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Central America

$124+ Cheap flights from Des Moines (DSM) to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJO
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Des Moines to Central America

Keep the following information in mind while searching for Des Moines to Central America flight deals. Data was last updated July 3, 2025.

Round-trip from

$317
(Mytrip)

One-way from

$124
(Mytrip)

Popular in

December

Cheapest in

September

Average price

$697
From Des Moines to Central America
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One-way flight from Des Moines to Central America
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Highest demand for flights based on searches. 21% potential increase in price ($202 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($62 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Des Moines to Central America

Cheapest flights from Des Moines to Central America
Explore the most affordable flight options available from Des Moines to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Mytrip deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/177:15 pmDSM - GUA
2 stops29h 14mMultiple Airlines
Sun 8/2412:44 pmGUA - DSM
3 stops30h 57mMultiple Airlines
Deal found 7/3$317
This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/3011:00 amDSM - SJO
2 stops24h 29mMultiple Airlines
Wed 8/611:24 amSJO - DSM
2 stops23h 29mMultiple Airlines
Deal found 7/2$369
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/166:02 amDSM - SAL
1 stop10h 58mMultiple Airlines
Sat 8/2312:05 pmSAL - DSM
1 stop9h 23mMultiple Airlines
Deal found 7/2$396
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:15 amDSM - SAL
1 stop9h 08mUnited Airlines
Tue 9/306:00 amSAL - DSM
1 stop15h 28mUnited Airlines
Deal found 7/2$420
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/155:12 amDSM - SAL
1 stop9h 00mAmerican Airlines
Fri 8/222:40 pmSAL - DSM
1 stop17h 18mAmerican Airlines
Deal found 7/1$436
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:44 amDSM - GUA
1 stop6h 46mDelta
Mon 10/61:35 pmGUA - DSM
1 stop7h 48mDelta
Deal found 7/2$460
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/126:15 amDSM - PTY
1 stop12h 22mUnited Airlines
Wed 10/2210:00 amPTY - DSM
1 stop12h 28mUnited Airlines
Deal found 7/3$461
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/177:20 pmDSM - PTY
2 stops19h 10mAmerican Airlines
Sun 8/243:30 pmPTY - DSM
2 stops25h 18mAmerican Airlines
Deal found 7/3$467
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/106:30 pmDSM - PTY
1 stop18h 17mDelta
Wed 10/222:12 pmPTY - DSM
1 stop8h 11mDelta
Deal found 7/3$470
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/27:00 amDSM - GUA
2 stops13h 12mAmerican Airlines
Mon 10/612:37 pmGUA - DSM
2 stops10h 22mAmerican Airlines
Deal found 7/2$481
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/196:10 pmDSM - MGA
2 stops19h 55mAmerican Airlines
Tue 10/282:05 pmMGA - DSM
2 stops24h 19mAmerican Airlines
Deal found 7/3$493
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/206:30 amDSM - SJO
2 stops13h 25mSouthwest
Mon 8/258:50 amSJO - DSM
2 stops13h 00mSouthwest
Deal found 7/1$517

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Des Moines to Central America that are best for you.

Fly from

Des Moines

Fly to

Central America

Route

Depart

Return

Price

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 8/17

7:15 pm-11:29 pm

2 stops29h 14m

Guatemala City La Aurora

Sun 8/24

12:44 pm-8:41 pm

3 stops30h 57m

$317

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Wed 7/30

11:00 am-10:29 am

2 stops24h 29m

San José Juan Santamaria Intl

Wed 8/6

11:24 am-11:53 am

2 stops23h 29m

$369

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Sat 8/16

6:02 am-4:00 pm

1 stop10h 58m

San Salvador El Salvador Intl

Sat 8/23

12:05 pm-10:28 pm

1 stop9h 23m

$396

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Thu 9/11

6:15 am-2:23 pm

1 stop9h 08m

San Salvador El Salvador Intl

Tue 9/30

6:00 am-10:28 pm

1 stop15h 28m

$420

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Fri 8/15

5:12 am-1:12 pm

1 stop9h 00m

San Salvador El Salvador Intl

Fri 8/22

2:40 pm-8:58 am

1 stop17h 18m

$436

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 10/2

5:44 am-11:30 am

1 stop6h 46m

Guatemala City La Aurora

Mon 10/6

1:35 pm-10:23 pm

1 stop7h 48m

$460

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 10/12

6:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Wed 10/22

10:00 am-10:28 pm

1 stop12h 28m

$461

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 8/17

7:20 pm-2:30 pm

2 stops19h 10m

Panama City Tocumen Intl

Sun 8/24

3:30 pm-4:48 pm

2 stops25h 18m

$467

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Fri 10/10

6:30 pm-12:47 pm

1 stop18h 17m

Panama City Tocumen Intl

Fri 10/17

2:12 pm-10:23 pm

1 stop8h 11m

$470

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 10/2

7:00 am-7:12 pm

2 stops13h 12m

Guatemala City La Aurora

Mon 10/6

12:37 pm-11:59 pm

2 stops10h 22m

$481

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 36 results
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Best time to book a flight from Des Moines to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Central America

What is the cheapest month to book a flight from Des Moines to Central America?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Central America (average of $398). Flying from Des Moines to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CA?

Find hourly flight availability from Des Moines to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Central America as you normally would.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated July 3, 2025.
Read through reviews of airlines operating flights from Des Moines to Central America, such as Southwest, Delta, and Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,266 reviews

Entertainment

7.6

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,266 reviews
Southwest
8.0
Very good
4,266 reviews

Entertainment

7.6

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,982 reviews
Southwest
8.0
Very good
4,266 reviews

Entertainment

7.6

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Copa Airlines
7.5
Good
1,467 reviews
Southwest
8.0
Very good
4,266 reviews

Entertainment

7.6

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,861 reviews
Southwest
8.0
Very good
4,266 reviews

Entertainment

7.6

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,266 reviews

Entertainment

7.6

Crew

8.6

Food

7.0

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Central America?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Central America. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to Central America one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $194. United Airlines flights start at $198 while deals on American Airlines start at $262 one-way.

  • What are the most popular routes from Des Moines to Central America?

    The most popular flight routes from Des Moines to Central America are Des Moines - Panama City Tocumen Intl, Des Moines - San José Juan Santamaria Intl and Des Moines - Belize City Philip S.W.Goldson.

  • Can I find deals for flights from Des Moines to Central America that include hotel bookings?

    Yes. In addition to deals on Des Moines to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Central America.

  • Can I find deals for business class flights from Des Moines to Central America?

    Yes. Cheapflights offers flight deals from Des Moines to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Central America?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to Central America (average of $398). Flying from Des Moines to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Des Moines to Central America

Discover the top 3 airlines that operate flights from Des Moines to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$289Average$630FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$369Average$676FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$419Average$659FlexibilityNo cancel feeOn-time71%

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