$65+ Cheap flights from Missouri to Indiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — IND
Jun 24 — Jul 11
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to IndianaExplore the most affordable flight options available from Missouri to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 25, 2026.
Explore the most affordable flight options available from Missouri to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:07 pm
MCI
- CVG
1 stop16h 41m
Frontier
Sat 7/1812:53 pm
CVG
- MCI
1 stop5h 17m
Frontier
Deal found 5/20![Frontier logo]()
$170
This Frontier deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:03 pm
STL
- ORD
1 stop10h 34m
Frontier
Wed 8/125:13 pm
ORD
- STL
1 stop6h 46m
Frontier
Deal found 5/23![Frontier logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:33 pm
STL
- ORD
1 stop14h 30m
Frontier
Mon 8/319:48 pm
ORD
- STL
1 stop21h 35m
Frontier
Deal found 5/20![Frontier logo]()
$232
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:38 am
STL
- ORD
Nonstop1h 27m
American Airlines
Thu 10/1511:40 am
ORD
- STL
Nonstop1h 23m
American Airlines
Deal found 5/22![American Airlines logo]()
$233
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/121:29 pm
STL
- ORD
Nonstop1h 31m
United Airlines
Wed 10/2112:45 pm
ORD
- STL
Nonstop1h 26m
United Airlines
Deal found 5/22![United Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:06 pm
STL
- ORD
1 stop14h 57m
Frontier
Tue 6/306:55 am
ORD
- STL
1 stop10h 35m
Frontier
Deal found 5/20![Frontier logo]()
$235
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2212:46 pm
STL
- ORD
1 stop4h 53m
American Airlines
Thu 9/311:29 am
ORD
- STL
Nonstop1h 25m
American Airlines
Deal found 5/21![American Airlines logo]()
$236
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:55 pm
STL
- MDW
Nonstop1h 10m
Southwest
Sat 7/46:30 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 5/20![Southwest logo]()
$237
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:55 am
STL
- ORD
Nonstop1h 28m
American Airlines
Sat 7/183:15 pm
ORD
- STL
Nonstop1h 33m
American Airlines
Deal found 5/23![American Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:23 am
STL
- ORD
1 stop5h 28m
American Airlines
Mon 8/1711:00 pm
ORD
- STL
Nonstop1h 14m
American Airlines
Deal found 5/25![American Airlines logo]()
$238
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:47 pm
COU
- ORD
Nonstop1h 47m
American Airlines
Sun 6/288:30 am
ORD
- COU
Nonstop1h 36m
American Airlines
Deal found 5/24![American Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:06 pm
STL
- MDW
1 stop18h 06m
Frontier
Thu 6/256:00 am
MDW
- STL
1 stop11h 30m
Frontier
Deal found 5/21![Frontier logo]()
$240
Best flights from Missouri to IndianaDiscover carefully curated flight deals from Missouri to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 25, 2026.
Discover carefully curated flight deals from Missouri to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 25, 2026.
