$192+ Cheap flights from St. Louis (STL) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/21. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BOG
Apr 11 — Apr 181
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to South America
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Cheapest flights from St. Louis to South AmericaExplore the most affordable flight options available from St. Louis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
Explore the most affordable flight options available from St. Louis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:59 pm
STL
- MDE
1 stop20h 01m
Multiple Airlines
Sun 5/31:55 pm
MDE
- STL
2 stops16h 55m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$498
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:23 pm
STL
- MDE
2 stops16h 37m
Multiple Airlines
Fri 5/11:55 pm
MDE
- STL
1 stop9h 24m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$506
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:23 pm
STL
- MDE
2 stops16h 37m
Multiple Airlines
Wed 4/221:55 pm
MDE
- STL
1 stop9h 24m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$510
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/114:05 pm
STL
- BOG
1 stop13h 50m
Multiple Airlines
Fri 4/1710:50 pm
BOG
- STL
1 stop11h 41m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$513
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:59 pm
STL
- BOG
1 stop18h 56m
Multiple Airlines
Sun 4/192:07 pm
BOG
- STL
2 stops16h 43m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$514
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:59 pm
STL
- BOG
1 stop9h 46m
Multiple Airlines
Thu 4/302:07 pm
BOG
- STL
2 stops40h 43m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$519
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:23 pm
STL
- BOG
2 stops40h 49m
Multiple Airlines
Wed 4/298:40 am
BOG
- STL
1 stop14h 39m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$521
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:55 pm
STL
- MDE
1 stop20h 05m
Multiple Airlines
Sun 5/171:55 pm
MDE
- STL
2 stops16h 55m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$523
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:32 pm
STL
- BOG
1 stop11h 58m
Multiple Airlines
Sat 9/1912:05 am
BOG
- STL
1 stop13h 55m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$526
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:15 pm
STL
- BOG
1 stop9h 15m
Multiple Airlines
Fri 4/2410:50 pm
BOG
- STL
1 stop11h 41m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$527
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:23 pm
STL
- MDE
2 stops40h 37m
Multiple Airlines
Wed 4/291:55 pm
MDE
- STL
1 stop9h 24m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$529
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:59 pm
STL
- BOG
1 stop9h 46m
Multiple Airlines
Fri 5/12:07 pm
BOG
- STL
2 stops16h 43m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$531
Best flights from St. Louis to South AmericaDiscover carefully curated flight deals from St. Louis to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
Discover carefully curated flight deals from St. Louis to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:59 pm
STL
- MDE
1 stop20h 01m
Multiple Airlines
Fri 5/11:55 pm
MDE
- STL
1 stop9h 24m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$514
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
STL
- CTG
1 stop7h 20m
Delta
Tue 4/212:35 pm
CTG
- STL
1 stop9h 01m
Delta
Deal found 3/9![Delta logo]()
$586
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:17 am
STL
- MDE
1 stop7h 34m
American Airlines
Tue 8/111:50 pm
MDE
- STL
1 stop21h 08m
American Airlines
Deal found 3/8![American Airlines logo]()
$592
This LATAM Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:50 pm
STL
- CTG
1 stop18h 30m
LATAM Airlines
Thu 5/72:13 pm
CTG
- STL
1 stop17h 57m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$619
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:55 pm
STL
- MDE
2 stops26h 15m
United Airlines
Sat 6/209:45 am
MDE
- STL
2 stops22h 56m
United Airlines
Deal found 3/7![United Airlines logo]()
$625
This lastminute.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:06 am
STL
- GRU
2 stops41h 34m
GOL
Tue 4/2810:05 pm
GRU
- STL
2 stops38h 11m
GOL
Deal found 3/7![GOL logo]()
$901
This Flysmarter deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:38 pm
STL
- CUZ
3 stops18h 42m
British Airways
Tue 4/284:30 pm
CUZ
- STL
