$149+ Cheap flights from San Diego (SAN) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — CHS
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to South Carolina with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Diego to South CarolinaExplore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:55 am -
1 stop5h 55m
Thu 12/107:05 am -
1 stop6h 30m
Deal found 10/26![Southwest logo]()
$265
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:05 am -
2 stops8h 05m
Sat 12/1210:50 am -
2 stops8h 00m
Deal found 10/26![Southwest logo]()
$275
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:30 pm -
1 stop8h 37m
Thu 12/106:57 pm -
1 stop7h 41m
Deal found 10/27![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:30 pm -
1 stop8h 17m
Thu 12/33:44 pm -
1 stop8h 35m
Deal found 10/26![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:30 pm -
1 stop8h 45m
Wed 12/92:04 pm -
1 stop8h 57m
Deal found 10/26![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:41 pm -
2 stops12h 22m
Sat 12/56:00 am -
1 stop8h 27m
Deal found 10/29![United Airlines logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:51 pm -
2 stops23h 45m
Sun 12/133:00 pm -
1 stop24h 00m
Deal found 10/29![Multiple Airlines logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:45 pm -
1 stop30h 51m
Fri 11/136:10 am -
2 stops15h 28m
Deal found 10/25![Multiple Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:13 am -
1 stop8h 07m
Sat 12/57:00 am -
1 stop8h 21m
Deal found 10/25![American Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:35 pm -
1 stop10h 50m
Wed 12/26:45 pm -
1 stop7h 25m
Deal found 10/28![Southwest logo]()
$347
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:05 am -
1 stop7h 20m
Wed 1/66:40 pm -
1 stop7h 20m
Deal found 10/29![Southwest logo]()
$351
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:15 am -
1 stop9h 17m
Fri 1/17:00 am -
1 stop7h 02m
Deal found 10/27![American Airlines logo]()
$353
Best flights from San Diego to South CarolinaDiscover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:30 pm -
1 stop8h 37m
Thu 12/106:57 pm -
1 stop7h 41m
Deal found 10/27![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:35 pm -
1 stop10h 50m
Wed 12/27:05 am -
2 stops9h 25m
Deal found 10/28![Southwest logo]()
$373
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:30 pm -
1 stop9h 51m
Tue 11/178:30 am -
2 stops9h 25m
Deal found 10/29![United Airlines logo]()
$386
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/187:00 am -
1 stop8h 55m
Thu 3/47:26 pm -
1 stop7h 32m
Deal found 10/26![American Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/112:22 pm -
1 stop6h 31m
Thu 1/147:13 am -
1 stop10h 19m
Deal found 10/25![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:30 pm -
1 stop8h 45m
Wed 12/92:04 pm -
1 stop8h 57m
Deal found 10/26![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:55 am -
2 stops7h 45m
Sun 12/134:30 pm -
2 stops9h 10m
Deal found 10/29![Southwest logo]()
$383
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:30 pm -
1 stop8h 17m
Thu 12/37:25 pm -
1 stop7h 13m
Deal found 10/28![Delta logo]()
$338
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/166:40 am -
2 stops9h 30m
Mon 4/197:00 pm -
1 stop7h 25m
Deal found 10/27![Southwest logo]()
$386
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/177:41 pm -
2 stops12h 05m
Sat 1/2311:27 am -
2 stops12h 15m
Deal found 10/26![United Airlines logo]()
$425
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:30 am -
2 stops10h 05m
Thu 1/76:40 pm -
1 stop7h 20m
Deal found 10/29![Southwest logo]()
$386
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/211:40 am -
1 stop7h 18m
Thu 3/45:05 pm -
1 stop8h 58m
Deal found 10/29![Delta logo]()
$351
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/28:40 am -
2 stops9h 23m
Wed 2/310:40 am -
2 stops13h 54m
Deal found 10/29![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/27:20 am -
1 stop7h 10m
Thu 3/43:07 pm -
1 stop9h 18m
Deal found 10/26![American Airlines logo]()
$515
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:25 am -
1 stop9h 00m
Wed 1/612:35 pm -
1 stop11h 12m
Deal found 10/27![Delta logo]()
$363
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1311:00 am -
1 stop6h 15m
Sun 11/155:30 am -
2 stops10h 00m
Deal found 10/28![Southwest logo]()
$406
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:41 pm -
3 stops15h 39m
Sat 12/52:57 pm -
2 stops12h 22m
Deal found 10/29![United Airlines logo]()
$471
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/196:35 am -
2 stops13h 05m
Thu 12/311:30 pm -
1 stop10h 30m
Deal found 10/28![Southwest logo]()
$418
This KAYAK deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:05 pm -
1 stop10h 39m
Thu 12/105:22 pm -
1 stop9h 35m
Deal found 10/26![Delta logo]()
$382
