$103+ Cheap flights from San Francisco to Des Moines (SFO - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — DSM
Aug 14 — Aug 211
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Francisco to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Francisco to Des MoinesExplore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 15, 2026.
Explore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:42 am
SFO
- DSM
1 stop7h 24m
Multiple Airlines
Mon 9/149:31 pm
DSM
- SFO
1 stop15h 15m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2911:42 am
SFO
- DSM
1 stop24h 10m
Multiple Airlines
Wed 10/72:42 pm
DSM
- SFO
1 stop29h 07m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:56 pm
SFO
- DSM
1 stop22h 04m
Multiple Airlines
Mon 8/318:54 pm
DSM
- SFO
1 stop25h 02m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:42 am
SFO
- DSM
1 stop7h 24m
Multiple Airlines
Sun 9/139:56 pm
DSM
- SFO
1 stop27h 49m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:00 pm
SFO
- DSM
1 stop13h 59m
Multiple Airlines
Wed 8/122:19 pm
DSM
- SFO
2 stops22h 06m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:07 pm
SFO
- DSM
1 stop20h 47m
Multiple Airlines
Mon 8/1010:06 pm
DSM
- SFO
1 stop14h 19m
Multiple Airlines
Deal found 7/15![Multiple Airlines logo]()
$253
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:45 am
SFO
- DSM
1 stop9h 45m
Southwest
Mon 10/127:10 pm
DSM
- SFO
2 stops7h 30m
Southwest
Deal found 7/10![Southwest logo]()
$262
Best flights from San Francisco to Des MoinesDiscover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 15, 2026.
Discover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 15, 2026.
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:40 pm
SFO
- DSM
1 stop10h 20m
Southwest
Mon 10/192:00 pm
DSM
- SFO
2 stops9h 05m
Southwest
Deal found 7/10![Southwest logo]()
$262
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:55 am
SFO
- DSM
1 stop7h 31m
United Airlines
Wed 9/211:32 am
DSM
- SFO
1 stop9h 17m
United Airlines
Deal found 7/10![United Airlines logo]()
$351
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:50 am
SFO
- DSM
1 stop8h 55m
Southwest
Wed 8/2612:30 pm
DSM
- SFO
2 stops8h 35m
Southwest
Deal found 7/10![Southwest logo]()
$262
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:50 am
SFO
- DSM
2 stops9h 55m
Southwest
Sun 9/67:05 am
DSM
- SFO
1 stop5h 20m
Southwest
Deal found 7/14![Southwest logo]()
$306
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/141:30 pm
SFO
- DSM
1 stop5h 45m
Southwest
Wed 9/167:15 am
DSM
- SFO
2 stops8h 00m
Southwest
Deal found 7/14![Southwest logo]()
$306
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/810:55 am
SFO
- DSM
2 stops9h 00m
Southwest
Mon 10/127:10 pm
DSM
- SFO
2 stops7h 30m
Southwest
Deal found 7/10![Southwest logo]()
$369
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:40 am
SFO
- DSM
2 stops7h 50m
Southwest
Sun 10/46:45 am
DSM
- SFO
2 stops9h 00m
Southwest
Deal found 7/10![Southwest logo]()
$369
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:50 am
SFO
- DSM
1 stop7h 55m
Southwest
Sun 11/86:40 am
DSM
- SFO
1 stop5h 50m
Southwest
Deal found 7/13![Southwest logo]()
$384
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:25 am
SFO
- DSM
2 stops8h 20m
Southwest
Sun 11/221:50 pm
DSM
- SFO
2 stops8h 25m
Southwest
Deal found 7/11![Southwest logo]()
$394
Last-minute flights from San Francisco to Des MoinesDiscover last-minute flight deals from San Francisco to Des Moines. Data last updated July 15, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Des Moines. Data last updated July 15, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:00 pm
SFO
- DSM
1 stop13h 59m
Multiple Airlines
Wed 8/122:19 pm
DSM
- SFO
2 stops22h 06m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:07 pm
SFO
- DSM
1 stop20h 47m
Multiple Airlines
Mon 8/1010:06 pm
DSM
- SFO
1 stop14h 19m
Multiple Airlines
Deal found 7/15![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:15 am
SFO
- DSM
2 stops24h 19m
Multiple Airlines
Sun 8/169:44 pm
DSM
- SFO
1 stop12h 59m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:07 pm
SFO
- DSM
1 stop20h 47m
Multiple Airlines
Sun 8/169:44 pm
DSM
- SFO
1 stop24h 26m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:07 pm
SFO
- DSM
2 stops16h 11m
Multiple Airlines
Mon 8/1710:06 pm
DSM
- SFO
1 stop23h 50m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:56 pm
SFO
- DSM
1 stop22h 04m
Multiple Airlines
Mon 8/318:54 pm
DSM
- SFO
1 stop25h 02m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$225
One-way flights from San Francisco to Des MoinesSearch for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated July 15, 2026.
