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Des Moines

$141+ Cheap flights from Jacksonville to Des Moines (JAX - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — DSM
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Jacksonville to Des Moines

Cheapest flights from Jacksonville to Des Moines
Explore the most affordable flight options available from Jacksonville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/244:55 pm
JAX
-
DSM
1 stop5h 46m
United Airlines
Tue 3/38:00 am
DSM
-
JAX
1 stop6h 26m
United Airlines
Deal found 1/27$335
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/241:40 pm
JAX
-
DSM
2 stops8h 30m
Southwest
Tue 3/36:10 am
DSM
-
JAX
2 stops11h 00m
Southwest
Deal found 1/27$345
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:27 pm
JAX
-
DSM
1 stop6h 16m
United Airlines
Sat 4/258:20 am
DSM
-
JAX
1 stop7h 00m
United Airlines
Deal found 1/26$359
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:15 am
JAX
-
DSM
1 stop9h 00m
United Airlines
Sun 5/1011:40 am
DSM
-
JAX
1 stop7h 04m
United Airlines
Deal found 1/27$371
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:50 pm
JAX
-
DSM
2 stops8h 25m
Southwest
Sun 5/105:20 am
DSM
-
JAX
2 stops9h 15m
Southwest
Deal found 1/27$381
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:30 am
JAX
-
DSM
1 stop5h 18m
Delta
Mon 3/305:20 pm
DSM
-
JAX
1 stop4h 41m
Delta
Deal found 1/27$383
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:37 am
JAX
-
DSM
2 stops8h 47m
United Airlines
Sun 3/82:04 pm
DSM
-
JAX
1 stop6h 31m
United Airlines
Deal found 1/28$388
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:50 am
JAX
-
DSM
2 stops7h 20m
Southwest
Sun 3/85:25 am
DSM
-
JAX
2 stops7h 30m
Southwest
Deal found 1/28$393
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:40 am
JAX
-
DSM
1 stop5h 05m
Southwest
Sun 4/264:20 pm
DSM
-
JAX
1 stop4h 45m
Southwest
Deal found 1/28$407

Find flight deals from Jacksonville to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$335
(United Airlines)

One-way from

$141
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$286

Good one-way deal

$124 or less
Provider with most accurate pricing for Jacksonville-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jacksonville-Des Moines flights.
Search Deals
From Jacksonville to Des Moines
Search Deals
One-way flight from Jacksonville to Des Moines
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($122 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 11% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a one-way flight from Jacksonville to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Jacksonville to Des Moines that are best for you.

Fly from

Jacksonville

Fly to

Des Moines

Route

Depart

Return

Price

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Tue 2/24

4:55 pm-9:41 pm

1 stop5h 46m

Des Moines

Tue 3/3

8:00 am-3:26 pm

1 stop6h 26m

$335

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Wed 2/25

7:45 am-2:27 pm

1 stop7h 42m

Des Moines

Wed 3/4

2:59 pm-9:32 pm

1 stop5h 33m

$335

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Wed 2/25

11:50 am-9:10 pm

2 stops10h 20m

Des Moines

Wed 3/4

8:35 am-7:55 pm

2 stops10h 20m

$345

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Thu 4/23

5:27 pm-10:43 pm

1 stop6h 16m

Des Moines

Sat 4/25

8:20 am-4:20 pm

1 stop7h 00m

$359

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Fri 3/27

6:30 am-10:48 am

1 stop5h 18m

Des Moines

Mon 3/30

5:20 pm-11:01 pm

1 stop4h 41m

$383

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Fri 3/27

2:30 pm-9:51 pm

1 stop8h 21m

Des Moines

Mon 3/30

1:52 pm-7:17 pm

1 stop4h 25m

$383

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Fri 4/24

8:00 am-12:29 pm

1 stop5h 29m

Des Moines

Mon 4/27

8:04 am-2:13 pm

1 stop5h 09m

$383

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Thu 3/5

6:00 am-10:30 am

1 stop5h 30m

Des Moines

Sun 3/8

2:04 pm-9:35 pm

1 stop6h 31m

$383

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Fri 2/27

3:55 pm-10:20 pm

2 stops7h 25m

Des Moines

Mon 3/2

7:00 am-12:53 pm

1 stop4h 53m

$388

JacksonvilleDes Moines

JAX - DSM

JAXDSM

Jacksonville

Wed 2/25

7:56 pm-6:42 pm

3 stops23h 46m

$141

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 19 results
1
2

Compare providers for flights from Jacksonville to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to Des Moines in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
Kiwi.comPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Jacksonville-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Jacksonville-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Jacksonville-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Jacksonville-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Jacksonville to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Des Moines

What is the cheapest month to book a flight from Jacksonville to Des Moines?

Currently, July is the cheapest month in which you can book a flight from Jacksonville to Des Moines (average of $49). Flying from Jacksonville to Des Moines in February is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated January 29, 2026.
Read through reviews of airlines operating flights from Jacksonville to Des Moines, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,127 reviews
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,215 reviews
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,206 reviews
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Allegiant Air
7.2
Good
706 reviews
Southwest
8.0
Very good
4,267 reviews

Crew

8.6

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Jacksonville to Des Moines flight route?

    The Jacksonville to Des Moines flight path was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Jacksonville to Des Moines?

    Departing from Jacksonville to Des Moines will take you 5h 46m. The distance from Jacksonville to Des Moines is about 1012 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Jacksonville to Des Moines round-trip?

    Cheapflights users have booked flights from Jacksonville to Des Moines round-trip from $81. Other airlines that can offer you cheap pricing are Delta, from $130, and United Airlines, from $232. These flights start at 74% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Jacksonville to Des Moines one-way?

    $40 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $150 and $182, respectively.

  • What are the cheapest flights from Jacksonville to Des Moines?

    On average you can expect to pay $131 for a flight from Jacksonville to Des Moines. The cheapest flight overall is $123 while the most popular route, (Jacksonville - Des Moines) is currently priced at $335.

  • Can I find deals for flights from Jacksonville to Des Moines that include hotel bookings?

    Yes. In addition to deals on Jacksonville to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Des Moines.

  • Can I find deals for business class flights from Jacksonville to Des Moines?

    Yes. Cheapflights offers flight deals from Jacksonville to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to Des Moines?

    Currently, July is the cheapest month in which you can book a flight from Jacksonville to Des Moines (average of $49). Flying from Jacksonville to Des Moines in February is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Alternative routes for Jacksonville to Des Moines

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Top 5 airlines flying from Jacksonville to Des Moines

Discover the top 5 airlines that operate flights from Jacksonville to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$81Average$94FlexibilityNo cancel feeOn-time88%
DeltaCheapest$130Average$369FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$232Average$375FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$280Average$347FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$286Average$341FlexibilityNo cancel feeOn-time71%

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