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Florida Keys

$89+ Cheap flights from Iowa to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/7. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — EYW
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Iowa to Florida Keys

Keep the following information in mind while searching for Iowa to Florida Keys flight deals. Data was last updated July 31, 2025.

Round-trip from

$174
(American Airlines)

One-way from

$89
(Southwest)

Popular in

March

Cheapest in

June

Average price

$462
From Iowa to Florida Keys
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One-way flight from Iowa to Florida Keys
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Highest demand for flights based on searches. 9% potential increase in price ($43 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Iowa to Florida Keys

Cheapest flights from Iowa to Florida Keys
Explore the most affordable flight options available from Iowa to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/236:45 amDSM - MIA
Nonstop3h 30mAmerican Airlines
Sat 8/307:51 pmMIA - DSM
Nonstop3h 39mAmerican Airlines
Deal found 7/30$174
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/168:25 amDSM - MIA
1 stop4h 40mSouthwest
Wed 9/172:50 pmMIA - DSM
1 stop8h 30mSouthwest
Deal found 7/30$184
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1310:20 amDSM - MIA
1 stop7h 31mDelta
Sat 9/206:00 amMIA - DSM
1 stop5h 40mDelta
Deal found 7/30$217
This Frontier deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/97:51 pmOMA - MIA
1 stop9h 39mFrontier
Sat 8/166:00 amMIA - OMA
1 stop13h 53mFrontier
Deal found 7/30$238
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/237:00 amCID - EYW
1 stop6h 05mAmerican Airlines
Tue 8/265:55 pmEYW - CID
1 stop6h 03mAmerican Airlines
Deal found 7/30$251
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/178:00 amDSM - MIA
1 stop11h 35mMultiple Airlines
Thu 10/237:00 amMIA - DSM
2 stops13h 57mMultiple Airlines
Deal found 7/29$251
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/171:45 pmOMA - MIA
1 stop5h 55mSouthwest
Wed 9/249:00 amMIA - OMA
1 stop5h 25mSouthwest
Deal found 7/29$256
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/181:58 pmOMA - MIA
1 stop8h 34mAmerican Airlines
Tue 10/215:10 pmMIA - OMA
1 stop7h 49mAmerican Airlines
Deal found 7/29$257
This Frontier deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:36 pmCID - MIA
1 stop13h 32mFrontier
Sun 12/76:15 amMIA - CID
1 stop8h 22mFrontier
Deal found 7/30$258
This Frontier deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/296:20 pmDSM - MIA
1 stop11h 10mFrontier
Mon 9/16:00 amMIA - DSM
1 stop9h 23mFrontier
Deal found 7/30$258
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/101:49 pmOMA - MIA
1 stop7h 06mUnited Airlines
Wed 9/1712:50 pmMIA - OMA
2 stops11h 09mUnited Airlines
Deal found 7/31$262
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/56:00 amDSM - EYW
1 stop7h 00mAmerican Airlines
Tue 9/912:00 pmEYW - DSM
1 stop5h 49mAmerican Airlines
Deal found 7/30$269

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Iowa to Florida Keys that are best for you.

Fly from

Iowa

Fly to

Florida Keys

Route

Depart

Return

Price

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Sat 8/23

6:45 am-11:15 am

Nonstop3h 30m

Miami

Sat 8/30

7:51 pm-10:30 pm

Nonstop3h 39m

$174

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 9/16

8:25 am-2:05 pm

1 stop4h 40m

Miami

Wed 9/17

2:50 pm-10:20 pm

1 stop8h 30m

$184

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Sat 9/13

5:12 pm-12:23 am

1 stop6h 11m

Miami

Sat 9/20

6:00 am-10:40 am

1 stop5h 40m

$217

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 8/9

7:51 pm-6:30 am

1 stop9h 39m

Miami

Sat 8/16

6:00 am-6:53 pm

1 stop13h 53m

$238

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Fri 10/17

8:00 am-8:35 pm

1 stop11h 35m

Miami

Thu 10/23

7:00 am-7:57 pm

2 stops13h 57m

$251

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Sat 8/23

7:00 am-2:05 pm

1 stop6h 05m

Key West

Tue 8/26

5:55 pm-10:58 pm

1 stop6h 03m

$251

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Wed 9/17

1:45 pm-8:40 pm

1 stop5h 55m

Miami

Wed 9/24

9:00 am-1:25 pm

1 stop5h 25m

$256

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 10/18

1:58 pm-11:32 pm

1 stop8h 34m

Miami

Tue 10/21

5:10 pm-11:59 pm

1 stop7h 49m

$257

Cedar RapidsMiami

CID - MIA

CIDMIA

Cedar Rapids

Thu 12/4

2:36 pm-5:08 am

1 stop13h 32m

Miami

Sun 12/7

6:15 am-1:37 pm

1 stop8h 22m

$258

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Fri 8/29

6:20 pm-6:30 am

1 stop11h 10m

Miami

Mon 9/1

6:00 am-2:23 pm

1 stop9h 23m

$258

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 58 results
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Best time to book a flight from Iowa to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Florida Keys

What is the cheapest month to book a flight from Iowa to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Iowa to Florida Keys (average of $328). Flying from Iowa to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated July 31, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Iowa to Florida Keys. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,900 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Frontier
5.9
Fair
3,239 reviews
Southwest
8.0
Very good
4,246 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Iowa to Florida Keys one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $89. However, be on the lookout for offers from Frontier and Delta, as they are both options that can get you from Iowa to Florida Keys for a low price.

  • Can I find deals for flights from Iowa to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Iowa to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Florida Keys.

  • Can I find deals for business class flights from Iowa to Florida Keys?

    Yes. Cheapflights offers flight deals from Iowa to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Iowa to Florida Keys (average of $328). Flying from Iowa to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to Florida Keys

Discover the top 4 airlines that operate flights from Iowa to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$76Average$157FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$258Average$423FlexibilityNo cancel feeOn-time71%
DeltaCheapest$268Average$439FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$288Average$543FlexibilityNo cancel feeOn-time69%

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