$91+ Cheap flights from San Diego (SAN) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — CHS
Apr 16 — Apr 231
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to South Carolina with Cheapflights
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Cheapest flights from San Diego to South CarolinaExplore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.
Explore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.
This flygcity.se deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flygcity.se is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/209:15 pm
SAN
- SAV
1 stop9h 40m
JetBlue
Tue 4/2810:45 am
SAV
- SAN
1 stop12h 20m
JetBlue
Deal found 3/12![JetBlue logo]()
$299
This Cheapflightsfares deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:30 pm
SAN
- CHS
1 stop9h 44m
JetBlue
Fri 5/811:00 am
CHS
- SAN
1 stop12h 04m
JetBlue
Deal found 3/14![JetBlue logo]()
$314
This JetBlue deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/38:30 pm
SAN
- CHS
1 stop9h 44m
JetBlue
Sat 5/911:00 am
CHS
- SAN
1 stop12h 04m
JetBlue
Deal found 3/12![JetBlue logo]()
$319
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:52 am
SAN
- CHS
1 stop7h 33m
United Airlines
Tue 4/215:00 pm
CHS
- SAN
1 stop8h 59m
United Airlines
Deal found 3/12![United Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/810:30 pm
SAN
- MYR
1 stop8h 48m
United Airlines
Wed 4/1511:00 am
MYR
- SAN
1 stop10h 51m
United Airlines
Deal found 3/12![United Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:15 am
SAN
- GSP
1 stop7h 06m
American Airlines
Wed 4/294:28 pm
GSP
- SAN
1 stop7h 22m
American Airlines
Deal found 3/12![American Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:45 am
SAN
- CHS
2 stops10h 15m
Southwest
Tue 4/216:40 am
CHS
- SAN
2 stops9h 15m
Southwest
Deal found 3/12![Southwest logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:53 pm
SAN
- SAV
1 stop8h 06m
American Airlines
Wed 5/137:00 am
SAV
- SAN
1 stop10h 05m
American Airlines
Deal found 3/12![American Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:30 pm
SAN
- HHH
1 stop10h 00m
American Airlines
Sat 9/52:42 pm
HHH
- SAN
1 stop6h 58m
American Airlines
Deal found 3/15![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/189:45 pm
SAN
- CAE
1 stop9h 28m
American Airlines
Tue 4/213:41 pm
CAE
- SAN
1 stop7h 28m
American Airlines
Deal found 3/15![American Airlines logo]()
$369
This JetBlue deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:15 pm
SAN
- SAV
1 stop10h 20m
JetBlue
Tue 5/1211:20 am
SAV
- SAN
1 stop11h 44m
JetBlue
Deal found 3/14![JetBlue logo]()
$370
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:20 am
SAN
- GSP
2 stops8h 20m
Southwest
Tue 5/191:55 pm
GSP
- SAN
1 stop8h 00m
Southwest
Deal found 3/13![Southwest logo]()
$372
Best flights from San Diego to South CarolinaDiscover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 17, 2026.
Discover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 17, 2026.
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:55 pm
SAN
- SAV
1 stop8h 04m
United Airlines
Sat 5/168:08 am
SAV
- SAN
1 stop10h 25m
United Airlines
Deal found 3/12![United Airlines logo]()
$373
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/209:40 pm
SAN
- SAV
1 stop10h 15m
Southwest
Tue 4/282:20 pm
SAV
- SAN
2 stops9h 40m
Southwest
Deal found 3/12![Southwest logo]()
$378
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:17 pm
SAN
- AGS
1 stop7h 39m
American Airlines
Tue 5/125:08 pm
AGS
- SAN
1 stop7h 52m
American Airlines
Deal found 3/13![American Airlines logo]()
$392
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:30 pm
SAN
- HHH
2 stops13h 50m
Delta
Sat 9/512:00 pm
HHH
- SAN
1 stop9h 23m
Delta
Deal found 3/15![Delta logo]()
$394
This Alaska Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:58 am
