HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florida Keys

$64+ Cheap flights from Iowa to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — EYW
Dec 4 — Dec 111
Thu 12/4
Thu 12/11
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Iowa to Florida Keys with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Iowa to Florida Keys

Keep the following information in mind while searching for Iowa to Florida Keys flight deals. Data was last updated November 4, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$130
(Frontier)

One-way from

$64
(Trip.com)

Popular in

March

Cheapest in

June

Average price

$413
Provider with most accurate pricing for Des Moines-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Miami flights.
Search Deals
From Iowa to Florida Keys
Search Deals
One-way flight from Iowa to Florida Keys
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Iowa to Florida Keys

Cheapest flights from Iowa to Florida Keys
Explore the most affordable flight options available from Iowa to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1711:29 amOMA - MIA
1 stop12h 05mFrontier
Thu 11/208:36 amMIA - OMA
1 stop11h 51mFrontier
Deal found 11/3$130
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/18:36 pmOMA - MIA
1 stop7h 34mFrontier
Fri 12/55:30 amMIA - OMA
1 stop11h 58mFrontier
Deal found 11/4$138
This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/168:26 pmCID - MIA
1 stop8h 53mFrontier
Thu 11/208:36 amMIA - CID
1 stop12h 10mFrontier
Deal found 11/2$138
This Frontier deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:50 pmOMA - MIA
1 stop5h 56mFrontier
Mon 12/85:30 amMIA - OMA
1 stop10h 58mFrontier
Deal found 11/1$142
This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:58 pmDSM - MIA
1 stop8h 21mFrontier
Mon 1/126:25 amMIA - DSM
1 stop14h 05mFrontier
Deal found 11/3$146
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/144:21 pmDSM - MIA
1 stop7h 34mMultiple Airlines
Sun 1/117:35 amMIA - DSM
1 stop15h 34mMultiple Airlines
Deal found 11/3$178
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:15 amDSM - MIA
1 stop5h 10mSouthwest
Tue 12/91:45 pmMIA - DSM
1 stop7h 10mSouthwest
Deal found 11/2$179
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1711:29 amOMA - MIA
1 stop12h 05mFrontier
Mon 11/245:30 amMIA - OMA
1 stop6h 01mFrontier
Deal found 11/4$183
This Expedia deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1011:29 amOMA - MIA
1 stop12h 05mFrontier
Mon 11/175:05 amMIA - OMA
1 stop6h 29mFrontier
Deal found 11/3$184
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/248:00 amDSM - MIA
1 stop9h 45mSouthwest
Fri 12/54:55 pmMIA - DSM
1 stop5h 40mSouthwest
Deal found 11/4$189
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:15 amDSM - MIA
1 stop5h 10mSouthwest
Tue 12/161:45 pmMIA - DSM
1 stop7h 10mSouthwest
Deal found 11/4$198
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/33:18 pmDSM - MIA
1 stop6h 00mAmerican Airlines
Wed 12/108:50 pmMIA - DSM
Nonstop3h 39mAmerican Airlines
Deal found 11/3$212

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Iowa to Florida Keys that are best for you.

