How long is the flight from Missouri to Indianapolis?

Delta, United Airlines, and American Airlines can get you from Missouri to Indianapolis in just under 4h 24m. Your travel time can differ by up to 1h 15m. The distance between Missouri and Indianapolis is about 449 mi. This flight may include one or multiple stops.

What are the cheapest airlines to fly from Missouri to Indianapolis one-way?

For one-way options, check prices for Delta. According to our data, you can fly for as low as $109. Users have also found prices from $112 and $119 on Spirit Airlines and United Airlines, respectively.

In terms of precipitation, rainfall in Indianapolis ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indianapolis when rainfall is around 2.3 in.

If weather is an important factor for your trip to Indianapolis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

What are the most popular routes from Missouri to Indianapolis?

When deciding which route to take from Missouri to Indianapolis consider Kansas City - Indianapolis, Lambert-St Louis - Indianapolis or Springfield-Branson - Indianapolis as they are the most popular.

What are the most popular airlines that fly from Missouri to Indianapolis?

The most popular airlines flying from Missouri to Indianapolis are Southwest, American Airlines and United Airlines. Something to consider prior to booking your flight.

What airport do you fly into for flights to Indianapolis from Missouri?

Indianapolis (IND) is the airport you will fly into if you book a flight from Missouri to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

Can I find deals for flights from Missouri to Indianapolis that include hotel bookings?

Yes. In addition to deals on Missouri to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Indianapolis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Indianapolis.

Can I find deals for business class flights from Missouri to Indianapolis?

Yes. Cheapflights offers flight deals from Missouri to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$55+ Cheap Flights from Missouri to Indianapolis

Q: How much does it cost to fly round-trip from Missouri to Indianapolis?

Airfare is below average for this route at the moment. Missouri to Indianapolis flights typically cost between $378 and $557 in November. The cheapest round-trip price found within the last 3 days was $222 on Multiple Airlines (Nov 14-Nov 18).

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Cheap flight deals from Missouri to Indianapolis

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$159 (Mytrip)
One-way from	$55 (Priceline)
Popular in	March
Cheapest in	April
Average price	$430

Provider with most accurate pricing for Lambert-St Louis-Indianapolis flight deals.

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Provider most trusted by Cheapflights users for Lambert-St Louis-Indianapolis flights.

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From Missouri to Indianapolis

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One-way flight from Missouri to Indianapolis

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Highest demand for flights based on searches. 3% potential increase in price ($12 potential increase over avg. RT price).

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Cheapest flight prices on average. 7% potential price decrease ($25 potential savings vs. average RT price).

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Average for round-trip flights in October 2025

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Find flight deals from Missouri to Indianapolis

Cheapest flights from Missouri to Indianapolis
Explore the most affordable flight options available from Missouri to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Mon 12/812:46 pmMCI - IND

