HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Indianapolis

$103+ Cheap flights from Myrtle Beach to Indianapolis (MYR - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — IND
Apr 25 — May 21
Sat 4/25
Sat 5/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Myrtle Beach to Indianapolis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Myrtle Beach to Indianapolis

Cheapest flights from Myrtle Beach to Indianapolis
Explore the most affordable flight options available from Myrtle Beach to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:50 am
MYR
-
IND
Nonstop1h 49m
Allegiant Air
Sat 6/276:15 am
IND
-
MYR
Nonstop1h 45m
Allegiant Air
Deal found 3/24$105
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:55 pm
MYR
-
IND
1 stop28h 37m
Multiple Airlines
Sun 4/2612:12 pm
IND
-
MYR
2 stops8h 54m
Multiple Airlines
Deal found 3/25$227
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:52 am
MYR
-
IND
1 stop10h 40m
Multiple Airlines
Sun 4/2612:12 pm
IND
-
MYR
2 stops8h 54m
Multiple Airlines
Deal found 3/25$235
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:02 pm
MYR
-
IND
1 stop5h 39m
Delta
Tue 4/286:00 am
IND
-
MYR
1 stop3h 40m
Delta
Deal found 3/24$237
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:15 pm
MYR
-
IND
1 stop4h 47m
United Airlines
Tue 4/286:00 am
IND
-
MYR
2 stops11h 02m
United Airlines
Deal found 3/24$242
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:33 pm
MYR
-
IND
1 stop14h 21m
Multiple Airlines
Sat 7/116:15 am
IND
-
MYR
Nonstop1h 46m
Multiple Airlines
Deal found 3/23$243
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:50 am
MYR
-
IND
Nonstop1h 49m
Multiple Airlines
Sat 6/2712:18 pm
IND
-
MYR
1 stop9h 07m
Multiple Airlines
Deal found 3/24$254
This Super.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:52 am
MYR
-
IND
1 stop12h 05m
Spirit Airlines
Mon 5/186:00 am
IND
-
MYR
1 stop9h 10m
Spirit Airlines
Deal found 3/23$261
This Priceline deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1311:52 am
MYR
-
IND
1 stop8h 57m
Spirit Airlines
Sat 5/166:00 am
IND
-
MYR
1 stop4h 55m
Spirit Airlines
Deal found 3/21$262

Find flight deals from Myrtle Beach to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$105
(Kiwi.com)

One-way from

$103
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$486

Good one-way deal

$119 or less
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
Search Deals
From Myrtle Beach Intl to Indianapolis
Search Deals
One-way flight from Myrtle Beach Intl to Indianapolis
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($68 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a one-way flight from Myrtle Beach Intl to Indianapolis.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Tue 4/21

7:02 pm-12:41 am

1 stop5h 39m

Indianapolis

Tue 4/28

6:00 am-9:40 am

1 stop3h 40m

$237

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Tue 4/21

3:15 pm-8:02 pm

1 stop4h 47m

Indianapolis

Tue 4/28

6:00 am-5:02 pm

2 stops11h 02m

$242

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 5/13

11:52 am-8:49 pm

1 stop8h 57m

Indianapolis

Sat 5/16

6:00 am-10:55 am

1 stop4h 55m

$262

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 5/13

8:44 pm-9:45 pm

2 stops25h 01m

Indianapolis

Sat 5/16

6:00 am-10:55 am

1 stop4h 55m

$332

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 5/13

2:10 pm-9:05 pm

2 stops6h 55m

Indianapolis

Sat 5/16

6:45 am-4:10 pm

2 stops9h 25m

$347

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Tue 4/21

5:55 pm-11:58 pm

3 stops30h 03m

Indianapolis

Tue 4/28

8:00 am-8:41 am

3 stops24h 41m

$351

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Sat 5/23

11:52 am-8:49 pm

1 stop8h 57m

Indianapolis

Mon 5/25

6:00 am-8:58 pm

1 stop14h 58m

$356

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 4/16

3:15 pm-8:09 pm

1 stop4h 54m

Indianapolis

Mon 4/20

7:00 am-2:17 pm

1 stop7h 17m

$363

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Sun 4/5

12:05 pm-11:23 am

2 stops23h 18m

Indianapolis

Tue 4/7

5:45 am-5:33 pm

1 stop11h 48m

$392

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 4/22

11:00 am-4:52 pm

1 stop5h 52m

Indianapolis

Sun 4/26

9:00 am-2:17 pm

1 stop5h 17m

$392

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/24

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Myrtle Beach to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Indianapolis in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Indianapolis

What is the cheapest month to book a flight from Myrtle Beach to Indianapolis?

