$333+ Cheap flights from St. Louis to Gainesville (STL - GNV)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GNV
Sep 10 — Sep 171
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Gainesville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Gainesville
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to GainesvilleExplore the most affordable flight options available from St. Louis to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2026.
Explore the most affordable flight options available from St. Louis to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2026.
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/239:08 am -
1 stop7h 16m
Tue 12/15:55 pm -
1 stop7h 03m
Deal found 8/11![American Airlines logo]()
$420
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
1 stop5h 39m
Mon 10/127:03 pm -
1 stop5h 51m
Deal found 8/10![Delta logo]()
$457
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:45 pm -
1 stop5h 11m
Sun 9/65:19 pm -
1 stop7h 23m
Deal found 8/9![American Airlines logo]()
$465
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:00 am -
1 stop5h 13m
Tue 9/86:05 am -
1 stop4h 29m
Deal found 8/10![Delta logo]()
$475
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:52 pm -
1 stop4h 24m
Fri 9/41:08 pm -
1 stop5h 45m
Deal found 8/9![Delta logo]()
$507
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:37 pm -
1 stop4h 11m
Mon 11/307:06 pm -
1 stop5h 50m
Deal found 8/7![Delta logo]()
$528
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:32 am -
1 stop14h 45m
Mon 10/267:34 pm -
1 stop5h 25m
Deal found 8/10![American Airlines logo]()
$574
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:25 pm -
1 stop5h 26m
Tue 9/82:51 pm -
2 stops10h 23m
Deal found 8/10![American Airlines logo]()
$584
Best flights from St. Louis to GainesvilleDiscover carefully curated flight deals from St. Louis to Gainesville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2026.
Discover carefully curated flight deals from St. Louis to Gainesville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2026.
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:40 pm -
1 stop5h 51m
Sun 9/206:05 am -
1 stop3h 55m
Deal found 8/7![Delta logo]()
$457
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/239:08 am -
1 stop4h 34m
Tue 12/19:37 am -
2 stops8h 10m
Deal found 8/11![American Airlines logo]()
$481
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
1 stop5h 39m
Mon 10/127:03 pm -
1 stop5h 51m
Deal found 8/10![Delta logo]()
$457
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:00 am -
1 stop5h 13m
Tue 9/86:05 am -
1 stop4h 29m
Deal found 8/10![Delta logo]()
$475
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:32 am -
1 stop14h 45m
Mon 10/267:34 pm -
1 stop5h 25m
Deal found 8/10![American Airlines logo]()
$574
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:52 pm -
1 stop4h 24m
Fri 9/41:08 pm -
1 stop5h 45m
Deal found 8/9![Delta logo]()
$507
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:37 pm -
1 stop4h 11m
Mon 11/307:06 pm -
1 stop5h 50m
Deal found 8/11![Delta logo]()
$528
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop5h 54m
Mon 11/303:53 pm -
1 stop6h 40m
Deal found 8/11![Delta logo]()
$598
Last-minute flights from St. Louis to GainesvilleDiscover last-minute flight deals from St. Louis to Gainesville. Data last updated August 11, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Gainesville. Data last updated August 11, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:52 pm -
1 stop4h 24m
Fri 9/41:08 pm -
1 stop5h 45m
Deal found 8/9![Delta logo]()
$507
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:44 am -
2 stops10h 07m
Fri 9/46:39 pm -
1 stop5h 01m
Deal found 8/9![American Airlines logo]()
$600
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:16 am -
1 stop5h 31m
Wed 9/96:44 am -
1 stop6h 31m
Deal found 8/7![American Airlines logo]()
$803
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:00 am -
1 stop5h 13m
Tue 9/86:05 am -
1 stop4h 29m
Deal found 8/10![Delta logo]()
$475
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:25 pm -
1 stop5h 26m
Tue 9/82:51 pm -
2 stops10h 23m
Deal found 8/10![American Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:45 pm -
1 stop5h 11m
Sun 9/65:19 pm -
1 stop7h 23m
Deal found 8/9![American Airlines logo]()
$465
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:40 pm -
1 stop5h 51m
Sun 9/206:05 am -
1 stop3h 55m
Deal found 8/7![Delta logo]()
$457
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/111:49 pm -
2 stops8h 36m
Sun 9/207:34 pm -
1 stop5h 07m
Deal found 8/7![American Airlines logo]()
$590
One-way flights from St. Louis to GainesvilleSearch for one-way flight options from St. Louis to Gainesville. Find affordable one-way fares based on user searches. Data last updated August 11, 2026.
