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$368+ Cheap flights from St. Louis to Gainesville (STL - GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GNV
Apr 17 — Apr 241
Fri 4/17
Fri 4/24
1 adult, Economy
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Cheap flight deals from St. Louis to Gainesville

Cheapest flights from St. Louis to Gainesville
Explore the most affordable flight options available from St. Louis to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 18, 2026.

This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:25 am
STL
-
GNV
1 stop4h 51m
Delta
Wed 4/227:03 pm
GNV
-
STL
1 stop5h 33m
Delta
Deal found 3/16$397
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:55 pm
STL
-
GNV
2 stops8h 24m
American Airlines
Wed 4/226:00 am
GNV
-
STL
1 stop5h 16m
American Airlines
Deal found 3/16$431
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:42 am
STL
-
GNV
1 stop5h 35m
Delta
Mon 4/277:03 pm
GNV
-
STL
1 stop5h 33m
Delta
Deal found 3/17$447
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/314:13 pm
STL
-
GNV
1 stop5h 47m
American Airlines
Sat 4/46:24 am
GNV
-
STL
1 stop7h 18m
American Airlines
Deal found 3/16$475
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:35 am
STL
-
GNV
1 stop5h 10m
American Airlines
Sat 4/43:09 pm
GNV
-
STL
1 stop5h 21m
American Airlines
Deal found 3/16$476
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:15 pm
STL
-
GNV
1 stop4h 29m
Delta
Mon 5/187:05 pm
GNV
-
STL
1 stop5h 54m
Delta
Deal found 3/13$493
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:03 am
STL
-
GNV
1 stop4h 44m
Delta
Sun 3/297:00 pm
GNV
-
STL
1 stop5h 58m
Delta
Deal found 3/14$496
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/281:36 pm
STL
-
GNV
1 stop4h 44m
American Airlines
Wed 4/14:15 pm
GNV
-
STL
1 stop7h 43m
American Airlines
Deal found 3/13$501

Find flight deals from St. Louis to Gainesville

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Gainesville (GNV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$397
(Delta)

One-way from

$368
(American Airlines)

Popular in

March

Cheapest in

April

Average price

$1,059
Provider with most accurate pricing for Lambert-St Louis-Gainesville Regional flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Gainesville Regional flights.
Search Deals
From Lambert-St Louis to Gainesville Regional
Search Deals
One-way flight from Lambert-St Louis to Gainesville Regional
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($109 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 14% potential price decrease ($60 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from St. Louis to Gainesville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Wed 4/15

7:25 am-1:16 pm

1 stop4h 51m

Gainesville Regional

Wed 4/22

7:03 pm-11:36 pm

1 stop5h 33m

$397

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Wed 4/15

12:55 pm-10:19 pm

2 stops8h 24m

Gainesville Regional

Wed 4/22

6:00 am-10:16 am

1 stop5h 16m

$431

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Thu 4/23

11:42 am-6:17 pm

1 stop5h 35m

Gainesville Regional

Mon 4/27

7:03 pm-11:36 pm

1 stop5h 33m

$447

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Fri 4/10

7:03 am-12:47 pm

1 stop4h 44m

Gainesville Regional

Fri 4/17

6:00 am-11:56 am

1 stop6h 56m

$467

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Tue 3/31

4:13 pm-11:00 pm

1 stop5h 47m

Gainesville Regional

Sat 4/4

6:24 am-12:42 pm

1 stop7h 18m

$475

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Sat 3/28

1:36 pm-7:20 pm

1 stop4h 44m

Gainesville Regional

Wed 4/1

6:24 am-2:56 pm

2 stops9h 32m

$506

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Thu 4/23

6:29 am-2:41 pm

2 stops7h 12m

Gainesville Regional

Mon 4/27

5:14 pm-10:59 pm

1 stop6h 45m

$556
Cheapest one-way
Quickest one-way

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Tue 4/14

3:24 pm-9:44 pm

1 stop5h 20m

$368

St. LouisGainesville

STL - GNV

STLGNV

Lambert-St Louis

Thu 4/2

4:13 pm-11:00 pm

1 stop5h 47m

$388

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/17

Sorted by cheapest first

Compare providers for flights from St. Louis to Gainesville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Gainesville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Gainesville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Gainesville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Gainesville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Gainesville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Gainesville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Gainesville

What is the cheapest month to book a flight from St. Louis to Gainesville?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Gainesville (average of $50). Flying from St. Louis to Gainesville in September is currently the most expensive (average of $118). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Gainesville

Get insights into the airlines that provide service to Gainesville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Gainesville. Reviews last updated March 18, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from St. Louis to Gainesville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,286 reviews

Overall

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
Delta
7.9
Good
8,286 reviews
Delta
7.9
Good
8,286 reviews

Overall

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
American Airlines
7.1
Good
11,468 reviews
Delta
7.9
Good
8,286 reviews

Overall

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Gainesville?

    For as low as $397, Delta can have you in Gainesville from St. Louis in 4h 51m. Airlines will cover a distance of 777 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from St. Louis to Gainesville round-trip?

    Flying on Delta is currently your cheapest option to Gainesville, with prices starting at $248. Another option worth looking into is American Airlines, starting at $278 round trip. These flights start at 46% lower than the current average price 3 months from now.

  • Can I find deals for flights from St. Louis to Gainesville that include hotel bookings?

    Yes. In addition to deals on St. Louis to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Gainesville.

  • Can I find deals for business class flights from St. Louis to Gainesville?

    Yes. Cheapflights offers flight deals from St. Louis to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Gainesville?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Gainesville (average of $50). Flying from St. Louis to Gainesville in September is currently the most expensive (average of $118). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

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Top 2 airlines flying from St. Louis to Gainesville

Discover the top 2 airlines that operate flights from St. Louis to Gainesville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$387FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$278Average$440FlexibilityNo cancel feeOn-time71%

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