Currently, October is the cheapest month in which you can book a flight from Myrtle Beach to Indianapolis (average of $40). Flying from Myrtle Beach to Indianapolis in January is currently the most expensive (average of $105). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Myrtle Beach to Indianapolis?

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated March 26, 2026.
Read reviews from past customers who have flown Delta,American Airlines, andSpirit Airlines from Myrtle Beach to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,332 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,332 reviews
Delta
7.9
Good
8,332 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,496 reviews
Delta
7.9
Good
8,332 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,546 reviews
Delta
7.9
Good
8,332 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Indianapolis?

    There are many flights that can get you from Myrtle Beach to Indianapolis in 4h 47m. Fly via Delta, United Airlines, or Spirit Airlines to get the fastest option. The distance from Myrtle Beach to Indianapolis is about 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Myrtle Beach to Indianapolis round-trip?

    Our cheapest airline available from Myrtle Beach to Indianapolis is Spirit Airlines. Our recent data shows that you can find tickets from as low as $83 on this airline. Additional options worth looking into are American Airlines and Delta, starting at $271 and $341 round-trip. Spirit Airlines is currently priced 75% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Myrtle Beach to Indianapolis one-way?

    For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $38. Users have also found prices from $75 and $127 on Spirit Airlines and Delta, respectively.

  • What are the cheapest flights from Myrtle Beach to Indianapolis?

    Looking at all options, your cheapest flight can be booked for $94. While the most popular route (Myrtle Beach Intl - Indianapolis) can be booked for $105 on average, our data indicates $119 when flying from Myrtle Beach to Indianapolis.

  • Can I find deals for flights from Myrtle Beach to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Indianapolis.

  • Can I find deals for business class flights from Myrtle Beach to Indianapolis?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Indianapolis?

    Currently, October is the cheapest month in which you can book a flight from Myrtle Beach to Indianapolis (average of $40). Flying from Myrtle Beach to Indianapolis in January is currently the most expensive (average of $105). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Fishers
Noblesville
Kokomo
Greenwood
Plainfield
Mooresville
Anderson
Franklin
Carmel
Crawfordsville
Bloomington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Myrtle Beach to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to O'Hare Intl flights
Charleston to O'Hare Intl flights
Greenville to O'Hare Intl flights
Columbia to O'Hare Intl flights
Charleston to Midway flights
Savannah to O'Hare Intl flights
Charlotte to Cincinnati flights
Charlotte to Indianapolis flights
Charlotte to Louisville flights
Myrtle Beach to O'Hare Intl flights
Charleston to Indianapolis flights
Columbia to Midway flights
Greenville to Midway flights
Savannah to Midway flights
Greenville to Indianapolis flights
Hilton Head Island to O'Hare Intl flights
Columbia to Indianapolis flights
Myrtle Beach to Midway flights
Charlotte to Dayton flights
Augusta to O'Hare Intl flights
Savannah to Indianapolis flights
Savannah to Louisville flights
Charleston to Louisville flights
Savannah to South Bend flights
Savannah to Dayton flights
Columbia to Louisville flights
Charlotte to South Bend flights
Charleston to Dayton flights
Charleston to South Bend flights
Savannah to Cincinnati flights
Myrtle Beach to Cincinnati flights
Charleston to Cincinnati flights
Charlotte to Kalamazoo flights
Charlotte to Rockford flights
Augusta to Midway flights
Myrtle Beach to Dayton flights
Columbia to Cincinnati flights
Charleston to Rockford flights
Myrtle Beach to Louisville flights
Greenville to Cincinnati flights
Greenville to Louisville flights
Augusta to Indianapolis flights
Myrtle Beach to South Bend flights
Charlotte to Fort Wayne flights
Greenville to Fort Wayne flights
Charlotte to Evansville flights
Greenville to Evansville flights
Columbia to Dayton flights

Top 3 airlines flying from Myrtle Beach to Indianapolis

Discover the top 3 airlines that operate flights from Myrtle Beach to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$83Average$173FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$271Average$384FlexibilityNo cancel feeOn-time71%
DeltaCheapest$341Average$477FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.