1 stop5h 04mFrontier

Thu 12/117:19 pmIND - MCI

1 stop19h 34mFrontier

Deal found 10/28

$159

Wed 11/126:49 pmMCI - IND

1 stop23h 42mFrontier

Sun 11/168:39 pmIND - MCI

1 stop23h 54mFrontier

Deal found 10/29

$198

Thu 11/276:00 amMCI - IND

1 stop25h 47mMultiple Airlines

Thu 12/47:19 pmIND - MCI

1 stop19h 34mMultiple Airlines

Deal found 10/28

$199

Mon 12/812:46 pmMCI - IND

2 stops17h 57mMultiple Airlines

Thu 12/117:19 pmIND - MCI

1 stop19h 34mMultiple Airlines

Deal found 10/28

$207

Fri 11/145:05 pmSTL - IND

1 stop15h 38mMultiple Airlines

Tue 11/185:05 amIND - STL

2 stops30h 00mMultiple Airlines

Deal found 10/30

$222

Tue 11/256:00 amMCI - IND

1 stop25h 37mMultiple Airlines

Wed 11/269:29 pmIND - MCI

1 stop15h 34mMultiple Airlines

Deal found 10/29

$224

Fri 11/148:28 pmMCI - IND

1 stop20h 07mFrontier

Sun 11/168:39 pmIND - MCI

1 stop23h 54mFrontier

Deal found 10/28

$231

Tue 11/256:00 amMCI - IND

1 stop25h 37mMultiple Airlines

Tue 12/29:03 amIND - MCI

1 stop28h 00mMultiple Airlines

Deal found 10/28

$234

Mon 12/155:45 pmMCI - IND

1 stop5h 27mDelta

Wed 12/176:45 amIND - MCI

1 stop4h 15mDelta

Deal found 10/28

$237

Fri 10/318:28 pmMCI - IND

1 stop20h 07mFrontier

Sun 11/28:39 pmIND - MCI

1 stop23h 59mFrontier

Deal found 10/28

$240

Mon 11/176:58 pmSGF - IND

1 stop4h 28mDelta

Mon 11/246:00 amIND - SGF

1 stop5h 53mDelta

Deal found 10/30

$244

Tue 11/116:00 amMCI - IND

2 stops40h 20mSpirit Airlines

Tue 11/188:59 pmIND - MCI

1 stop16h 29mSpirit Airlines

Deal found 10/28

$248

Best flights from Missouri to Indianapolis
Discover carefully curated flight deals from Missouri to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2025.

