1 stop25h 19m

$190

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 9/4

5:20 pm-11:11 pm

1 stop5h 51m

Indianapolis

Fri 9/5

5:45 am-11:57 am

1 stop6h 12m

$191

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 9/26

12:23 pm-8:13 pm

1 stop7h 50m

Indianapolis

Sun 9/28

11:10 am-4:25 pm

1 stop5h 15m

$191

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 10/15

12:06 pm-5:07 pm

1 stop5h 01m

$87

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Sun 10/12

7:39 pm-8:04 pm

1 stop24h 25m

$122

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Mon 9/1

8:45 am-6:01 pm

1 stop9h 16m

$204

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/12

Showing 1-10 of 12 results
1
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Best time to book a flight from Myrtle Beach to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Indianapolis

What is the cheapest month to book a flight from Myrtle Beach to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Indianapolis (average of $297). Flying from Myrtle Beach to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to IND?

Find hourly flight availability from Myrtle Beach to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 13, 2025.

When flying from Myrtle Beach to Indianapolis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated August 13, 2025.
Read reviews from past customers who have flown Delta, American Airlines, and Spirit Airlines from Myrtle Beach to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,979 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Spirit Airlines
6.3
Okay
8,048 reviews
Delta
8.0
Very good
7,979 reviews

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Myrtle Beach to Indianapolis round-trip?

    Our cheapest airline available from Myrtle Beach to Indianapolis is Spirit Airlines. Our recent data shows that you can find tickets from as low as $166 on this airline. Spirit Airlines is currently priced 56% below the average price you’ll pay for this route.

  • What are the cheapest flights from Myrtle Beach to Indianapolis?

    Looking at all options, your cheapest flight can be booked for $38. While the most popular route (Myrtle Beach Intl - Indianapolis) can be booked for $172 on average our data indicates $117 when flying from Myrtle Beach to Indianapolis.

  • Can I find deals for flights from Myrtle Beach to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Indianapolis.

  • Can I find deals for business class flights from Myrtle Beach to Indianapolis?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Indianapolis (average of $297). Flying from Myrtle Beach to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Greenwood
Bloomington
Muncie
Noblesville
Fishers
Terre Haute
Anderson
Kokomo
Franklin
Plainfield
Carmel
Crawfordsville
Shelbyville
Speedway

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Myrtle Beach to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Myrtle Beach to Indianapolis

Discover the top 3 airlines that operate flights from Myrtle Beach to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$149Average$209FlexibilityNo cancel feeOn-time65%
DeltaCheapest$237Average$386FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$263Average$383FlexibilityNo cancel feeOn-time71%

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