Fly from

Iowa

Fly to

Florida Keys

Route

Depart

Return

Price

Cedar RapidsMiami

CID - MIA

CIDMIA

Cedar Rapids

Sun 11/16

8:26 pm-6:19 am

1 stop8h 53m

Miami

Thu 11/20

8:36 am-7:46 pm

1 stop12h 10m

$138

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 12/2

6:33 pm-12:46 am

1 stop5h 13m

Miami

Tue 12/9

11:38 am-7:43 pm

1 stop9h 05m

$217

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 12/2

6:15 am-12:25 pm

1 stop5h 10m

Miami

Tue 12/9

1:05 pm-9:35 pm

2 stops9h 30m

$245

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Mon 1/5

6:44 pm-11:20 am

1 stop15h 36m

Key West

Sun 1/11

2:25 pm-8:25 am

1 stop19h 00m

$248

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Tue 1/27

5:35 am-11:31 am

1 stop4h 56m

Key West

Wed 1/28

2:45 pm-9:51 pm

1 stop8h 06m

$251

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Mon 11/24

8:00 am-6:45 pm

1 stop9h 45m

Miami

Wed 12/3

11:40 am-9:35 pm

2 stops10h 55m

$255

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Wed 1/7

1:26 pm-11:56 pm

2 stops9h 30m

Key West

Tue 1/13

4:01 pm-10:15 pm

1 stop7h 14m

$256

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 1/17

3:00 pm-10:35 pm

1 stop6h 35m

Miami

Sat 1/24

7:15 am-4:14 pm

1 stop9h 59m

$257

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 12/6

3:08 pm-9:10 pm

1 stop5h 02m

Miami

Tue 12/9

2:11 pm-8:50 pm

1 stop7h 39m

$257

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Wed 12/3

7:00 am-2:45 pm

1 stop6h 45m

Miami

Sat 12/6

8:05 am-2:23 pm

1 stop7h 18m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Iowa to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Florida Keys

What is the cheapest month to book a flight from Iowa to Florida Keys?

Currently, July is the cheapest month in which you can book a flight from Iowa to Florida Keys (average of $82). Flying from Iowa to Florida Keys in March is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Florida Keys?

    Frontier, Delta, and Southwest can get you from Iowa to Florida Keys in just under 5h 10m. Your travel time can differ by up to 3h 43m. The distance from Iowa to Florida Keys is about 1328 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Iowa to Florida Keys one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $69. However, be on the lookout for offers from Southwest and Allegiant Air, as they are both options that can get you from Iowa to Florida Keys for a low price.

  • Can I find deals for flights from Iowa to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Iowa to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Florida Keys.

  • Can I find deals for business class flights from Iowa to Florida Keys?

    Yes. Cheapflights offers flight deals from Iowa to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Florida Keys?

    Currently, July is the cheapest month in which you can book a flight from Iowa to Florida Keys (average of $82). Flying from Iowa to Florida Keys in March is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Fort Lauderdale flights
John F Kennedy Intl to Fort Lauderdale flights
John F Kennedy Intl to Miami flights
Newark to Miami flights
LaGuardia to Fort Lauderdale flights
John F Kennedy Intl to Orlando flights
LaGuardia to Miami flights
Newark to Orlando flights
Dallas/Fort Worth to Orlando flights
John F Kennedy Intl to West Palm Beach flights
LaGuardia to Orlando flights
John F Kennedy Intl to Tampa flights
Newark to West Palm Beach flights
Dulles Intl to Miami flights
Reagan-National to Orlando flights
LaGuardia to West Palm Beach flights
Philadelphia to Orlando flights
LaGuardia to Tampa flights
Boston to Fort Lauderdale flights
Newark to Tampa flights
Boston to Orlando flights
Reagan-National to Miami flights
Baltimore to Fort Lauderdale flights
Boston to Miami flights
Boston to Tampa flights
Los Angeles to Orlando flights
O'Hare Intl to Orlando flights
Los Angeles to Miami flights
Philadelphia to Fort Lauderdale flights
Dulles Intl to Orlando flights
O'Hare Intl to Miami flights
Los Angeles to Fort Lauderdale flights
O'Hare Intl to Tampa flights
Minneapolis to Orlando flights
Cleveland to Orlando flights
Detroit to Fort Lauderdale flights
O'Hare Intl to Fort Lauderdale flights
Detroit to Orlando flights
Seattle to Orlando flights
John F Kennedy Intl to Fort Myers flights
Baltimore to Orlando flights
Denver to Orlando flights
Providence to Orlando flights
Boston to West Palm Beach flights
Minneapolis to Miami flights
Newark to Fort Myers flights
Dulles Intl to Fort Lauderdale flights
Dallas/Fort Worth to Miami flights
Hartford to Orlando flights
Philadelphia to Miami flights

Top 4 airlines flying from Iowa to Florida Keys

Discover the top 4 airlines that operate flights from Iowa to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$76Average$157FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$259Average$469FlexibilityNo cancel feeOn-time71%
DeltaCheapest$268Average$411FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$281Average$545FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.