What are the cheapest airlines to fly from Iowa to Florida Keys one-way?

The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $89. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Iowa to Florida Keys for a low price.

How far in advance should I book a flight from Iowa to Florida Keys?

To save on the cost of your flight from Iowa to Florida Keys, book at least 15 days before your planned departure. Booking around this time can save you about 39% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $364 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $439.

What is the cheapest month to fly from Iowa to Florida Keys?

Flights from Iowa to Florida Keys lean towards being more expensive in March. Prices are generally better when you fly from Iowa to Florida Keys in September, with the cheapest ticket starting at $279.

Can I find deals for flights from Iowa to Florida Keys that include hotel bookings?

Yes. In addition to deals on Iowa to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Iowa to Florida Keys?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Florida Keys.

Can I find deals for business class flights from Iowa to Florida Keys?

Yes. Cheapflights offers flight deals from Iowa to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$89+ Flights from Iowa to Florida Keys - Compare & Save Big

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Cheap flight deals from Iowa to Florida Keys

Most accurate provider	Mytrip 3 stars
Most trusted provider	Mytrip 3 stars
Round-trip from	$217 (American Airlines)
One-way from	$89 (Frontier)
Popular in	March
Cheapest in	September
Average price	$411

Provider with most accurate pricing for Des Moines-Miami flight deals.

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Provider most trusted by Cheapflights users for Des Moines-Miami flights.

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From Iowa to Florida Keys

Search Deals

One-way flight from Iowa to Florida Keys

Search Deals

Highest demand for flights based on searches. 4% potential increase in price ($21 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).

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Average for round-trip flights in April 2025

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Find flight deals from Iowa to Florida Keys

Cheapest flights from Iowa to Florida Keys
Explore the most affordable flight options available from Iowa to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

Thu 5/156:44 amCID - MIA

1 stop6h 45mAmerican Airlines

Mon 5/196:53 pmMIA - CID

1 stop5h 51mAmerican Airlines

Deal found 4/30

$217

Fri 5/166:35 pmDSM - MIA

1 stop5h 02mDelta

Tue 5/203:59 pmMIA - DSM

1 stop7h 31mDelta

Deal found 4/29

$217

Tue 7/224:18 pmCID - MIA

2 stops7h 37mDelta

Tue 7/295:58 pmMIA - CID

1 stop5h 46mDelta

Deal found 4/29

$222

Wed 5/286:45 amDSM - EYW

1 stop6h 52mAmerican Airlines

Wed 6/45:24 pmEYW - DSM

1 stop7h 29mAmerican Airlines

Deal found 4/30

$239

Fri 5/167:20 pmDSM - MIA

1 stop9h 02mFrontier

Fri 5/306:00 amMIA - DSM

1 stop14h 35mFrontier

Deal found 4/28

$248

Tue 7/226:00 amCID - EYW

1 stop6h 08mDelta

Tue 7/296:27 pmEYW - CID

1 stop5h 17mDelta

Deal found 4/29

$251

Tue 9/305:14 amCID - EYW

2 stops10h 34mAmerican Airlines

Tue 10/75:16 pmEYW - CID

1 stop5h 16mAmerican Airlines

Deal found 4/29

$256

Sat 11/82:50 pmOMA - MIA

1 stop6h 54mDelta

Sat 11/156:00 amMIA - OMA

1 stop5h 00mDelta

Deal found 4/30

$257

Sat 11/86:15 amOMA - MIA

2 stops9h 39mUnited Airlines

Tue 11/114:17 pmMIA - OMA

1 stop6h 12mUnited Airlines

Deal found 4/29

$262

Sat 5/245:15 pmCID - EYW

1 stop15h 25mAllegiant Air

Sat 5/313:52 pmEYW - CID

1 stop27h 21mAllegiant Air

Deal found 4/29

$264

Mon 5/199:02 pmOMA - MIA

1 stop7h 20mFrontier

Sun 5/256:00 amMIA - OMA

1 stop14h 06mFrontier

Deal found 4/29

$268

Tue 6/1011:24 amDSM - EYW

1 stop7h 15mDelta

Tue 6/246:29 pmEYW - DSM

1 stop5h 34mDelta

Deal found 4/29

$269

Best flights from Iowa to Florida Keys
Discover carefully curated flight deals from Iowa to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 30, 2025.

Thu 5/156:44 amCID - MIA

1 stop6h 45mAmerican Airlines

Mon 5/196:53 pmMIA - CID

1 stop5h 51mAmerican Airlines

Deal found 4/30

$217

Fri 5/166:35 pmDSM - MIA

1 stop5h 02mDelta

Tue 5/203:59 pmMIA - DSM

1 stop7h 31mDelta

Deal found 4/29

$217

Fri 5/167:20 pmDSM - MIA

1 stop9h 02mFrontier

Fri 5/306:00 amMIA - DSM

1 stop14h 35mFrontier

Deal found 4/28

$248

Sat 5/245:15 pmCID - EYW

1 stop15h 25mAllegiant Air

Sat 5/313:52 pmEYW - CID

1 stop27h 21mAllegiant Air

Deal found 4/29

$264

Wed 5/2810:32 amDSM - MIA

1 stop24h 01mMultiple Airlines

Tue 6/33:15 pmMIA - DSM

3 stops19h 26mMultiple Airlines

Deal found 4/29

$280

Tue 6/106:00 amDSM - MIA

2 stops8h 44mUnited Airlines

Tue 6/173:28 pmMIA - DSM

1 stop9h 26mUnited Airlines

Deal found 4/29

$281

Sat 5/174:30 pmOMA - MIA

1 stop4h 50mSouthwest

Wed 5/218:30 amMIA - OMA

1 stop7h 55mSouthwest

Deal found 4/28

$333

Tue 7/224:18 pmCID - MIA

2 stops7h 37mDelta

Tue 7/295:58 pmMIA - CID

1 stop5h 46mDelta

Deal found 4/29

$222

Wed 5/286:45 amDSM - EYW

1 stop6h 52mAmerican Airlines

Wed 6/45:24 pmEYW - DSM

1 stop7h 29mAmerican Airlines

Deal found 4/30

$239

Mon 5/199:02 pmOMA - MIA

1 stop7h 20mFrontier

Sun 5/256:00 amMIA - OMA

1 stop14h 06mFrontier

Deal found 4/29

$268

Tue 7/226:00 amCID - EYW

1 stop6h 08mDelta

Tue 7/296:27 pmEYW - CID

1 stop5h 17mDelta

Deal found 4/29

$251

Tue 9/305:14 amCID - EYW

2 stops10h 34mAmerican Airlines

Tue 10/75:16 pmEYW - CID

1 stop5h 16mAmerican Airlines

Deal found 4/29

$256

Last-minute flights from Iowa to Florida Keys
Discover last-minute flight deals from Iowa to Florida Keys. Data last updated April 30, 2025 and is based on user searches.

