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$93+ Cheap flights from Myrtle Beach to Indianapolis (MYR - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — IND
May 10 — May 171
Sun 5/10
Sun 5/17
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Indianapolis

Cheapest flights from Myrtle Beach to Indianapolis
Explore the most affordable flight options available from Myrtle Beach to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
MYR
-
IND
1 stop5h 21m
Spirit Airlines
Sat 5/912:26 pm
IND
-
MYR
1 stop8h 10m
Spirit Airlines
Deal found 4/9$186
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:52 am
MYR
-
IND
1 stop23h 57m
Multiple Airlines
Sun 5/35:30 am
IND
-
MYR
1 stop17h 59m
Multiple Airlines
Deal found 4/9$196
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2511:52 am
MYR
-
IND
1 stop12h 07m
Spirit Airlines
Sun 4/266:00 am
IND
-
MYR
1 stop13h 04m
Spirit Airlines
Deal found 4/8$205
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:52 am
MYR
-
IND
1 stop12h 07m
Spirit Airlines
Sun 5/35:30 am
IND
-
MYR
1 stop17h 59m
Spirit Airlines
Deal found 4/8$206
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:52 am
MYR
-
IND
1 stop12h 07m
Spirit Airlines
Sun 5/35:30 am
IND
-
MYR
1 stop17h 59m
Spirit Airlines
Deal found 4/9$208
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:52 am
MYR
-
IND
1 stop12h 07m
Spirit Airlines
Mon 4/276:00 am
IND
-
MYR
1 stop5h 01m
Spirit Airlines
Deal found 4/8$217
This CheapOair deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
MYR
-
IND
1 stop5h 21m
Spirit Airlines
Mon 5/188:36 pm
IND
-
MYR
1 stop12h 38m
Spirit Airlines
Deal found 4/5$221
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/233:32 pm
MYR
-
IND
2 stops32h 27m
Multiple Airlines
Mon 4/2711:29 am
IND
-
MYR
1 stop12h 00m
Multiple Airlines
Deal found 4/8$234

Find flight deals from Myrtle Beach to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$186
(Cheapflightsfares)

One-way from

$93
(Cheapflightsfares)

Popular in

March

Cheapest in

August

Average price

$335

Good one-way deal

$119 or less
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
Search Deals
From Myrtle Beach Intl to Indianapolis
Search Deals
One-way flight from Myrtle Beach Intl to Indianapolis
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($45 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a one-way flight from Myrtle Beach Intl to Indianapolis.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 4/29

11:52 am-11:59 pm

1 stop12h 07m

Indianapolis

Sun 5/3

5:30 am-11:29 pm

1 stop17h 59m

$220

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 5/15

6:00 am-11:21 am

1 stop5h 21m

Indianapolis

Mon 5/18

8:36 pm-9:14 am

1 stop12h 38m

$221

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 4/22

11:28 am-11:59 pm

1 stop12h 31m

Indianapolis

Sun 4/26

12:12 pm-11:29 pm

2 stops35h 17m

$241

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 4/29

4:05 pm-10:50 pm

2 stops6h 45m

Indianapolis

Sun 5/3

6:45 am-3:05 pm

2 stops8h 20m

$349

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 7/30

1:21 pm-10:12 am

2 stops20h 51m

Indianapolis

Sun 8/2

5:45 am-2:50 pm

1 stop9h 05m

$355

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 4/30

8:30 am-4:00 pm

2 stops7h 30m

Indianapolis

Sun 5/3

6:45 am-3:05 pm

2 stops8h 20m

$358

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 9/18

6:40 am-12:40 pm

1 stop6h 00m

Indianapolis

Sun 9/20

5:50 am-10:15 am

1 stop4h 25m

$387
Quickest round-trip

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 9/17

8:10 am-12:10 pm

1 stop4h 00m

Indianapolis

Mon 9/21

3:30 pm-7:40 pm

1 stop4h 10m

$387

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 5/14

1:45 pm-11:00 pm

1 stop9h 15m

Indianapolis

Sun 5/17

6:45 am-3:05 pm

2 stops8h 20m

$389

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 9/18

6:40 am-12:40 pm

1 stop6h 00m

Indianapolis

Mon 9/21

5:25 am-2:45 pm

2 stops9h 20m

$392

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/6

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Myrtle Beach to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Indianapolis in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Indianapolis

What is the cheapest month to book a flight from Myrtle Beach to Indianapolis?

Currently, October is the cheapest month in which you can book a flight from Myrtle Beach to Indianapolis (average of $40). Flying from Myrtle Beach to Indianapolis in January is currently the most expensive (average of $105). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Myrtle Beach to Indianapolis?

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated April 10, 2026.
Read reviews from past customers who have flown American Airlines and Spirit Airlines from Myrtle Beach to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,564 reviews

Entertainment

6.8

Overall

7.1

Comfort

7.2

Food

6.4

Crew

7.9

Boarding

7.5

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,564 reviews
American Airlines
7.1
Good
11,564 reviews

Entertainment

6.8

Overall

7.1

Comfort

7.2

Food

6.4

Crew

7.9

Boarding

7.5

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
Spirit Airlines
6.3
Okay
8,607 reviews
American Airlines
7.1
Good
11,564 reviews

Entertainment

6.8

Overall

7.1

Comfort

7.2

Food

6.4

Crew

7.9

Boarding

7.5

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Indianapolis?

    There are many flights that can get you from Myrtle Beach to Indianapolis in 6h 45m. Fly via Spirit Airlines or Southwest to get the fastest option. The distance from Myrtle Beach to Indianapolis is about 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Myrtle Beach to Indianapolis round-trip?

    Our cheapest airline available from Myrtle Beach to Indianapolis is Spirit Airlines. Our recent data shows that you can find tickets from as low as $83 on this airline. An additional option worth looking into is American Airlines, starting at $271. Spirit Airlines is currently priced 75% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Myrtle Beach to Indianapolis one-way?

    For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $38. Users have also found prices from $75 and $127 on Spirit Airlines and Delta, respectively.

  • What are the cheapest flights from Myrtle Beach to Indianapolis?

    Looking at all options, your cheapest flight can be booked for $94. While the most popular route (Myrtle Beach Intl - Indianapolis) can be booked for $186 on average, our data indicates $119 when flying from Myrtle Beach to Indianapolis.

  • Can I find deals for flights from Myrtle Beach to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Indianapolis.

  • Can I find deals for business class flights from Myrtle Beach to Indianapolis?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Indianapolis?

    Currently, October is the cheapest month in which you can book a flight from Myrtle Beach to Indianapolis (average of $40). Flying from Myrtle Beach to Indianapolis in January is currently the most expensive (average of $105). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Greenwood
Fishers
Kokomo
Plainfield
Mooresville
Anderson
Franklin
Carmel
Noblesville
Bloomington
Crawfordsville

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Myrtle Beach to Indianapolis

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Top 2 airlines flying from Myrtle Beach to Indianapolis

Discover the top 2 airlines that operate flights from Myrtle Beach to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$83Average$170FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$271Average$382FlexibilityNo cancel feeOn-time71%

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