HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$314+ Cheap flights from Harrisburg to Des Moines (MDT - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — DSM
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Harrisburg to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Harrisburg to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$314
(Delta)

Popular in

February

Cheapest in

April

Average price

$318
Provider with most accurate pricing for Harrisburg-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Des Moines flights.
Search Deals
From Harrisburg to Des Moines
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($66 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Harrisburg to Des Moines

Cheapest flights from Harrisburg to Des Moines
Explore the most affordable flight options available from Harrisburg to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/216:00 amMDT - DSM
1 stop5h 14mDelta
Mon 8/256:20 amDSM - MDT
1 stop4h 32mDelta
Deal found 4/29$314
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/73:59 pmMDT - DSM
1 stop23h 59mAllegiant Air
Fri 5/98:00 amDSM - MDT
1 stop26h 01mAllegiant Air
Deal found 4/29$324
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/216:15 amMDT - DSM
2 stops8h 55mUnited Airlines
Mon 8/253:25 pmDSM - MDT
1 stop4h 50mUnited Airlines
Deal found 4/28$354
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/287:58 pmMDT - DSM
1 stop5h 00mAmerican Airlines
Mon 6/25:32 amDSM - MDT
1 stop4h 49mAmerican Airlines
Deal found 4/29$377
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/166:24 pmMDT - DSM
2 stops29h 34mMultiple Airlines
Sun 5/183:45 pmDSM - MDT
3 stops24h 49mMultiple Airlines
Deal found 4/28$594

Cheapflights Fare Finder

Customize your flight search to find flights from Harrisburg to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Harrisburg to Des Moines that are best for you.

Fly from

Harrisburg

Fly to

Des Moines

Route

Depart

Return

Price

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 8/21

6:00 am-10:14 am

1 stop5h 14m

Des Moines

Mon 8/25

6:20 am-11:52 am

1 stop4h 32m

$314

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Thu 8/21

6:15 am-2:10 pm

2 stops8h 55m

Des Moines

Mon 8/25

3:25 pm-9:15 pm

1 stop4h 50m

$354

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Wed 5/28

7:58 pm-11:58 pm

1 stop5h 00m

Des Moines

Mon 6/2

5:32 am-11:21 am

1 stop4h 49m

$377

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Fri 5/16

8:52 pm-3:34 pm

1 stop19h 42m

Des Moines

Sun 5/18

12:32 pm-8:02 pm

2 stops30h 30m

$396

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Fri 5/16

6:24 pm-10:58 pm

2 stops29h 34m

Des Moines

Sun 5/18

3:45 pm-5:34 pm

3 stops24h 49m

$594

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Tue 5/6

6:00 am-9:37 am

1 stop4h 37m

$345

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Tue 5/6

6:15 am-9:52 pm

3 stops16h 37m

$968

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Compare providers for flights from Harrisburg to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Des Moines in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Des Moines

What is the cheapest month to book a flight from Harrisburg to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Harrisburg to Des Moines (average of $336). Flying from Harrisburg to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to DSM?

Find hourly flight availability from Harrisburg to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

When flying from Harrisburg to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 15% versus a flight in the morning.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 29, 2025.
Read reviews from past customers who have flown Delta, United Airlines and Allegiant Air from Harrisburg to Des Moines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,936 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Harrisburg to Des Moines round-trip?

    Cheapflights users have booked flights from Harrisburg to Des Moines round-trip from $314. Other airlines that can offer you cheap pricing are United Airlines, from $354, and American Airlines, from $377. You may be able to fly from Harrisburg to Des Moines for 27% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Harrisburg to Des Moines one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $345. American Airlines flights start at $450 while deals on United Airlines start at $455 one-way.

  • Can I find deals for flights from Harrisburg to Des Moines that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Des Moines.

  • Can I find deals for business class flights from Harrisburg to Des Moines?

    Yes. Cheapflights offers flight deals from Harrisburg to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Harrisburg to Des Moines (average of $336). Flying from Harrisburg to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Ames
Altoona
Johnston
Boone
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Harrisburg to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Omaha flights
LaGuardia to Omaha flights
John F Kennedy Intl to Omaha flights
Reagan-National to Omaha flights
Dulles Intl to Omaha flights
John F Kennedy Intl to Des Moines flights
LaGuardia to Des Moines flights
Reagan-National to Des Moines flights
Dulles Intl to Des Moines flights
Philadelphia to Omaha flights
LaGuardia to Cedar Rapids flights
Philadelphia to Des Moines flights
Newark to Des Moines flights
John F Kennedy Intl to Cedar Rapids flights
Newark to Cedar Rapids flights
Reagan-National to Cedar Rapids flights
Dulles Intl to Cedar Rapids flights
Dulles Intl to Moline flights
Pittsburgh to Omaha flights
Newark to Moline flights
Reagan-National to Moline flights
Allentown to Cedar Rapids flights
LaGuardia to Moline flights
Pittsburgh to Des Moines flights
John F Kennedy Intl to Moline flights
Philadelphia to Cedar Rapids flights
Allentown to Omaha flights
Scranton to Omaha flights
Pittsburgh to Cedar Rapids flights
Reagan-National to Sioux City flights
Philadelphia to Moline flights
Newark to Sioux City flights
Harrisburg to Omaha flights
LaGuardia to Sioux City flights
Allentown to Des Moines flights
Dulles Intl to Dubuque flights
Harrisburg to Cedar Rapids flights
Allentown to Moline flights
Dulles Intl to La Crosse flights
Dulles Intl to Sioux City flights
LaGuardia to Dubuque flights
Reagan-National to Dubuque flights
Harrisburg to Moline flights
LaGuardia to La Crosse flights
Newark to Dubuque flights
Reagan-National to Waterloo flights
Reagan-National to La Crosse flights
State College to Cedar Rapids flights
Pittsburgh to Moline flights

Top 3 airlines flying from Harrisburg to Des Moines

Discover the top 3 airlines that operate flights from Harrisburg to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$478FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$251Average$383FlexibilityNo cancel feeOn-time71%
DeltaCheapest$259Average$412FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.