$80+ Cheap flights from San Diego (SAN) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — CHS
May 30 — Jun 61
Round-trip
1 adult, Economy
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Cheapest flights from San Diego to South CarolinaExplore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.
Explore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:25 pm
SAN
- CAE
1 stop7h 50m
Delta
Tue 6/235:35 am
CAE
- SAN
1 stop6h 58m
Delta
Deal found 4/25![Delta logo]()
$333
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/69:25 pm
SAN
- CAE
1 stop7h 51m
American Airlines
Sat 6/137:22 pm
CAE
- SAN
1 stop7h 37m
American Airlines
Deal found 4/28![American Airlines logo]()
$334
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:25 am
SAN
- CLT
1 stop8h 30m
Frontier
Mon 6/2910:14 pm
CLT
- SAN
1 stop13h 55m
Frontier
Deal found 4/29![Frontier logo]()
$335
This Priceline deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:25 am
SAN
- CLT
1 stop8h 10m
Frontier
Mon 5/46:18 pm
CLT
- SAN
1 stop8h 41m
Frontier
Deal found 4/27![Frontier logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:24 pm
SAN
- CHS
1 stop7h 23m
Multiple Airlines
Tue 5/196:00 am
CHS
- SAN
2 stops18h 04m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:55 am
SAN
- AGS
1 stop7h 46m
Delta
Sat 8/155:45 am
AGS
- SAN
1 stop6h 58m
Delta
Deal found 4/28![Delta logo]()
$349
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:25 am
SAN
- CLT
1 stop8h 54m
Frontier
Wed 7/810:14 pm
CLT
- SAN
1 stop13h 51m
Frontier
Deal found 4/28![Frontier logo]()
$354
This Frontier deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:25 am
SAN
- CLT
1 stop8h 53m
Frontier
Sat 8/810:14 pm
CLT
- SAN
1 stop13h 51m
Frontier
Deal found 4/26![Frontier logo]()
$355
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:41 pm
SAN
- AGS
1 stop8h 11m
Delta
Sat 6/65:42 am
AGS
- SAN
1 stop7h 01m
Delta
Deal found 4/29![Delta logo]()
$357
This Frontier deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:04 am
SAN
- CLT
1 stop8h 19m
Frontier
Sat 8/112:01 pm
CLT
- SAN
1 stop9h 57m
Frontier
Deal found 4/26![Frontier logo]()
$357
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:15 am
SAN
- CAE
1 stop7h 47m
Delta
Sat 6/65:40 am
CAE
- SAN
1 stop7h 03m
Delta
Deal found 4/29![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:20 am
SAN
- CAE
1 stop8h 37m
Delta
Tue 12/16:50 pm
CAE
- SAN
1 stop7h 13m
Delta
Deal found 4/30![Delta logo]()
$359
Best flights from San Diego to South CarolinaDiscover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 30, 2026.
Discover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 30, 2026.
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:20 am
SAN
- AGS
1 stop7h 41m
Delta
Sat 8/155:45 pm
AGS
- SAN
1 stop7h 59m
Delta
Deal found 4/26![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:36 pm
SAN
- CAE
1 stop8h 23m
American Airlines
Sat 5/307:21 pm
CAE
- SAN
1 stop7h 38m
American Airlines
Deal found 4/26![American Airlines logo]()
$361
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/610:40 pm
SAN
- CLT
1 stop12h 15m
Southwest
Sat 6/136:00 pm
CLT
- SAN
1 stop7h 55m
Southwest
Deal found 4/26![Southwest logo]()
$387
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/258:32 pm
SAN
- CHS
2 stops10h 51m
United Airlines
Fri 5/297:15 am
CHS
- SAN
1 stop6h 36m
United Airlines
Deal found 4/30![United Airlines logo]()
$443
This JetBlue deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:30 pm
SAN
- SAV
1 stop9h 23m
JetBlue
Wed 8/1910:55 am
SAV
- SAN
1 stop11h 05m
JetBlue
Deal found 4/27![JetBlue logo]()
$447
This Alaska Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:00 am