2 stops17h 46m
British Airways
Deal found 3/7![British Airways logo]()
$1,039
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:59 pm
STL
- MDE
1 stop20h 01m
Multiple Airlines
Sun 5/31:55 pm
MDE
- STL
1 stop9h 24m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$533
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:16 pm
STL
- BOG
2 stops15h 39m
Multiple Airlines
Fri 4/174:05 pm
BOG
- STL
1 stop31h 14m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:00 am
STL
- MDE
2 stops13h 15m
American Airlines
Sat 5/236:00 am
MDE
- STL
2 stops15h 37m
American Airlines
Deal found 3/10![American Airlines logo]()
$605
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:00 am
STL
- CTG
1 stop7h 15m
Delta
Tue 4/145:30 am
CTG
- STL
2 stops15h 49m
Delta
Deal found 3/10![Delta logo]()
$609
This Gurufare deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:49 am
STL
- BOG
2 stops16h 36m
LATAM Airlines
Wed 5/272:55 pm
BOG
- STL
1 stop9h 04m
LATAM Airlines
Deal found 3/11![LATAM Airlines logo]()
$620
This Air Canada deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:05 am
STL
- EZE
2 stops29h 25m
Air Canada
Wed 6/34:35 pm
EZE
- STL
3 stops53h 50m
Air Canada
Deal found 3/11![Air Canada logo]()
$1,242
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:45 am
STL
- BOG
2 stops11h 35m
United Airlines
Sat 5/912:14 am
BOG
- STL
2 stops12h 33m
United Airlines
Deal found 3/11![United Airlines logo]()
$635
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:19 pm
STL
- BOG
1 stop10h 26m
Multiple Airlines
Sun 5/102:07 pm
BOG
- STL
2 stops18h 48m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$552
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
STL
- CTG
1 stop7h 15m
Delta
Sat 4/1810:15 am
CTG
- STL
2 stops13h 21m
Delta
Deal found 3/8![Delta logo]()
$609
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:24 am
STL
- CTG
1 stop6h 45m
American Airlines
Tue 4/141:25 pm
CTG
- STL
1 stop20h 51m
American Airlines
Deal found 3/10![American Airlines logo]()
$620
This Gurufare deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/510:49 am
STL
- BOG
2 stops9h 46m
LATAM Airlines
Mon 8/3110:35 am
BOG
- STL
2 stops21h 31m
LATAM Airlines
Deal found 3/10![LATAM Airlines logo]()
$621
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:15 pm
STL
- BOG
2 stops23h 05m
United Airlines
Sun 5/108:30 am
BOG
- STL
2 stops15h 54m
United Airlines
Deal found 3/10![United Airlines logo]()
$637
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:06 am
STL
- BOG
1 stop15h 32m
American Airlines
Wed 5/272:10 pm
BOG
- STL
1 stop8h 48m
American Airlines
Deal found 3/11![American Airlines logo]()
$620
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
STL
- CTG
1 stop6h 58m
Delta
Sat 5/305:30 am
CTG
- STL
2 stops18h 29m
Delta
Deal found 3/8![Delta logo]()
$623
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:59 pm
STL
- MDE
1 stop20h 01m
Multiple Airlines
Wed 4/221:55 pm
MDE
- STL
1 stop9h 24m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$573
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:15 pm
STL
- BOG
2 stops23h 05m
United Airlines
Sat 5/912:14 am
BOG
- STL
2 stops19h 37m
United Airlines
Deal found 3/10![United Airlines logo]()
$637
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:15 am
STL
- CTG
2 stops16h 20m
Delta
Fri 5/294:25 am
CTG
- STL
2 stops13h 31m
Delta
Deal found 3/8![Delta logo]()
$629
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:24 am
STL
- CTG
1 stop6h 45m
American Airlines
Sun 5/171:25 pm
CTG
- STL
1 stop8h 59m
American Airlines
Deal found 3/7![American Airlines logo]()
$630
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/194:59 pm
STL
- BOG
1 stop27h 36m
Multiple Airlines
Sun 5/108:40 am
BOG
- STL
1 stop14h 39m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$577
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:35 am
STL
- BOG
1 stop10h 45m
United Airlines
Tue 7/712:14 am
BOG
- STL
1 stop9h 53m
United Airlines
Deal found 3/8![United Airlines logo]()
$638
This KAYAK deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:41 pm
STL
- UIO
2 stops12h 02m
LATAM Airlines
Wed 5/1312:59 am
UIO
- STL
1 stop8h 45m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$702
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/24:54 pm
STL
- MDE
1 stop19h 58m
Multiple Airlines
Sun 4/510:49 am
MDE
- STL
1 stop21h 02m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$587
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2710:09 am
