$127+ Cheap flights from Myrtle Beach to Indianapolis (MYR - IND)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — IND
Oct 2 — Oct 91
Round-trip
1 adult, Economy
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Find cheap flights from Myrtle Beach to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Indianapolis
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Cheapest flights from Myrtle Beach to IndianapolisExplore the most affordable flight options available from Myrtle Beach to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
Explore the most affordable flight options available from Myrtle Beach to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:40 am -
1 stop5h 05m
Tue 10/65:30 am -
1 stop4h 15m
Deal found 9/1![Southwest logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:05 pm -
1 stop15h 48m
Tue 11/171:33 pm -
1 stop19h 35m
Deal found 8/28![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:45 am -
2 stops32h 08m
Tue 10/1312:33 pm -
1 stop20h 35m
Deal found 9/1![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:12 pm -
2 stops16h 46m
Mon 10/129:06 pm -
1 stop12h 59m
Deal found 8/31![Multiple Airlines logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:15 am -
1 stop24h 52m
Mon 9/217:48 pm -
2 stops19h 29m
Deal found 8/31![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:12 pm -
2 stops16h 46m
Tue 10/1312:33 pm -
1 stop20h 35m
Deal found 8/31![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:40 pm -
1 stop29h 34m
Wed 10/711:21 am -
1 stop21h 29m
Deal found 8/31![Multiple Airlines logo]()
$350
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:01 pm -
1 stop4h 36m
Mon 10/196:04 am -
1 stop5h 21m
Deal found 8/31![American Airlines logo]()
$351
Best flights from Myrtle Beach to IndianapolisDiscover carefully curated flight deals from Myrtle Beach to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
Discover carefully curated flight deals from Myrtle Beach to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:55 pm -
2 stops8h 15m
Tue 10/63:50 pm -
1 stop3h 40m
Deal found 9/1![Southwest logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/231:48 pm -
1 stop27h 27m
Mon 11/306:10 pm -
1 stop15h 55m
Deal found 8/28![Multiple Airlines logo]()
$387
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:27 am -
1 stop7h 37m
Wed 11/1111:01 am -
1 stop6h 10m
Deal found 8/31![United Airlines logo]()
$424
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:40 am -
2 stops9h 45m
Mon 10/193:10 pm -
1 stop6h 20m
Deal found 8/31![Southwest logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:59 am -
2 stops30h 54m
Mon 9/219:20 pm -
1 stop12h 45m
Deal found 9/2![Multiple Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:20 am -
1 stop4h 05m
Mon 11/3012:10 pm -
2 stops9h 40m
Deal found 8/28![Southwest logo]()
$409
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/151:40 pm -
2 stops10h 35m
Tue 11/178:10 am -
2 stops11h 10m
Deal found 8/28![Southwest logo]()
$412
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:55 pm -
2 stops8h 50m
Tue 10/136:50 am -
2 stops6h 40m
Deal found 8/31![Southwest logo]()
$417
Last-minute flights from Myrtle Beach to IndianapolisDiscover last-minute flight deals from Myrtle Beach to Indianapolis. Data last updated September 2, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Indianapolis. Data last updated September 2, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:15 am -
1 stop24h 52m
Mon 9/217:48 pm -
2 stops19h 29m
Deal found 8/31![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:40 pm -
1 stop29h 34m
Wed 10/711:21 am -
1 stop21h 29m
Deal found 8/31![Multiple Airlines logo]()
$350
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:40 am -
1 stop5h 05m
Tue 10/65:30 am -
1 stop4h 15m
Deal found 9/1![Southwest logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:45 am -
2 stops32h 08m
Tue 10/1312:33 pm -
1 stop20h 35m
Deal found 9/1![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:12 pm -
2 stops16h 46m
Mon 10/129:06 pm -
1 stop12h 59m
Deal found 8/31![Multiple Airlines logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:12 pm -
2 stops16h 46m
Tue 10/1312:33 pm -
1 stop20h 35m
Deal found 8/31![Multiple Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:01 pm -
1 stop4h 36m
Mon 10/196:04 am -
1 stop5h 21m
Deal found 8/31![American Airlines logo]()
$351
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:40 am -
2 stops9h 45m
