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Illinois

$79+ Cheap flights from Des Moines (DSM) to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ORD
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Des Moines to Illinois

Cheapest flights from Des Moines to Illinois
Explore the most affordable flight options available from Des Moines to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:52 pmDSM - STL
1 stop4h 52mAmerican Airlines
Sat 1/38:01 pmSTL - DSM
1 stop3h 50mAmerican Airlines
Deal found 12/15$159
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:52 pmDSM - ORD
Nonstop1h 51mAmerican Airlines
Sat 1/311:25 amORD - DSM
Nonstop1h 29mAmerican Airlines
Deal found 12/13$204
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:55 pmDSM - STL
1 stop4h 21mDelta
Wed 1/76:35 amSTL - DSM
1 stop4h 49mDelta
Deal found 12/13$209
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:57 pmDSM - ORD
Nonstop1h 51mAmerican Airlines
Mon 12/296:40 amORD - DSM
Nonstop1h 35mAmerican Airlines
Deal found 12/13$219
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:50 amDSM - ORD
Nonstop1h 40mAmerican Airlines
Tue 1/272:50 pmORD - DSM
Nonstop1h 34mAmerican Airlines
Deal found 12/13$234
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:00 amDSM - ORD
Nonstop1h 38mUnited Airlines
Tue 12/304:31 pmORD - DSM
Nonstop1h 34mUnited Airlines
Deal found 12/14$249
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:29 amDSM - MDW
1 stop6h 57mDelta
Tue 1/279:50 amMDW - DSM
1 stop5h 51mDelta
Deal found 12/14$254
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:29 amDSM - ORD
1 stop6h 53mDelta
Tue 1/276:15 amORD - DSM
1 stop4h 36mDelta
Deal found 12/13$254
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:55 pmDSM - STL
1 stop4h 21mDelta
Thu 1/16:05 amSTL - DSM
1 stop5h 23mDelta
Deal found 12/15$259
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:40 amDSM - ORD
Nonstop1h 40mAmerican Airlines
Thu 1/159:40 amORD - DSM
Nonstop1h 32mAmerican Airlines
Deal found 12/13$263
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:40 amDSM - ORD
Nonstop1h 40mAmerican Airlines
Fri 1/21:29 pmORD - DSM
Nonstop1h 24mAmerican Airlines
Deal found 12/13$278
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:00 amDSM - ORD
Nonstop1h 38mUnited Airlines
Thu 12/258:10 pmORD - DSM
Nonstop1h 30mUnited Airlines
Deal found 12/14$279

Find flight deals from Des Moines to Illinois

Keep the following information in mind while searching for Des Moines to Illinois flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$159
(Delta)

One-way from

$79
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$290

Good round-trip deal

$387 or less

Good one-way deal

$284 or less
Provider with most accurate pricing for Des Moines-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Chicago (CHI) flights.
Search Deals
From Des Moines to Illinois
Search Deals
One-way flight from Des Moines to Illinois
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($13 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Des Moines to Illinois.
Search Deals
Price to beat on a one-way flight from Des Moines to Illinois.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Des Moines to Illinois that are best for you.

Fly from

Des Moines

Fly to

Illinois

Route

Depart

Return

Price

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 1/27

10:30 am-4:45 pm

1 stop6h 15m

Lambert-St Louis

Tue 2/3

3:31 pm-9:24 pm

1 stop5h 53m

$159

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 12/30

6:52 pm-11:44 pm

1 stop4h 52m

Lambert-St Louis

Sat 1/3

8:01 pm-11:51 pm

1 stop3h 50m

$159

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Thu 1/22

10:59 am-2:38 pm

1 stop3h 39m

Lambert-St Louis

Mon 1/26

3:45 pm-10:29 pm

1 stop6h 44m

$159

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 1/23

5:16 pm-11:37 pm

1 stop6h 21m

Lambert-St Louis

Sun 1/25

6:00 am-10:41 am

1 stop4h 41m

$159

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 2/17

10:57 am-8:43 pm

2 stops9h 46m

Lambert-St Louis

Thu 2/19

6:10 am-10:17 am

1 stop4h 07m

$164

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Tue 1/6

6:48 pm-8:21 pm

Nonstop1h 33m

Chicago O'Hare Intl

Mon 1/12

8:20 pm-9:50 pm

Nonstop1h 30m

$189

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Mon 1/5

3:27 pm-5:06 pm

Nonstop1h 39m

Chicago O'Hare Intl

Wed 1/7

7:35 pm-9:04 pm

Nonstop1h 29m

$189

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Sat 1/24

5:01 pm-6:48 pm

Nonstop1h 47m

Chicago O'Hare Intl

Fri 1/30

9:40 am-11:12 am

Nonstop1h 32m

$189

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Thu 1/22

7:00 am-8:44 am

Nonstop1h 44m

Chicago O'Hare Intl

Mon 1/26

9:40 am-11:12 am

Nonstop1h 32m

$189

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Tue 1/27

11:42 am-1:18 pm

Nonstop1h 36m

Chicago O'Hare Intl

Tue 2/3

9:40 am-11:12 am

Nonstop1h 32m

$190

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 58 results
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Best time to book a flight from Des Moines to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Illinois

What is the cheapest month to book a flight from Des Moines to Illinois?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Illinois (average of $189). Flying from Des Moines to Illinois in January is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IL?

Find hourly flight availability from Des Moines to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

One of the essential ways to save on airfare from Des Moines to Illinois is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 50% on airfare.

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated December 15, 2025.
Get a feel of what it's like to fly with Southwest, United Airlines, and American Airlines from Des Moines to Illinois by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,250 reviews
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,095 reviews
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,048 reviews
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Illinois?

    If you book a flight to Illinois from Des Moines, you will be flying from Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • How long is the flight from Des Moines to Illinois?

    Airlines like Delta, American Airlines, and United Airlines fly from Des Moines to Illinois in about 1h 33m. The time it takes to get you to your destination can typically vary by up to 4h 42m. Des Moines and Illinois are separated by a distance of 298 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Des Moines to Illinois one-way?

    One-way options have recently been found by users for as low as $94 on American Airlines. Other airlines that offer cheap prices include Southwest from $98 and United Airlines from $124 one-way.

  • What are the most popular routes from Des Moines to Illinois?

    The most popular route from Des Moines to Illinois is Des Moines - Chicago O'Hare Intl. You may also consider Des Moines - Chicago Midway or Des Moines - Lambert-St Louis.

  • What are the most reliable airlines from Des Moines to Illinois?

    No one likes to see their flight delayed. When booking a flight from Des Moines to Illinois consider choosing Envoy Air (90%), Copa Airlines (84%) or Japan Airlines (78%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Des Moines to Illinois?

    While on average a flight from Des Moines to Illinois is generally $1,184, our data shows the cheapest flight currently is $167. When looking at the most popular route, (Des Moines - Chicago O'Hare Intl), you can expect to pay $189 for that flight.

  • Can I find deals for flights from Des Moines to Illinois that include hotel bookings?

    Yes. In addition to deals on Des Moines to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Illinois.

  • Can I find deals for business class flights from Des Moines to Illinois?

    Yes. Cheapflights offers flight deals from Des Moines to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Illinois?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Illinois (average of $189). Flying from Des Moines to Illinois in January is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Illinois

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Des Moines to Illinois

Discover the top 2 airlines that operate flights from Des Moines to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$189Average$249FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$189Average$254FlexibilityNo cancel feeOn-time69%

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