$302+ Cheap flights from Des Moines (DSM) to Guatemala City (GUA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GUA
Aug 12 — Aug 191
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Guatemala City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Des Moines to Guatemala CityExplore the most affordable flight options available from Des Moines to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
Explore the most affordable flight options available from Des Moines to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
This Avianca deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
DSM
- GUA
1 stop14h 00m
Multiple Airlines
Fri 8/288:20 am
GUA
- DSM
1 stop12h 03m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$598
This Avianca deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:21 pm
DSM
- GUA
2 stops11h 49m
Multiple Airlines
Sat 8/2910:00 am
GUA
- DSM
2 stops11h 30m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$601
This Avianca deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:21 pm
DSM
- GUA
2 stops10h 49m
Multiple Airlines
Tue 9/16:55 am
GUA
- DSM
2 stops14h 35m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$646
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:41 am
DSM
- GUA
1 stop7h 39m
American Airlines
Sat 9/2611:46 am
GUA
- DSM
1 stop10h 27m
American Airlines
Deal found 7/8![American Airlines logo]()
$733
This Avianca deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:00 am
DSM
- GUA
1 stop14h 00m
Multiple Airlines
Mon 8/318:20 am
GUA
- DSM
1 stop8h 08m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$738
Best flights from Des Moines to Guatemala CityDiscover carefully curated flight deals from Des Moines to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
Discover carefully curated flight deals from Des Moines to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
This Avianca deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:21 pm
DSM
- GUA
2 stops10h 49m
Multiple Airlines
Tue 9/16:55 am
GUA
- DSM
2 stops14h 35m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$687
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:40 am
DSM
- GUA
2 stops14h 54m
American Airlines
Fri 8/2812:07 pm
GUA
- DSM
2 stops20h 53m
American Airlines
Deal found 7/8![American Airlines logo]()
$766
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:40 am
DSM
- GUA
1 stop6h 49m
Delta
Tue 9/112:59 pm
GUA
- DSM
1 stop8h 38m
Delta
Deal found 7/10![Delta logo]()
$787
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:00 am
DSM
- GUA
2 stops9h 30m
United Airlines
Mon 8/1011:55 pm
GUA
- DSM
2 stops11h 25m
United Airlines
Deal found 7/10![United Airlines logo]()
$827
This Avianca deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
DSM
- GUA
1 stop14h 00m
Multiple Airlines
Fri 8/285:25 am
GUA
- DSM
2 stops16h 05m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$746
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:34 am
DSM
- GUA
1 stop7h 48m
American Airlines
Sun 8/302:23 pm
GUA
- DSM
2 stops18h 37m
American Airlines
Deal found 7/11![American Airlines logo]()
$804
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am
DSM
- GUA
1 stop6h 24m
United Airlines
Tue 10/612:27 pm
GUA
- DSM
1 stop8h 48m
United Airlines
Deal found 7/12![United Airlines logo]()
$833
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:15 am
DSM
- GUA
2 stops29h 14m
Delta
Fri 8/2812:59 pm
GUA
- DSM
2 stops19h 31m
Delta
Deal found 7/8![Delta logo]()
$841
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:33 am
DSM
- GUA
1 stop7h 49m
American Airlines
Tue 9/12:23 pm
GUA
- DSM
2 stops22h 02m
American Airlines
Deal found 7/10![American Airlines logo]()
$858
Last-minute flights from Des Moines to Guatemala CityDiscover last-minute flight deals from Des Moines to Guatemala City. Data last updated July 13, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Guatemala City. Data last updated July 13, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
DSM
- GUA
1 stop14h 00m
Multiple Airlines
Fri 8/288:20 am
GUA
- DSM
1 stop12h 03m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$598
This Avianca deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
DSM
- GUA
1 stop14h 00m
Multiple Airlines
Sat 8/2910:00 am
GUA
- DSM
2 stops11h 30m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$737
This Avianca deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:21 pm
DSM
- GUA
2 stops11h 49m
Multiple Airlines
Sat 8/2910:00 am
GUA
- DSM
2 stops11h 30m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$601
This Avianca deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:00 am
DSM
- GUA
1 stop14h 00m
Multiple Airlines
Mon 8/318:20 am
GUA
- DSM
1 stop8h 08m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$738
