$93+ Cheap flights from San Diego (SAN) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/8. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — CHS
Jun 17 — Jun 241
1 adult, Economy
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Find cheap flights from San Diego to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to South Carolina
Keep the following information in mind while searching for San Diego to South Carolina flight deals. Data was last updated June 12, 2025.
Round-trip from | $216 (Booking.com) |
|---|---|
One-way from | $93 (CheapOair) |
Popular in | December |
Cheapest in | July |
Average price | $411 |
Find flight deals from San Diego to South Carolina
Cheapest flights from San Diego to South CarolinaExplore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
Explore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
This FlightHub deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/227:00 pmSAN - CLT
1 stop15h 40mSpirit Airlines
Sun 7/279:28 pmCLT - SAN
1 stop28h 38mSpirit Airlines
Deal found 6/10![Spirit Airlines logo]()
$251
This CheapOair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/243:10 pmSAN - CLT
1 stop11h 44mMultiple Airlines
Sun 8/319:00 amCLT - SAN
1 stop10h 54mMultiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/308:55 pmSAN - CLT
1 stop10h 00mSouthwest
Wed 9/104:10 pmCLT - SAN
1 stop8h 35mSouthwest
Deal found 6/11![Southwest logo]()
$279
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/309:13 pmSAN - GSP
1 stop8h 05mAmerican Airlines
Wed 7/24:11 pmGSP - SAN
1 stop7h 04mAmerican Airlines
Deal found 6/11![American Airlines logo]()
$287
This JetBlue deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/218:40 pmSAN - CHS
1 stop10h 45mJetBlue
Sat 10/2511:10 amCHS - SAN
1 stop11h 20mJetBlue
Deal found 6/10![JetBlue logo]()
$287
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/246:15 amSAN - MYR
2 stops29h 59mMultiple Airlines
Mon 7/288:58 pmMYR - SAN
2 stops23h 57mMultiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$288
This Mytrip deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/276:15 amSAN - CAE
2 stops31h 31mSpirit Airlines
Tue 7/11:18 pmCAE - SAN
2 stops32h 08mSpirit Airlines
Deal found 6/12![Spirit Airlines logo]()
$294
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/115:13 pmSAN - MYR
2 stops18h 08mSpirit Airlines
Mon 7/148:58 pmMYR - SAN
3 stops29h 08mSpirit Airlines
Deal found 6/11![Spirit Airlines logo]()
$295
This Alaska Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/237:50 pmSAN - CHS
1 stop19h 24mAlaska Airlines
Thu 10/306:59 pmCHS - SAN
1 stop18h 11mAlaska Airlines
Deal found 6/11![Alaska Airlines logo]()
$296
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/169:40 pmSAN - MYR
1 stop9h 28mDelta
Tue 9/3010:55 amMYR - SAN
1 stop9h 33mDelta
Deal found 6/9![Delta logo]()
$297
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1610:10 pmSAN - CHS
1 stop9h 47mDelta
Mon 9/225:25 pmCHS - SAN
1 stop9h 16mDelta
Deal found 6/10![Delta logo]()
$297
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1010:30 pmSAN - AGS
1 stop7h 53mDelta
Thu 8/147:23 pmAGS - SAN
1 stop6h 58mDelta
Deal found 6/10![Delta logo]()
$297
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.
Fly from
San Diego
Fly to
South Carolina
Route
Depart
Return
Price
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Thu 7/10
6:15 am-9:53 am
2 stops24h 38m
Charleston
Thu 7/17
2:28 pm-11:06 pm
2 stops11h 38m
$216
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Tue 7/22
7:00 pm-1:40 pm
1 stop15h 40m
Charlotte Douglas
Sun 7/27
9:28 pm-11:06 pm
1 stop28h 38m
$251
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Sun 8/24
3:10 pm-5:54 am
1 stop11h 44m
Charlotte Douglas
Sun 8/31
9:00 am-4:54 pm
1 stop10h 54m
$261
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Wed 7/30
8:55 pm-9:55 am
1 stop10h 00m
Charlotte Douglas
Wed 9/10
4:10 pm-9:45 pm
1 stop8h 35m
$279
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Mon 6/30
9:13 pm-8:18 am
1 stop8h 05m
Greenville
Wed 7/2
4:11 pm-8:15 pm
1 stop7h 04m
$287
San DiegoMyrtle Beach
SAN - MYR
SANMYR
San Diego
Thu 7/24
6:15 am-3:14 pm
2 stops29h 59m
Myrtle Beach Intl
Mon 7/28
8:58 pm-5:55 pm
2 stops23h 57m
$288
San DiegoColumbia
SAN - CAE
SANCAE
San Diego
Fri 6/27
6:15 am-4:46 pm
2 stops31h 31m
Columbia Metropolitan
Tue 7/1
1:18 pm-6:26 pm
2 stops32h 08m
$294
San DiegoMyrtle Beach
SAN - MYR
SANMYR
San Diego
Fri 7/11
5:13 pm-2:21 pm
2 stops18h 08m
Myrtle Beach Intl
Mon 7/14
8:58 pm-11:06 pm
3 stops29h 08m
$295
San DiegoAugusta
SAN - AGS
SANAGS
San Diego
Sun 8/10
10:30 pm-9:23 am
1 stop7h 53m
Augusta Bush Field
Thu 8/14
7:23 pm-11:21 pm
1 stop6h 58m
$297
San DiegoSavannah
SAN - SAV
SANSAV
San Diego
Mon 8/4
10:45 pm-11:36 am
1 stop9h 51m
Savannah/Hilton Head
Wed 8/6
4:23 pm-10:30 pm
1 stop9h 07m
$297
Showing 1-10 of 60 results
Best time to book a flight from San Diego to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to South Carolina
What is the cheapest month to book a flight from San Diego to South Carolina?
Currently, August is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $217). Flying from San Diego to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to SC?
Find hourly flight availability from San Diego to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.
When flying from San Diego to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Rainfall in South Carolina by month
Plan your trip to South Carolina by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.
Temperature in South Carolina by month
Plan your trip to South Carolina by taking into account the average temperature totals by month.
If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 12, 2025.
To help decide which airline to fly from San Diego to South Carolina, see what other customers have to say about Breeze Airways, Alaska Airlines and Southwest. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.3
Food
6.7
Crew
8.8
Comfort
8.2
Overall
8.1
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Food
6.7
Crew
8.8
Comfort
8.2
Overall
8.1
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Food
6.7
Crew
8.8
Comfort
8.2
Overall
8.1
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Food
6.7
Crew
8.8
Comfort
8.2
Overall
8.1
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Food
6.7
Crew
8.8
Comfort
8.2
Overall
8.1
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Boarding
8.3
Food
6.7
Crew
8.8
Comfort
8.2
Overall
8.1
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Related info for your journey
Find useful and relevant information for your journey from San Diego to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for San Diego to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Top 7 airlines flying from San Diego to South Carolina
Discover the top 7 airlines that operate flights from San Diego to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$126 | Average$255 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$153 | Average$283 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$257 | Average$496 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$462 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$296 | Average$442 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$327 | Average$472 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$573 | Average$816 | FlexibilityNo cancel fee | On-time75% |