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South Carolina

$69+ Cheap flights from San Diego (SAN) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — CHS
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Find flight deals from San Diego to South Carolina

Cheapest flights from San Diego to South Carolina
Explore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This Delta deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:25 amSAN - CHS
1 stop6h 14mDelta
Thu 1/16:00 amCHS - SAN
1 stop7h 15mDelta
Deal found 11/17$307
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/61:12 pmSAN - CHS
1 stop21h 49mMultiple Airlines
Mon 12/87:05 amCHS - SAN
2 stops11h 57mMultiple Airlines
Deal found 11/18$328
This Expedia deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/159:37 pmSAN - CHS
2 stops17h 47mMultiple Airlines
Thu 12/183:06 pmCHS - SAN
1 stop9h 59mMultiple Airlines
Deal found 11/17$329
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:21 amSAN - CHS
1 stop8h 03mAmerican Airlines
Mon 1/53:38 pmCHS - SAN
1 stop7h 37mAmerican Airlines
Deal found 11/19$332
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/31:12 pmSAN - CHS
1 stop21h 49mMultiple Airlines
Mon 12/157:05 amCHS - SAN
2 stops11h 57mMultiple Airlines
Deal found 11/18$339
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:34 amSAN - CLT
1 stop25h 48mFrontier
Wed 12/315:14 pmCLT - SAN
1 stop9h 45mFrontier
Deal found 11/18$342
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/31:12 pmSAN - CHS
1 stop21h 49mMultiple Airlines
Thu 12/117:05 amCHS - SAN
2 stops39h 10mMultiple Airlines
Deal found 11/18$343
This Alaska Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:25 pmSAN - CHS
1 stop22h 59mAlaska Airlines
Mon 1/56:57 pmCHS - SAN
2 stops20h 59mAlaska Airlines
Deal found 11/19$346
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:25 amSAN - CLT
1 stop7h 17mFrontier
Thu 1/19:24 amCLT - SAN
2 stops30h 51mFrontier
Deal found 11/18$346
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:34 amSAN - CLT
1 stop25h 48mFrontier
Tue 12/2310:52 amCLT - SAN
2 stops40h 07mFrontier
Deal found 11/18$347
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:34 amSAN - CLT
2 stops24h 16mFrontier
Tue 12/2312:17 pmCLT - SAN
1 stop9h 58mFrontier
Deal found 11/18$348
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/181:36 pmSAN - CAE
1 stop7h 31mAmerican Airlines
Mon 12/223:37 pmCAE - SAN
1 stop7h 38mAmerican Airlines
Deal found 11/20$349

Cheap flight deals from San Diego to South Carolina

Keep the following information in mind while searching for San Diego to South Carolina flight deals. Data was last updated November 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$269
(JetBlue)

One-way from

$69
(Priceline)

Popular in

December

Cheapest in

October

Average price

$482
Provider with most accurate pricing for San Diego-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Diego-Myrtle Beach Intl flights.
Search Deals
From San Diego to South Carolina
Search Deals
One-way flight from San Diego to South Carolina
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($37 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.

Fly from

San Diego

Fly to

South Carolina

Route

Depart

Return

Price

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Mon 1/12

9:30 pm-12:13 pm

1 stop11h 43m

Charleston

Wed 1/14

1:10 pm-8:20 pm

1 stop10h 10m

$269

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Fri 1/16

9:30 pm-12:13 pm

1 stop11h 43m

Charleston

Wed 1/21

1:10 pm-8:20 pm

1 stop10h 10m

$275

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Fri 1/16

9:30 pm-12:13 pm

1 stop11h 43m

Charleston

Mon 1/19

10:10 am-7:50 pm

1 stop12h 40m

$275

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Fri 2/6

9:30 pm-12:13 pm

1 stop11h 43m

Charleston

Mon 2/9

10:10 am-7:50 pm

1 stop12h 40m

$275

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Wed 1/14

6:15 am-6:22 pm

1 stop9h 07m

Charleston

Wed 1/21

7:22 pm-10:07 am

1 stop17h 45m

$296

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Thu 1/15

6:45 am-6:00 pm

1 stop8h 15m

Charleston

Tue 1/20

4:50 pm-11:05 pm

1 stop9h 15m

$297

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Fri 2/6

6:15 am-6:22 pm

1 stop9h 07m

Charleston

Mon 2/9

7:22 pm-4:02 pm

2 stops23h 40m

$326

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Thu 1/8

9:00 am-11:44 pm

2 stops11h 44m

Charleston

Wed 1/14

10:15 am-3:36 pm

1 stop8h 21m

$332

San DiegoMyrtle Beach

SAN - MYR

SANMYR

San Diego

Thu 2/5

12:40 pm-11:15 pm

1 stop7h 35m

Myrtle Beach Intl

Mon 2/9

1:53 pm-8:36 pm

1 stop9h 43m

$335

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Thu 1/8

5:00 pm-6:22 pm

2 stops22h 22m

Charleston

Sun 1/11

7:22 pm-10:07 am

1 stop17h 45m

$336

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/20

Showing 1-10 of 60 results
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Best time to book a flight from San Diego to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to South Carolina

What is the cheapest month to book a flight from San Diego to South Carolina?

Currently, September is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $154). Flying from San Diego to South Carolina in December is currently the most expensive (average of $320). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SC?

Find hourly flight availability from San Diego to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

It’s optimal to fly from San Diego to South Carolina at noon. By choosing this option you can save up to 65% on the cost of your flight, compared to a flight in the afternoon.

What is the cheapest day to fly from San Diego to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from San Diego to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Diego to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 20, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from San Diego to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,251 reviews

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,251 reviews
Southwest
8.0
Very good
4,251 reviews

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,002 reviews
Southwest
8.0
Very good
4,251 reviews

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
9,028 reviews
Southwest
8.0
Very good
4,251 reviews

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,047 reviews
Southwest
8.0
Very good
4,251 reviews

Food

7.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from San Diego to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to South Carolina?

    San Diego (SAN), located 2.6 mi from the city center, is the airport you fly out of when you book flights from San Diego to South Carolina.

  • How long is the flight from San Diego to South Carolina?

    Departing from San Diego to South Carolina will take you 7h 35m. There are 2199 mi between San Diego and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from San Diego to South Carolina one-way?

    $73 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Delta and Breeze Airways, with prices starting from $155 and $156, respectively.

  • What are the most popular routes from San Diego to South Carolina?

    When deciding which route to take from San Diego to South Carolina consider San Diego - Charlotte Douglas, San Diego - Charleston or San Diego - Savannah/Hilton Head as they are the most popular.

  • Can I find deals for flights from San Diego to South Carolina that include hotel bookings?

    Yes. In addition to deals on San Diego to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to South Carolina.

  • Can I find deals for business class flights from San Diego to South Carolina?

    Yes. Cheapflights offers flight deals from San Diego to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $154). Flying from San Diego to South Carolina in December is currently the most expensive (average of $320). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Diego to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from San Diego to South Carolina

Discover the top 4 airlines that operate flights from San Diego to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$233Average$489FlexibilityNo cancel feeOn-time69%
DeltaCheapest$249Average$443FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$264Average$477FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$362Average$468FlexibilityNo cancel feeOn-time63%

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