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$65+ Cheap flights from Des Moines (DSM) to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ORD
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Des Moines to Illinois

Keep the following information in mind while searching for Des Moines to Illinois flight deals. Data was last updated September 11, 2025.

Round-trip from

$157
(Southwest)

One-way from

$65
(Southwest)

Popular in

August

Cheapest in

May

Average price

$224

Good round-trip deal

$346 or less

Good one-way deal

$220 or less
From Des Moines to Illinois
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One-way flight from Des Moines to Illinois
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Highest demand for flights based on searches. 3% potential increase in price ($9 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Des Moines to Illinois.
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Price to beat on a one-way flight from Des Moines to Illinois.
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Find flight deals from Des Moines to Illinois

Cheapest flights from Des Moines to Illinois
Explore the most affordable flight options available from Des Moines to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/84:45 pmDSM - STL
Nonstop1h 10mSouthwest
Thu 10/910:20 pmSTL - DSM
Nonstop1h 10mSouthwest
Deal found 9/10$157
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/224:45 pmDSM - STL
Nonstop1h 10mSouthwest
Thu 10/2310:20 pmSTL - DSM
Nonstop1h 10mSouthwest
Deal found 9/10$164
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2211:06 amDSM - STL
1 stop5h 40mDelta
Sun 10/266:00 amSTL - DSM
1 stop4h 26mDelta
Deal found 9/11$177
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:00 amDSM - ORD
Nonstop1h 28mAmerican Airlines
Sun 10/56:45 amORD - DSM
Nonstop1h 24mAmerican Airlines
Deal found 9/10$189
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/222:37 pmDSM - STL
1 stop18h 30mMultiple Airlines
Thu 10/237:52 pmSTL - DSM
2 stops21h 07mMultiple Airlines
Deal found 9/10$189
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/308:25 amDSM - MDW
2 stops9h 00mSouthwest
Wed 10/16:00 amMDW - DSM
1 stop8h 40mSouthwest
Deal found 9/10$190
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2511:58 amDSM - ORD
Nonstop1h 33mAmerican Airlines
Sat 11/18:35 pmORD - DSM
Nonstop1h 30mAmerican Airlines
Deal found 9/10$190
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:39 pmDSM - STL
1 stop5h 02mDelta
Fri 10/314:45 pmSTL - DSM
1 stop4h 18mDelta
Deal found 9/9$191
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/247:03 amDSM - ORD
Nonstop1h 31mAmerican Airlines
Thu 10/96:55 amORD - DSM
Nonstop1h 27mAmerican Airlines
Deal found 9/9$194
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:00 amDSM - ORD
1 stop9h 45mSouthwest
Tue 9/307:00 amORD - DSM
1 stop7h 40mSouthwest
Deal found 9/10$195
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/144:45 pmDSM - MDW
1 stop5h 20mSouthwest
Thu 10/167:40 amMDW - DSM
1 stop3h 20mSouthwest
Deal found 9/11$196
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:36 pmDSM - ORD
Nonstop1h 34mUnited Airlines
Sun 9/284:00 pmORD - DSM
Nonstop1h 24mUnited Airlines
Deal found 9/10$199

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Des Moines to Illinois that are best for you.

Fly from

Des Moines

Fly to

Illinois

Route

Depart

Return

Price

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Mon 11/3

6:15 am-7:25 am

Nonstop1h 10m

Lambert-St Louis

Mon 11/3

10:15 am-11:25 am

Nonstop1h 10m

$157

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Wed 10/8

4:45 pm-5:55 pm

Nonstop1h 10m

Lambert-St Louis

Thu 10/9

10:20 pm-11:30 pm

Nonstop1h 10m

$157

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 11/14

6:33 pm-11:40 pm

1 stop5h 07m

Lambert-St Louis

Sat 11/15

5:34 pm-9:04 pm

1 stop3h 30m

$177

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Mon 11/3

8:02 am-12:28 pm

1 stop4h 26m

Lambert-St Louis

Mon 11/3

5:24 pm-9:32 pm

1 stop4h 08m

$177

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 9/30

5:25 pm-11:09 pm

1 stop5h 44m

Lambert-St Louis

Thu 10/2

1:26 pm-5:45 pm

1 stop4h 19m

$177

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Wed 10/22

5:32 pm-11:07 pm

1 stop5h 35m

Lambert-St Louis

Thu 10/23

6:00 am-10:26 am

1 stop4h 26m

$177

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Wed 10/22

11:06 am-4:46 pm

1 stop5h 40m

Lambert-St Louis

Sun 10/26

6:00 am-10:26 am

1 stop4h 26m

$177

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Thu 10/23

6:05 am-1:22 pm

1 stop7h 17m

Lambert-St Louis

Sun 10/26

6:00 am-10:26 am

1 stop4h 26m

$177

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Wed 10/22

2:37 pm-9:07 am

1 stop18h 30m

Lambert-St Louis

Thu 10/23

7:52 pm-4:59 pm

2 stops21h 07m

$189

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Fri 10/10

6:36 pm-8:10 pm

Nonstop1h 34m

Chicago O'Hare Intl

Sun 10/12

9:05 am-10:32 am

Nonstop1h 27m

$189

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Illinois

What is the cheapest month to book a flight from Des Moines to Illinois?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Illinois (average of $245). Flying from Des Moines to Illinois in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IL?

Find hourly flight availability from Des Moines to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Illinois as you normally would.

Weekly flight availability from Des Moines to Illinois

Explore weekly flight availability from Des Moines to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 11, 2025.

The most flights from DSM to USIL are scheduled on a Monday (46 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (24 on average).

How much does it cost to fly round-trip from Des Moines to Illinois?

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with Southwest, United Airlines, and American Airlines from Des Moines to Illinois by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,937 reviews
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Illinois?

    If you book a flight to Illinois from Des Moines, you will be flying from Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • How long is the flight from Des Moines to Illinois?

    Airlines like Southwest, Delta, and United Airlines fly from Des Moines to Illinois in about 1h 10m. The time it takes to get you to your destination can typically vary by up to 3h 57m. Des Moines and Illinois are separated by a distance of 259 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Des Moines to Illinois one-way?

    One-way options have recently been found by users for as low as $65 on Southwest. Other airlines that offer cheap prices include Frontier from $82 and Delta from $89 one-way.

  • What are the most popular routes from Des Moines to Illinois?

    The most popular route from Des Moines to Illinois is Des Moines - Chicago O'Hare Intl. You may also consider Des Moines - Chicago Midway or Des Moines - Lambert-St Louis.

  • What are the most reliable airlines from Des Moines to Illinois?

    No one likes to see their flight delayed. When booking a flight from Des Moines to Illinois consider choosing GoJet (100%), Avianca (84%) or Qatar Airways (79%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Des Moines to Illinois?

    While on average a flight from Des Moines to Illinois is generally $1,013, our data shows the cheapest flight currently is $125. When looking at the most popular route, (Des Moines - Chicago O'Hare Intl), you can expect to pay $156 for that flight.

  • Can I find deals for flights from Des Moines to Illinois that include hotel bookings?

    Yes. In addition to deals on Des Moines to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Illinois.

  • Can I find deals for business class flights from Des Moines to Illinois?

    Yes. Cheapflights offers flight deals from Des Moines to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Illinois?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Illinois (average of $245). Flying from Des Moines to Illinois in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Des Moines to Illinois

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Des Moines to Illinois

Discover the top 2 airlines that operate flights from Des Moines to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$189Average$240FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$189Average$254FlexibilityNo cancel feeOn-time69%

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