$70+ Cheap flights from Jacksonville to Des Moines (JAX - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/25. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — DSM
may. 30 — jun. 61
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Jacksonville to Des MoinesExplore the most affordable flight options available from Jacksonville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 30, 2026.
Explore the most affordable flight options available from Jacksonville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/259:21 pm
JAX
- DSM
Nonstop2h 37m
Allegiant Air
dom. 6/284:01 pm
DSM
- JAX
Nonstop2h 29m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/259:21 pm
JAX
- DSM
Nonstop2h 37m
Multiple Airlines
lun. 6/295:45 pm
DSM
- JAX
2 stops22h 48m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/26:30 pm
JAX
- DSM
2 stops20h 01m
Multiple Airlines
dom. 6/74:01 pm
DSM
- JAX
Nonstop2h 29m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/253:59 pm
JAX
- DSM
1 stop6h 48m
Multiple Airlines
dom. 6/284:01 pm
DSM
- JAX
Nonstop2h 29m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/259:21 pm
JAX
- DSM
Nonstop2h 37m
Allegiant Air
sáb. 6/275:06 pm
DSM
- JAX
2 stops24h 29m
Allegiant Air
Deal found 4/27![Allegiant Air logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/197:22 pm
JAX
- DSM
2 stops19h 08m
Allegiant Air
dom. 6/214:01 pm
DSM
- JAX
Nonstop2h 29m
Allegiant Air
Deal found 4/27![Allegiant Air logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/259:21 pm
JAX
- DSM
Nonstop2h 37m
Multiple Airlines
sáb. 6/275:06 pm
DSM
- JAX
3 stops23h 27m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/267:59 pm
JAX
- DSM
1 stop5h 18m
American Airlines
mar. 6/24:48 pm
DSM
- JAX
1 stop5h 54m
American Airlines
Deal found 4/26![American Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/26:20 am
JAX
- DSM
2 stops8h 01m
American Airlines
mié. 6/36:55 am
DSM
- JAX
1 stop4h 59m
American Airlines
Deal found 4/29![American Airlines logo]()
$356
Best flights from Jacksonville to Des MoinesDiscover carefully curated flight deals from Jacksonville to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated abril 30, 2026.
Discover carefully curated flight deals from Jacksonville to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated abril 30, 2026.
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/15:30 am
JAX
- DSM
1 stop6h 15m
Delta
sáb. 7/44:47 pm
DSM
- JAX
1 stop6h 12m
Delta
Deal found 4/26![Delta logo]()
$389
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/296:20 am
JAX
- DSM
2 stops7h 58m
American Airlines
lun. 6/14:48 pm
DSM
- JAX
1 stop5h 54m
American Airlines
Deal found 4/25![American Airlines logo]()
$421
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/31:15 pm
JAX
- DSM
2 stops9h 55m
Southwest
sáb. 6/65:10 am
DSM
- JAX
1 stop5h 05m
Southwest
Deal found 4/29![Southwest logo]()
$424
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/187:30 am
JAX
- DSM
1 stop5h 49m
United Airlines
mié. 8/1911:23 am
DSM
- JAX
1 stop5h 15m
United Airlines
Deal found 4/27![United Airlines logo]()
$441
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/297:04 pm
JAX
- DSM
1 stop4h 28m
Delta
lun. 6/16:41 pm
DSM
- JAX
1 stop4h 42m
Delta
Deal found 4/27![Delta logo]()
$416
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/114:30 pm
JAX
- DSM
1 stop6h 25m
Southwest
lun. 7/134:40 pm
DSM
- JAX
1 stop4h 55m
Southwest
Deal found 4/26![Southwest logo]()
$427
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/122:27 pm
JAX
- DSM
1 stop8h 26m
American Airlines
mar. 5/196:00 am
DSM
- JAX
2 stops9h 10m
American Airlines
Deal found 4/28![American Airlines logo]()
$434
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/216:30 am
JAX
- DSM
1 stop4h 44m
Delta
lun. 8/245:45 am
DSM
- JAX
1 stop5h 40m
Delta
Deal found 4/26![Delta logo]()
$427
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/115:40 pm
JAX
- DSM
1 stop5h 49m
Delta
lun. 7/135:41 am
DSM
- JAX
1 stop7h 04m
Delta
Deal found 4/29![Delta logo]()
$427
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/1212:50 pm
JAX
- DSM
1 stop6h 03m
Delta
mar. 5/196:41 pm
DSM
- JAX
1 stop4h 41m
Delta
Deal found 4/26![Delta logo]()
$429
Last-minute flights from Jacksonville to Des MoinesDiscover last-minute flight deals from Jacksonville to Des Moines. Data last updated abril 30, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to Des Moines. Data last updated abril 30, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/104:30 pm
JAX
- DSM
1 stop6h 50m
Southwest
jue. 5/144:20 pm
DSM
- JAX
1 stop4h 45m
Southwest
Deal found 4/25![Southwest logo]()
$507
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/127:04 pm
JAX
- DSM
1 stop4h 28m
Delta
mar. 5/196:41 pm
DSM
- JAX
1 stop4h 41m
Delta
Deal found 4/27![Delta logo]()
$429
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/126:00 am
JAX
- DSM
2 stops8h 48m
American Airlines
mar. 5/196:00 am
DSM
- JAX
1 stop6h 47m
American Airlines
Deal found 4/28![American Airlines logo]()
$434
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/186:00 am
JAX
- DSM
2 stops8h 48m
American Airlines
jue. 5/211:40 pm
DSM
- JAX
1 stop6h 12m
American Airlines
Deal found 4/28![American Airlines logo]()
$513
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/267:59 pm
JAX
- DSM
1 stop5h 18m
American Airlines
mar. 6/24:48 pm
DSM
- JAX
1 stop5h 54m
American Airlines
Deal found 4/26![American Airlines logo]()
$351
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/266:30 am
JAX
- DSM
2 stops8h 35m
Southwest
mar. 6/25:30 am
DSM
- JAX
2 stops10h 50m
Southwest
Deal found 4/26![Southwest logo]()
$466
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/297:05 am
JAX
- DSM
1 stop5h 03m
Delta
lun. 6/16:41 pm
DSM
- JAX
1 stop4h 42m
Delta
Deal found 4/28![Delta logo]()
$416
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/296:20 am
JAX
- DSM
2 stops7h 58m
American Airlines
lun. 6/14:48 pm
DSM
- JAX
1 stop5h 54m
American Airlines
Deal found 4/29![American Airlines logo]()
$421
One-way flights from Jacksonville to Des MoinesSearch for one-way flight options from Jacksonville to Des Moines. Find affordable one-way fares based on user searches. Data last updated abril 30, 2026.