Fri 11/145:05 pmSTL - IND

1 stop15h 38mMultiple Airlines

Tue 11/185:05 amIND - STL

2 stops30h 00mMultiple Airlines

Deal found 10/30

$222

Tue 12/305:59 pmMCI - IND

1 stop4h 24mDelta

Thu 1/16:35 amIND - MCI

1 stop4h 09mDelta

Deal found 10/28

$237

Mon 12/86:00 amMCI - IND

1 stop5h 52mAmerican Airlines

Wed 12/102:56 pmIND - MCI

1 stop5h 17mAmerican Airlines

Deal found 10/28

$237

Thu 11/133:20 pmSGF - IND

1 stop5h 39mUnited Airlines

Mon 11/1712:38 pmIND - SGF

1 stop6h 08mUnited Airlines

Deal found 10/29

$259

Tue 11/256:30 pmSTL - IND

1 stop4h 50mSouthwest

Tue 12/27:50 amIND - STL

2 stops7h 50mSouthwest

Deal found 10/28

$322

Wed 11/267:03 pmSTL - IND

1 stop22h 23mFrontier

Sun 11/309:55 pmIND - STL

1 stop21h 23mFrontier

Deal found 10/28

$365

Tue 11/256:00 amMCI - IND

1 stop25h 37mMultiple Airlines

Wed 11/269:29 pmIND - MCI

1 stop15h 34mMultiple Airlines

Deal found 10/29

$224

Wed 12/106:29 amMCI - IND

1 stop5h 59mDelta

Fri 12/122:08 pmIND - MCI

1 stop3h 52mDelta

Deal found 10/28

$237

Wed 12/106:40 amMCI - IND

1 stop4h 27mDelta

Sun 12/144:46 pmIND - MCI

1 stop5h 27mDelta

Deal found 10/30

$237

Thu 11/137:02 pmSTL - IND

1 stop28h 49mMultiple Airlines

Mon 11/173:34 pmIND - STL

2 stops18h 33mMultiple Airlines

Deal found 10/29

$260

Tue 12/95:45 pmMCI - IND

1 stop5h 27mDelta

Thu 12/117:57 pmIND - MCI

1 stop4h 13mDelta

Deal found 10/28

$237

Tue 11/253:43 pmSTL - IND

1 stop5h 13mAmerican Airlines

Tue 12/28:42 amIND - STL

1 stop6h 01mAmerican Airlines

Deal found 10/28

$287

Mon 12/152:13 pmMCI - IND

1 stop3h 51mDelta

Sat 1/35:45 pmIND - MCI

1 stop4h 20mDelta

Deal found 10/28

$237

Mon 12/155:45 pmMCI - IND

1 stop5h 27mDelta

Wed 12/176:45 amIND - MCI

1 stop4h 15mDelta

Deal found 10/28

$237

Tue 11/253:57 pmSGF - IND

1 stop5h 04mAmerican Airlines

Sat 11/294:49 pmIND - SGF

1 stop5h 23mAmerican Airlines

Deal found 10/30

$318

Thu 11/1311:07 amSTL - IND

2 stops31h 57mMultiple Airlines

Sun 11/168:39 pmIND - STL

1 stop13h 28mMultiple Airlines

Deal found 10/28

$314

Wed 3/41:15 pmSGF - IND

1 stop7h 09mAmerican Airlines

Sat 3/75:44 amIND - SGF

1 stop6h 55mAmerican Airlines

Deal found 10/29

$324

Mon 11/176:58 pmSGF - IND

1 stop4h 28mDelta

Mon 11/246:00 amIND - SGF

1 stop5h 53mDelta

Deal found 10/30

$244

Tue 11/253:14 pmSTL - IND

2 stops28h 54mMultiple Airlines

Tue 12/29:03 amIND - STL

1 stop14h 30mMultiple Airlines

Deal found 10/28

$322

Thu 11/2010:53 amSTL - IND

1 stop7h 58mMultiple Airlines

Sun 11/309:55 pmIND - STL

1 stop21h 23mMultiple Airlines

Deal found 10/28

$335

Fri 12/267:03 amSGF - IND

1 stop5h 15mAmerican Airlines

Mon 12/297:25 pmIND - SGF

1 stop5h 31mAmerican Airlines

Deal found 10/30

$421

Fri 12/266:20 pmSGF - IND

1 stop4h 24mUnited Airlines

Mon 12/297:44 pmIND - SGF

2 stops19h 54mUnited Airlines

Deal found 10/30

$610

Fri 12/267:03 amSGF - IND

1 stop5h 15mAmerican Airlines

Sun 12/287:25 pmIND - SGF

1 stop5h 31mAmerican Airlines

Deal found 10/30

$421

Fri 12/266:20 pmSGF - IND

1 stop4h 24mUnited Airlines

Sun 12/287:44 pmIND - SGF

2 stops19h 54mUnited Airlines

Deal found 10/30

$646

Wed 3/46:00 amSGF - IND

2 stops14h 57mDelta

Sat 3/77:10 amIND - SGF

1 stop5h 54mDelta

Deal found 10/28

$453

Last-minute flights from Missouri to Indianapolis
Discover last-minute flight deals from Missouri to Indianapolis. Data last updated October 30, 2025 and is based on user searches.