SAN
- GSP
1 stop8h 06m
Alaska Airlines
Wed 9/211:31 am
GSP
- SAN
1 stop8h 24m
Alaska Airlines
Deal found 4/28![Alaska Airlines logo]()
$493
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:41 pm
SAN
- AGS
1 stop8h 11m
Delta
Sat 6/65:42 am
AGS
- SAN
1 stop7h 01m
Delta
Deal found 4/29![Delta logo]()
$357
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:54 pm
SAN
- HHH
1 stop8h 16m
American Airlines
Sat 10/34:03 pm
HHH
- SAN
1 stop6h 57m
American Airlines
Deal found 4/30![American Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/19:40 pm
SAN
- SAV
1 stop10h 15m
Southwest
Wed 6/106:35 pm
SAV
- SAN
1 stop7h 45m
Southwest
Deal found 4/26![Southwest logo]()
$410
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:25 pm
SAN
- CAE
1 stop7h 50m
Delta
Sun 6/75:35 am
CAE
- SAN
1 stop6h 58m
Delta
Deal found 4/29![Delta logo]()
$373
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2510:40 pm
SAN
- SAV
1 stop8h 43m
United Airlines
Tue 6/3011:30 am
SAV
- SAN
1 stop10h 02m
United Airlines
Deal found 4/29![United Airlines logo]()
$443
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:40 am
SAN
- CLT
2 stops8h 45m
Southwest
Wed 6/244:20 pm
CLT
- SAN
2 stops9h 20m
Southwest
Deal found 4/27![Southwest logo]()
$416
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:50 pm
SAN
- GSP
1 stop6h 53m
Delta
Wed 6/35:40 am
GSP
- SAN
1 stop7h 03m
Delta
Deal found 4/29![Delta logo]()
$383
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:10 am
SAN
- AGS
2 stops10h 22m
American Airlines
Sat 8/153:59 pm
AGS
- SAN
1 stop6h 55m
American Airlines
Deal found 4/30![American Airlines logo]()
$427
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/210:40 pm
SAN
- CLT
1 stop9h 15m
Southwest
Wed 8/126:50 am
CLT
- SAN
1 stop6h 20m
Southwest
Deal found 4/26![Southwest logo]()
$418
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:32 pm
SAN
- CAE
2 stops10h 13m
United Airlines
Sun 6/76:25 am
CAE
- SAN
1 stop7h 56m
United Airlines
Deal found 4/26![United Airlines logo]()
$467
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2311:33 am
SAN
- CHS
1 stop7h 29m
Delta
Sat 5/305:20 am
CHS
- SAN
1 stop7h 23m
Delta
Deal found 4/29![Delta logo]()
$391
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/1410:40 pm
SAN
- CLT
1 stop9h 15m
Southwest
Wed 6/2411:50 am
CLT
- SAN
2 stops9h 30m
Southwest
Deal found 4/28![Southwest logo]()
$423
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:55 pm
SAN
- CAE
2 stops12h 01m
United Airlines
Sat 6/62:18 pm
CAE
- SAN
2 stops12h 36m
United Airlines
Deal found 4/29![United Airlines logo]()
$472
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2011:01 am
SAN
- AGS
1 stop8h 55m
American Airlines
Tue 5/266:30 am
AGS
- SAN
1 stop6h 37m
American Airlines
Deal found 4/26![American Airlines logo]()
$496
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:30 am
SAN
- GSP
1 stop8h 50m
Southwest
Tue 9/227:00 am
GSP
- SAN
1 stop6h 10m
Southwest
Deal found 4/28![Southwest logo]()
$425
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/41:50 pm
SAN
- MYR
1 stop7h 08m
Delta
Mon 6/811:30 am
MYR
- SAN
1 stop9h 51m
Delta
Deal found 4/26![Delta logo]()
$432
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:05 pm
SAN
- CAE
1 stop10h 34m
United Airlines
Sat 5/3010:31 am
CAE
- SAN
2 stops11h 01m
United Airlines
Deal found 4/29![United Airlines logo]()
$476
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:20 am
SAN
- CHS
1 stop8h 15m
Southwest
Sat 7/45:30 am
CHS
- SAN
1 stop10h 05m
Southwest
Deal found 4/30![Southwest logo]()
$425
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:20 pm
SAN
- HHH
1 stop9h 49m
American Airlines
Sun 9/62:48 pm
