$69+ Cheap flights from Colorado to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Nov 2 — Nov 91
Round-trip
1 adult, Economy
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Find cheap flights from Colorado to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Colorado to South Carolina
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Cheapest flights from Colorado to South CarolinaExplore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 3, 2026.
Explore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:40 am -
1 stop11h 19m
Mon 11/28:32 pm -
2 stops27h 10m
Deal found 9/30![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:56 pm -
1 stop18h 33m
Fri 10/309:41 am -
2 stops24h 41m
Deal found 9/30![Multiple Airlines logo]()
$265
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:35 am -
Nonstop3h 27m
Wed 10/2811:27 am -
1 stop10h 33m
Deal found 10/1![United Airlines logo]()
$267
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:07 pm -
1 stop5h 40m
Tue 10/276:15 am -
1 stop8h 15m
Deal found 9/30![American Airlines logo]()
$277
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:05 pm -
1 stop12h 50m
Mon 11/98:55 pm -
1 stop5h 30m
Deal found 9/29![Southwest logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:40 am -
1 stop11h 19m
Mon 11/98:32 pm -
2 stops21h 21m
Deal found 9/30![Multiple Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:30 am -
2 stops9h 45m
Wed 10/281:35 pm -
2 stops10h 00m
Deal found 10/1![Southwest logo]()
$287
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:50 am -
1 stop9h 30m
Wed 11/113:25 pm -
2 stops9h 15m
Deal found 10/2![Southwest logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:56 pm -
1 stop14h 48m
Tue 10/274:08 pm -
2 stops31h 34m
Deal found 9/30![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:40 am -
1 stop7h 12m
Thu 11/510:12 am -
1 stop14h 04m
Deal found 10/1![Multiple Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:07 pm -
2 stops14h 07m
Fri 12/46:12 pm -
1 stop16h 01m
Deal found 10/1![Multiple Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:36 am -
2 stops23h 52m
Fri 12/46:12 pm -
1 stop16h 01m
Deal found 10/1![Multiple Airlines logo]()
$305
Best flights from Colorado to South CarolinaDiscover carefully curated flight deals from Colorado to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 3, 2026.
Discover carefully curated flight deals from Colorado to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 3, 2026.
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:59 pm -
1 stop8h 22m
Wed 11/1111:27 am -
1 stop8h 30m
Deal found 10/2![United Airlines logo]()
$277
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:30 pm -
2 stops7h 35m
Mon 11/98:55 pm -
1 stop5h 30m
Deal found 9/29![Southwest logo]()
$282
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am -
1 stop7h 08m
Sat 11/78:03 am -
1 stop7h 09m
Deal found 9/29![Delta logo]()
$355
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:26 pm -
1 stop7h 18m
Tue 11/35:10 pm -
1 stop7h 36m
Deal found 10/1![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:45 am -
Nonstop3h 21m
Wed 11/44:15 pm -
Nonstop3h 59m
Deal found 9/28![United Airlines logo]()
$327
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:30 am -
2 stops9h 20m
Thu 11/58:55 pm -
1 stop5h 30m
Deal found 10/2![Southwest logo]()
$353
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:15 am -
1 stop6h 26m
Thu 12/106:02 pm -
1 stop6h 09m
Deal found 9/28![Delta logo]()
$355
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/241:26 pm -
1 stop7h 00m
Tue 10/278:10 am -
2 stops12h 31m
Deal found 9/29![American Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop5h 15m
Thu 11/51:59 pm -
1 stop8h 17m
Deal found 10/3![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:00 am -
Nonstop3h 02m
Mon 11/94:29 pm -
Nonstop3h 35m
Deal found 10/3![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:55 am -
2 stops9h 15m
Thu 11/121:00 pm -
2 stops10h 50m
Deal found 9/29![Southwest logo]()
$379
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop7h 40m
Sat 11/148:00 am -
1 stop6h 26m
Deal found 10/1![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:00 am -
Nonstop3h 03m
Sun 11/16:20 am -
1 stop6h 06m
Deal found 9/30![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:10 am -
2 stops9h 40m
Wed 10/287:00 am -
2 stops9h 45m
Deal found 9/30![Southwest logo]()
$379
