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Durham

Cheap flights from Des Moines (DSM) to Durham, NC

DSM — RDU
Oct 28 — Nov 41
Wed 10/28
Wed 11/4
1 adult, Economy
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Find flight deals from Des Moines to Durham

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Popular in

November

Cheapest in

August

Average price

$380
Provider with most accurate pricing for Des Moines-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Raleigh-Durham flights.
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Highest demand for flights based on searches. 18% potential increase in price ($88 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in September 2026
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Reviews of airlines servicing Durham

Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Des Moines to Durham by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,201 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Edward,Sep 2026

MCO - BWI

Changed flight which was easy. Gate Agent booked me from extra leg room seat on original flight to row 15 on new flight that did not have extra leg room - even though it was an exit row. The row in front of me with extra leg room had an empty seat.
Southwest
8.0
Very good
4,201 reviews
Southwest
8.0
Very good
4,201 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Edward,Sep 2026

MCO - BWI

Changed flight which was easy. Gate Agent booked me from extra leg room seat on original flight to row 15 on new flight that did not have extra leg room - even though it was an exit row. The row in front of me with extra leg room had an empty seat.
Delta
7.8
Good
8,605 reviews
Southwest
8.0
Very good
4,201 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Edward,Sep 2026

MCO - BWI

Changed flight which was easy. Gate Agent booked me from extra leg room seat on original flight to row 15 on new flight that did not have extra leg room - even though it was an exit row. The row in front of me with extra leg room had an empty seat.
United Airlines
7.4
Good
10,242 reviews
Southwest
8.0
Very good
4,201 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Edward,Sep 2026

MCO - BWI

Changed flight which was easy. Gate Agent booked me from extra leg room seat on original flight to row 15 on new flight that did not have extra leg room - even though it was an exit row. The row in front of me with extra leg room had an empty seat.
American Airlines
7.0
Good
12,099 reviews
Southwest
8.0
Very good
4,201 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Edward,Sep 2026

MCO - BWI

Changed flight which was easy. Gate Agent booked me from extra leg room seat on original flight to row 15 on new flight that did not have extra leg room - even though it was an exit row. The row in front of me with extra leg room had an empty seat.

Related info for your journey

  • What airport do you fly from for flights from Des Moines to Durham?

    For a flight from Des Moines to Durham, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city. Des Moines is the only Des Moines airport and it handles 0 outbound flights to Durham per day. 4 airlines have flights to Durham from Des Moines on a regular basis.

  • What are the cheapest airlines to fly from Des Moines to Durham one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $135. Users have also found prices from $162 and $189 on American Airlines and Delta, respectively.

  • Can I find deals for flights from Des Moines to Durham that include hotel bookings?

    Yes. In addition to deals on Des Moines to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Durham.

  • Can I find deals for business class flights from Des Moines to Durham?

    Yes. Cheapflights offers flight deals from Des Moines to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Des Moines to Durham

AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$441FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$254Average$386FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$268Average$381FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$309Average$416FlexibilityNo cancel feeOn-time63%

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