$108+ Cheap flights from San Francisco to Des Moines (SFO - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — DSM
May 14 — May 211
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Des Moines
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Best
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One-way
Cheapest flights from San Francisco to Des MoinesExplore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 14, 2026.
Explore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 14, 2026.
This Expedia deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Mon 5/112:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 4/11![Frontier logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:33 pm
SFO
- DSM
1 stop27h 38m
Multiple Airlines
Fri 5/298:30 am
DSM
- SFO
1 stop10h 00m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$247
This Frontier deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Fri 5/152:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 4/13![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:33 pm
SFO
- DSM
1 stop27h 38m
Multiple Airlines
Wed 5/272:16 pm
DSM
- SFO
2 stops28h 14m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$252
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:52 pm
SFO
- DSM
1 stop22h 39m
Frontier
Mon 5/112:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 4/9![Frontier logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:33 pm
SFO
- DSM
1 stop27h 38m
Multiple Airlines
Sun 5/3110:26 pm
DSM
- SFO
2 stops25h 29m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:50 pm
SFO
- DSM
1 stop20h 04m
Multiple Airlines
Sun 8/239:50 pm
DSM
- SFO
1 stop24h 06m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:50 pm
SFO
- DSM
1 stop20h 04m
Multiple Airlines
Mon 8/248:38 pm
DSM
- SFO
1 stop15h 49m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:00 am
SFO
- DSM
1 stop29h 31m
Frontier
Wed 5/272:16 pm
DSM
- SFO
2 stops28h 14m
Frontier
Deal found 4/11![Frontier logo]()
$273
Best flights from San Francisco to Des MoinesDiscover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 14, 2026.
Discover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 14, 2026.
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:59 pm
SFO
- DSM
1 stop8h 17m
Delta
Sat 5/97:01 am
DSM
- SFO
1 stop8h 06m
Delta
Deal found 4/9![Delta logo]()
$391
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:30 am
SFO
- DSM
2 stops9h 25m
Southwest
Sat 5/302:00 pm
DSM
- SFO
2 stops9h 20m
Southwest
Deal found 4/13![Southwest logo]()
$409
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:20 pm
SFO
- DSM
2 stops13h 56m
Delta
Wed 5/205:28 pm
DSM
- SFO
1 stop8h 22m
Delta
Deal found 4/9![Delta logo]()
$405
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:45 pm
SFO
- DSM
1 stop6h 10m
Southwest
Sat 5/1612:05 pm
DSM
- SFO
2 stops7h 20m
Southwest
Deal found 4/9![Southwest logo]()
$413
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/411:25 pm
SFO
- DSM
1 stop10h 00m
Southwest
Sat 5/1612:05 pm
DSM
- SFO
1 stop8h 30m
Southwest
Deal found 4/10![Southwest logo]()
$423
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:20 am
SFO
- DSM
1 stop7h 21m
Delta
Sat 5/97:01 am
DSM
- SFO
1 stop6h 16m
Delta
Deal found 4/9![Delta logo]()
$469
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2310:25 am
SFO
- DSM
2 stops9h 15m
Southwest
Mon 6/296:10 am
DSM
- SFO
2 stops7h 50m
Southwest
Deal found 4/12![Southwest logo]()
$435
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:40 am
SFO
- DSM
1 stop5h 40m
Southwest
Sun 5/241:15 pm
DSM
- SFO
2 stops10h 25m
Southwest
Deal found 4/12![Southwest logo]()
$438
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:10 am
SFO
- DSM
2 stops9h 55m
Southwest
Tue 5/123:15 pm
DSM
- SFO
2 stops10h 00m
Southwest
Deal found 4/12![Southwest logo]()
$471
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/411:10 am
SFO
- DSM
2 stops8h 45m
Southwest
Fri 5/86:50 am
DSM
- SFO
2 stops8h 55m
Southwest
Deal found 4/12![Southwest logo]()
$490
Last-minute flights from San Francisco to Des MoinesDiscover last-minute flight deals from San Francisco to Des Moines. Data last updated April 14, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Des Moines. Data last updated April 14, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:33 pm
SFO
- DSM
1 stop27h 38m
Multiple Airlines
Fri 5/298:30 am
DSM
- SFO
1 stop10h 00m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:33 pm
SFO
- DSM
1 stop27h 38m
Multiple Airlines
Wed 5/272:16 pm
DSM
- SFO
2 stops28h 14m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$252
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:52 pm
SFO
- DSM
1 stop22h 39m
Frontier
Mon 5/112:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 4/9![Frontier logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:33 pm
SFO
- DSM
1 stop27h 38m
Multiple Airlines
Sun 5/3110:26 pm
DSM
- SFO
2 stops25h 29m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$264
This Expedia deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Mon 5/112:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 4/11![Frontier logo]()
$230
This Frontier deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Fri 5/152:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 4/13![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:00 am
SFO
- DSM
1 stop29h 31m
Multiple Airlines
Fri 5/298:30 am
DSM
- SFO
1 stop10h 00m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:00 am
SFO
- DSM
1 stop29h 31m
Frontier
Wed 5/272:16 pm
DSM
- SFO
2 stops28h 14m
Frontier
Deal found 4/11![Frontier logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:44 pm
SFO
- DSM
1 stop22h 00m
Multiple Airlines
Mon 6/19:17 pm
DSM
- SFO
2 stops21h 13m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$278
One-way flights from San Francisco to Des MoinesSearch for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 14, 2026.
Search for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 14, 2026.
This eDestinos deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:40 pm
SFO
- DSM
1 stop12h 15m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2310:58 pm
SFO
- DSM
1 stop11h 57m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:18 am
SFO
- DSM
2 stops34h 06m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:26 am
SFO
- DSM
1 stop28h 35m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:26 pm
SFO
- DSM
2 stops38h 05m
Frontier
Deal found 4/10![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:25 pm
SFO
- DSM
2 stops42h 06m
Frontier
Deal found 4/12![Frontier logo]()
$150
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/189:43 pm
SFO
- DSM
1 stop13h 48m
Frontier
Deal found 4/9![Frontier logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:45 pm
SFO
- DSM
2 stops23h 53m
Frontier
Deal found 4/9![Frontier logo]()
$159
Find flight deals from San Francisco to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $230 (Frontier) |
One-way from | $108 (eDestinos) |
Popular in | January |
Cheapest in | February |
Average price | $546 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 14, 2026.
Use the filters below to find and compare flights from San Francisco to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 5/6
11:59 pm-10:16 am
1 stop8h 17m
Des Moines
Sat 5/9
7:01 am-1:07 pm
1 stop8h 06m
$391
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Sat 5/16
6:20 pm-10:16 am
2 stops13h 56m
Des Moines
Wed 5/20
5:28 pm-11:50 pm
1 stop8h 22m
$405
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Thu 5/28
10:30 am-9:55 pm
2 stops9h 25m
Des Moines
Sat 5/30
2:00 pm-9:20 pm
2 stops9h 20m
$409
Quickest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Sat 5/9
12:45 pm-8:55 pm
1 stop6h 10m
Des Moines
Sat 5/16
12:05 pm-5:25 pm
2 stops7h 20m
$413
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Mon 5/4
11:25 pm-11:25 am
1 stop10h 00m
Des Moines
Sat 5/16
12:05 pm-6:35 pm
1 stop8h 30m
$423
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Tue 6/23
10:25 am-9:40 pm
2 stops9h 15m
Des Moines
Mon 6/29
6:10 am-12:00 pm
2 stops7h 50m
$435
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Sat 5/23
5:40 am-1:20 pm
1 stop5h 40m
Des Moines
Sun 5/24
1:15 pm-9:40 pm
2 stops10h 25m
$438
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Sun 5/3
6:20 am-3:41 pm
1 stop7h 21m
Des Moines
Sat 5/9
7:01 am-11:17 am
1 stop6h 16m
$469
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 5/8
11:10 am-11:05 pm
2 stops9h 55m
Des Moines
Tue 5/12
3:15 pm-11:15 pm
2 stops10h 00m
$471
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Mon 5/4
11:10 am-9:55 pm
2 stops8h 45m
Des Moines
Fri 5/8
6:50 am-1:45 pm
2 stops8h 55m
$490
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Des Moines in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Francisco with our price prediction graph.
SFO-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Des Moines
How far ahead should I book a flight from San Francisco to Des Moines?
Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Des Moines. Price data was last updated on April 10, 2026.
The best time to book flights from San Francisco to Des Moines is 81 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from San Francisco to Des Moines?
Currently, September is the cheapest month in which you can book a flight from San Francisco to Des Moines (average of $149). Flying from San Francisco to Des Moines in March is currently the most expensive (average of $440). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 14, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from San Francisco to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
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Boone
West Des Moines
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Top 5 airlines flying from San Francisco to Des Moines
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$149 | Average$280 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$295 | Average$472 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$334 | Average$518 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$346 | Average$448 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$386 | Average$523 | FlexibilityNo cancel fee | On-time69% |