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am -
1 stop7h 40m
Wed 11/183:47 pm -
1 stop7h 03m
Deal found 9/30![Delta logo]()
$359
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:54 pm -
1 stop7h 32m
Thu 11/127:00 am -
1 stop7h 04m
Deal found 10/1![American Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
1 stop6h 03m
Mon 11/25:12 pm -
1 stop6h 33m
Deal found 9/28![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2612:59 am -
1 stop7h 44m
Mon 11/96:05 pm -
1 stop7h 10m
Deal found 10/1![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:10 am -
2 stops8h 15m
Thu 12/103:25 pm -
2 stops9h 10m
Deal found 10/2![Southwest logo]()
$409
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:26 pm -
1 stop7h 18m
Fri 10/305:18 pm -
1 stop8h 13m
Deal found 9/29![American Airlines logo]()
$459
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1512:10 pm -
1 stop7h 49m
Wed 12/165:34 pm -
1 stop6h 25m
Deal found 9/28![United Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am -
1 stop5h 14m
Thu 11/126:05 pm -
1 stop6h 02m
Deal found 9/29![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:55 am -
1 stop5h 35m
Wed 10/2810:25 am -
2 stops8h 00m
Deal found 10/2![Southwest logo]()
$417
This Delta deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:07 pm -
2 stops13h 23m
Tue 10/271:59 pm -
1 stop8h 17m
Deal found 10/3![Delta logo]()
$364
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:30 am -
2 stops10h 05m
Wed 10/212:10 pm -
2 stops10h 05m
Deal found 9/28![Southwest logo]()
$417
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:45 am -
Nonstop3h 21m
Wed 10/284:15 pm -
Nonstop3h 59m
Deal found 9/29![United Airlines logo]()
$437
This Delta deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/241:26 pm -
1 stop4h 44m
Tue 11/35:40 am -
2 stops13h 47m
Deal found 10/3![Delta logo]()
$364
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:10 am -
2 stops10h 10m
Mon 11/163:25 pm -
2 stops9h 15m
Deal found 10/2![Southwest logo]()
$419
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1312:54 pm -
1 stop7h 32m
Mon 11/163:29 pm -
1 stop6h 48m
Deal found 9/29![American Airlines logo]()
$569
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:31 pm -
1 stop7h 20m
Wed 10/287:00 am -
1 stop7h 30m
Deal found 9/30![Delta logo]()
$369
Last-minute flights from Colorado to South CarolinaDiscover last-minute flight deals from Colorado to South Carolina. Data last updated October 3, 2026 and is based on user searches.
Discover last-minute flight deals from Colorado to South Carolina. Data last updated October 3, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:07 pm -
1 stop5h 40m
Tue 10/276:15 am -
1 stop8h 15m
Deal found 9/30![American Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:56 pm -
1 stop14h 48m
Tue 10/274:08 pm -
2 stops31h 34m
Deal found 9/30![Multiple Airlines logo]()
$293
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:35 am -
Nonstop3h 27m
Wed 10/2811:27 am -
1 stop10h 33m
Deal found 10/1![United Airlines logo]()
$267
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:30 am -
2 stops9h 45m
Wed 10/281:35 pm -
2 stops10h 00m
Deal found 10/1![Southwest logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:56 pm -
1 stop18h 33m
Fri 10/309:41 am -
2 stops24h 41m
Deal found 9/30![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:40 am -
1 stop11h 19m
Mon 11/28:32 pm -
2 stops27h 10m
Deal found 9/30![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:40 am -
1 stop7h 12m
Thu 11/510:12 am -
1 stop14h 04m
Deal found 10/1![Multiple Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:40 am -
1 stop11h 19m
Mon 11/98:32 pm -
2 stops21h 21m
Deal found 9/30![Multiple Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:30 pm -
2 stops7h 35m
Mon 11/98:55 pm -
1 stop5h 30m
Deal found 9/29![Southwest logo]()
$282
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:50 am -
1 stop9h 30m
Wed 11/113:25 pm -
2 stops9h 15m
Deal found 10/2![Southwest logo]()
$288
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:17 pm -
1 stop5h 47m
Mon 11/166:12 am -
1 stop5h 54m
Deal found 9/30![American Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:30 am -
2 stops23h 33m
Mon 11/166:12 pm -
1 stop16h 12m
Deal found 9/30![Multiple Airlines logo]()
$312
One-way flights from Colorado to South CarolinaSearch for one-way flight options from Colorado to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 3, 2026.
