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South America

$104+ Cheap flights from Spartanburg, SC to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — BOG
Jan 16 — Jan 231
Fri 1/16
Fri 1/23
1 adult, Economy
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Cheap flight deals from Spartanburg to South America

Cheapest flights from Spartanburg to South America
Explore the most affordable flight options available from Spartanburg to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 17, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:34 pmCLT - MDE
1 stop16h 23mSpirit Airlines
Thu 1/293:15 pmMDE - CLT
1 stop9h 25mSpirit Airlines
Deal found 12/15$355
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:43 pmCLT - MDE
1 stop13h 12mMultiple Airlines
Thu 1/2910:10 amMDE - CLT
2 stops23h 20mMultiple Airlines
Deal found 12/15$424
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:00 amCLT - GYE
1 stop16h 53mSpirit Airlines
Thu 2/51:26 amGYE - CLT
2 stops15h 28mSpirit Airlines
Deal found 12/16$471
This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:34 pmCLT - MDE
1 stop16h 23mSpirit Airlines
Sun 12/212:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 12/15$475
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:34 pmCLT - MDE
1 stop13h 21mSpirit Airlines
Wed 12/312:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 12/15$485
This Priceline deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:34 pmCLT - MDE
1 stop13h 21mSpirit Airlines
Tue 1/62:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 12/16$496
This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:34 pmCLT - MDE
1 stop13h 21mSpirit Airlines
Tue 12/302:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 12/17$499
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:38 pmCLT - MDE
1 stop16h 36mSpirit Airlines
Tue 1/62:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 12/16$504
This KAYAK deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:34 pmCLT - CTG
2 stops39h 36mSpirit Airlines
Fri 12/262:15 pmCTG - CLT
1 stop6h 18mSpirit Airlines
Deal found 12/17$525
This Spirit deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:34 pmCLT - MDE
1 stop13h 21mSpirit Airlines
Sat 1/103:15 pmMDE - CLT
1 stop9h 25mSpirit Airlines
Deal found 12/17$526
This FlightHub deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:00 amCLT - CTG
1 stop6h 10mSpirit Airlines
Mon 12/292:15 pmCTG - CLT
1 stop6h 18mSpirit Airlines
Deal found 12/16$529
This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:34 pmCLT - MDE
1 stop13h 21mSpirit Airlines
Fri 12/262:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 12/15$533

Find flight deals from Spartanburg to South America

Keep the following information in mind while searching for Spartanburg to South America flight deals. Data was last updated December 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$202
(Priceline)

One-way from

$104
(Cheapflightsfares)

Popular in

December

Cheapest in

April

Average price

$1,745
Provider with most accurate pricing for Charlotte Douglas-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Sao Paulo (SAO) flights.
Search Deals
From Spartanburg to South America
Search Deals
One-way flight from Spartanburg to South America
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($350 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($65 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
Use the filters below to find and compare flights from Spartanburg to South America that are best for you.

Fly from

Spartanburg

Fly to

South America

Route

Depart

Return

Price

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 1/29

1:24 pm-12:21 am

1 stop10h 57m

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

1:26 am-6:48 pm

1 stop17h 22m

$235

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Sat 1/31

6:00 am-1:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

Tue 2/3

2:21 pm-12:40 am

1 stop10h 19m

$237

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Fri 1/30

6:00 am-1:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

Fri 2/6

2:21 pm-12:40 am

1 stop10h 19m

$238

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Fri 1/16

7:43 pm-12:21 am

1 stop28h 38m

Guayaquil Jose Joaquin de Olmedo

Sat 1/24

1:26 am-9:47 pm

1 stop20h 21m

$243

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 1/7

9:00 am-11:53 pm

1 stop14h 53m

Guayaquil Jose Joaquin de Olmedo

Tue 1/27

1:26 am-10:55 am

1 stop9h 29m

$253

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 2/5

1:24 pm-12:21 am

1 stop10h 57m

Guayaquil Jose Joaquin de Olmedo

Wed 2/18

12:59 am-6:02 pm

1 stop17h 03m

$257

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Fri 1/16

11:12 am-12:21 am

2 stops13h 09m

Guayaquil Jose Joaquin de Olmedo

Fri 1/30

1:26 am-10:55 am

1 stop9h 29m

$261

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Thu 2/5

1:24 pm-1:15 pm

1 stop23h 51m

Cartagena Rafael Nunez

Tue 2/10

2:21 pm-12:40 am

1 stop10h 19m

$261

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Thu 2/5

7:43 pm-1:15 pm

1 stop17h 32m

Cartagena Rafael Nunez

Mon 2/9

2:21 pm-12:40 am

1 stop10h 19m

$273

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Thu 1/15

7:43 pm-1:15 pm

1 stop17h 32m

Cartagena Rafael Nunez

Thu 1/22

2:21 pm-12:40 am

1 stop10h 19m

$273

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 60 results
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6

Best time to book a flight from Spartanburg to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to South America

What is the cheapest month to book a flight from Spartanburg to South America?

Currently, October is the cheapest month in which you can book a flight from Spartanburg to South America (average of $96). Flying from Spartanburg to South America in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to SA?

Find hourly flight availability from Spartanburg to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 17, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 7% on flights from Spartanburg to South America by exploring options for tickets in the evening.

What is the cheapest day to fly from Spartanburg to South America?

Use this chart to determine the cheapest time to fly round-trip from Spartanburg to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Spartanburg to South America flight should consider departing on Friday afternoons when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 17, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and GOL from Spartanburg to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,891 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
GOL
7.3
Good
1,131 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,049 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,186 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Spartanburg to South America?

    Departing from Spartanburg to South America will take you 10h 57m. There are 2582 mi between Spartanburg and South America.

  • What are the cheapest airlines to fly from Spartanburg to South America one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $100. Users have also found prices from $248 and $271 on Avianca and GOL, respectively.

  • What are the most popular routes from Spartanburg to South America?

    When deciding which route to take from Spartanburg to South America consider Charlotte Douglas - Medellín Jose Maria Cordova Intl, Charlotte Douglas - Lima J Chavez Intl or Charlotte Douglas - Bogotá El Dorado as they are the most popular.

  • Can I find deals for flights from Spartanburg to South America that include hotel bookings?

    Yes. In addition to deals on Spartanburg to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to South America.

  • Can I find deals for business class flights from Spartanburg to South America?

    Yes. Cheapflights offers flight deals from Spartanburg to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to South America?

    Currently, October is the cheapest month in which you can book a flight from Spartanburg to South America (average of $96). Flying from Spartanburg to South America in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Spartanburg to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Spartanburg to South America

Discover the top 6 airlines that operate flights from Spartanburg to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$149Average$427FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$394Average$793FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$444Average$919FlexibilityNo cancel feeOn-time71%
DeltaCheapest$452Average$976FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$470Average$814FlexibilityNo cancel feeOn-time81%
GOLCheapest$664Average$927FlexibilityNo cancel feeOn-time74%

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