$118+ Cheap flights from Colorado to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Colorado to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Colorado to South Carolina
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Cheapest flights from Colorado to South CarolinaExplore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:43 am -
Nonstop3h 13m
Sun 11/84:51 pm -
Nonstop4h 03m
Deal found 9/14![Frontier logo]()
$240
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:43 am -
Nonstop3h 13m
Mon 11/162:13 pm -
1 stop9h 29m
Deal found 9/13![Frontier logo]()
$241
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:59 pm -
1 stop7h 43m
Wed 10/75:00 pm -
1 stop8h 54m
Deal found 9/14![United Airlines logo]()
$242
This Cheapflightsfares deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:39 pm -
Nonstop3h 20m
Sun 10/47:54 pm -
Nonstop3h 49m
Deal found 9/12![Frontier logo]()
$242
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:54 pm -
1 stop7h 48m
Sat 11/76:39 am -
1 stop7h 25m
Deal found 9/15![American Airlines logo]()
$243
This Expedia deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:19 pm -
1 stop11h 41m
Thu 11/194:47 pm -
Nonstop4h 03m
Deal found 9/13![Frontier logo]()
$243
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:40 am -
Nonstop3h 22m
Thu 10/229:32 am -
1 stop8h 15m
Deal found 9/14![Frontier logo]()
$244
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2811:59 pm -
1 stop22h 35m
Thu 12/35:07 pm -
Nonstop4h 01m
Deal found 9/13![Frontier logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:58 pm -
1 stop12h 34m
Mon 11/168:52 pm -
1 stop13h 32m
Deal found 9/14![Multiple Airlines logo]()
$246
This deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:21 pm -
Nonstop3h 12m
Wed 11/256:00 am -
Nonstop3h 56m
Deal found 9/14![Frontier logo]()
$246
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:59 pm -
1 stop7h 43m
Sat 10/2410:38 am -
1 stop6h 59m
Deal found 9/16![United Airlines logo]()
$247
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:19 pm -
1 stop11h 46m
Sat 10/2412:05 pm -
1 stop11h 44m
Deal found 9/16![Frontier logo]()
$247
Best flights from Colorado to South CarolinaDiscover carefully curated flight deals from Colorado to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Colorado to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:50 am -
1 stop4h 25m
Tue 11/107:05 am -
2 stops9h 05m
Deal found 9/16![Southwest logo]()
$253
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:59 pm -
1 stop7h 58m
Tue 10/206:58 pm -
1 stop5h 34m
Deal found 9/16![Delta logo]()
$262
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:20 pm -
1 stop6h 09m
Wed 11/48:36 am -
1 stop5h 45m
Deal found 9/16![United Airlines logo]()
$272
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
1 stop6h 47m
Wed 11/114:17 pm -
1 stop7h 40m
Deal found 9/16![American Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:19 pm -
2 stops38h 09m
Sat 10/248:52 am -
1 stop8h 55m
Deal found 9/11![Frontier logo]()
$361
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:40 am -
1 stop9h 45m
Wed 10/216:10 pm -
1 stop6h 30m
Deal found 9/14![Southwest logo]()
$253
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:00 am -
1 stop5h 39m
Mon 11/166:35 am -
1 stop7h 51m
Deal found 9/16![Delta logo]()
$266
This Alaska Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:30 pm -
1 stop24h 25m
Tue 11/35:58 pm -
2 stops22h 29m
Deal found 9/16![Alaska Airlines logo]()
$549
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:35 am -
2 stops8h 50m
Tue 10/67:10 pm -
1 stop5h 20m
Deal found 9/14![Southwest logo]()
$253
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:17 am -
1 stop6h 17m
Fri 10/306:45 am -
2 stops12h 42m
Deal found 9/14![Delta logo]()
$271
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am -
1 stop6h 10m
Sat 10/242:51 pm -
1 stop8h 54m
Deal found 9/15![United Airlines logo]()
$311
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:20 am -
1 stop7h 55m
Mon 10/268:55 pm -
1 stop5h 30m
Deal found 9/15![Southwest logo]()
$264
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:59 pm -
1 stop7h 43m
Tue 10/610:38 am -
1 stop8h 15m
Deal found 9/15![United Airlines logo]()
$312
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/234:07 pm -
Nonstop3h 18m
Wed 12/28:14 pm -
Nonstop3h 43m
Deal found 9/11![American Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:31 pm -
1 stop6h 14m
Mon 10/265:01 pm -
1 stop5h 15m
Deal found 9/17![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:45 am -
2 stops10h 50m
Tue 11/103:10 pm -
1 stop5h 50m
Deal found 9/16![Southwest logo]()
$289
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:20 pm -
1 stop6h 09m
Wed 11/111:22 pm -
2 stops12h 37m
Deal found 9/14![United Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:15 am -
1 stop6h 25m
Wed 10/288:10 am -
1 stop6h 20m
Deal found 9/16![Delta logo]()
$327
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:24 am -
2 stops10h 14m
Mon 11/24:17 pm -
1 stop7h 40m
Deal found 9/14![American Airlines logo]()
$425
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:34 am -
2 stops10h 55m
Wed 11/111:46 pm -
2 stops12h 13m
Deal found 9/16![United Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:15 am -