Search for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated July 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:56 pm
SFO
- DSM
1 stop22h 04m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:42 am
SFO
- DSM
1 stop24h 10m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:00 am
SFO
- DSM
1 stop6h 48m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:56 pm
SFO
- DSM
1 stop22h 04m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:04 pm
SFO
- DSM
2 stops21h 44m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:00 pm
SFO
- DSM
1 stop13h 59m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$124
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:27 am
SFO
- DSM
1 stop7h 28m
American Airlines
Deal found 7/10![American Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/711:42 am
SFO
- DSM
1 stop29h 00m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$128
This CheapOair deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am
SFO
- DSM
1 stop5h 56m
Frontier
Deal found 7/14![Frontier logo]()
$129
This Frontier deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Deal found 7/14![Frontier logo]()
$130
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:10 am
SFO
- DSM
2 stops7h 40m
Southwest
Deal found 7/10![Southwest logo]()
$131
Find flight deals from San Francisco to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $181 (Kiwi.com) |
One-way from | $103 (Kiwi.com) |
Popular in | January |
Cheapest in | February |
Average price | $543 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 15, 2026.
Use the filters below to find and compare flights from San Francisco to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 10/16
11:40 pm-12:00 pm
1 stop10h 20m
Des Moines
Mon 10/19
2:00 pm-9:05 pm
2 stops9h 05m
$262
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 8/19
6:50 am-5:45 pm
1 stop8h 55m
Des Moines
Wed 8/26
12:30 pm-7:05 pm
2 stops8h 35m
$262
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 9/2
5:50 am-5:45 pm
2 stops9h 55m
Des Moines
Sun 9/6
7:05 am-10:25 am
1 stop5h 20m
$306
Quickest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Mon 9/14
1:30 pm-9:15 pm
1 stop5h 45m
Des Moines
Wed 9/16
7:15 am-1:15 pm
2 stops8h 00m
$306
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 8/28
12:55 am-10:26 am
1 stop7h 31m
Des Moines
Wed 9/2
11:32 am-6:49 pm
1 stop9h 17m
$351
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Thu 10/8
10:55 am-9:55 pm
2 stops9h 00m
Des Moines
Mon 10/12
7:10 pm-12:40 am
2 stops7h 30m
$369
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Thu 10/1
8:40 am-6:30 pm
2 stops7h 50m
Des Moines
Sun 10/4
6:45 am-1:45 pm
2 stops9h 00m
$369
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 11/4
10:50 am-8:45 pm
1 stop7h 55m
Des Moines
Sun 11/8
6:40 am-10:30 am
1 stop5h 50m
$384
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 11/18
10:25 am-8:45 pm
2 stops8h 20m
Des Moines
Sun 11/22
1:50 pm-8:15 pm
2 stops8h 25m
$394
Cheapest one-way
Quickest one-way
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 9/30
5:30 am-3:10 pm
1 stop7h 40m
$126
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Des Moines in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Francisco with our price prediction graph.
SFO-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Des Moines
What is the cheapest month to book a flight from San Francisco to Des Moines?
Currently, February is the cheapest month in which you can book a flight from San Francisco to Des Moines (average of $280). Flying from San Francisco to Des Moines in January is currently the most expensive (average of $865). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated July 15, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from San Francisco to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Des Moines flight routes
Flights by cabin class
Other flight options
Other flights from San Francisco
Popular flights
Alternative routes for San Francisco to Des Moines
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 15, 2026.
Search flights from San Francisco to Des Moines by cabin class
Find flights from San Francisco to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and Des Moines flights
Browse other San Francisco and Des Moines flight options. Last updated on July 15, 2026.
Other flights from San Francisco
Browse through other flights departing from San Francisco. Flights are based on user searches made on Cheapflights and were last updated on July 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from San Francisco to Des Moines
Discover the top 5 airlines that operate flights from San Francisco to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$149 | Average$287 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$319 | Average$623 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$345 | Average$566 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$366 | Average$721 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$374 | Average$506 | FlexibilityNo cancel fee | On-time63% |