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Indianapolis

$69+ Cheap flights from Missouri to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
STL — IND
Apr 21 — Apr 281
Tue 4/21
Tue 4/28
1 adult, Economy
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Cheap flight deals from Missouri to Indianapolis

Cheapest flights from Missouri to Indianapolis
Explore the most affordable flight options available from Missouri to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.

This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:34 pm
MCI
-
IND
1 stop28h 20m
Frontier
Tue 5/198:39 pm
IND
-
MCI
1 stop18h 10m
Frontier
Deal found 3/18$191
This Frontier deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/199:55 pm
STL
-
IND
1 stop14h 02m
Frontier
Sun 4/261:20 pm
IND
-
STL
1 stop10h 59m
Frontier
Deal found 3/21$205
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/278:40 pm
MCI
-
IND
1 stop21h 58m
Frontier
Sun 3/298:33 pm
IND
-
MCI
1 stop24h 20m
Frontier
Deal found 3/20$241
This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:34 pm
MCI
-
IND
1 stop28h 20m
Frontier
Mon 6/112:14 pm
IND
-
MCI
1 stop6h 15m
Frontier
Deal found 3/18$257
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:06 pm
STL
-
IND
1 stop22h 54m
Frontier
Thu 4/236:08 pm
IND
-
STL
2 stops13h 42m
Frontier
Deal found 3/18$258
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:39 am
STL
-
IND
1 stop5h 43m
Frontier
Fri 4/243:00 pm
IND
-
STL
1 stop9h 19m
Frontier
Deal found 3/20$260
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:10 pm
MCI
-
IND
Nonstop1h 25m
Southwest
Tue 5/1911:05 am
IND
-
MCI
Nonstop1h 35m
Southwest
Deal found 3/18$267
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
MCI
-
IND
1 stop4h 42m
Delta
Wed 4/225:29 pm
IND
-
MCI
1 stop6h 32m
Delta
Deal found 3/19$277
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:30 pm
MCI
-
IND
Nonstop1h 25m
Southwest
Mon 6/11:05 pm
IND
-
MCI
Nonstop1h 30m
Southwest
Deal found 3/18$279
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:54 am
STL
-
IND
1 stop6h 59m
American Airlines
Thu 4/168:16 am
IND
-
STL
1 stop6h 06m
American Airlines
Deal found 3/20$281
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:10 pm
MCI
-
IND
Nonstop1h 25m
Southwest
Thu 4/1610:30 am
IND
-
MCI
1 stop7h 35m
Southwest
Deal found 3/19$283
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:17 pm
STL
-
IND
2 stops13h 54m
Frontier
Thu 4/3012:17 pm
IND
-
STL
1 stop19h 33m
Frontier
Deal found 3/18$283

Find flight deals from Missouri to Indianapolis

Keep the following information in mind while searching for Missouri to Indianapolis flight deals. Data was last updated March 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$191
(CheapOair)

One-way from

$69
(Kiwi.com)

Popular in

January

Cheapest in

August

Average price

$572

Good round-trip deal

$329 or less
Provider with most accurate pricing for Lambert-St Louis-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Indianapolis flights.
Search Deals
From Missouri to Indianapolis
Search Deals
One-way flight from Missouri to Indianapolis
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($89 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Missouri to Indianapolis.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Missouri to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisIndianapolis

