$120+ Cheap flights from Colorado to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — CHS
Jul 19 — Jul 261
Round-trip
1 adult, Economy
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Find cheap flights from Colorado to South Carolina with Cheapflights
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Cheapest flights from Colorado to South CarolinaExplore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 19, 2026.
Explore the most affordable flight options available from Colorado to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1511:59 pm
DEN
- GSP
1 stop17h 45m
Multiple Airlines
Mon 9/217:10 pm
GSP
- DEN
1 stop20h 31m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:39 pm
DEN
- SAV
1 stop20h 19m
Multiple Airlines
Mon 8/174:20 pm
SAV
- DEN
1 stop9h 33m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$275
This Frontier deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/43:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Sun 7/198:02 pm
CLT
- DEN
1 stop13h 31m
Frontier
Deal found 6/15![Frontier logo]()
$285
This Frontier deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/223:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Wed 7/110:14 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 6/15![Frontier logo]()
$286
This Frontier deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/203:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Thu 7/27:14 pm
CLT
- DEN
Nonstop3h 54m
Frontier
Deal found 6/15![Frontier logo]()
$287
This Cheapflightsfares deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/63:52 pm
DEN
- CLT
Nonstop3h 27m
Frontier
Mon 7/1310:04 pm
CLT
- DEN
Nonstop3h 44m
Frontier
Deal found 6/14![Frontier logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/173:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Wed 6/2410:14 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 6/15![Frontier logo]()
$290
This Cheapflightsfares deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/203:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Sat 6/2710:14 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 6/15![Frontier logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:55 pm
DEN
- MYR
2 stops13h 10m
Multiple Airlines
Sun 8/303:53 pm
MYR
- DEN
1 stop9h 48m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$292
This Frontier deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/193:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Wed 7/110:14 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 6/15![Frontier logo]()
$292
This Frontier deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/203:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Wed 6/2410:14 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 6/15![Frontier logo]()
$294
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/33:11 pm
DEN
- CAE
1 stop6h 23m
American Airlines
Sat 7/114:10 pm
CAE
- DEN
1 stop8h 51m
American Airlines
Deal found 6/18![American Airlines logo]()
$295
Best flights from Colorado to South CarolinaDiscover carefully curated flight deals from Colorado to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 19, 2026.
Discover carefully curated flight deals from Colorado to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 19, 2026.
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
DEN
- HHH
1 stop6h 03m
United Airlines
Fri 8/282:48 pm
HHH
- DEN
1 stop6h 57m
United Airlines
Deal found 6/17![United Airlines logo]()
$305
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:05 am
DEN
- HHH
1 stop6h 14m
Delta
Mon 11/212:00 pm
HHH
- DEN
1 stop8h 04m
Delta
Deal found 6/15![Delta logo]()
$305
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:15 am
DEN
- HHH
1 stop6h 42m
American Airlines
Mon 8/173:27 pm
HHH
- DEN
1 stop8h 47m
American Airlines
Deal found 6/17![American Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:15 am
DEN
- GSP
1 stop8h 50m
Southwest
Wed 8/197:00 am
GSP
- DEN
2 stops9h 45m
Southwest
Deal found 6/18![Southwest logo]()
$334
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:52 pm
DEN
- GSP
1 stop7h 56m
United Airlines
Mon 9/284:25 pm
GSP
- DEN
Nonstop3h 31m
United Airlines
Deal found 6/16![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:05 am
DEN
- CAE
1 stop6h 05m
Delta
Wed 11/45:10 pm
CAE
- DEN
1 stop7h 07m
Delta
