$128+ Cheap flights from San Francisco to Des Moines (SFO - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — DSM
Jun 23 — Jun 301
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Des Moines
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Cheapest flights from San Francisco to Des MoinesExplore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 24, 2026.
Explore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 24, 2026.
This Frontier deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Mon 7/202:19 pm
DSM
- SFO
1 stop12h 04m
Frontier
Deal found 5/23![Frontier logo]()
$308
This Frontier deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Mon 6/292:26 pm
DSM
- SFO
1 stop23h 17m
Frontier
Deal found 5/23![Frontier logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:25 am
SFO
- DSM
1 stop13h 10m
Multiple Airlines
Fri 11/1310:25 pm
DSM
- SFO
1 stop14h 04m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$313
This Frontier deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Mon 6/292:26 pm
DSM
- SFO
1 stop12h 01m
Frontier
Deal found 5/21![Frontier logo]()
$317
This Frontier deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Wed 7/82:19 pm
DSM
- SFO
1 stop12h 04m
Frontier
Deal found 5/23![Frontier logo]()
$318
This Frontier deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Wed 7/222:19 pm
DSM
- SFO
1 stop12h 04m
Frontier
Deal found 5/21![Frontier logo]()
$327
This Frontier deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Wed 6/102:16 pm
DSM
- SFO
1 stop12h 11m
Frontier
Deal found 5/19![Frontier logo]()
$329
This Frontier deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am
SFO
- DSM
1 stop5h 18m
Frontier
Mon 10/192:31 pm
DSM
- SFO
1 stop11h 44m
Frontier
Deal found 5/20![Frontier logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1711:20 am
SFO
- DSM
1 stop7h 56m
Multiple Airlines
Sun 8/239:50 pm
DSM
- SFO
2 stops46h 58m
Multiple Airlines
Deal found 5/23![Multiple Airlines logo]()
$343
This Frontier deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Fri 8/212:16 pm
DSM
- SFO
1 stop12h 06m
Frontier
Deal found 5/19![Frontier logo]()
$345
Best flights from San Francisco to Des MoinesDiscover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 24, 2026.
Discover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 24, 2026.
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 am
SFO
- DSM
1 stop6h 05m
Delta
Tue 7/142:25 pm
DSM
- SFO
1 stop10h 24m
Delta
Deal found 5/23![Delta logo]()
$395
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2710:15 am
SFO
- DSM
1 stop5h 55m
Southwest
Sat 7/46:10 am
DSM
- SFO
2 stops7h 20m
Southwest
Deal found 5/20![Southwest logo]()
$472
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/124:18 pm
SFO
- DSM
1 stop5h 26m
United Airlines
Sat 9/269:13 am
DSM
- SFO
1 stop8h 03m
United Airlines
Deal found 5/19![United Airlines logo]()
$521
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1912:35 am
SFO
- DSM
1 stop7h 38m
Delta
Tue 7/2810:54 am
DSM
- SFO
1 stop8h 18m
Delta
Deal found 5/23![Delta logo]()
$431
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/411:45 am
SFO
- DSM
1 stop7h 23m
Delta
Fri 7/106:37 pm
DSM
- SFO
1 stop7h 59m
Delta
Deal found 5/23![Delta logo]()
$467
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:35 am
SFO
- DSM
1 stop7h 51m
United Airlines
Sun 8/236:55 pm
DSM
- SFO
1 stop7h 55m
United Airlines
Deal found 5/19![United Airlines logo]()
$531
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3112:35 am
SFO
- DSM
1 stop7h 38m
Delta
Fri 8/75:56 pm
DSM
- SFO
1 stop7h 51m
Delta
Deal found 5/23![Delta logo]()
$527
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:45 pm
SFO
- DSM
1 stop8h 39m
Delta
Mon 10/193:30 pm
DSM
- SFO
2 stops10h 11m
Delta
Deal found 5/20![Delta logo]()
$573
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:59 pm
SFO
- DSM
2 stops11h 14m
Delta
Mon 7/205:52 pm
DSM
- SFO
1 stop7h 54m
Delta
Deal found 5/21![Delta logo]()
$574
Last-minute flights from San Francisco to Des MoinesDiscover last-minute flight deals from San Francisco to Des Moines. Data last updated May 24, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Des Moines. Data last updated May 24, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Wed 6/102:16 pm
DSM
- SFO
1 stop12h 11m
Frontier
Deal found 5/19![Frontier logo]()
$329
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1512:26 am
SFO
- DSM
1 stop6h 45m
American Airlines
Tue 6/162:24 pm
DSM
- SFO
1 stop6h 42m
American Airlines
Deal found 5/21![American Airlines logo]()
$400
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/163:54 pm
SFO
- DSM
1 stop5h 53m
American Airlines
Wed 6/172:24 pm
DSM
- SFO
1 stop6h 42m
American Airlines
Deal found 5/24![American Airlines logo]()
$395
This Frontier deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Mon 6/292:26 pm
DSM
- SFO
1 stop23h 17m
Frontier
Deal found 5/23![Frontier logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2310:58 pm
SFO
- DSM
1 stop11h 57m
Multiple Airlines
Sun 6/288:36 pm
DSM
- SFO
1 stop14h 15m
Multiple Airlines
Deal found 5/23![Multiple Airlines logo]()
$368
This Frontier deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Mon 6/292:26 pm
DSM
- SFO
1 stop12h 01m
Frontier
Deal found 5/21![Frontier logo]()
$317
This Frontier deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Wed 7/222:19 pm
DSM
- SFO
1 stop12h 04m
Frontier
Deal found 5/21![Frontier logo]()
$327
One-way flights from San Francisco to Des MoinesSearch for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated May 24, 2026.
