HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Gainesville

$308+ Cheap flights from St. Louis to Gainesville (STL - GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/20. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GNV
Feb 5 — Feb 121
Thu 2/5
Thu 2/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St. Louis to Gainesville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from St. Louis to Gainesville

Cheapest flights from St. Louis to Gainesville
Explore the most affordable flight options available from St. Louis to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 6, 2026.

This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/274:13 pmSTL - GNV
1 stop5h 47mAmerican Airlines
Tue 3/106:00 amGNV - STL
1 stop5h 32mAmerican Airlines
Deal found 1/5$367
This Delta deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:30 pmSTL - GNV
1 stop3h 53mDelta
Sat 6/610:20 amGNV - STL
1 stop6h 38mDelta
Deal found 1/3$382
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:35 amSTL - GNV
1 stop5h 10mAmerican Airlines
Mon 3/24:15 pmGNV - STL
1 stop8h 07mAmerican Airlines
Deal found 1/5$397
This Delta deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:20 amSTL - GNV
1 stop4h 03mDelta
Sun 6/77:05 pmGNV - STL
1 stop5h 33mDelta
Deal found 1/3$412
This Delta deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:51 amSTL - GNV
1 stop5h 32mDelta
Mon 6/84:59 pmGNV - STL
1 stop4h 50mDelta
Deal found 1/3$427
This American Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:06 amSTL - GNV
2 stops7h 37mAmerican Airlines
Mon 3/23:08 pmGNV - STL
1 stop5h 22mAmerican Airlines
Deal found 1/4$476
This American Airlines deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:26 amSTL - GNV
1 stop4h 55mAmerican Airlines
Sat 6/69:44 amGNV - STL
2 stops12h 17mAmerican Airlines
Deal found 1/3$487
This American Airlines deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:26 amSTL - GNV
1 stop4h 55mAmerican Airlines
Sat 6/69:44 amGNV - STL
2 stops12h 17mAmerican Airlines
Deal found 1/3$517

Find flight deals from St. Louis to Gainesville

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Gainesville (GNV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 6, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$367
(American Airlines)

One-way from

$308
(American Airlines)

Popular in

March

Cheapest in

June

Average price

$385
Provider with most accurate pricing for Lambert-St Louis-Gainesville Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Gainesville Regional flights.
Search Deals
From Lambert-St Louis to Gainesville Regional
Search Deals
One-way flight from Lambert-St Louis to Gainesville Regional
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
Use the filters below to find and compare flights from St. Louis to Gainesville that are best for you.

