$112+ Cheap flights from San Diego to Des Moines (SAN - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — DSM
Jan 4 — Jan 111
1 adult, Economy
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Find cheap flights from San Diego to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Diego to Des Moines are usually found in November or July, booked 84 days in advance, depart on a Friday or Wednesday and return on a Monday
Cheap flight deals from San Diego to Des Moines
Cheapest flights from San Diego to Des MoinesExplore the most affordable flight options available from San Diego to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 5, 2025.
Explore the most affordable flight options available from San Diego to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 5, 2025.
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:21 pmSAN - DSM
1 stop18h 10mMultiple Airlines
Mon 1/512:46 pmDSM - SAN
2 stops25h 22mMultiple Airlines
Deal found 12/2![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:25 amSAN - DSM
1 stop11h 19mMultiple Airlines
Mon 1/512:46 pmDSM - SAN
2 stops25h 22mMultiple Airlines
Deal found 12/2![Multiple Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:06 pmSAN - DSM
1 stop20h 24mMultiple Airlines
Mon 1/512:46 pmDSM - SAN
2 stops25h 22mMultiple Airlines
Deal found 12/2![Multiple Airlines logo]()
$267
This Frontier deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:25 amSAN - DSM
1 stop11h 19mFrontier
Fri 1/28:29 pmDSM - SAN
1 stop5h 30mFrontier
Deal found 12/2![Frontier logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:21 pmSAN - DSM
1 stop13h 39mMultiple Airlines
Mon 1/512:46 pmDSM - SAN
2 stops25h 22mMultiple Airlines
Deal found 12/2![Multiple Airlines logo]()
$277
This Frontier deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:25 amSAN - DSM
1 stop11h 19mFrontier
Mon 1/58:29 pmDSM - SAN
1 stop5h 30mFrontier
Deal found 12/2![Frontier logo]()
$278
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:52 amSAN - DSM
1 stop6h 10mDelta
Tue 1/612:04 pmDSM - SAN
1 stop8h 54mDelta
Deal found 12/2![Delta logo]()
$281
This Frontier deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:25 amSAN - DSM
1 stop5h 15mFrontier
Mon 1/58:29 pmDSM - SAN
1 stop5h 30mFrontier
Deal found 12/2![Frontier logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/301:06 pmSAN - DSM
1 stop23h 04mMultiple Airlines
Mon 1/512:46 pmDSM - SAN
2 stops25h 22mMultiple Airlines
Deal found 12/2![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/281:06 pmSAN - DSM
1 stop20h 50mMultiple Airlines
Mon 1/512:46 pmDSM - SAN
2 stops25h 22mMultiple Airlines
Deal found 12/2![Multiple Airlines logo]()
$294
Find flight deals from San Diego to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 5, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $188 (Kiwi.com) |
One-way from | $112 (American Airlines) |
Popular in | February |
Cheapest in | November |
Average price | $486 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 5, 2025.
Use the filters below to find and compare flights from San Diego to Des Moines that are best for you.
Fly from
San Diego
Fly to
Des Moines
Route
Depart
Return
Price
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Fri 1/9
6:36 am-7:22 pm
1 stop10h 46m
Des Moines
Sun 1/11
4:30 pm-12:14 pm
2 stops21h 44m
$188
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Fri 1/16
6:25 am-7:23 pm
1 stop10h 58m
Des Moines
Sun 1/18
4:30 pm-7:31 pm
1 stop29h 01m
$193
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Fri 1/23
4:00 pm-11:58 pm
1 stop5h 58m
Des Moines
Tue 1/27
5:01 pm-10:26 pm
1 stop7h 25m
$222
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Fri 1/23
4:10 pm-11:44 pm
1 stop5h 34m
Des Moines
Tue 1/27
5:30 am-2:52 pm
2 stops11h 22m
$252
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Fri 12/26
6:25 am-7:44 pm
1 stop11h 19m
Des Moines
Fri 1/2
8:29 pm-11:59 pm
1 stop5h 30m
$268
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Thu 5/28
8:50 am-4:14 pm
1 stop5h 24m
Des Moines
Sat 5/30
5:03 pm-9:08 pm
1 stop6h 05m
$271
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Mon 12/29
7:21 pm-3:31 pm
1 stop18h 10m
Des Moines
Sun 1/4
4:30 pm-6:26 pm
1 stop27h 56m
$277
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Thu 12/25
11:52 am-8:02 pm
1 stop6h 10m
Des Moines
Tue 1/6
12:04 pm-6:58 pm
1 stop8h 54m
$281
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Thu 1/8
12:11 pm-10:30 pm
1 stop8h 19m
Des Moines
Mon 1/12
3:35 pm-10:33 pm
1 stop8h 58m
$303
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Thu 2/5
10:09 am-5:33 pm
1 stop5h 24m
$112
Showing 1-10 of 16 results
Compare providers for flights from San Diego to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Des Moines in December.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Diego-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Diego-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Des Moines
How far ahead should I book a flight from San Diego to Des Moines?
Use this chart to determine the optimal time to book a round-trip flight from San Diego to Des Moines. Price data was last updated on November 28, 2025.
Booking 80 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Des Moines. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Des Moines?
Currently, July is the cheapest month in which you can book a flight from San Diego to Des Moines (average of $75). Flying from San Diego to Des Moines in August is currently the most expensive (average of $172). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to DSM?
Find hourly flight availability from San Diego to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 5, 2025.
One of the essential ways to save on airfare from San Diego to Des Moines is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 69% on airfare.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated December 5, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from San Diego to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsJohnston
Altoona
Boone
Ames
West Des Moines
Ankeny
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Alternative routes for San Diego to Des Moines
See prices for flight routes from nearby airports that may be better suited for you.
Top 6 airlines flying from San Diego to Des Moines
Discover the top 6 airlines that operate flights from San Diego to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 5, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$75 | Average$171 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$148 | Average$329 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$162 | Average$262 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$286 | Average$496 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$286 | Average$451 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$286 | Average$407 | FlexibilityNo cancel fee | On-time71% |