$136+ Cheap flights from Myrtle Beach to Indianapolis (MYR - IND)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — IND
Oct 30 — Nov 61
Round-trip
1 adult, Economy
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Find cheap flights from Myrtle Beach to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Indianapolis
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Cheapest flights from Myrtle Beach to IndianapolisExplore the most affordable flight options available from Myrtle Beach to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
Explore the most affordable flight options available from Myrtle Beach to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:12 pm -
2 stops18h 50m
Tue 11/171:33 pm -
1 stop19h 40m
Deal found 9/26![Multiple Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:53 pm -
1 stop22h 50m
Mon 11/97:52 pm -
2 stops39h 52m
Deal found 9/27![Multiple Airlines logo]()
$253
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:22 am -
1 stop5h 54m
Tue 11/36:32 pm -
1 stop3h 57m
Deal found 9/30![American Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:50 am -
1 stop4h 05m
Tue 11/39:40 am -
2 stops8h 45m
Deal found 9/30![Southwest logo]()
$276
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:27 am -
2 stops10h 47m
Sat 10/316:00 am -
2 stops11h 11m
Deal found 9/29![United Airlines logo]()
$282
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2512:10 pm -
1 stop4h 21m
Tue 1/56:00 am -
1 stop4h 08m
Deal found 9/30![Delta logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:03 pm -
1 stop19h 50m
Mon 11/97:52 pm -
2 stops39h 52m
Deal found 9/27![Multiple Airlines logo]()
$286
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/253:25 pm -
2 stops7h 20m
Tue 1/52:10 pm -
1 stop4h 15m
Deal found 9/30![Southwest logo]()
$289
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:30 pm -
1 stop17h 55m
Mon 11/96:00 am -
1 stop4h 07m
Deal found 9/27![Delta logo]()
$299
Best flights from Myrtle Beach to IndianapolisDiscover carefully curated flight deals from Myrtle Beach to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
Discover carefully curated flight deals from Myrtle Beach to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:27 am -
1 stop6h 14m
Sat 11/149:10 am -
2 stops8h 01m
Deal found 9/29![United Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2512:10 pm -
1 stop4h 21m
Tue 1/56:00 am -
1 stop4h 08m
Deal found 9/30![Delta logo]()
$284
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/253:25 pm -
2 stops7h 20m
Tue 1/56:45 am -
2 stops6h 30m
Deal found 9/28![Southwest logo]()
$328
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:55 pm -
2 stops8h 50m
Sat 10/316:40 am -
2 stops8h 35m
Deal found 9/26![Southwest logo]()
$328
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/267:03 pm -
1 stop5h 39m
Tue 1/56:25 pm -
1 stop4h 00m
Deal found 9/28![Delta logo]()
$334
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:55 pm -
1 stop4h 25m
Sun 11/85:30 am -
1 stop4h 35m
Deal found 9/27![Southwest logo]()
$334
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2512:10 pm -
1 stop6h 29m
Tue 12/297:05 am -
1 stop4h 20m
Deal found 9/26![Delta logo]()
$357
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:40 am -
1 stop5h 05m
Sun 11/16:50 am -
2 stops6h 10m
Deal found 9/27![Southwest logo]()
$339
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:55 pm -
2 stops8h 20m
Sun 10/256:10 pm -
1 stop4h 35m
Deal found 9/30![Southwest logo]()
$362
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/193:25 pm -
2 stops7h 25m
Fri 11/276:50 am -
2 stops6h 10m
Deal found 9/26![Southwest logo]()
$368
Last-minute flights from Myrtle Beach to IndianapolisDiscover last-minute flight deals from Myrtle Beach to Indianapolis. Data last updated September 30, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Indianapolis. Data last updated September 30, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:03 pm -
1 stop20h 12m
Sat 10/177:59 pm -
2 stops36h 04m
Deal found 9/28![Multiple Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:00 am -
1 stop5h 03m
Sun 10/256:04 am -
1 stop5h 39m
Deal found 9/30![American Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:55 pm -
2 stops8h 20m
Sun 10/256:10 pm -
1 stop4h 35m
Deal found 9/30![Southwest logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:22 am -
1 stop5h 54m
Tue 11/36:32 pm -
1 stop3h 57m
Deal found 9/30![American Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:50 am -
1 stop4h 05m
Tue 11/39:40 am -
2 stops8h 45m