Fly from

St. Louis

Fly to

Gainesville

Route

Depart

Return

Price

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Sat 5/30

6:00 am-12:23 pm

1 stop5h 23m

Gainesville Regional

Sat 6/6

10:20 am-3:58 pm

1 stop6h 38m

$367

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Wed 3/18

4:13 pm-11:00 pm

1 stop5h 47m

Gainesville Regional

Mon 3/23

6:00 am-10:32 am

1 stop5h 32m

$367

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Fri 2/27

4:13 pm-11:00 pm

1 stop5h 47m

Gainesville Regional

Tue 3/10

6:00 am-10:32 am

1 stop5h 32m

$367

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Thu 5/28

1:30 pm-6:23 pm

1 stop3h 53m

Gainesville Regional

Sat 6/6

10:20 am-3:58 pm

1 stop6h 38m

$382

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Sat 5/30

6:00 am-12:23 pm

1 stop5h 23m

Gainesville Regional

Thu 6/4

7:05 pm-11:38 pm

1 stop5h 33m

$382

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Sun 5/31

7:20 am-12:23 pm

1 stop4h 03m

Gainesville Regional

Sat 6/6

10:20 am-3:58 pm

1 stop6h 38m

$382

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Mon 6/1

1:30 pm-6:23 pm

1 stop3h 53m

Gainesville Regional

Sat 6/6

10:20 am-3:58 pm

1 stop6h 38m

$382

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Thu 2/26

9:35 am-3:45 pm

1 stop5h 10m

Gainesville Regional

Mon 3/2

4:15 pm-11:22 pm

1 stop8h 07m

$397

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Thu 3/5

10:13 am-4:02 pm

1 stop4h 49m

Gainesville Regional

Mon 3/9

7:00 pm-11:58 pm

1 stop5h 58m

$397

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Thu 5/28

6:00 am-12:23 pm

1 stop5h 23m

Gainesville Regional

Thu 6/4

7:05 pm-11:38 pm

1 stop5h 33m

$397

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/4

Showing 1-10 of 14 results
1
2

Compare providers for flights from St. Louis to Gainesville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Gainesville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Gainesville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Gainesville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Gainesville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Gainesville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Gainesville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Gainesville

What is the cheapest month to book a flight from St. Louis to Gainesville?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Gainesville (average of $54). Flying from St. Louis to Gainesville in September is currently the most expensive (average of $118). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Gainesville

Get insights into the airlines that provide service to Gainesville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Gainesville. Reviews last updated January 6, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from St. Louis to Gainesville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,018 reviews

Entertainment

7.8

Boarding

8.1

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
Delta
7.9
Good
8,018 reviews
Delta
7.9
Good
8,018 reviews

Entertainment

7.8

Boarding

8.1

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
American Airlines
7.2
Good
11,084 reviews
Delta
7.9
Good
8,018 reviews

Entertainment

7.8

Boarding

8.1

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Gainesville?

    For as low as $367, Delta can have you in Gainesville from St. Louis in 5h 23m. Airlines will cover a distance of 777 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from St. Louis to Gainesville round-trip?

    Flying on Delta is currently your cheapest option to Gainesville, with prices starting at $248. Another option worth looking into is American Airlines, starting at $278 round trip. These flights start at 42% lower than the current average price 3 months from now.

  • Can I find deals for flights from St. Louis to Gainesville that include hotel bookings?

    Yes. In addition to deals on St. Louis to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Gainesville.

  • Can I find deals for business class flights from St. Louis to Gainesville?

    Yes. Cheapflights offers flight deals from St. Louis to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Gainesville?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Gainesville (average of $54). Flying from St. Louis to Gainesville in September is currently the most expensive (average of $118). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Gainesville

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Orlando flights
St. Louis to Miami flights
Kansas City to Orlando flights
Kansas City to Miami flights
St. Louis to Fort Lauderdale flights
Kansas City to Tampa flights
Kansas City to Fort Lauderdale flights
St. Louis to Tampa flights
St. Louis to Fort Myers flights
Kansas City to Fort Myers flights
Springfield to Orlando flights
St. Louis to Sarasota flights
St. Louis to Key West flights
St. Louis to Jacksonville flights
Kansas City to Pensacola flights
St. Louis to West Palm Beach flights
Kansas City to Sarasota flights
Kansas City to Jacksonville flights
Springfield to Miami flights
Kansas City to Panama City flights
St. Louis to Panama City flights
Kansas City to Key West flights
St. Louis to Pensacola flights
Kansas City to West Palm Beach flights
Springfield to Tampa flights
Kansas City to Valparaiso flights
Kansas City to St Petersburg flights
Springfield to Fort Myers flights
Springfield to Fort Lauderdale flights
Springfield to Sarasota flights
Joplin to Sarasota flights
Springfield to Jacksonville flights
St. Louis to Valparaiso flights
St. Louis to Melbourne flights
Springfield to Panama City flights
Columbia to Miami flights
Columbia to Orlando flights
Kansas City to Daytona Beach flights
Kansas City to Melbourne flights
Joplin to Tampa flights
Springfield to St Petersburg flights
Springfield to Pensacola flights
St. Louis to Daytona Beach flights
Joplin to Orlando flights
Springfield to Daytona Beach flights
Springfield to Key West flights
Kansas City to Gainesville flights
St. Louis to Tallahassee flights
Joplin to Pensacola flights
Columbia to Tampa flights

Top 2 airlines flying from St. Louis to Gainesville

Discover the top 2 airlines that operate flights from St. Louis to Gainesville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$387FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$278Average$385FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.