Mon 10/193:10 pm -
1 stop6h 20m
Deal found 8/31![Southwest logo]()
$356
One-way flights from Myrtle Beach to IndianapolisSearch for one-way flight options from Myrtle Beach to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
Search for one-way flight options from Myrtle Beach to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:03 pm -
2 stops27h 01m
Deal found 8/31![Multiple Airlines logo]()
$127
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:58 pm -
1 stop5h 34m
Deal found 9/2![Delta logo]()
$136
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:15 am -
2 stops8h 45m
Deal found 9/2![Southwest logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:12 pm -
2 stops24h 52m
Deal found 9/1![Multiple Airlines logo]()
$143
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:12 pm -
1 stop4h 25m
Deal found 9/1![American Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/42:46 pm -
1 stop19h 39m
Deal found 8/30![Multiple Airlines logo]()
$155
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1210:08 am -
2 stops11h 59m
Deal found 8/29![United Airlines logo]()
$165
This Southwest deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:40 pm -
1 stop6h 35m
Deal found 8/29![Southwest logo]()
$176
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:00 am -
2 stops10h 45m
Deal found 8/31![Southwest logo]()
$181
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:10 am -
2 stops7h 00m
Deal found 8/31![American Airlines logo]()
$196
Find flight deals from Myrtle Beach to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $271 (Southwest) |
One-way from | $127 (Kiwi.com) |
Popular in | August |
Cheapest in | April |
Average price | $406 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Thu 10/1
3:55 pm-12:10 am
2 stops8h 15m
Indianapolis
Tue 10/6
3:50 pm-7:30 pm
1 stop3h 40m
$276
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Wed 10/14
8:40 am-6:25 pm
2 stops9h 45m
Indianapolis
Mon 10/19
3:10 pm-9:30 pm
1 stop6h 20m
$356
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Mon 11/23
1:48 pm-5:15 pm
1 stop27h 27m
Indianapolis
Mon 11/30
6:10 pm-10:05 am
1 stop15h 55m
$387
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Thu 9/17
11:59 am-6:53 pm
2 stops30h 54m
Indianapolis
Mon 9/21
9:20 pm-10:05 am
1 stop12h 45m
$409
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Mon 11/23
8:20 am-12:25 pm
1 stop4h 05m
Indianapolis
Mon 11/30
12:10 pm-9:50 pm
2 stops9h 40m
$409
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Sun 11/15
1:40 pm-12:15 am
2 stops10h 35m
Indianapolis
Tue 11/17
8:10 am-7:20 pm
2 stops11h 10m
$412
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Fri 10/9
3:55 pm-12:45 am
2 stops8h 50m
Indianapolis
Tue 10/13
6:50 am-1:30 pm
2 stops6h 40m
$417
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Tue 11/10
11:27 am-7:04 pm
1 stop7h 37m
Indianapolis
Wed 11/11
11:01 am-5:11 pm
1 stop6h 10m
$424
Cheapest one-way
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Tue 10/13
4:03 pm-7:04 pm
2 stops27h 01m
$127
Quickest one-way
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Wed 9/30
6:58 pm-12:32 am
1 stop5h 34m
$136
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Indianapolis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Myrtle Beach with our price prediction graph.
MYR-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Indianapolis
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated September 2, 2026.
Read reviews from past customers who have flown American Airlines from Myrtle Beach to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Entertainment
6.8
Crew
7.9
Boarding
7.5
Food
6.4
Overall
7.1
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Comfort
7.2
Entertainment
6.8
Crew
7.9
Boarding
7.5
Food
6.4
Overall
7.1
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Greenwood
Plainfield
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Anderson
Crawfordsville
Carmel
Noblesville
Bloomington
Speedway
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Myrtle Beach and Indianapolis flights
Browse other Myrtle Beach and Indianapolis flight options. Last updated on September 2, 2026.
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Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Myrtle Beach to Indianapolis
Discover the top airline that operate flights from Myrtle Beach to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$270 | Average$387 | FlexibilityNo cancel fee | On-time71% |