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South America

$196+ Cheap flights from St. Louis (STL) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BOG
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from St. Louis to South America

Keep the following information in mind while searching for St. Louis to South America flight deals. Data was last updated April 30, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$391
(Kiwi.com)

One-way from

$196
(Kiwi.com)

Popular in

June

Cheapest in

April

Average price

$698
Provider with most accurate pricing for Lambert-St Louis-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Sao Paulo (SAO) flights.
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From Lambert-St Louis to South America
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One-way flight from Lambert-St Louis to South America
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from St. Louis to South America

Cheapest flights from St. Louis to South America
Explore the most affordable flight options available from St. Louis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2510:10 amSTL - MDE
1 stop27h 05mSpirit Airlines
Wed 6/42:13 pmMDE - STL
1 stop19h 02mSpirit Airlines
Deal found 4/28$391
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2510:10 amSTL - MDE
2 stops38h 14mMultiple Airlines
Wed 6/49:12 amMDE - STL
2 stops24h 03mMultiple Airlines
Deal found 4/28$418
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/126:00 amSTL - BOG
1 stop13h 20mUnited Airlines
Thu 5/158:30 amBOG - STL
1 stop13h 33mUnited Airlines
Deal found 4/28$475
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/287:05 amSTL - BOG
2 stops12h 53mDelta
Tue 6/31:35 amBOG - STL
2 stops19h 04mDelta
Deal found 4/28$479
This LATAM Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/127:10 pmSTL - BOG
1 stop18h 30mLATAM Airlines
Sun 6/157:00 amBOG - STL
2 stops16h 51mLATAM Airlines
Deal found 4/28$499
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/165:00 amSTL - BOG
1 stop16h 17mAmerican Airlines
Wed 7/232:10 pmBOG - STL
1 stop9h 47mAmerican Airlines
Deal found 4/28$520
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/125:47 pmSTL - BOG
1 stop18h 12mMultiple Airlines
Thu 6/192:00 pmBOG - STL
1 stop20h 33mMultiple Airlines
Deal found 4/28$550
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/108:25 amSTL - MDE
1 stop12h 45mUnited Airlines
Fri 7/1112:15 amMDE - STL
1 stop9h 19mUnited Airlines
Deal found 4/28$600
This Avianca deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/268:15 amSTL - LIM
2 stops16h 20mAvianca
Tue 9/96:45 pmLIM - STL
2 stops15h 17mAvianca
Deal found 4/29$624
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/110:08 amSTL - MDE
2 stops13h 27mAmerican Airlines
Fri 7/412:45 amMDE - STL
2 stops14h 28mAmerican Airlines
Deal found 4/28$653
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/269:00 amSTL - LIM
1 stop12h 10mDelta
Mon 9/158:50 amLIM - STL
2 stops14h 49mDelta
Deal found 4/29$669
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/46:00 amSTL - MDE
2 stops36h 28mDelta
Wed 5/215:31 amMDE - STL
2 stops18h 07mDelta
Deal found 4/28$674

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from St. Louis to South America that are best for you.

Fly from

St. Louis

Fly to

South America

Route

Depart

Return

Price

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sun 5/25

10:10 am-1:15 pm

1 stop27h 05m

Medellín Jose Maria Cordova Intl

Wed 6/4

2:13 pm-9:15 am

1 stop19h 02m

$391

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sun 5/25

10:10 am-12:24 am

2 stops38h 14m

Medellín Jose Maria Cordova Intl

Wed 6/4

9:12 am-9:15 am

2 stops24h 03m

$418

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

Mon 5/12

6:00 am-7:20 pm

1 stop13h 20m

Bogotá El Dorado

Wed 5/14

12:14 am-3:49 pm

1 stop15h 35m

$475

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

Wed 5/28

7:05 am-7:58 pm

2 stops12h 53m

Bogotá El Dorado

Wed 6/4

1:35 am-8:39 pm

2 stops19h 04m

$479

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

Thu 6/12

7:10 pm-4:35 pm

2 stops21h 25m

Bogotá El Dorado

Sun 6/15

7:00 am-11:51 pm

2 stops16h 51m

$499

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

Wed 7/16

5:00 am-9:17 pm

1 stop16h 17m

Bogotá El Dorado

Wed 7/23

2:10 pm-11:57 pm

1 stop9h 47m

$520

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

Thu 6/12

5:47 pm-11:59 am

1 stop18h 12m

Bogotá El Dorado

Thu 6/19

2:00 pm-10:33 am

1 stop20h 33m

$550

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 6/10

8:25 am-9:10 pm

1 stop12h 45m

Medellín Jose Maria Cordova Intl

Fri 7/11

12:15 am-9:34 am

1 stop9h 19m

$600

St. LouisLima

STL - LIM

STLLIM

Lambert-St Louis

Tue 8/26

8:15 am-12:35 am

2 stops16h 20m

Lima J Chavez Intl

Tue 9/9

6:45 pm-10:02 am

2 stops15h 17m

$624

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 7/1

10:08 am-11:35 pm

2 stops13h 27m

Medellín Jose Maria Cordova Intl

Fri 7/4

12:45 am-3:13 pm

2 stops14h 28m

$653

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 47 results
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Best time to book a flight from St. Louis to South America

Have a flexible travel schedule? Discover the best time to fly to South America from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to South America

What is the cheapest month to book a flight from St. Louis to South America?

Currently, May is the cheapest month in which you can book a flight from St. Louis to South America (average of $359). Flying from St. Louis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to SA?

Find hourly flight availability from St. Louis to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

When flying from St. Louis to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 30, 2025.
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,767 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,411 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
GOL
7.3
Good
1,068 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to South America?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to South America from St. Louis.

  • What are the cheapest airlines to fly from St. Louis to South America one-way?

    $231 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Copa Airlines and Delta, with prices starting from $274 and $323, respectively.

  • What are the most popular routes from St. Louis to South America?

    The most popular flight routes from St. Louis to South America are Lambert-St Louis - Lima J Chavez Intl, Lambert-St Louis - Medellín Jose Maria Cordova Intl and Lambert-St Louis - Rio de Janeiro–Galeão Intl.

  • Can I find deals for flights from St. Louis to South America that include hotel bookings?

    Yes. In addition to deals on St. Louis to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to South America.

  • Can I find deals for business class flights from St. Louis to South America?

    Yes. Cheapflights offers flight deals from St. Louis to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to South America?

    Currently, May is the cheapest month in which you can book a flight from St. Louis to South America (average of $359). Flying from St. Louis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from St. Louis to South America

Discover the top 5 airlines that operate flights from St. Louis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$285Average$405FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$399Average$913FlexibilityNo cancel feeOn-time69%
DeltaCheapest$399Average$1,005FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$409Average$888FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$474Average$899FlexibilityNo cancel feeOn-time71%

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