HHH
- SAN
1 stop9h 23m
American Airlines
Deal found 4/27![American Airlines logo]()
$519
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:45 pm
SAN
- CAE
2 stops14h 40m
Delta
Sat 6/135:51 pm
CAE
- SAN
1 stop8h 09m
Delta
Deal found 4/28![Delta logo]()
$434
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/318:32 pm
SAN
- CAE
2 stops10h 13m
United Airlines
Sun 6/76:25 am
CAE
- SAN
1 stop7h 56m
United Airlines
Deal found 4/28![United Airlines logo]()
$496
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:40 pm
SAN
- CHS
1 stop9h 45m
Southwest
Sun 7/55:15 pm
CHS
- SAN
1 stop8h 20m
Southwest
Deal found 4/30![Southwest logo]()
$432
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:50 pm
SAN
- CAE
1 stop6h 57m
Delta
Sun 6/73:54 pm
CAE
- SAN
1 stop6h 48m
Delta
Deal found 4/27![Delta logo]()
$434
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:45 pm
SAN
- HHH
1 stop9h 47m
American Airlines
Sat 5/165:04 pm
HHH
- SAN
2 stops9h 52m
American Airlines
Deal found 4/27![American Airlines logo]()
$528
Last-minute flights from San Diego to South CarolinaDiscover last-minute flight deals from San Diego to South Carolina. Data last updated April 30, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to South Carolina. Data last updated April 30, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:25 am
SAN
- CLT
1 stop8h 10m
Frontier
Mon 5/46:18 pm
CLT
- SAN
1 stop8h 41m
Frontier
Deal found 4/27![Frontier logo]()
$341
This Expedia deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:25 am
SAN
- CLT
1 stop7h 00m
Frontier
Sun 5/105:20 pm
CLT
- SAN
1 stop18h 22m
Frontier
Deal found 4/29![Frontier logo]()
$380
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1112:33 pm
SAN
- CHS
1 stop23h 46m
Multiple Airlines
Tue 5/196:00 am
CHS
- SAN
2 stops18h 04m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:24 pm
SAN
- CHS
1 stop7h 23m
Multiple Airlines
Tue 5/196:00 am
CHS
- SAN
2 stops18h 04m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$344
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:25 am
SAN
- CLT
1 stop6h 51m
Frontier
Sun 5/175:20 pm
CLT
- SAN
1 stop9h 30m
Frontier
Deal found 4/28![Frontier logo]()
$365
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:50 pm
SAN
- GSP
1 stop6h 53m
Delta
Wed 6/35:40 am
GSP
- SAN
1 stop7h 03m
Delta
Deal found 4/29![Delta logo]()
$383
This Priceline deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:25 am
SAN
- CLT
1 stop8h 30m
Frontier
Sun 5/242:10 pm
CLT
- SAN
1 stop10h 02m
Frontier
Deal found 4/28![Frontier logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:25 am
SAN
- CLT
1 stop8h 53m
Frontier
Tue 5/267:58 pm
CLT
- SAN
2 stops28h 14m
Frontier
Deal found 4/27![Frontier logo]()
$382
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:28 pm
SAN
- CAE
1 stop6h 48m
American Airlines
Sat 5/307:21 pm
CAE
- SAN
1 stop7h 38m
American Airlines
Deal found 4/29![American Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:34 am
SAN
- CAE
1 stop7h 42m
United Airlines
Sat 5/3010:31 am
CAE
- SAN
2 stops11h 01m
United Airlines
Deal found 4/25![United Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:07 pm
SAN
- CLT
2 stops41h 11m
Frontier
Sat 5/308:55 am
CLT
- SAN
1 stop15h 17m
Frontier
Deal found 4/29![Frontier logo]()
$368
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:45 am
SAN
- CLT
1 stop8h 55m
Southwest
Wed 6/31:45 pm
CLT
- SAN
1 stop8h 10m
Southwest
Deal found 4/28![Southwest logo]()
$379
One-way flights from San Diego to South CarolinaSearch for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 30, 2026.
Search for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 30, 2026.
