$89+ Cheap flights from San Diego to Des Moines (SAN - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — DSM
Nov 23 — Nov 301
1 adult, Economy
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Find cheap flights from San Diego to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Diego to Des Moines are usually found in July or May, booked 84 days in advance, depart on a Friday or Wednesday and return on a Monday
Cheap flight deals from San Diego to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 24, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $177 (American Airlines) |
One-way from | $89 (American Airlines) |
Popular in | February |
Cheapest in | July |
Average price | $373 |
Find flight deals from San Diego to Des Moines
Cheapest flights from San Diego to Des MoinesExplore the most affordable flight options available from San Diego to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2025.
Explore the most affordable flight options available from San Diego to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2025.
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/101:25 pmSAN - DSM
1 stop8h 23mAmerican Airlines
Wed 12/175:21 amDSM - SAN
1 stop8h 36mAmerican Airlines
Deal found 10/23![American Airlines logo]()
$177
This Mytrip deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:00 pmSAN - DSM
1 stop17h 47mFrontier
Mon 11/102:32 pmDSM - SAN
1 stop11h 18mFrontier
Deal found 10/22![Frontier logo]()
$183
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1112:43 pmSAN - DSM
1 stop8h 05mAmerican Airlines
Tue 12/163:38 pmDSM - SAN
1 stop8h 43mAmerican Airlines
Deal found 10/23![American Airlines logo]()
$188
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:25 amSAN - DSM
1 stop6h 15mAmerican Airlines
Mon 12/155:10 amDSM - SAN
1 stop5h 37mAmerican Airlines
Deal found 10/23![American Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:34 amSAN - DSM
2 stops37h 02mMultiple Airlines
Mon 12/87:58 pmDSM - SAN
1 stop6h 01mMultiple Airlines
Deal found 10/23![Multiple Airlines logo]()
$205
This Gotogate deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:28 pmSAN - DSM
1 stop19h 19mFrontier
Mon 11/32:32 pmDSM - SAN
1 stop23h 35mFrontier
Deal found 10/22![Frontier logo]()
$208
This Gotogate deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:00 pmSAN - DSM
1 stop17h 47mFrontier
Sun 11/22:32 pmDSM - SAN
1 stop22h 45mFrontier
Deal found 10/22![Frontier logo]()
$251
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:20 amSAN - DSM
1 stop8h 43mDelta
Wed 12/1710:20 amDSM - SAN
1 stop10h 01mDelta
Deal found 10/24![Delta logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:34 pmSAN - DSM
1 stop26h 02mMultiple Airlines
Mon 11/32:32 pmDSM - SAN
2 stops31h 52mMultiple Airlines
Deal found 10/22![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:34 pmSAN - DSM
1 stop26h 02mMultiple Airlines
Sun 11/25:34 pmDSM - SAN
2 stops19h 43mMultiple Airlines
Deal found 10/22![Multiple Airlines logo]()
$273
This Mytrip deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:00 pmSAN - DSM
1 stop17h 47mFrontier
Sun 11/92:32 pmDSM - SAN
1 stop22h 45mFrontier
Deal found 10/22![Frontier logo]()
$275
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 24, 2025.
Use the filters below to find and compare flights from San Diego to Des Moines that are best for you.
Fly from
San Diego
Fly to
Des Moines
Route
Depart
Return
Price
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Wed 12/10
4:25 pm-11:59 pm
1 stop5h 34m
Des Moines
Wed 12/17
5:21 am-8:47 am
1 stop5h 26m
$177
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Thu 12/11
6:15 am-4:19 pm
1 stop8h 04m
Des Moines
Tue 12/16
5:00 am-9:54 am
1 stop6h 54m
$188
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Thu 12/11
6:20 am-5:03 pm
1 stop8h 43m
Des Moines
Mon 12/15
2:59 pm-8:42 pm
1 stop7h 43m
$257
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Thu 12/11
11:36 am-8:46 pm
1 stop7h 10m
Des Moines
Tue 12/16
6:17 am-2:12 pm
1 stop9h 55m
$257
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Tue 2/24
6:42 am-2:26 pm
1 stop5h 44m
Des Moines
Wed 2/25
2:06 pm-8:21 pm
1 stop8h 15m
$257
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Tue 2/24
6:20 am-4:30 pm
1 stop8h 10m
Des Moines
Wed 2/25
10:15 am-6:03 pm
1 stop9h 48m
$257
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Wed 11/12
6:41 am-1:56 pm
1 stop29h 15m
Des Moines
Thu 11/13
5:49 pm-3:14 pm
1 stop23h 25m
$287
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Thu 11/6
3:59 pm-10:40 pm
1 stop28h 41m
Des Moines
Sun 11/9
2:17 pm-10:49 am
2 stops22h 32m
$320
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Tue 1/13
6:20 am-3:14 pm
1 stop6h 54m
$89
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Wed 12/17
4:25 pm-11:59 pm
1 stop5h 34m
$89
Showing 1-10 of 19 results
Compare providers for flights from San Diego to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Des Moines in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Des Moines
How far ahead should I book a flight from San Diego to Des Moines?
Use this chart to determine the optimal time to book a round-trip flight from San Diego to Des Moines. Price data was last updated on October 17, 2025.
Booking 80 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Des Moines. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Des Moines?
Currently, July is the cheapest month in which you can book a flight from San Diego to Des Moines (average of $75). Flying from San Diego to Des Moines in August is currently the most expensive (average of $172). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to DSM?
Find hourly flight availability from San Diego to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 24, 2025.
One of the essential ways to save on airfare from San Diego to Des Moines is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 69% on airfare.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 24, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from San Diego to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Overall
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Overall
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Overall
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Overall
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Overall
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Related info for your journey
Find useful and relevant information for your journey from San Diego to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsJohnston
Altoona
Boone
Ames
West Des Moines
Ankeny
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Alternative routes for San Diego to Des Moines
See prices for flight routes from nearby airports that may be better suited for you.
Top 6 airlines flying from San Diego to Des Moines
Discover the top 6 airlines that operate flights from San Diego to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 24, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$75 | Average$171 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$148 | Average$364 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$158 | Average$250 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$286 | Average$443 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$286 | Average$403 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$306 | Average$489 | FlexibilityNo cancel fee | On-time63% |