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Greensboro

$227+ Cheap flights from Des Moines to Greensboro (DSM - GSO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GSO
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Des Moines to Greensboro

Cheapest flights from Des Moines to Greensboro
Explore the most affordable flight options available from Des Moines to Greensboro. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/285:40 amDSM - GSO
1 stop7h 00mDelta
Tue 12/26:00 amGSO - DSM
1 stop4h 40mDelta
Deal found 11/12$279
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/281:05 pmDSM - GSO
1 stop6h 40mUnited Airlines
Tue 12/26:00 amGSO - DSM
2 stops9h 20mUnited Airlines
Deal found 11/12$284
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/278:58 amDSM - GSO
1 stop7h 06mAmerican Airlines
Mon 12/16:49 pmGSO - DSM
1 stop6h 06mAmerican Airlines
Deal found 11/12$295
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:35 amDSM - GSO
1 stop7h 05mDelta
Sun 11/2310:06 amGSO - DSM
1 stop4h 26mDelta
Deal found 11/11$339
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/213:31 pmDSM - GSO
1 stop6h 06mAmerican Airlines
Sun 11/236:46 amGSO - DSM
2 stops7h 30mAmerican Airlines
Deal found 11/11$344
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/141:35 pmDSM - GSO
1 stop8h 17mUnited Airlines
Wed 11/198:09 amGSO - DSM
1 stop9h 03mUnited Airlines
Deal found 11/12$354
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/213:38 pmDSM - GSO
1 stop6h 21mAmerican Airlines
Thu 1/155:43 pmGSO - DSM
1 stop6h 40mAmerican Airlines
Deal found 11/12$368
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:32 pmDSM - GSO
1 stop4h 21mDelta
Sun 11/166:00 amGSO - DSM
1 stop4h 41mDelta
Deal found 11/12$369

Cheap flight deals from Des Moines to Greensboro

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Greensboro (GSO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(American Airlines)

One-way from

$227
(Delta)

Popular in

March

Cheapest in

June

Average price

$278
Provider with most accurate pricing for Des Moines-Greensboro/H. Point flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Greensboro/H. Point flights.
Search Deals
From Des Moines to Greensboro/H. Point
Search Deals
One-way flight from Des Moines to Greensboro/H. Point
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($37 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Greensboro that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Des Moines to Greensboro that are best for you.

Fly from

Des Moines

Fly to

Greensboro

Route

Depart

Return

Price

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Fri 1/9

7:39 am-3:28 pm

1 stop6h 49m

Greensboro/H. Point

Mon 1/12

7:41 pm-11:08 pm

1 stop4h 27m

$249

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Fri 1/9

1:35 pm-10:59 pm

1 stop8h 24m

Greensboro/H. Point

Mon 1/12

8:00 am-2:33 pm

1 stop7h 33m

$249

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Fri 11/28

5:40 am-1:40 pm

1 stop7h 00m

Greensboro/H. Point

Tue 12/2

6:00 am-9:40 am

1 stop4h 40m

$279

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Thu 12/18

5:34 am-11:25 am

1 stop4h 51m

Greensboro/H. Point

Mon 12/22

6:00 am-10:38 am

1 stop5h 38m

$284

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Thu 11/27

8:58 am-9:58 pm

2 stops12h 00m

Greensboro/H. Point

Mon 12/1

6:49 pm-11:55 pm

1 stop6h 06m

$300

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Fri 11/21

5:35 am-1:40 pm

1 stop7h 05m

Greensboro/H. Point

Sun 11/23

10:06 am-1:32 pm

1 stop4h 26m

$339

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Fri 11/21

3:31 pm-10:37 pm

1 stop6h 06m

Greensboro/H. Point

Sun 11/23

6:46 am-1:16 pm

2 stops7h 30m

$344

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Sun 12/21

3:38 pm-10:59 pm

1 stop6h 21m

Greensboro/H. Point

Thu 1/15

5:43 pm-11:23 pm

1 stop6h 40m

$368

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Mon 11/24

5:35 am-1:40 pm

1 stop7h 05m

$227

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Mon 11/24

1:56 pm-2:53 pm

3 stops47h 57m

$238

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 14 results
1
2

Compare providers for flights from Des Moines to Greensboro

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Greensboro in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Greensboro flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Greensboro flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Greensboro flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Greensboro flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Greensboro flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Greensboro

Have a flexible travel schedule? Discover the best time to fly to Greensboro from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Greensboro

What is the cheapest month to book a flight from Des Moines to Greensboro?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Greensboro (average of $146). Flying from Des Moines to Greensboro in February is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greensboro

Get insights into the airlines that provide service to Greensboro. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greensboro. Reviews last updated November 13, 2025.
See what other customers who have flown with Delta and American Airlines from Des Moines to Greensboro have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Greensboro. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Greensboro?

    Departing from Des Moines to Greensboro will take you 6h 49m. The distance between Des Moines and Greensboro is about 827 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Greensboro round-trip?

    According to our current data, American Airlines ($248), and Delta ($248) offers the cheapest pricing from Des Moines to Greensboro. American Airlines is currently priced 18% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Greensboro that include hotel bookings?

    Yes. In addition to deals on Des Moines to Greensboro flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Greensboro?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Greensboro.

  • Can I find deals for business class flights from Des Moines to Greensboro?

    Yes. Cheapflights offers flight deals from Des Moines to Greensboro by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Greensboro?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Greensboro (average of $146). Flying from Des Moines to Greensboro in February is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greensboro?

Book flights to Greensboro if you plan to visit one of these locations
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Top 2 airlines flying from Des Moines to Greensboro

Discover the top 2 airlines that operate flights from Des Moines to Greensboro. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$293FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$283FlexibilityNo cancel feeOn-timeN/A

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