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South America

$768+ Cheap flights from Sioux Falls (FSD) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — BOG
Oct 14 — Oct 211
Tue 10/14
Tue 10/21
1 adult, Economy
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Cheap flight deals from Sioux Falls to South America

Keep the following information in mind while searching for Sioux Falls to South America flight deals. Data was last updated September 14, 2025.

Round-trip from

$768
(American Airlines)
From Sioux Falls Joe Foss Field to South America
Search Deals

Find flight deals from Sioux Falls to South America

Cheapest flights from Sioux Falls to South America
Explore the most affordable flight options available from Sioux Falls to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/31:03 pmFSD - SCL
1 stop15h 52mAmerican Airlines
Thu 11/1310:25 pmSCL - FSD
2 stops25h 45mAmerican Airlines
Deal found 9/13$768
This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:05 amFSD - SCL
2 stops30h 25mLATAM Airlines
Thu 12/115:15 amSCL - FSD
2 stops20h 58mLATAM Airlines
Deal found 9/11$784
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/88:00 amFSD - SCL
3 stops21h 50mUnited Airlines
Thu 12/1110:45 pmSCL - FSD
2 stops17h 06mUnited Airlines
Deal found 9/11$838
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/35:30 amFSD - SCL
1 stop23h 10mDelta
Wed 11/1212:55 amSCL - FSD
2 stops25h 16mDelta
Deal found 9/13$874
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/81:09 pmFSD - SCL
1 stop15h 41mAmerican Airlines
Thu 12/1111:15 pmSCL - FSD
1 stop16h 03mAmerican Airlines
Deal found 9/11$944
This FlightHub deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/35:30 amFSD - SCL
1 stop23h 10mLATAM Airlines
Thu 11/1311:10 pmSCL - FSD
1 stop27h 01mLATAM Airlines
Deal found 9/13$948
This KAYAK deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:05 amFSD - GRU
2 stops24h 45mLATAM Airlines
Tue 1/2012:55 pmGRU - FSD
2 stops36h 21mLATAM Airlines
Deal found 9/13$1,203
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/181:16 pmFSD - GRU
1 stop15h 54mAmerican Airlines
Tue 1/2011:00 pmGRU - FSD
1 stop20h 46mAmerican Airlines
Deal found 9/12$1,899
This deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/183:08 pmFSD - GRU
1 stop13h 07mUnited Airlines
Tue 1/209:45 pmGRU - FSD
1 stop16h 02mUnited Airlines
Deal found 9/11$2,002

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
Use the filters below to find and compare flights from Sioux Falls to South America that are best for you.

Fly from

Sioux Falls

Fly to

South America

Route

Depart

Return

Price

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Mon 11/3

10:59 am-9:00 am

2 stops19h 01m

Santiago Arturo Merino Benitez

Thu 11/13

10:25 pm-1:13 pm

2 stops17h 48m

$768

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Wed 1/14

6:47 am-9:05 am

2 stops23h 18m

Santiago Arturo Merino Benitez

Thu 1/22

11:55 pm-4:31 pm

2 stops19h 36m

$768

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Mon 12/8

5:05 am-2:30 pm

2 stops30h 25m

Santiago Arturo Merino Benitez

Thu 12/11

5:15 am-11:13 pm

2 stops20h 58m

$784

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Mon 12/8

8:00 am-8:50 am

3 stops21h 50m

Santiago Arturo Merino Benitez

Thu 12/11

10:45 pm-12:51 pm

2 stops17h 06m

$838

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Mon 11/3

5:30 am-7:40 am

1 stop23h 10m

Santiago Arturo Merino Benitez

Wed 11/12

12:55 am-11:11 pm

2 stops25h 16m

$874

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Mon 12/8

1:09 pm-7:50 am

1 stop15h 41m

Santiago Arturo Merino Benitez

Thu 12/11

11:15 pm-12:18 pm

1 stop16h 03m

$944

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Mon 11/3

5:30 am-7:40 am

1 stop23h 10m

Santiago Arturo Merino Benitez

Thu 11/13

11:10 pm-11:11 pm

1 stop27h 01m

$948

Sioux FallsSao Paulo

FSD - GRU

FSDGRU

Sioux Falls Joe Foss Field

Tue 1/13

7:30 am-7:15 am

1 stop20h 45m

Sao Paulo Guarulhos Intl

Tue 2/17

9:45 pm-10:32 am

1 stop15h 47m

$1,040

Sioux FallsSao Paulo

FSD - GRU

FSDGRU

Sioux Falls Joe Foss Field

Tue 1/13

10:58 am-9:35 am

2 stops19h 37m

Sao Paulo Guarulhos Intl

Tue 2/17

9:30 pm-3:33 pm

2 stops21h 03m

$1,044

Sioux FallsSao Paulo

FSD - GRU

FSDGRU

Sioux Falls Joe Foss Field

Tue 1/13

12:27 pm-8:05 am

2 stops16h 38m

Sao Paulo Guarulhos Intl

Tue 2/17

11:00 pm-12:12 pm

1 stop16h 12m

$1,045

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Best time to book a flight from Sioux Falls to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to South America

What is the cheapest month to book a flight from Sioux Falls to South America?

Currently, May is the cheapest month in which you can book a flight from Sioux Falls to South America (average of $359). Flying from Sioux Falls to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 14, 2025.
Peruse reviews from past customers who have flown with American Airlines from Sioux Falls to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Comfort

7.2

Overall

7.2

Crew

8.0

Food

6.4

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Comfort

7.2

Overall

7.2

Crew

8.0

Food

6.4

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to South America?

    If you book a flight to South America from Sioux Falls, you will be flying from Joe Foss Field, which is the city’s only airport. Sioux Falls Joe Foss Field (FSD) is located 2.6 mi from the center of Sioux Falls.

  • How long is the flight from Sioux Falls to South America?

    For as low as $768, American Airlines can have you in South America from Sioux Falls in 19h 01m. There are 5561 mi between Sioux Falls and South America. This flight may include one or multiple stops.

  • Can I find deals for flights from Sioux Falls to South America that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to South America.

  • Can I find deals for business class flights from Sioux Falls to South America?

    Yes. Cheapflights offers flight deals from Sioux Falls to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to South America?

    Currently, May is the cheapest month in which you can book a flight from Sioux Falls to South America (average of $359). Flying from Sioux Falls to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Sioux Falls to South America

Discover the top airline that operate flights from Sioux Falls to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$652Average$863FlexibilityNo cancel feeOn-time71%

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