$100+ Cheap flights from San Francisco to Des Moines (SFO - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — DSM
Jun 4 — Jun 111
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Des Moines with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Francisco to Des MoinesExplore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.
Explore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.
This Expedia deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Fri 5/292:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 5/3![Frontier logo]()
$210
This Frontier deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Wed 7/152:19 pm
DSM
- SFO
1 stop11h 59m
Frontier
Deal found 5/1![Frontier logo]()
$230
This Expedia deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Fri 5/222:16 pm
DSM
- SFO
1 stop19h 45m
Frontier
Deal found 5/2![Frontier logo]()
$235
This Frontier deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Mon 7/202:19 pm
DSM
- SFO
1 stop11h 59m
Frontier
Deal found 5/4![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:56 pm
SFO
- DSM
1 stop20h 27m
Multiple Airlines
Mon 7/1310:01 pm
DSM
- SFO
1 stop23h 52m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:17 pm
SFO
- DSM
2 stops15h 42m
Multiple Airlines
Mon 7/1310:01 pm
DSM
- SFO
1 stop23h 52m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:36 am
SFO
- DSM
1 stop23h 23m
Multiple Airlines
Mon 6/12:16 pm
DSM
- SFO
2 stops30h 03m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$257
This Frontier deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Fri 5/292:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 5/5![Frontier logo]()
$260
This Frontier deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Mon 6/82:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 5/1![Frontier logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:36 am
SFO
- DSM
1 stop23h 23m
Multiple Airlines
Sun 5/3110:26 pm
DSM
- SFO
2 stops21h 31m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$284
Best flights from San Francisco to Des MoinesDiscover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 5, 2026.
Discover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 5, 2026.
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:15 am
SFO
- DSM
1 stop8h 51m
Delta
Thu 5/287:01 am
DSM
- SFO
1 stop6h 16m
Delta
Deal found 5/3![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3011:05 am
SFO
- DSM
2 stops7h 50m
Southwest
Sat 6/66:55 pm
DSM
- SFO
2 stops7h 40m
Southwest
Deal found 5/1![Southwest logo]()
$409
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:15 am
SFO
- DSM
1 stop8h 51m
Delta
Sat 5/307:01 am
DSM
- SFO
1 stop6h 16m
Delta
Deal found 5/3![Delta logo]()
$459
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:25 am
SFO
- DSM
2 stops7h 50m
Southwest
Fri 5/296:50 am
DSM
- SFO
2 stops8h 55m
Southwest
Deal found 4/30![Southwest logo]()
$464
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:29 am
SFO
- DSM
2 stops21h 47m
Delta
Thu 5/285:28 pm
DSM
- SFO
1 stop8h 22m
Delta
Deal found 5/3![Delta logo]()
$461
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:15 am
SFO
- DSM
1 stop8h 00m
Southwest
Sun 8/235:40 am
DSM
- SFO
1 stop9h 05m
Southwest
Deal found 5/2![Southwest logo]()
$467
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/172:35 pm
SFO
- DSM
1 stop5h 45m
Southwest
Sun 7/194:15 pm
DSM
- SFO
1 stop9h 55m
Southwest
Deal found 5/4![Southwest logo]()
$467
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:40 pm
SFO
- DSM
1 stop6h 05m
Southwest
Sat 9/2612:10 pm
DSM
- SFO
2 stops9h 25m
Southwest
Deal found 5/1![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:40 am
SFO
- DSM
2 stops7h 55m
Southwest
Mon 7/205:10 am
DSM
- SFO
2 stops8h 50m
Southwest
Deal found 5/1![Southwest logo]()
$477
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/109:45 am
SFO
- DSM
2 stops10h 35m
Southwest
Sun 7/126:10 pm
DSM
- SFO
2 stops8h 00m
Southwest
Deal found 5/1![Southwest logo]()
$477
Last-minute flights from San Francisco to Des MoinesDiscover last-minute flight deals from San Francisco to Des Moines. Data last updated May 5, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Des Moines. Data last updated May 5, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Fri 5/222:16 pm
DSM
- SFO
1 stop19h 45m
Frontier
Deal found 5/2![Frontier logo]()
$235
This Frontier deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Wed 5/272:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 5/3![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:36 am
SFO
- DSM
1 stop23h 23m
Multiple Airlines
Mon 6/12:16 pm
DSM
- SFO
2 stops30h 03m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:36 am
SFO
- DSM
1 stop23h 23m
Multiple Airlines
Sun 5/3110:26 pm
DSM
- SFO
2 stops21h 31m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:15 am
SFO
- DSM
2 stops24h 16m
Multiple Airlines
Fri 5/299:36 pm
DSM
- SFO
1 stop13h 13m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$288
This Expedia deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Fri 5/292:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 5/3![Frontier logo]()
$210
This Frontier deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Mon 6/82:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 5/1![Frontier logo]()
$270
This Expedia deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Mon 6/82:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 5/2![Frontier logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:17 pm
SFO
- DSM
2 stops15h 42m
Multiple Airlines
Mon 7/1310:01 pm
DSM
- SFO
1 stop23h 52m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$254
One-way flights from San Francisco to Des MoinesSearch for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated May 5, 2026.
