$98+ Cheap flights from San Francisco to Des Moines (SFO - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — DSM
Dec 8 — Dec 151
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Des Moines
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Best
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One-way
Cheapest flights from San Francisco to Des MoinesExplore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 8, 2026.
Explore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:06 pm -
1 stop21h 22m
Mon 12/79:18 pm -
1 stop18h 09m
Deal found 11/7![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:30 pm -
1 stop25h 56m
Mon 12/79:18 pm -
1 stop14h 16m
Deal found 11/7![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:06 pm -
1 stop21h 22m
Thu 12/108:39 pm -
1 stop15h 00m
Deal found 11/5![Multiple Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:31 pm -
2 stops20h 11m
Mon 12/149:18 pm -
1 stop14h 16m
Deal found 11/7![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:15 am -
1 stop11h 16m
Sun 1/1010:07 pm -
1 stop17h 15m
Deal found 11/4![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:06 pm -
1 stop21h 22m
Sun 12/63:15 pm -
1 stop22h 11m
Deal found 11/5![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/239:23 pm -
1 stop20h 08m
Sun 1/1010:07 pm -
2 stops14h 57m
Deal found 11/4![Multiple Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/239:23 pm -
1 stop20h 08m
Mon 1/111:57 pm -
1 stop20h 51m
Deal found 11/4![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1711:23 am -
1 stop6h 08m
Mon 1/1111:12 am -
2 stops15h 23m
Deal found 11/4![Multiple Airlines logo]()
$265
Best flights from San Francisco to Des MoinesDiscover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 8, 2026.
Discover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:44 am -
1 stop10h 39m
Sun 1/1010:07 pm -
2 stops20h 47m
Deal found 11/7![Multiple Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/711:59 pm -
1 stop8h 15m
Mon 1/1110:54 am -
1 stop8h 38m
Deal found 11/3![Delta logo]()
$369
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1710:40 am -
2 stops9h 25m
Mon 12/215:40 pm -
2 stops8h 50m
Deal found 11/6![Southwest logo]()
$433
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:15 am -
1 stop7h 58m
Thu 12/108:00 am -
1 stop9h 04m
Deal found 11/4![United Airlines logo]()
$489
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:00 am -
1 stop6h 08m
Wed 12/22:58 pm -
1 stop10h 57m
Deal found 11/3![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/94:35 pm -
2 stops15h 46m
Mon 12/146:53 pm -
2 stops16h 11m
Deal found 11/7![Delta logo]()
$375
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:15 am -
2 stops8h 35m
Thu 12/107:00 am -
2 stops7h 50m
Deal found 11/5![Southwest logo]()
$467
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:40 pm -
1 stop9h 06m
Wed 12/26:41 am -
1 stop6h 26m
Deal found 11/3![Delta logo]()
$400
This Southwest deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:50 am -
2 stops9h 45m
Sun 1/106:55 am -
2 stops9h 15m
Deal found 11/7![Southwest logo]()
$475
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/139:59 pm -
1 stop10h 54m
Mon 12/146:53 pm -
2 stops16h 11m
Deal found 11/7![Delta logo]()
$441
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:40 pm -
1 stop9h 06m
Tue 12/12:58 pm -
1 stop8h 46m
Deal found 11/3![Delta logo]()
$500
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
1 stop6h 08m
Wed 12/22:58 pm -
1 stop9h 50m
Deal found 11/3![Delta logo]()
$503
Last-minute flights from San Francisco to Des MoinesDiscover last-minute flight deals from San Francisco to Des Moines. Data last updated November 8, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Des Moines. Data last updated November 8, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:30 pm -
1 stop25h 56m
Mon 12/79:18 pm -
1 stop14h 16m
Deal found 11/7![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:06 pm -
1 stop21h 22m
Mon 12/79:18 pm -
1 stop18h 09m
Deal found 11/7![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:06 pm -
1 stop21h 22m
Thu 12/108:39 pm -
1 stop15h 00m
Deal found 11/5![Multiple Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:06 pm -
1 stop21h 22m
Sun 12/63:15 pm -
1 stop22h 11m
Deal found 11/5![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:31 pm -
2 stops20h 11m
Mon 12/149:18 pm -
1 stop14h 16m
Deal found 11/7![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:15 am -
1 stop11h 16m
Sun 1/1010:07 pm -
1 stop17h 15m
Deal found 11/4![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1711:23 am -
1 stop6h 08m
Mon 1/111:57 pm -
1 stop20h 51m
Deal found 11/4![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/239:23 pm -
1 stop20h 08m
Sun 1/1010:07 pm -
2 stops14h 57m
Deal found 11/4![Multiple Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/239:23 pm -
1 stop20h 08m
Mon 1/111:57 pm -
1 stop20h 51m
Deal found 11/4![Multiple Airlines logo]()
$264
One-way flights from San Francisco to Des MoinesSearch for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated November 8, 2026.
Search for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated November 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:06 pm -
1 stop21h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Multiple Airlines logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/811:06 am -
1 stop7h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$107
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:26 pm -
1 stop22h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Frontier logo]()
$140
This Trip.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/199:23 pm -
1 stop20h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2212:29 pm -
2 stops54h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:17 pm -
2 stops24h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Frontier logo]()
$154
This Priceline deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1310:34 am -
1 stop7h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Frontier logo]()
$156
Find flight deals from San Francisco to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $215 (Kiwi.com) |
One-way from | $98 (Kiwi.com) |
Popular in | January |
Cheapest in | February |
Average price | $578 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 8, 2026.
Use the filters below to find and compare flights from San Francisco to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Sat 12/19
9:23 pm-7:31 pm
1 stop20h 08m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$145
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Tue 12/22
12:29 pm-9:23 pm
2 stops54h 54m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$147
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Sun 12/13
4:33 pm-2:50 pm
2 stops44h 17m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$177
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Fri 12/25
7:00 am-4:05 pm
1 stop7h 05m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$179
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Wed 12/9
9:59 pm-10:53 am
1 stop10h 54m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$185
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Thu 12/3
12:41 pm-9:25 pm
1 stop6h 44m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$185
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Thu 12/3
10:25 am-8:50 pm
2 stops8h 25m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$190
Quickest round-trip
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Wed 12/9
5:50 am-2:19 pm
1 stop6h 29m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$197
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Fri 12/18
5:25 am-3:05 pm
1 stop7h 40m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$222
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Thu 12/17
8:44 am-9:23 pm
1 stop10h 39m
Des Moines
Sun 1/10
10:07 pm-4:54 pm
2 stops20h 47m
$279
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Des Moines in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Francisco with our price prediction graph.
SFO-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Des Moines
What is the cheapest month to book a flight from San Francisco to Des Moines?
Currently, February is the cheapest month in which you can book a flight from San Francisco to Des Moines (average of $280). Flying from San Francisco to Des Moines in January is currently the most expensive (average of $865). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Des Moines?
Airfare is below average for this route at the moment.
San Francisco to Des Moines flights typically cost between $467 and $822 in January.The cheapest round-trip price found within the last 5 days was $215 on Multiple Airlines (Jan 8-Jan 11).
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated November 8, 2026.
Read reviews from past customers who have flown Southwest,United Airlines, andAmerican Airlines from San Francisco to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Alternative routes for San Francisco to Des Moines
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 8, 2026.
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San Francisco and Des Moines flights
Browse other San Francisco and Des Moines flight options. Last updated on November 8, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Francisco to Des Moines
Discover the top 4 airlines that operate flights from San Francisco to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$329 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$326 | Average$544 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$358 | Average$449 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$406 | Average$893 | FlexibilityNo cancel fee | On-time69% |