South Carolina

$84+ Cheap flights from San Diego (SAN) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — CHS
Feb 28 — Mar 71
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Cheap flight deals from San Diego to South Carolina

Cheapest flights from San Diego to South Carolina
Explore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Frontier deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:25 am
SAN
-
CLT
1 stop6h 53m
Frontier
Mon 3/25:13 pm
CLT
-
SAN
1 stop9h 55m
Frontier
Deal found 1/26$168
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:11 am
SAN
-
CLT
1 stop30h 07m
Frontier
Sun 3/13:39 pm
CLT
-
SAN
2 stops30h 56m
Frontier
Deal found 1/26$180
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:11 am
SAN
-
CLT
1 stop30h 07m
Frontier
Mon 3/28:38 pm
CLT
-
SAN
2 stops26h 46m
Frontier
Deal found 1/26$182
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:25 am
SAN
-
CLT
2 stops24h 07m
Frontier
Sun 3/15:03 pm
CLT
-
SAN
1 stop10h 05m
Frontier
Deal found 1/26$199
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:11 am
SAN
-
CLT
1 stop30h 07m
Frontier
Sat 2/2810:16 am
CLT
-
SAN
2 stops16h 52m
Frontier
Deal found 1/26$201
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:35 am
SAN
-
CLT
2 stops30h 13m
Frontier
Sun 3/15:03 pm
CLT
-
SAN
1 stop10h 05m
Frontier
Deal found 1/26$204
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:59 am
SAN
-
CLT
1 stop27h 49m
Frontier
Tue 3/107:48 pm
CLT
-
SAN
2 stops28h 26m
Frontier
Deal found 1/26$207
This Frontier deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:25 am
SAN
-
CLT
1 stop9h 29m
Frontier
Sun 4/127:49 pm
CLT
-
SAN
1 stop7h 13m
Frontier
Deal found 1/26$215
This Frontier deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:25 am
SAN
-
CLT
1 stop6h 53m
Frontier
Mon 3/97:43 pm
CLT
-
SAN
1 stop7h 25m
Frontier
Deal found 1/27$218
This Rumbo deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/289:10 pm
SAN
-
CHS
1 stop10h 48m
JetBlue
Fri 3/612:36 pm
CHS
-
SAN
1 stop10h 22m
JetBlue
Deal found 1/29$242
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/107:00 am
SAN
-
CHS
1 stop8h 04m
United Airlines
Tue 3/178:15 am
CHS
-
SAN
1 stop10h 24m
United Airlines
Deal found 1/28$281
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/107:00 am
SAN
-
CHS
1 stop11h 24m
Delta
Sat 3/146:00 am
CHS
-
SAN
1 stop17h 48m
Delta
Deal found 1/29$310

Find flight deals from San Diego to South Carolina

Keep the following information in mind while searching for San Diego to South Carolina flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$168
(Frontier)

One-way from

$84
(Frontier)

Popular in

December

Cheapest in

October

Average price

$377
Provider with most accurate pricing for San Diego-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for San Diego-Myrtle Beach Intl flights.
From San Diego to South Carolina
One-way flight from San Diego to South Carolina
Highest demand for flights based on searches. 5% potential increase in price ($24 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Average for round-trip flights in January 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.

Fly from

San Diego

Fly to

South Carolina

Route

Depart

Return

Price

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Tue 3/10

7:00 am-6:04 pm

1 stop8h 04m

Charleston

Tue 3/17

8:15 am-3:39 pm

1 stop10h 24m

$281

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Thu 4/23

10:30 pm-10:21 am

1 stop8h 51m

Savannah/Hilton Head

Tue 4/28

4:59 pm-10:59 pm

1 stop9h 00m

$318

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Mon 3/9

10:25 pm-9:24 pm

1 stop19h 59m

Charleston

Sat 3/14

6:00 am-8:48 pm

1 stop17h 48m

$323

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Thu 5/14

2:00 pm-12:04 am

1 stop7h 04m

Savannah/Hilton Head

Sun 5/17

6:50 pm-10:58 pm

1 stop7h 08m

$323

San DiegoColumbia

SAN - CAE

SANCAE

San Diego

Wed 3/11

9:55 pm-9:18 am

1 stop8h 23m

Columbia Metropolitan

Tue 3/31

5:34 am-9:52 am

1 stop7h 18m

$329

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Wed 4/1

1:30 pm-10:25 pm

1 stop5h 55m

Charleston

Mon 4/6

6:40 pm-10:40 pm

1 stop7h 00m

$340

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Mon 2/23

12:16 pm-9:58 pm

1 stop6h 42m

Charleston

Thu 2/26

10:00 am-5:29 pm

2 stops10h 29m

$342

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Tue 3/3

9:10 pm-10:57 am

1 stop10h 47m

Charleston

Fri 3/6

12:36 pm-7:58 pm

1 stop10h 22m

$343

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Mon 3/9

6:20 am-4:44 pm

1 stop7h 24m

Charleston

Thu 3/12

2:43 pm-7:09 pm

1 stop7h 26m

$343

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Mon 3/9

7:00 am-6:04 pm

1 stop8h 04m

Charleston

Fri 3/13

8:15 am-3:39 pm

1 stop10h 24m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 60 results
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Best time to book a flight from San Diego to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to South Carolina

What is the cheapest month to book a flight from San Diego to South Carolina?

Currently, January is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $149). Flying from San Diego to South Carolina in December is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SC?

Find hourly flight availability from San Diego to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

It’s optimal to fly from San Diego to South Carolina at noon. By choosing this option you can save up to 74% on the cost of your flight, compared to a flight in the evening.

What is the cheapest day to fly from San Diego to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from San Diego to South Carolina. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their San Diego to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 29, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from San Diego to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from San Diego to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Diego to South Carolina?

    San Diego (SAN), located 2.6 mi from the city center, is the airport you fly out of when you book flights from San Diego to South Carolina.

  • How long is the flight from San Diego to South Carolina?

    Departing from San Diego to South Carolina will take you 5h 55m. There are 2145 mi between San Diego and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from San Diego to South Carolina one-way?

    $108 is the cheapest one-way deal found within the past few days, from Hawaiian Airlines. You may also be able to find cheap deals on Alaska Airlines and American Airlines, with prices starting from $119 and $123, respectively.

  • What are the most popular routes from San Diego to South Carolina?

  • Can I find deals for flights from San Diego to South Carolina that include hotel bookings?

    Yes. In addition to deals on San Diego to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to South Carolina.

  • Can I find deals for business class flights from San Diego to South Carolina?

    Yes. Cheapflights offers flight deals from San Diego to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to South Carolina?

    Currently, January is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $149). Flying from San Diego to South Carolina in December is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Diego to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from San Diego to South Carolina

Discover the top 5 airlines that operate flights from San Diego to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$126Average$252FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$199Average$499FlexibilityNo cancel feeOn-time69%
DeltaCheapest$213Average$428FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$506FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$344Average$475FlexibilityNo cancel feeOn-time63%

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