Search for one-way flight options from Colorado to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:41 am -
2 stops21h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Frontier logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:18 pm -
2 stops17h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:30 am -
2 stops49h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Frontier logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:41 am -
2 stops20h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:00 am -
3 stops22h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:18 pm -
2 stops18h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:05 am -
1 stop28h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:22 pm -
2 stops46h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:12 pm -
2 stops14h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:07 pm -
2 stops14h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:05 am -
1 stop28h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:38 am -
2 stops26h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$124
Find flight deals from Colorado to South Carolina
Keep the following information in mind while searching for Colorado to South Carolina flight deals. Data was last updated October 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $248 (Kiwi.com) |
One-way from | $69 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $474 |
Good round-trip deal | $418 or less |
Good one-way deal | $203 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Colorado to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 3, 2026.
Use the filters below to find and compare flights from Colorado to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Sun 10/25
11:59 pm-10:21 am
1 stop8h 22m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$139
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Sun 10/25
12:59 am-10:07 am
1 stop7h 08m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$139
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Wed 10/21
6:00 am-3:16 pm
1 stop7h 16m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$139
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Sat 10/31
6:57 pm-3:33 pm
2 stops18h 36m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$142
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Wed 10/28
8:35 am-8:10 pm
2 stops9h 35m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$144
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Tue 10/27
8:10 am-7:30 pm
2 stops9h 20m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$144
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Tue 10/27
9:45 am-3:06 pm
Nonstop3h 21m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$164
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Sat 10/31
6:00 am-3:01 pm
1 stop7h 01m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$170
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Fri 10/30
6:00 am-1:30 pm
1 stop5h 30m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$170
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Sat 10/31
6:00 am-1:18 pm
1 stop5h 18m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$174
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Colorado to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Colorado with our price prediction graph.
DEN-MYR
DEN-GSP
DEN-CHS
COS-CAE
COS-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Colorado to South Carolina
USCO-USSC
DEN-MYR
DEN-GSP
DEN-CHS
COS-CAE
What is the cheapest month to book a flight from Colorado to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $399). Flying from Colorado to South Carolina in June is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CO to SC?
Find hourly flight availability from Colorado to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 3, 2026.
It’s optimal to fly from Colorado to South Carolina at noon. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight in the evening.
How much does it cost to fly round-trip from Colorado to South Carolina?
Airfare is below average for this route at the moment.
Colorado to South Carolina flights typically cost between $367 and $616 in October.The cheapest round-trip price found within the last 5 days was $316 on Multiple Airlines (Oct 23-Oct 26).
How far ahead should I book a flight from Colorado to South Carolina?
To ensure you get the cheapest price possible for a flight from Colorado to South Carolina, you should look to book at least 72 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 3, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Colorado to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Colorado to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Colorado to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Colorado to South Carolina by cabin class
Find flights from Colorado to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Colorado and South Carolina flights
Browse other Colorado and South Carolina flight options. Last updated on October 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Colorado after your stay in South Carolina
Colorado to South Carolina flights
Consider these flights traveling from Colorado to South Carolina.
Top 6 airlines flying from Colorado to South Carolina
Discover the top 6 airlines that operate flights from Colorado to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$155 | Average$260 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$203 | Average$483 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$208 | Average$318 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$244 | Average$394 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$254 | Average$477 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$288 | Average$467 | FlexibilityNo cancel fee | On-time63% |