$116+ Cheap flights from Wyoming to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
JAC — CHS
Oct 20 — Oct 271
Round-trip
1 adult, Economy
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Find cheap flights from Wyoming to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Wyoming to South Carolina
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Cheapest flights from Wyoming to South CarolinaExplore the most affordable flight options available from Wyoming to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
Explore the most affordable flight options available from Wyoming to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:57 pm -
2 stops35h 40m
Tue 10/2712:05 pm -
1 stop11h 37m
Deal found 9/17![Frontier logo]()
$240
This Priceline deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:43 am -
Nonstop3h 13m
Tue 12/16:00 am -
Nonstop3h 56m
Deal found 9/17![Frontier logo]()
$241
This Mytrip deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:43 am -
Nonstop3h 13m
Tue 11/36:05 am -
2 stops17h 27m
Deal found 9/18![Frontier logo]()
$242
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:12 pm -
2 stops14h 25m
Sat 10/316:05 am -
2 stops17h 27m
Deal found 9/17![Frontier logo]()
$244
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:59 pm -
1 stop7h 43m
Sat 10/2410:38 am -
1 stop6h 59m
Deal found 9/16![United Airlines logo]()
$247
This Expedia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:19 pm -
1 stop11h 46m
Tue 10/2712:05 pm -
1 stop11h 37m
Deal found 9/17![Frontier logo]()
$247
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:50 am -
1 stop4h 25m
Tue 11/106:45 pm -
1 stop5h 55m
Deal found 9/16![Southwest logo]()
$248
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:20 am -
1 stop5h 40m
Sat 10/316:35 am -
1 stop8h 25m
Deal found 9/15![Southwest logo]()
$248
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:45 am -
1 stop5h 20m
Sat 10/244:10 pm -
1 stop7h 00m
Deal found 9/16![Southwest logo]()
$248
This CheapOair deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:02 pm -
1 stop11h 35m
Wed 10/2111:56 am -
1 stop14h 22m
Deal found 9/19![Frontier logo]()
$251
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:55 am -
1 stop5h 35m
Wed 10/72:10 pm -
1 stop10h 30m
Deal found 9/16![Southwest logo]()
$252
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:40 am -
Nonstop3h 22m
Mon 10/266:00 am -
1 stop28h 13m
Deal found 9/17![Frontier logo]()
$252
Best flights from Wyoming to South CarolinaDiscover carefully curated flight deals from Wyoming to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
Discover carefully curated flight deals from Wyoming to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:59 pm -
1 stop7h 30m
Tue 10/205:00 pm -
1 stop8h 53m
Deal found 9/15![United Airlines logo]()
$262
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:59 pm -
1 stop7h 58m
Tue 10/206:58 pm -
1 stop5h 34m
Deal found 9/16![Delta logo]()
$262
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:45 am -
2 stops10h 50m
Tue 11/103:10 pm -
1 stop5h 50m
Deal found 9/16![Southwest logo]()
$289
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:59 pm -
1 stop6h 28m
Wed 10/217:26 am -
1 stop6h 45m
Deal found 9/19![American Airlines logo]()
$355
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:58 am -
1 stop7h 09m
Mon 11/166:51 pm -
1 stop6h 24m
Deal found 9/19![Delta logo]()
$277
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:55 pm -
1 stop7h 17m
Wed 10/282:28 pm -
2 stops9h 57m
Deal found 9/16![United Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:30 am -
1 stop7h 55m
Sat 11/217:10 pm -
1 stop6h 15m
Deal found 9/15![Southwest logo]()
$313
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:35 pm -
1 stop8h 32m
Wed 11/116:56 pm -
1 stop7h 00m
Deal found 9/17![Delta logo]()
$305
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:20 am -
2 stops9h 25m
Sat 10/317:45 am -
2 stops8h 10m
Deal found 9/19![Southwest logo]()
$332
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:05 am -
1 stop7h 20m
Sun 12/68:10 am -
2 stops7h 00m
Deal found 9/16![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:25 pm -
1 stop5h 33m
Mon 11/164:29 pm -
Nonstop3h 35m
Deal found 9/18![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:17 pm -
2 stops12h 04m
Sun 11/155:10 am -
1 stop8h 59m
Deal found 9/17![American Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/163:50 pm -
1 stop5h 47m
Fri 1/225:40 am -
1 stop6h 29m
Deal found 9/16![Delta logo]()
$348
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:55 am -
2 stops6h 30m
Thu 11/193:25 pm -
2 stops9h 15m
Deal found 9/15![Southwest logo]()
$338
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:24 am -
2 stops7h 34m
Tue 10/201:52 pm -
1 stop7h 06m
Deal found 9/15![American Airlines logo]()
$427