Search for one-way flight options from Jacksonville to Des Moines. Find affordable one-way fares based on user searches. Data last updated abril 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/103:07 pm
JAX
- DSM
2 stops32h 50m
Allegiant Air
Deal found 4/28![Allegiant Air logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/129:03 pm
JAX
- DSM
2 stops41h 43m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/79:37 am
JAX
- DSM
3 stops38h 20m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/71:59 pm
JAX
- DSM
3 stops33h 58m
Allegiant Air
Deal found 4/28![Allegiant Air logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/89:45 pm
JAX
- DSM
3 stops41h 01m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/109:37 am
JAX
- DSM
3 stops38h 20m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/911:28 am
JAX
- DSM
2 stops28h 47m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$321
Find flight deals from Jacksonville to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated abril 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $70 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $416 |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 30, 2026.
Use the filters below to find and compare flights from Jacksonville to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
mié. 7/1
5:30 am-10:45 am
1 stop6h 15m
Des Moines
sáb. 7/4
4:47 pm-11:59 pm
1 stop6h 12m
$389
Quickest round-trip
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
vie. 5/29
7:04 pm-10:32 pm
1 stop4h 28m
Des Moines
lun. 6/1
6:41 pm-12:23 am
1 stop4h 42m
$416
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
vie. 5/29
6:20 am-1:18 pm
2 stops7h 58m
Des Moines
lun. 6/1
4:48 pm-11:42 pm
1 stop5h 54m
$421
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
mié. 6/3
1:15 pm-10:10 pm
2 stops9h 55m
Des Moines
sáb. 6/6
5:10 am-11:15 am
1 stop5h 05m
$424
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
sáb. 7/11
4:30 pm-9:55 pm
1 stop6h 25m
Des Moines
lun. 7/13
4:40 pm-10:35 pm
1 stop4h 55m
$427
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
vie. 8/21
6:30 am-10:14 am
1 stop4h 44m
Des Moines
lun. 8/24
5:45 am-12:25 pm
1 stop5h 40m
$427
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
sáb. 7/11
5:40 pm-10:29 pm
1 stop5h 49m
Des Moines
lun. 7/13
5:41 am-1:45 pm
1 stop7h 04m
$427
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
mar. 5/12
12:50 pm-5:53 pm
1 stop6h 03m
Des Moines
mar. 5/19
6:41 pm-12:22 am
1 stop4h 41m
$429
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
mar. 5/12
2:27 pm-9:53 pm
1 stop8h 26m
Des Moines
mar. 5/19
6:00 am-4:10 pm
2 stops9h 10m
$434
JacksonvilleDes Moines
JAX - DSM
JAXDSM
Jacksonville
mar. 8/18
7:30 am-12:19 pm
1 stop5h 49m
Des Moines
mié. 8/19
11:23 am-5:38 pm
1 stop5h 15m
$441
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Jacksonville to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to Des Moines in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Jacksonville-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Jacksonville-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Jacksonville-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Jacksonville-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Jacksonville to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Jacksonville with our price prediction graph.
JAX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to Des Moines
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated abril 30, 2026.
Read through reviews of airlines operating flights from Jacksonville to Des Moines, such as Delta,United Airlines, andAllegiant Air. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Comfort
7.9
Boarding
8.1
Overall
7.9
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Food
7.2
Comfort
7.9
Boarding
8.1
Overall
7.9
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Food
7.2
Comfort
7.9
Boarding
8.1
Overall
7.9
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Food
7.2
Comfort
7.9
Boarding
8.1
Overall
7.9
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Food
7.2
Comfort
7.9
Boarding
8.1
Overall
7.9
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on abril 30, 2026.
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Jacksonville and Des Moines flights
Browse other Jacksonville and Des Moines flight options. Last updated on abril 30, 2026.
Other flights from Jacksonville
Browse through other flights departing from Jacksonville. Flights are based on user searches made on Cheapflights and were last updated on abril 30, 2026.
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Top 4 airlines flying from Jacksonville to Des Moines
Discover the top 4 airlines that operate flights from Jacksonville to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$82 | Average$92 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$130 | Average$464 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$286 | Average$385 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$351 | Average$426 | FlexibilityNo cancel fee | On-time69% |