$110+ Cheap flights from Colorado to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Colorado to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Colorado to South Carolina
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Cheapest flights from Colorado to South CarolinaExplore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:08 am -
1 stop22h 24m
Mon 12/148:52 pm -
2 stops27h 03m
Deal found 10/29![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:08 pm -
1 stop24h 04m
Mon 12/148:32 pm -
1 stop15h 17m
Deal found 10/27![Multiple Airlines logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:08 am -
1 stop28h 21m
Mon 12/148:52 pm -
2 stops27h 03m
Deal found 10/29![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:20 pm -
1 stop28h 32m
Mon 12/78:52 pm -
1 stop13h 21m
Deal found 10/29![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:08 am -
1 stop24h 36m
Mon 12/146:12 pm -
2 stops29h 43m
Deal found 10/29![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:08 am -
1 stop22h 24m
Tue 12/1511:28 am -
1 stop22h 45m
Deal found 10/29![Multiple Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/119:08 am -
1 stop9h 04m
Mon 12/148:32 pm -
1 stop15h 17m
Deal found 10/27![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:08 am -
1 stop9h 04m
Sun 12/1310:12 am -
1 stop24h 01m
Deal found 10/29![Multiple Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:08 am -
1 stop9h 04m
Tue 12/1511:28 am -
1 stop22h 45m
Deal found 10/29![Multiple Airlines logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:51 am -
1 stop19h 12m
Tue 12/14:03 pm -
2 stops25h 42m
Deal found 10/28![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:08 pm -
1 stop15h 36m
Mon 12/71:53 pm -
2 stops34h 02m
Deal found 10/26![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:16 am -
2 stops42h 47m
Thu 12/102:46 pm -
1 stop8h 44m
Deal found 10/28![Multiple Airlines logo]()
$306
Best flights from Colorado to South CarolinaDiscover carefully curated flight deals from Colorado to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Colorado to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:45 am -
2 stops8h 33m
Mon 12/75:00 pm -
1 stop6h 59m
Deal found 10/28![United Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:31 pm -
1 stop5h 08m
Mon 12/73:46 pm -
1 stop8h 25m
Deal found 10/26![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:30 am -
1 stop10h 35m
Sun 12/135:30 am -
1 stop8h 05m
Deal found 10/25![Southwest logo]()
$377
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:59 pm -
2 stops7h 53m
Mon 12/77:20 am -
1 stop6h 49m
Deal found 10/28![American Airlines logo]()
$436
This Alaska Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/62:51 pm -
2 stops24h 26m
Sat 12/126:20 pm -
2 stops29h 19m
Deal found 10/28![Alaska Airlines logo]()
$605
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:10 am -
Nonstop3h 02m
Tue 12/155:00 pm -
1 stop7h 24m
Deal found 10/29![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:07 pm -
1 stop4h 44m
Mon 12/145:35 am -
1 stop8h 31m
Deal found 10/26![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:59 pm -
1 stop8h 03m
Sun 11/224:29 pm -
Nonstop3h 35m
Deal found 10/27![United Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/1310:15 am -
2 stops6h 55m
Thu 1/144:00 pm -
1 stop6h 45m
Deal found 10/25![Southwest logo]()
$390
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:10 am -
1 stop7h 48m
Thu 12/37:50 pm -
1 stop5h 32m
Deal found 10/29![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2512:55 pm -
1 stop6h 10m
Mon 3/16:50 pm -
1 stop6h 29m
Deal found 10/27![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/45:25 am -
2 stops11h 05m
Thu 1/144:00 pm -
1 stop6h 45m
Deal found 10/25![Southwest logo]()
$396
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:00 am -
1 stop8h 17m
Sat 12/124:18 pm -
Nonstop3h 37m
Deal found 10/25![United Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:33 am -
2 stops9h 14m
Wed 11/1810:14 am -
1 stop6h 37m
Deal found 10/30![American Airlines logo]()
$476
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:30 am -
2 stops6h 30m
Sat 12/127:05 am -
1 stop5h 30m
Deal found 10/25![Southwest logo]()
$404
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/256:05 am -
1 stop6h 44m
Thu 4/810:14 am -
1 stop6h 02m
Deal found 10/28![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/158:30 am -
1 stop11h 10m
Fri 12/184:45 pm -
1 stop7h 35m
Deal found 10/28![Southwest logo]()
$418
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/121:18 pm -
2 stops8h 41m
Tue 2/166:15 am -
2 stops11h 36m
Deal found 10/25![American Airlines logo]()
$511
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/144:40 pm -
1 stop4h 55m
Sun 4/186:45 pm -
1 stop7h 38m
Deal found 10/25![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:45 am -
2 stops9h 08m
Sun 12/64:18 pm -
1 stop5h 52m
Deal found 10/27![United Airlines logo]()
$463
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:55 am -
