$105+ Cheap flights from San Francisco to Des Moines (SFO - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — DSM
May 22 — May 291
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Des Moines
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Best
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One-way
Cheapest flights from San Francisco to Des MoinesExplore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.
Explore the most affordable flight options available from San Francisco to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.
This Expedia deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
SFO
- DSM
1 stop11h 38m
Frontier
Fri 5/152:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 4/17![Frontier logo]()
$225
This Frontier deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Fri 5/152:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 4/21![Frontier logo]()
$271
This Frontier deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Fri 5/292:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 4/19![Frontier logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:35 pm
SFO
- DSM
1 stop13h 56m
Multiple Airlines
Mon 8/310:01 pm
DSM
- SFO
1 stop14h 26m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:48 pm
SFO
- DSM
2 stops22h 04m
Multiple Airlines
Mon 6/19:17 pm
DSM
- SFO
1 stop15h 13m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:19 am
SFO
- DSM
2 stops33h 52m
Multiple Airlines
Fri 5/153:32 pm
DSM
- SFO
1 stop18h 58m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$327
This Frontier deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Wed 7/12:16 pm
DSM
- SFO
1 stop12h 11m
Frontier
Deal found 4/19![Frontier logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:00 am
SFO
- DSM
1 stop9h 17m
American Airlines
Mon 8/176:48 pm
DSM
- SFO
1 stop6h 15m
American Airlines
Deal found 4/21![American Airlines logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2810:50 pm
SFO
- DSM
1 stop12h 09m
Multiple Airlines
Mon 8/310:01 pm
DSM
- SFO
1 stop14h 26m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$333
This Frontier deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Fri 6/262:16 pm
DSM
- SFO
1 stop12h 11m
Frontier
Deal found 4/19![Frontier logo]()
$335
Best flights from San Francisco to Des MoinesDiscover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2026.
Discover carefully curated flight deals from San Francisco to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2026.
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:20 am
SFO
- DSM
1 stop7h 56m
Delta
Wed 5/135:28 pm
DSM
- SFO
1 stop8h 22m
Delta
Deal found 4/17![Delta logo]()
$413
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:30 am
SFO
- DSM
2 stops8h 45m
Southwest
Thu 5/216:50 am
DSM
- SFO
2 stops7h 45m
Southwest
Deal found 4/16![Southwest logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:52 pm
SFO
- DSM
1 stop22h 39m
Multiple Airlines
Thu 5/218:00 am
DSM
- SFO
1 stop8h 48m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$464
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:10 am
SFO
- DSM
1 stop5h 40m
Southwest
Tue 6/912:10 pm
DSM
- SFO
1 stop8h 30m
Southwest
Deal found 4/19![Southwest logo]()
$467
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/178:35 am
SFO
- DSM
2 stops11h 45m
Southwest
Sat 5/2312:05 pm
DSM
- SFO
2 stops8h 50m
Southwest
Deal found 4/17![Southwest logo]()
$471
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:10 am
SFO
- DSM
2 stops9h 55m
Southwest
Sat 5/1612:05 pm
DSM
- SFO
2 stops9h 15m
Southwest
Deal found 4/20![Southwest logo]()
$488
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:10 am
SFO
- DSM
2 stops9h 55m
Southwest
Wed 5/203:15 pm
DSM
- SFO
2 stops9h 30m
Southwest
Deal found 4/17![Southwest logo]()
$488
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:10 am
SFO
- DSM
2 stops9h 55m
Southwest
Thu 5/216:50 am
DSM
- SFO
2 stops7h 45m
Southwest
Deal found 4/16![Southwest logo]()
$490
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
SFO
- DSM
2 stops10h 35m
Southwest
Fri 5/1512:25 pm
DSM
- SFO
2 stops8h 00m
Southwest
Deal found 4/17![Southwest logo]()
$519
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:25 pm
SFO
- DSM
1 stop10h 05m
Southwest
Sun 5/178:40 pm
DSM
- SFO
1 stop5h 40m
Southwest
Deal found 4/20![Southwest logo]()
$559
Last-minute flights from San Francisco to Des MoinesDiscover last-minute flight deals from San Francisco to Des Moines. Data last updated April 22, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Des Moines. Data last updated April 22, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
SFO
- DSM
1 stop11h 38m
Frontier
Fri 5/152:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 4/17![Frontier logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/59:26 pm
SFO
- DSM
2 stops42h 35m
Multiple Airlines
Mon 5/1110:00 am
DSM
- SFO
1 stop6h 48m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:19 am
SFO
- DSM
2 stops33h 52m
Multiple Airlines
Fri 5/153:32 pm
DSM
- SFO
1 stop18h 58m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:40 pm
SFO
- DSM
1 stop20h 31m
Multiple Airlines
Mon 5/112:16 pm
DSM
- SFO
2 stops22h 25m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$351
This Frontier deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Fri 5/152:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 4/21![Frontier logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:26 am
SFO
- DSM
1 stop23h 33m
Multiple Airlines
Tue 5/264:25 pm
DSM
- SFO
2 stops42h 24m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:48 pm
SFO
- DSM
2 stops22h 04m
Multiple Airlines
Mon 6/19:17 pm
DSM
- SFO
1 stop15h 13m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$311
This Frontier deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Fri 5/292:16 pm
DSM
- SFO
1 stop12h 07m
Frontier
Deal found 4/19![Frontier logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:44 pm
SFO
- DSM
1 stop22h 00m
Multiple Airlines
Sun 5/3110:26 pm
DSM
- SFO
2 stops25h 29m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$360
One-way flights from San Francisco to Des MoinesSearch for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 22, 2026.
