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$78+ Cheap flights from Missouri to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — IND
Jan 20 — Jan 271
Tue 1/20
Tue 1/27
1 adult, Economy
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Cheap flight deals from Missouri to Indianapolis

Cheapest flights from Missouri to Indianapolis
Explore the most affordable flight options available from Missouri to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 21, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:15 pmMCI - IND
1 stop24h 49mMultiple Airlines
Sat 1/248:26 pmIND - MCI
1 stop15h 05mMultiple Airlines
Deal found 12/18$359
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:59 pmMCI - IND
1 stop4h 24mDelta
Thu 1/16:35 amIND - MCI
1 stop4h 09mDelta
Deal found 12/21$387
This Delta deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:42 amMCI - IND
1 stop4h 23mDelta
Sun 12/286:30 amIND - MCI
1 stop4h 26mDelta
Deal found 12/19$407
This Kiwi.com deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:15 pmMCI - IND
2 stops20h 41mMultiple Airlines
Thu 1/111:32 amIND - MCI
1 stop30h 38mMultiple Airlines
Deal found 12/19$448
This Kiwi.com deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:48 amSTL - IND
1 stop5h 56mFrontier
Sun 1/45:06 pmIND - STL
1 stop17h 39mFrontier
Deal found 12/20$449
This Kiwi.com deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:48 amSTL - IND
1 stop5h 56mMultiple Airlines
Sun 1/45:06 pmIND - STL
2 stops42h 50mMultiple Airlines
Deal found 12/20$453
This American Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:19 pmMCI - IND
1 stop4h 33mAmerican Airlines
Sat 1/39:36 amIND - MCI
1 stop6h 16mAmerican Airlines
Deal found 12/19$470
This Delta deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:02 pmSTL - IND
1 stop4h 10mDelta
Fri 1/234:24 pmIND - STL
1 stop5h 13mDelta
Deal found 12/19$501
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amMCI - IND
1 stop7h 26mAmerican Airlines
Sun 12/287:00 amIND - MCI
1 stop5h 24mAmerican Airlines
Deal found 12/21$519
This United Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:35 pmMCI - IND
1 stop4h 09mUnited Airlines
Thu 1/12:35 pmIND - MCI
2 stops8h 15mUnited Airlines
Deal found 12/19$530
This Southwest deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:15 pmMCI - IND
Nonstop1h 25mSouthwest
Sat 1/247:20 amIND - MCI
1 stop6h 10mSouthwest
Deal found 12/18$537
This Kiwi.com deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:27 pmSTL - IND
1 stop29h 16mMultiple Airlines
Fri 1/238:26 pmIND - STL
2 stops15h 45mMultiple Airlines
Deal found 12/19$545

Find flight deals from Missouri to Indianapolis

Keep the following information in mind while searching for Missouri to Indianapolis flight deals. Data was last updated December 21, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$153
(Kiwi.com)

One-way from

$78
(Kiwi.com)

Popular in

November

Cheapest in

April

Average price

$276

Good round-trip deal

$451 or less

Good one-way deal

$224 or less
Provider with most accurate pricing for Lambert-St Louis-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Indianapolis flights.
Search Deals
From Missouri to Indianapolis
Search Deals
One-way flight from Missouri to Indianapolis
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($49 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Missouri to Indianapolis.
Search Deals
Price to beat on a one-way flight from Missouri to Indianapolis.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from Missouri to Indianapolis that are best for you.