2 stops7h 55m
Sat 11/216:20 am -
2 stops6h 35m
Deal found 10/28![Southwest logo]()
$424
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/179:07 am -
1 stop5h 23m
Fri 11/205:10 pm -
1 stop8h 49m
Deal found 10/28![American Airlines logo]()
$528
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1412:59 am -
1 stop7h 09m
Fri 4/236:00 am -
1 stop5h 35m
Deal found 10/27![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2410:00 am -
Nonstop3h 02m
Wed 12/26:30 am -
1 stop6h 57m
Deal found 10/29![United Airlines logo]()
$464
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:10 pm -
2 stops8h 05m
Wed 12/211:00 am -
2 stops7h 00m
Deal found 10/26![Southwest logo]()
$425
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:40 pm -
1 stop7h 07m
Mon 12/76:00 am -
1 stop8h 33m
Deal found 10/26![Delta logo]()
$419
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:45 am -
1 stop6h 09m
Wed 12/96:15 am -
2 stops13h 04m
Deal found 10/27![United Airlines logo]()
$474
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1210:40 am -
2 stops9h 05m
Sun 2/147:15 am -
2 stops8h 05m
Deal found 10/28![Southwest logo]()
$434
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2612:59 am -
1 stop7h 54m
Fri 4/26:00 am -
1 stop5h 35m
Deal found 10/29![Delta logo]()
$419
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/59:41 am -
Nonstop3h 19m
Fri 1/84:02 pm -
Nonstop4h 08m
Deal found 10/29![United Airlines logo]()
$491
Last-minute flights from Colorado to South CarolinaDiscover last-minute flight deals from Colorado to South Carolina. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Colorado to South Carolina. Data last updated October 30, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:40 am -
1 stop7h 12m
Tue 11/1711:28 am -
1 stop22h 56m
Deal found 10/28![Multiple Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:40 am -
1 stop7h 12m
Thu 11/1910:12 am -
1 stop7h 23m
Deal found 10/25![Multiple Airlines logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:58 pm -
1 stop23h 09m
Sat 11/218:47 pm -
1 stop13h 52m
Deal found 10/28![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:10 pm -
1 stop11h 40m
Sun 11/228:15 pm -
1 stop25h 51m
Deal found 10/27![Multiple Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:58 pm -
1 stop12h 34m
Wed 11/255:05 pm -
2 stops31h 06m
Deal found 10/27![Multiple Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:40 am -
1 stop11h 19m
Mon 11/232:33 pm -
1 stop21h 40m
Deal found 10/27![Multiple Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:51 am -
1 stop21h 04m
Tue 11/242:46 pm -
1 stop9h 56m
Deal found 10/27![Multiple Airlines logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:51 am -
1 stop19h 12m
Tue 12/14:03 pm -
2 stops25h 42m
Deal found 10/28![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:51 am -
1 stop19h 12m
Wed 12/25:58 pm -
1 stop16h 11m
Deal found 10/28![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:51 am -
1 stop19h 22m
Tue 12/111:28 am -
2 stops21h 08m
Deal found 10/27![Multiple Airlines logo]()
$327
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:29 am -
1 stop6h 58m
Tue 12/15:17 pm -
1 stop8h 42m
Deal found 10/27![American Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:45 am -
2 stops8h 25m
Thu 12/32:50 pm -
1 stop9h 00m
Deal found 10/26![Southwest logo]()
$334
One-way flights from Colorado to South CarolinaSearch for one-way flight options from Colorado to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Colorado to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/910:34 am -
2 stops33h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:08 pm -
1 stop16h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:10 pm -
1 stop11h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/87:18 am -
2 stops36h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/77:18 am -
2 stops26h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/294:17 pm -
2 stops37h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:00 am -
2 stops21h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/138:40 pm -
2 stops33h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:25 am -
1 stop26h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/239:23 pm -
2 stops34h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:43 am -
1 stop22h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:40 am -
1 stop11h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$145
Find flight deals from Colorado to South Carolina
Keep the following information in mind while searching for Colorado to South Carolina flight deals. Data was last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $235 (Kiwi.com) |
One-way from | $110 (Kiwi.com) |
Popular in | January |
Cheapest in | April |
Average price | $376 |
Good round-trip deal | $407 or less |
Good one-way deal | $235 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Colorado to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Colorado to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Thu 1/7