Tue 5/62:15 pmOMA - MIA

1 stop5h 50mSouthwest

Tue 5/138:30 amMIA - OMA

1 stop9h 50mSouthwest

Deal found 4/29

$323

Tue 5/66:00 amOMA - MIA

2 stops8h 54mUnited Airlines

Tue 5/133:18 pmMIA - OMA

1 stop8h 57mUnited Airlines

Deal found 4/29

$328

Tue 5/65:50 amMLI - EYW

1 stop4h 40mDelta

Tue 5/136:25 pmEYW - MLI

1 stop5h 32mDelta

Deal found 4/29

$334

Tue 5/65:00 amMLI - EYW

2 stops10h 52mAmerican Airlines

Tue 5/132:20 pmEYW - MLI

1 stop8h 04mAmerican Airlines

Deal found 4/29

$339

Wed 5/72:17 pmOMA - EYW

1 stop4h 50mDelta

Tue 5/136:25 pmEYW - OMA

1 stop6h 33mDelta

Deal found 4/29

$334

Wed 5/75:00 amOMA - EYW

2 stops10h 52mAmerican Airlines

Tue 5/132:18 pmEYW - OMA

1 stop7h 33mAmerican Airlines

Deal found 4/29

$339

Thu 5/89:02 pmOMA - MIA

1 stop7h 20mFrontier

Mon 5/126:00 amMIA - OMA

1 stop15h 02mFrontier

Deal found 4/29

$310

Fri 5/95:30 amCID - EYW

1 stop6h 26mDelta

Wed 5/146:25 pmEYW - CID

1 stop5h 35mDelta

Deal found 4/30

$349

Fri 5/96:44 amCID - EYW

2 stops8h 56mAmerican Airlines

Wed 5/1412:49 pmEYW - CID

1 stop6h 02mAmerican Airlines

Deal found 4/30

$354

Sat 5/106:44 amCID - MIA

1 stop8h 39mAmerican Airlines

Sat 5/176:53 pmMIA - CID

1 stop5h 51mAmerican Airlines

Deal found 4/30

$237

Sat 5/105:55 amCID - MIA

1 stop7h 59mDelta

Tue 5/135:59 pmMIA - CID

1 stop6h 01mDelta

Deal found 4/30

$242

Sat 5/1011:26 amDSM - MIA

1 stop7h 06mDelta

Sun 5/187:25 amMIA - DSM

1 stop6h 02mDelta

Deal found 4/30

$277

One-way flights from Iowa to Florida Keys
Search for one-way flight options from Iowa to Florida Keys. Find affordable one-way fares based on user searches. Data last updated April 30, 2025.

Mon 5/59:02 pmOMA - MIA

1 stop7h 20mFrontier

Deal found 4/29

$89

Fri 5/97:20 pmDSM - MIA

1 stop9h 02mFrontier

Deal found 4/29

$89

Fri 5/3012:18 pmCID - MIA

1 stop6h 56mAmerican Airlines

Deal found 4/30

$109

Fri 6/136:47 pmDSM - MIA

1 stop5h 10mDelta

Deal found 4/29

$109

Tue 5/276:25 amCID - MIA

1 stop6h 18mDelta

Deal found 4/30

$114

Tue 7/19:15 amOMA - MIA

2 stops12h 24mUnited Airlines

Deal found 4/30

$134

Wed 6/41:32 pmOMA - MIA

2 stops15h 11mMultiple Airlines

Deal found 4/30

$137

Sat 8/26:45 amDSM - MIA

Nonstop3h 24mAmerican Airlines

Deal found 4/29

$139

Tue 6/1010:39 amOMA - EYW

1 stop8h 00mDelta

Deal found 4/29

$142

Tue 6/106:00 amOMA - EYW

2 stops12h 02mAmerican Airlines

Deal found 4/29

$147

Wed 7/305:25 amDSM - MIA

2 stops9h 55mSouthwest

Deal found 4/29

$164

Tue 7/85:05 amOMA - MIA

2 stops10h 15mSouthwest

Deal found 4/30

$167

Cheapflights Fare Finder

Use the filters below to find and compare flights from Iowa to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cedar RapidsMiami

