How long is the flight from Harrisburg to Des Moines?

Delta and United Airlines can get you from Harrisburg to Des Moines in just under 4h 26m. Your travel time can differ by up to 59m. The distance from Harrisburg to Des Moines is about 886 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Harrisburg to Des Moines round-trip?

Cheapflights users have booked flights from Harrisburg to Des Moines round-trip from $248. Other airlines that can offer you cheap pricing are United Airlines, from $248, and Delta, from $278. You may be able to fly from Harrisburg to Des Moines for 40% less than the average price by searching for these airlines.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What are the most popular airlines that fly from Harrisburg to Des Moines?

United Airlines, American Airlines and Delta are the most popular airlines when flying from Harrisburg to Des Moines.

Most accurate provider : When it comes to deals on Harrisburg-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Harrisburg-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Harrisburg-Des Moines flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Harrisburg-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Harrisburg to Des Moines that include hotel bookings?

Yes. In addition to deals on Harrisburg to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Harrisburg to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Des Moines.

Can I find deals for business class flights from Harrisburg to Des Moines?

Yes. Cheapflights offers flight deals from Harrisburg to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$279+ Flights from Harrisburg to Des Moines

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Cheap flight deals from Harrisburg to Des Moines

Cheapest flights from Harrisburg to Des Moines
Explore the most affordable flight options available from Harrisburg to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Mon 12/296:00 pmMDT - DSM

1 stop6h 46mAmerican Airlines

Sun 1/46:26 pmDSM - MDT

1 stop4h 53mAmerican Airlines

Deal found 12/28

$354

Best flights from Harrisburg to Des Moines
Discover carefully curated flight deals from Harrisburg to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

Sat 1/106:10 amMDT - DSM

1 stop4h 26mDelta

Wed 1/145:16 pmDSM - MDT

1 stop5h 10mDelta

Deal found 12/26

$279

Sun 1/186:30 amMDT - DSM

1 stop5h 25mUnited Airlines

Sun 1/258:00 amDSM - MDT

1 stop5h 15mUnited Airlines

Deal found 12/26

$310

Sun 1/186:30 amMDT - DSM

1 stop5h 25mUnited Airlines

Mon 1/263:35 pmDSM - MDT

1 stop4h 30mUnited Airlines

Deal found 12/26

$310

Wed 1/215:30 pmMDT - DSM

1 stop5h 20mUnited Airlines

Sat 1/247:50 amDSM - MDT

1 stop5h 25mUnited Airlines

Deal found 12/25

$339

Sat 1/103:10 pmMDT - DSM

1 stop7h 40mUnited Airlines

Wed 1/148:00 amDSM - MDT

1 stop5h 15mUnited Airlines

Deal found 12/26

$349

Sun 1/186:30 amMDT - DSM

1 stop5h 25mUnited Airlines

Tue 1/279:03 amDSM - MDT

2 stops11h 02mUnited Airlines

Deal found 12/26

$394

Sat 2/286:29 amMDT - DSM

1 stop5h 24mUnited Airlines

Wed 3/45:30 amDSM - MDT

2 stops10h 14mUnited Airlines

Deal found 12/26

$394

Last-minute flights from Harrisburg to Des Moines
Discover last-minute flight deals from Harrisburg to Des Moines. Data last updated December 28, 2025 and is based on user searches.

Fri 1/25:24 pmMDT - DSM

1 stop5h 16mUnited Airlines

Sun 1/46:46 pmDSM - MDT

1 stop4h 21mUnited Airlines

Deal found 12/27

$354

Sat 1/106:10 amMDT - DSM

1 stop4h 26mDelta

Wed 1/145:16 pmDSM - MDT

1 stop5h 10mDelta

Deal found 12/26

$279

Sat 1/103:10 pmMDT - DSM

1 stop7h 40mUnited Airlines

Wed 1/148:00 amDSM - MDT

1 stop5h 15mUnited Airlines

Deal found 12/26

$349

Sun 1/186:30 amMDT - DSM

1 stop5h 25mUnited Airlines

Mon 1/263:35 pmDSM - MDT

1 stop4h 30mUnited Airlines

Deal found 12/26

$310

Sun 1/186:30 amMDT - DSM

1 stop5h 25mUnited Airlines

Sun 1/255:30 amDSM - MDT

2 stops10h 04mUnited Airlines

Deal found 12/26

$316

Sun 1/186:30 amMDT - DSM

1 stop5h 25mUnited Airlines

Tue 1/278:00 amDSM - MDT

1 stop5h 15mUnited Airlines

Deal found 12/26

$389

Wed 1/215:30 pmMDT - DSM

1 stop5h 20mUnited Airlines

Sat 1/247:50 amDSM - MDT

1 stop5h 25mUnited Airlines

Deal found 12/25

$339

Find flight deals from Harrisburg to Des Moines

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$269 (Delta)
Popular in	February
Cheapest in	April
Average price	$352

Provider with most accurate pricing for Harrisburg-Des Moines flight deals.