7:18 am-11:44 am
2 stops26h 26m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$125
DenverMyrtle Beach
DEN Denver Intl - MYR Myrtle Beach Intl
DENMYR
Denver Intl
Wed 11/18
7:10 pm-8:50 am
1 stop11h 40m
Myrtle Beach Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$154
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Wed 12/16
6:30 am-5:25 pm
2 stops8h 55m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$156
Colorado SpringsGreenville
COS Colorado Springs - GSP Greenville
COSGSP
Colorado Springs
Tue 12/1
1:40 pm-10:22 pm
1 stop6h 42m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$160
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Fri 11/20
11:59 pm-9:13 am
1 stop7h 14m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$171
DenverCharleston
DEN Denver Intl - CHS Charleston
DENCHS
Denver Intl
Fri 1/1
6:00 am-2:46 pm
1 stop6h 46m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$182
Colorado SpringsCharleston
COS Colorado Springs - CHS Charleston
COSCHS
Colorado Springs
Wed 11/18
6:00 am-3:06 pm
1 stop7h 06m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$193
Colorado SpringsCharleston
COS Colorado Springs - CHS Charleston
COSCHS
Colorado Springs
Mon 11/23
6:00 am-12:52 pm
1 stop4h 52m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$193
DenverGreenville
DEN Denver Intl - GSP Greenville
DENGSP
Denver Intl
Fri 12/25
10:55 am-8:50 pm
2 stops7h 55m
Greenville
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$195
Colorado SpringsCharleston
COS Colorado Springs - CHS Charleston
COSCHS
Colorado Springs
Wed 11/18
6:55 am-5:25 pm
2 stops8h 30m
Charleston
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$198
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Colorado to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Colorado with our price prediction graph.
DEN-CHS
DEN-MYR
DEN-GSP
COS-CHS
DEN-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Colorado to South Carolina
USCO-USSC
DEN-CHS
DEN-MYR
DEN-GSP
COS-CHS
What is the cheapest month to book a flight from Colorado to South Carolina?
Currently, February is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $405). Flying from Colorado to South Carolina in June is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CO to SC?
Find hourly flight availability from Colorado to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2026.
It’s optimal to fly from Colorado to South Carolina at noon. By choosing this option you can save up to 5% on the cost of your flight, compared to a flight in the morning.
How much does it cost to fly round-trip from Colorado to South Carolina?
Airfare is below average for this route at the moment.
Colorado to South Carolina flights typically cost between $355 and $532 in December.The cheapest round-trip price found within the last 5 days was $342 on Southwest (Dec 11-Dec 12).
How far ahead should I book a flight from Colorado to South Carolina?
To ensure you get the cheapest price possible for a flight from Colorado to South Carolina, you should look to book at least 72 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 30, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Colorado to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.9
Comfort
8.0
Entertainment
7.4
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
7.9
Comfort
8.0
Entertainment
7.4
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
7.9
Comfort
8.0
Entertainment
7.4
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
7.9
Comfort
8.0
Entertainment
7.4
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
7.9
Comfort
8.0
Entertainment
7.4
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
7.9
Comfort
8.0
Entertainment
7.4
Food
7.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Colorado to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Colorado to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Colorado to South Carolina by cabin class
Find flights from Colorado to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Colorado and South Carolina flights
Browse other Colorado and South Carolina flight options. Last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Colorado after your stay in South Carolina
Colorado to South Carolina flights
Consider these flights traveling from Colorado to South Carolina.
Top 6 airlines flying from Colorado to South Carolina
Discover the top 6 airlines that operate flights from Colorado to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$155 | Average$260 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$203 | Average$472 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$208 | Average$318 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$229 | Average$414 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$464 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$288 | Average$469 | FlexibilityNo cancel fee | On-time63% |