STL - IND

STLIND

Lambert-St Louis

Thu 4/16

8:06 pm-8:00 pm

1 stop22h 54m

Indianapolis

Thu 4/23

6:08 pm-6:50 am

2 stops13h 42m

$258

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Wed 4/15

6:00 am-11:42 am

1 stop4h 42m

Indianapolis

Wed 4/22

5:29 pm-11:01 pm

1 stop6h 32m

$277

St. LouisIndianapolis

STL - IND

STLIND

Lambert-St Louis

Tue 6/9

6:00 am-3:28 pm

1 stop8h 28m

Indianapolis

Thu 6/11

8:49 pm-11:54 pm

1 stop4h 05m

$300

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Fri 4/3

8:43 pm-7:32 pm

1 stop21h 49m

Indianapolis

Sun 4/5

8:27 pm-7:58 pm

1 stop24h 31m

$306

St. LouisIndianapolis

STL - IND

STLIND

Lambert-St Louis

Wed 5/13

6:04 pm-11:59 pm

1 stop4h 55m

Indianapolis

Fri 5/15

6:30 am-9:29 am

1 stop3h 59m

$306
Quickest round-trip

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Tue 6/9

2:00 pm-4:25 pm

Nonstop1h 25m

Indianapolis

Thu 6/11

1:45 pm-2:15 pm

Nonstop1h 30m

$308

SpringfieldIndianapolis

SGF - IND

SGFIND

Springfield-Branson

Fri 4/17

6:50 pm-11:39 pm

1 stop3h 49m

Indianapolis

Sun 4/19

9:20 pm-12:36 am

1 stop4h 16m

$309

SpringfieldIndianapolis

SGF - IND

SGFIND

Springfield-Branson

Fri 4/17

5:19 am-1:10 pm

1 stop6h 51m

Indianapolis

Sun 4/19

5:55 am-9:51 am

1 stop4h 56m

$309

SpringfieldIndianapolis

SGF - IND

SGFIND

Springfield-Branson

Thu 6/18

6:45 pm-12:34 am

1 stop4h 49m

Indianapolis

Thu 6/25

6:25 pm-10:35 pm

1 stop5h 10m

$309

SpringfieldIndianapolis

SGF - IND

SGFIND

Springfield-Branson

Sat 5/9

5:19 am-10:19 am

1 stop4h 00m

Indianapolis

Mon 5/18

5:33 pm-9:05 pm

1 stop4h 32m

$310

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/17

Showing 1-10 of 53 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Indianapolis

What is the cheapest month to book a flight from Missouri to Indianapolis?

Currently, November is the cheapest month in which you can book a flight from Missouri to Indianapolis (average of $146). Flying from Missouri to Indianapolis in January is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IND?

Find hourly flight availability from Missouri to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 22, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Indianapolis as you normally would.

How much does it cost to fly round-trip from Missouri to Indianapolis?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Missouri?

    Indianapolis (IND) is the airport you will fly into if you book a flight from Missouri to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How long is the flight from Missouri to Indianapolis?

    Frontier, Delta, and American Airlines can get you from Missouri to Indianapolis in just under 4h 42m. Your travel time can differ by up to 18h 12m. The distance between Missouri and Indianapolis is about 449 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Indianapolis one-way?

    For one-way options, check prices for Southwest. According to our data, you can fly for as low as $78. Users have also found prices from $87 and $110 on American Airlines and Delta, respectively.

  • What are the most popular routes from Missouri to Indianapolis?

    When deciding which route to take from Missouri to Indianapolis consider Kansas City - Indianapolis, Lambert-St Louis - Indianapolis or Springfield-Branson - Indianapolis as they are the most popular.

  • Can I find deals for flights from Missouri to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Missouri to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Indianapolis.

  • Can I find deals for business class flights from Missouri to Indianapolis?

    Yes. Cheapflights offers flight deals from Missouri to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Indianapolis?

    Currently, November is the cheapest month in which you can book a flight from Missouri to Indianapolis (average of $146). Flying from Missouri to Indianapolis in January is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Fishers
Noblesville
Greenwood
Plainfield
Mooresville
Anderson
Franklin
Carmel
Kokomo
Crawfordsville
Bloomington

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Indianapolis

Discover the top 4 airlines that operate flights from Missouri to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$176Average$323FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$204Average$332FlexibilityNo cancel feeOn-time63%
DeltaCheapest$204Average$276FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$204Average$362FlexibilityNo cancel feeOn-time69%

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