Deal found 6/16![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:00 am
DEN
- CLT
1 stop5h 25m
Southwest
Sat 8/156:30 am
CLT
- DEN
2 stops7h 15m
Southwest
Deal found 6/15![Southwest logo]()
$334
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:59 pm
DEN
- SAV
1 stop8h 56m
United Airlines
Tue 9/224:10 pm
SAV
- DEN
Nonstop3h 45m
United Airlines
Deal found 6/17![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:00 pm
DEN
- GSP
1 stop4h 49m
Delta
Fri 11/277:15 am
GSP
- DEN
1 stop8h 48m
Delta
Deal found 6/17![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:00 am
DEN
- CAE
1 stop6h 23m
American Airlines
Sat 7/117:23 pm
CAE
- DEN
1 stop6h 27m
American Airlines
Deal found 6/19![American Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:40 am
DEN
- CLT
1 stop5h 30m
Southwest
Thu 10/1510:35 am
CLT
- DEN
2 stops10h 00m
Southwest
Deal found 6/15![Southwest logo]()
$334
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:19 am
DEN
- GSP
1 stop4h 36m
Delta
Sun 8/168:49 am
GSP
- DEN
1 stop8h 03m
Delta
Deal found 6/14![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
DEN
- HHH
1 stop6h 03m
United Airlines
Thu 8/272:48 pm
HHH
- DEN
1 stop8h 56m
United Airlines
Deal found 6/15![United Airlines logo]()
$346
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:40 pm
DEN
- CLT
Nonstop3h 00m
Southwest
Fri 11/278:55 pm
CLT
- DEN
1 stop5h 25m
Southwest
Deal found 6/18![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:00 am
DEN
- GSP
1 stop4h 41m
Delta
Sun 8/95:46 am
GSP
- DEN
1 stop4h 48m
Delta
Deal found 6/14![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/711:59 pm
DEN
- AGS
1 stop7h 52m
American Airlines
Sat 9/127:06 am
AGS
- DEN
1 stop7h 21m
American Airlines
Deal found 6/18![American Airlines logo]()
$400
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:25 am
DEN
- CHS
2 stops8h 50m
Southwest
Mon 12/147:30 am
CHS
- DEN
2 stops7h 50m
Southwest
Deal found 6/15![Southwest logo]()
$353
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am
DEN
- CAE
1 stop5h 13m
Delta
Mon 9/287:20 pm
CAE
- DEN
1 stop5h 38m
Delta
Deal found 6/18![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:01 am
DEN
- CHS
Nonstop3h 27m
United Airlines
Wed 8/2611:10 am
CHS
- DEN
1 stop7h 43m
United Airlines
Deal found 6/15![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:10 pm
DEN
- CHS
Nonstop3h 10m
Southwest
Mon 10/55:15 pm
CHS
- DEN
Nonstop3h 50m
Southwest
Deal found 6/18![Southwest logo]()
$359
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:40 pm
DEN
- CLT
1 stop5h 13m
Delta
Mon 10/264:30 pm
CLT
- DEN
1 stop7h 47m
Delta
Deal found 6/17![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:00 am
COS
- MYR
1 stop5h 37m
American Airlines
Sat 9/128:08 am
MYR
- COS
2 stops10h 21m
American Airlines
Deal found 6/18![American Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
DEN
- HHH
1 stop6h 03m
United Airlines
Tue 8/182:48 pm
HHH
- DEN
1 stop6h 57m
United Airlines
Deal found 6/16![United Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2012:59 am
DEN
- CLT
1 stop5h 49m
Delta
Mon 9/2811:31 am
CLT
- DEN
1 stop5h 53m
Delta
Deal found 6/14![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:05 am
DEN
- CHS
2 stops8h 05m
Southwest
Wed 7/2910:45 am
CHS
- DEN
2 stops8h 15m
Southwest
Deal found 6/17![Southwest logo]()
$363
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/238:00 am
COS
- MYR
2 stops7h 42m
American Airlines
Sat 9/54:23 pm
MYR
- COS
1 stop8h 30m
American Airlines
Deal found 6/14![American Airlines logo]()
$474
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2312:59 am
DEN
- CLT
1 stop5h 53m
Delta
Mon 7/277:50 pm
CLT
- DEN
1 stop6h 33m
Delta
Deal found 6/15![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:40 am
COS
- CHS
1 stop6h 52m
United Airlines
Wed 8/266:30 am
CHS
- COS
1 stop6h 03m
United Airlines
Deal found 6/18![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:25 am
DEN
- SAV
2 stops9h 50m
Southwest
Mon 7/134:50 pm
SAV
- DEN
1 stop6h 20m
Southwest
Deal found 6/15![Southwest logo]()
$364
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:35 am
DEN
- CLT
1 stop5h 39m
Delta
Sun 9/209:42 am
CLT
- DEN
1 stop6h 09m
Delta
Deal found 6/14![Delta logo]()
$329
Last-minute flights from Colorado to South CarolinaDiscover last-minute flight deals from Colorado to South Carolina. Data last updated June 19, 2026 and is based on user searches.
