HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florida Keys

$70+ Cheap flights from Iowa to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — EYW
Mar 7 — Mar 141
Sat 3/7
Sat 3/14
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Iowa to Florida Keys with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Iowa to Florida Keys

Cheapest flights from Iowa to Florida Keys
Explore the most affordable flight options available from Iowa to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.

This Priceline deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/28:07 pm
CID
-
MIA
1 stop8h 07m
Frontier
Mon 3/95:50 am
MIA
-
CID
1 stop10h 37m
Frontier
Deal found 2/2$183
This Frontier deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:07 pm
CID
-
MIA
1 stop8h 41m
Frontier
Thu 2/266:45 am
MIA
-
CID
1 stop13h 27m
Frontier
Deal found 2/2$190
This Frontier deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/237:17 pm
DSM
-
MIA
1 stop9h 31m
Frontier
Thu 2/266:45 am
MIA
-
DSM
1 stop12h 57m
Frontier
Deal found 2/2$190
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/227:15 pm
CID
-
MIA
1 stop8h 59m
Frontier
Thu 2/266:45 am
MIA
-
CID
1 stop13h 27m
Frontier
Deal found 2/2$204
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/227:45 pm
DSM
-
MIA
1 stop8h 29m
Frontier
Thu 2/266:45 am
MIA
-
DSM
1 stop12h 57m
Frontier
Deal found 2/3$204
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:17 pm
DSM
-
MIA
2 stops15h 59m
Multiple Airlines
Sat 3/75:50 am
MIA
-
DSM
1 stop14h 26m
Multiple Airlines
Deal found 2/2$212
This Frontier deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/168:07 pm
CID
-
MIA
1 stop8h 07m
Frontier
Thu 2/266:45 am
MIA
-
CID
1 stop13h 27m
Frontier
Deal found 2/1$214
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:59 pm
DSM
-
MIA
2 stops37h 24m
Frontier
Sat 3/75:50 am
MIA
-
DSM
1 stop14h 26m
Frontier
Deal found 2/1$218
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:00 am
DSM
-
MIA
1 stop25h 34m
Multiple Airlines
Wed 4/151:34 pm
MIA
-
DSM
1 stop25h 12m
Multiple Airlines
Deal found 2/2$222
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:11 pm
CID
-
MIA
2 stops39h 29m
Multiple Airlines
Mon 3/95:50 am
MIA
-
CID
1 stop10h 37m
Multiple Airlines
Deal found 2/2$223
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
DSM
-
MIA
2 stops27h 34m
Multiple Airlines
Wed 4/110:39 am
MIA
-
DSM
1 stop28h 07m
Multiple Airlines
Deal found 2/4$223
This Expedia deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:17 pm
DSM
-
MIA
1 stop8h 57m
Frontier
Thu 3/56:45 am
MIA
-
DSM
1 stop12h 57m
Frontier
Deal found 2/3$225

Find flight deals from Iowa to Florida Keys

Keep the following information in mind while searching for Iowa to Florida Keys flight deals. Data was last updated February 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$183
(Priceline)

One-way from

$70
(Priceline)

Popular in

March

Cheapest in

June

Average price

$461
Provider with most accurate pricing for Des Moines-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Miami flights.
Search Deals
From Iowa to Florida Keys
Search Deals
One-way flight from Iowa to Florida Keys
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($49 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Iowa to Florida Keys that are best for you.

