$80+ Cheap flights from San Francisco to Des Moines (SFO - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — DSM
apr 28 — maj 51
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Des Moines with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Francisco to Des MoinesExplore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mars 29, 2026.
Explore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mars 29, 2026.
This Frontier deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mån 4/136:00 am
SFO
- DSM
1 stop11h 14m
Frontier
mån 4/202:04 pm
DSM
- SFO
1 stop12h 23m
Frontier
Deal found 3/26![Frontier logo]()
$206
This Frontier deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mån 4/136:00 am
SFO
- DSM
1 stop11h 14m
Frontier
fre 4/172:04 pm
DSM
- SFO
1 stop12h 23m
Frontier
Deal found 3/26![Frontier logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tis 5/2612:52 pm
SFO
- DSM
1 stop22h 39m
Multiple Airlines
sön 5/3110:26 pm
DSM
- SFO
1 stop23h 23m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$236
This CheapOair deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tors 5/2812:52 pm
SFO
- DSM
1 stop22h 39m
Frontier
mån 6/12:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 3/28![Frontier logo]()
$241
This Expedia deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fre 4/106:00 am
SFO
- DSM
1 stop11h 14m
Frontier
fre 4/242:04 pm
DSM
- SFO
1 stop12h 23m
Frontier
Deal found 3/25![Frontier logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons 5/2710:40 pm
SFO
- DSM
1 stop20h 04m
Multiple Airlines
sön 5/3110:26 pm
DSM
- SFO
1 stop23h 23m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$249
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tors 4/99:05 pm
SFO
- DSM
1 stop20h 09m
Frontier
mån 4/138:14 pm
DSM
- SFO
1 stop6h 14m
Frontier
Deal found 3/25![Frontier logo]()
$266
This Frontier deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mån 5/116:00 am
SFO
- DSM
1 stop5h 31m
Frontier
fre 5/152:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 3/27![Frontier logo]()
$270
This CheapOair deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tors 7/169:35 pm
SFO
- DSM
1 stop13h 56m
Frontier
mån 7/202:16 pm
DSM
- SFO
1 stop12h 06m
Frontier
Deal found 3/28![Frontier logo]()
$281
Best flights from San Francisco to Des MoinesDiscover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated mars 29, 2026.
Discover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated mars 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons 4/227:40 pm
SFO
- DSM
1 stop20h 21m
Multiple Airlines
sön 4/262:59 pm
DSM
- SFO
2 stops26h 45m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons 5/68:55 am
SFO
- DSM
1 stop7h 00m
Southwest
lör 5/96:40 am
DSM
- SFO
1 stop5h 45m
Southwest
Deal found 3/27![Southwest logo]()
$399
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fre 5/112:45 am
SFO
- DSM
1 stop7h 52m
United Airlines
ons 5/61:35 pm
DSM
- SFO
1 stop7h 11m
United Airlines
Deal found 3/24![United Airlines logo]()
$431
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tis 5/2611:25 am
SFO
- DSM
2 stops7h 50m
Southwest
tis 6/912:10 pm
DSM
- SFO
1 stop8h 30m
Southwest
Deal found 3/26![Southwest logo]()
$404
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mån 4/2011:25 pm
SFO
- DSM
1 stop10h 00m
Southwest
ons 4/223:15 pm
DSM
- SFO
2 stops9h 30m
Southwest
Deal found 3/26![Southwest logo]()
$419
This Southwest deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tors 5/710:10 am
SFO
- DSM
2 stops9h 45m
Southwest
sön 5/104:20 pm
DSM
- SFO
2 stops10h 00m
Southwest
Deal found 3/29![Southwest logo]()
$465
This Southwest deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tors 4/235:05 am
SFO
- DSM
1 stop8h 25m
Southwest
fre 4/246:50 am
DSM
- SFO
1 stop5h 40m
Southwest
Deal found 3/28![Southwest logo]()
$469
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tis 4/1411:25 am
SFO
- DSM
2 stops7h 50m
Southwest
ons 4/153:15 pm
DSM
- SFO
2 stops8h 55m
Southwest
Deal found 3/26![Southwest logo]()
$490
Last-minute flights from San Francisco to Des MoinesDiscover last-minute flight deals from San Francisco to Des Moines. Data last updated mars 29, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Des Moines. Data last updated mars 29, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tors 4/99:05 pm
SFO
- DSM
1 stop20h 09m
Frontier
mån 4/138:14 pm
DSM
- SFO
1 stop6h 14m
Frontier
Deal found 3/25![Frontier logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tors 4/910:57 pm
SFO
- DSM
1 stop20h 24m
Multiple Airlines
mån 4/138:14 pm
DSM
- SFO
2 stops24h 31m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$336
This Expedia deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fre 4/106:00 am
SFO
- DSM
1 stop11h 14m
Frontier
fre 4/242:04 pm
DSM
- SFO
1 stop12h 23m
Frontier
Deal found 3/25![Frontier logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fre 4/1011:20 am
SFO
- DSM
1 stop8h 01m
Multiple Airlines
fre 4/2410:14 pm
DSM
- SFO
2 stops25h 25m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$330
This Frontier deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mån 4/136:00 am
SFO
- DSM
1 stop11h 14m
Frontier
mån 4/202:04 pm
DSM
- SFO
1 stop12h 23m
Frontier
Deal found 3/26![Frontier logo]()
$206
This Frontier deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mån 4/136:00 am
SFO
- DSM
1 stop11h 14m
Frontier
fre 4/172:04 pm
DSM
- SFO
1 stop12h 23m
Frontier
Deal found 3/26![Frontier logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tors 4/166:00 am
SFO
- DSM
1 stop29h 09m
Multiple Airlines
fre 4/1710:14 pm
DSM
- SFO
1 stop17h 38m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$342
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tors 4/1611:28 pm
SFO
- DSM
1 stop6h 58m
American Airlines
tors 4/237:05 pm
DSM
- SFO
1 stop6h 49m
American Airlines
Deal found 3/26![American Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fre 4/176:00 am
SFO
- DSM
2 stops13h 24m
Multiple Airlines
mån 4/202:04 pm
DSM
- SFO
1 stop12h 23m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fre 4/1711:28 pm
SFO
- DSM
1 stop6h 58m
American Airlines
tis 4/215:00 am
DSM
- SFO
1 stop8h 05m
American Airlines
Deal found 3/25![American Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mån 4/2011:59 pm
SFO
- DSM
1 stop9h 27m
American Airlines
ons 4/225:44 am
DSM
- SFO
1 stop10h 23m
American Airlines
Deal found 3/26![American Airlines logo]()
$331
One-way flights from San Francisco to Des MoinesSearch for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated mars 29, 2026.
