$127+ Cheap flights from San Francisco to Des Moines (SFO - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/28. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — DSM
Jul 3 — Jul 101
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Des Moines
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Best
Last-minute
One-way
Cheapest flights from San Francisco to Des MoinesExplore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 3, 2026.
Explore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:00 pm
SFO
- DSM
1 stop13h 59m
Multiple Airlines
Mon 8/1010:06 pm
DSM
- SFO
1 stop14h 19m
Multiple Airlines
Deal found 5/29![Multiple Airlines logo]()
$235
This Expedia deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Wed 8/52:19 pm
DSM
- SFO
1 stop11h 59m
Frontier
Deal found 6/2![Frontier logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:00 pm
SFO
- DSM
1 stop13h 59m
Multiple Airlines
Sun 8/309:50 pm
DSM
- SFO
2 stops25h 10m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:00 pm
SFO
- DSM
1 stop13h 59m
Multiple Airlines
Mon 8/310:01 pm
DSM
- SFO
2 stops25h 37m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$277
This Expedia deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Wed 7/152:19 pm
DSM
- SFO
1 stop12h 04m
Frontier
Deal found 6/2![Frontier logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:30 am
SFO
- DSM
1 stop12h 11m
Multiple Airlines
Sun 9/139:56 pm
DSM
- SFO
1 stop27h 49m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$296
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:10 pm
SFO
- DSM
1 stop10h 33m
Delta
Mon 8/172:45 pm
DSM
- SFO
1 stop8h 17m
Delta
Deal found 5/29![Delta logo]()
$300
This CheapOair deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:38 pm
SFO
- DSM
1 stop22h 56m
Frontier
Mon 8/172:19 pm
DSM
- SFO
1 stop23h 19m
Frontier
Deal found 6/2![Frontier logo]()
$307
Best flights from San Francisco to Des MoinesDiscover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 3, 2026.
Discover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 3, 2026.
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:10 pm
SFO
- DSM
1 stop10h 33m
Delta
Mon 8/172:45 pm
DSM
- SFO
1 stop8h 17m
Delta
Deal found 5/29![Delta logo]()
$300
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:20 am
SFO
- DSM
1 stop5h 25m
Southwest
Tue 9/227:15 am
DSM
- SFO
2 stops7h 20m
Southwest
Deal found 6/2![Southwest logo]()
$415
This United Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:40 pm
SFO
- DSM
2 stops17h 52m
United Airlines
Wed 9/25:45 am
DSM
- SFO
1 stop7h 38m
United Airlines
Deal found 5/31![United Airlines logo]()
$475
This Southwest deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:10 am
SFO
- DSM
1 stop8h 00m
Southwest
Sat 8/812:10 pm
DSM
- SFO
2 stops10h 25m
Southwest
Deal found 5/31![Southwest logo]()
$430
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:15 am
SFO
- DSM
1 stop5h 56m
Delta
Sun 11/87:50 pm
DSM
- SFO
1 stop6h 09m
Delta
Deal found 6/2![Delta logo]()
$450
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/612:00 pm
SFO
- DSM
2 stops8h 25m
Southwest
Wed 7/153:45 pm
DSM
- SFO
2 stops9h 35m
Southwest
Deal found 6/2![Southwest logo]()
$441
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:25 am
SFO
- DSM
2 stops8h 20m
Southwest
Sun 11/86:40 am
DSM
- SFO
2 stops8h 25m
Southwest
Deal found 6/1![Southwest logo]()
$441
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2211:00 am
SFO
- DSM
2 stops9h 20m
Southwest
Wed 6/247:00 pm
DSM
- SFO
1 stop5h 25m
Southwest
Deal found 5/30![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/29:25 am
SFO
- DSM
2 stops10h 55m
Southwest
Mon 7/65:10 am
DSM
- SFO
2 stops8h 50m
Southwest
Deal found 5/29![Southwest logo]()
$507
This Southwest deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:30 am
SFO
- DSM
2 stops10h 45m
Southwest
Mon 9/77:00 am
DSM
- SFO
2 stops8h 10m
Southwest
Deal found 5/31![Southwest logo]()
$507
Last-minute flights from San Francisco to Des MoinesDiscover last-minute flight deals from San Francisco to Des Moines. Data last updated June 3, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Des Moines. Data last updated June 3, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Mon 6/292:26 pm
DSM
- SFO
1 stop12h 01m
Frontier
Deal found 6/1![Frontier logo]()
$313
This Expedia deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Wed 7/152:19 pm
DSM
- SFO
1 stop12h 04m
Frontier
Deal found 6/2![Frontier logo]()
$282
This Frontier deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Mon 7/202:19 pm
DSM
- SFO
1 stop12h 04m
Frontier
Deal found 6/1![Frontier logo]()
$316
This Expedia deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Wed 8/52:19 pm
DSM
- SFO
1 stop11h 59m
Frontier
Deal found 6/2![Frontier logo]()
$256
This CheapOair deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:39 pm
SFO
- DSM
1 stop13h 55m
Frontier
Mon 7/202:19 pm
DSM
- SFO
1 stop23h 24m
Frontier
Deal found 6/1![Frontier logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:00 pm
SFO
- DSM
1 stop13h 59m
Multiple Airlines
Sun 8/309:50 pm
DSM
- SFO
2 stops25h 10m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:00 pm
SFO
- DSM
1 stop13h 59m
Multiple Airlines
Mon 8/310:01 pm
DSM
- SFO
2 stops25h 37m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:00 pm
SFO
- DSM
1 stop13h 59m
Multiple Airlines
Thu 7/309:33 pm
DSM
- SFO
1 stop13h 15m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$314
One-way flights from San Francisco to Des MoinesSearch for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 3, 2026.
