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Florida Keys

$73+ Cheap flights from Iowa to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — EYW
Jan 21 — Jan 281
Wed 1/21
Wed 1/28
1 adult, Economy
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Cheap flight deals from Iowa to Florida Keys

Cheapest flights from Iowa to Florida Keys
Explore the most affordable flight options available from Iowa to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 22, 2025.

This Southwest deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:45 amOMA - MIA
2 stops12h 00mSouthwest
Sat 12/277:30 pmMIA - OMA
1 stop5h 40mSouthwest
Deal found 12/21$346
This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:32 amOMA - MIA
Nonstop3h 48mAmerican Airlines
Tue 12/309:06 pmMIA - OMA
Nonstop3h 49mAmerican Airlines
Deal found 12/20$353
This Southwest deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:15 amDSM - MIA
2 stops8h 55mSouthwest
Sat 12/277:50 pmMIA - DSM
1 stop5h 05mSouthwest
Deal found 12/19$364
This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:45 amOMA - MIA
1 stop8h 52mUnited Airlines
Tue 12/304:43 pmMIA - OMA
1 stop6h 39mUnited Airlines
Deal found 12/20$368
This Delta deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:41 amOMA - MIA
1 stop5h 42mDelta
Wed 12/316:25 amMIA - OMA
1 stop6h 14mDelta
Deal found 12/20$373
This WAYA deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/294:35 pmOMA - MIA
1 stop7h 16mMultiple Airlines
Mon 1/58:00 amMIA - OMA
1 stop8h 40mMultiple Airlines
Deal found 12/21$379
This Delta deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:35 amDSM - MIA
1 stop5h 04mDelta
Wed 12/314:01 pmMIA - DSM
1 stop5h 44mDelta
Deal found 12/20$393
This Southwest deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2112:00 pmOMA - MIA
1 stop6h 05mSouthwest
Sat 12/277:10 amMIA - OMA
1 stop4h 55mSouthwest
Deal found 12/20$420
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:40 amCID - MIA
1 stop7h 43mAmerican Airlines
Tue 12/305:14 pmMIA - CID
1 stop7h 36mAmerican Airlines
Deal found 12/21$433
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:00 amCID - MIA
2 stops13h 40mUnited Airlines
Tue 12/304:06 pmMIA - CID
1 stop6h 28mUnited Airlines
Deal found 12/21$438
This Delta deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:58 pmMLI - MIA
1 stop6h 48mDelta
Sun 12/284:01 pmMIA - MLI
1 stop7h 29mDelta
Deal found 12/19$439
This Frontier deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:48 pmCID - MIA
1 stop8h 12mFrontier
Wed 12/316:05 amMIA - CID
1 stop13h 48mFrontier
Deal found 12/21$442

Find flight deals from Iowa to Florida Keys

Keep the following information in mind while searching for Iowa to Florida Keys flight deals. Data was last updated December 22, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$182
(Orbitz)

One-way from

$73
(Trip.com)

Popular in

March

Cheapest in

June

Average price

$357
Provider with most accurate pricing for Des Moines-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Miami flights.
Search Deals
From Iowa to Florida Keys
Search Deals
One-way flight from Iowa to Florida Keys
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2025.
Use the filters below to find and compare flights from Iowa to Florida Keys that are best for you.

Fly from

Iowa

Fly to

Florida Keys

Route

Depart

Return

Price

Cedar RapidsMiami

CID - MIA

CIDMIA

Cedar Rapids

Thu 2/26

8:07 pm-5:14 am

1 stop8h 07m

Miami

Mon 3/2

6:25 am-7:12 pm

1 stop13h 47m

$182

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Sat 2/28

6:10 am-5:50 pm

1 stop10h 40m

Miami

Sat 3/7

6:25 am-11:30 am

1 stop6h 05m

$213

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 2/3

12:06 pm-10:03 pm

1 stop8h 57m

Miami

Tue 2/10

12:00 pm-4:28 pm

1 stop5h 28m

$237

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Wed 2/4

12:25 pm-10:03 pm

1 stop8h 38m

Miami

Wed 2/11

5:30 pm-10:29 pm

1 stop5h 59m

$237

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 2/21

3:10 pm-12:20 am

1 stop8h 10m

Miami

Wed 2/25

12:55 pm-9:20 pm

2 stops9h 25m

$241

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Wed 2/11

4:00 pm-11:59 pm

1 stop6h 59m

Miami

Wed 2/18

1:45 pm-8:06 pm

1 stop7h 21m

$257

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Tue 2/17

5:20 am-11:30 am

1 stop5h 10m

Miami

Wed 2/18

2:35 pm-9:20 pm

1 stop7h 45m

$257

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Wed 1/21

5:50 am-4:10 pm

2 stops9h 20m

Miami

Wed 1/28

2:00 pm-9:00 pm

1 stop8h 00m

$262

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Mon 1/26

6:14 pm-5:54 pm

2 stops22h 40m

Miami

Fri 1/30

5:30 am-5:19 pm

1 stop12h 49m

$263

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Mon 1/19

9:00 am-5:59 pm

1 stop7h 59m

Miami

Tue 1/27

5:50 am-10:05 am

1 stop5h 15m

$268

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 60 results
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Best time to book a flight from Iowa to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Florida Keys

What is the cheapest month to book a flight from Iowa to Florida Keys?

Currently, July is the cheapest month in which you can book a flight from Iowa to Florida Keys (average of $80). Flying from Iowa to Florida Keys in June is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Florida Keys?

    Frontier, Southwest, and Delta can get you from Iowa to Florida Keys in just under 8h 07m. Your travel time can differ by up to 2h 33m. The distance from Iowa to Florida Keys is about 1287 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Iowa to Florida Keys one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $99. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Iowa to Florida Keys for a low price.

  • Can I find deals for flights from Iowa to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Iowa to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Florida Keys.

  • Can I find deals for business class flights from Iowa to Florida Keys?

    Yes. Cheapflights offers flight deals from Iowa to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Florida Keys?

    Currently, July is the cheapest month in which you can book a flight from Iowa to Florida Keys (average of $80). Flying from Iowa to Florida Keys in June is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to Florida Keys

Discover the top 4 airlines that operate flights from Iowa to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$76Average$174FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$230Average$623FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$259Average$477FlexibilityNo cancel feeOn-time71%
DeltaCheapest$268Average$423FlexibilityNo cancel feeOn-timeN/A

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