SAN
- CLT
Nonstop4h 55m
Alaska Airlines
Sat 4/188:56 am
CLT
- SAN
Nonstop5h 13m
Alaska Airlines
Deal found 3/12![Alaska Airlines logo]()
$513
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:25 am
SAN
- SAV
2 stops9h 35m
Southwest
Sat 5/165:20 pm
SAV
- SAN
2 stops9h 05m
Southwest
Deal found 3/12![Southwest logo]()
$383
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/229:45 pm
SAN
- CAE
1 stop9h 29m
United Airlines
Sat 4/2510:50 am
CAE
- SAN
2 stops11h 03m
United Airlines
Deal found 3/13![United Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2310:30 pm
SAN
- GSP
1 stop7h 39m
Delta
Mon 4/276:26 pm
GSP
- SAN
1 stop7h 40m
Delta
Deal found 3/12![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:30 am
SAN
- SAV
1 stop7h 30m
Southwest
Sat 4/256:00 pm
SAV
- SAN
1 stop8h 15m
Southwest
Deal found 3/12![Southwest logo]()
$398
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:37 pm
SAN
- GSP
2 stops10h 09m
United Airlines
Mon 4/275:41 pm
GSP
- SAN
1 stop8h 18m
United Airlines
Deal found 3/12![United Airlines logo]()
$411
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:40 pm
SAN
- AGS
1 stop8h 38m
Delta
Wed 6/37:50 pm
AGS
- SAN
1 stop6h 37m
Delta
Deal found 3/13![Delta logo]()
$412
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:35 am
SAN
- CLT
1 stop9h 35m
Southwest
Mon 6/87:05 pm
CLT
- SAN
1 stop7h 20m
Southwest
Deal found 3/16![Southwest logo]()
$399
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:31 pm
SAN
- AGS
1 stop7h 27m
American Airlines
Tue 5/1210:20 am
AGS
- SAN
2 stops10h 45m
American Airlines
Deal found 3/15![American Airlines logo]()
$495
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:40 pm
SAN
- CHS
1 stop8h 28m
United Airlines
Wed 5/274:16 pm
CHS
- SAN
1 stop9h 09m
United Airlines
Deal found 3/12![United Airlines logo]()
$417
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:40 am
SAN
- CLT
2 stops9h 15m
Southwest
Mon 4/206:15 am
CLT
- SAN
2 stops9h 25m
Southwest
Deal found 3/16![Southwest logo]()
$399
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:55 pm
SAN
- CAE
1 stop8h 23m
Delta
Sun 4/55:34 am
CAE
- SAN
1 stop7h 19m
Delta
Deal found 3/16![Delta logo]()
$449
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:15 am
SAN
- AGS
1 stop9h 22m
American Airlines
Thu 4/163:03 pm
AGS
- SAN
1 stop8h 47m
American Airlines
Deal found 3/16![American Airlines logo]()
$511
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:37 pm
SAN
- MYR
2 stops10h 41m
United Airlines
Sat 5/23:14 pm
MYR
- SAN
2 stops11h 45m
United Airlines
Deal found 3/13![United Airlines logo]()
$442
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/229:15 am
SAN
- GSP
2 stops9h 25m
Southwest
Tue 4/286:45 am
GSP
- SAN
1 stop7h 00m
Southwest
Deal found 3/14![Southwest logo]()
$404
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:30 pm
SAN
- CAE
1 stop7h 45m
Delta
Sun 5/105:38 am
CAE
- SAN
1 stop7h 10m
Delta
Deal found 3/13![Delta logo]()
$457
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2512:45 pm
SAN
- AGS
1 stop6h 34m
American Airlines
Wed 4/14:31 pm
AGS
- SAN
1 stop8h 52m
American Airlines
Deal found 3/15![American Airlines logo]()
$516
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:20 am
SAN
- GSP
2 stops8h 20m
Southwest
Sat 5/95:25 pm
GSP
- SAN
1 stop8h 50m
Southwest
Deal found 3/16![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:32 pm
SAN
- MYR
2 stops10h 27m
United Airlines
Mon 8/3110:28 am
MYR
- SAN
2 stops11h 02m
United Airlines
Deal found 3/12![United Airlines logo]()
$452
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3110:15 pm
SAN
- MYR
1 stop9h 22m
Delta
Fri 6/511:32 am
MYR
- SAN
1 stop9h 29m
Delta
Deal found 3/12![Delta logo]()
$467
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:20 am
SAN
- CLT
2 stops9h 55m