Fly from

Missouri

Fly to

Indianapolis

Route

Depart

Return

Price

St. LouisIndianapolis

STL - IND

STLIND

Lambert-St Louis

Mon 2/2

5:42 pm-9:43 am

1 stop15h 01m

Indianapolis

Mon 2/9

7:33 pm-10:27 pm

1 stop27h 54m

$153

St. LouisIndianapolis

STL - IND

STLIND

Lambert-St Louis

Tue 1/20

5:42 pm-6:23 pm

1 stop23h 41m

Indianapolis

Thu 1/22

2:12 pm-11:33 pm

1 stop10h 21m

$154

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Thu 2/5

11:26 am-10:48 pm

1 stop10h 22m

Indianapolis

Sun 2/8

8:26 pm-10:31 am

1 stop15h 05m

$208

St. LouisIndianapolis

STL - IND

STLIND

Lambert-St Louis

Sat 1/17

5:11 pm-9:43 am

1 stop15h 32m

Indianapolis

Sat 1/24

8:26 pm-9:21 am

2 stops37h 55m

$224

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Fri 2/6

8:00 am-1:18 pm

1 stop4h 18m

Indianapolis

Mon 2/9

6:00 pm-9:59 pm

1 stop4h 59m

$237

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Fri 1/23

5:49 pm-11:06 pm

1 stop4h 17m

Indianapolis

Sun 1/25

3:43 pm-9:03 pm

1 stop6h 20m

$237

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Tue 3/17

6:35 am-11:11 am

1 stop3h 36m

Indianapolis

Tue 3/31

7:51 pm-11:03 pm

1 stop4h 12m

$237

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Fri 2/13

5:47 pm-12:07 am

1 stop5h 20m

Indianapolis

Sun 2/15

6:15 am-11:33 am

1 stop6h 18m

$237

St. LouisIndianapolis

STL - IND

STLIND

Lambert-St Louis

Sat 1/17

11:05 am-6:14 pm

1 stop6h 09m

Indianapolis

Sat 1/24

12:32 pm-6:13 pm

1 stop6h 41m

$240

St. LouisIndianapolis

STL - IND

STLIND

Lambert-St Louis

Sat 1/17

6:30 am-1:18 pm

1 stop5h 48m

Indianapolis

Sat 1/24

6:00 pm-9:13 pm

1 stop4h 13m

$240

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/20

Showing 1-10 of 32 results
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Best time to book a flight from Missouri to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Indianapolis

What is the cheapest month to book a flight from Missouri to Indianapolis?

Currently, November is the cheapest month in which you can book a flight from Missouri to Indianapolis (average of $146). Flying from Missouri to Indianapolis in June is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IND?

Find hourly flight availability from Missouri to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 21, 2025.

One of the essential ways to save on airfare from Missouri to Indianapolis is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 55% on airfare.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Missouri?

    Indianapolis (IND) is the airport you will fly into if you book a flight from Missouri to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How popular is this Missouri to Indianapolis flight route?

    This flight path from Missouri to Indianapolis was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Indianapolis?

    Spirit Airlines, Delta, and American Airlines can get you from Missouri to Indianapolis in just under 4h 17m. Your travel time can differ by up to 6h 05m. The distance between Missouri and Indianapolis is about 449 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Missouri to Indianapolis?

    When deciding which route to take from Missouri to Indianapolis consider Kansas City - Indianapolis, Lambert-St Louis - Indianapolis or Springfield-Branson - Indianapolis as they are the most popular.

  • What are the cheapest flights from Missouri to Indianapolis?

    On average you can expect to pay $393 for a flight from Missouri to Indianapolis. The cheapest flight overall is $224 while the most popular route, (Kansas City - Indianapolis) is currently priced at $208.

  • Can I find deals for flights from Missouri to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Missouri to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Indianapolis.

  • Can I find deals for business class flights from Missouri to Indianapolis?

    Yes. Cheapflights offers flight deals from Missouri to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Indianapolis?

    Currently, November is the cheapest month in which you can book a flight from Missouri to Indianapolis (average of $146). Flying from Missouri to Indianapolis in June is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Noblesville
Fishers
Greenwood
Plainfield
Anderson
Kokomo
Franklin
Carmel
Crawfordsville
Bloomington
Speedway

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Indianapolis

Discover the top 4 airlines that operate flights from Missouri to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$178Average$321FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$198Average$402FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$204Average$345FlexibilityNo cancel feeOn-time63%
DeltaCheapest$204Average$236FlexibilityNo cancel feeOn-timeN/A

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