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$239+ Cheap flights from Florida to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/18. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — FLO
Jul 1 — Jul 81
Tue 7/1
Tue 7/8
1 adult, Economy
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Cheap flight deals from Florida to Florence

Keep the following information in mind while searching for Florida to Florence flight deals. Data was last updated June 26, 2025.

Round-trip from

$421
(American Airlines)

One-way from

$305
(American Airlines)
From Florida to Florence
Search Deals
One-way flight from Florida to Florence
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Find flight deals from Florida to Florence

Cheapest flights from Florida to Florence
Explore the most affordable flight options available from Florida to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 26, 2025.

This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/89:57 amFLL - FLO
1 stop4h 12mAmerican Airlines
Mon 12/156:55 amFLO - FLL
1 stop6h 11mAmerican Airlines
Deal found 6/24$421
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/510:20 amMCO - FLO
1 stop6h 52mAmerican Airlines
Mon 9/85:37 pmFLO - MCO
1 stop3h 37mAmerican Airlines
Deal found 6/25$435
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:09 pmTPA - FLO
1 stop3h 31mAmerican Airlines
Mon 12/82:29 pmFLO - TPA
1 stop3h 26mAmerican Airlines
Deal found 6/25$435
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/95:24 pmPBI - FLO
1 stop6h 35mAmerican Airlines
Sun 7/135:07 amFLO - PBI
1 stop6h 00mAmerican Airlines
Deal found 6/24$442
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/95:28 pmMIA - FLO
1 stop6h 31mAmerican Airlines
Sun 7/135:07 amFLO - MIA
1 stop5h 51mAmerican Airlines
Deal found 6/24$473
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/77:44 pmSRQ - FLO
1 stop4h 15mAmerican Airlines
Sun 8/102:34 pmFLO - SRQ
1 stop3h 54mAmerican Airlines
Deal found 6/25$477

Cheapflights Fare Finder

Customize your flight search to find flights from Florida to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2025.
Use the filters below to find and compare flights from Florida to Florence that are best for you.

Fly from

Florida

Fly to

Florence

Route

Depart

Return

Price

Fort LauderdaleFlorence

FLL - FLO

FLLFLO

Fort Lauderdale

Tue 7/8

9:57 am-2:09 pm

1 stop4h 12m

Florence

Mon 12/15

6:55 am-1:06 pm

1 stop6h 11m

$421

OrlandoFlorence

MCO - FLO

MCOFLO

Orlando

Fri 9/5

10:20 am-5:12 pm

1 stop6h 52m

Florence

Mon 9/8

5:37 pm-9:14 pm

1 stop3h 37m

$435

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Thu 12/4

8:09 pm-11:40 pm

1 stop3h 31m

Florence

Mon 12/8

2:29 pm-5:55 pm

1 stop3h 26m

$435

West Palm BeachFlorence

PBI - FLO

PBIFLO

Palm Beach Intl

Tue 8/5

8:17 am-2:09 pm

1 stop5h 52m

Florence

Sat 8/9

11:15 am-4:58 pm

1 stop5h 43m

$457

MiamiFlorence

MIA - FLO

MIAFLO

Miami

Wed 7/9

5:28 pm-11:59 pm

1 stop6h 31m

Florence

Sun 7/13

5:07 am-10:58 am

1 stop5h 51m

$473

SarasotaFlorence

SRQ - FLO

SRQFLO

Sarasota Bradenton Intl

Thu 8/7

7:44 pm-11:59 pm

1 stop4h 15m

Florence

Sun 8/10

2:34 pm-6:28 pm

1 stop3h 54m

$477

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Mon 8/18

12:30 pm-11:02 pm

2 stops10h 32m

$239

Fort LauderdaleFlorence

FLL - FLO

FLLFLO

Fort Lauderdale

Thu 7/3

9:59 am-2:08 pm

1 stop4h 09m

$367

MiamiFlorence

MIA - FLO

MIAFLO

Miami

Mon 9/15

5:18 am-12:02 pm

1 stop6h 44m

$406

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/26

Best time to book a flight from Florida to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Florida with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida to Florence

What is the cheapest month to book a flight from Florida to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Florida to Florence, South Carolina (average of $366). Flying from Florida to Florence, South Carolina in October is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from FL to FLO?

Find hourly flight availability from Florida to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 26, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florida to Florence, South Carolina as you normally would.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated June 26, 2025.
Peruse reviews from past customers who have flown with American Airlines from Florida to Florence to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Entertainment

6.9

Overall

7.2

Comfort

7.2

Food

6.5

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Bama,Oct 2024

MIA - PNS

I paid for first class and it was nothing more than a 36" long curtain between first and business class, nothing extra, nothing fancy and a waste of money. Would have been better off just getting a regular seat and saving the money. Also had one of my eardrums rupture because of the take off and had to sit in uncomfortable pain with a bleeding ear the entire flight. Had to go to the doctor and it's been 5 days and still having difficulty hearing like it just happened.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Entertainment

6.9

Overall

7.2

Comfort

7.2

Food

6.5

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Bama,Oct 2024

MIA - PNS

I paid for first class and it was nothing more than a 36" long curtain between first and business class, nothing extra, nothing fancy and a waste of money. Would have been better off just getting a regular seat and saving the money. Also had one of my eardrums rupture because of the take off and had to sit in uncomfortable pain with a bleeding ear the entire flight. Had to go to the doctor and it's been 5 days and still having difficulty hearing like it just happened.

Related info for your journey

Find useful and relevant information for your journey from Florida to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Florida?

    Florence (FLO) is the airport you will fly into if you book a flight from Florida to Florence. It is only a 2.3 mi journey from Florence (FLO) to Florence’s city center.

  • What are the most popular routes from Florida to Florence, South Carolina?

    When deciding which route to take from Florida to Florence, South Carolina consider Tampa - Florence, Orlando - Florence or Fort Lauderdale - Florence as they are the most popular.

  • Can I find deals for flights from Florida to Florence that include hotel bookings?

    Yes. In addition to deals on Florida to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida to Florence.

  • Can I find deals for business class flights from Florida to Florence?

    Yes. Cheapflights offers flight deals from Florida to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florida to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Florida to Florence, South Carolina (average of $366). Flying from Florida to Florence, South Carolina in October is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florida?

Book flights to Florida if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Top airline flying from Florida to Florence

Discover the top airline that operate flights from Florida to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$315Average$477FlexibilityNo cancel feeOn-time71%

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