$122+ Cheap flights from San Francisco to Des Moines (SFO - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — DSM
Jul 21 — Jul 281
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Des Moines with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
One-way
Cheapest flights from San Francisco to Des MoinesExplore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
Explore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
This Expedia deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Mon 8/172:19 pm
DSM
- SFO
1 stop11h 59m
Frontier
Deal found 6/16![Frontier logo]()
$242
This CheapOair deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:38 pm
SFO
- DSM
1 stop22h 56m
Frontier
Mon 8/172:19 pm
DSM
- SFO
1 stop11h 59m
Frontier
Deal found 6/20![Frontier logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:24 am
SFO
- DSM
1 stop7h 36m
Multiple Airlines
Sun 8/239:50 pm
DSM
- SFO
1 stop24h 06m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:23 pm
SFO
- DSM
2 stops36h 36m
Multiple Airlines
Mon 7/2010:01 pm
DSM
- SFO
1 stop19h 24m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:00 pm
SFO
- DSM
1 stop22h 11m
Multiple Airlines
Mon 7/2010:01 pm
DSM
- SFO
1 stop19h 24m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$294
This Frontier deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Wed 7/152:19 pm
DSM
- SFO
1 stop12h 04m
Frontier
Deal found 6/16![Frontier logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:20 am
SFO
- DSM
1 stop7h 34m
Multiple Airlines
Mon 8/1710:06 pm
DSM
- SFO
1 stop23h 50m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$303
This Frontier deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Mon 8/172:19 pm
DSM
- SFO
1 stop11h 59m
Frontier
Deal found 6/18![Frontier logo]()
$305
This Orbitz deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am
SFO
- DSM
1 stop5h 56m
Frontier
Mon 10/52:51 pm
DSM
- SFO
1 stop11h 24m
Frontier
Deal found 6/20![Frontier logo]()
$308
Best flights from San Francisco to Des MoinesDiscover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
Discover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:50 am
SFO
- DSM
2 stops9h 55m
Southwest
Wed 8/262:40 pm
DSM
- SFO
2 stops8h 40m
Southwest
Deal found 6/16![Southwest logo]()
$373
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:10 am
SFO
- DSM
1 stop8h 31m
Delta
Thu 9/1710:57 am
DSM
- SFO
1 stop8h 18m
Delta
Deal found 6/18![Delta logo]()
$381
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:45 am
SFO
- DSM
2 stops11h 31m
United Airlines
Wed 8/2611:33 am
DSM
- SFO
1 stop8h 01m
United Airlines
Deal found 6/20![United Airlines logo]()
$468
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:25 am
SFO
- DSM
2 stops8h 20m
Southwest
Sat 11/211:55 pm
DSM
- SFO
1 stop8h 05m
Southwest
Deal found 6/20![Southwest logo]()
$377
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:40 am
SFO
- DSM
1 stop7h 44m
Delta
Sun 11/87:50 pm
DSM
- SFO
1 stop6h 09m
Delta
Deal found 6/20![Delta logo]()
$415
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:50 am
SFO
- DSM
1 stop7h 55m
Southwest
Fri 11/2012:10 pm
DSM
- SFO
1 stop7h 10m
Southwest
Deal found 6/18![Southwest logo]()
$415
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:30 am
SFO
- DSM
2 stops11h 25m
Southwest
Sun 10/186:35 am
DSM
- SFO
2 stops8h 35m
Southwest
Deal found 6/19![Southwest logo]()
$425
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:40 am
SFO
- DSM
1 stop7h 40m
Delta
Thu 11/267:50 pm
DSM
- SFO
1 stop6h 09m
Delta
Deal found 6/16![Delta logo]()
$471
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:00 am
SFO
- DSM
2 stops7h 15m
Southwest
Thu 10/11:50 pm
DSM
- SFO
2 stops8h 30m
Southwest
Deal found 6/17![Southwest logo]()
$434
Last-minute flights from San Francisco to Des MoinesDiscover last-minute flight deals from San Francisco to Des Moines. Data last updated June 21, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Des Moines. Data last updated June 21, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Wed 7/152:19 pm
DSM
- SFO
1 stop12h 04m
Frontier
Deal found 6/16![Frontier logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:23 pm
SFO
- DSM
2 stops36h 36m
Multiple Airlines
Mon 7/2010:01 pm
DSM
- SFO
1 stop19h 24m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$286
This Frontier deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Mon 7/202:19 pm
DSM
- SFO
1 stop12h 04m
Frontier
Deal found 6/19![Frontier logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:00 pm
SFO
- DSM
1 stop22h 11m
Multiple Airlines
Mon 7/2010:01 pm
DSM
- SFO
1 stop19h 24m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$294
This CheapOair deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:39 pm
SFO
- DSM
1 stop13h 55m
Frontier
Mon 7/202:19 pm
DSM
- SFO