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/279:55 pm
STL
- MDW
Nonstop1h 05m
Southwest
Tue 7/289:10 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 5/21![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:20 am
STL
- ORD
Nonstop1h 40m
United Airlines
Wed 7/157:00 am
ORD
- STL
Nonstop1h 34m
United Airlines
Deal found 5/20![United Airlines logo]()
$237
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:30 am
STL
- ORD
1 stop6h 34m
Delta
Fri 6/267:01 am
ORD
- STL
1 stop6h 08m
Delta
Deal found 5/23![Delta logo]()
$257
This KAYAK deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2212:39 pm
STL
- ORD
1 stop7h 06m
American Airlines
Tue 6/2311:00 pm
ORD
- STL
Nonstop1h 16m
American Airlines
Deal found 5/21![American Airlines logo]()
$282
This Booking.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:45 pm
MCI
- CVG
1 stop28h 25m
Frontier
Sat 6/1312:52 pm
CVG
- MCI
1 stop5h 29m
Frontier
Deal found 5/24![Frontier logo]()
$302
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:49 am
COU
- ORD
Nonstop1h 41m
United Airlines
Sun 7/128:40 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 5/20![United Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:35 am
STL
- MDW
1 stop5h 35m
Southwest
Sat 6/206:30 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 5/22![Southwest logo]()
$247
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/198:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Fri 6/268:40 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 5/22![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:30 pm
SGF
- MDW
1 stop6h 15m
Delta
Sat 10/316:00 am
MDW
- SGF
1 stop5h 11m
Delta
Deal found 5/20![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:00 pm
STL
- MDW
Nonstop1h 05m
Southwest
Fri 6/127:50 am
MDW
- STL
Nonstop1h 20m
Southwest
Deal found 5/20![Southwest logo]()
$248
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:39 pm
COU
- ORD
1 stop5h 05m
American Airlines
Sat 6/610:50 am
ORD
- COU
1 stop8h 19m
American Airlines
Deal found 5/20![American Airlines logo]()
$288
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Sun 6/288:40 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 5/20![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:40 am
SGF
- ORD
2 stops8h 44m
Delta
Thu 10/155:30 am
ORD
- SGF
1 stop5h 41m
Delta
Deal found 5/22![Delta logo]()
$274
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Thu 6/2510:00 pm
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 5/21![United Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:40 am
STL
- MDW
1 stop3h 25m
Southwest
Sat 8/296:35 am
MDW
- STL
Nonstop1h 10m
Southwest
Deal found 5/24![Southwest logo]()
$274
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:30 am
STL
- ORD
1 stop4h 12m
Delta
Sat 8/292:27 pm
ORD
- STL
1 stop6h 15m
Delta
Deal found 5/24![Delta logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:07 pm
MCI
- IND
2 stops25h 01m
Frontier
Mon 7/1312:20 pm
IND
- MCI
1 stop5h 50m
Frontier
Deal found 5/24![Frontier logo]()
$366
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Mon 6/88:40 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 5/22![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:45 am
STL
- MDW
1 stop5h 48m
Delta
Sun 10/189:30 am
MDW
- STL
1 stop3h 50m
Delta
Deal found 5/22![Delta logo]()
$297
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:52 pm
MCI
- IND
1 stop4h 00m
American Airlines
Sun 6/285:10 am
IND
- MCI
1 stop4h 25m
American Airlines
Deal found 5/20![American Airlines logo]()
$360
This Southwest deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:20 pm
MCI
- IND
Nonstop1h 25m
Southwest
Mon 8/2410:20 am
IND
- MCI
Nonstop1h 30m
Southwest
Deal found 5/23![Southwest logo]()
$301
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:48 am
COU
- ORD
Nonstop1h 41m
United Airlines
Sat 6/67:25 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 5/20![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:40 am
STL
- MDW
Nonstop1h 05m
Southwest
Tue 6/232:35 pm
MDW
- STL
Nonstop1h 10m
Southwest
Deal found 5/21![Southwest logo]()
$307
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:03 pm
MCI
- CVG
1 stop5h 56m
American Airlines
Sun 8/25:07 am
CVG
- MCI
1 stop7h 17m
American Airlines
Deal found 5/22![American Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:30 am
STL
- MDW
1 stop6h 08m
Delta
Tue 7/219:19 am
MDW
- STL
2 stops7h 27m
Delta
Deal found 5/24![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:55 am
MCI
- CVG
2 stops7h 55m
Southwest
Thu 8/206:00 am
CVG
- MCI
1 stop6h 30m
Southwest
Deal found 5/23![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/121:29 pm
STL
- ORD
Nonstop1h 31m
United Airlines
Mon 10/197:50 pm
ORD
- STL
Nonstop1h 31m
United Airlines
Deal found 5/22![United Airlines logo]()
$296
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:30 am
STL
- ORD
1 stop6h 43m
Delta
Sun 8/302:12 pm
ORD
- STL
2 stops9h 14m
Delta
Deal found 5/21![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:10 pm
MCI
- IND
1 stop3h 40m
Southwest
Tue 7/141:05 pm
IND
- MCI
Nonstop1h 30m
