Indianapolis

$101+ Cheap flights from Myrtle Beach to Indianapolis (MYR - IND)

MYR — IND
Nov 29 — Dec 61
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1. Tell us where you want to go

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Cheap flight deals from Myrtle Beach to Indianapolis

Cheapest flights from Myrtle Beach to Indianapolis

Wed 11/258:10 pm -
1 stop21h 10m
Mon 11/3010:56 am -
1 stop22h 59m
Deal found 10/27$237
Thu 11/198:15 pm -
1 stop21h 05m
Tue 12/11:20 pm -
1 stop20h 08m
Deal found 10/25$251
Fri 11/136:12 pm -
2 stops17h 41m
Tue 11/171:33 pm -
1 stop19h 40m
Deal found 10/29$261
Thu 11/266:00 am -
1 stop4h 33m
Thu 12/36:43 am -
1 stop3h 58m
Deal found 10/29$279
Sun 11/222:46 pm -
1 stop19h 15m
Mon 11/3010:56 am -
1 stop22h 59m
Deal found 10/28$295
Tue 12/15:10 am -
1 stop4h 17m
Tue 12/15:24 pm -
1 stop4h 39m
Deal found 10/28$296
Sun 11/158:15 pm -
1 stop15h 38m
Wed 11/1812:38 pm -
1 stop26h 30m
Deal found 10/26$299
Fri 11/206:12 pm -
2 stops24h 23m
Tue 12/11:20 pm -
1 stop20h 08m
Deal found 10/25$300
Fri 11/201:53 pm -
1 stop27h 27m
Mon 11/3010:56 am -
1 stop22h 59m
Deal found 10/28$308
Thu 11/262:46 pm -
1 stop19h 15m
Thu 12/37:52 pm -
2 stops15h 52m
Deal found 10/29$310

Find flight deals from Myrtle Beach to Indianapolis

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$201
(Kiwi.com)

One-way from

$101
(Kiwi.com)

Popular in

August

Cheapest in

October

Average price

$270
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
From Myrtle Beach Intl to Indianapolis
One-way flight from Myrtle Beach Intl to Indianapolis
Highest demand for flights based on searches. 11% potential increase in price ($48 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Average for round-trip flights in October 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Myrtle Beach to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Fri 11/6

6:12 pm-11:53 am

2 stops17h 41m

Indianapolis

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$130
Quickest round-trip

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Sat 11/21

6:51 pm-12:40 am

1 stop5h 49m

Indianapolis

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$140

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Thu 11/5

8:15 pm-11:53 am

1 stop15h 38m

Indianapolis

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$146

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Sun 11/8

8:15 pm-11:53 am

1 stop15h 38m

Indianapolis

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$170

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Mon 11/30

2:41 pm-10:08 am

1 stop19h 27m

Indianapolis

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$171

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Thu 11/26

6:00 am-10:33 am

1 stop4h 33m

Indianapolis

Thu 12/3

6:43 am-10:41 am

1 stop3h 58m

$279

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Tue 12/1

6:00 am-10:38 am

1 stop4h 38m

Indianapolis

Tue 12/1

4:22 pm-10:47 pm

1 stop6h 25m

$335

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Thu 11/26

5:50 am-12:45 pm

1 stop6h 55m

Indianapolis

Mon 11/30

5:35 pm-9:55 pm

1 stop4h 20m

$338

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Thu 11/19

6:51 pm-12:40 am

1 stop5h 49m

Indianapolis

Sat 11/28

6:34 am-10:40 am

1 stop4h 06m

$338

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Wed 1/6

8:00 am-4:45 pm

2 stops8h 45m

Indianapolis

Tue 1/12

7:05 am-5:25 pm

2 stops10h 20m

$345

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 14 resultsSorted by cheapest first
1
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Compare providers for flights from Myrtle Beach to Indianapolis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Indianapolis in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Myrtle Beach with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Indianapolis

How much does it cost to fly round-trip from Myrtle Beach to Indianapolis?

Airfare is typical for this route at the moment.

Myrtle Beach to Indianapolis flights typically cost between $176 and $528 in January.
The cheapest round-trip price found within the last 5 days was $201 on Multiple Airlines (Jan 7-Jan 13).

Reviews of airlines servicing Indianapolis

Read reviews from past customers who have flown American Airlines from Myrtle Beach to Indianapolis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

6.8

Food

6.4

Comfort

7.1

Overall

7.0

Boarding

7.4

Crew

7.9

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Entertainment

6.8

Food

6.4

Comfort

7.1

Overall

7.0

Boarding

7.4

Crew

7.9

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Related info for your journey

  • How long is the flight from Myrtle Beach to Indianapolis?

    There are many flights that can get you from Myrtle Beach to Indianapolis in 4h 33m. Fly via Delta or Southwest to get the fastest option. The distance from Myrtle Beach to Indianapolis is about 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Myrtle Beach to Indianapolis round-trip?

    Our cheapest airline available from Myrtle Beach to Indianapolis is American Airlines. Our recent data shows that you can find tickets from as low as $270 on this airline. American Airlines is currently priced 30% below the average price you’ll pay for this route.

  • Can I find deals for flights from Myrtle Beach to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Indianapolis.

  • Can I find deals for business class flights from Myrtle Beach to Indianapolis?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Plainfield
Greenwood
Terre Haute
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Crawfordsville
Anderson
Carmel
Bloomington
Noblesville
Speedway

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Myrtle Beach to Indianapolis

Top airline flying from Myrtle Beach to Indianapolis

AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$270Average$382FlexibilityNo cancel feeOn-time71%

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