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$68+ Cheap flights from Indianapolis (IND) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/17. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
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Cheap flight deals from Indianapolis to Missouri

Keep the following information in mind while searching for Indianapolis to Missouri flight deals. Data was last updated January 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$160
(Kiwi.com)

One-way from

$68
(Kiwi.com)

Popular in

September

Cheapest in

November

Average price

$386

Good round-trip deal

$391 or less

Good one-way deal

$264 or less
Provider with most accurate pricing for Indianapolis-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Lambert-St Louis flights.
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From Indianapolis to Missouri
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One-way flight from Indianapolis to Missouri
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Highest demand for flights based on searches. 8% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Price to beat on a round-trip flight from Indianapolis to Missouri.
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Price to beat on a one-way flight from Indianapolis to Missouri.
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Find flight deals from Indianapolis to Missouri

Cheapest flights from Indianapolis to Missouri
Explore the most affordable flight options available from Indianapolis to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:27 pm
IND
-
MCI
1 stop15h 36m
Frontier
Mon 2/2310:55 am
MCI
-
IND
1 stop6h 36m
Frontier
Deal found 1/13$160
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:47 pm
IND
-
MCI
1 stop23h 59m
Frontier
Fri 2/2011:00 am
MCI
-
IND
1 stop6h 31m
Frontier
Deal found 1/13$180
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:47 pm
IND
-
MCI
1 stop23h 59m
Multiple Airlines
Wed 2/184:24 pm
MCI
-
IND
1 stop15h 08m
Multiple Airlines
Deal found 1/13$186
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:47 pm
IND
-
MCI
1 stop23h 59m
Multiple Airlines
Tue 2/174:24 pm
MCI
-
IND
1 stop15h 08m
Multiple Airlines
Deal found 1/13$188
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:47 pm
IND
-
MCI
1 stop23h 59m
Multiple Airlines
Thu 2/1911:26 am
MCI
-
IND
1 stop10h 22m
Multiple Airlines
Deal found 1/13$190
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:47 pm
IND
-
MCI
1 stop23h 59m
Frontier
Wed 2/254:39 pm
MCI
-
IND
1 stop26h 18m
Frontier
Deal found 1/15$191
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/109:13 pm
IND
-
MCI
1 stop19h 56m
Multiple Airlines
Fri 2/2011:00 am
MCI
-
IND
1 stop6h 31m
Multiple Airlines
Deal found 1/13$192
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/109:13 pm
IND
-
MCI
1 stop19h 56m
Multiple Airlines
Wed 2/184:24 pm
MCI
-
IND
1 stop15h 08m
Multiple Airlines
Deal found 1/13$198
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:18 pm
IND
-
MCI
1 stop15h 12m
Multiple Airlines
Sun 3/88:40 pm
MCI
-
IND
1 stop21h 58m
Multiple Airlines
Deal found 1/14$200
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:47 pm
IND
-
MCI
1 stop23h 59m
Multiple Airlines
Wed 2/257:00 am
MCI
-
IND
2 stops26h 20m
Multiple Airlines
Deal found 1/15$201
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/109:13 pm
IND
-
MCI
1 stop19h 56m
Multiple Airlines
Thu 2/1911:26 am
MCI
-
IND
1 stop10h 22m
Multiple Airlines
Deal found 1/13$202
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/109:13 pm
IND
-
MCI
1 stop19h 56m
Multiple Airlines
Sun 2/1510:14 am
MCI
-
IND
1 stop7h 20m
Multiple Airlines
Deal found 1/13$204

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Indianapolis to Missouri that are best for you.

Fly from

Indianapolis

Fly to

Missouri

Route

Depart

Return

Price

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Wed 2/11

1:23 pm-3:29 pm

1 stop27h 06m

Kansas City

Wed 2/18

4:39 pm-8:07 pm

1 stop26h 28m

$211

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Tue 3/17

12:54 pm-5:00 pm

1 stop5h 06m

Kansas City

Wed 3/18

12:17 pm-7:18 pm

1 stop6h 01m

$213

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Wed 3/11

7:59 pm-11:03 pm

1 stop4h 04m

Kansas City

Mon 3/16

5:40 pm-11:47 pm

1 stop5h 07m

$234

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Tue 3/3

5:45 pm-9:07 pm

1 stop4h 22m

Kansas City

Mon 3/9

12:17 pm-7:18 pm

1 stop6h 01m

$234

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Tue 3/17

12:54 pm-5:00 pm

1 stop5h 06m

Kansas City

Fri 3/20

5:40 pm-11:47 pm

1 stop5h 07m

$234

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Tue 3/3

4:40 pm-11:00 pm

1 stop7h 20m

Kansas City

Sat 3/7

6:23 am-11:40 am

1 stop4h 17m

$234

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Sat 3/14

7:05 am-11:37 am

1 stop5h 32m

Kansas City

Tue 3/17

5:42 pm-12:02 am

1 stop5h 20m

$234

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Tue 3/17

7:59 pm-11:03 pm

1 stop4h 04m

Kansas City

Mon 3/23

5:40 pm-11:47 pm

1 stop5h 07m

$234

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Thu 2/19

5:49 am-10:12 am

1 stop5h 23m

Kansas City

Mon 2/23

6:40 am-2:56 pm

1 stop7h 16m

$235

IndianapolisSt. Louis

IND - STL

INDSTL

Indianapolis

Thu 1/29

12:38 pm-6:51 am

1 stop19h 13m

Lambert-St Louis

Mon 2/2

8:22 pm-11:26 am

2 stops38h 04m

$243

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/15

Showing 1-10 of 48 results
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Best time to book a flight from Indianapolis to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Missouri

What is the cheapest month to book a flight from Indianapolis to Missouri?

Currently, September is the cheapest month in which you can book a flight from Indianapolis to Missouri (average of $75). Flying from Indianapolis to Missouri in December is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to MO?

Find hourly flight availability from Indianapolis to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 15, 2026.

Unlike in the evening, when flights are generally more expensive, you can save up to 80% on flights from Indianapolis to Missouri by exploring options for tickets in the morning.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 15, 2026.
Read through reviews of airlines operating flights from Indianapolis to Missouri, such as Southwest, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,258 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,258 reviews
Southwest
8.0
Very good
4,258 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,163 reviews
Southwest
8.0
Very good
4,258 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,129 reviews
Southwest
8.0
Very good
4,258 reviews

Crew

8.6

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Missouri?

    Most people fly from Indianapolis (IND) if they book a flight from Indianapolis to Missouri. Indianapolis is conveniently located just 8.3 mi from Indianapolis’s city center.

  • How long is the flight from Indianapolis to Missouri?

    For as low as $213, Delta can have you in Missouri from Indianapolis in 5h 06m. There are 449 mi between Indianapolis and Missouri. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Indianapolis to Missouri one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $98. Users have also found prices from $118 and $143 on Southwest and Delta, respectively.

  • What are the most popular routes from Indianapolis to Missouri?

    Most travelers choose Indianapolis - Kansas City, Indianapolis - Springfield-Branson or Indianapolis - Lambert-St Louis when deciding on the best route from Indianapolis to Missouri.

  • Can I find deals for flights from Indianapolis to Missouri that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Missouri.

  • Can I find deals for business class flights from Indianapolis to Missouri?

    Yes. Cheapflights offers flight deals from Indianapolis to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Indianapolis to Missouri (average of $75). Flying from Indianapolis to Missouri in December is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indianapolis to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Indianapolis to Missouri

Discover the top 3 airlines that operate flights from Indianapolis to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$178Average$408FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$221Average$331FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$239Average$343FlexibilityNo cancel feeOn-time69%

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