Southwest
Deal found 5/21![Southwest logo]()
$319
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am
STL
- ORD
Nonstop1h 22m
United Airlines
Mon 10/262:20 pm
ORD
- STL
Nonstop1h 18m
United Airlines
Deal found 5/25![United Airlines logo]()
$299
Last-minute flights from Missouri to IndianaDiscover last-minute flight deals from Missouri to Indiana. Data last updated May 25, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Indiana. Data last updated May 25, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:03 pm
STL
- ORD
1 stop11h 04m
Frontier
Tue 6/166:55 am
ORD
- STL
1 stop10h 35m
Frontier
Deal found 5/23![Frontier logo]()
$250
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:00 pm
STL
- MDW
Nonstop1h 05m
Southwest
Fri 6/127:50 am
MDW
- STL
Nonstop1h 20m
Southwest
Deal found 5/20![Southwest logo]()
$248
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:03 pm
STL
- ORD
Nonstop1h 41m
American Airlines
Tue 6/1611:00 pm
ORD
- STL
Nonstop1h 16m
American Airlines
Deal found 5/20![American Airlines logo]()
$248
This Southwest deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/179:30 pm
STL
- MDW
Nonstop1h 05m
Southwest
Sat 6/206:30 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 5/22![Southwest logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:06 pm
STL
- ORD
1 stop14h 57m
Frontier
Fri 6/261:29 pm
ORD
- STL
1 stop19h 23m
Frontier
Deal found 5/20![Frontier logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:06 pm
STL
- MDW
1 stop18h 06m
Frontier
Thu 6/256:00 am
MDW
- STL
1 stop11h 30m
Frontier
Deal found 5/21![Frontier logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/231:45 pm
MCI
- CVG
2 stops21h 04m
Frontier
Fri 6/2612:54 pm
CVG
- MCI
1 stop5h 27m
Frontier
Deal found 5/21![Frontier logo]()
$246
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:32 pm
STL
- ORD
Nonstop1h 27m
American Airlines
Fri 6/267:05 am
ORD
- STL
Nonstop1h 26m
American Airlines
Deal found 5/24![American Airlines logo]()
$237
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:54 am
JLN
- ORD
Nonstop1h 58m
United Airlines
Mon 6/2911:32 am
ORD
- JLN
Nonstop1h 50m
United Airlines
Deal found 5/23![United Airlines logo]()
$241
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:30 am
STL
- ORD
1 stop6h 34m
Delta
Fri 6/267:01 am
ORD
- STL
1 stop6h 08m
Delta
Deal found 5/20![Delta logo]()
$257
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:30 am
STL
- MDW
1 stop6h 16m
Delta
Fri 6/269:17 am
MDW
- STL
1 stop3h 52m
Delta
Deal found 5/20![Delta logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:06 pm
STL
- ORD
1 stop14h 57m
Frontier
Tue 6/306:55 am
ORD
- STL
1 stop10h 35m
Frontier
Deal found 5/20![Frontier logo]()
$235
One-way flights from Missouri to IndianaSearch for one-way flight options from Missouri to Indiana. Find affordable one-way fares based on user searches. Data last updated May 25, 2026.
Search for one-way flight options from Missouri to Indiana. Find affordable one-way fares based on user searches. Data last updated May 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:31 pm
STL
- ORD
1 stop13h 32m
Frontier
Deal found 5/20![Frontier logo]()
$65
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/169:30 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 5/20![Southwest logo]()
$69
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:03 am
STL
- ORD
Nonstop1h 27m
American Airlines
Deal found 5/24![American Airlines logo]()
$69
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:30 am
STL
- MDW
1 stop6h 16m
Delta
Deal found 5/20![Delta logo]()
$79
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:18 pm
STL
- ORD
1 stop6h 06m
Delta
Deal found 5/20![Delta logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/225:06 pm
STL
- ORD
1 stop14h 57m
Frontier
Deal found 5/20![Frontier logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:52 pm
STL
- MDW
1 stop29h 19m
Frontier
Deal found 5/20![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:52 pm
STL
- MDW
1 stop29h 11m
Frontier
Deal found 5/20![Frontier logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:31 pm
STL
- ORD
1 stop13h 32m
Frontier
Deal found 5/20![Frontier logo]()
$95
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1711:05 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 5/21![Southwest logo]()
$96
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:06 pm
STL
- ORD
Nonstop1h 34m
American Airlines
Deal found 5/21![American Airlines logo]()
$96
This Southwest deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/72:20 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 5/22![Southwest logo]()
$98
Find flight deals from Missouri to Indiana
Keep the following information in mind while searching for Missouri to Indiana flight deals. Data was last updated May 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $170 (Kiwi.com) |
One-way from | $65 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $543 |
Good round-trip deal | $421 or less |
Good one-way deal | $325 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 25, 2026.