This Avianca deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:21 pm
DSM
- GUA
2 stops10h 49m
Multiple Airlines
Tue 9/16:55 am
GUA
- DSM
2 stops14h 35m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$646
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:33 am
DSM
- GUA
1 stop7h 49m
American Airlines
Tue 9/112:07 pm
GUA
- DSM
1 stop10h 18m
American Airlines
Deal found 7/11![American Airlines logo]()
$742
One-way flights from Des Moines to Guatemala CitySearch for one-way flight options from Des Moines to Guatemala City. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
Search for one-way flight options from Des Moines to Guatemala City. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
This Avianca deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:21 pm
DSM
- GUA
2 stops10h 49m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$302
This Mytrip deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:20 pm
DSM
- GUA
1 stop28h 40m
Avianca
Deal found 7/8![Avianca logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/202:21 pm
DSM
- GUA
3 stops47h 19m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$469
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/208:15 pm
DSM
- GUA
1 stop17h 31m
United Airlines
Deal found 7/11![United Airlines logo]()
$715
Find flight deals from Des Moines to Guatemala City
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 13, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $598 (Avianca) |
One-way from | $302 (Avianca) |
Popular in | March |
Cheapest in | February |
Average price | $793 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
Use the filters below to find and compare flights from Des Moines to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesGuatemala City
DSM - GUA
DSMGUA
Des Moines
Tue 8/25
1:21 pm-11:10 pm
2 stops10h 49m
Guatemala City La Aurora
Tue 9/1
6:55 am-10:30 pm
2 stops14h 35m
$687
Des MoinesGuatemala City
DSM - GUA
DSMGUA
Des Moines
Fri 8/21
6:00 am-7:00 pm
1 stop14h 00m
Guatemala City La Aurora
Fri 8/28
5:25 am-10:30 pm
2 stops16h 05m
$746
Des MoinesGuatemala City
DSM - GUA
DSMGUA
Des Moines
Fri 8/21
5:40 am-7:34 pm
2 stops14h 54m
Guatemala City La Aurora
Fri 8/28
12:07 pm-10:00 am
2 stops20h 53m
$766
Des MoinesGuatemala City
DSM - GUA
DSMGUA
Des Moines
Tue 8/25
5:40 am-11:29 am
1 stop6h 49m
Guatemala City La Aurora
Tue 9/1
12:59 pm-10:37 pm
1 stop8h 38m
$787
Des MoinesGuatemala City
DSM - GUA
DSMGUA
Des Moines
Sun 8/23
6:34 am-1:22 pm
1 stop7h 48m
Guatemala City La Aurora
Sun 8/30
2:23 pm-10:00 am
2 stops18h 37m
$804
Des MoinesGuatemala City
DSM - GUA
DSMGUA
Des Moines
Fri 8/7
6:00 am-2:30 pm
2 stops9h 30m
Guatemala City La Aurora
Mon 8/10
11:55 pm-12:20 pm
2 stops11h 25m
$827
Quickest round-trip
Des MoinesGuatemala City
DSM - GUA
DSMGUA
Des Moines
Mon 10/5
6:00 am-11:24 am
1 stop6h 24m
Guatemala City La Aurora
Tue 10/6
12:27 pm-10:15 pm
1 stop8h 48m
$833
Des MoinesGuatemala City
DSM - GUA
DSMGUA
Des Moines
Fri 8/21
7:15 am-11:29 am
2 stops29h 14m
Guatemala City La Aurora
Fri 8/28
12:59 pm-9:30 am
2 stops19h 31m
$841
Des MoinesGuatemala City
DSM - GUA
DSMGUA
Des Moines
Tue 8/25
6:33 am-1:22 pm
1 stop7h 49m
Guatemala City La Aurora
Tue 9/1
2:23 pm-1:25 pm
2 stops22h 02m
$858
Cheapest one-way
Quickest one-way
Des MoinesGuatemala City
DSM - GUA
DSMGUA
Des Moines
Sat 8/22
1:21 pm-11:10 pm
2 stops10h 49m
$302
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Guatemala City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Guatemala City in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Guatemala City flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Des Moines-Guatemala City flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Des Moines-Guatemala City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Guatemala City flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Des Moines with our price prediction graph.
DSM-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guatemala City
Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated July 13, 2026.
Read through reviews of airlines operating flights from Des Moines to Guatemala City, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
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Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 13, 2026.
Des Moines and Guatemala City flights
Browse other Des Moines and Guatemala City flight options. Last updated on July 13, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on July 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Guatemala City
Discover the top 2 airlines that operate flights from Des Moines to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$468 | Average$728 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$521 | Average$723 | FlexibilityNo cancel fee | On-time69% |