Search for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated May 24, 2026.
This deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
SFO
- DSM
1 stop5h 34m
Frontier
Deal found 5/19![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:30 am
SFO
- DSM
1 stop12h 36m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:00 pm
SFO
- DSM
2 stops14h 34m
Frontier
Deal found 5/20![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:52 pm
SFO
- DSM
2 stops42h 39m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$159
This Frontier deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Deal found 5/19![Frontier logo]()
$164
This Booking.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/59:39 pm
SFO
- DSM
1 stop13h 55m
Frontier
Deal found 5/23![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:30 am
SFO
- DSM
2 stops30h 01m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$170
This Priceline deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Deal found 5/20![Frontier logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:30 am
SFO
- DSM
1 stop11h 18m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1311:42 am
SFO
- DSM
1 stop7h 24m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:27 pm
SFO
- DSM
2 stops36h 28m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$184
Find flight deals from San Francisco to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $308 (Frontier) |
One-way from | $128 |
Popular in | January |
Cheapest in | February |
Average price | $627 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
Use the filters below to find and compare flights from San Francisco to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 7/8
6:00 am-2:05 pm
1 stop6h 05m
Des Moines
Tue 7/14
2:25 pm-10:49 pm
1 stop10h 24m
$395
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Sun 7/19
12:35 am-10:13 am
1 stop7h 38m
Des Moines
Tue 7/28
10:54 am-5:12 pm
1 stop8h 18m
$431
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Sat 7/4
11:45 am-9:08 pm
1 stop7h 23m
Des Moines
Fri 7/10
6:37 pm-12:36 am
1 stop7h 59m
$467
Quickest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Sat 6/27
10:15 am-6:10 pm
1 stop5h 55m
Des Moines
Sat 7/4
6:10 am-11:30 am
2 stops7h 20m
$472
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Sat 9/12
4:18 pm-11:44 pm
1 stop5h 26m
Des Moines
Sat 9/26
9:13 am-3:16 pm
1 stop8h 03m
$521
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 7/31
12:35 am-10:13 am
1 stop7h 38m
Des Moines
Fri 8/7
5:56 pm-11:47 pm
1 stop7h 51m
$527
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Tue 8/18
12:35 am-10:26 am
1 stop7h 51m
Des Moines
Sun 8/23
6:55 pm-12:50 am
1 stop7h 55m
$531
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 10/16
10:45 pm-9:24 am
1 stop8h 39m
Des Moines
Mon 10/19
3:30 pm-11:41 pm
2 stops10h 11m
$573
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Mon 7/13
8:59 pm-10:13 am
2 stops11h 14m
Des Moines
Mon 7/20
5:52 pm-11:46 pm
1 stop7h 54m
$574
Cheapest one-way
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Tue 7/7
6:00 am-1:34 pm
1 stop29h 34m
$157
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Des Moines in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Francisco with our price prediction graph.
SFO-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Des Moines
How far ahead should I book a flight from San Francisco to Des Moines?
The best time to book flights from San Francisco to Des Moines is 80 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from San Francisco to Des Moines?
Currently, February is the cheapest month in which you can book a flight from San Francisco to Des Moines (average of $280). Flying from San Francisco to Des Moines in January is currently the most expensive (average of $865). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated May 24, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from San Francisco to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Overall
7.9
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Entertainment
7.5
Overall
7.9
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Entertainment
7.5
Overall
7.9
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Entertainment
7.5
Overall
7.9
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Entertainment
7.5
Overall
7.9
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Entertainment
7.5
Overall
7.9
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny
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Top 5 airlines flying from San Francisco to Des Moines
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$149 | Average$280 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$319 | Average$668 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$341 | Average$545 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$346 | Average$517 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$406 | Average$642 | FlexibilityNo cancel fee | On-time69% |