HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Hilton Head Island

$224+ Cheap flights from Des Moines to Hilton Head Island (DSM - HHH)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — HHH
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Hilton Head Island with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Des Moines to Hilton Head Island

Cheapest flights from Des Moines to Hilton Head Island
Explore the most affordable flight options available from Des Moines to Hilton Head Island. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:40 amDSM - HHH
1 stop6h 07mAmerican Airlines
Thu 12/186:13 pmHHH - DSM
1 stop7h 24mAmerican Airlines
Deal found 10/27$373
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:00 amDSM - HHH
2 stops12h 33mAmerican Airlines
Fri 12/266:13 pmHHH - DSM
1 stop7h 24mAmerican Airlines
Deal found 10/29$405
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:44 amDSM - HHH
1 stop6h 13mAmerican Airlines
Sun 11/166:40 pmHHH - DSM
1 stop6h 41mAmerican Airlines
Deal found 10/28$598
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:57 pmDSM - HHH
2 stops18h 19mAmerican Airlines
Sat 1/36:13 pmHHH - DSM
1 stop7h 24mAmerican Airlines
Deal found 10/29$753

Cheap flight deals from Des Moines to Hilton Head Island

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Hilton Head Island (HHH). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$373
(American Airlines)

One-way from

$224
(American Airlines)

Popular in

April

Cheapest in

July

Average price

$338
Provider with most accurate pricing for Des Moines-Hilton Head Island flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Hilton Head Island flights.
Search Deals
From Des Moines to Hilton Head Island
Search Deals
One-way flight from Des Moines to Hilton Head Island
Search Deals
Highest demand for flights based on searches. 28% potential increase in price ($178 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Hilton Head Island that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Des Moines to Hilton Head Island that are best for you.

Fly from

Des Moines

Fly to

Hilton Head Island

Route

Depart

Return

Price

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Thu 12/11

6:40 am-1:47 pm

1 stop6h 07m

Hilton Head Island

Thu 12/18

6:13 pm-12:37 am

1 stop7h 24m

$373

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Wed 12/3

5:00 am-6:33 pm

2 stops12h 33m

Hilton Head Island

Fri 12/26

6:13 pm-12:37 am

1 stop7h 24m

$405

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Fri 11/28

6:39 am-2:19 pm

1 stop6h 40m

$224

Des MoinesHilton Head Island

DSM - HHH

DSMHHH

Des Moines

Fri 11/21

6:39 am-2:19 pm

1 stop6h 40m

$234

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Compare providers for flights from Des Moines to Hilton Head Island

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Hilton Head Island in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Hilton Head Island flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Hilton Head Island flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Hilton Head Island flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Hilton Head Island flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Hilton Head Island flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Hilton Head Island

Have a flexible travel schedule? Discover the best time to fly to Hilton Head Island from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Hilton Head Island

What is the cheapest month to book a flight from Des Moines to Hilton Head Island?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Hilton Head Island (average of $166). Flying from Des Moines to Hilton Head Island in February is currently the most expensive (average of $287). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Hilton Head Island

Get insights into the airlines that provide service to Hilton Head Island. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Hilton Head Island. Reviews last updated October 29, 2025.
Read through reviews of airlines operating flights from Des Moines to Hilton Head Island, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,030 reviews

Crew

8.0

Food

6.4

Boarding

7.5

Entertainment

6.9

Overall

7.2

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,030 reviews
American Airlines
7.2
Good
11,030 reviews

Crew

8.0

Food

6.4

Boarding

7.5

Entertainment

6.9

Overall

7.2

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Hilton Head Island. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Hilton Head Island?

    There are many flights that can get you from Des Moines to Hilton Head Island in 6h 07m. Fly via American Airlines to get the fastest option. There are 960 mi between Des Moines and Hilton Head Island.

  • What is the cheapest airline to fly from Des Moines to Hilton Head Island round-trip?

    Cheapflights users have booked flights from Des Moines to Hilton Head Island round-trip from $258. Users have found that American Airlines is 43% cheaper than the other options available to this destination.

  • Can I find deals for flights from Des Moines to Hilton Head Island that include hotel bookings?

    Yes. In addition to deals on Des Moines to Hilton Head Island flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Hilton Head Island?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Hilton Head Island.

  • Can I find deals for business class flights from Des Moines to Hilton Head Island?

    Yes. Cheapflights offers flight deals from Des Moines to Hilton Head Island by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Hilton Head Island?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Hilton Head Island (average of $166). Flying from Des Moines to Hilton Head Island in February is currently the most expensive (average of $287). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Hilton Head Island?

Book flights to Hilton Head Island if you plan to visit one of these locations
Beaufort
Bluffton

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Hilton Head Island

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Charlotte flights
Des Moines to Charleston flights
Omaha to Charleston flights
Moline to Charlotte flights
Cedar Rapids to Charlotte flights
Des Moines to Charlotte flights
Cedar Rapids to Greenville flights
Omaha to Savannah flights
Cedar Rapids to Charleston flights
Des Moines to Columbia flights
Cedar Rapids to Savannah flights
Cedar Rapids to Columbia flights
Moline to Columbia flights
Des Moines to Savannah flights
Moline to Savannah flights
Moline to Charleston flights
Des Moines to Greenville flights
Des Moines to Myrtle Beach flights
Moline to Greenville flights
Omaha to Columbia flights
Moline to Myrtle Beach flights
Cedar Rapids to Myrtle Beach flights
Omaha to Myrtle Beach flights
La Crosse to Charleston flights
Omaha to Greenville flights
Cedar Rapids to Hilton Head Island flights
Moline to Augusta flights
Moline to Hilton Head Island flights
Omaha to Hilton Head Island flights
Waterloo to Charlotte flights
Sioux City to Charleston flights
Sioux City to Columbia flights
Sioux City to Charlotte flights
La Crosse to Greenville flights
Waterloo to Greenville flights
La Crosse to Savannah flights
La Crosse to Charlotte flights
Moline to Florence flights
Dubuque to Savannah flights
Omaha to Florence flights
Dubuque to Myrtle Beach flights
Dubuque to Greenville flights
Dubuque to Charlotte flights
Cedar Rapids to Florence flights
Waterloo to Myrtle Beach flights

Top airline flying from Des Moines to Hilton Head Island

Discover the top airline that operate flights from Des Moines to Hilton Head Island. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$352FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.