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South Carolina

$109+ Cheap flights from San Diego (SAN) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — CHS
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from San Diego to South Carolina

Keep the following information in mind while searching for San Diego to South Carolina flight deals. Data was last updated September 16, 2025.

Round-trip from

$275
(JetBlue)

One-way from

$109
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$436
From San Diego to South Carolina
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One-way flight from San Diego to South Carolina
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Highest demand for flights based on searches. 6% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Diego to South Carolina

Cheapest flights from San Diego to South Carolina
Explore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This JetBlue deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/19:20 pmSAN - CHS
1 stop11h 08mJetBlue
Tue 11/46:05 amCHS - SAN
1 stop9h 43mJetBlue
Deal found 9/15$275
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/126:41 amSAN - CLT
2 stops23h 34mFrontier
Mon 10/275:34 pmCLT - SAN
1 stop9h 16mFrontier
Deal found 9/16$278
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/212:04 pmSAN - CLT
2 stops17h 07mFrontier
Sun 10/510:20 pmCLT - SAN
2 stops15h 49mFrontier
Deal found 9/16$282
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2512:04 pmSAN - CLT
2 stops20h 18mFrontier
Mon 9/2911:47 amCLT - SAN
1 stop9h 07mFrontier
Deal found 9/15$285
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/139:03 pmSAN - CLT
2 stops37h 16mFrontier
Mon 10/205:34 pmCLT - SAN
1 stop9h 16mFrontier
Deal found 9/13$288
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:27 pmSAN - CLT
1 stop13h 55mFrontier
Mon 10/65:20 pmCLT - SAN
1 stop9h 33mFrontier
Deal found 9/16$289
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/189:03 pmSAN - CLT
1 stop16h 40mFrontier
Thu 9/251:11 pmCLT - SAN
1 stop7h 31mFrontier
Deal found 9/15$291
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:35 amSAN - CLT
2 stops11h 50mFrontier
Thu 10/25:20 pmCLT - SAN
1 stop9h 33mFrontier
Deal found 9/15$294
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:35 amSAN - CLT
1 stop7h 08mFrontier
Sun 9/2812:07 pmCLT - SAN
1 stop7h 35mFrontier
Deal found 9/14$297
This JetBlue deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:31 pmSAN - SAV
1 stop12h 01mJetBlue
Mon 12/812:20 pmSAV - SAN
1 stop10h 01mJetBlue
Deal found 9/15$297
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/112:24 pmSAN - CLT
2 stops15h 44mFrontier
Thu 10/235:34 pmCLT - SAN
1 stop9h 16mFrontier
Deal found 9/16$298
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/66:35 amSAN - CLT
2 stops11h 50mFrontier
Fri 10/105:34 pmCLT - SAN
1 stop9h 16mFrontier
Deal found 9/16$299

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.

Fly from

San Diego

Fly to

South Carolina

Route

Depart

Return

Price

San DiegoCharleston

SAN - CHS

SANCHS

San Diego

Sat 11/1

9:20 pm-11:28 am

1 stop11h 08m

Charleston

Tue 11/4

6:05 am-12:48 pm

1 stop9h 43m

$275

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Sat 11/8

9:05 pm-10:34 am

1 stop10h 29m

Savannah/Hilton Head

Wed 11/12

11:19 am-7:46 pm

1 stop11h 27m

$297

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Wed 10/22

2:05 pm-11:58 pm

1 stop6h 53m

Savannah/Hilton Head

Mon 10/27

3:33 pm-9:20 pm

1 stop8h 47m

$307

San DiegoHilton Head Island

SAN - HHH

SANHHH

San Diego

Tue 3/10

11:00 pm-10:24 am

1 stop8h 24m

Hilton Head Island

Tue 3/17

4:10 pm-8:18 pm

1 stop7h 08m

$309

San DiegoColumbia

SAN - CAE

SANCAE

San Diego

Thu 10/23

12:54 pm-12:06 am

1 stop8h 12m

Columbia Metropolitan

Mon 10/27

7:30 pm-11:40 pm

1 stop7h 10m

$309

San DiegoColumbia

SAN - CAE

SANCAE

San Diego

Wed 11/12

6:15 am-4:54 pm

1 stop7h 39m

Columbia Metropolitan

Wed 11/19

5:37 am-9:57 am

1 stop7h 20m

$309

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Sat 11/8

10:09 am-9:39 pm

2 stops8h 30m

Savannah/Hilton Head

Wed 11/12

1:18 pm-7:43 pm

1 stop9h 25m

$312

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Thu 11/13

12:11 pm-10:37 pm

1 stop7h 26m

Savannah/Hilton Head

Mon 11/17

3:10 pm-9:13 pm

1 stop9h 03m

$317

San DiegoAugusta

SAN - AGS

SANAGS

San Diego

Wed 11/12

12:43 pm-10:25 pm

1 stop6h 42m

Augusta Bush Field

Sat 11/15

4:14 pm-8:20 pm

1 stop7h 06m

$317

San DiegoSavannah

SAN - SAV

SANSAV

San Diego

Sat 12/13

12:43 pm-10:30 pm

1 stop6h 47m

Savannah/Hilton Head

Thu 1/1

7:38 pm-11:59 pm

1 stop7h 21m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 60 results
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Best time to book a flight from San Diego to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to South Carolina

What is the cheapest month to book a flight from San Diego to South Carolina?

Currently, August is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $217). Flying from San Diego to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SC?

Find hourly flight availability from San Diego to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from San Diego to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 16, 2025.
See what other customers who have flown with Alaska Airlines, Southwest, and Delta from San Diego to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Southwest
8.0
Very good
4,242 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Delta
8.0
Very good
7,957 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
8,924 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from San Diego to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to South Carolina?

    San Diego (SAN), located 2.6 mi from the city center, is the airport you fly out of when you book flights from San Diego to South Carolina.

  • How long is the flight from San Diego to South Carolina?

    Departing from San Diego to South Carolina will take you 6h 53m. There are 2088 mi between San Diego and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from San Diego to South Carolina one-way?

    $110 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Spirit Airlines and JetBlue, with prices starting from $134 and $138, respectively.

  • What are the most popular routes from San Diego to South Carolina?

    When deciding which route to take from San Diego to South Carolina consider San Diego - Charlotte Douglas, San Diego - Charleston or San Diego - Myrtle Beach Intl as they are the most popular.

  • Can I find deals for flights from San Diego to South Carolina that include hotel bookings?

    Yes. In addition to deals on San Diego to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to South Carolina.

  • Can I find deals for business class flights from San Diego to South Carolina?

    Yes. Cheapflights offers flight deals from San Diego to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $217). Flying from San Diego to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Diego to South Carolina

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Top 6 airlines flying from San Diego to South Carolina

Discover the top 6 airlines that operate flights from San Diego to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$158Average$329FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$233Average$482FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$268Average$476FlexibilityNo cancel feeOn-time71%
DeltaCheapest$296Average$439FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$362Average$461FlexibilityNo cancel feeOn-time63%
Alaska AirlinesCheapest$465Average$784FlexibilityNo cancel feeOn-time75%

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