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South America

$101+ Cheap flights from Spartanburg, SC to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — BOG
Dec 2 — Dec 91
Tue 12/2
Tue 12/9
1 adult, Economy
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Find flight deals from Spartanburg to South America

Cheapest flights from Spartanburg to South America
Explore the most affordable flight options available from Spartanburg to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 2, 2025.

This Expedia deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:58 pmCLT - MDE
1 stop10h 11mSpirit Airlines
Mon 12/153:10 pmMDE - CLT
1 stop8h 49mSpirit Airlines
Deal found 11/1$250
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/122:58 pmCLT - MDE
1 stop10h 11mSpirit Airlines
Sat 12/132:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 11/1$259
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:58 pmCLT - MDE
1 stop10h 11mSpirit Airlines
Wed 12/172:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 11/1$264
This Expedia deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:11 pmCLT - MDE
1 stop9h 45mSpirit Airlines
Wed 12/102:05 amMDE - CLT
1 stop11h 58mSpirit Airlines
Deal found 11/1$274
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/82:58 pmCLT - MDE
1 stop10h 11mSpirit Airlines
Wed 12/172:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 11/1$280
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/122:58 pmCLT - MDE
1 stop10h 11mSpirit Airlines
Fri 12/192:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 11/1$284
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:55 pmCLT - BOG
1 stop15h 57mSpirit Airlines
Wed 2/43:05 pmBOG - CLT
1 stop9h 54mSpirit Airlines
Deal found 11/1$287
This Expedia deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/78:55 pmCLT - MDE
1 stop14h 00mSpirit Airlines
Fri 12/122:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 10/30$292
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:58 pmCLT - MDE
1 stop10h 11mSpirit Airlines
Thu 12/183:10 pmMDE - CLT
1 stop8h 19mSpirit Airlines
Deal found 11/1$298
This Expedia deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:58 pmCLT - MDE
1 stop10h 11mSpirit Airlines
Fri 12/122:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 10/31$299
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:59 pmCLT - MDE
1 stop6h 57mSpirit Airlines
Fri 12/122:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 11/1$300
This Expedia deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/157:00 amCLT - CTG
1 stop6h 10mSpirit Airlines
Thu 12/182:15 pmCTG - CLT
1 stop6h 18mSpirit Airlines
Deal found 11/1$300

Cheap flight deals from Spartanburg to South America

Keep the following information in mind while searching for Spartanburg to South America flight deals. Data was last updated November 2, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$250
(Expedia)

One-way from

$101
(Spirit)

Popular in

December

Cheapest in

April

Average price

$822
Provider with most accurate pricing for Charlotte Douglas-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Sao Paulo (SAO) flights.
Search Deals
From Spartanburg to South America
Search Deals
One-way flight from Spartanburg to South America
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
Use the filters below to find and compare flights from Spartanburg to South America that are best for you.

Fly from

Spartanburg

Fly to

South America

Route

Depart

Return

Price

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Tue 12/2

3:11 pm-12:56 am

1 stop9h 45m

Medellín Jose Maria Cordova Intl

Sat 12/13

2:05 am-9:39 am

1 stop7h 34m

$300

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 12/6

2:57 pm-1:09 am

1 stop10h 12m

Medellín Jose Maria Cordova Intl

Thu 12/11

2:05 am-2:03 pm

1 stop11h 58m

$307

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Tue 12/2

7:30 am-1:25 pm

1 stop5h 55m

Cartagena Rafael Nunez

Tue 12/9

2:15 pm-11:59 pm

1 stop9h 44m

$312

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Tue 12/9

2:58 pm-1:09 am

1 stop10h 11m

Medellín Jose Maria Cordova Intl

Tue 12/16

2:05 am-2:03 pm

1 stop11h 58m

$318

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Thu 12/11

2:58 pm-1:10 pm

1 stop22h 12m

Cartagena Rafael Nunez

Sat 12/20

2:15 pm-11:29 pm

1 stop9h 14m

$325

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 12/1

5:59 pm-12:56 am

1 stop6h 57m

Medellín Jose Maria Cordova Intl

Fri 12/12

11:50 am-11:59 pm

2 stops12h 09m

$326

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Fri 12/5

2:58 pm-1:09 am

1 stop10h 11m

Medellín Jose Maria Cordova Intl

Sat 12/13

2:05 am-9:39 am

1 stop7h 34m

$327

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Fri 12/5

2:58 pm-1:09 am

1 stop10h 11m

Medellín Jose Maria Cordova Intl

Thu 12/11

2:05 am-9:39 am

1 stop7h 34m

$327

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Fri 12/12

8:54 am-1:10 pm

1 stop28h 16m

Cartagena Rafael Nunez

Mon 12/15

2:15 pm-11:59 pm

1 stop9h 44m

$330

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Fri 12/12

2:58 pm-1:09 am

1 stop10h 11m

Medellín Jose Maria Cordova Intl

Wed 12/17

11:50 am-11:59 pm

2 stops12h 09m

$332

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 60 results
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6

Best time to book a flight from Spartanburg to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to South America

What is the cheapest month to book a flight from Spartanburg to South America?

Currently, October is the cheapest month in which you can book a flight from Spartanburg to South America (average of $96). Flying from Spartanburg to South America in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to SA?

Find hourly flight availability from Spartanburg to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 2, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 10% on flights from Spartanburg to South America by exploring options for tickets in the evening.

What is the cheapest day to fly from Spartanburg to South America?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Spartanburg to South America flight should consider departing on Sunday evenings when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated November 2, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and GOL from Spartanburg to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Boarding

8.2

Overall

7.9

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Boarding

8.2

Overall

7.9

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
LATAM Airlines
7.5
Good
1,873 reviews
Delta
7.9
Good
8,001 reviews

Boarding

8.2

Overall

7.9

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
GOL
7.3
Good
1,122 reviews
Delta
7.9
Good
8,001 reviews

Boarding

8.2

Overall

7.9

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
American Airlines
7.2
Good
11,036 reviews
Delta
7.9
Good
8,001 reviews

Boarding

8.2

Overall

7.9

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Spirit Airlines
6.3
Okay
8,114 reviews
Delta
7.9
Good
8,001 reviews

Boarding

8.2

Overall

7.9

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Spartanburg to South America?

    Departing from Spartanburg to South America will take you 9h 45m. There are 2037 mi between Spartanburg and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Spartanburg to South America?

    When deciding which route to take from Spartanburg to South America consider Charlotte Douglas - Medellín Jose Maria Cordova Intl, Charlotte Douglas - Lima J Chavez Intl or Charlotte Douglas - Bogotá El Dorado as they are the most popular.

  • Can I find deals for flights from Spartanburg to South America that include hotel bookings?

    Yes. In addition to deals on Spartanburg to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to South America.

  • Can I find deals for business class flights from Spartanburg to South America?

    Yes. Cheapflights offers flight deals from Spartanburg to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to South America?

    Currently, October is the cheapest month in which you can book a flight from Spartanburg to South America (average of $96). Flying from Spartanburg to South America in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Spartanburg to South America

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Top 6 airlines flying from Spartanburg to South America

Discover the top 6 airlines that operate flights from Spartanburg to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$251Average$433FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$394Average$764FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$441Average$881FlexibilityNo cancel feeOn-time71%
DeltaCheapest$449Average$933FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$482Average$850FlexibilityNo cancel feeOn-time81%
GOLCheapest$667Average$878FlexibilityNo cancel feeOn-time74%

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