$363+ Cheap flights from Guatemala City (GUA) to Des Moines (DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
GUA — DSM
Nov 23 — Nov 301
Round-trip
1 adult, Economy
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Find cheap flights from Guatemala City to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Guatemala City to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Guatemala City to Des MoinesExplore the most affordable flight options available from Guatemala City to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
Explore the most affordable flight options available from Guatemala City to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/298:05 am -
1 stop13h 18m
Sat 1/308:00 am -
1 stop10h 50m
Deal found 10/20![Multiple Airlines logo]()
$652
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/298:05 am -
1 stop15h 12m
Fri 1/298:00 am -
1 stop10h 50m
Deal found 10/21![Multiple Airlines logo]()
$661
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:00 am -
1 stop7h 13m
Fri 1/298:00 am -
2 stops11h 39m
Deal found 10/21![United Airlines logo]()
$700
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:00 am -
2 stops16h 58m
Fri 1/299:45 am -
2 stops11h 14m
Deal found 10/20![American Airlines logo]()
$753
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/303:01 pm -
1 stop9h 32m
Fri 1/297:36 am -
2 stops13h 23m
Deal found 10/20![American Airlines logo]()
$763
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:00 am -
2 stops15h 59m
Wed 11/256:45 pm -
2 stops24h 54m
Deal found 10/21![United Airlines logo]()
$768
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:50 am -
1 stop7h 49m
Sat 1/27:38 pm -
1 stop18h 23m
Deal found 10/21![American Airlines logo]()
$780
This KAYAK deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/152:10 am -
2 stops10h 29m
Wed 12/306:42 pm -
2 stops24h 57m
Deal found 10/21![Avianca logo]()
$788
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/308:05 am -
1 stop13h 18m
Fri 1/298:00 am -
1 stop10h 50m
Deal found 10/20![Multiple Airlines logo]()
$803
Best flights from Guatemala City to Des MoinesDiscover carefully curated flight deals from Guatemala City to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
Discover carefully curated flight deals from Guatemala City to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:00 am -
1 stop7h 13m
Fri 1/298:00 am -
2 stops11h 39m
Deal found 10/21![United Airlines logo]()
$700
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/73:45 pm -
2 stops17h 35m
Sun 4/116:45 pm -
2 stops20h 45m
Deal found 10/22![United Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/297:00 am -
2 stops16h 17m
Sat 1/309:25 am -
2 stops13h 23m
Deal found 10/21![United Airlines logo]()
$704
Last-minute flights from Guatemala City to Des MoinesDiscover last-minute flight deals from Guatemala City to Des Moines. Data last updated October 24, 2026 and is based on user searches.
Discover last-minute flight deals from Guatemala City to Des Moines. Data last updated October 24, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:10 am -
2 stops15h 18m
Mon 11/236:05 am -
2 stops15h 20m
Deal found 10/21![United Airlines logo]()
$848
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:50 am -
1 stop16h 15m
Tue 11/243:25 pm -
1 stop7h 22m
Deal found 10/21![American Airlines logo]()
$941
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:57 pm -
2 stops14h 29m
Tue 11/246:05 am -
2 stops15h 20m
Deal found 10/20![United Airlines logo]()
$945
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:25 am -
1 stop11h 22m
Mon 11/233:25 pm -
1 stop22h 45m
Deal found 10/21![American Airlines logo]()
$919
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:00 am -
2 stops15h 59m
Wed 11/256:45 pm -
2 stops24h 54m
Deal found 10/21![United Airlines logo]()
$768
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:50 am -
1 stop7h 49m
Sat 1/27:38 pm -
1 stop18h 23m
Deal found 10/21![American Airlines logo]()
$780
One-way flights from Guatemala City to Des MoinesSearch for one-way flight options from Guatemala City to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
Search for one-way flight options from Guatemala City to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:17 pm -
2 stops23h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:52 pm -
3 stops52h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$364
This Mytrip deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:00 pm -
2 stops47h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Avianca logo]()
