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$279+ Cheap flights from Des Moines to Mobile (DSM - MOB)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MOB
May 24 — May 311
Sun 5/24
Sun 5/31
1 adult, Economy
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Cheap flight deals from Des Moines to Mobile

Cheapest flights from Des Moines to Mobile
Explore the most affordable flight options available from Des Moines to Mobile. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.

This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:04 am
DSM
-
MOB
1 stop7h 13m
Delta
Tue 11/1712:10 pm
MOB
-
DSM
1 stop5h 32m
Delta
Deal found 4/20$311
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:24 pm
DSM
-
MOB
2 stops10h 32m
American Airlines
Tue 11/175:08 am
MOB
-
DSM
1 stop5h 37m
American Airlines
Deal found 4/20$316
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:02 pm
DSM
-
MOB
1 stop4h 57m
American Airlines
Tue 6/94:29 pm
MOB
-
DSM
1 stop7h 41m
American Airlines
Deal found 4/19$320
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:38 pm
DSM
-
MOB
1 stop4h 47m
Delta
Tue 8/116:00 am
MOB
-
DSM
1 stop4h 14m
Delta
Deal found 4/22$329
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:20 pm
DSM
-
MOB
1 stop7h 39m
American Airlines
Sun 5/105:22 am
MOB
-
DSM
1 stop6h 04m
American Airlines
Deal found 4/21$339
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:41 pm
DSM
-
MOB
1 stop4h 47m
Delta
Tue 5/194:41 pm
MOB
-
DSM
1 stop5h 51m
Delta
Deal found 4/22$364
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:02 pm
DSM
-
MOB
1 stop4h 57m
American Airlines
Mon 6/154:29 pm
MOB
-
DSM
1 stop7h 41m
American Airlines
Deal found 4/21$384
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:20 am
DSM
-
MOB
1 stop5h 37m
United Airlines
Sat 5/305:13 pm
MOB
-
DSM
1 stop5h 22m
United Airlines
Deal found 4/19$391
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/64:00 pm
DSM
-
MOB
1 stop4h 13m
Delta
Sun 6/76:05 am
MOB
-
DSM
1 stop4h 38m
Delta
Deal found 4/22$399
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:50 am
DSM
-
MOB
2 stops10h 29m
United Airlines
Sat 5/305:13 pm
MOB
-
DSM
1 stop5h 22m
United Airlines
Deal found 4/20$405

Find flight deals from Des Moines to Mobile

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Mobile (MOB). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$320
(American Airlines)

One-way from

$279
(Delta)

Popular in

December

Cheapest in

October

Average price

$268
Provider with most accurate pricing for Des Moines-Mobile flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Mobile flights.
Search Deals
From Des Moines to Mobile
Search Deals
One-way flight from Des Moines to Mobile
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($37 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Mobile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Des Moines to Mobile that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Fri 6/5

7:02 pm-11:59 pm

1 stop4h 57m

Mobile

Tue 6/9

4:29 pm-12:10 am

1 stop7h 41m

$320
Quickest round-trip

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Wed 5/13

6:41 pm-11:28 pm

1 stop4h 47m

Mobile

Tue 5/19

4:41 pm-10:32 pm

1 stop5h 51m

$364

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Wed 5/27

6:20 am-11:57 am

1 stop5h 37m

Mobile

Sat 5/30

5:13 pm-10:35 pm

1 stop5h 22m

$391

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Wed 5/6

1:35 pm-9:59 pm

2 stops8h 24m

Mobile

Sun 5/10

7:00 am-4:15 pm

2 stops9h 15m

$437

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sat 8/29

5:00 am-6:17 pm

2 stops13h 17m

Mobile

Wed 9/2

9:30 am-2:17 pm

1 stop4h 47m

$450

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sun 5/24

5:50 am-4:19 pm

2 stops10h 29m

Mobile

Sat 5/30

11:00 am-8:30 pm

2 stops9h 30m

$464
Cheapest one-way

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 6/30

5:25 am-11:57 am

1 stop6h 32m

$279

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Thu 7/2

7:04 am-12:17 pm

1 stop5h 13m

$279

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 6/30

7:00 am-4:04 pm

2 stops9h 04m

$284
Quickest one-way

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Fri 6/5

6:41 pm-11:28 pm

1 stop4h 47m

$358

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/20

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Compare providers for flights from Des Moines to Mobile

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Mobile in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Mobile flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Mobile flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Mobile flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Mobile flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Mobile flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Mobile

Have a flexible travel schedule? Discover the best time to fly to Mobile from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mobile

How much does it cost to fly round-trip from Des Moines to Mobile?

Reviews of airlines servicing Mobile

Get insights into the airlines that provide service to Mobile. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mobile. Reviews last updated April 24, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Des Moines to Mobile. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,450 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,450 reviews
Delta
7.9
Good
8,450 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,643 reviews
Delta
7.9
Good
8,450 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,666 reviews
Delta
7.9
Good
8,450 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mobile. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Mobile?

    American Airlines, Delta, and United Airlines can get you from Des Moines to Mobile in just under 4h 47m. Your travel time can differ by up to 50m. Airlines will cover a distance of 807 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Mobile round-trip?

    American Airlines, at $248, was found to be the cheapest airline from Des Moines to Mobile.Alternate airlines to your destination round-trip include Delta and United Airlines. These flights start at 42% lower than the current average price 3 months from now.

  • Can I find deals for flights from Des Moines to Mobile that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mobile flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mobile?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mobile.

  • Can I find deals for business class flights from Des Moines to Mobile?

    Yes. Cheapflights offers flight deals from Des Moines to Mobile by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Mobile?

Book flights to Mobile if you plan to visit one of these locations
Pascagoula
Moss Point

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Des Moines to Mobile

Discover the top 3 airlines that operate flights from Des Moines to Mobile. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$319FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$438FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$258Average$328FlexibilityNo cancel feeOn-time69%

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