Southwest
Sat 4/257:05 am
CLT
- SAN
1 stop10h 40m
Southwest
Deal found 3/14![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:54 am
SAN
- CHS
1 stop7h 38m
United Airlines
Wed 5/1311:15 am
CHS
- SAN
2 stops11h 49m
United Airlines
Deal found 3/12![United Airlines logo]()
$458
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/510:28 pm
SAN
- HHH
1 stop9h 42m
American Airlines
Sat 7/115:38 pm
HHH
- SAN
1 stop7h 07m
American Airlines
Deal found 3/12![American Airlines logo]()
$587
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:35 am
SAN
- CLT
2 stops9h 05m
Southwest
Tue 4/2111:20 am
CLT
- SAN
2 stops11h 15m
Southwest
Deal found 3/15![Southwest logo]()
$409
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:40 pm
SAN
- HHH
2 stops11h 12m
United Airlines
Mon 7/203:05 pm
HHH
- SAN
2 stops11h 49m
United Airlines
Deal found 3/16![United Airlines logo]()
$459
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:15 pm
SAN
- CLT
1 stop7h 40m
Delta
Fri 6/126:50 pm
CLT
- SAN
1 stop7h 29m
Delta
Deal found 3/15![Delta logo]()
$512
Last-minute flights from San Diego to South CarolinaDiscover last-minute flight deals from San Diego to South Carolina. Data last updated March 17, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to South Carolina. Data last updated March 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/61:01 pm
SAN
- SAV
1 stop7h 58m
American Airlines
Tue 4/144:11 pm
SAV
- SAN
1 stop8h 49m
American Airlines
Deal found 3/12![American Airlines logo]()
$373
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:37 pm
SAN
- SAV
2 stops10h 39m
United Airlines
Tue 4/145:04 pm
SAV
- SAN
1 stop8h 55m
United Airlines
Deal found 3/12![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/712:53 pm
SAN
- CHS
1 stop8h 31m
American Airlines
Tue 4/147:00 am
CHS
- SAN
1 stop8h 13m
American Airlines
Deal found 3/15![American Airlines logo]()
$377
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/810:30 pm
SAN
- MYR
1 stop8h 48m
United Airlines
Wed 4/1511:00 am
MYR
- SAN
2 stops12h 12m
United Airlines
Deal found 3/12![United Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:52 am
SAN
- CHS
1 stop7h 33m
United Airlines
Tue 4/215:00 pm
CHS
- SAN
1 stop8h 59m
United Airlines
Deal found 3/12![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:45 am
SAN
- CHS
2 stops10h 15m
Southwest
Tue 4/216:40 am
CHS
- SAN
2 stops9h 15m
Southwest
Deal found 3/12![Southwest logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/189:45 pm
SAN
- CAE
1 stop9h 28m
American Airlines
Tue 4/213:41 pm
CAE
- SAN
1 stop7h 28m
American Airlines
Deal found 3/15![American Airlines logo]()
$369
This flygcity.se deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flygcity.se is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/209:15 pm
SAN
- SAV
1 stop9h 40m
JetBlue
Tue 4/2810:45 am
SAV
- SAN
1 stop12h 20m
JetBlue
Deal found 3/12![JetBlue logo]()
$299
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/209:40 pm
SAN
- SAV
1 stop10h 15m
Southwest
Tue 4/282:20 pm
SAV
- SAN
2 stops9h 40m
Southwest
Deal found 3/12![Southwest logo]()
$378
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2110:30 pm
SAN
- MYR
1 stop8h 48m
United Airlines
Tue 4/283:15 pm
MYR
- SAN
1 stop10h 44m
United Airlines
Deal found 3/11![United Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:15 am
SAN
- GSP
1 stop7h 06m
American Airlines
Wed 4/294:28 pm
GSP
- SAN
1 stop7h 22m
American Airlines
Deal found 3/12![American Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:53 pm
SAN
- SAV
1 stop8h 06m
American Airlines
Wed 5/137:00 am
SAV
- SAN
1 stop10h 05m
American Airlines
Deal found 3/12![American Airlines logo]()
$367
One-way flights from San Diego to South CarolinaSearch for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 17, 2026.
Search for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:00 am
SAN
- CLT
1 stop7h 54m
Frontier
Deal found 3/16![Frontier logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:12 pm
SAN
- CLT
1 stop27h 42m
Frontier
Deal found 3/13![Frontier logo]()
$93
This Frontier deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:25 am
SAN
- CLT
1 stop7h 00m
Frontier
Deal found 3/12![Frontier logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:25 am
SAN
- CLT
2 stops26h 20m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:37 am
SAN
- CLT
1 stop27h 48m
Frontier
Deal found 3/12![Frontier logo]()
$115
This Mytrip deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:25 pm
SAN
- CLT
1 stop25h 31m
Frontier
Deal found 3/13![Frontier logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:25 am
SAN
- CLT
2 stops23h 45m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:25 am
SAN
- CLT
2 stops26h 40m
Frontier
Deal found 3/12![Frontier logo]()
$119
This Frontier deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:25 am
SAN
- CLT
1 stop7h 58m
Frontier
Deal found 3/14![Frontier logo]()
$125
This Trip.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:25 am
SAN
- CLT
1 stop8h 10m
Frontier
Deal found 3/12![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:20 am
SAN
- SAV
2 stops36h 28m
Multiple Airlines
Deal found 3/14![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:15 am
SAN
- CHS
3 stops24h 53m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$157
Find flight deals from San Diego to South Carolina
Keep the following information in mind while searching for San Diego to South Carolina flight deals. Data was last updated March 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (flygcity.se) |
One-way from | $91 (Kiwi.com) |
Popular in | March |
Cheapest in | October |
Average price | $566 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoSavannah
SAN - SAV
SANSAV
San Diego
Wed 5/13
12:55 pm-11:59 pm
1 stop8h 04m
Savannah/Hilton Head
Sat 5/16
8:08 am-3:33 pm
1 stop10h 25m
$373
San DiegoSavannah
SAN - SAV
SANSAV
San Diego
Mon 4/20
9:40 pm-10:55 am
1 stop10h 15m
Savannah/Hilton Head
Tue 4/28
2:20 pm-9:00 pm
2 stops9h 40m
$378
San DiegoSavannah
SAN - SAV
SANSAV
San Diego
Wed 5/13
7:25 am-8:00 pm
2 stops9h 35m
Savannah/Hilton Head
Sat 5/16
5:20 pm-11:25 pm
2 stops9h 05m
$383
San DiegoAugusta
SAN - AGS
SANAGS
San Diego
Sat 5/9
12:17 pm-10:56 pm
1 stop7h 39m
Augusta Bush Field
Tue 5/12
5:08 pm-10:00 pm
1 stop7h 52m
$392
San DiegoHilton Head Island
SAN - HHH
SANHHH
San Diego
Sat 8/29
10:30 pm-3:20 pm
2 stops13h 50m
Hilton Head Island
Sat 9/5
12:00 pm-6:23 pm
1 stop9h 23m
$394
San DiegoColumbia
SAN - CAE
SANCAE
San Diego
Wed 4/22
9:45 pm-10:14 am
1 stop9h 29m
Columbia Metropolitan
Sat 4/25
10:50 am-6:53 pm
2 stops11h 03m
$394
San DiegoSavannah
SAN - SAV
SANSAV
San Diego
Sat 4/25
6:30 am-5:00 pm
1 stop7h 30m
Savannah/Hilton Head
Sat 4/25
6:00 pm-11:15 pm
1 stop8h 15m
$398
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Thu 4/23
10:30 pm-9:09 am
1 stop7h 39m
Greenville
Mon 4/27
6:26 pm-11:06 pm
1 stop7h 40m
$399
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Thu 6/4
6:35 am-7:10 pm
1 stop9h 35m
Charlotte Douglas
Mon 6/8
7:05 pm-11:25 pm
1 stop7h 20m
$399
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Wed 4/15
8:40 am-8:55 pm
2 stops9h 15m
Charlotte Douglas
Mon 4/20
6:15 am-12:40 pm
2 stops9h 25m
$399
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Diego to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Diego with our price prediction graph.
SAN-CHS
SAN-CLT
SAN-SAV
SAN-MYR
SAN-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to South Carolina
SAN-USSC
SAN-CHS
SAN-CLT
SAN-SAV
SAN-MYR
What is the cheapest month to book a flight from San Diego to South Carolina?
Currently, January is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $134). Flying from San Diego to South Carolina in February is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to SC?
Find hourly flight availability from San Diego to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 17, 2026.
It’s optimal to fly from San Diego to South Carolina at noon. By choosing this option you can save up to 74% on the cost of your flight, compared to a flight in the evening.
What is the cheapest day to fly from San Diego to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from San Diego to South Carolina. Price data was last updated on March 30, 2025.
Travelers seeking maximum savings on their San Diego to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from San Diego to South Carolina
Explore weekly flight availability from San Diego to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 17, 2026.
The most flights from SAN to USSC are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 17, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from San Diego to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Diego to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from San Diego to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and South Carolina flights
Browse other San Diego and South Carolina flight options. Last updated on March 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to South Carolina flights
Consider these flights traveling from San Diego to South Carolina.
Top 5 airlines flying from San Diego to South Carolina
Discover the top 5 airlines that operate flights from San Diego to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$126 | Average$252 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$233 | Average$484 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$510 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$264 | Average$436 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$378 | Average$492 | FlexibilityNo cancel fee | On-time63% |