$253+ Cheap flights from Des Moines (DSM) to Central America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJO
Nov 28 — Dec 51
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Central America with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Des Moines to Central AmericaExplore the most affordable flight options available from Des Moines to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2026.
Explore the most affordable flight options available from Des Moines to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:07 am -
1 stop27h 23m
Wed 12/91:30 pm -
1 stop27h 16m
Deal found 10/28![Multiple Airlines logo]()
$527
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:32 pm -
1 stop18h 11m
Sun 12/136:07 am -
1 stop17h 52m
Deal found 10/28![American Airlines logo]()
$587
This Trip.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:20 pm -
2 stops29h 45m
Mon 12/145:40 pm -
2 stops23h 34m
Deal found 10/25![Avianca logo]()
$606
This Avianca deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/811:27 am -
1 stop7h 23m
Tue 12/158:05 am -
1 stop9h 09m
Deal found 10/24![Multiple Airlines logo]()
$632
This FlightHub deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:20 pm -
2 stops43h 30m
Mon 12/145:40 pm -
2 stops23h 34m
Deal found 10/28![Avianca logo]()
$646
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:07 am -
1 stop27h 23m
Wed 12/91:30 pm -
1 stop27h 16m
Deal found 10/28![Multiple Airlines logo]()
$649
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:32 pm -
2 stops19h 06m
Sat 12/122:39 pm -
2 stops18h 13m
Deal found 10/28![American Airlines logo]()
$670
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:05 am -
1 stop7h 38m
Thu 12/172:02 pm -
1 stop10h 31m
Deal found 10/29![American Airlines logo]()
$679
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:01 am -
2 stops25h 38m
Thu 12/102:04 pm -
2 stops20h 17m
Deal found 10/28![Delta logo]()
$698
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:45 pm -
2 stops28h 02m
Wed 12/162:50 pm -
2 stops19h 56m
Deal found 10/25![United Airlines logo]()
$699
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:20 pm -
2 stops20h 54m
Wed 12/161:20 pm -
1 stop9h 01m
Deal found 10/25![United Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:00 am -
1 stop10h 38m
Tue 12/158:55 am -
1 stop14h 26m
Deal found 10/24![United Airlines logo]()
$712
Best flights from Des Moines to Central AmericaDiscover carefully curated flight deals from Des Moines to Central America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 29, 2026.
Discover carefully curated flight deals from Des Moines to Central America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 29, 2026.
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/16:00 am -
2 stops14h 59m
Sat 2/66:30 am -
1 stop8h 18m
Deal found 10/24![American Airlines logo]()
$586
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/18:00 am -
1 stop7h 24m
Thu 3/42:50 pm -
1 stop7h 43m
Deal found 10/27![United Airlines logo]()
$649
This Avianca deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/169:25 am -
2 stops11h 40m
Sun 1/2412:10 pm -
1 stop10h 20m
Deal found 10/24![Multiple Airlines logo]()
$670
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/610:41 am -
2 stops11h 08m
Wed 1/137:00 am -
1 stop9h 38m
Deal found 10/24![Delta logo]()
$683
This KAYAK deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/203:00 pm -
1 stop21h 35m
Thu 2/251:41 pm -
1 stop8h 49m
Deal found 10/24![Azul logo]()
$903
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/308:00 am -
1 stop13h 49m
Thu 4/13:40 pm -
2 stops21h 31m
Deal found 10/24![United Airlines logo]()
$654
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/67:37 pm -
2 stops17h 55m
Sat 2/132:38 pm -
2 stops10h 02m
Deal found 10/24![American Airlines logo]()
$670
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:45 am -
2 stops15h 30m
Thu 12/37:00 am -
2 stops14h 31m
Deal found 10/28![Delta logo]()
$718
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/183:15 pm -
2 stops22h 59m
Wed 4/2110:55 pm -
2 stops22h 22m
Deal found 10/28![United Airlines logo]()
$672
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/204:56 pm -
2 stops18h 45m
Thu 2/2512:51 pm -
2 stops20h 11m
Deal found 10/24![American Airlines logo]()
$673
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:01 am -
2 stops25h 38m
Fri 12/112:04 pm -
2 stops19h 46m
Deal found 10/28![Delta logo]()
$730
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/264:56 pm -
2 stops20h 33m
Tue 2/22:29 pm -
2 stops19h 48m
Deal found 10/25![American Airlines logo]()
$674
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/266:15 am -
2 stops14h 24m
Wed 2/32:25 pm -
1 stop8h 05m
Deal found 10/29![United Airlines logo]()
$679
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:00 am -
1 stop7h 43m
Sun 12/136:07 am -
1 stop17h 52m
Deal found 10/26![American Airlines logo]()
$675
