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$155+ Cheap flights from Kentucky to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — FLO
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from Kentucky to Florence

Cheapest flights from Kentucky to Florence
Explore the most affordable flight options available from Kentucky to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:00 amSDF - FLO
1 stop4h 26mAmerican Airlines
Tue 1/66:15 amFLO - SDF
1 stop4h 09mAmerican Airlines
Deal found 12/22$481
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:55 pmCVG - FLO
1 stop4h 10mAmerican Airlines
Sat 1/36:30 pmFLO - CVG
1 stop4h 37mAmerican Airlines
Deal found 12/21$481
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:52 pmLEX - FLO
1 stop3h 13mAmerican Airlines
Thu 1/16:30 pmFLO - LEX
1 stop5h 26mAmerican Airlines
Deal found 12/21$481
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:38 amCVG - FLO
2 stops6h 48mAmerican Airlines
Thu 1/15:15 amFLO - CVG
2 stops9h 33mAmerican Airlines
Deal found 12/21$491
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:00 pmCVG - FLO
1 stop5h 15mAmerican Airlines
Sat 1/36:30 pmFLO - CVG
1 stop4h 37mAmerican Airlines
Deal found 12/21$510
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:26 amCVG - FLO
1 stop4h 00mAmerican Airlines
Fri 1/26:30 pmFLO - CVG
1 stop5h 21mAmerican Airlines
Deal found 12/21$520
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:09 amLEX - FLO
1 stop6h 33mAmerican Airlines
Fri 1/21:07 pmFLO - LEX
1 stop4h 26mAmerican Airlines
Deal found 12/21$520
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:09 amLEX - FLO
1 stop6h 33mAmerican Airlines
Thu 1/112:51 pmFLO - LEX
2 stops9h 14mAmerican Airlines
Deal found 12/21$525
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:00 pmCVG - FLO
1 stop5h 15mAmerican Airlines
Thu 1/16:30 pmFLO - CVG
1 stop5h 21mAmerican Airlines
Deal found 12/21$546
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:05 amLEX - FLO
1 stop4h 37mAmerican Airlines
Thu 1/16:30 pmFLO - LEX
1 stop3h 31mAmerican Airlines
Deal found 12/21$546
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:00 pmCVG - FLO
1 stop5h 15mAmerican Airlines
Fri 1/21:07 pmFLO - CVG
1 stop5h 23mAmerican Airlines
Deal found 12/21$549
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:09 amLEX - FLO
1 stop6h 33mAmerican Airlines
Sat 1/31:07 pmFLO - LEX
2 stops8h 58mAmerican Airlines
Deal found 12/21$558

Find flight deals from Kentucky to Florence

Keep the following information in mind while searching for Kentucky to Florence flight deals. Data was last updated December 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$369
(American Airlines)

One-way from

$155
(American Airlines)
Provider with most accurate pricing for Louisville Intl-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Florence flights.
Search Deals
From Kentucky to Florence
Search Deals
One-way flight from Kentucky to Florence
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Kentucky to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Kentucky to Florence that are best for you.

Fly from

Kentucky

Fly to

Florence

Route

Depart

Return

Price

NashvilleFlorence

BNA - FLO

BNAFLO

Nashville Intl

Fri 3/27

6:32 pm-11:57 pm

1 stop4h 25m

Florence

Sun 3/29

6:20 pm-11:39 pm

1 stop6h 19m

$369

NashvilleFlorence

BNA - FLO

BNAFLO

Nashville Intl

Mon 1/5

5:15 am-12:26 pm

1 stop6h 11m

Florence

Fri 1/9

6:15 am-11:16 am

1 stop6h 01m

$413

NashvilleFlorence

BNA - FLO

BNAFLO

Nashville Intl

Fri 2/6

6:29 pm-10:43 pm

1 stop3h 14m

$155

CincinnatiFlorence

CVG - FLO

CVGFLO

Cincinnati Cinci./N. Kentucky

Sun 12/28

7:00 pm-12:15 am

1 stop5h 15m

$306

LexingtonFlorence

LEX - FLO

LEXFLO

Lexington Blue Grass

Sun 12/28

6:03 pm-12:15 am

1 stop6h 12m

$306

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Best time to book a flight from Kentucky to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Kentucky with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Kentucky to Florence

What is the cheapest month to book a flight from Kentucky to Florence, South Carolina?

Currently, July is the cheapest month in which you can book a flight from Kentucky to Florence, South Carolina (average of $64). Flying from Kentucky to Florence, South Carolina in February is currently the most expensive (average of $146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Kentucky to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Kentucky?

    Located just 2.3 mi from the city center, Florence (FLO) is the airport most travelers will use when flying to Florence from Kentucky.

  • How long is the flight from Kentucky to Florence, South Carolina?

    American Airlines can get you from Kentucky to Florence, South Carolina in just under 4h 25m. Your travel time can differ by up to . Kentucky and Florence, South Carolina are separated by a distance of 415 mi.

  • What are the most popular routes from Kentucky to Florence, South Carolina?

    The most popular route from Kentucky to Florence, South Carolina is Nashville Intl - Florence. You may also consider Cincinnati Cinci./N. Kentucky - Florence or Lexington Blue Grass - Florence.

  • Can I find deals for flights from Kentucky to Florence that include hotel bookings?

    Yes. In addition to deals on Kentucky to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Kentucky to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Kentucky to Florence.

  • Can I find deals for business class flights from Kentucky to Florence?

    Yes. Cheapflights offers flight deals from Kentucky to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Kentucky to Florence, South Carolina?

    Currently, July is the cheapest month in which you can book a flight from Kentucky to Florence, South Carolina (average of $64). Flying from Kentucky to Florence, South Carolina in February is currently the most expensive (average of $146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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