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South Carolina

$84+ Cheap flights from San Diego (SAN) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — CHS
feb. 25 — mar. 41
mié. 2/25
mié. 3/4
1 adult, Economy
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Cheap flight deals from San Diego to South Carolina

Cheapest flights from San Diego to South Carolina
Explore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 26, 2026.

This Priceline deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/239:50 am
SAN
-
CLT
1 stop9h 07m
Frontier
lun. 3/25:13 pm
CLT
-
SAN
1 stop9h 55m
Frontier
Deal found 1/26$174
This Frontier deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/236:25 am
SAN
-
CLT
1 stop9h 29m
Frontier
lun. 4/277:49 pm
CLT
-
SAN
1 stop7h 12m
Frontier
Deal found 1/26$180
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/511:59 am
SAN
-
CLT
1 stop27h 49m
Frontier
dom. 3/87:43 pm
CLT
-
SAN
1 stop15h 22m
Frontier
Deal found 1/25$183
This WAYA deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/266:25 am
SAN
-
CLT
1 stop6h 53m
Frontier
dom. 3/15:03 pm
CLT
-
SAN
1 stop10h 05m
Frontier
Deal found 1/26$186
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/119:45 am
SAN
-
CLT
1 stop20h 49m
Frontier
dom. 2/155:13 pm
CLT
-
SAN
1 stop9h 55m
Frontier
Deal found 1/25$192
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/266:36 pm
SAN
-
CLT
2 stops44h 12m
Frontier
dom. 3/87:43 pm
CLT
-
SAN
1 stop15h 22m
Frontier
Deal found 1/25$199
This Frontier deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/166:25 am
SAN
-
CLT
1 stop9h 29m
Frontier
lun. 4/274:31 pm
CLT
-
SAN
1 stop10h 40m
Frontier
Deal found 1/25$201
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/278:35 am
SAN
-
CLT
2 stops30h 13m
Frontier
dom. 3/15:03 pm
CLT
-
SAN
1 stop10h 05m
Frontier
Deal found 1/25$204
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/226:25 am
SAN
-
CLT
2 stops36h 32m
Frontier
dom. 3/15:03 pm
CLT
-
SAN
1 stop10h 05m
Frontier
Deal found 1/25$207
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/257:11 am
SAN
-
CLT
1 stop30h 07m
Multiple Airlines
mié. 3/41:24 pm
CLT
-
SAN
2 stops27h 19m
Multiple Airlines
Deal found 1/24$213
This Expedia deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/249:10 pm
SAN
-
CHS
1 stop10h 48m
JetBlue
mar. 3/311:47 am
CHS
-
SAN
1 stop10h 41m
JetBlue
Deal found 1/25$269
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/108:45 am
SAN
-
CHS
1 stop9h 25m
United Airlines
mar. 3/175:06 pm
CHS
-
SAN
1 stop7h 31m
United Airlines
Deal found 1/26$277

Find flight deals from San Diego to South Carolina

Keep the following information in mind while searching for San Diego to South Carolina flight deals. Data was last updated enero 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$174
(Priceline)

One-way from

$84
(Frontier)

Popular in

December

Cheapest in

October

Average price

$377
Provider with most accurate pricing for San Diego-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Diego-Myrtle Beach Intl flights.
Search Deals
From San Diego to South Carolina
Search Deals
One-way flight from San Diego to South Carolina
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 26, 2026.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.

Fly from

San Diego

Fly to

South Carolina

Route

Depart

Return

Price

San DiegoCharlotte

SAN - CLT

SANCLT

San Diego

vie. 2/6

6:30 am-4:18 pm

1 stop6h 48m

Charlotte Douglas

dom. 2/8

5:13 pm-12:08 am

1 stop9h 55m

$270

San DiegoCharlotte

SAN - CLT

SANCLT

San Diego

jue. 3/26

10:02 pm-4:20 pm

2 stops39h 18m

Charlotte Douglas

dom. 4/5

7:49 pm-12:02 am

1 stop31h 13m

$290

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

lun. 2/23

12:16 pm-9:58 pm

1 stop6h 42m

Charleston

lun. 3/2

5:05 pm-10:44 pm

1 stop8h 39m

$323

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

dom. 3/15

9:55 pm-9:44 am

1 stop8h 49m

Charleston

mié. 3/18

5:56 pm-11:09 pm

1 stop8h 13m

$323

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

lun. 3/9

2:09 pm-12:16 am

1 stop7h 07m

Charleston

jue. 3/12

2:26 pm-6:51 pm

1 stop7h 25m

$323

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

jue. 2/19

2:15 pm-11:54 pm

1 stop6h 39m

Charleston

mar. 2/24

11:29 am-6:16 pm

1 stop9h 47m

$323

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

vie. 5/15

10:10 pm-11:46 am

1 stop10h 36m

Charleston

lun. 5/18

5:55 pm-10:58 pm

1 stop8h 03m

$323

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

jue. 5/7

9:40 pm-9:42 am

1 stop9h 02m

Charleston

lun. 5/11

5:55 pm-10:58 pm

1 stop8h 03m

$323

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

lun. 2/23

10:00 pm-11:18 am

1 stop10h 18m

Charleston

jue. 2/26

5:00 pm-10:48 pm

1 stop8h 48m

$323

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

mar. 3/31

9:55 pm-9:16 am

1 stop8h 21m

Savannah/Hilton Head

mar. 4/7

6:26 pm-11:09 pm

1 stop7h 43m

$323

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/24

Showing 1-10 of 60 results
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Best time to book a flight from San Diego to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to South Carolina

What is the cheapest month to book a flight from San Diego to South Carolina?

Currently, January is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $149). Flying from San Diego to South Carolina in December is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SC?

Find hourly flight availability from San Diego to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 26, 2026.

It’s optimal to fly from San Diego to South Carolina at noon. By choosing this option you can save up to 74% on the cost of your flight, compared to a flight in the evening.

What is the cheapest day to fly from San Diego to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from San Diego to South Carolina. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their San Diego to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated enero 26, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from San Diego to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,268 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Southwest
8.0
Very good
4,268 reviews
Southwest
8.0
Very good
4,268 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Delta
7.9
Good
8,111 reviews
Southwest
8.0
Very good
4,268 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
United Airlines
7.4
Good
9,199 reviews
Southwest
8.0
Very good
4,268 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
American Airlines
7.2
Good
11,189 reviews
Southwest
8.0
Very good
4,268 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
JetBlue
7.2
Good
2,892 reviews
Southwest
8.0
Very good
4,268 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from San Diego to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to South Carolina?

    San Diego (SAN), located 2.6 mi from the city center, is the airport you fly out of when you book flights from San Diego to South Carolina.

  • How long is the flight from San Diego to South Carolina?

    Departing from San Diego to South Carolina will take you 6h 42m. There are 2145 mi between San Diego and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from San Diego to South Carolina one-way?

    $107 is the cheapest one-way deal found within the past few days, from Southwest. You may also be able to find cheap deals on American Airlines and JetBlue, with prices starting from $108 and $126, respectively.

  • What are the most popular routes from San Diego to South Carolina?

    When deciding which route to take from San Diego to South Carolina consider San Diego - Charlotte Douglas, San Diego - Charleston or San Diego - Myrtle Beach Intl as they are the most popular.

  • Can I find deals for flights from San Diego to South Carolina that include hotel bookings?

    Yes. In addition to deals on San Diego to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to South Carolina.

  • Can I find deals for business class flights from San Diego to South Carolina?

    Yes. Cheapflights offers flight deals from San Diego to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to South Carolina?

    Currently, January is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $149). Flying from San Diego to South Carolina in December is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Diego to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from San Diego to South Carolina

Discover the top 5 airlines that operate flights from San Diego to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$126Average$252FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$199Average$499FlexibilityNo cancel feeOn-time69%
DeltaCheapest$213Average$428FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$506FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$344Average$475FlexibilityNo cancel feeOn-time63%

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