$511
Find flight deals from Guatemala City to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Guatemala City (GUA) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $652 (Avianca) |
One-way from | $363 (Kiwi.com) |
Popular in | November |
Cheapest in | February |
Average price | $731 |
Cheapflights Fare Finder
Customize your flight search to find flights from Guatemala City to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
Use the filters below to find and compare flights from Guatemala City to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Guatemala CityDes Moines
GUA Guatemala City La Aurora - DSM Des Moines
GUADSM
Guatemala City La Aurora
Thu 12/10
2:17 pm-2:10 pm
2 stops23h 53m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$363
Quickest round-trip
Guatemala CityDes Moines
GUA Guatemala City La Aurora - DSM Des Moines
GUADSM
Guatemala City La Aurora
Fri 12/11
8:05 am-9:25 pm
1 stop13h 20m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$400
Guatemala CityDes Moines
GUA Guatemala City La Aurora - DSM Des Moines
GUADSM
Guatemala City La Aurora
Fri 12/11
8:00 pm-7:19 pm
2 stops47h 19m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$511
Guatemala CityDes Moines
GUA Guatemala City La Aurora - DSM Des Moines
GUADSM
Guatemala City La Aurora
Tue 12/29
7:00 am-2:13 pm
1 stop7h 13m
Des Moines
Fri 1/29
8:00 am-7:39 pm
2 stops11h 39m
$700
Guatemala CityDes Moines
GUA Guatemala City La Aurora - DSM Des Moines
GUADSM
Guatemala City La Aurora
Wed 4/7
3:45 pm-10:20 am
2 stops17h 35m
Des Moines
Sun 4/11
6:45 pm-2:30 pm
2 stops20h 45m
$701
Guatemala CityDes Moines
GUA Guatemala City La Aurora - DSM Des Moines
GUADSM
Guatemala City La Aurora
Tue 12/29
7:00 am-11:17 pm
2 stops16h 17m
Des Moines
Sat 1/30
9:25 am-10:48 pm
2 stops13h 23m
$704
Sorted by cheapest first
Compare providers for flights from Guatemala City to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guatemala City to Des Moines in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Guatemala City-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guatemala City-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guatemala City-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Guatemala City-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guatemala City-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Guatemala City to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Guatemala City with our price prediction graph.
GUA-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Guatemala City to Des Moines
What is the cheapest month to book a flight from Guatemala City to Des Moines?
Currently, February is the cheapest month in which you can book a flight from Guatemala City to Des Moines (average of $618). Flying from Guatemala City to Des Moines in November is currently the most expensive (average of $1,033). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Guatemala City to Des Moines?
Airfare is below average for this route at the moment.
Guatemala City to Des Moines flights typically cost between $727 and $968 in December.The cheapest round-trip price found within the last 5 days was $652 on Multiple Airlines (Dec 29-Jan 30).
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 24, 2026.
See what other customers who have flown with American Airlines from Guatemala City to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.4
Food
6.4
Overall
7.0
Comfort
7.1
Crew
7.9
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreSherif,Aug 2026
YYZ - ORD
Boarding
7.4
Food
6.4
Overall
7.0
Comfort
7.1
Crew
7.9
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreSherif,Aug 2026
YYZ - ORD
Related info for your journey
Find useful and relevant information for your journey from Guatemala City to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 24, 2026.
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Find flights from Guatemala City to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Guatemala City and Des Moines flights
Browse other Guatemala City and Des Moines flight options. Last updated on October 24, 2026.
Other flights from Guatemala City
Browse through other flights departing from Guatemala City. Flights are based on user searches made on Cheapflights and were last updated on October 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Guatemala City to Des Moines
Discover the top airline that operate flights from Guatemala City to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$606 | Average$705 | FlexibilityNo cancel fee | On-time71% |