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$166+ Cheap flights from Des Moines to Greensboro (DSM - GSO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GSO
Oct 29 — Nov 51
Wed 10/29
Wed 11/5
1 adult, Economy
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Cheap flight deals from Des Moines to Greensboro

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Greensboro (GSO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$249
(Delta)

One-way from

$166
(Delta)

Popular in

September

Cheapest in

June

Average price

$457
Provider with most accurate pricing for Des Moines-Greensboro/H. Point flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Greensboro/H. Point flights.
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From Des Moines to Greensboro/H. Point
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One-way flight from Des Moines to Greensboro/H. Point
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Highest demand for flights based on searches. 9% potential increase in price ($33 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Greensboro

Cheapest flights from Des Moines to Greensboro
Explore the most affordable flight options available from Des Moines to Greensboro. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2025.

This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:15 pmDSM - GSO
1 stop7h 15mDelta
Tue 1/132:11 pmGSO - DSM
1 stop6h 52mDelta
Deal found 9/27$249
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/185:15 pmDSM - GSO
1 stop5h 41mDelta
Thu 10/236:17 amGSO - DSM
1 stop4h 03mDelta
Deal found 9/29$254
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/142:13 pmDSM - GSO
1 stop5h 57mDelta
Sat 10/186:00 amGSO - DSM
1 stop5h 05mDelta
Deal found 9/29$259
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/143:25 pmDSM - GSO
1 stop4h 38mUnited Airlines
Sat 10/186:15 amGSO - DSM
2 stops9h 08mUnited Airlines
Deal found 9/29$264
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/183:48 pmDSM - GSO
1 stop5h 59mAmerican Airlines
Mon 10/205:40 pmGSO - DSM
1 stop6h 16mAmerican Airlines
Deal found 9/27$279
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:15 pmDSM - GSO
1 stop7h 15mDelta
Sat 1/176:55 amGSO - DSM
1 stop4h 28mDelta
Deal found 9/27$294
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/231:18 pmDSM - GSO
1 stop7h 04mAmerican Airlines
Mon 1/126:17 amGSO - DSM
1 stop6h 54mAmerican Airlines
Deal found 9/28$330
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/188:00 amDSM - GSO
2 stops9h 51mUnited Airlines
Thu 10/236:15 amGSO - DSM
2 stops7h 04mUnited Airlines
Deal found 9/29$334

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Greensboro that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 29, 2025.
Use the filters below to find and compare flights from Des Moines to Greensboro that are best for you.

Fly from

Des Moines

Fly to

Greensboro

Route

Depart

Return

Price

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Tue 3/24

5:25 pm-11:00 pm

1 stop4h 35m

Greensboro/H. Point

Sat 3/28

6:55 am-10:23 am

1 stop4h 28m

$294

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Sat 10/18

6:00 am-2:18 pm

2 stops7h 18m

Greensboro/H. Point

Mon 10/20

5:40 pm-10:56 pm

1 stop6h 16m

$314

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Tue 12/23

1:18 pm-9:22 pm

1 stop7h 04m

Greensboro/H. Point

Mon 1/12

6:17 am-12:11 pm

1 stop6h 54m

$330

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Tue 3/24

11:30 am-10:14 pm

2 stops9h 44m

Greensboro/H. Point

Sat 3/28

5:34 pm-9:36 pm

1 stop5h 02m

$335

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Tue 12/23

1:18 pm-9:22 pm

1 stop7h 04m

Greensboro/H. Point

Thu 1/15

11:13 am-7:18 pm

2 stops9h 05m

$335

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Wed 12/24

1:15 pm-9:30 pm

1 stop7h 15m

Greensboro/H. Point

Fri 1/16

5:25 am-10:23 am

1 stop5h 58m

$341

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Thu 12/18

5:43 pm-11:13 pm

1 stop4h 30m

Greensboro/H. Point

Mon 1/12

2:11 pm-8:03 pm

1 stop6h 52m

$341

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Thu 12/18

5:34 am-11:25 am

1 stop4h 51m

Greensboro/H. Point

Thu 1/15

2:11 pm-8:03 pm

1 stop6h 52m

$341

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Thu 12/18

5:34 am-11:25 am

1 stop4h 51m

Greensboro/H. Point

Wed 1/14

4:30 pm-8:53 pm

1 stop5h 23m

$341

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Wed 10/29

2:13 pm-9:46 pm

1 stop6h 33m

$166

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/27

Showing 1-10 of 17 results
1
2

Compare providers for flights from Des Moines to Greensboro

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Greensboro in September.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Greensboro flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Greensboro flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Greensboro flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Greensboro flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Greensboro flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Greensboro

Have a flexible travel schedule? Discover the best time to fly to Greensboro from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Greensboro

What is the cheapest month to book a flight from Des Moines to Greensboro?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Greensboro (average of $306). Flying from Des Moines to Greensboro in October is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greensboro

Get insights into the airlines that provide service to Greensboro. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greensboro. Reviews last updated September 29, 2025.
See what other customers who have flown with Delta and American Airlines from Des Moines to Greensboro have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,964 reviews

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,964 reviews
Delta
8.0
Very good
7,964 reviews

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,964 reviews

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Greensboro. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Greensboro?

    Departing from Des Moines to Greensboro will take you 4h 35m. The distance between Des Moines and Greensboro is about 827 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Greensboro round-trip?

    According to our current data, American Airlines ($248), and Delta ($248) offers the cheapest pricing from Des Moines to Greensboro. American Airlines is currently priced 20% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Greensboro that include hotel bookings?

    Yes. In addition to deals on Des Moines to Greensboro flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Greensboro?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Greensboro.

  • Can I find deals for business class flights from Des Moines to Greensboro?

    Yes. Cheapflights offers flight deals from Des Moines to Greensboro by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Greensboro?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Greensboro (average of $306). Flying from Des Moines to Greensboro in October is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greensboro?

Book flights to Greensboro if you plan to visit one of these locations
Kernersville

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Top 2 airlines flying from Des Moines to Greensboro

Discover the top 2 airlines that operate flights from Des Moines to Greensboro. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$283FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$283FlexibilityNo cancel feeOn-timeN/A

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