Fri 10/318:28 pmMCI - IND

1 stop20h 07mFrontier

Sun 11/28:39 pmIND - MCI

1 stop23h 59mFrontier

Deal found 10/28

$240

Tue 11/116:00 amMCI - IND

2 stops40h 20mSpirit Airlines

Tue 11/188:59 pmIND - MCI

1 stop16h 29mSpirit Airlines

Deal found 10/28

$248

Wed 11/126:49 pmMCI - IND

1 stop23h 42mFrontier

Sun 11/168:39 pmIND - MCI

1 stop23h 54mFrontier

Deal found 10/29

$198

Wed 11/126:00 amMCI - IND

1 stop25h 44mMultiple Airlines

Sun 11/1610:21 pmIND - MCI

2 stops12h 56mMultiple Airlines

Deal found 10/29

$256

Thu 11/136:00 amMCI - IND

2 stops16h 20mSpirit Airlines

Fri 11/148:59 pmIND - MCI

1 stop16h 29mSpirit Airlines

Deal found 10/28

$252

Thu 11/133:20 pmSGF - IND

1 stop5h 39mUnited Airlines

Mon 11/1712:38 pmIND - SGF

1 stop6h 08mUnited Airlines

Deal found 10/29

$259

Fri 11/145:05 pmSTL - IND

1 stop15h 38mMultiple Airlines

Tue 11/185:05 amIND - STL

2 stops30h 00mMultiple Airlines

Deal found 10/30

$222

Fri 11/148:28 pmMCI - IND

1 stop20h 07mFrontier

Sun 11/168:39 pmIND - MCI

1 stop23h 54mFrontier

Deal found 10/28

$231

Mon 11/176:58 pmSGF - IND

1 stop4h 28mDelta

Mon 11/246:00 amIND - SGF

1 stop5h 53mDelta

Deal found 10/30

$244

Tue 11/256:00 amMCI - IND

1 stop25h 37mMultiple Airlines

Wed 11/269:29 pmIND - MCI

1 stop15h 34mMultiple Airlines

Deal found 10/29

$224

Tue 11/256:00 amMCI - IND

1 stop25h 37mMultiple Airlines

Tue 12/29:03 amIND - MCI

1 stop28h 00mMultiple Airlines

Deal found 10/28

$234

Thu 11/276:00 amMCI - IND

1 stop25h 47mMultiple Airlines

Thu 12/47:19 pmIND - MCI

1 stop19h 34mMultiple Airlines

Deal found 10/28

$199

One-way flights from Missouri to Indianapolis
Search for one-way flight options from Missouri to Indianapolis. Find affordable one-way fares based on user searches. Data last updated October 30, 2025.

Mon 12/1512:46 pmMCI - IND

1 stop5h 04mFrontier

Deal found 10/28

$55

Thu 12/48:09 pmMCI - IND

1 stop22h 44mFrontier

Deal found 10/30

$65

Mon 12/812:46 pmMCI - IND

1 stop5h 04mFrontier

Deal found 10/28

$75

Thu 12/118:09 pmMCI - IND

1 stop22h 44mFrontier

Deal found 10/30

$85

Thu 1/88:46 pmMCI - IND

1 stop22h 07mFrontier

Deal found 10/28

$89

Wed 1/281:44 pmMCI - IND

1 stop25h 27mMultiple Airlines

Deal found 10/30

$90

Fri 1/91:44 pmMCI - IND

1 stop25h 27mMultiple Airlines

Deal found 10/30

$91

Wed 1/211:44 pmMCI - IND

1 stop25h 27mMultiple Airlines

Deal found 10/30

$92

Fri 1/231:44 pmMCI - IND

1 stop25h 27mMultiple Airlines

Deal found 10/30

$93

Tue 1/131:44 pmMCI - IND

1 stop6h 16mSpirit Airlines

Deal found 10/30

$96

Thu 1/221:44 pmMCI - IND

1 stop6h 16mSpirit Airlines

Deal found 10/30

$97

Fri 11/78:28 pmMCI - IND

1 stop20h 07mFrontier

Deal found 10/28

$100

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisIndianapolis

STL - IND

STLIND

Lambert-St Louis

Fri 11/14

5:05 pm-9:43 am

1 stop15h 38m

Indianapolis

Tue 11/18

5:05 am-10:05 am

2 stops30h 00m

$222

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Tue 11/25

6:00 am-8:37 am

1 stop25h 37m

Indianapolis

Wed 11/26

9:29 pm-12:03 pm

1 stop15h 34m

$224

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Tue 12/30

5:59 pm-11:23 pm

1 stop4h 24m

Indianapolis

Thu 1/1

6:35 am-9:44 am

1 stop4h 09m

$237

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Mon 12/8

6:00 am-12:52 pm

1 stop5h 52m

Indianapolis

Wed 12/10

2:56 pm-7:13 pm

1 stop5h 17m

$237

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Wed 12/10

6:29 am-1:28 pm

1 stop5h 59m

Indianapolis

Fri 12/12

2:08 pm-5:00 pm

1 stop3h 52m

$237

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Wed 12/10

6:40 am-12:07 pm

1 stop4h 27m

Indianapolis

Sun 12/14

4:46 pm-9:13 pm

1 stop5h 27m

$237

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Tue 12/9

5:45 pm-12:12 am

1 stop5h 27m

Indianapolis

Thu 12/11

7:57 pm-11:10 pm

1 stop4h 13m

$237

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Mon 12/15

2:13 pm-7:04 pm

1 stop3h 51m

Indianapolis

Sat 1/3

5:45 pm-9:05 pm

1 stop4h 20m

$237

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Mon 12/15

5:45 pm-12:12 am

1 stop5h 27m

Indianapolis

Wed 12/17

6:45 am-10:00 am

1 stop4h 15m

$237

SpringfieldIndianapolis

SGF - IND

SGFIND

Springfield-Branson

Mon 11/17

6:58 pm-12:26 am

1 stop4h 28m

Indianapolis

Mon 11/24

6:00 am-10:53 am

1 stop5h 53m

$244

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 48 results

...