This Frontier deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:25 am
SAN
- CLT
1 stop8h 53m
Frontier
Deal found 4/26![Frontier logo]()
$80
This CheapOair deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:07 pm
SAN
- CLT
1 stop29h 52m
Frontier
Deal found 4/26![Frontier logo]()
$86
This Priceline deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:25 am
SAN
- CLT
1 stop6h 51m
Frontier
Deal found 4/29![Frontier logo]()
$100
This Frontier deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:25 am
SAN
- CLT
1 stop8h 53m
Frontier
Deal found 4/30![Frontier logo]()
$105
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:25 am
SAN
- CLT
1 stop8h 30m
Frontier
Deal found 4/29![Frontier logo]()
$110
This Expedia deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:07 pm
SAN
- CLT
1 stop29h 24m
Frontier
Deal found 4/29![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/249:43 am
SAN
- CLT
2 stops23h 54m
Frontier
Deal found 4/30![Frontier logo]()
$113
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:25 am
SAN
- CLT
1 stop8h 53m
Frontier
Deal found 4/29![Frontier logo]()
$125
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:04 am
SAN
- CLT
1 stop8h 19m
Frontier
Deal found 4/29![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:38 pm
SAN
- MYR
3 stops51h 58m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:25 am
SAN
- MYR
3 stops59h 11m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/81:38 pm
SAN
- MYR
3 stops51h 58m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$173
Find flight deals from San Diego to South Carolina
Keep the following information in mind while searching for San Diego to South Carolina flight deals. Data was last updated April 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $333 (Delta) |
One-way from | $80 (Frontier) |
Popular in | April |
Cheapest in | October |
Average price | $586 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoAugusta
SAN - AGS
SANAGS
San Diego
Wed 8/12
6:20 am-5:01 pm
1 stop7h 41m
Augusta Bush Field
Sat 8/15
5:45 pm-10:44 pm
1 stop7h 59m
$349
San DiegoAugusta
SAN - AGS
SANAGS
San Diego
Wed 6/3
12:41 pm-11:52 pm
1 stop8h 11m
Augusta Bush Field
Sat 6/6
5:42 am-9:43 am
1 stop7h 01m
$357
San DiegoColumbia
SAN - CAE
SANCAE
San Diego
Sat 5/23
12:36 pm-11:59 pm
1 stop8h 23m
Columbia Metropolitan
Sat 5/30
7:21 pm-11:59 pm
1 stop7h 38m
$361
San DiegoColumbia
SAN - CAE
SANCAE
San Diego
Tue 6/2
10:25 pm-9:15 am
1 stop7h 50m
Columbia Metropolitan
Sun 6/7
5:35 am-9:33 am
1 stop6h 58m
$373
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Tue 5/19
1:50 pm-11:43 pm
1 stop6h 53m
Greenville
Wed 6/3
5:40 am-9:43 am
1 stop7h 03m
$383
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Sat 6/6
10:40 pm-1:55 pm
1 stop12h 15m
Charlotte Douglas
Sat 6/13
6:00 pm-10:55 pm
1 stop7h 55m
$387
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Sat 5/23
11:33 am-10:02 pm
1 stop7h 29m
Charleston
Sat 5/30
5:20 am-9:43 am
1 stop7h 23m
$391
San DiegoHilton Head Island
SAN - HHH
SANHHH
San Diego
Sat 9/26
10:54 pm-10:10 am
1 stop8h 16m
Hilton Head Island
Sat 10/3
4:03 pm-8:00 pm
1 stop6h 57m
$403
San DiegoSavannah
SAN - SAV
SANSAV
San Diego
Mon 6/1
9:40 pm-10:55 am
1 stop10h 15m
Savannah/Hilton Head
Wed 6/10
6:35 pm-11:20 pm
1 stop7h 45m
$410
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Wed 6/17
6:40 am-6:25 pm
2 stops8h 45m
Charlotte Douglas
Wed 6/24
4:20 pm-10:40 pm
2 stops9h 20m
$416
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Diego to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Diego with our price prediction graph.
SAN-CAE
SAN-CLT
SAN-CHS
SAN-AGS
SAN-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to South Carolina
SAN-USSC
SAN-CAE
SAN-CLT
SAN-CHS
SAN-AGS
How far ahead should I book a flight from San Diego to South Carolina?
The price you pay for your flight from San Diego to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 77 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from San Diego to South Carolina?
Currently, January is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $134). Flying from San Diego to South Carolina in March is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 30, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from San Diego to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Diego to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to South Carolina by cabin class
Find flights from San Diego to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and South Carolina flights
Browse other San Diego and South Carolina flight options. Last updated on April 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to South Carolina flights
Consider these flights traveling from San Diego to South Carolina.
Top 5 airlines flying from San Diego to South Carolina
Discover the top 5 airlines that operate flights from San Diego to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$134 | Average$268 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$233 | Average$509 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$516 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$457 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$363 | Average$521 | FlexibilityNo cancel fee | On-time63% |