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South America

$95+ Cheap flights from Spartanburg, SC to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — BOG
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Spartanburg to South America

Cheapest flights from Spartanburg to South America
Explore the most affordable flight options available from Spartanburg to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Expedia deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:55 am
CLT
-
MDE
1 stop8h 18m
Spirit Airlines
Wed 3/43:15 pm
MDE
-
CLT
1 stop8h 41m
Spirit Airlines
Deal found 1/28$234
This Orbitz deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:55 am
CLT
-
MDE
1 stop8h 18m
Spirit Airlines
Thu 3/53:15 pm
MDE
-
CLT
1 stop8h 41m
Spirit Airlines
Deal found 1/28$237
This FlightHub deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/86:00 am
CLT
-
CTG
1 stop7h 10m
Spirit Airlines
Wed 2/112:21 pm
CTG
-
CLT
1 stop10h 19m
Spirit Airlines
Deal found 1/28$238
This Orbitz deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/229:22 pm
CLT
-
MDE
1 stop17h 00m
Spirit Airlines
Wed 4/12:17 pm
MDE
-
CLT
1 stop9h 21m
Spirit Airlines
Deal found 1/28$242
This Expedia deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/225:55 am
CLT
-
CTG
1 stop7h 15m
Spirit Airlines
Thu 2/262:21 pm
CTG
-
CLT
1 stop9h 35m
Spirit Airlines
Deal found 1/27$242
This Travelocity deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:55 am
CLT
-
MDE
1 stop8h 18m
Spirit Airlines
Wed 3/43:15 pm
MDE
-
CLT
1 stop8h 41m
Spirit Airlines
Deal found 1/28$243
This Orbitz deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:55 am
CLT
-
CTG
1 stop7h 15m
Spirit Airlines
Thu 3/52:21 pm
CTG
-
CLT
1 stop9h 35m
Spirit Airlines
Deal found 1/28$243
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
CLT
-
GYE
1 stop18h 01m
Spirit Airlines
Tue 5/511:59 pm
GYE
-
CLT
1 stop13h 14m
Spirit Airlines
Deal found 1/27$245
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:24 pm
CLT
-
MDE
1 stop11h 57m
Spirit Airlines
Sun 4/52:17 pm
MDE
-
CLT
1 stop9h 21m
Spirit Airlines
Deal found 1/28$251
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
CLT
-
MDE
1 stop8h 22m
Spirit Airlines
Tue 4/142:17 pm
MDE
-
CLT
1 stop9h 21m
Spirit Airlines
Deal found 1/27$253
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:55 am
CLT
-
MDE
1 stop8h 18m
Spirit Airlines
Sat 3/73:15 pm
MDE
-
CLT
1 stop8h 41m
Spirit Airlines
Deal found 1/27$254
This CheapOair deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:00 am
CLT
-
GYE
1 stop18h 04m
Spirit Airlines
Mon 3/2311:59 pm
GYE
-
CLT
1 stop19h 24m
Spirit Airlines
Deal found 1/28$254

Find flight deals from Spartanburg to South America

Keep the following information in mind while searching for Spartanburg to South America flight deals. Data was last updated January 29, 2026.

Round-trip from

$234
(Expedia)

One-way from

$95
(Kiwi.com)

Popular in

January

Cheapest in

February

Average price

$806
From Spartanburg to South America
Search Deals
One-way flight from Spartanburg to South America
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($58 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Spartanburg to South America that are best for you.

