Indianapolis

$38+ Cheap flights from Myrtle Beach to Indianapolis (MYR - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/6. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — IND
Jun 4 — Jun 111
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Cheap flight deals from Myrtle Beach to Indianapolis

Cheapest flights from Myrtle Beach to Indianapolis
Explore the most affordable flight options available from Myrtle Beach to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.

This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/263:53 pm
MYR
-
IND
1 stop18h 35m
Multiple Airlines
Sat 8/16:15 am
IND
-
MYR
Nonstop1h 46m
Multiple Airlines
Deal found 5/4$261
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:06 pm
MYR
-
IND
1 stop4h 38m
American Airlines
Tue 6/911:29 am
IND
-
MYR
1 stop4h 03m
American Airlines
Deal found 5/3$271
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:34 am
MYR
-
IND
2 stops11h 31m
United Airlines
Tue 6/96:00 am
IND
-
MYR
1 stop4h 36m
United Airlines
Deal found 5/3$285
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/193:53 pm
MYR
-
IND
1 stop18h 35m
Multiple Airlines
Fri 7/2412:20 pm
IND
-
MYR
2 stops32h 48m
Multiple Airlines
Deal found 5/5$303
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:05 pm
MYR
-
IND
1 stop4h 05m
Southwest
Sun 6/216:05 pm
IND
-
MYR
1 stop3h 25m
Southwest
Deal found 5/3$329
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:30 am
MYR
-
IND
1 stop28h 51m
Spirit Airlines
Wed 5/2012:26 pm
IND
-
MYR
1 stop8h 10m
Spirit Airlines
Deal found 5/1$334
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:30 am
MYR
-
IND
1 stop5h 20m
Southwest
Wed 9/1612:15 pm
IND
-
MYR
1 stop6h 55m
Southwest
Deal found 5/5$336
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:38 am
MYR
-
IND
3 stops24h 27m
Multiple Airlines
Sat 7/116:15 am
IND
-
MYR
Nonstop1h 46m
Multiple Airlines
Deal found 5/1$337
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:00 am
MYR
-
IND
1 stop13h 38m
Multiple Airlines
Mon 5/2512:34 pm
IND
-
MYR
2 stops29h 16m
Multiple Airlines
Deal found 5/1$345

Find flight deals from Myrtle Beach to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$261
(Kiwi.com)

One-way from

$38
(Cheapflightsfares)

Popular in

March

Cheapest in

August

Average price

$287
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
From Myrtle Beach Intl to Indianapolis
One-way flight from Myrtle Beach Intl to Indianapolis
Highest demand for flights based on searches. 10% potential increase in price ($39 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($15 potential savings vs. average RT price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Sun 9/13

7:30 am-4:20 pm

2 stops8h 50m

Indianapolis

Wed 9/16

12:15 pm-7:10 pm

1 stop6h 55m

$341

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Tue 7/7

5:30 pm-12:16 am

1 stop6h 46m

Indianapolis

Sat 7/11

4:33 pm-9:49 pm

1 stop5h 16m

$374

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 7/2

10:35 am-7:50 pm

2 stops9h 15m

Indianapolis

Sun 7/5

5:20 pm-10:45 pm

1 stop5h 25m

$392

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 7/10

2:00 pm-11:25 pm

2 stops9h 25m

Indianapolis

Mon 7/13

1:15 pm-10:45 pm

2 stops9h 30m

$397
Quickest round-trip

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 6/19

8:10 pm-12:15 am

1 stop4h 05m

Indianapolis

Sun 6/21

6:05 pm-9:30 pm

1 stop3h 25m

$397

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Sun 7/19

7:25 am-4:45 pm

2 stops9h 20m

Indianapolis

Fri 7/24

6:45 am-6:35 pm

2 stops11h 50m

$413

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Sun 7/26

7:25 am-4:45 pm

2 stops9h 20m

Indianapolis

Sat 8/1

5:55 am-3:15 pm

2 stops9h 20m

$417

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Tue 7/7

10:25 am-7:15 pm

2 stops8h 50m

Indianapolis

Sat 7/11

7:15 am-6:35 pm

2 stops11h 20m

$443

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 5/28

6:30 pm-11:44 pm

1 stop5h 14m

Indianapolis

Mon 6/1

6:00 am-10:36 am

1 stop4h 36m

$444
Cheapest one-way

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Mon 8/3

9:30 pm-11:05 am

2 stops37h 35m

$120

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/3

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Compare providers for flights from Myrtle Beach to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Indianapolis in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Indianapolis

How much does it cost to fly round-trip from Myrtle Beach to Indianapolis?

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated May 5, 2026.
Read reviews from past customers who have flown American Airlines and Spirit Airlines from Myrtle Beach to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

6.9

Overall

7.1

Crew

7.9

Boarding

7.5

Food

6.4

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Entertainment

6.9

Overall

7.1

Crew

7.9

Boarding

7.5

Food

6.4

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Entertainment

6.9

Overall

7.1

Crew

7.9

Boarding

7.5

Food

6.4

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Myrtle Beach to Indianapolis?

    There are many flights that can get you from Myrtle Beach to Indianapolis in 6h 46m. Fly via Southwest or Delta to get the fastest option. The distance from Myrtle Beach to Indianapolis is about 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Myrtle Beach to Indianapolis round-trip?

    Our cheapest airline available from Myrtle Beach to Indianapolis is Spirit Airlines. Our recent data shows that you can find tickets from as low as $83 on this airline. An additional option worth looking into is American Airlines, starting at $271. Spirit Airlines is currently priced 75% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Myrtle Beach to Indianapolis one-way?

    For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $38. Users have also found prices from $77 and $127 on Spirit Airlines and Delta, respectively.

  • Can I find deals for flights from Myrtle Beach to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Indianapolis.

  • Can I find deals for business class flights from Myrtle Beach to Indianapolis?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Greenwood
Fishers
Kokomo
Plainfield
Mooresville
Anderson
Franklin
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Noblesville
Bloomington

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Alternative routes for Myrtle Beach to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Myrtle Beach to Indianapolis

Discover the top 2 airlines that operate flights from Myrtle Beach to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$83Average$173FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$271Average$399FlexibilityNo cancel feeOn-time71%

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