1 stop6h 25m
Wed 10/288:10 am -
1 stop6h 20m
Deal found 9/16![Delta logo]()
$327
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1812:30 am -
1 stop11h 05m
Sat 10/316:40 am -
2 stops9h 15m
Deal found 9/16![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:30 am -
2 stops7h 54m
Mon 11/1611:35 am -
2 stops11h 14m
Deal found 9/16![United Airlines logo]()
$360
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1112:59 am -
1 stop6h 02m
Wed 11/46:00 am -
1 stop5h 36m
Deal found 9/13![Delta logo]()
$334
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:20 am -
2 stops8h 50m
Sat 12/511:15 am -
1 stop9h 00m
Deal found 9/14![Southwest logo]()
$338
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:35 am -
1 stop6h 44m
Tue 11/174:15 pm -
1 stop7h 48m
Deal found 9/14![United Airlines logo]()
$365
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:10 am -
2 stops7h 50m
Fri 11/66:45 am -
2 stops8h 30m
Deal found 9/11![Southwest logo]()
$344
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:30 am -
2 stops8h 14m
Wed 12/24:17 pm -
2 stops9h 31m
Deal found 9/13![American Airlines logo]()
$516
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:15 am -
1 stop6h 25m
Mon 10/55:50 pm -
1 stop6h 35m
Deal found 9/12![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:00 am -
Nonstop3h 03m
Sun 11/154:29 pm -
Nonstop3h 35m
Deal found 9/12![United Airlines logo]()
$374
Last-minute flights from Colorado to South CarolinaDiscover last-minute flight deals from Colorado to South Carolina. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Colorado to South Carolina. Data last updated September 17, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:39 pm -
Nonstop3h 20m
Sun 10/47:54 pm -
Nonstop3h 49m
Deal found 9/12![Frontier logo]()
$242
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:59 pm -
1 stop7h 43m
Wed 10/75:00 pm -
1 stop8h 54m
Deal found 9/14![United Airlines logo]()
$242
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:55 am -
1 stop4h 45m
Wed 10/217:20 pm -
1 stop5h 10m
Deal found 9/13![Southwest logo]()
$248
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:55 am -
1 stop5h 35m
Wed 10/72:10 pm -
1 stop10h 30m
Deal found 9/16![Southwest logo]()
$252
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:19 pm -
1 stop11h 46m
Fri 10/164:47 pm -
Nonstop4h 05m
Deal found 9/14![Frontier logo]()
$251
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:19 pm -
1 stop11h 46m
Wed 10/214:47 pm -
Nonstop4h 05m
Deal found 9/14![Frontier logo]()
$249
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:40 am -
Nonstop3h 22m
Mon 10/269:40 pm -
1 stop12h 49m
Deal found 9/14![Frontier logo]()
$244
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:59 pm -
1 stop7h 43m
Sat 10/2410:38 am -
1 stop6h 59m
Deal found 9/16![United Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:40 am -
1 stop7h 40m
Tue 10/273:55 pm -
1 stop7h 40m
Deal found 9/14![Southwest logo]()
$248
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:19 pm -
1 stop11h 46m
Tue 10/2712:05 pm -
1 stop11h 37m
Deal found 9/16![Frontier logo]()
$247
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:45 am -
1 stop5h 20m
Tue 10/277:10 pm -
1 stop5h 20m
Deal found 9/15![Southwest logo]()
$248
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:43 am -
Nonstop3h 13m
Tue 11/312:05 pm -
1 stop11h 37m
Deal found 9/16![Frontier logo]()
$250
One-way flights from Colorado to South CarolinaSearch for one-way flight options from Colorado to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Colorado to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/98:00 am -
1 stop6h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Delta logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:43 am -
2 stops20h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:19 pm -
1 stop13h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$122
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/68:00 am -
2 stops13h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Delta logo]()
$123
This Super.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:20 pm -
1 stop11h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$123
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:30 am -
1 stop8h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$124
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1312:58 am -
1 stop7h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$124
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:15 am -
1 stop7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$124
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:45 am -
1 stop5h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$124
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:19 pm -
1 stop11h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:31 pm -
2 stops36h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$127
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:02 pm -
1 stop11h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$127
Find flight deals from Colorado to South Carolina
Keep the following information in mind while searching for Colorado to South Carolina flight deals. Data was last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $240 (Priceline) |
