HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Gulfport

$234+ Cheap flights from Des Moines to Gulfport (DSM - GPT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GPT
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Gulfport with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Gulfport

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Gulfport (GPT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(American Airlines)

One-way from

$234
(American Airlines)

Popular in

February

Cheapest in

August

Average price

$370
Provider with most accurate pricing for Des Moines-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Gulfport Biloxi Regional flights.
Search Deals
From Des Moines to Gulfport Biloxi Regional
Search Deals
One-way flight from Des Moines to Gulfport Biloxi Regional
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($79 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Des Moines to Gulfport

Cheapest flights from Des Moines to Gulfport
Explore the most affordable flight options available from Des Moines to Gulfport. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:05 pmDSM - GPT
1 stop5h 28mAmerican Airlines
Sun 12/74:38 pmGPT - DSM
1 stop7h 47mAmerican Airlines
Deal found 10/26$249
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:17 amDSM - GPT
2 stops7h 51mDelta
Sun 12/76:00 amGPT - DSM
1 stop4h 38mDelta
Deal found 10/26$254
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/235:26 pmDSM - GPT
1 stop5h 37mAmerican Airlines
Fri 11/285:20 amGPT - DSM
1 stop5h 20mAmerican Airlines
Deal found 10/25$326
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/143:18 pmDSM - GPT
1 stop7h 26mAmerican Airlines
Sun 11/165:20 amGPT - DSM
1 stop5h 20mAmerican Airlines
Deal found 10/27$344
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/512:15 pmDSM - GPT
2 stops10h 18mAmerican Airlines
Mon 12/87:00 amGPT - DSM
2 stops10h 57mAmerican Airlines
Deal found 10/26$465
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/52:52 pmDSM - GPT
1 stop6h 44mUnited Airlines
Fri 11/75:15 pmGPT - DSM
1 stop20h 56mUnited Airlines
Deal found 10/27$533

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Gulfport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Des Moines to Gulfport that are best for you.

Fly from

Des Moines

Fly to

Gulfport

Route

Depart

Return

Price

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Fri 12/5

5:04 pm-10:33 pm

1 stop5h 29m

Gulfport Biloxi Regional

Mon 12/8

7:00 am-2:33 pm

1 stop7h 33m

$249

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Wed 12/3

5:05 pm-10:33 pm

1 stop5h 28m

Gulfport Biloxi Regional

Sun 12/7

4:38 pm-12:25 am

1 stop7h 47m

$249

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Fri 11/14

3:18 pm-10:44 pm

1 stop7h 26m

Gulfport Biloxi Regional

Sun 11/16

5:20 am-10:40 am

1 stop5h 20m

$344

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Sun 11/23

1:06 pm-11:57 pm

2 stops10h 51m

Gulfport Biloxi Regional

Fri 11/28

7:15 am-6:26 pm

2 stops11h 11m

$550

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Thu 11/27

6:05 am-1:20 pm

1 stop7h 15m

Gulfport Biloxi Regional

Sun 11/30

9:51 pm-10:20 pm

1 stop24h 29m

$553

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Sun 11/23

6:05 am-11:17 am

1 stop5h 12m

Gulfport Biloxi Regional

Sun 11/30

9:51 pm-10:20 pm

1 stop24h 29m

$553

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Tue 11/25

6:05 am-11:17 am

1 stop5h 12m

Gulfport Biloxi Regional

Sun 11/30

9:51 pm-10:20 pm

1 stop24h 29m

$592

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Fri 12/5

5:00 am-12:25 pm

1 stop7h 25m

$234

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Fri 12/5

6:17 am-2:08 pm

2 stops7h 51m

$239

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Fri 12/5

8:00 am-1:20 pm

3 stops29h 20m

$412

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 11 results
1
2

Compare providers for flights from Des Moines to Gulfport

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Gulfport in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Gulfport flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Gulfport flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Gulfport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Gulfport flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Gulfport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Gulfport

Have a flexible travel schedule? Discover the best time to fly to Gulfport from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Gulfport

What is the cheapest month to book a flight from Des Moines to Gulfport?

Currently, October is the cheapest month in which you can book a flight from Des Moines to Gulfport (average of $126). Flying from Des Moines to Gulfport in June is currently the most expensive (average of $331). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Gulfport?

Reviews of airlines servicing Gulfport

Get insights into the airlines that provide service to Gulfport. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Gulfport. Reviews last updated October 28, 2025.
Peruse reviews from past customers who have flown with American Airlines from Des Moines to Gulfport to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,032 reviews

Crew

8.0

Boarding

7.5

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,032 reviews
American Airlines
7.2
Good
11,032 reviews

Crew

8.0

Boarding

7.5

Food

6.4

Comfort

7.2

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Gulfport. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Gulfport?

    American Airlines can get you from Des Moines to Gulfport in just under 5h 29m. Your travel time can differ by up to . There are 810 mi between Des Moines and Gulfport.

  • What is the cheapest airline to fly from Des Moines to Gulfport round-trip?

    Flying on American Airlines is currently your cheapest option to Gulfport, with prices starting at $248. American Airlines is currently priced 31% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Des Moines to Gulfport one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $234. Delta flights start at $239 while deals on United Airlines start at $412 one-way.

  • Can I find deals for flights from Des Moines to Gulfport that include hotel bookings?

    Yes. In addition to deals on Des Moines to Gulfport flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Gulfport?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Gulfport.

  • Can I find deals for business class flights from Des Moines to Gulfport?

    Yes. Cheapflights offers flight deals from Des Moines to Gulfport by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Gulfport?

    Currently, October is the cheapest month in which you can book a flight from Des Moines to Gulfport (average of $126). Flying from Des Moines to Gulfport in June is currently the most expensive (average of $331). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Gulfport?

Book flights to Gulfport if you plan to visit one of these locations
Ocean Springs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Gulfport

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Mobile flights
Omaha to Gulfport flights
Omaha to Mobile flights
Cedar Rapids to Baton Rouge flights
Des Moines to Memphis flights
Omaha to Alexandria flights
Moline to Mobile flights
Des Moines to Jackson flights
Omaha to Memphis flights
Cedar Rapids to Gulfport flights
Cedar Rapids to Mobile flights
Moline to Memphis flights
Omaha to Baton Rouge flights
Des Moines to Alexandria flights
Des Moines to Baton Rouge flights
Moline to Baton Rouge flights
Moline to Alexandria flights
Cedar Rapids to Alexandria flights
Omaha to Laurel flights
La Crosse to Gulfport flights
La Crosse to Memphis flights
Omaha to Columbus flights
La Crosse to Baton Rouge flights
Dubuque to Mobile flights
Cedar Rapids to Columbus flights

Top airline flying from Des Moines to Gulfport

Discover the top airline that operate flights from Des Moines to Gulfport. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$318FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.