Fly from

Iowa

Fly to

Florida Keys

Route

Depart

Return

Price

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 2/24

10:57 am-5:56 pm

1 stop5h 59m

Miami

Wed 2/25

11:33 am-7:33 pm

1 stop9h 00m

$251

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 2/28

8:00 am-9:59 pm

2 stops12h 59m

Miami

Wed 3/4

4:45 pm-10:27 pm

1 stop6h 42m

$252

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Tue 2/24

8:00 am-10:19 pm

2 stops13h 19m

Miami

Wed 2/25

10:58 am-6:54 pm

1 stop8h 56m

$256

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Wed 2/25

1:50 pm-11:33 pm

1 stop8h 43m

Miami

Sat 2/28

6:00 am-2:26 pm

2 stops9h 26m

$256

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Wed 4/1

5:30 am-3:47 pm

2 stops9h 17m

Miami

Wed 4/8

9:00 am-8:34 pm

2 stops12h 34m

$267

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 3/10

2:04 pm-11:59 pm

2 stops8h 55m

Miami

Wed 3/18

6:00 am-2:24 pm

2 stops9h 24m

$267

OmahaKey West

OMA - EYW

OMAEYW

Omaha Eppley Airfield

Wed 3/18

3:00 pm-10:37 pm

1 stop6h 37m

Key West

Wed 3/25

4:40 pm-12:15 am

1 stop8h 35m

$283

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 2/28

1:50 pm-11:33 pm

1 stop8h 43m

Miami

Fri 3/6

9:00 am-10:44 am

1 stop26h 44m

$286

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Tue 4/7

9:15 am-6:19 pm

1 stop8h 04m

Key West

Tue 4/14

6:49 pm-11:54 pm

1 stop6h 05m

$289

Cedar RapidsMiami

CID - MIA

CIDMIA

Cedar Rapids

Tue 4/14

8:00 am-2:57 pm

1 stop5h 57m

Miami

Wed 4/22

4:13 pm-9:43 pm

1 stop6h 30m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Iowa to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Florida Keys

What is the cheapest month to book a flight from Iowa to Florida Keys?

Currently, July is the cheapest month in which you can book a flight from Iowa to Florida Keys (average of $82). Flying from Iowa to Florida Keys in December is currently the most expensive (average of $322). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Florida Keys?

    Delta, United Airlines, and American Airlines can get you from Iowa to Florida Keys in just under 5h 59m. Your travel time can differ by up to 7h. The distance from Iowa to Florida Keys is about 1328 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Iowa to Florida Keys one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $99. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Iowa to Florida Keys for a low price.

  • Can I find deals for flights from Iowa to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Iowa to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Florida Keys.

  • Can I find deals for business class flights from Iowa to Florida Keys?

    Yes. Cheapflights offers flight deals from Iowa to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Florida Keys?

    Currently, July is the cheapest month in which you can book a flight from Iowa to Florida Keys (average of $82). Flying from Iowa to Florida Keys in December is currently the most expensive (average of $322). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Miami flights
John F Kennedy Intl to Fort Lauderdale flights
Newark to Fort Lauderdale flights
Newark to Miami flights
LaGuardia to Miami flights
LaGuardia to Fort Lauderdale flights
John F Kennedy Intl to Orlando flights
Newark to West Palm Beach flights
John F Kennedy Intl to West Palm Beach flights
Newark to Orlando flights
John F Kennedy Intl to Tampa flights
Newark to Tampa flights
Boston to Fort Lauderdale flights
LaGuardia to Orlando flights
LaGuardia to Tampa flights
Dulles Intl to Miami flights
Boston to Miami flights
Reagan-National to Miami flights
Detroit to Orlando flights
Reagan-National to Orlando flights
Boston to Tampa flights
Baltimore to Miami flights
Dulles Intl to Orlando flights
Detroit to Fort Lauderdale flights
Baltimore to Fort Lauderdale flights
O'Hare Intl to Orlando flights
Boston to Orlando flights
LaGuardia to West Palm Beach flights
Minneapolis to Orlando flights
Dulles Intl to Fort Lauderdale flights
Philadelphia to Orlando flights
Philadelphia to Miami flights
O'Hare Intl to Fort Lauderdale flights
Baltimore to Orlando flights
Newark to Fort Myers flights
Philadelphia to Fort Lauderdale flights
Philadelphia to Tampa flights
O'Hare Intl to Miami flights
Minneapolis to Fort Myers flights
John F Kennedy Intl to Fort Myers flights
Los Angeles to Miami flights
Boston to West Palm Beach flights
Reagan-National to Fort Lauderdale flights
Los Angeles to Orlando flights
Dulles Intl to Tampa flights
Cleveland to Orlando flights
Dallas/Fort Worth to Orlando flights
Minneapolis to Miami flights
Detroit to Miami flights
Boston to Fort Myers flights

Top 4 airlines flying from Iowa to Florida Keys

Discover the top 4 airlines that operate flights from Iowa to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$76Average$174FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$259Average$476FlexibilityNo cancel feeOn-time71%
DeltaCheapest$268Average$423FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$281Average$459FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights