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$61+ Cheap flights from Missouri to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
STL — IND
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Missouri to Indianapolis

Keep the following information in mind while searching for Missouri to Indianapolis flight deals. Data was last updated September 16, 2025.

Round-trip from

$159
(American Airlines)

One-way from

$61
(United Airlines)

Popular in

March

Cheapest in

October

Average price

$373

Good round-trip deal

$219 or less
From Missouri to Indianapolis
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One-way flight from Missouri to Indianapolis
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Highest demand for flights based on searches. 12% potential increase in price ($51 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Missouri to Indianapolis.
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Find flight deals from Missouri to Indianapolis

Cheapest flights from Missouri to Indianapolis
Explore the most affordable flight options available from Missouri to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/53:04 pmMCI - IND
1 stop6h 02mAmerican Airlines
Sat 12/65:24 pmIND - MCI
1 stop6h 30mAmerican Airlines
Deal found 9/14$159
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/217:40 amMCI - IND
1 stop4h 29mUnited Airlines
Sat 1/36:00 amIND - MCI
1 stop4h 18mUnited Airlines
Deal found 9/13$175
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/110:54 amMCI - IND
1 stop5h 06mAmerican Airlines
Sun 11/28:06 pmIND - MCI
1 stop4h 56mAmerican Airlines
Deal found 9/15$229
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:56 pmSGF - IND
1 stop4h 26mDelta
Tue 10/2110:00 amIND - SGF
1 stop5h 50mDelta
Deal found 9/14$229
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/67:30 pmSGF - IND
1 stop3h 39mAmerican Airlines
Tue 10/145:46 amIND - SGF
1 stop4h 52mAmerican Airlines
Deal found 9/15$230
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:15 amMCI - IND
1 stop6h 38mAmerican Airlines
Tue 10/146:30 pmIND - MCI
1 stop5h 43mAmerican Airlines
Deal found 9/14$234
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/11:30 pmMCI - IND
1 stop4h 13mAmerican Airlines
Mon 11/36:25 pmIND - MCI
1 stop3h 58mAmerican Airlines
Deal found 9/14$235
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:27 pmMCI - IND
1 stop4h 11mUnited Airlines
Mon 12/85:49 pmIND - MCI
1 stop5h 09mUnited Airlines
Deal found 9/16$237
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:00 amMCI - IND
1 stop4h 13mUnited Airlines
Sun 11/236:00 amIND - MCI
1 stop3h 56mUnited Airlines
Deal found 9/15$238
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/298:40 pmSTL - IND
2 stops23h 25mMultiple Airlines
Sat 11/110:15 amIND - STL
1 stop8h 55mMultiple Airlines
Deal found 9/15$239
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/18:40 pmSTL - IND
2 stops12h 04mFrontier
Mon 11/33:39 pmIND - STL
2 stops18h 28mFrontier
Deal found 9/16$245
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/110:30 amMCI - IND
Nonstop1h 25mSouthwest
Mon 11/31:25 pmIND - MCI
Nonstop1h 35mSouthwest
Deal found 9/15$247

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Missouri to Indianapolis that are best for you.

Fly from

Missouri

Fly to

Indianapolis

Route

Depart

Return

Price

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Fri 12/5

3:04 pm-10:06 pm

1 stop6h 02m

Indianapolis

Sat 12/6

5:24 pm-10:54 pm

1 stop6h 30m

$159

SpringfieldIndianapolis

SGF - IND

SGFIND

Springfield-Branson

Tue 10/14

6:56 pm-12:22 am

1 stop4h 26m

Indianapolis

Tue 10/21

10:00 am-2:50 pm

1 stop5h 50m

$229

SpringfieldIndianapolis

SGF - IND

SGFIND

Springfield-Branson

Mon 10/6

7:30 pm-12:09 am

1 stop3h 39m

Indianapolis

Tue 10/14

5:46 am-9:38 am

1 stop4h 52m

$230

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Tue 10/14

5:38 pm-11:44 pm

1 stop5h 06m

Indianapolis

Thu 10/16

6:56 pm-12:09 am

1 stop6h 13m

$234

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Sat 11/1

1:30 pm-6:43 pm

1 stop4h 13m

Indianapolis

Mon 11/3

6:25 pm-9:23 pm

1 stop3h 58m

$235

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Fri 12/5

6:27 pm-11:38 pm

1 stop4h 11m

Indianapolis

Mon 12/8

5:49 pm-9:58 pm

1 stop5h 09m

$237

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Fri 11/21

6:00 am-11:13 am

1 stop4h 13m

Indianapolis

Sun 11/23

6:00 am-8:56 am

1 stop3h 56m

$238

St. LouisIndianapolis

STL - IND

STLIND

Lambert-St Louis

Wed 10/29

8:40 pm-9:05 pm

2 stops23h 25m

Indianapolis

Sat 11/1

10:15 am-6:10 pm

1 stop8h 55m

$239

St. LouisIndianapolis

STL - IND

STLIND

Lambert-St Louis

Sat 11/1

8:40 pm-9:44 am

2 stops12h 04m

Indianapolis

Mon 11/3

3:39 pm-9:07 am

2 stops18h 28m

$245

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Sat 11/1

10:30 am-12:55 pm

Nonstop1h 25m

Indianapolis

Mon 11/3

1:25 pm-2:00 pm

Nonstop1h 35m

$247

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 48 results
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Best time to book a flight from Missouri to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Indianapolis

What is the cheapest month to book a flight from Missouri to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Missouri to Indianapolis (average of $286). Flying from Missouri to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IND?

Find hourly flight availability from Missouri to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Indianapolis as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Missouri?

    Indianapolis (IND) is the airport you will fly into if you book a flight from Missouri to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How long is the flight from Missouri to Indianapolis?

    American Airlines, Delta, and Frontier can get you from Missouri to Indianapolis in just under 4h 26m. Your travel time can differ by up to 7h 38m. The distance between Missouri and Indianapolis is about 419 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Indianapolis one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $61. Users have also found prices from $72 and $129 on Frontier and Delta, respectively.

  • What are the most popular routes from Missouri to Indianapolis?

    When deciding which route to take from Missouri to Indianapolis consider Kansas City - Indianapolis, Lambert-St Louis - Indianapolis or Springfield-Branson - Indianapolis as they are the most popular.

  • Can I find deals for flights from Missouri to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Missouri to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Indianapolis.

  • Can I find deals for business class flights from Missouri to Indianapolis?

    Yes. Cheapflights offers flight deals from Missouri to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Indianapolis (average of $286). Flying from Missouri to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Noblesville
Fishers
Anderson
Kokomo
Greenwood
Bloomington
Franklin
Plainfield
Carmel
Crawfordsville
Speedway

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Alternative routes for Missouri to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Indianapolis

Discover the top 4 airlines that operate flights from Missouri to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$180Average$315FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$204Average$351FlexibilityNo cancel feeOn-time63%
DeltaCheapest$204Average$297FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$226Average$452FlexibilityNo cancel feeOn-time69%

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