1 stop12h 04m
Frontier
Deal found 6/16![Frontier logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/253:43 pm
SFO
- DSM
2 stops29h 04m
Multiple Airlines
Wed 7/291:49 pm
DSM
- SFO
1 stop8h 03m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$332
One-way flights from San Francisco to Des MoinesSearch for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
Search for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
This Priceline deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Deal found 6/17![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:23 pm
SFO
- DSM
2 stops36h 36m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:43 pm
SFO
- DSM
1 stop26h 48m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$131
This CheapOair deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:39 pm
SFO
- DSM
1 stop13h 55m
Frontier
Deal found 6/20![Frontier logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:23 pm
SFO
- DSM
2 stops36h 36m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$172
This Priceline deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Deal found 6/19![Frontier logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:00 pm
SFO
- DSM
1 stop22h 11m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/89:00 pm
SFO
- DSM
1 stop21h 43m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:23 pm
SFO
- DSM
2 stops38h 39m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$181
This Frontier deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Deal found 6/18![Frontier logo]()
$182
Find flight deals from San Francisco to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $242 (Expedia) |
One-way from | $122 (Priceline) |
Popular in | January |
Cheapest in | February |
Average price | $460 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from San Francisco to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Tue 8/25
5:50 am-5:45 pm
2 stops9h 55m
Des Moines
Wed 8/26
2:40 pm-9:20 pm
2 stops8h 40m
$373
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Thu 11/19
10:25 am-8:45 pm
2 stops8h 20m
Des Moines
Sat 11/21
1:55 pm-8:00 pm
1 stop8h 05m
$377
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Mon 9/14
6:10 am-4:41 pm
1 stop8h 31m
Des Moines
Thu 9/17
10:57 am-5:15 pm
1 stop8h 18m
$381
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 11/4
11:40 am-9:24 pm
1 stop7h 44m
Des Moines
Sun 11/8
7:50 pm-11:59 pm
1 stop6h 09m
$415
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 11/18
10:50 am-8:45 pm
1 stop7h 55m
Des Moines
Fri 11/20
12:10 pm-5:20 pm
1 stop7h 10m
$415
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 10/14
7:30 am-8:55 pm
2 stops11h 25m
Des Moines
Sun 10/18
6:35 am-1:10 pm
2 stops8h 35m
$425
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Sun 9/27
6:00 am-3:15 pm
2 stops7h 15m
Des Moines
Thu 10/1
1:50 pm-8:20 pm
2 stops8h 30m
$434
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Mon 8/24
12:45 am-2:16 pm
2 stops11h 31m
Des Moines
Wed 8/26
11:33 am-5:34 pm
1 stop8h 01m
$468
Quickest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 11/20
12:40 am-10:20 am
1 stop7h 40m
Des Moines
Thu 11/26
7:50 pm-11:59 pm
1 stop6h 09m
$471
Cheapest one-way
Quickest one-way
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 7/22
6:00 am-1:34 pm
1 stop5h 34m
$122
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Des Moines in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Francisco with our price prediction graph.
SFO-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Des Moines
What is the cheapest month to book a flight from San Francisco to Des Moines?
Currently, February is the cheapest month in which you can book a flight from San Francisco to Des Moines (average of $280). Flying from San Francisco to Des Moines in January is currently the most expensive (average of $865). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 21, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from San Francisco to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 21, 2026.
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San Francisco and Des Moines flights
Browse other San Francisco and Des Moines flight options. Last updated on June 21, 2026.
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Top 5 airlines flying from San Francisco to Des Moines
Discover the top 5 airlines that operate flights from San Francisco to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$149 | Average$282 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$319 | Average$623 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$341 | Average$554 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$346 | Average$517 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$406 | Average$769 | FlexibilityNo cancel fee | On-time69% |