Search for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated May 5, 2026.
This Frontier deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Deal found 5/1![Frontier logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:45 pm
SFO
- DSM
1 stop12h 10m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:15 am
SFO
- DSM
2 stops24h 16m
Frontier
Deal found 5/4![Frontier logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:11 pm
SFO
- DSM
1 stop25h 37m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$123
This Priceline deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Deal found 5/4![Frontier logo]()
$125
This Priceline deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Deal found 5/1![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:16 pm
SFO
- DSM
2 stops18h 15m
Frontier
Deal found 5/1![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:45 pm
SFO
- DSM
1 stop14h 10m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:01 pm
SFO
- DSM
3 stops46h 30m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$145
Find flight deals from San Francisco to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $210 (Expedia) |
One-way from | $100 (Frontier) |
Popular in | January |
Cheapest in | February |
Average price | $519 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from San Francisco to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Mon 5/25
6:15 am-5:06 pm
1 stop8h 51m
Des Moines
Thu 5/28
7:01 am-11:17 am
1 stop6h 16m
$399
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Sat 5/30
11:05 am-8:55 pm
2 stops7h 50m
Des Moines
Sat 6/6
6:55 pm-12:35 am
2 stops7h 40m
$409
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Mon 5/25
6:15 am-5:06 pm
1 stop8h 51m
Des Moines
Sat 5/30
7:01 am-11:17 am
1 stop6h 16m
$459
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 5/27
10:29 am-10:16 am
2 stops21h 47m
Des Moines
Thu 5/28
5:28 pm-11:50 pm
1 stop8h 22m
$461
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Tue 5/26
11:25 am-9:15 pm
2 stops7h 50m
Des Moines
Fri 5/29
6:50 am-1:45 pm
2 stops8h 55m
$464
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 8/21
11:15 am-9:15 pm
1 stop8h 00m
Des Moines
Sun 8/23
5:40 am-12:45 pm
1 stop9h 05m
$467
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 7/17
2:35 pm-10:20 pm
1 stop5h 45m
Des Moines
Sun 7/19
4:15 pm-12:10 am
1 stop9h 55m
$467
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Sat 9/12
12:40 pm-8:45 pm
1 stop6h 05m
Des Moines
Sat 9/26
12:10 pm-7:35 pm
2 stops9h 25m
$472
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Sun 7/19
5:40 am-3:35 pm
2 stops7h 55m
Des Moines
Mon 7/20
5:10 am-12:00 pm
2 stops8h 50m
$477
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 7/10
9:45 am-10:20 pm
2 stops10h 35m
Des Moines
Sun 7/12
6:10 pm-12:10 am
2 stops8h 00m
$477
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Des Moines in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Francisco with our price prediction graph.
SFO-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Des Moines
How far ahead should I book a flight from San Francisco to Des Moines?
The best time to book flights from San Francisco to Des Moines is 80 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from San Francisco to Des Moines?
Currently, February is the cheapest month in which you can book a flight from San Francisco to Des Moines (average of $280). Flying from San Francisco to Des Moines in January is currently the most expensive (average of $865). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated May 5, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from San Francisco to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Overall
7.9
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Overall
7.9
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Overall
7.9
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Overall
7.9
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Overall
7.9
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny
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Top 5 airlines flying from San Francisco to Des Moines
Discover the top 5 airlines that operate flights from San Francisco to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$149 | Average$280 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$319 | Average$623 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$334 | Average$525 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$346 | Average$494 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$386 | Average$531 | FlexibilityNo cancel fee | On-time69% |