Best time to book a flight from Missouri to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Indianapolis

What is the cheapest month to book a flight from Missouri to Indianapolis?

Currently, December is the cheapest month in which you can book a flight from Missouri to Indianapolis (average of $114). Flying from Missouri to Indianapolis in June is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IND?

One of the essential ways to save on airfare from Missouri to Indianapolis is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 55% on airfare.

How much does it cost to fly round-trip from Missouri to Indianapolis?

Related info for your journey

What airport do you fly into for flights to Indianapolis from Missouri?
Indianapolis (IND) is the airport you will fly into if you book a flight from Missouri to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.
How long is the flight from Missouri to Indianapolis?
Delta, United Airlines, and American Airlines can get you from Missouri to Indianapolis in just under 4h 24m. Your travel time can differ by up to 1h 15m. The distance between Missouri and Indianapolis is about 449 mi. This flight may include one or multiple stops.
What are the cheapest airlines to fly from Missouri to Indianapolis one-way?
For one-way options, check prices for Delta. According to our data, you can fly for as low as $109. Users have also found prices from $112 and $119 on Spirit Airlines and United Airlines, respectively.
What are the most popular routes from Missouri to Indianapolis?
When deciding which route to take from Missouri to Indianapolis consider Kansas City - Indianapolis, Lambert-St Louis - Indianapolis or Springfield-Branson - Indianapolis as they are the most popular.
Can I find deals for flights from Missouri to Indianapolis that include hotel bookings?
Yes. In addition to deals on Missouri to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Indianapolis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Indianapolis.
Can I find deals for business class flights from Missouri to Indianapolis?
Yes. Cheapflights offers flight deals from Missouri to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Indianapolis?
Currently, December is the cheapest month in which you can book a flight from Missouri to Indianapolis (average of $114). Flying from Missouri to Indianapolis in June is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Terre Haute

Muncie

Noblesville

Fishers

Greenwood

Anderson

Kokomo

Bloomington

Plainfield

Franklin

Carmel

Crawfordsville

Speedway

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Top 3 airlines flying from Missouri to Indianapolis

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$178	Average$314	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$204	Average$345	FlexibilityNo cancel fee	On-time63%
United Airlines	Cheapest$226	Average$382	FlexibilityNo cancel fee	On-time69%

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$55+ Cheap flights from Missouri to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Missouri to Indianapolis

Keep the following information in mind while searching for Missouri to Indianapolis flight deals. Data was last updated October 30, 2025.

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Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Missouri to Indianapolis

Cheapest flights from Missouri to IndianapolisExplore the most affordable flight options available from Missouri to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Explore the most affordable flight options available from Missouri to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Indianapolis that are best for you.

Best time to book a flight from Missouri to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Indianapolis

What is the cheapest month to book a flight from Missouri to Indianapolis?

What is the cheapest time of day to fly from MO to IND?

Find hourly flight availability from Missouri to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

How much does it cost to fly round-trip from Missouri to Indianapolis?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Indianapolis from Missouri?

How long is the flight from Missouri to Indianapolis?

What are the cheapest airlines to fly from Missouri to Indianapolis one-way?

What are the most popular routes from Missouri to Indianapolis?

Can I find deals for flights from Missouri to Indianapolis that include hotel bookings?

How can I find direct flights from Missouri to Indianapolis?

Can I find deals for business class flights from Missouri to Indianapolis?

What is the cheapest month to book a flight from Missouri to Indianapolis?

Traveling to a place near Indianapolis?

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Alternative routes for Missouri to Indianapolis

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Top 3 airlines flying from Missouri to Indianapolis

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Cheapest flights from Missouri to Indianapolis
Explore the most affordable flight options available from Missouri to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.