South America

$99+ Cheap flights from Spartanburg, SC to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — BOG
Oct 16 — Oct 231
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Cheap flight deals from Spartanburg to South America

Keep the following information in mind while searching for Spartanburg to South America flight deals. Data was last updated September 16, 2025.

Round-trip from

$245
(Cheapflightsfares)

One-way from

$99
(Cheapflightsfares)

Popular in

October

Cheapest in

April

Average price

$763
From Spartanburg to South America
One-way flight from Spartanburg to South America
High demand for flights, 3% potential price rise
Cheapest flight prices on average. 2% potential price decrease ($28 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from Spartanburg to South America

Cheapest flights from Spartanburg to South America
Explore the most affordable flight options available from Spartanburg to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/511:00 amCLT - MDE
1 stop7h 04mSpirit Airlines
Mon 11/106:59 pmMDE - CLT
1 stop14h 28mSpirit Airlines
Deal found 9/14$245
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/303:09 pmCLT - MDE
1 stop10h 12mSpirit Airlines
Thu 11/63:11 pmMDE - CLT
1 stop9h 48mSpirit Airlines
Deal found 9/15$248
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/183:09 pmCLT - MDE
1 stop10h 12mSpirit Airlines
Wed 10/291:16 amMDE - CLT
1 stop7h 08mSpirit Airlines
Deal found 9/14$259
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:49 pmCLT - MDE
1 stop7h 32mSpirit Airlines
Wed 10/291:16 amMDE - CLT
1 stop7h 08mSpirit Airlines
Deal found 9/14$260
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/183:09 pmCLT - MDE
1 stop10h 12mSpirit Airlines
Fri 10/241:16 amMDE - CLT
1 stop7h 08mSpirit Airlines
Deal found 9/14$263
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/75:45 amCLT - MDE
1 stop12h 19mSpirit Airlines
Tue 11/116:59 pmMDE - CLT
1 stop14h 28mSpirit Airlines
Deal found 9/14$264
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:45 amCLT - CTG
1 stop7h 40mSpirit Airlines
Sat 10/251:32 pmCTG - CLT
1 stop6h 27mSpirit Airlines
Deal found 9/15$265
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:45 amCLT - BOG
1 stop8h 25mSpirit Airlines
Mon 10/132:10 pmBOG - CLT
1 stop8h 18mSpirit Airlines
Deal found 9/15$266
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/295:45 amCLT - BOG
1 stop8h 30mSpirit Airlines
Fri 11/73:05 pmBOG - CLT
1 stop18h 22mSpirit Airlines
Deal found 9/14$273
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/183:09 pmCLT - MDE
1 stop10h 12mSpirit Airlines
Fri 10/312:22 pmMDE - CLT
1 stop8h 06mSpirit Airlines
Deal found 9/14$280
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:49 pmCLT - MDE
1 stop7h 32mSpirit Airlines
Fri 10/312:22 pmMDE - CLT
1 stop8h 06mSpirit Airlines
Deal found 9/14$281
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/89:46 pmCLT - MDE
2 stops16h 30mSpirit Airlines
Tue 11/116:59 pmMDE - CLT
1 stop14h 28mSpirit Airlines
Deal found 9/14$282

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Spartanburg to South America that are best for you.

Fly from

Spartanburg

Fly to

South America

Route

Depart

Return

Price

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 11/5

5:45 am-6:04 pm

1 stop12h 19m

Medellín Jose Maria Cordova Intl

Mon 11/10

6:59 pm-9:27 am

1 stop14h 28m

$245

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 11/8

9:49 am-6:04 pm

1 stop8h 15m

Medellín Jose Maria Cordova Intl

Tue 11/11

6:59 pm-9:27 am

1 stop14h 28m

$245

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Wed 10/29

5:45 am-1:15 pm

1 stop8h 30m

Bogotá El Dorado

Thu 11/6

3:05 pm-12:59 am

1 stop9h 54m

$284

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Tue 10/21

5:45 am-12:21 am

1 stop19h 36m

Medellín Jose Maria Cordova Intl

Sun 10/26

1:16 am-10:16 am

1 stop8h 00m

$313

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Wed 2/4

5:06 pm-6:10 pm

1 stop25h 04m

Bogotá El Dorado

Wed 2/11

9:15 am-8:41 pm

1 stop11h 26m

$322

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Wed 11/5

5:45 am-1:08 pm

1 stop7h 23m

Cartagena Rafael Nunez

Mon 11/10

2:16 pm-12:59 am

1 stop10h 43m

$335

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 10/29

2:40 pm-12:21 am

2 stops10h 41m

Medellín Jose Maria Cordova Intl

Thu 11/6

3:11 pm-8:37 am

2 stops17h 26m

$346

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Tue 10/21

2:40 pm-12:21 am

2 stops10h 41m

Medellín Jose Maria Cordova Intl

Mon 10/27

1:16 am-11:28 pm

1 stop21h 12m

$348

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 11/8

9:46 pm-2:16 pm

2 stops16h 30m

Medellín Jose Maria Cordova Intl

Mon 11/10

4:48 am-12:59 am

2 stops20h 11m

$368

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 10/13

5:49 pm-12:21 am

1 stop7h 32m

Medellín Jose Maria Cordova Intl

Mon 10/20

2:22 pm-11:28 pm

1 stop8h 06m

$371

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 60 results
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Best time to book a flight from Spartanburg to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to South America

What is the cheapest month to book a flight from Spartanburg to South America?

Currently, May is the cheapest month in which you can book a flight from Spartanburg to South America (average of $359). Flying from Spartanburg to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to SA?

Find hourly flight availability from Spartanburg to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Spartanburg to South America as you normally would.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 16, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and GOL from Spartanburg to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Spartanburg to South America?

    Departing from Spartanburg to South America will take you 12h 19m. There are 2037 mi between Spartanburg and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Spartanburg to South America?

  • Can I find deals for flights from Spartanburg to South America that include hotel bookings?

    Yes. In addition to deals on Spartanburg to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to South America.

  • Can I find deals for business class flights from Spartanburg to South America?

    Yes. Cheapflights offers flight deals from Spartanburg to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to South America?

    Currently, May is the cheapest month in which you can book a flight from Spartanburg to South America (average of $359). Flying from Spartanburg to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Spartanburg to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Spartanburg to South America

Discover the top 6 airlines that operate flights from Spartanburg to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$247Average$434FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$384Average$865FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$449Average$868FlexibilityNo cancel feeOn-time71%
DeltaCheapest$452Average$908FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$482Average$842FlexibilityNo cancel feeOn-time81%
GOLCheapest$667Average$929FlexibilityNo cancel feeOn-time74%

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