HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

Cheap flights from Knoxville to Greenville (TYS - GSP)

TYS — GSP
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Best time to book a flight from Knoxville to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Greenville

What is the cheapest month to book a flight from Knoxville to Greenville?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Greenville (average of $321). Flying from Knoxville to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 16, 2025.
Read reviews from past customers who have flown American Airlines from Knoxville to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Overall

7.2

Entertainment

6.9

Food

6.4

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Overall

7.2

Entertainment

6.9

Food

6.4

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Knoxville to Greenville round-trip?

    American Airlines, at $296, was found to be the cheapest airline from Knoxville to Greenville..

  • Can I find deals for flights from Knoxville to Greenville that include hotel bookings?

    Yes. In addition to deals on Knoxville to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Greenville.

  • Can I find deals for business class flights from Knoxville to Greenville?

    Yes. Cheapflights offers flight deals from Knoxville to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Greenville (average of $321). Flying from Knoxville to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Savannah flights
Nashville to Charleston flights
Nashville to Charlotte flights
Memphis to Charlotte flights
Memphis to Augusta flights
Memphis to Savannah flights
Knoxville to Myrtle Beach flights
Memphis to Greenville flights
Nashville to Columbia flights
Memphis to Charleston flights
Chattanooga to Charlotte flights
Nashville to Myrtle Beach flights
Knoxville to Charlotte flights
Memphis to Columbia flights
Chattanooga to Charleston flights
Knoxville to Savannah flights
Nashville to Greenville flights
Memphis to Myrtle Beach flights
Knoxville to Charleston flights
Nashville to Augusta flights
Chattanooga to Savannah flights
Chattanooga to Columbia flights
Chattanooga to Myrtle Beach flights
Knoxville to Hilton Head Island flights
Nashville to Hilton Head Island flights
Blountville to Charlotte flights
Blountville to Myrtle Beach flights
Memphis to Hilton Head Island flights
Knoxville to Columbia flights
Memphis to Florence flights
Nashville to Florence flights
Chattanooga to Hilton Head Island flights

Top airline flying from Knoxville to Greenville

Discover the top airline that operate flights from Knoxville to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$296Average$478FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.