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$124+ Cheap flights from Des Moines (DSM) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
jul. 8 — jul. 151
mar. 7/8
mar. 7/15
1 adult, Economy
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Cheap flight deals from Des Moines to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated julio 3, 2025.

Round-trip from

$317
(Mytrip)

One-way from

$124
(Mytrip)

Popular in

March

Cheapest in

August

Average price

$705
From Des Moines to Guatemala City La Aurora
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One-way flight from Des Moines to Guatemala City La Aurora
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Highest demand for flights based on searches. 18% potential increase in price ($173 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($59 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Des Moines to Guatemala City

Cheapest flights from Des Moines to Guatemala City
Explore the most affordable flight options available from Des Moines to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 3, 2025.

This Mytrip deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/177:15 pmDSM - GUA
2 stops29h 14mMultiple Airlines
dom. 8/2412:44 pmGUA - DSM
3 stops30h 57mMultiple Airlines
Deal found 7/3$317
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/25:44 amDSM - GUA
1 stop6h 46mDelta
lun. 10/61:35 pmGUA - DSM
1 stop7h 48mDelta
Deal found 7/2$460
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/27:00 amDSM - GUA
2 stops13h 12mAmerican Airlines
lun. 10/612:37 pmGUA - DSM
2 stops10h 22mAmerican Airlines
Deal found 7/2$481
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/28:15 amDSM - GUA
2 stops11h 34mUnited Airlines
dom. 10/51:30 amGUA - DSM
2 stops11h 53mUnited Airlines
Deal found 7/1$554

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
Use the filters below to find and compare flights from Des Moines to Guatemala City that are best for you.

Fly from

Des Moines

Fly to

Guatemala City

Route

Depart

Return

Price

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

dom. 8/17

7:15 pm-11:29 pm

2 stops29h 14m

Guatemala City La Aurora

dom. 8/24

12:44 pm-8:41 pm

3 stops30h 57m

$317

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

jue. 10/2

5:44 am-11:30 am

1 stop6h 46m

Guatemala City La Aurora

lun. 10/6

1:35 pm-10:23 pm

1 stop7h 48m

$460

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

jue. 10/2

7:00 am-7:12 pm

2 stops13h 12m

Guatemala City La Aurora

lun. 10/6

12:37 pm-11:59 pm

2 stops10h 22m

$481

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

jue. 10/2

8:15 am-6:49 pm

2 stops11h 34m

Guatemala City La Aurora

dom. 10/5

1:30 am-2:23 pm

2 stops11h 53m

$554

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

dom. 8/24

7:15 pm-11:29 pm

2 stops29h 14m

$124

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

sáb. 8/16

5:44 am-11:30 am

1 stop6h 46m

$323

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

sáb. 8/16

6:50 pm-9:37 pm

3 stops27h 47m

$374

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Des Moines to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guatemala City

What is the cheapest month to book a flight from Des Moines to Guatemala City?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $291). Flying from Des Moines to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to GUA?

Find hourly flight availability from Des Moines to Guatemala City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 3, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 8% on flights from Des Moines to Guatemala City by exploring options for tickets in the afternoon.

How much does it cost to fly round-trip from Des Moines to Guatemala City?

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated julio 3, 2025.
Read through reviews of airlines operating flights from Des Moines to Guatemala City, such as Delta, Copa Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,467 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,861 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Guatemala City round-trip?

    Currently priced at $460, Delta will fly you from Des Moines to Guatemala City and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $481 and $554, respectively. Delta is currently priced 41% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guatemala City.

  • Can I find deals for business class flights from Des Moines to Guatemala City?

    Yes. Cheapflights offers flight deals from Des Moines to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guatemala City?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $291). Flying from Des Moines to Guatemala City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Panajachel
Antigua

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Alternative routes for Des Moines to Guatemala City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Des Moines to Guatemala City

Discover the top 2 airlines that operate flights from Des Moines to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$493Average$770FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$493Average$727FlexibilityNo cancel feeOn-time71%

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