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:20 am -
1 stop7h 19m
Wed 12/92:04 pm -
1 stop8h 34m
Deal found 10/28![Delta logo]()
$766
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/228:00 am -
1 stop10h 38m
Thu 1/2811:35 am -
1 stop11h 55m
Deal found 10/29![United Airlines logo]()
$701
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/134:56 pm -
2 stops18h 45m
Wed 2/104:06 pm -
1 stop7h 53m
Deal found 10/24![American Airlines logo]()
$693
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:20 pm -
2 stops20h 54m
Wed 12/161:20 pm -
2 stops18h 36m
Deal found 10/25![United Airlines logo]()
$711
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/45:30 am -
1 stop7h 15m
Tue 2/92:00 pm -
1 stop8h 38m
Deal found 10/27![Delta logo]()
$796
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/206:00 am -
1 stop8h 55m
Fri 1/292:29 pm -
2 stops27h 00m
Deal found 10/26![American Airlines logo]()
$723
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:00 am -
1 stop24h 51m
Fri 12/254:11 pm -
1 stop29h 01m
Deal found 10/28![Multiple Airlines logo]()
$1,171
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/63:25 pm -
2 stops21h 54m
Sat 3/137:00 am -
1 stop15h 33m
Deal found 10/26![United Airlines logo]()
$738
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/3010:25 am -
1 stop28h 17m
Thu 2/43:16 pm -
1 stop17h 58m
Deal found 10/25![American Airlines logo]()
$734
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/166:30 pm -
2 stops20h 54m
Sun 1/2411:54 pm -
2 stops20h 28m
Deal found 10/24![United Airlines logo]()
$738
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:30 am -
1 stop7h 42m
Fri 11/207:00 am -
1 stop11h 07m
Deal found 10/25![Delta logo]()
$905
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/127:36 pm -
2 stops18h 01m
Sat 2/274:11 pm -
2 stops16h 53m
Deal found 10/25![American Airlines logo]()
$739
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/204:46 pm -
2 stops19h 38m
Fri 1/291:30 pm -
2 stops22h 47m
Deal found 10/26![United Airlines logo]()
$742
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:30 am -
1 stop8h 14m
Sat 12/53:16 pm -
1 stop7h 22m
Deal found 10/27![Delta logo]()
$943
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:18 pm -
2 stops28h 29m
Mon 12/147:00 am -
1 stop7h 15m
Deal found 10/25![United Airlines logo]()
$753
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/35:00 am -
1 stop6h 43m
Sat 1/91:28 pm -
1 stop8h 48m
Deal found 10/27![American Airlines logo]()
$766
Last-minute flights from Des Moines to Central AmericaDiscover last-minute flight deals from Des Moines to Central America. Data last updated October 29, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Central America. Data last updated October 29, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:45 pm -
2 stops26h 34m
Thu 11/264:40 pm -
1 stop21h 40m
Deal found 10/27![United Airlines logo]()
$758
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:45 pm -
2 stops23h 53m
Thu 4/17:55 am -
1 stop14h 35m
Deal found 10/28![United Airlines logo]()
$717
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:00 am -
1 stop8h 13m
Thu 4/13:24 pm -
1 stop9h 35m
Deal found 10/25![American Airlines logo]()
$746
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:37 pm -
1 stop18h 09m
Tue 2/21:31 pm -
1 stop9h 51m
Deal found 10/28![American Airlines logo]()
$747
This Copa Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:00 am -
2 stops28h 40m
Mon 11/91:59 pm -
2 stops27h 29m
Deal found 10/27![Copa Airlines logo]()
$768
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop7h 46m
Thu 11/191:59 pm -
1 stop9h 45m
Deal found 10/25![American Airlines logo]()
$772
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 am -
2 stops15h 05m
Sat 12/58:05 am -
1 stop13h 20m
Deal found 10/28![Multiple Airlines logo]()
$773
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:23 am -
1 stop8h 23m
Thu 12/32:46 pm -
1 stop8h 19m
Deal found 10/28![American Airlines logo]()
$714
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:45 am -
2 stops15h 30m
Thu 12/37:00 am -
2 stops14h 31m
Deal found 10/28![Delta logo]()
$718
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:45 pm -
2 stops28h 02m
Wed 12/162:50 pm -
2 stops19h 56m
Deal found 10/25![United Airlines logo]()
$699
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:01 am -
1 stop9h 04m
Wed 12/161:11 pm -
1 stop9h 48m
Deal found 10/25![American Airlines logo]()
$770
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:45 pm -
2 stops28h 02m
Mon 12/77:00 am -
1 stop15h 21m
Deal found 10/27![United Airlines logo]()
$774
One-way flights from Des Moines to Central AmericaSearch for one-way flight options from Des Moines to Central America. Find affordable one-way fares based on user searches. Data last updated October 29, 2026.
Search for one-way flight options from Des Moines to Central America. Find affordable one-way fares based on user searches. Data last updated October 29, 2026.