Fly from

Spartanburg

Fly to

South America

Route

Depart

Return

Price

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Sun 2/8

6:00 am-1:10 pm

1 stop7h 10m

Cartagena Rafael Nunez

Wed 2/11

2:21 pm-12:40 am

1 stop10h 19m

$238

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 3/14

9:22 pm-1:22 pm

1 stop17h 00m

Medellín Jose Maria Cordova Intl

Tue 3/17

2:17 pm-12:38 am

1 stop9h 21m

$242

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 3/2

5:55 am-2:13 pm

1 stop8h 18m

Medellín Jose Maria Cordova Intl

Thu 3/5

3:15 pm-8:26 am

1 stop17h 11m

$242

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Thu 4/2

1:24 pm-12:21 am

1 stop11h 57m

Medellín Jose Maria Cordova Intl

Thu 4/9

2:17 pm-12:38 am

1 stop9h 21m

$242

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sun 3/22

9:22 pm-1:22 pm

1 stop17h 00m

Medellín Jose Maria Cordova Intl

Wed 4/1

2:17 pm-12:38 am

1 stop9h 21m

$242

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Sun 3/1

5:55 am-1:10 pm

1 stop7h 15m

Cartagena Rafael Nunez

Thu 3/5

2:21 pm-11:56 pm

1 stop9h 35m

$243

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Tue 4/28

8:55 am-11:01 pm

1 stop15h 06m

Guayaquil Jose Joaquin de Olmedo

Wed 5/6

11:59 pm-2:13 pm

1 stop13h 14m

$245

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Tue 4/28

6:00 am-11:01 pm

1 stop18h 01m

Guayaquil Jose Joaquin de Olmedo

Tue 5/5

11:59 pm-2:13 pm

1 stop13h 14m

$245

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Tue 4/28

8:55 am-12:42 am

1 stop16h 47m

Medellín Jose Maria Cordova Intl

Tue 5/5

1:37 am-2:13 pm

1 stop11h 36m

$251

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Fri 3/6

5:55 am-2:13 pm

1 stop8h 18m

Medellín Jose Maria Cordova Intl

Wed 3/18

2:17 pm-8:21 am

1 stop17h 04m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 60 results
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2
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6

Best time to book a flight from Spartanburg to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to South America

What is the cheapest month to book a flight from Spartanburg to South America?

Currently, October is the cheapest month in which you can book a flight from Spartanburg to South America (average of $96). Flying from Spartanburg to South America in June is currently the most expensive (average of $431). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to SA?

Find hourly flight availability from Spartanburg to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 31% on flights from Spartanburg to South America by exploring options for tickets in the evening.

What is the cheapest day to fly from Spartanburg to South America?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to South America. Price data was last updated on March 23, 2025.

Travelers seeking maximum savings on their Spartanburg to South America flight should consider departing on Tuesday evenings when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 29, 2026.
See what other customers who have flown with Delta, LATAM Airlines, and GOL from Spartanburg to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,125 reviews

Entertainment

7.8

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,125 reviews
Delta
7.9
Good
8,125 reviews

Entertainment

7.8

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,918 reviews
Delta
7.9
Good
8,125 reviews

Entertainment

7.8

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
GOL
7.3
Good
1,160 reviews
Delta
7.9
Good
8,125 reviews

Entertainment

7.8

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,206 reviews
Delta
7.9
Good
8,125 reviews

Entertainment

7.8

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,394 reviews
Delta
7.9
Good
8,125 reviews

Entertainment

7.8

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Spartanburg to South America?

    Departing from Spartanburg to South America will take you 7h 10m. There are 1745 mi between Spartanburg and South America.

  • What are the cheapest airlines to fly from Spartanburg to South America one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $101. Users have also found prices from $189 and $271 on Avianca and GOL, respectively.

  • What are the most popular routes from Spartanburg to South America?

    When deciding which route to take from Spartanburg to South America consider Charlotte Douglas - Medellín Jose Maria Cordova Intl, Charlotte Douglas - Lima J Chavez Intl or Charlotte Douglas - Bogotá El Dorado as they are the most popular.

  • Can I find deals for flights from Spartanburg to South America that include hotel bookings?

    Yes. In addition to deals on Spartanburg to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to South America.

  • Can I find deals for business class flights from Spartanburg to South America?

    Yes. Cheapflights offers flight deals from Spartanburg to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to South America?

    Currently, October is the cheapest month in which you can book a flight from Spartanburg to South America (average of $96). Flying from Spartanburg to South America in June is currently the most expensive (average of $431). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Spartanburg to South America

Discover the top 6 airlines that operate flights from Spartanburg to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$149Average$411FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$424Average$503FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$435Average$928FlexibilityNo cancel feeOn-time71%
DeltaCheapest$452Average$989FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$487Average$822FlexibilityNo cancel feeOn-time81%
GOLCheapest$667Average$878FlexibilityNo cancel feeOn-time74%

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