Search for one-way flight options from St. Louis to Gainesville. Find affordable one-way fares based on user searches. Data last updated August 11, 2026.
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:34 pm -
1 stop6h 40m
Deal found 8/8![American Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:45 am -
2 stops8h 19m
Deal found 8/9![Delta logo]()
$758
Find flight deals from St. Louis to Gainesville
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Gainesville (GNV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $420 (American Airlines) |
One-way from | $333 (American Airlines) |
Popular in | March |
Cheapest in | January |
Average price | $446 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from St. Louis to Gainesville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGainesville
STL Lambert-St Louis - GNV Gainesville Regional
STLGNV
Lambert-St Louis
Fri 9/11
3:40 pm-10:31 pm
1 stop5h 51m
Gainesville Regional
Sun 9/20
6:05 am-9:00 am
1 stop3h 55m
$457
St. LouisGainesville
STL Lambert-St Louis - GNV Gainesville Regional
STLGNV
Lambert-St Louis
Mon 10/5
6:00 am-12:39 pm
1 stop5h 39m
Gainesville Regional
Mon 10/12
7:03 pm-11:54 pm
1 stop5h 51m
$457
Quickest round-trip
St. LouisGainesville
STL Lambert-St Louis - GNV Gainesville Regional
STLGNV
Lambert-St Louis
Fri 9/4
6:00 am-12:13 pm
1 stop5h 13m
Gainesville Regional
Tue 9/8
6:05 am-9:34 am
1 stop4h 29m
$475
St. LouisGainesville
STL Lambert-St Louis - GNV Gainesville Regional
STLGNV
Lambert-St Louis
Mon 11/23
9:08 am-2:42 pm
1 stop4h 34m
Gainesville Regional
Tue 12/1
9:37 am-4:47 pm
2 stops8h 10m
$481
St. LouisGainesville
STL Lambert-St Louis - GNV Gainesville Regional
STLGNV
Lambert-St Louis
Fri 8/28
12:52 pm-6:16 pm
1 stop4h 24m
Gainesville Regional
Fri 9/4
1:08 pm-5:53 pm
1 stop5h 45m
$507
St. LouisGainesville
STL Lambert-St Louis - GNV Gainesville Regional
STLGNV
Lambert-St Louis
Tue 11/24
5:37 pm-10:48 pm
1 stop4h 11m
Gainesville Regional
Mon 11/30
7:06 pm-11:56 pm
1 stop5h 50m
$528
St. LouisGainesville
STL Lambert-St Louis - GNV Gainesville Regional
STLGNV
Lambert-St Louis
Thu 10/22
6:32 am-10:17 pm
1 stop14h 45m
Gainesville Regional
Mon 10/26
7:34 pm-11:59 pm
1 stop5h 25m
$574
St. LouisGainesville
STL Lambert-St Louis - GNV Gainesville Regional
STLGNV
Lambert-St Louis
Fri 11/20
6:00 am-12:54 pm
1 stop5h 54m
Gainesville Regional
Mon 11/30
3:53 pm-9:33 pm
1 stop6h 40m
$598
Cheapest one-way
St. LouisGainesville
STL Lambert-St Louis - GNV Gainesville Regional
STLGNV
Lambert-St Louis
Fri 9/25
3:34 pm-11:14 pm
1 stop6h 40m
$333
Quickest one-way
St. LouisGainesville
STL Lambert-St Louis - GNV Gainesville Regional
STLGNV
Lambert-St Louis
Thu 12/24
9:00 am-4:04 pm
1 stop6h 04m
$333
Sorted by cheapest first
Compare providers for flights from St. Louis to Gainesville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Gainesville in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Gainesville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Gainesville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Gainesville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Gainesville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Gainesville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Gainesville
Have a flexible travel schedule? Discover the best time to fly to Gainesville from St. Louis with our price prediction graph.
STL-GNV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Gainesville
Get insights into the airlines that provide service to Gainesville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Gainesville. Reviews last updated August 11, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from St. Louis to Gainesville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Comfort
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Overall
7.8
Comfort
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Overall
7.8
Comfort
7.8
Food
7.2
Crew
8.5
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Gainesville?
Book flights to Gainesville if you plan to visit one of these locationsLake City
Alachua
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Other flights to Gainesville
Explore flights to Gainesville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 11, 2026.
St. Louis and Gainesville flights
Browse other St. Louis and Gainesville flight options. Last updated on August 11, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on August 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from St. Louis to Gainesville
Discover the top 2 airlines that operate flights from St. Louis to Gainesville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$366 | Average$522 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$376 | Average$738 | FlexibilityNo cancel fee | On-timeN/A |