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop5h 14m
Tue 10/203:53 pm -
1 stop6h 18m
Deal found 9/15![Delta logo]()
$355
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:52 pm -
1 stop7h 52m
Fri 10/95:00 pm -
1 stop8h 54m
Deal found 9/18![United Airlines logo]()
$398
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:00 am -
2 stops8h 00m
Thu 11/57:00 pm -
1 stop6h 55m
Deal found 9/15![Southwest logo]()
$348
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:59 am -
1 stop6h 31m
Fri 10/235:59 pm -
1 stop5h 52m
Deal found 9/16![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:45 am -
1 stop6h 29m
Tue 11/34:29 pm -
1 stop7h 56m
Deal found 9/16![United Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
2 stops10h 20m
Sun 11/225:25 pm -
1 stop7h 50m
Deal found 9/15![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:15 am -
1 stop6h 59m
Mon 12/71:59 pm -
1 stop8h 21m
Deal found 9/19![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:00 am -
Nonstop3h 08m
Wed 10/214:25 pm -
Nonstop3h 31m
Deal found 9/18![United Airlines logo]()
$418
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:05 pm -
2 stops6h 45m
Sat 10/244:10 pm -
1 stop7h 00m
Deal found 9/15![Southwest logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:59 pm -
1 stop6h 28m
Sun 10/255:00 am -
1 stop6h 16m
Deal found 9/15![American Airlines logo]()
$514
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:07 pm -
1 stop4h 44m
Sun 12/66:02 pm -
1 stop6h 10m
Deal found 9/16![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:57 am -
Nonstop3h 13m
Sun 11/14:56 pm -
1 stop8h 35m
Deal found 9/19![United Airlines logo]()
$425
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:35 am -
2 stops6h 40m
Tue 10/205:00 pm -
1 stop7h 30m
Deal found 9/15![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:45 pm -
1 stop6h 02m
Thu 12/1012:18 pm -
1 stop7h 20m
Deal found 9/18![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:30 pm -
1 stop7h 07m
Fri 10/162:11 pm -
1 stop9h 32m
Deal found 9/18![American Airlines logo]()
$547
Last-minute flights from Wyoming to South CarolinaDiscover last-minute flight deals from Wyoming to South Carolina. Data last updated September 20, 2026 and is based on user searches.
Discover last-minute flight deals from Wyoming to South Carolina. Data last updated September 20, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/512:30 am -
1 stop7h 15m
Wed 10/72:10 pm -
2 stops10h 05m
Deal found 9/16![Southwest logo]()
$252
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:55 am -
1 stop4h 45m
Wed 10/217:20 pm -
1 stop5h 10m
Deal found 9/15![Southwest logo]()
$248
This CheapOair deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:02 pm -
1 stop11h 35m
Wed 10/2111:56 am -
1 stop14h 22m
Deal found 9/19![Frontier logo]()
$251
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:59 pm -
1 stop7h 43m
Sat 10/2410:38 am -
1 stop6h 59m
Deal found 9/16![United Airlines logo]()
$247
This Expedia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:19 pm -
1 stop11h 46m
Tue 10/2712:05 pm -
1 stop11h 37m
Deal found 9/17![Frontier logo]()
$247
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:40 am -
Nonstop3h 22m
Mon 10/266:00 am -
1 stop28h 13m
Deal found 9/17![Frontier logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:57 pm -
2 stops35h 40m
Tue 10/2712:05 pm -
1 stop11h 37m
Deal found 9/17![Frontier logo]()
$240
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:12 pm -
2 stops14h 25m
Sat 10/316:05 am -
2 stops17h 27m
Deal found 9/17![Frontier logo]()
$244
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:45 am -
1 stop5h 20m
Sat 10/244:10 pm -
1 stop7h 00m
Deal found 9/16![Southwest logo]()
$248
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:45 am -
1 stop7h 20m
Sat 10/316:35 am -
2 stops10h 45m
Deal found 9/17![Southwest logo]()
$253
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2612:30 am -
1 stop7h 35m
Sat 10/316:40 am -
2 stops10h 40m
Deal found 9/15![Southwest logo]()
$253
This Mytrip deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:43 am -
Nonstop3h 13m
Tue 11/36:05 am -
2 stops17h 27m
Deal found 9/18![Frontier logo]()
$242
One-way flights from Wyoming to South CarolinaSearch for one-way flight options from Wyoming to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
Search for one-way flight options from Wyoming to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
This eDestinos deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:02 pm -
1 stop11h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Frontier logo]()
$116
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:45 am -
Nonstop3h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![United Airlines logo]()
$117
This CheapOair deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:02 pm -
