$263+ Cheap flights from Des Moines (DSM) to Guatemala City (GUA)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
Nov 7 — Nov 141
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Guatemala City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Guatemala City
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Best
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One-way
Cheapest flights from Des Moines to Guatemala CityExplore the most affordable flight options available from Des Moines to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
Explore the most affordable flight options available from Des Moines to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:31 pm -
2 stops18h 52m
Tue 11/244:15 pm -
2 stops16h 45m
Deal found 10/3![American Airlines logo]()
$698
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
2 stops14h 25m
Wed 12/25:50 am -
2 stops15h 39m
Deal found 10/5![American Airlines logo]()
$729
This Avianca deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
2 stops10h 25m
Wed 12/28:05 am -
1 stop13h 20m
Deal found 10/6![Multiple Airlines logo]()
$741
This Avianca deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1511:27 am -
1 stop7h 23m
Thu 3/115:25 am -
2 stops17h 05m
Deal found 10/7![Multiple Airlines logo]()
$773
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:16 pm -
1 stop20h 50m
Sat 12/511:25 am -
1 stop12h 34m
Deal found 10/3![American Airlines logo]()
$777
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
1 stop11h 39m
Wed 12/22:48 pm -
1 stop7h 33m
Deal found 10/6![United Airlines logo]()
$781
Best flights from Des Moines to Guatemala CityDiscover carefully curated flight deals from Des Moines to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
Discover carefully curated flight deals from Des Moines to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:00 am -
1 stop27h 23m
Tue 11/244:15 pm -
2 stops16h 45m
Deal found 10/3![American Airlines logo]()
$708
This Avianca deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
2 stops10h 25m
Wed 12/28:05 am -
1 stop13h 20m
Deal found 10/6![Multiple Airlines logo]()
$741
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
1 stop11h 39m
Wed 12/22:48 pm -
1 stop7h 33m
Deal found 10/6![United Airlines logo]()
$781
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:39 am -
1 stop6h 48m
Mon 11/92:11 pm -
2 stops20h 08m
Deal found 10/4![Delta logo]()
$1,003
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:42 am -
2 stops14h 35m
Thu 3/116:14 am -
1 stop18h 21m
Deal found 10/6![American Airlines logo]()
$939
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:00 am -
2 stops11h 39m
Wed 11/112:48 pm -
1 stop7h 42m
Deal found 10/3![United Airlines logo]()
$1,009
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:00 am -
2 stops11h 39m
Sun 11/82:10 am -
2 stops15h 18m
Deal found 10/4![United Airlines logo]()
$1,053
Last-minute flights from Des Moines to Guatemala CityDiscover last-minute flight deals from Des Moines to Guatemala City. Data last updated October 8, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Guatemala City. Data last updated October 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:37 pm -
2 stops19h 35m
Mon 11/236:50 am -
1 stop7h 45m
Deal found 10/5![American Airlines logo]()
$792
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:16 pm -
1 stop20h 50m
Sat 12/511:25 am -
1 stop12h 34m
Deal found 10/3![American Airlines logo]()
$777
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:31 pm -
2 stops18h 52m
Tue 11/244:15 pm -
2 stops16h 45m
Deal found 10/3![American Airlines logo]()
$698
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
2 stops14h 25m
Wed 12/25:50 am -
2 stops15h 39m
Deal found 10/5![American Airlines logo]()
$729
This Avianca deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
2 stops10h 25m
Wed 12/28:05 am -
1 stop13h 20m
Deal found 10/6![Multiple Airlines logo]()
$741
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
1 stop11h 39m
Wed 12/22:48 pm -
1 stop7h 33m
Deal found 10/6![United Airlines logo]()
$781
One-way flights from Des Moines to Guatemala CitySearch for one-way flight options from Des Moines to Guatemala City. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
Search for one-way flight options from Des Moines to Guatemala City. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:00 am -
3 stops54h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![Multiple Airlines logo]()
$263
This eDestinos deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:20 am -
3 stops54h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Multiple Airlines logo]()
$370
This Ovago deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:18 pm -
1 stop24h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![Avianca logo]()
$394
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
2 stops14h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![American Airlines logo]()
$403
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
2 stops13h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![United Airlines logo]()
$418
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:35 pm -
2 stops24h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Multiple Airlines logo]()
$436
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:15 pm -
2 stops28h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![United Airlines logo]()
$462
Find flight deals from Des Moines to Guatemala City
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 8, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $698 (American Airlines) |
One-way from | $263 (Kiwi.com) |
Popular in | September |
Cheapest in | February |
Average price | $650 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
Use the filters below to find and compare flights from Des Moines to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Mon 11/9
8:30 pm-8:49 pm
2 stops24h 19m
Guatemala City La Aurora
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$270
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Wed 11/25
7:20 am-1:37 pm
3 stops54h 17m
Guatemala City La Aurora
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$370
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Wed 11/25
3:15 pm-7:39 pm
2 stops28h 24m
Guatemala City La Aurora
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$462
Quickest round-trip
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Wed 12/16
6:00 am-8:27 pm
2 stops14h 27m
Guatemala City La Aurora
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$493
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Tue 11/17
7:00 am-10:23 am
1 stop27h 23m
Guatemala City La Aurora
Tue 11/24
4:15 pm-9:00 am
2 stops16h 45m
$708
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Wed 11/18
8:00 am-6:25 pm
2 stops10h 25m
Guatemala City La Aurora
Wed 12/2
8:05 am-9:25 pm
1 stop13h 20m
$741
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Wed 11/18
8:00 am-7:39 pm
1 stop11h 39m
Guatemala City La Aurora
Wed 12/2
2:48 pm-10:21 pm
1 stop7h 33m
$781
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Thu 12/17
6:42 am-9:17 pm
2 stops14h 35m
Guatemala City La Aurora
Thu 3/11
6:14 am-12:35 am
1 stop18h 21m
$939
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Tue 11/3
5:39 am-12:27 pm
1 stop6h 48m
Guatemala City La Aurora
Mon 11/9
2:11 pm-10:19 am
2 stops20h 08m
$1,003
Des MoinesGuatemala City
DSM Des Moines - GUA Guatemala City La Aurora
DSMGUA
Des Moines
Tue 11/3
8:00 am-7:39 pm
2 stops11h 39m
Guatemala City La Aurora
Wed 11/11
2:48 pm-10:30 pm
1 stop7h 42m
$1,009
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Guatemala City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Guatemala City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Guatemala City flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Des Moines-Guatemala City flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Des Moines-Guatemala City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Guatemala City flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Des Moines with our price prediction graph.
DSM-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Guatemala City
Reviews of airlines servicing Guatemala City
Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated October 8, 2026.
Read through reviews of airlines operating flights from Des Moines to Guatemala City, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
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Complete your trip
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Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 8, 2026.
Des Moines and Guatemala City flights
Browse other Des Moines and Guatemala City flight options. Last updated on October 8, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on October 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Des Moines to Guatemala City
Discover the top 3 airlines that operate flights from Des Moines to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$322 | Average$712 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$468 | Average$737 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$521 | Average$734 | FlexibilityNo cancel fee | On-time69% |