CID - MIA

CIDMIA

Cedar Rapids

Thu 5/15

6:44 am-2:29 pm

1 stop6h 45m

Miami

Mon 5/19

6:53 pm-11:44 pm

1 stop5h 51m

$217

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Fri 5/16

6:35 pm-12:37 am

1 stop5h 02m

Miami

Tue 5/20

3:59 pm-10:30 pm

1 stop7h 31m

$217

Cedar RapidsMiami

CID - MIA

CIDMIA

Cedar Rapids

Tue 7/22

4:18 pm-12:55 am

2 stops7h 37m

Miami

Tue 7/29

5:58 pm-10:44 pm

1 stop5h 46m

$222

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Wed 5/28

6:45 am-2:37 pm

1 stop6h 52m

Key West

Wed 6/4

5:24 pm-11:53 pm

1 stop7h 29m

$239

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Fri 5/16

7:20 pm-5:22 am

1 stop9h 02m

Miami

Fri 5/30

6:00 am-7:35 pm

1 stop14h 35m

$248

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Tue 7/22

6:00 am-1:08 pm

1 stop6h 08m

Key West

Tue 7/29

6:27 pm-10:44 pm

1 stop5h 17m

$251

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Tue 9/30

5:14 am-4:48 pm

2 stops10h 34m

Key West

Tue 10/7

5:16 pm-9:32 pm

1 stop5h 16m

$256

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 7/19

11:43 am-8:43 pm

1 stop8h 00m

Miami

Sat 7/26

6:22 am-10:53 am

1 stop5h 31m

$257

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Sat 5/24

5:15 pm-9:40 am

1 stop15h 25m

Key West

Sat 5/31

3:52 pm-6:13 pm

1 stop27h 21m

$264

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Mon 5/19

9:02 pm-5:22 am

1 stop7h 20m

Miami

Sun 5/25

6:00 am-7:06 pm

1 stop14h 06m

$268

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 57 results

...

Best time to book a flight from Iowa to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Iowa with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Florida Keys

What is the cheapest month to book a flight from Iowa to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Iowa to Florida Keys (average of $328). Flying from Iowa to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to EOA?

When flying from Iowa to Florida Keys, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Florida Keys by month

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

See what other customers who have flown with Alaska Airlines, Southwest and Delta from Iowa to Florida Keys have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

9,968 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Alaska Airlines

8.0

Very good

9,968 reviews

Alaska Airlines

8.0

Very good

9,968 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Southwest

8.0

Very good

4,294 reviews

Alaska Airlines

8.0

Very good

9,968 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Delta

8.0

Very good

7,935 reviews

Alaska Airlines

8.0

Very good

9,968 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

United Airlines

7.4

Good

8,696 reviews

Alaska Airlines

8.0

Very good

9,968 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Allegiant Air

7.3

Good

734 reviews

Alaska Airlines

8.0

Very good

9,968 reviews

Reviews

1 / 20

10.0

Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

What are the cheapest airlines to fly from Iowa to Florida Keys one-way?
The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $89. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Iowa to Florida Keys for a low price.
Can I find deals for flights from Iowa to Florida Keys that include hotel bookings?
Yes. In addition to deals on Iowa to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Iowa to Florida Keys?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Florida Keys.
Can I find deals for business class flights from Iowa to Florida Keys?
Yes. Cheapflights offers flight deals from Iowa to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Iowa to Florida Keys?
Currently, August is the cheapest month in which you can book a flight from Iowa to Florida Keys (average of $328). Flying from Iowa to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Iowa to Florida Keys

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$241	Average$408	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$268	Average$453	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$281	Average$543	FlexibilityNo cancel fee	On-time69%

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$89+ Cheap flights from Iowa to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Iowa to Florida Keys with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Iowa to Florida Keys

Keep the following information in mind while searching for Iowa to Florida Keys flight deals. Data was last updated April 30, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Iowa to Florida Keys

Cheapest flights from Iowa to Florida KeysExplore the most affordable flight options available from Iowa to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

Explore the most affordable flight options available from Iowa to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Iowa to Florida Keys that are best for you.

Best time to book a flight from Iowa to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Iowa with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Florida Keys

What is the cheapest month to book a flight from Iowa to Florida Keys?

What is the cheapest time of day to fly from IA to EOA?

Find hourly flight availability from Iowa to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

Reviews of airlines servicing Florida Keys

See what other customers who have flown with Alaska Airlines, Southwest and Delta from Iowa to Florida Keys have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines to fly from Iowa to Florida Keys one-way?

Can I find deals for flights from Iowa to Florida Keys that include hotel bookings?

How can I find direct flights from Iowa to Florida Keys?

Can I find deals for business class flights from Iowa to Florida Keys?

What is the cheapest month to book a flight from Iowa to Florida Keys?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Iowa to Florida Keys

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Cheapest flights from Iowa to Florida Keys
Explore the most affordable flight options available from Iowa to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.