Search Deals

Provider most trusted by Cheapflights users for Harrisburg-Des Moines flights.

Search Deals

From Harrisburg to Des Moines

Search Deals

Highest demand for flights based on searches. 16% potential increase in price ($82 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Harrisburg to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sat 1/10

6:10 am-9:36 am

1 stop4h 26m

Des Moines

Wed 1/14

5:16 pm-11:26 pm

1 stop5h 10m

$279

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sun 1/18

6:30 am-10:55 am

1 stop5h 25m

Des Moines

Sun 1/25

8:00 am-2:15 pm

1 stop5h 15m

$310

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sun 1/18

6:30 am-10:55 am

1 stop5h 25m

Des Moines

Mon 1/26

3:35 pm-9:05 pm

1 stop4h 30m

$310

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Wed 1/21

5:30 pm-9:50 pm

1 stop5h 20m

Des Moines

Sat 1/24

7:50 am-2:15 pm

1 stop5h 25m

$339

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sat 1/10

3:10 pm-9:50 pm

1 stop7h 40m

Des Moines

Wed 1/14

8:00 am-2:15 pm

1 stop5h 15m

$349

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sun 1/18

6:30 am-10:55 am

1 stop5h 25m

Des Moines

Tue 1/27

9:03 am-9:05 pm

2 stops11h 02m

$394

HarrisburgDes Moines

MDT - DSM

MDTDSM

Harrisburg

Sat 2/28

6:29 am-10:53 am

1 stop5h 24m

Des Moines

Wed 3/4

5:30 am-4:44 pm

2 stops10h 14m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Compare providers for flights from Harrisburg to Des Moines

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Des Moines in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Harrisburg-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Harrisburg-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Harrisburg-Des Moines flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Harrisburg-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Harrisburg with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Des Moines

What is the cheapest month to book a flight from Harrisburg to Des Moines?

Currently, July is the cheapest month in which you can book a flight from Harrisburg to Des Moines (average of $148). Flying from Harrisburg to Des Moines in February is currently the most expensive (average of $296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to DSM?

When flying from Harrisburg to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 35% versus a flight at noon.

Reviews of airlines servicing Des Moines

Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Harrisburg to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,019 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,019 reviews

Delta

7.9

Good

8,019 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

United Airlines

7.4

Good

9,113 reviews

Delta

7.9

Good

8,019 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,072 reviews

Delta

7.9

Good

8,019 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from Harrisburg to Des Moines?
Delta and United Airlines can get you from Harrisburg to Des Moines in just under 4h 26m. Your travel time can differ by up to 59m. The distance from Harrisburg to Des Moines is about 886 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Harrisburg to Des Moines round-trip?
Cheapflights users have booked flights from Harrisburg to Des Moines round-trip from $248. Other airlines that can offer you cheap pricing are United Airlines, from $248, and Delta, from $278. You may be able to fly from Harrisburg to Des Moines for 40% less than the average price by searching for these airlines.
Can I find deals for flights from Harrisburg to Des Moines that include hotel bookings?
Yes. In addition to deals on Harrisburg to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Harrisburg to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Des Moines.
Can I find deals for business class flights from Harrisburg to Des Moines?
Yes. Cheapflights offers flight deals from Harrisburg to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Harrisburg to Des Moines?
Currently, July is the cheapest month in which you can book a flight from Harrisburg to Des Moines (average of $148). Flying from Harrisburg to Des Moines in February is currently the most expensive (average of $296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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West Des Moines

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Other flights to Des Moines

Top 3 airlines flying from Harrisburg to Des Moines

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$248	Average$408	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$248	Average$353	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$278	Average$383	FlexibilityNo cancel fee	On-timeN/A

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$279+ Cheap flights from Harrisburg to Des Moines (MDT - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Harrisburg to Des Moines with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Harrisburg to Des Moines

Cheapest flights from Harrisburg to Des MoinesExplore the most affordable flight options available from Harrisburg to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Explore the most affordable flight options available from Harrisburg to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

Find flight deals from Harrisburg to Des Moines

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Harrisburg to Des Moines that are best for you.

Compare providers for flights from Harrisburg to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Des Moines in December.

Best time to book a flight from Harrisburg to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Harrisburg with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Des Moines

What is the cheapest month to book a flight from Harrisburg to Des Moines?

What is the cheapest time of day to fly from MDT to DSM?

Reviews of airlines servicing Des Moines

Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Harrisburg to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Harrisburg to Des Moines?

What are the cheapest airlines flying from Harrisburg to Des Moines round-trip?

Can I find deals for flights from Harrisburg to Des Moines that include hotel bookings?

How can I find direct flights from Harrisburg to Des Moines?

Can I find deals for business class flights from Harrisburg to Des Moines?

What is the cheapest month to book a flight from Harrisburg to Des Moines?

Traveling to a place near Des Moines?

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Alternative routes for Harrisburg to Des Moines

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Top 3 airlines flying from Harrisburg to Des Moines

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Cheapest flights from Harrisburg to Des Moines
Explore the most affordable flight options available from Harrisburg to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.