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:08 pm -
1 stop8h 46m
Wed 12/26:24 am -
1 stop7h 39m
Deal found 10/29![American Airlines logo]()
$565
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/611:26 am -
1 stop7h 33m
Thu 1/79:45 am -
1 stop8h 33m
Deal found 10/29![United Airlines logo]()
$481
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/177:25 am -
1 stop8h 45m
Sat 1/238:15 am -
2 stops10h 50m
Deal found 10/25![Southwest logo]()
$419
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:08 pm -
1 stop8h 46m
Thu 12/35:05 am -
1 stop8h 59m
Deal found 10/29![American Airlines logo]()
$600
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/226:20 am -
1 stop8h 37m
Mon 4/262:59 pm -
1 stop6h 43m
Deal found 10/28![Delta logo]()
$419
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/286:20 am -
2 stops14h 14m
Mon 2/110:40 am -
2 stops12h 28m
Deal found 10/29![United Airlines logo]()
$525
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/287:30 am -
2 stops11h 40m
Mon 2/15:25 pm -
1 stop9h 08m
Deal found 10/26![Delta logo]()
$420
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:45 pm -
1 stop12h 05m
Sat 12/56:24 am -
1 stop9h 44m
Deal found 10/25![American Airlines logo]()
$625
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/308:00 am -
1 stop8h 24m
Wed 2/32:26 pm -
1 stop11h 11m
Deal found 10/28![United Airlines logo]()
$549
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:20 am -
1 stop7h 50m
Thu 11/195:35 am -
1 stop7h 14m
Deal found 10/29![Delta logo]()
$459
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/610:22 pm -
1 stop9h 24m
Sat 1/911:27 am -
2 stops12h 15m
Deal found 10/25![United Airlines logo]()
$563
Last-minute flights from San Diego to South CarolinaDiscover last-minute flight deals from San Diego to South Carolina. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to South Carolina. Data last updated October 30, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:45 pm -
1 stop30h 51m
Fri 11/136:10 am -
2 stops15h 28m
Deal found 10/25![Multiple Airlines logo]()
$340
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:50 pm -
1 stop7h 53m
Mon 11/167:04 pm -
1 stop7h 28m
Deal found 10/26![Delta logo]()
$353
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:10 pm -
1 stop9h 30m
Sat 11/146:00 am -
1 stop6h 49m
Deal found 10/27![Delta logo]()
$403
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:30 pm -
1 stop9h 51m
Tue 11/178:30 am -
2 stops9h 25m
Deal found 10/29![United Airlines logo]()
$386
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:30 pm -
1 stop8h 17m
Thu 12/33:44 pm -
1 stop8h 35m
Deal found 10/26![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:55 am -
2 stops7h 45m
Wed 11/259:15 pm -
1 stop7h 15m
Deal found 10/29![Southwest logo]()
$358
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/219:45 pm -
1 stop9h 21m
Sat 12/56:00 am -
2 stops10h 13m
Deal found 10/29![United Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:35 pm -
1 stop6h 54m
Sat 12/57:00 am -
1 stop8h 21m
Deal found 10/29![American Airlines logo]()
$402
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:40 pm -
1 stop6h 55m
Wed 12/26:25 pm -
1 stop7h 45m
Deal found 10/28![Southwest logo]()
$392
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:39 pm -
1 stop9h 27m
Wed 12/24:18 pm -
1 stop9h 12m
Deal found 10/28![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:35 pm -
1 stop10h 50m
Wed 12/26:45 pm -
1 stop7h 25m
Deal found 10/28![Southwest logo]()
$347
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:20 am -
1 stop7h 09m
Thu 12/34:18 pm -
1 stop8h 01m
Deal found 10/28![Delta logo]()
$325
One-way flights from San Diego to South CarolinaSearch for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:39 am -
1 stop6h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Delta logo]()
$149
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:30 pm -
1 stop8h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Delta logo]()
$160
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/97:25 am -
1 stop9h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Southwest logo]()
$160
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:15 am -
1 stop8h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Delta logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:32 pm -
3 stops44h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/108:57 pm -
3 stops32h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:30 am -
2 stops53h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/98:37 pm -
3 stops38h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$171
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1210:02 pm -
1 stop7h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![American Airlines logo]()
$173
