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$49+ Cheap flights from Des Moines (DSM) to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ORD
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Des Moines to Illinois

Keep the following information in mind while searching for Des Moines to Illinois flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$120
(Mytrip)

One-way from

$49
(Southwest)

Popular in

October

Cheapest in

September

Average price

$284

Good round-trip deal

$323 or less

Good one-way deal

$213 or less
Provider with most accurate pricing for Des Moines-Chicago (CHI) flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Chicago (CHI) flights.
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From Des Moines to Illinois
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One-way flight from Des Moines to Illinois
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Des Moines to Illinois.
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Price to beat on a one-way flight from Des Moines to Illinois.
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Find flight deals from Des Moines to Illinois

Cheapest flights from Des Moines to Illinois
Explore the most affordable flight options available from Des Moines to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/102:32 pmDSM - STL
1 stop18h 35mFrontier
Wed 11/127:45 pmSTL - DSM
1 stop18h 11mFrontier
Deal found 10/27$120
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:15 amDSM - STL
Nonstop1h 10mSouthwest
Sat 12/131:45 pmSTL - DSM
Nonstop1h 10mSouthwest
Deal found 10/26$154
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:34 amDSM - STL
1 stop5h 11mDelta
Thu 12/186:00 amSTL - DSM
1 stop4h 38mDelta
Deal found 10/27$157
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:34 amDSM - STL
1 stop5h 11mDelta
Sat 12/1310:45 amSTL - DSM
1 stop6h 13mDelta
Deal found 10/26$169
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:41 amDSM - ORD
Nonstop1h 42mAmerican Airlines
Sun 11/236:50 amORD - DSM
Nonstop1h 31mAmerican Airlines
Deal found 10/28$189
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:40 amDSM - ORD
Nonstop1h 43mAmerican Airlines
Thu 12/181:57 pmORD - DSM
Nonstop1h 27mAmerican Airlines
Deal found 10/27$190
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/32:32 pmDSM - ORD
1 stop9h 43mFrontier
Wed 11/56:05 pmORD - DSM
1 stop19h 51mFrontier
Deal found 10/27$192
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/122:19 pmDSM - ORD
Nonstop1h 43mAmerican Airlines
Sun 11/167:00 amORD - DSM
Nonstop1h 32mAmerican Airlines
Deal found 10/26$194
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:58 pmDSM - STL
1 stop14h 16mFrontier
Sun 12/710:42 amSTL - DSM
2 stops32h 21mFrontier
Deal found 10/27$195
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:58 pmDSM - STL
1 stop14h 16mFrontier
Fri 12/197:43 pmSTL - DSM
1 stop24h 01mFrontier
Deal found 10/28$196
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/112:19 pmDSM - ORD
Nonstop1h 43mAmerican Airlines
Sat 11/154:40 pmORD - DSM
Nonstop1h 30mAmerican Airlines
Deal found 10/27$199
This Frontier deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/142:34 pmDSM - ORD
1 stop9h 41mFrontier
Sun 11/166:00 amORD - DSM
1 stop7h 47mFrontier
Deal found 10/28$202

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Des Moines to Illinois that are best for you.

Fly from

Des Moines

Fly to

Illinois

Route

Depart

Return

Price

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Thu 12/11

6:15 am-7:25 am

Nonstop1h 10m

Lambert-St Louis

Sat 12/13

1:45 pm-2:55 pm

Nonstop1h 10m

$154

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 3/3

5:15 pm-11:40 pm

1 stop6h 25m

Lambert-St Louis

Wed 3/4

6:30 am-10:22 am

1 stop3h 52m

$157

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Thu 12/11

5:34 am-10:45 am

1 stop5h 11m

Lambert-St Louis

Sat 12/13

10:45 am-4:58 pm

1 stop6h 13m

$169

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 12/5

7:58 pm-10:14 am

1 stop14h 16m

Lambert-St Louis

Sun 12/7

10:42 am-7:03 pm

2 stops32h 21m

$195

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 12/12

7:58 pm-10:14 am

1 stop14h 16m

Lambert-St Louis

Fri 12/19

7:43 pm-7:44 pm

1 stop24h 01m

$196

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Thu 12/11

6:50 am-1:53 pm

2 stops7h 03m

Lambert-St Louis

Thu 12/18

6:00 am-1:31 pm

1 stop7h 31m

$198

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Thu 1/29

3:20 pm-7:05 pm

1 stop3h 45m

Chicago Midway

Mon 2/2

6:10 am-11:25 am

1 stop5h 15m

$209

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Tue 12/16

6:15 am-11:25 am

1 stop5h 10m

Chicago Midway

Tue 12/16

5:15 pm-9:35 pm

1 stop4h 20m

$209

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Thu 12/11

6:17 am-12:34 pm

1 stop6h 17m

Chicago Midway

Thu 12/18

9:59 am-5:03 pm

1 stop7h 04m

$209

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Fri 12/5

6:17 am-12:34 pm

1 stop6h 17m

Chicago Midway

Sun 12/7

9:34 am-4:16 pm

1 stop6h 42m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 57 results
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Best time to book a flight from Des Moines to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Illinois

What is the cheapest month to book a flight from Des Moines to Illinois?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Illinois (average of $189). Flying from Des Moines to Illinois in January is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IL?

Find hourly flight availability from Des Moines to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

One of the essential ways to save on airfare from Des Moines to Illinois is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 64% on airfare.

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated October 29, 2025.
Get a feel of what it's like to fly with Southwest, United Airlines, and American Airlines from Des Moines to Illinois by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,999 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Illinois?

    If you book a flight to Illinois from Des Moines, you will be flying from Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • How long is the flight from Des Moines to Illinois?

    Airlines like Southwest, Delta, and American Airlines fly from Des Moines to Illinois in about 1h 10m. The time it takes to get you to your destination can typically vary by up to 5h 15m. Des Moines and Illinois are separated by a distance of 259 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Des Moines to Illinois one-way?

    One-way options have recently been found by users for as low as $49 on Southwest. Other airlines that offer cheap prices include Frontier from $61 and Delta from $105 one-way.

  • What are the most popular routes from Des Moines to Illinois?

    The most popular route from Des Moines to Illinois is Des Moines - Chicago O'Hare Intl. You may also consider Des Moines - Chicago Midway or Des Moines - Lambert-St Louis.

  • What are the most reliable airlines from Des Moines to Illinois?

    No one likes to see their flight delayed. When booking a flight from Des Moines to Illinois consider choosing GoJet (100%), Republic Airways (89%) or Avianca (89%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Des Moines to Illinois?

    While on average a flight from Des Moines to Illinois is generally $825, our data shows the cheapest flight currently is $148. When looking at the most popular route, (Des Moines - Chicago O'Hare Intl), you can expect to pay $189 for that flight.

  • Can I find deals for flights from Des Moines to Illinois that include hotel bookings?

    Yes. In addition to deals on Des Moines to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Illinois.

  • Can I find deals for business class flights from Des Moines to Illinois?

    Yes. Cheapflights offers flight deals from Des Moines to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Illinois?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Illinois (average of $189). Flying from Des Moines to Illinois in January is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Des Moines to Illinois

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Des Moines to Illinois

Discover the top 2 airlines that operate flights from Des Moines to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$189Average$246FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$189Average$256FlexibilityNo cancel feeOn-time69%

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