Deal found 9/30![Southwest logo]()
$276
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:27 am -
2 stops10h 47m
Sat 10/316:00 am -
2 stops11h 11m
Deal found 9/29![United Airlines logo]()
$282
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:22 am -
1 stop3h 46m
Sun 11/13:28 pm -
1 stop6h 36m
Deal found 9/27![American Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:40 am -
1 stop5h 05m
Sun 11/16:50 am -
2 stops6h 10m
Deal found 9/27![Southwest logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:22 am -
1 stop5h 54m
Sat 10/316:00 am -
1 stop5h 13m
Deal found 9/26![American Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:55 pm -
2 stops8h 50m
Sat 10/315:20 am -
1 stop6h 50m
Deal found 9/26![Southwest logo]()
$289
One-way flights from Myrtle Beach to IndianapolisSearch for one-way flight options from Myrtle Beach to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
Search for one-way flight options from Myrtle Beach to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:30 am -
1 stop6h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![American Airlines logo]()
$136
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:55 pm -
2 stops8h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Southwest logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:58 pm -
3 stops45h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$170
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:35 am -
2 stops9h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Southwest logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:10 pm -
3 stops22h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:25 pm -
2 stops24h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$264
Find flight deals from Myrtle Beach to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (Kiwi.com) |
One-way from | $136 (American Airlines) |
Popular in | August |
Cheapest in | April |
Average price | $406 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Sat 11/7
5:55 pm-10:20 pm
1 stop4h 25m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Thu 10/22
6:30 am-1:08 pm
1 stop6h 38m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Thu 10/22
3:55 pm-12:15 am
2 stops8h 20m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$141
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Thu 10/22
8:10 pm-7:04 pm
3 stops22h 54m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$257
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Sun 10/11
6:25 pm-7:04 pm
2 stops24h 39m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$264
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Wed 11/11
11:27 am-5:41 pm
1 stop6h 14m
Indianapolis
Sat 11/14
9:10 am-5:11 pm
2 stops8h 01m
$276
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Fri 12/25
12:10 pm-4:31 pm
1 stop4h 21m
Indianapolis
Tue 1/5
6:00 am-10:08 am
1 stop4h 08m
$284
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Fri 12/25
3:25 pm-10:45 pm
2 stops7h 20m
Indianapolis
Tue 1/5
6:45 am-1:15 pm
2 stops6h 30m
$328
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Fri 10/30
3:55 pm-12:45 am
2 stops8h 50m
Indianapolis
Sat 10/31
6:40 am-3:15 pm
2 stops8h 35m
$328
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Sat 12/26
7:03 pm-12:42 am
1 stop5h 39m
Indianapolis
Tue 1/5
6:25 pm-10:25 pm
1 stop4h 00m
$334
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Indianapolis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Myrtle Beach with our price prediction graph.
MYR-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated September 30, 2026.
Read reviews from past customers who have flown American Airlines from Myrtle Beach to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.4
Overall
7.0
Food
6.4
Crew
7.9
Comfort
7.2
Entertainment
6.8
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Boarding
7.4
Overall
7.0
Food
6.4
Crew
7.9
Comfort
7.2
Entertainment
6.8
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Greenwood
Plainfield
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Crawfordsville
Anderson
Noblesville
Bloomington
Speedway
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Myrtle Beach and Indianapolis flights
Browse other Myrtle Beach and Indianapolis flight options. Last updated on September 30, 2026.
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Top airline flying from Myrtle Beach to Indianapolis
Discover the top airline that operate flights from Myrtle Beach to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$270 | Average$386 | FlexibilityNo cancel fee | On-time71% |