Discover last-minute flight deals from Colorado to South Carolina. Data last updated June 19, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/193:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Wed 7/110:14 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 6/15![Frontier logo]()
$292
This Frontier deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/203:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Thu 7/27:14 pm
CLT
- DEN
Nonstop3h 54m
Frontier
Deal found 6/15![Frontier logo]()
$287
This Cheapflightsfares deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/203:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Sat 6/2710:14 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 6/15![Frontier logo]()
$291
This Frontier deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/203:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Wed 6/2410:14 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 6/15![Frontier logo]()
$294
This Frontier deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/223:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Wed 7/110:14 pm
CLT
- DEN
Nonstop4h 02m
Frontier
Deal found 6/15![Frontier logo]()
$286
This Cheapflightsfares deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2512:55 pm
DEN
- CLT
Nonstop3h 24m
Frontier
Tue 8/48:02 pm
CLT
- DEN
1 stop14h 05m
Frontier
Deal found 6/14![Frontier logo]()
$297
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/33:11 pm
DEN
- CAE
1 stop6h 23m
American Airlines
Sat 7/114:10 pm
CAE
- DEN
1 stop8h 51m
American Airlines
Deal found 6/18![American Airlines logo]()
$295
This Frontier deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/43:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Sun 7/198:02 pm
CLT
- DEN
1 stop13h 31m
Frontier
Deal found 6/15![Frontier logo]()
$285
This Cheapflightsfares deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/63:52 pm
DEN
- CLT
Nonstop3h 27m
Frontier
Mon 7/1310:04 pm
CLT
- DEN
Nonstop3h 44m
Frontier
Deal found 6/14![Frontier logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:52 pm
DEN
- CLT
Nonstop3h 27m
Frontier
Mon 7/136:41 pm
CLT
- DEN
2 stops27h 22m
Frontier
Deal found 6/18![Frontier logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:30 am
DEN
- CLT
2 stops12h 37m
Frontier
Fri 7/1710:04 pm
CLT
- DEN
Nonstop3h 44m
Frontier
Deal found 6/17![Frontier logo]()
$295
This Cheapflightsfares deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/113:52 pm
DEN
- CLT
Nonstop3h 27m
Frontier
Wed 7/1512:24 pm
CLT
- DEN
1 stop21h 09m
Frontier
Deal found 6/17![Frontier logo]()
$296
One-way flights from Colorado to South CarolinaSearch for one-way flight options from Colorado to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 19, 2026.
Search for one-way flight options from Colorado to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:39 pm
DEN
- SAV
1 stop20h 19m
Allegiant Air
Deal found 6/16![Allegiant Air logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/43:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Deal found 6/18![Frontier logo]()
$122
This Cheapflightsfares deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:59 pm
DEN
- CLT
1 stop7h 12m
Frontier
Deal found 6/18![Frontier logo]()
$123
This Priceline deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
DEN
- MYR
1 stop6h 47m
Frontier
Deal found 6/18![Frontier logo]()
$125
This Frontier deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:09 am
DEN
- CLT
1 stop6h 33m
Frontier
Deal found 6/17![Frontier logo]()
$125
This Super.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/243:56 pm
DEN
- CLT
Nonstop3h 29m
Frontier
Deal found 6/18![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:40 am
DEN
- CHS
1 stop13h 56m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:59 pm
DEN
- CLT
1 stop12h 16m
Frontier
Deal found 6/18![Frontier logo]()
$129
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/41:25 pm
DEN
- CAE
1 stop5h 51m
United Airlines
Deal found 6/18![United Airlines logo]()
$131
This Frontier deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:59 pm
DEN
- CLT
1 stop10h 39m
Frontier
Deal found 6/18![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1411:59 pm
DEN
- CHS
1 stop10h 32m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:59 pm
DEN
- CLT
1 stop12h 16m
Frontier
Deal found 6/18![Frontier logo]()
$132
Find flight deals from Colorado to South Carolina
Keep the following information in mind while searching for Colorado to South Carolina flight deals. Data was last updated June 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $274 (Kiwi.com) |
One-way from | $120 (Kiwi.com) |
Popular in | January |
Cheapest in | October |
Average price | $487 |
Good round-trip deal | $399 or less |
Good one-way deal | $259 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Colorado to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 19, 2026.