One-way from | $118 (Delta) |
Popular in | January |
Cheapest in | April |
Average price | $486 |
Good round-trip deal | $355 or less |
Good one-way deal | $203 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Colorado to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Colorado to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Mon 12/14
12:57 am-10:07 am
1 stop7h 10m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$124
DenverSavannah
DEN Denver Intl - SAV Savannah/Hilton Head
DENSAV
Denver Intl
Wed 12/16
7:05 am-4:50 pm
1 stop7h 45m
Savannah/Hilton Head
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$124
DenverSavannah
DEN Denver Intl - SAV Savannah/Hilton Head
DENSAV
Denver Intl
Tue 12/15
6:00 am-12:55 pm
1 stop4h 55m
Savannah/Hilton Head
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$124
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Sat 11/14
6:35 am-7:35 pm
2 stops11h 00m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$129
DenverCharlotte
DEN Denver Intl - CLT Charlotte Douglas
DENCLT
Denver Intl
Sat 10/24
6:30 am-6:45 pm
2 stops10h 15m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$129
DenverCharlotte
DEN Denver Intl - CLT Charlotte Douglas
DENCLT
Denver Intl
Tue 10/27
8:45 am-6:30 pm
2 stops7h 45m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$129
DenverCharlotte
DEN Denver Intl - CLT Charlotte Douglas
DENCLT
Denver Intl
Wed 12/16
10:55 am-9:00 pm
2 stops8h 05m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$129
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Tue 10/13
11:59 pm-9:14 am
1 stop7h 15m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$132
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Fri 10/16
12:59 am-9:25 am
1 stop6h 26m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$138
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Thu 10/15
12:59 am-10:07 am
1 stop7h 08m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$139
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Colorado to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Colorado with our price prediction graph.
DEN-MYR
DEN-CLT
DEN-GSP
DEN-SAV
COS-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Colorado to South Carolina
USCO-USSC
DEN-MYR
DEN-CLT
DEN-GSP
DEN-SAV
What is the cheapest month to book a flight from Colorado to South Carolina?
Currently, February is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $403). Flying from Colorado to South Carolina in June is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CO to SC?
Find hourly flight availability from Colorado to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2026.
It’s optimal to fly from Colorado to South Carolina at noon. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight in the evening.
Weekly flight availability from Colorado to South Carolina
Explore weekly flight availability from Colorado to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 17, 2026.
The most flights from USCO to USSC are scheduled on a Monday (2 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Colorado to South Carolina?
Airfare is below average for this route at the moment.
Colorado to South Carolina flights typically cost between $314 and $532 in October.The cheapest round-trip price found within the last 5 days was $306 on Southwest (Oct 28-Nov 2).
How far ahead should I book a flight from Colorado to South Carolina?
To ensure you get the cheapest price possible for a flight from Colorado to South Carolina, you should look to book at least 80 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 17, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Colorado to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
8.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
8.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
8.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
8.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
8.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
8.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Colorado to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Colorado to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Colorado to South Carolina by cabin class
Find flights from Colorado to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Colorado and South Carolina flights
Browse other Colorado and South Carolina flight options. Last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Colorado after your stay in South Carolina
Colorado to South Carolina flights
Consider these flights traveling from Colorado to South Carolina.
Top 6 airlines flying from Colorado to South Carolina
Discover the top 6 airlines that operate flights from Colorado to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$155 | Average$260 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$208 | Average$318 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$211 | Average$443 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$244 | Average$398 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$254 | Average$475 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$288 | Average$485 | FlexibilityNo cancel fee | On-time63% |