1 stop11h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Frontier logo]()
$117
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:37 pm -
1 stop11h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$120
This Mytrip deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:10 am -
2 stops24h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Frontier logo]()
$120
This Frontier deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:37 pm -
1 stop11h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:19 pm -
1 stop13h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:02 pm -
1 stop11h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Frontier logo]()
$123
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:30 am -
1 stop8h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$124
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:06 pm -
1 stop7h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$124
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:40 am -
1 stop7h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Southwest logo]()
$124
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:45 am -
1 stop5h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$124
Find flight deals from Wyoming to South Carolina
Keep the following information in mind while searching for Wyoming to South Carolina flight deals. Data was last updated September 20, 2026.
Round-trip from | $240 (Kiwi.com) |
|---|---|
One-way from | $116 (eDestinos) |
Cheapflights Fare Finder
Customize your flight search to find flights from Wyoming to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
Use the filters below to find and compare flights from Wyoming to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Sat 10/31
9:45 am-3:08 pm
Nonstop3h 23m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$117
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Mon 12/14
12:57 am-10:07 am
1 stop7h 10m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$124
DenverSavannah
DEN Denver Intl - SAV Savannah/Hilton Head
DENSAV
Denver Intl
Tue 12/15
6:00 am-12:55 pm
1 stop4h 55m
Savannah/Hilton Head
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$124
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Wed 11/18
8:35 am-5:25 pm
1 stop6h 50m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$127
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Sat 11/14
6:35 am-7:35 pm
2 stops11h 00m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$129
DenverCharlotte
DEN Denver Intl - CLT Charlotte Douglas
DENCLT
Denver Intl
Sat 10/24
6:30 am-6:45 pm
2 stops10h 15m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$129
DenverCharlotte
DEN Denver Intl - CLT Charlotte Douglas
DENCLT
Denver Intl
Tue 10/27
8:45 am-6:30 pm
2 stops7h 45m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$129
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Tue 10/13
11:59 pm-9:14 am
1 stop7h 15m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$132
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Wed 12/16
6:30 am-5:25 pm
2 stops8h 55m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$132
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Sun 10/18
12:59 am-10:42 am
1 stop7h 43m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$139
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Wyoming to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Wyoming with our price prediction graph.
DEN-CLT
DEN-MYR
DEN-GSP
DEN-SAV
DEN-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Wyoming to South Carolina
USWY-USSC
DEN-CLT
DEN-MYR
DEN-GSP
DEN-SAV
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 20, 2026.
See what other customers who have flown with American Airlines from Wyoming to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Food
6.4
Boarding
7.4
Crew
7.9
Entertainment
6.8
Overall
7.0
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Comfort
7.2
Food
6.4
Boarding
7.4
Crew
7.9
Entertainment
6.8
Overall
7.0
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Wyoming to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Wyoming to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Wyoming to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Wyoming and South Carolina flights
Browse other Wyoming and South Carolina flight options. Last updated on September 20, 2026.
Popular flight searches
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Find a return flight route from South Carolina
Find the right flight back to Wyoming after your stay in South Carolina
Wyoming to South Carolina flights
Consider these flights traveling from Wyoming to South Carolina.
Top airline flying from Wyoming to South Carolina
Discover the top airline that operate flights from Wyoming to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$448 | Average$599 | FlexibilityNo cancel fee | On-time71% |