Search for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2811:15 am
SFO
- DSM
2 stops23h 44m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$127
This deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Deal found 5/31![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3011:24 am
SFO
- DSM
1 stop7h 36m
Multiple Airlines
Deal found 5/29![Multiple Airlines logo]()
$169
This Priceline deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Deal found 6/1![Frontier logo]()
$174
This CheapOair deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:39 pm
SFO
- DSM
1 stop13h 55m
Frontier
Deal found 5/30![Frontier logo]()
$185
This CheapOair deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/129:39 pm
SFO
- DSM
1 stop13h 55m
Frontier
Deal found 5/30![Frontier logo]()
$186
This Frontier deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Deal found 5/31![Frontier logo]()
$195
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:00 pm
SFO
- DSM
1 stop7h 32m
American Airlines
Deal found 5/30![American Airlines logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:11 pm
SFO
- DSM
2 stops18h 23m
Frontier
Deal found 6/3![Frontier logo]()
$205
This CheapOair deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/149:43 pm
SFO
- DSM
1 stop13h 48m
Frontier
Deal found 5/29![Frontier logo]()
$206
Find flight deals from San Francisco to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $235 (Kiwi.com) |
One-way from | $127 (Kiwi.com) |
Popular in | January |
Cheapest in | February |
Average price | $460 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 3, 2026.
Use the filters below to find and compare flights from San Francisco to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Tue 8/11
10:10 pm-10:43 am
1 stop10h 33m
Des Moines
Mon 8/17
2:45 pm-9:02 pm
1 stop8h 17m
$300
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Thu 9/17
6:20 am-1:45 pm
1 stop5h 25m
Des Moines
Tue 9/22
7:15 am-12:35 pm
2 stops7h 20m
$415
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Thu 8/6
5:10 am-3:10 pm
1 stop8h 00m
Des Moines
Sat 8/8
12:10 pm-8:35 pm
2 stops10h 25m
$430
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Mon 7/6
12:00 pm-10:25 pm
2 stops8h 25m
Des Moines
Wed 7/15
3:45 pm-11:20 pm
2 stops9h 35m
$441
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 11/4
10:25 am-8:45 pm
2 stops8h 20m
Des Moines
Sun 11/8
6:40 am-1:05 pm
2 stops8h 25m
$441
Quickest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 11/4
6:15 am-2:11 pm
1 stop5h 56m
Des Moines
Sun 11/8
7:50 pm-11:59 pm
1 stop6h 09m
$450
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Mon 6/22
11:00 am-10:20 pm
2 stops9h 20m
Des Moines
Wed 6/24
7:00 pm-10:25 pm
1 stop5h 25m
$472
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Mon 8/31
4:40 pm-12:32 pm
2 stops17h 52m
Des Moines
Wed 9/2
5:45 am-11:23 am
1 stop7h 38m
$475
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Thu 7/2
9:25 am-10:20 pm
2 stops10h 55m
Des Moines
Mon 7/6
5:10 am-12:00 pm
2 stops8h 50m
$507
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 9/4
8:30 am-9:15 pm
2 stops10h 45m
Des Moines
Mon 9/7
7:00 am-1:10 pm
2 stops8h 10m
$507
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Des Moines in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Francisco with our price prediction graph.
SFO-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Des Moines
How far ahead should I book a flight from San Francisco to Des Moines?
The best time to book flights from San Francisco to Des Moines is 80 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from San Francisco to Des Moines?
Currently, February is the cheapest month in which you can book a flight from San Francisco to Des Moines (average of $280). Flying from San Francisco to Des Moines in January is currently the most expensive (average of $865). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 3, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from San Francisco to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny
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Top 5 airlines flying from San Francisco to Des Moines
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$149 | Average$280 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$319 | Average$623 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$341 | Average$559 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$346 | Average$448 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$406 | Average$721 | FlexibilityNo cancel fee | On-time69% |