$42+ Cheap flights from Jacksonville to Des Moines (JAX - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — DSM
May 16 — May 231
Round-trip
1 adult, Economy
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Find cheap flights from Jacksonville to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Jacksonville to Des Moines
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Best
Last-minute
One-way
Cheapest flights from Jacksonville to Des MoinesExplore the most affordable flight options available from Jacksonville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 16, 2026.
Explore the most affordable flight options available from Jacksonville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/29:32 pm
JAX
- DSM
Nonstop2h 35m
Allegiant Air
Sun 7/53:59 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Deal found 4/12![Allegiant Air logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:32 pm
JAX
- DSM
Nonstop2h 35m
Allegiant Air
Sun 7/263:59 pm
DSM
- JAX
Nonstop2h 34m
Allegiant Air
Deal found 4/13![Allegiant Air logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:32 pm
JAX
- DSM
Nonstop2h 35m
Multiple Airlines
Sun 7/264:57 pm
DSM
- JAX
2 stops22h 17m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/210:33 pm
JAX
- DSM
1 stop18h 17m
Multiple Airlines
Sun 7/53:59 pm
DSM
- JAX
Nonstop2h 34m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:28 pm
JAX
- DSM
3 stops40h 35m
Multiple Airlines
Thu 7/95:08 pm
DSM
- JAX
Nonstop2h 34m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:30 pm
JAX
- DSM
3 stops53h 28m
Multiple Airlines
Thu 6/185:02 pm
DSM
- JAX
Nonstop2h 29m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:32 pm
JAX
- DSM
Nonstop2h 35m
Multiple Airlines
Sat 7/253:20 pm
DSM
- JAX
2 stops47h 54m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:32 pm
JAX
- DSM
2 stops37h 05m
Allegiant Air
Thu 6/185:02 pm
DSM
- JAX
Nonstop2h 29m
Allegiant Air
Deal found 4/13![Allegiant Air logo]()
$317
Best flights from Jacksonville to Des MoinesDiscover carefully curated flight deals from Jacksonville to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 16, 2026.
Discover carefully curated flight deals from Jacksonville to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/29:32 pm
JAX
- DSM
Nonstop2h 35m
Multiple Airlines
Sun 7/54:57 pm
DSM
- JAX
2 stops22h 17m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$250
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:35 am
JAX
- DSM
2 stops10h 40m
United Airlines
Tue 5/1211:40 am
DSM
- JAX
1 stop5h 05m
United Airlines
Deal found 4/14![United Airlines logo]()
$356
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:10 am
JAX
- DSM
1 stop9h 00m
Southwest
Wed 5/63:15 pm
DSM
- JAX
1 stop5h 00m
Southwest
Deal found 4/10![Southwest logo]()
$378
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:45 am
JAX
- DSM
1 stop6h 17m
Delta
Mon 5/112:33 pm
DSM
- JAX
1 stop5h 03m
Delta
Deal found 4/14![Delta logo]()
$396
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:17 pm
JAX
- DSM
1 stop5h 40m
American Airlines
Mon 5/254:48 pm
DSM
- JAX
1 stop5h 54m
American Airlines
Deal found 4/10![American Airlines logo]()
$416
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:35 am
JAX
- DSM
2 stops14h 20m
Southwest
Tue 5/263:15 pm
DSM
- JAX
1 stop5h 00m
Southwest
Deal found 4/12![Southwest logo]()
$383
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:14 pm
JAX
- DSM
1 stop7h 21m
United Airlines
Sat 6/271:05 pm
DSM
- JAX
1 stop7h 54m
United Airlines
Deal found 4/13![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:35 am
JAX
- DSM
2 stops14h 20m
Southwest
Wed 5/275:30 am
DSM
- JAX
2 stops10h 50m
Southwest
Deal found 4/11![Southwest logo]()
$388
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:00 am
JAX
- DSM
2 stops8h 20m
American Airlines
Sat 5/23:20 pm
DSM
- JAX
1 stop7h 24m
American Airlines
Deal found 4/10![American Airlines logo]()
$443
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:30 pm
JAX
- DSM
1 stop4h 12m
Delta
Mon 8/245:45 am
DSM
- JAX
1 stop6h 53m
Delta
Deal found 4/12![Delta logo]()
$445
Last-minute flights from Jacksonville to Des MoinesDiscover last-minute flight deals from Jacksonville to Des Moines. Data last updated April 16, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to Des Moines. Data last updated April 16, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:45 am
JAX
- DSM
1 stop5h 41m
American Airlines
Sat 5/25:01 pm
DSM
- JAX
1 stop5h 30m
American Airlines
Deal found 4/10![American Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:10 am
JAX
- DSM
1 stop9h 00m
Southwest
Wed 5/63:15 pm
DSM
- JAX
1 stop5h 00m
Southwest
Deal found 4/13![Southwest logo]()
$378
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:39 pm
JAX
- DSM
1 stop5h 55m
Delta
Wed 5/1310:26 am
DSM
- JAX
1 stop5h 53m
Delta
Deal found 4/14![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:35 am
JAX
- DSM
1 stop6h 20m
Delta
Mon 5/116:41 pm
DSM
- JAX
1 stop4h 42m
Delta
Deal found 4/14![Delta logo]()
$396
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:00 pm
JAX
- DSM
1 stop7h 24m
United Airlines
Tue 5/125:30 am
DSM
- JAX
1 stop8h 47m
United Airlines
Deal found 4/14![United Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:00 am
JAX
- DSM
2 stops8h 46m
American Airlines
Wed 5/135:44 am
DSM
- JAX
2 stops8h 22m
American Airlines
Deal found 4/15![American Airlines logo]()
$361
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:15 pm
JAX
- DSM
2 stops9h 55m
Southwest
Tue 5/125:30 am
DSM
- JAX
2 stops10h 50m
Southwest
Deal found 4/14![Southwest logo]()
$367
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:46 pm
JAX
- DSM
1 stop6h 53m
United Airlines
Mon 5/116:15 am
DSM
- JAX
1 stop7h 23m
United Airlines
Deal found 4/15![United Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:35 am
JAX
- DSM
2 stops14h 20m
Southwest
Tue 5/265:30 am
DSM
- JAX
2 stops6h 45m
Southwest
Deal found 4/12![Southwest logo]()
$388
One-way flights from Jacksonville to Des MoinesSearch for one-way flight options from Jacksonville to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 16, 2026.
