HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Gulfport

$231+ Cheap flights from Des Moines to Gulfport (DSM - GPT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GPT
Mar 21 — Mar 281
Sat 3/21
Sat 3/28
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Gulfport with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Gulfport

Cheapest flights from Des Moines to Gulfport
Explore the most affordable flight options available from Des Moines to Gulfport. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 19, 2026.

This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:25 am
DSM
-
GPT
1 stop6h 12m
American Airlines
Sat 9/1912:40 pm
GPT
-
DSM
1 stop4h 59m
American Airlines
Deal found 2/16$269
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:20 am
DSM
-
GPT
2 stops7h 13m
Delta
Sat 9/196:00 pm
GPT
-
DSM
1 stop4h 26m
Delta
Deal found 2/16$274
This Delta deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:15 pm
DSM
-
GPT
1 stop4h 39m
Delta
Tue 3/105:57 pm
GPT
-
DSM
1 stop4h 41m
Delta
Deal found 2/15$304
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/231:48 pm
DSM
-
GPT
2 stops10h 09m
American Airlines
Tue 3/105:00 am
GPT
-
DSM
1 stop5h 34m
American Airlines
Deal found 2/15$309
This Delta deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:15 pm
DSM
-
GPT
1 stop4h 39m
Delta
Tue 3/105:57 pm
GPT
-
DSM
1 stop4h 41m
Delta
Deal found 2/15$319
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:00 am
DSM
-
GPT
1 stop5h 26m
United Airlines
Wed 9/22:00 pm
GPT
-
DSM
2 stops10h 30m
United Airlines
Deal found 2/17$344
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:15 am
DSM
-
GPT
1 stop6h 10m
United Airlines
Mon 3/94:55 pm
GPT
-
DSM
1 stop5h 49m
United Airlines
Deal found 2/18$378
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/241:48 pm
DSM
-
GPT
2 stops10h 01m
American Airlines
Tue 3/106:31 am
GPT
-
DSM
1 stop6h 36m
American Airlines
Deal found 2/15$392

Find flight deals from Des Moines to Gulfport

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Gulfport (GPT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$378
(United Airlines)

One-way from

$231

Popular in

November

Cheapest in

August

Average price

$353
Provider with most accurate pricing for Des Moines-Gulfport Biloxi Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Gulfport Biloxi Regional flights.
Search Deals
From Des Moines to Gulfport Biloxi Regional
Search Deals
One-way flight from Des Moines to Gulfport Biloxi Regional
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Gulfport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 19, 2026.
Use the filters below to find and compare flights from Des Moines to Gulfport that are best for you.

Fly from

Des Moines

Fly to

Gulfport

Route

Depart

Return

Price

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Thu 3/5

7:15 am-1:25 pm

1 stop6h 10m

Gulfport Biloxi Regional

Mon 3/9

4:55 pm-10:44 pm

1 stop5h 49m

$378

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Thu 3/5

5:00 am-12:34 pm

2 stops7h 34m

Gulfport Biloxi Regional

Mon 3/9

4:29 pm-9:59 pm

1 stop5h 30m

$442

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Fri 4/3

5:20 pm-10:15 pm

1 stop4h 55m

Gulfport Biloxi Regional

Mon 4/6

5:57 pm-10:38 pm

1 stop4h 41m

$453

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Wed 6/3

3:01 pm-7:51 pm

1 stop4h 50m

Gulfport Biloxi Regional

Sun 6/7

2:00 pm-12:33 am

2 stops10h 33m

$506

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Thu 6/4

5:00 am-1:25 pm

2 stops8h 25m

Gulfport Biloxi Regional

Sun 6/7

2:00 pm-12:33 am

2 stops10h 33m

$546

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Mon 3/2

5:15 pm-9:54 pm

1 stop4h 39m

Gulfport Biloxi Regional

Fri 3/6

2:54 pm-10:28 pm

1 stop7h 34m

$547

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Mon 3/2

5:00 am-12:34 pm

2 stops7h 34m

Gulfport Biloxi Regional

Fri 3/6

5:00 am-10:34 am

1 stop5h 34m

$552

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Wed 4/22

8:20 am-1:21 pm

1 stop5h 01m

Gulfport Biloxi Regional

Mon 4/27

5:15 pm-10:43 pm

1 stop5h 28m

$558

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Wed 4/22

8:20 am-1:21 pm

1 stop5h 01m

$231

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Mon 3/16

6:49 pm-4:06 pm

2 stops21h 17m

$334

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/16

Showing 1-10 of 14 results
1
2

Compare providers for flights from Des Moines to Gulfport

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Gulfport in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Gulfport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Gulfport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Gulfport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Gulfport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Gulfport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Gulfport

Have a flexible travel schedule? Discover the best time to fly to Gulfport from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Gulfport

What is the cheapest month to book a flight from Des Moines to Gulfport?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Gulfport (average of $100). Flying from Des Moines to Gulfport in May is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Gulfport

Get insights into the airlines that provide service to Gulfport. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Gulfport. Reviews last updated February 19, 2026.
Peruse reviews from past customers who have flown with American Airlines from Des Moines to Gulfport to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,313 reviews

Boarding

7.5

Food

6.4

Comfort

7.2

Crew

8.0

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,313 reviews
American Airlines
7.2
Good
11,313 reviews

Boarding

7.5

Food

6.4

Comfort

7.2

Crew

8.0

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Gulfport. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Gulfport?

    United Airlines, American Airlines, and Delta can get you from Des Moines to Gulfport in just under 4h 55m. Your travel time can differ by up to 2h 39m. There are 810 mi between Des Moines and Gulfport. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Des Moines to Gulfport round-trip?

    Flying on American Airlines is currently your cheapest option to Gulfport, with prices starting at $248. American Airlines is currently priced 25% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Gulfport that include hotel bookings?

    Yes. In addition to deals on Des Moines to Gulfport flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Gulfport?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Gulfport.

  • Can I find deals for business class flights from Des Moines to Gulfport?

    Yes. Cheapflights offers flight deals from Des Moines to Gulfport by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Gulfport?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Gulfport (average of $100). Flying from Des Moines to Gulfport in May is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Gulfport?

Book flights to Gulfport if you plan to visit one of these locations
Ocean Springs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Des Moines to Gulfport

Discover the top airline that operate flights from Des Moines to Gulfport. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$308FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights