HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guatemala City

$454+ Cheap flights from Des Moines (DSM) to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
Jun 16 — Jun 231
Tue 6/16
Tue 6/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Guatemala City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Guatemala City

Cheapest flights from Des Moines to Guatemala City
Explore the most affordable flight options available from Des Moines to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 17, 2026.

This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:30 am
DSM
-
GUA
1 stop7h 54m
American Airlines
Sun 9/2012:04 pm
GUA
-
DSM
1 stop10h 03m
American Airlines
Deal found 5/14$694
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:34 am
DSM
-
GUA
2 stops11h 46m
American Airlines
Sun 10/47:15 am
GUA
-
DSM
2 stops14h 12m
American Airlines
Deal found 5/14$705
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/54:48 pm
DSM
-
GUA
1 stop7h 42m
American Airlines
Wed 7/152:20 pm
GUA
-
DSM
2 stops17h 03m
American Airlines
Deal found 5/13$714
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:00 am
DSM
-
GUA
2 stops14h 22m
American Airlines
Sat 8/156:00 am
GUA
-
DSM
1 stop16h 36m
American Airlines
Deal found 5/14$742
This Avianca deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:20 am
DSM
-
GUA
2 stops17h 50m
Multiple Airlines
Wed 6/35:25 am
GUA
-
DSM
2 stops16h 15m
Multiple Airlines
Deal found 5/15$758
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:00 am
DSM
-
GUA
1 stop7h 45m
United Airlines
Tue 8/181:30 am
GUA
-
DSM
2 stops11h 46m
United Airlines
Deal found 5/13$760
This KAYAK deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:50 pm
DSM
-
GUA
2 stops22h 33m
GOL
Tue 8/42:20 pm
GUA
-
DSM
2 stops21h 04m
GOL
Deal found 5/17$784

Find flight deals from Des Moines to Guatemala City

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 17, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$694
(American Airlines)

One-way from

$454
(American Airlines)

Popular in

May

Cheapest in

February

Average price

$802
Provider with most accurate pricing for Des Moines-Guatemala City La Aurora flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Guatemala City La Aurora flights.
Search Deals
From Des Moines to Guatemala City La Aurora
Search Deals
One-way flight from Des Moines to Guatemala City La Aurora
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($65 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
Use the filters below to find and compare flights from Des Moines to Guatemala City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Fri 9/11

6:00 am-6:20 pm

2 stops13h 20m

Guatemala City La Aurora

Sun 9/20

7:15 am-11:50 pm

2 stops15h 35m

$698

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 7/1

6:00 am-12:45 pm

1 stop7h 45m

Guatemala City La Aurora

Tue 8/18

1:30 am-2:16 pm

2 stops11h 46m

$760
Quickest round-trip

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sat 6/27

5:35 am-11:30 am

1 stop6h 55m

Guatemala City La Aurora

Sat 7/4

1:00 pm-10:31 pm

1 stop8h 31m

$787

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Tue 8/25

8:00 am-6:49 pm

2 stops11h 49m

Guatemala City La Aurora

Wed 8/26

1:30 am-2:16 pm

2 stops11h 46m

$822

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 7/23

4:48 pm-11:32 pm

1 stop7h 44m

Guatemala City La Aurora

Sat 8/1

1:09 pm-8:23 am

1 stop18h 14m

$871

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 7/23

4:48 pm-11:32 pm

1 stop7h 44m

Guatemala City La Aurora

Sat 8/1

12:35 am-11:58 pm

1 stop22h 23m

$876
Cheapest one-way
Quickest one-way

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 6/28

4:48 pm-11:30 pm

1 stop7h 42m

$454

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/14

Sorted by cheapest first

Compare providers for flights from Des Moines to Guatemala City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Guatemala City in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
OvagoPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Guatemala City flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Des Moines-Guatemala City flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Des Moines-Guatemala City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Guatemala City flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guatemala City

What is the cheapest month to book a flight from Des Moines to Guatemala City?

Currently, February is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $468). Flying from Des Moines to Guatemala City in May is currently the most expensive (average of $802). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Guatemala City?

Reviews of airlines servicing Guatemala City

Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated May 17, 2026.
Read through reviews of airlines operating flights from Des Moines to Guatemala City, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,730 reviews

Crew

8.1

Food

6.6

Boarding

7.7

Overall

7.4

Entertainment

7.1

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
United Airlines
7.4
Good
9,730 reviews
United Airlines
7.4
Good
9,730 reviews

Crew

8.1

Food

6.6

Boarding

7.7

Overall

7.4

Entertainment

7.1

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
American Airlines
7.1
Good
11,654 reviews
United Airlines
7.4
Good
9,730 reviews

Crew

8.1

Food

6.6

Boarding

7.7

Overall

7.4

Entertainment

7.1

Comfort

7.3

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Guatemala City?

    Airlines like Delta, GOL, and United Airlines fly from Des Moines to Guatemala City in about 6h 55m. The time it takes to get you to your destination can typically vary by up to 12h 37m. The distance between Des Moines and Guatemala City is about 1871 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Guatemala City round-trip?

    Currently priced at $468, American Airlines will fly you from Des Moines to Guatemala City and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $494. American Airlines is currently priced 33% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Des Moines to Guatemala City one-way?

    One-way options have recently been found by users for as low as $242 on Avianca. Other airlines that offer cheap prices include United Airlines from $353 and American Airlines from $358 one-way.

  • Can I find deals for flights from Des Moines to Guatemala City that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guatemala City.

  • Can I find deals for business class flights from Des Moines to Guatemala City?

    Yes. Cheapflights offers flight deals from Des Moines to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guatemala City?

    Currently, February is the cheapest month in which you can book a flight from Des Moines to Guatemala City (average of $468). Flying from Des Moines to Guatemala City in May is currently the most expensive (average of $802). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Guatemala City

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Guatemala City flights

Top 2 airlines flying from Des Moines to Guatemala City

Discover the top 2 airlines that operate flights from Des Moines to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$468Average$737FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$494Average$716FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.