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South America

$185+ Cheap flights from St. Louis (STL) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BOG
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from St. Louis to South America

Keep the following information in mind while searching for St. Louis to South America flight deals. Data was last updated June 12, 2025.

Round-trip from

$453
(Mytrip)

One-way from

$185
(LATAM Airlines)

Popular in

June

Cheapest in

April

Average price

$1,378
From Lambert-St Louis to South America
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One-way flight from Lambert-St Louis to South America
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Highest demand for flights based on searches. 5% potential increase in price ($58 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from St. Louis to South America

Cheapest flights from St. Louis to South America
Explore the most affordable flight options available from St. Louis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/911:24 amSTL - BOG
2 stops25h 41mSpirit Airlines
Wed 7/162:00 pmBOG - STL
1 stop26h 31mSpirit Airlines
Deal found 6/11$453
This CheapOair deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/105:26 pmSTL - MDE
1 stop19h 46mSpirit Airlines
Sat 7/192:10 pmMDE - STL
1 stop26h 21mSpirit Airlines
Deal found 6/11$455
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/911:24 amSTL - BOG
2 stops36h 02mMultiple Airlines
Wed 7/162:00 pmBOG - STL
2 stops19h 52mMultiple Airlines
Deal found 6/11$500
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2510:47 amSTL - MDE
3 stops46h 08mMultiple Airlines
Fri 8/12:10 pmMDE - STL
1 stop24h 29mMultiple Airlines
Deal found 6/10$552
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/911:15 amSTL - BOG
1 stop17h 39mUnited Airlines
Mon 8/1812:14 amBOG - STL
1 stop18h 44mUnited Airlines
Deal found 6/9$574
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/911:15 amSTL - MDE
1 stop9h 55mUnited Airlines
Fri 8/1512:15 amMDE - STL
1 stop9h 19mUnited Airlines
Deal found 6/12$586
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/167:00 amSTL - BOG
1 stop12h 15mDelta
Wed 7/232:55 pmBOG - STL
1 stop18h 46mDelta
Deal found 6/10$588
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/165:30 amSTL - BOG
1 stop17h 00mAmerican Airlines
Tue 7/2212:25 amBOG - STL
1 stop19h 06mAmerican Airlines
Deal found 6/10$602
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:34 amSTL - MDE
1 stop14h 21mAmerican Airlines
Fri 10/175:50 amMDE - STL
1 stop17h 19mAmerican Airlines
Deal found 6/10$611
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/168:20 amSTL - UIO
1 stop15h 05mUnited Airlines
Wed 9/2412:35 amUIO - STL
1 stop18h 22mUnited Airlines
Deal found 6/10$614
This LATAM Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/166:00 amSTL - BOG
1 stop13h 15mLATAM Airlines
Tue 7/221:35 amBOG - STL
2 stops17h 12mLATAM Airlines
Deal found 6/12$618
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/165:40 pmSTL - UIO
2 stops25h 25mDelta
Thu 9/259:11 amUIO - STL
2 stops14h 28mDelta
Deal found 6/10$619

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from St. Louis to South America that are best for you.

Fly from

St. Louis

Fly to

South America

Route

Depart

Return

Price

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

Wed 7/9

11:24 am-1:05 pm

2 stops25h 41m

Bogotá El Dorado

Wed 7/16

2:00 pm-4:31 pm

1 stop26h 31m

$453

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 7/10

5:26 pm-1:12 pm

1 stop19h 46m

Medellín Jose Maria Cordova Intl

Sat 7/19

2:10 pm-4:31 pm

1 stop26h 21m

$455

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

Wed 7/9

11:24 am-11:26 pm

2 stops36h 02m

Bogotá El Dorado

Wed 7/16

2:00 pm-9:52 am

2 stops19h 52m

$500

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Fri 7/25

10:47 am-8:55 am

3 stops46h 08m

Medellín Jose Maria Cordova Intl

Fri 8/1

2:10 pm-2:39 pm

1 stop24h 29m

$552

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

Sat 8/9

11:15 am-4:54 am

1 stop17h 39m

Bogotá El Dorado

Mon 8/18

12:14 am-6:58 pm

1 stop18h 44m

$574

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 8/9

11:15 am-9:10 pm

1 stop9h 55m

Medellín Jose Maria Cordova Intl

Fri 8/15

12:15 am-9:34 am

1 stop9h 19m

$586

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

Wed 7/16

7:00 am-7:15 pm

1 stop12h 15m

Bogotá El Dorado

Wed 7/23

2:55 pm-9:41 am

1 stop18h 46m

$588

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

Wed 7/16

5:30 am-10:30 pm

1 stop17h 00m

Bogotá El Dorado

Tue 7/22

12:25 am-7:31 pm

1 stop19h 06m

$602

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Fri 10/10

5:34 am-7:55 pm

1 stop14h 21m

Medellín Jose Maria Cordova Intl

Fri 10/17

5:50 am-11:09 pm

1 stop17h 19m

$611

St. LouisQuito

STL - UIO

STLUIO

Lambert-St Louis

Tue 9/16

8:20 am-11:25 pm

1 stop15h 05m

Quito Mariscal Sucr

Wed 9/24

12:35 am-6:57 pm

1 stop18h 22m

$614

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 56 results
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Best time to book a flight from St. Louis to South America

Have a flexible travel schedule? Discover the best time to fly to South America from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to South America

What is the cheapest month to book a flight from St. Louis to South America?

Currently, May is the cheapest month in which you can book a flight from St. Louis to South America (average of $359). Flying from St. Louis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to SA?

Find hourly flight availability from St. Louis to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from St. Louis to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,950 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,785 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Turkish Airlines
7.3
Good
3,848 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from St. Louis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to South America?

    Located just 12.7 mi from the city center, Lambert-St Louis (STL) is the airport most travelers will use when flying to South America from St. Louis.

  • What are the cheapest airlines to fly from St. Louis to South America one-way?

    $185 is the cheapest one-way deal found within the past few days, from LATAM Airlines. You may also be able to find cheap deals on Spirit Airlines and Delta, with prices starting from $186 and $323, respectively.

  • What are the most popular routes from St. Louis to South America?

    The most popular flight routes from St. Louis to South America are Lambert-St Louis - Lima J Chavez Intl, Lambert-St Louis - Cusco Velazco Astete and Lambert-St Louis - Buenos Aires Ministro Pistarini.

  • Can I find deals for flights from St. Louis to South America that include hotel bookings?

    Yes. In addition to deals on St. Louis to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to South America.

  • Can I find deals for business class flights from St. Louis to South America?

    Yes. Cheapflights offers flight deals from St. Louis to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to South America?

    Currently, May is the cheapest month in which you can book a flight from St. Louis to South America (average of $359). Flying from St. Louis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for St. Louis to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from St. Louis to South America

Discover the top 6 airlines that operate flights from St. Louis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$289Average$1,003FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$293Average$432FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$399Average$926FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$409Average$881FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$474Average$893FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$758Average$767FlexibilityNo cancel feeOn-time67%

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