Search for one-way flight options from San Francisco to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 22, 2026.
This Frontier deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Deal found 4/21![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:26 am
SFO
- DSM
1 stop23h 33m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$112
This Trip.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:52 pm
SFO
- DSM
1 stop22h 39m
Frontier
Deal found 4/17![Frontier logo]()
$136
This eDestinos deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:40 pm
SFO
- DSM
1 stop12h 15m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
SFO
- DSM
2 stops29h 20m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$138
This Frontier deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
SFO
- DSM
1 stop5h 31m
Frontier
Deal found 4/17![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:48 pm
SFO
- DSM
2 stops22h 04m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$174
Find flight deals from San Francisco to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $225 (Expedia) |
One-way from | $105 (Frontier) |
Popular in | January |
Cheapest in | February |
Average price | $546 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from San Francisco to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 5/6
12:20 am-10:16 am
1 stop7h 56m
Des Moines
Wed 5/13
5:28 pm-11:50 pm
1 stop8h 22m
$413
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Wed 5/13
10:30 am-9:15 pm
2 stops8h 45m
Des Moines
Thu 5/21
6:50 am-12:35 pm
2 stops7h 45m
$435
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Thu 5/14
12:52 pm-1:31 pm
1 stop22h 39m
Des Moines
Thu 5/21
8:00 am-2:48 pm
1 stop8h 48m
$464
Quickest round-trip
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 6/5
5:10 am-12:50 pm
1 stop5h 40m
Des Moines
Tue 6/9
12:10 pm-6:40 pm
1 stop8h 30m
$467
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Sun 5/17
8:35 am-10:20 pm
2 stops11h 45m
Des Moines
Sat 5/23
12:05 pm-6:55 pm
2 stops8h 50m
$471
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 5/15
11:10 am-11:05 pm
2 stops9h 55m
Des Moines
Sat 5/16
12:05 pm-7:20 pm
2 stops9h 15m
$488
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 5/15
11:10 am-11:05 pm
2 stops9h 55m
Des Moines
Wed 5/20
3:15 pm-10:45 pm
2 stops9h 30m
$488
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 5/15
11:10 am-11:05 pm
2 stops9h 55m
Des Moines
Thu 5/21
6:50 am-12:35 pm
2 stops7h 45m
$490
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Thu 5/7
6:00 am-6:35 pm
2 stops10h 35m
Des Moines
Fri 5/15
12:25 pm-6:25 pm
2 stops8h 00m
$519
San FranciscoDes Moines
SFO - DSM
SFODSM
San Francisco
Fri 5/15
11:25 pm-11:30 am
1 stop10h 05m
Des Moines
Sun 5/17
8:40 pm-12:20 am
1 stop5h 40m
$559
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Des Moines in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Francisco with our price prediction graph.
SFO-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Des Moines
How far ahead should I book a flight from San Francisco to Des Moines?
Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Des Moines. Price data was last updated on April 17, 2026.
The best time to book flights from San Francisco to Des Moines is 81 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from San Francisco to Des Moines?
Currently, February is the cheapest month in which you can book a flight from San Francisco to Des Moines (average of $280). Flying from San Francisco to Des Moines in January is currently the most expensive (average of $865). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 22, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from San Francisco to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny
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Top 5 airlines flying from San Francisco to Des Moines
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$149 | Average$280 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$295 | Average$503 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$334 | Average$518 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$346 | Average$476 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$386 | Average$531 | FlexibilityNo cancel fee | On-time69% |