Search for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated mars 29, 2026.
This Priceline deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons 5/66:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Deal found 3/27![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tis 5/512:52 pm
SFO
- DSM
1 stop22h 39m
Frontier
Deal found 3/26![Frontier logo]()
$86
This eDestinos deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tis 6/210:40 pm
SFO
- DSM
1 stop12h 15m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$97
This Priceline deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ons 5/206:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Deal found 3/27![Frontier logo]()
$105
This Expedia deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fre 4/106:00 am
SFO
- DSM
1 stop11h 14m
Frontier
Deal found 3/26![Frontier logo]()
$106
This Frontier deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mån 4/136:00 am
SFO
- DSM
1 stop11h 14m
Frontier
Deal found 3/27![Frontier logo]()
$111
This Priceline deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fre 5/86:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Deal found 3/27![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sön 5/39:58 am
SFO
- DSM
2 stops31h 40m
Frontier
Deal found 3/26![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tors 4/1611:56 am
SFO
- DSM
1 stop23h 13m
Frontier
Deal found 3/26![Frontier logo]()
$130
Find flight deals from San Francisco to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated mars 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $206 (Frontier) |
One-way from | $80 (Priceline) |
Popular in | January |
Cheapest in | February |
Average price | $721 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mars 29, 2026.
Use the filters below to find and compare flights from San Francisco to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
ons 4/22
7:40 pm-6:01 pm
1 stop20h 21m
Des Moines
sön 4/26
2:59 pm-3:44 pm
2 stops26h 45m
$368
Quickest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
ons 5/6
8:55 am-5:55 pm
1 stop7h 00m
Des Moines
lör 5/9
6:40 am-10:25 am
1 stop5h 45m
$399
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
tis 5/26
11:25 am-9:15 pm
2 stops7h 50m
Des Moines
tis 6/9
12:10 pm-6:40 pm
1 stop8h 30m
$404
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
mån 4/20
11:25 pm-11:25 am
1 stop10h 00m
Des Moines
ons 4/22
3:15 pm-10:45 pm
2 stops9h 30m
$419
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
fre 5/1
12:45 am-10:37 am
1 stop7h 52m
Des Moines
ons 5/6
1:35 pm-6:46 pm
1 stop7h 11m
$431
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
tors 5/7
10:10 am-9:55 pm
2 stops9h 45m
Des Moines
sön 5/10
4:20 pm-12:20 am
2 stops10h 00m
$465
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
tors 4/23
5:05 am-3:30 pm
1 stop8h 25m
Des Moines
fre 4/24
6:50 am-10:30 am
1 stop5h 40m
$469
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
tis 4/14
11:25 am-9:15 pm
2 stops7h 50m
Des Moines
ons 4/15
3:15 pm-10:10 pm
2 stops8h 55m
$490
Cheapest one-way
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
mån 4/13
6:00 am-7:14 pm
1 stop11h 14m
$106
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
tis 6/2
10:40 pm-12:55 pm
1 stop12h 15m
$114
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Des Moines in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Francisco with our price prediction graph.
SFO-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Des Moines
How far ahead should I book a flight from San Francisco to Des Moines?
Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Des Moines. Price data was last updated on March 13, 2026.
The best time to book flights from San Francisco to Des Moines is 81 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from San Francisco to Des Moines?
Currently, September is the cheapest month in which you can book a flight from San Francisco to Des Moines (average of $149). Flying from San Francisco to Des Moines in March is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated mars 29, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from San Francisco to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Food
7.0
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Food
7.0
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Food
7.0
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Food
7.0
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Food
7.0
Overall
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
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Ankeny
Boone
West Des Moines
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Top 5 airlines flying from San Francisco to Des Moines
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$149 | Average$285 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$263 | Average$472 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$334 | Average$493 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$346 | Average$426 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$386 | Average$528 | FlexibilityNo cancel fee | On-time69% |