Search for one-way flight options from Jacksonville to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:21 pm
JAX
- DSM
Nonstop2h 37m
Allegiant Air
Deal found 4/11![Allegiant Air logo]()
$42
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:30 pm
JAX
- DSM
3 stops29h 01m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:03 pm
JAX
- DSM
2 stops41h 43m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:30 pm
JAX
- DSM
2 stops21h 45m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:30 pm
JAX
- DSM
2 stops20h 16m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$162
This American Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/54:28 pm
JAX
- DSM
1 stop7h 48m
American Airlines
Deal found 4/12![American Airlines logo]()
$176
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:35 am
JAX
- DSM
1 stop6h 20m
Delta
Deal found 4/14![Delta logo]()
$185
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:05 am
JAX
- DSM
1 stop5h 03m
Delta
Deal found 4/12![Delta logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:30 pm
JAX
- DSM
3 stops29h 01m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:36 pm
JAX
- DSM
2 stops27h 57m
Allegiant Air
Deal found 4/12![Allegiant Air logo]()
$191
Find flight deals from Jacksonville to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $127 (Kiwi.com) |
One-way from | $42 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $416 |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 16, 2026.
Use the filters below to find and compare flights from Jacksonville to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
Thu 7/2
9:32 pm-11:07 pm
Nonstop2h 35m
Des Moines
Sun 7/5
4:57 pm-4:14 pm
2 stops22h 17m
$250
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
Wed 5/6
6:35 am-4:15 pm
2 stops10h 40m
Des Moines
Tue 5/12
11:40 am-5:45 pm
1 stop5h 05m
$356
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
Mon 5/4
5:10 am-1:10 pm
1 stop9h 00m
Des Moines
Wed 5/6
3:15 pm-9:15 pm
1 stop5h 00m
$378
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
Sat 5/23
7:35 am-8:55 pm
2 stops14h 20m
Des Moines
Tue 5/26
3:15 pm-9:15 pm
1 stop5h 00m
$383
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
Sat 5/23
7:35 am-8:55 pm
2 stops14h 20m
Des Moines
Wed 5/27
5:30 am-5:20 pm
2 stops10h 50m
$388
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
Wed 6/24
4:14 pm-10:35 pm
1 stop7h 21m
Des Moines
Sat 6/27
1:05 pm-9:59 pm
1 stop7h 54m
$389
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
Wed 5/6
11:45 am-5:02 pm
1 stop6h 17m
Des Moines
Mon 5/11
2:33 pm-8:36 pm
1 stop5h 03m
$396
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
Sat 5/23
7:17 pm-11:57 pm
1 stop5h 40m
Des Moines
Mon 5/25
4:48 pm-11:42 pm
1 stop5h 54m
$416
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
Sat 5/2
6:00 am-1:20 pm
2 stops8h 20m
Des Moines
Sat 5/2
3:20 pm-11:44 pm
1 stop7h 24m
$443
Quickest round-trip
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
Fri 8/21
2:30 pm-5:42 pm
1 stop4h 12m
Des Moines
Mon 8/24
5:45 am-1:38 pm
1 stop6h 53m
$445
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Jacksonville to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to Des Moines in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Jacksonville-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Jacksonville-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Jacksonville-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Jacksonville-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Jacksonville to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Jacksonville with our price prediction graph.
JAX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to Des Moines
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 16, 2026.
Read through reviews of airlines operating flights from Jacksonville to Des Moines, such as Delta,United Airlines, andAllegiant Air. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.9
Comfort
7.9
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Overall
7.9
Comfort
7.9
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Overall
7.9
Comfort
7.9
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Overall
7.9
Comfort
7.9
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Overall
7.9
Comfort
7.9
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
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Find useful and relevant information for your journey from Jacksonville to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny
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Top 4 airlines flying from Jacksonville to Des Moines
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$82 | Average$92 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$130 | Average$454 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$286 | Average$385 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$351 | Average$426 | FlexibilityNo cancel fee | On-time69% |