This Priceline deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/49:35 am -
1 stop22h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Frontier logo]()
$253
This Avianca deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/169:25 am -
2 stops11h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$265
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/75:50 pm -
2 stops18h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Southwest logo]()
$298
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/106:30 pm -
2 stops24h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![United Airlines logo]()
$306
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/223:05 pm -
2 stops22h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/34:56 pm -
2 stops18h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![American Airlines logo]()
$320
This FlightHub deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:20 pm -
1 stop27h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Avianca logo]()
$330
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/88:00 am -
1 stop10h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![United Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/124:11 pm -
2 stops19h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![American Airlines logo]()
$336
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/78:00 am -
1 stop12h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![United Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:39 pm -
2 stops24h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/163:31 pm -
1 stop22h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![American Airlines logo]()
$359
Find flight deals from Des Moines to Central America
Keep the following information in mind while searching for Des Moines to Central America flight deals. Data was last updated October 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $435 (American Airlines) |
One-way from | $253 (Priceline) |
Popular in | December |
Cheapest in | January |
Average price | $850 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 29, 2026.
Use the filters below to find and compare flights from Des Moines to Central America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan José
DSM Des Moines - SJO San José Juan Santamaria Intl
DSMSJO
Des Moines
Sun 3/7
5:50 pm-12:05 pm
2 stops18h 15m
San José Juan Santamaria Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$298
Des MoinesPanama City
DSM Des Moines - PTY Panama City Tocumen Intl
DSMPTY
Des Moines
Sun 1/10
8:00 am-2:45 pm
2 stops29h 45m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$306
Des MoinesPanama City
DSM Des Moines - PTY Panama City Tocumen Intl
DSMPTY
Des Moines
Fri 1/8
8:00 am-7:38 pm
1 stop10h 38m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$335
Des MoinesSan Pedro Sula
DSM Des Moines - SAP San Pedro Sula Ramon Villeda
DSMSAP
Des Moines
Fri 2/12
4:11 pm-11:50 am
2 stops19h 39m
San Pedro Sula Ramon Villeda
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$336
Des MoinesSan Pedro Sula
DSM Des Moines - SAP San Pedro Sula Ramon Villeda
DSMSAP
Des Moines
Sun 4/4
3:55 pm-2:23 pm
2 stops23h 28m
San Pedro Sula Ramon Villeda
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$336
Des MoinesManagua
DSM Des Moines - MGA Managua Augusto C Sandino
DSMMGA
Des Moines
Mon 2/22
2:57 pm-1:18 pm
1 stop22h 21m
Managua Augusto C Sandino
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$338
Des MoinesSan Salvador
DSM Des Moines - SAL San Salvador El Salvador Intl
DSMSAL
Des Moines
Sat 1/16
3:31 pm-2:07 pm
1 stop22h 36m
San Salvador El Salvador Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$359
Quickest round-trip
Des MoinesSan José
DSM Des Moines - SJO San José Juan Santamaria Intl
DSMSJO
Des Moines
Sat 3/6
3:00 pm-10:32 pm
1 stop7h 32m
San José Juan Santamaria Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$394
Des MoinesSan José
DSM Des Moines - SJO San José Juan Santamaria Intl
DSMSJO
Des Moines
Sat 3/6
4:11 pm-11:14 am
2 stops19h 03m
San José Juan Santamaria Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$396
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Wed 12/16
3:20 pm-9:25 pm
2 stops30h 05m
Guatemala City La Aurora
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$401
Showing 1-10 of 56 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Central America
Have a flexible travel schedule? Discover the best time to fly to Central America from Des Moines with our price prediction graph.
DSM-SAP
DSM-SAL
DSM-SJO
DSM-PTY
DSM-MGA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Central America
DSM-0CA
DSM-SAP
DSM-SAL
DSM-SJO
DSM-PTY
What is the cheapest month to book a flight from Des Moines to Central America?
Currently, February is the cheapest month in which you can book a flight from Des Moines to Central America (average of $544). Flying from Des Moines to Central America in December is currently the most expensive (average of $929). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Des Moines to Central America?
The best time to book flights from Des Moines to Central America is 45 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Central America
Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated October 29, 2026.
Read through reviews of airlines operating flights from Des Moines to Central America, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Boarding
8.1
Food
7.2
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Boarding
8.1
Food
7.2
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Boarding
8.1
Food
7.2
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Central America
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Complete your trip
Complete your trip to Central America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Central America by cabin class
Find flights from Des Moines to Central America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Central America flights
Browse other Des Moines and Central America flight options. Last updated on October 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Central America countries
Consider these flights traveling to countries located in Central America.
Des Moines to Central America flights
Consider these flights traveling from Des Moines to Central America.
Top 3 airlines flying from Des Moines to Central America
Discover the top 3 airlines that operate flights from Des Moines to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$301 | Average$715 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$417 | Average$730 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$461 | Average$756 | FlexibilityNo cancel fee | On-time69% |