STL
- MDE
1 stop11h 01m
United Airlines
Thu 4/309:45 am
MDE
- STL
1 stop12h 45m
United Airlines
Deal found 3/8![United Airlines logo]()
$653
Last-minute flights from St. Louis to South AmericaDiscover last-minute flight deals from St. Louis to South America. Data last updated March 12, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to South America. Data last updated March 12, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/114:05 pm
STL
- BOG
1 stop13h 50m
Multiple Airlines
Fri 4/1710:50 pm
BOG
- STL
1 stop11h 41m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$513
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:59 pm
STL
- BOG
1 stop18h 56m
Multiple Airlines
Sun 4/192:07 pm
BOG
- STL
2 stops16h 43m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$514
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:23 pm
STL
- MDE
2 stops16h 37m
Multiple Airlines
Wed 4/221:55 pm
MDE
- STL
1 stop9h 24m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$510
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:15 pm
STL
- BOG
1 stop9h 15m
Multiple Airlines
Fri 4/2410:50 pm
BOG
- STL
1 stop11h 41m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$527
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/194:59 pm
STL
- BOG
1 stop9h 46m
Multiple Airlines
Sun 5/102:07 pm
BOG
- STL
2 stops16h 43m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$536
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:23 pm
STL
- BOG
2 stops40h 49m
Multiple Airlines
Wed 4/298:40 am
BOG
- STL
1 stop14h 39m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$521
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:23 pm
STL
- MDE
2 stops40h 37m
Multiple Airlines
Wed 4/291:55 pm
MDE
- STL
1 stop9h 24m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$529
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:59 pm
STL
- BOG
1 stop9h 46m
Multiple Airlines
Thu 4/302:07 pm
BOG
- STL
2 stops40h 43m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$519
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:23 pm
STL
- MDE
2 stops16h 37m
Multiple Airlines
Fri 5/11:55 pm
MDE
- STL
1 stop9h 24m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$506
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:59 pm
STL
- BOG
1 stop9h 46m
Multiple Airlines
Fri 5/12:07 pm
BOG
- STL
2 stops16h 43m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$531
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:23 pm
STL
- MDE
2 stops16h 37m
Multiple Airlines
Mon 4/271:55 pm
MDE
- STL
1 stop9h 24m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$547
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:59 pm
STL
- MDE
1 stop20h 01m
Multiple Airlines
Sun 5/31:55 pm
MDE
- STL
2 stops16h 55m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$498
One-way flights from St. Louis to South AmericaSearch for one-way flight options from St. Louis to South America. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
Search for one-way flight options from St. Louis to South America. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/214:21 pm
STL
- BOG
1 stop19h 34m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:13 pm
STL
- BOG
2 stops48h 22m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:23 pm
STL
- LIM
3 stops52h 39m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:23 pm
STL
- UIO
3 stops27h 10m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$235
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:09 pm
STL
- BOG
1 stop10h 21m
Avianca
Deal found 3/8![Avianca logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:21 am
STL
- LIM
3 stops37h 41m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:59 pm
STL
- UIO
2 stops30h 34m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:23 pm
STL
- UIO
3 stops28h 11m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:23 pm
STL
- LIM
3 stops50h 22m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$252
This Avianca deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:15 pm
STL
- BOG
1 stop9h 15m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:21 am
STL
- UIO
3 stops30h 19m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:23 pm
STL
- UIO
3 stops41h 46m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$266
Find flight deals from St. Louis to South America
Keep the following information in mind while searching for St. Louis to South America flight deals. Data was last updated March 12, 2026.
