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South America

$863+ Cheap flights from Sioux Falls (FSD) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — BOG
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Sioux Falls to South America

Cheapest flights from Sioux Falls to South America
Explore the most affordable flight options available from Sioux Falls to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:44 am
FSD
-
SCL
1 stop23h 16m
American Airlines
Mon 3/309:25 pm
SCL
-
FSD
2 stops27h 30m
American Airlines
Deal found 1/25$863
This LATAM Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:10 am
FSD
-
SCL
2 stops23h 35m
LATAM Airlines
Wed 3/2512:20 am
SCL
-
FSD
2 stops23h 52m
LATAM Airlines
Deal found 1/25$873
This Orbitz deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:10 am
FSD
-
SCL
3 stops31h 00m
LATAM Airlines
Mon 3/305:30 pm
SCL
-
FSD
2 stops30h 42m
LATAM Airlines
Deal found 1/25$893
This KAYAK deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:25 am
FSD
-
GRU
2 stops24h 25m
LATAM Airlines
Mon 10/1211:45 pm
GRU
-
FSD
2 stops24h 27m
LATAM Airlines
Deal found 1/27$1,119
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/81:33 pm
FSD
-
GRU
1 stop17h 27m
American Airlines
Mon 10/1210:00 pm
GRU
-
FSD
1 stop16h 19m
American Airlines
Deal found 1/27$1,122
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:16 pm
FSD
-
GRU
2 stops16h 14m
United Airlines
Mon 8/179:50 pm
GRU
-
FSD
2 stops24h 56m
United Airlines
Deal found 1/25$1,127
This KAYAK deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:25 am
FSD
-
GRU
2 stops20h 55m
LATAM Airlines
Mon 11/2310:50 pm
GRU
-
FSD
2 stops26h 22m
LATAM Airlines
Deal found 1/27$1,159
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:15 am
FSD
-
GRU
2 stops21h 05m
Delta
Mon 11/2311:45 pm
GRU
-
FSD
1 stop25h 27m
Delta
Deal found 1/27$1,172
This Ovago deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1811:21 am
FSD
-
GRU
1 stop16h 54m
Copa Airlines
Thu 2/269:45 pm
GRU
-
FSD
1 stop19h 55m
Copa Airlines
Deal found 1/27$1,295
This Ovago deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:08 am
FSD
-
GRU
1 stop25h 27m
LATAM Airlines
Thu 2/2610:15 am
GRU
-
FSD
2 stops26h 53m
LATAM Airlines
Deal found 1/27$1,297
This Ovago deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/181:40 pm
FSD
-
GRU
2 stops16h 50m
Multiple Airlines
Thu 2/2610:25 pm
GRU
-
FSD
2 stops19h 15m
Multiple Airlines
Deal found 1/27$1,300
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:30 am
FSD
-
GRU
1 stop23h 00m
American Airlines
Mon 11/2310:45 pm
GRU
-
FSD
1 stop16h 51m
American Airlines
Deal found 1/27$1,301

Find flight deals from Sioux Falls to South America

Keep the following information in mind while searching for Sioux Falls to South America flight deals. Data was last updated January 27, 2026.

Round-trip from

$863
(American Airlines)
From Sioux Falls Joe Foss Field to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Sioux Falls to South America that are best for you.

Fly from

Sioux Falls

Fly to

South America

Route

Depart

Return

Price

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Mon 3/23

1:26 pm-9:05 am

2 stops17h 39m

Santiago Arturo Merino Benitez

Mon 3/30

9:25 pm-10:55 pm

2 stops27h 30m

$863

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Tue 3/24

5:10 am-4:30 am

2 stops21h 20m

Santiago Arturo Merino Benitez

Wed 3/25

12:20 am-10:12 pm

2 stops23h 52m

$873

Sioux FallsSantiago

FSD - SCL

FSDSCL

Sioux Falls Joe Foss Field

Mon 3/23

5:10 am-2:10 pm

3 stops31h 00m

Santiago Arturo Merino Benitez

Mon 3/30

5:30 pm-10:12 pm

2 stops30h 42m

$893

Sioux FallsSao Paulo

FSD - GRU

FSDGRU

Sioux Falls Joe Foss Field

Wed 2/18

11:21 am-7:15 am

1 stop16h 54m

Sao Paulo Guarulhos Intl

Thu 2/26

9:45 pm-2:40 pm

1 stop19h 55m

$1,295

Sioux FallsSao Paulo

FSD - GRU

FSDGRU

Sioux Falls Joe Foss Field

Wed 2/18

5:08 am-9:35 am

1 stop25h 27m

Sao Paulo Guarulhos Intl

Thu 2/26

10:15 am-10:08 am

2 stops26h 53m

$1,297

Sioux FallsSao Paulo

FSD - GRU

FSDGRU

Sioux Falls Joe Foss Field

Wed 2/18

1:40 pm-9:30 am

2 stops16h 50m

Sao Paulo Guarulhos Intl

Thu 2/26

10:25 pm-2:40 pm

2 stops19h 15m

$1,300

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Best time to book a flight from Sioux Falls to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to South America
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 27, 2026.
Peruse reviews from past customers who have flown with American Airlines from Sioux Falls to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,197 reviews

Food

6.4

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,197 reviews
American Airlines
7.2
Good
11,197 reviews

Food

6.4

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to South America?

    If you book a flight to South America from Sioux Falls, you will be flying from Joe Foss Field, which is the city’s only airport. Sioux Falls Joe Foss Field (FSD) is located 2.6 mi from the center of Sioux Falls.

  • How long is the flight from Sioux Falls to South America?

    For as low as $1,295, American Airlines can have you in South America from Sioux Falls in 16h 54m. There are 5616 mi between Sioux Falls and South America. This flight may include one or multiple stops.

  • Can I find deals for flights from Sioux Falls to South America that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to South America.

  • Can I find deals for business class flights from Sioux Falls to South America?

    Yes. Cheapflights offers flight deals from Sioux Falls to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Sioux Falls to South America

Discover the top airline that operate flights from Sioux Falls to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$668Average$1,039FlexibilityNo cancel feeOn-time71%

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