Use the filters below to find and compare flights from Colorado to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverHilton Head Island
DEN - HHH
DENHHH
Denver Intl
Sat 8/22
6:00 am-2:03 pm
1 stop6h 03m
Hilton Head Island
Fri 8/28
2:48 pm-7:45 pm
1 stop6h 57m
$305
DenverHilton Head Island
DEN - HHH
DENHHH
Denver Intl
Tue 10/27
7:05 am-3:19 pm
1 stop6h 14m
Hilton Head Island
Mon 11/2
12:00 pm-6:04 pm
1 stop8h 04m
$305
DenverGreenville
DEN - GSP
DENGSP
Denver Intl
Fri 9/25
11:52 pm-9:48 am
1 stop7h 56m
Greenville
Mon 9/28
4:25 pm-5:56 pm
Nonstop3h 31m
$319
DenverSavannah
DEN - SAV
DENSAV
Denver Intl
Sat 9/19
11:59 pm-10:55 am
1 stop8h 56m
Savannah/Hilton Head
Tue 9/22
4:10 pm-5:55 pm
Nonstop3h 45m
$319
DenverColumbia
DEN - CAE
DENCAE
Denver Intl
Wed 10/28
6:05 am-2:10 pm
1 stop6h 05m
Columbia Metropolitan
Wed 11/4
5:10 pm-10:17 pm
1 stop7h 07m
$321
DenverGreenville
DEN - GSP
DENGSP
Denver Intl
Mon 11/23
12:00 pm-6:49 pm
1 stop4h 49m
Greenville
Fri 11/27
7:15 am-2:03 pm
1 stop8h 48m
$329
DenverGreenville
DEN - GSP
DENGSP
Denver Intl
Thu 8/13
7:19 am-1:55 pm
1 stop4h 36m
Greenville
Sun 8/16
8:49 am-2:52 pm
1 stop8h 03m
$329
DenverGreenville
DEN - GSP
DENGSP
Denver Intl
Thu 8/6
6:00 am-12:41 pm
1 stop4h 41m
Greenville
Sun 8/9
5:46 am-8:34 am
1 stop4h 48m
$329
DenverColumbia
DEN - CAE
DENCAE
Denver Intl
Thu 9/24
6:00 am-1:13 pm
1 stop5h 13m
Columbia Metropolitan
Mon 9/28
7:20 pm-10:58 pm
1 stop5h 38m
$329
DenverCharlotte
DEN - CLT
DENCLT
Denver Intl
Fri 10/23
4:40 pm-11:53 pm
1 stop5h 13m
Charlotte Douglas
Mon 10/26
4:30 pm-10:17 pm
1 stop7h 47m
$329
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Colorado to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Colorado with our price prediction graph.
DEN-GSP
DEN-SAV
DEN-CLT
DEN-MYR
DEN-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Colorado to South Carolina
USCO-USSC
DEN-GSP
DEN-SAV
DEN-CLT
DEN-MYR
What is the cheapest month to book a flight from Colorado to South Carolina?
Currently, December is the cheapest month in which you can book a flight from Colorado to South Carolina (average of $78). Flying from Colorado to South Carolina in January is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CO to SC?
Find hourly flight availability from Colorado to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 19, 2026.
It’s optimal to fly from Colorado to South Carolina at noon. By choosing this option you can save up to 22% on the cost of your flight, compared to a flight in the evening.
Weekly flight availability from Colorado to South Carolina
Explore weekly flight availability from Colorado to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 19, 2026.
The most flights from USCO to USSC are scheduled on a Monday (3 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Colorado to South Carolina?
How far ahead should I book a flight from Colorado to South Carolina?
To ensure you get the cheapest price possible for a flight from Colorado to South Carolina, you should look to book at least 70 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 19, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Colorado to South Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Comfort
8.0
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Comfort
8.0
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Comfort
8.0
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Comfort
8.0
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Comfort
8.0
Entertainment
7.5
Overall
7.9
Boarding
8.1
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Colorado to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Colorado to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Colorado to South Carolina by cabin class
Find flights from Colorado to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Colorado and South Carolina flights
Browse other Colorado and South Carolina flight options. Last updated on June 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Colorado after your stay in South Carolina
Colorado to South Carolina flights
Consider these flights traveling from Colorado to South Carolina.
Top 6 airlines flying from Colorado to South Carolina
Discover the top 6 airlines that operate flights from Colorado to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$139 | Average$274 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$185 | Average$311 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$198 | Average$443 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$201 | Average$380 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$211 | Average$422 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$229 | Average$473 | FlexibilityNo cancel fee | On-time63% |