Round-trip from | $498 (Kiwi.com) |
|---|---|
One-way from | $192 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $733 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from St. Louis to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Fri 4/24
4:59 pm-1:00 pm
1 stop20h 01m
Medellín Jose Maria Cordova Intl
Fri 5/1
1:55 pm-11:19 pm
1 stop9h 24m
$514
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sun 4/26
4:59 pm-1:00 pm
1 stop20h 01m
Medellín Jose Maria Cordova Intl
Sun 5/3
1:55 pm-11:19 pm
1 stop9h 24m
$533
St. LouisBogotá
STL - BOG
STLBOG
Lambert-St Louis
Sat 4/11
8:16 pm-11:55 am
2 stops15h 39m
Bogotá El Dorado
Fri 4/17
4:05 pm-11:19 pm
1 stop31h 14m
$542
St. LouisBogotá
STL - BOG
STLBOG
Lambert-St Louis
Thu 5/7
4:19 pm-2:45 am
1 stop10h 26m
Bogotá El Dorado
Sun 5/10
2:07 pm-8:55 am
2 stops18h 48m
$552
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Fri 4/17
4:59 pm-1:00 pm
1 stop20h 01m
Medellín Jose Maria Cordova Intl
Wed 4/22
1:55 pm-11:19 pm
1 stop9h 24m
$573
St. LouisBogotá
STL - BOG
STLBOG
Lambert-St Louis
Sun 4/19
4:59 pm-8:35 pm
1 stop27h 36m
Bogotá El Dorado
Sun 5/10
8:40 am-11:19 pm
1 stop14h 39m
$577
St. LouisCartagena
STL - CTG
STLCTG
Lambert-St Louis
Tue 4/14
6:00 am-1:20 pm
1 stop7h 20m
Cartagena Rafael Nunez
Tue 4/21
2:35 pm-11:36 pm
1 stop9h 01m
$586
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Thu 4/2
4:54 pm-12:52 pm
1 stop19h 58m
Medellín Jose Maria Cordova Intl
Sun 4/5
10:49 am-7:51 am
1 stop21h 02m
$587
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Tue 8/4
5:17 am-12:51 pm
1 stop7h 34m
Medellín Jose Maria Cordova Intl
Tue 8/11
1:50 pm-10:58 am
1 stop21h 08m
$592
St. LouisMedellín
STL - MDE
STLMDE
Lambert-St Louis
Sat 5/16
7:00 am-8:15 pm
2 stops13h 15m
Medellín Jose Maria Cordova Intl
Sat 5/23
6:00 am-9:37 pm
2 stops15h 37m
$605
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from St. Louis to South America
Have a flexible travel schedule? Discover the best time to fly to South America from St. Louis with our price prediction graph.
STL-MDE
STL-BOG
STL-CTG
STL-GRU
STL-CUZ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to South America
STL-0SA
STL-MDE
STL-BOG
STL-CTG
STL-GRU
What is the cheapest month to book a flight from St. Louis to South America?
Currently, October is the cheapest month in which you can book a flight from St. Louis to South America (average of $307). Flying from St. Louis to South America in December is currently the most expensive (average of $568). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated March 12, 2026.
Peruse reviews from past customers who have flown with Delta,LATAM Airlines, andUnited Airlines from St. Louis to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Overall
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Overall
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Overall
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Overall
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Overall
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Overall
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for St. Louis to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to South America by cabin class
Find flights from St. Louis to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and South America flights
Browse other St. Louis and South America flight options. Last updated on March 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
St. Louis to South America flights
Consider these flights traveling from St. Louis to South America.
Top 5 airlines flying from St. Louis to South America
Discover the top 5 airlines that operate flights from St. Louis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$474 | Average$654 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$474 | Average$957 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$474 | Average$910 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$488 | Average$1,047 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$758 | Average$767 | FlexibilityNo cancel fee | On-time67% |