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/410:35 pm -
1 stop12h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Southwest logo]()
$176
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:50 am -
1 stop7h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![United Airlines logo]()
$180
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1110:15 am -
1 stop9h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Southwest logo]()
$183
Find flight deals from San Diego to South Carolina
Keep the following information in mind while searching for San Diego to South Carolina flight deals. Data was last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $265 (Southwest) |
One-way from | $149 (Delta) |
Popular in | August |
Cheapest in | January |
Average price | $439 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoMyrtle Beach
SAN San Diego - MYR Myrtle Beach Intl
SANMYR
San Diego
Wed 12/2
10:30 pm-10:07 am
1 stop8h 37m
Myrtle Beach Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$160
San DiegoCharleston
SAN San Diego - CHS Charleston
SANCHS
San Diego
Sat 12/12
6:15 am-6:02 pm
1 stop8h 47m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$163
San DiegoGreenville
SAN San Diego - GSP Greenville
SANGSP
San Diego
Tue 2/9
7:10 am-6:15 pm
2 stops8h 05m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$165
San DiegoCharleston
SAN San Diego - CHS Charleston
SANCHS
San Diego
Sat 4/10
7:00 am-6:35 pm
1 stop8h 35m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$173
San DiegoMyrtle Beach
SAN San Diego - MYR Myrtle Beach Intl
SANMYR
San Diego
Wed 12/2
11:16 am-11:44 am
2 stops45h 28m
Myrtle Beach Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$176
San DiegoGreenville
SAN San Diego - GSP Greenville
SANGSP
San Diego
Mon 1/4
10:35 pm-2:10 pm
1 stop12h 35m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$176
San DiegoGreenville
SAN San Diego - GSP Greenville
SANGSP
San Diego
Sun 12/6
6:50 am-4:53 pm
1 stop7h 03m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$180
San DiegoGreenville
SAN San Diego - GSP Greenville
SANGSP
San Diego
Thu 11/19
11:39 am-9:33 pm
1 stop6h 54m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$190
San DiegoCharleston
SAN San Diego - CHS Charleston
SANCHS
San Diego
Mon 3/8
9:40 pm-8:40 am
1 stop8h 00m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$191
San DiegoCharleston
SAN San Diego - CHS Charleston
SANCHS
San Diego
Mon 11/9
9:50 pm-8:43 am
1 stop7h 53m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$191
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Diego to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Diego with our price prediction graph.
SAN-MYR
SAN-GSP
SAN-CAE
SAN-CHS
SAN-HHH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to South Carolina
SAN-USSC
SAN-MYR
SAN-GSP
SAN-CAE
SAN-CHS
What is the cheapest month to book a flight from San Diego to South Carolina?
Currently, January is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $396). Flying from San Diego to South Carolina in March is currently the most expensive (average of $558). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to South Carolina?
Airfare is below average for this route at the moment.
San Diego to South Carolina flights typically cost between $462 and $725 in December.The cheapest round-trip price found within the last 5 days was $325 on Delta (Dec 1-Dec 9).
How far ahead should I book a flight from San Diego to South Carolina?
The price you pay for your flight from San Diego to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 50 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 30, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from San Diego to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.4
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from San Diego to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to South Carolina
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Complete your trip
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San Diego and South Carolina flights
Browse other San Diego and South Carolina flight options. Last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to South Carolina flights
Consider these flights traveling from San Diego to South Carolina.
Top 5 airlines flying from San Diego to South Carolina
Discover the top 5 airlines that operate flights from San Diego to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$134 | Average$282 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$298 | Average$499 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$298 | Average$558 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$304 | Average$501 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$326 | Average$486 | FlexibilityNo cancel fee | On-time69% |