$59+ Cheap flights from Des Moines (DSM) to Illinois
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ORD
Feb 27 — Mar 61
1 adult, Economy
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Cheapest flights from Des Moines to IllinoisExplore the most affordable flight options available from Des Moines to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.
Explore the most affordable flight options available from Des Moines to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/243:20 pm
DSM
- STL
Nonstop1h 15m
Southwest
Tue 3/38:00 pm
STL
- DSM
Nonstop1h 10m
Southwest
Deal found 1/27![Southwest logo]()
$97
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/101:55 pm
DSM
- STL
1 stop7h 40m
Southwest
Wed 3/114:00 pm
STL
- DSM
1 stop6h 05m
Southwest
Deal found 1/27![Southwest logo]()
$117
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:55 pm
DSM
- ORD
Nonstop1h 36m
United Airlines
Wed 3/49:15 am
ORD
- DSM
Nonstop1h 38m
United Airlines
Deal found 1/28![United Airlines logo]()
$157
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:57 am
DSM
- STL
1 stop5h 48m
Delta
Tue 3/36:00 am
STL
- DSM
1 stop5h 19m
Delta
Deal found 1/27![Delta logo]()
$157
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/94:20 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Tue 3/1010:15 am
MDW
- DSM
Nonstop1h 25m
Southwest
Deal found 1/27![Southwest logo]()
$164
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:44 pm
DSM
- ORD
Nonstop1h 35m
American Airlines
Tue 3/108:59 pm
ORD
- DSM
Nonstop1h 35m
American Airlines
Deal found 1/27![American Airlines logo]()
$164
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:20 pm
DSM
- MDW
1 stop3h 45m
Southwest
Tue 3/1710:15 am
MDW
- DSM
Nonstop1h 25m
Southwest
Deal found 1/27![Southwest logo]()
$167
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:35 am
DSM
- MDW
Nonstop1h 20m
Southwest
Mon 4/209:45 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 1/26![Southwest logo]()
$171
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:00 am
DSM
- ORD
Nonstop1h 29m
American Airlines
Thu 2/267:37 am
ORD
- DSM
Nonstop1h 24m
American Airlines
Deal found 1/27![American Airlines logo]()
$171
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:37 pm
DSM
- ORD
Nonstop1h 31m
American Airlines
Sun 4/510:26 pm
ORD
- DSM
Nonstop1h 22m
American Airlines
Deal found 1/27![American Airlines logo]()
$172
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:10 am
DSM
- MDW
1 stop3h 20m
Southwest
Mon 3/169:50 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Deal found 1/27![Southwest logo]()
$174
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/248:35 am
DSM
- MDW
1 stop8h 10m
Southwest
Tue 3/36:10 am
MDW
- DSM
1 stop5h 15m
Southwest
Deal found 1/27![Southwest logo]()
$177
Find flight deals from Des Moines to Illinois
Keep the following information in mind while searching for Des Moines to Illinois flight deals. Data was last updated January 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $97 (Southwest) |
One-way from | $59 (Southwest) |
Popular in | January |
Cheapest in | September |
Average price | $291 |
Good round-trip deal | $386 or less |
Good one-way deal | $188 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Des Moines to Illinois that are best for you.
Fly from
Des Moines
Fly to
Illinois
Route
Depart
Return
Price
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 2/24
3:20 pm-4:35 pm
Nonstop1h 15m
Lambert-St Louis
Tue 3/3
8:00 pm-9:10 pm
Nonstop1h 10m
$97
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 3/10
1:55 pm-9:35 pm
1 stop7h 40m
Lambert-St Louis
Wed 3/11
4:00 pm-10:05 pm
1 stop6h 05m
$117
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 2/24
10:57 am-8:43 pm
2 stops9h 46m
Lambert-St Louis
Tue 3/3
3:40 pm-9:20 pm
1 stop5h 40m
$162
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Wed 4/1
7:44 pm-9:19 pm
Nonstop1h 35m
Chicago O'Hare Intl
Sat 4/4
7:25 am-8:49 am
Nonstop1h 24m
$164
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Wed 2/25
3:20 pm-7:05 pm
1 stop3h 45m
Chicago Midway
Tue 3/17
10:15 am-11:40 am
Nonstop1h 25m
$167
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Sat 2/28
8:00 am-9:36 am
Nonstop1h 36m
Chicago O'Hare Intl
Mon 3/9
8:10 pm-9:41 pm
Nonstop1h 31m
$171
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Thu 2/26
5:00 am-6:29 am
Nonstop1h 29m
Chicago O'Hare Intl
Thu 2/26
11:40 am-1:05 pm
Nonstop1h 25m
$171
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Thu 5/7
11:40 am-1:12 pm
Nonstop1h 32m
Chicago O'Hare Intl
Mon 5/11
12:57 pm-2:24 pm
Nonstop1h 27m
$171
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Mon 2/23
5:00 am-6:29 am
Nonstop1h 29m
Chicago O'Hare Intl
Thu 2/26
7:37 am-9:01 am
Nonstop1h 24m
$171
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Thu 5/7
4:20 pm-5:40 pm
Nonstop1h 20m
Chicago Midway
Mon 5/11
9:45 pm-11:05 pm
Nonstop1h 20m
$171
Showing 1-10 of 60 results
Best time to book a flight from Des Moines to Illinois
Have a flexible travel schedule? Discover the best time to fly to Illinois from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Illinois
What is the cheapest month to book a flight from Des Moines to Illinois?
Currently, February is the cheapest month in which you can book a flight from Des Moines to Illinois (average of $148). Flying from Des Moines to Illinois in January is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to IL?
Find hourly flight availability from Des Moines to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 28, 2026.
One of the essential ways to save on airfare from Des Moines to Illinois is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the morning could potentially save you up to 31% on airfare.
What is the cheapest day to fly from Des Moines to Illinois?
Use this chart to determine the cheapest time to fly round-trip from Des Moines to Illinois. Price data was last updated on January 24, 2026.
Travelers seeking maximum savings on their Des Moines to Illinois flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Des Moines to Illinois
Explore weekly flight availability from Des Moines to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 28, 2026.
The most flights from DSM to USIL are scheduled on a Monday (34 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (19 on average).
Reviews of airlines servicing Illinois
Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated January 28, 2026.
Get a feel of what it's like to fly with Southwest, United Airlines, and American Airlines from Des Moines to Illinois by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Illinois
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Des Moines to Illinois
Discover the top 2 airlines that operate flights from Des Moines to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$148 | Average$246 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$254 | FlexibilityNo cancel fee | On-time69% |