Use the filters below to find and compare flights from Missouri to Indiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisChicago
STL - MDW
STLMDW
Lambert-St Louis
Mon 7/27
9:55 pm-11:00 pm
Nonstop1h 05m
Chicago Midway
Tue 7/28
9:10 pm-10:25 pm
Nonstop1h 15m
$237
St. LouisChicago
STL - ORD
STLORD
Lambert-St Louis
Mon 7/13
7:20 am-9:00 am
Nonstop1h 40m
Chicago O'Hare Intl
Wed 7/15
7:00 am-8:34 am
Nonstop1h 34m
$237
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Thu 7/9
10:49 am-12:30 pm
Nonstop1h 41m
Chicago O'Hare Intl
Sun 7/12
8:40 am-10:13 am
Nonstop1h 33m
$239
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Fri 6/19
8:00 am-9:40 am
Nonstop1h 40m
Chicago O'Hare Intl
Fri 6/26
8:40 am-10:13 am
Nonstop1h 33m
$239
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Sat 6/27
8:00 am-9:40 am
Nonstop1h 40m
Chicago O'Hare Intl
Sun 6/28
8:40 am-10:13 am
Nonstop1h 33m
$239
St. LouisChicago
STL - MDW
STLMDW
Lambert-St Louis
Wed 6/17
8:35 am-2:10 pm
1 stop5h 35m
Chicago Midway
Sat 6/20
6:30 am-7:45 am
Nonstop1h 15m
$247
St. LouisChicago
STL - MDW
STLMDW
Lambert-St Louis
Wed 6/10
4:00 pm-5:05 pm
Nonstop1h 05m
Chicago Midway
Fri 6/12
7:50 am-9:10 am
Nonstop1h 20m
$248
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Thu 6/18
8:00 am-9:40 am
Nonstop1h 40m
Chicago O'Hare Intl
Thu 6/25
10:00 pm-11:33 pm
Nonstop1h 33m
$249
St. LouisChicago
STL - ORD
STLORD
Lambert-St Louis
Wed 6/24
6:30 am-1:04 pm
1 stop6h 34m
Chicago O'Hare Intl
Fri 6/26
7:01 am-1:09 pm
1 stop6h 08m
$257
SpringfieldChicago
SGF - MDW
SGFMDW
Springfield-Branson
Thu 10/29
3:30 pm-9:45 pm
1 stop6h 15m
Chicago Midway
Sat 10/31
6:00 am-11:11 am
1 stop5h 11m
$269
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from Missouri with our price prediction graph.
MCI-CVG
STL-ORD
STL-MDW
COU-ORD
SGF-MDW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Indiana
USMO-USIN
MCI-CVG
STL-ORD
STL-MDW
COU-ORD
What is the cheapest month to book a flight from Missouri to Indiana?
Currently, December is the cheapest month in which you can book a flight from Missouri to Indiana (average of $55). Flying from Missouri to Indiana in April is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to IN?
Find hourly flight availability from Missouri to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 25, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Indiana as you normally would.
How much does it cost to fly round-trip from Missouri to Indiana?
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated May 25, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Missouri to Indiana by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Missouri to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to Indiana
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indiana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Indiana by cabin class
Find flights from Missouri to Indiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Indiana flights
Browse other Missouri and Indiana flight options. Last updated on May 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Indiana
Find the right flight back to Missouri after your stay in Indiana
Missouri to Indiana flights
Consider these flights traveling from Missouri to Indiana.
Top 4 airlines flying from Missouri to Indiana
Discover the top 4 airlines that operate flights from Missouri to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$382 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$194 | Average$375 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$204 | Average$291 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$204 | Average$342 | FlexibilityNo cancel fee | On-time69% |