$223+ Cheap flights from Columbus (CMH) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Nov 23 — Nov 301
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
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Cheapest flights from Columbus to South AmericaExplore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:13 pm -
2 stops19h 21m
Fri 12/42:36 pm -
1 stop9h 22m
Deal found 10/22![American Airlines logo]()
$535
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:18 pm -
1 stop20h 19m
Sun 12/132:36 pm -
2 stops20h 10m
Deal found 10/21![American Airlines logo]()
$547
This BusinessClass deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:34 pm -
2 stops20h 03m
Tue 12/84:37 pm -
2 stops18h 09m
Deal found 10/23![GOL logo]()
$557
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:11 pm -
2 stops17h 25m
Fri 12/112:36 pm -
1 stop9h 22m
Deal found 10/20![American Airlines logo]()
$610
This deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:38 am -
1 stop11h 27m
Tue 11/171:30 am -
1 stop9h 22m
Deal found 10/20![United Airlines logo]()
$623
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:18 pm -
1 stop20h 19m
Tue 12/84:37 pm -
2 stops17h 10m
Deal found 10/23![American Airlines logo]()
$625
This LATAM Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:05 am -
1 stop12h 25m
Thu 1/149:00 am -
2 stops15h 10m
Deal found 10/20![LATAM Airlines logo]()
$626
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:00 am -
2 stops16h 05m
Mon 11/161:30 am -
2 stops15h 19m
Deal found 10/23![United Airlines logo]()
$627
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:22 pm -
1 stop19h 18m
Mon 10/263:55 pm -
1 stop17h 15m
Deal found 10/19![Delta logo]()
$628
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:13 pm -
1 stop9h 17m
Mon 11/23:15 pm -
1 stop8h 44m
Deal found 10/20![American Airlines logo]()
$638
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:56 pm -
2 stops30h 09m
Mon 11/28:15 am -
2 stops28h 55m
Deal found 10/20![United Airlines logo]()
$642
This BusinessClass deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:11 pm -
2 stops18h 04m
Mon 12/77:50 am -
2 stops11h 50m
Deal found 10/20![GOL logo]()
$664
Best flights from Columbus to South AmericaDiscover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
Discover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/66:05 am -
1 stop7h 05m
Sun 2/142:20 pm -
1 stop9h 22m
Deal found 10/21![United Airlines logo]()
$531
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/62:48 pm -
2 stops22h 47m
Sun 2/144:35 pm -
2 stops20h 28m
Deal found 10/21![American Airlines logo]()
$535
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2712:50 pm -
1 stop25h 25m
Mon 4/52:30 pm -
1 stop17h 30m
Deal found 10/19![Delta logo]()
$539
This FlightHub deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/36:45 pm -
1 stop17h 15m
Tue 1/191:10 pm -
1 stop25h 46m
Deal found 10/23![Frontier logo]()
$621
This Air Canada deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/269:30 am -
2 stops55h 00m
Sun 4/44:30 pm -
2 stops27h 42m
Deal found 10/19![Air Canada logo]()
$628
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/210:28 am -
1 stop9h 42m
Tue 2/24:35 am -
2 stops14h 13m
Deal found 10/20![Multiple Airlines logo]()
$725
This LATAM Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:10 pm -
1 stop8h 15m
Wed 12/912:55 am -
1 stop9h 26m
Deal found 10/19![LATAM Airlines logo]()
$844
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/225:40 am -
2 stops18h 35m
Tue 5/412:55 pm -
2 stops19h 40m
Deal found 10/21![Copa Airlines logo]()
$872
This GOL deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:28 am -
1 stop20h 02m
Sat 12/1211:55 pm -
1 stop20h 33m
Deal found 10/21![GOL logo]()
$1,183
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/26:00 am -
1 stop17h 05m
Tue 2/168:15 am -
1 stop15h 29m
Deal found 10/23![United Airlines logo]()
$623
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:18 pm -
1 stop20h 19m
Tue 12/84:37 pm -
2 stops17h 10m
Deal found 10/23![American Airlines logo]()
$625
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/209:10 am -
2 stops11h 10m
Wed 4/288:30 am -
1 stop12h 20m
Deal found 10/21![United Airlines logo]()
$627
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/267:00 am -
1 stop7h 15m
Mon 4/52:30 pm -
1 stop8h 40m
Deal found 10/19![Delta logo]()
$699
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/196:00 am -
1 stop17h 05m
Sun 2/218:15 am -
1 stop15h 29m
Deal found 10/23![United Airlines logo]()
$653
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:28 am -
1 stop8h 02m
Thu 12/106:35 pm -
2 stops15h 46m
Deal found 10/19![Delta logo]()
$730
This BusinessClass deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:23 am -
2 stops18h 37m
Tue 12/81:30 am -
2 stops24h 29m
Deal found 10/22![Copa Airlines logo]()
$895
This Air Canada deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:30 am -
2 stops19h 20m
Mon 12/79:55 pm -
1 stop25h 17m
Deal found 10/20![Air Canada logo]()
$910
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:09 am -
2 stops14h 32m
Sat 11/2112:55 am -
2 stops12h 05m
Deal found 10/20![American Airlines logo]()
$848
This Expedia deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/99:30 am -
1 stop24h 35m
Mon 3/1510:35 am -
2 stops35h 35m
Deal found 10/19![Multiple Airlines logo]()
$948
This LATAM Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2512:05 pm -
1 stop18h 50m
Fri 2/512:05 am -
1 stop11h 36m
Deal found 10/21![LATAM Airlines logo]()
$968
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:10 am -
1 stop16h 00m
Wed 11/2510:40 am -
2 stops23h 20m
Deal found 10/21![United Airlines logo]()
$753
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/228:20 am -
2 stops11h 32m
Sun 5/212:59 am -
1 stop20h 46m
Deal found 10/20![Delta logo]()
$834
This Copa Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/237:45 pm -
2 stops23h 20m
Sat 4/38:55 am -
2 stops23h 40m
Deal found 10/22![Copa Airlines logo]()
$944
This Air Canada deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/29:30 am -
1 stop23h 05m
Thu 3/49:30 pm -
1 stop25h 40m
Deal found 10/19![Air Canada logo]()
$945
This Air Canada deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/239:30 am -
2 stops41h 45m
Sat 4/35:35 pm -
2 stops26h 37m
Deal found 10/23![Multiple Airlines logo]()
$1,026
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:05 am -
1 stop14h 20m
Thu 12/108:55 am -
2 stops15h 38m
Deal found 10/19![Delta logo]()
$848
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2711:43 am -
1 stop10h 27m
Sun 1/3110:40 am -
1 stop13h 04m
Deal found 10/19![United Airlines logo]()
$784
This CheapOair deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/59:30 am -
2 stops43h 20m
Mon 3/89:55 pm -
1 stop25h 15m
Deal found 10/19![Air Canada logo]()
$974
This Copa Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:03 pm -
2 stops26h 42m
Wed 3/3110:25 am -
2 stops22h 10m
Deal found 10/20![Copa Airlines logo]()
$1,016
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:05 am -
1 stop14h 20m
Tue 12/158:55 am -
2 stops15h 38m
Deal found 10/23![Delta logo]()
$848
Last-minute flights from Columbus to South AmericaDiscover last-minute flight deals from Columbus to South America. Data last updated October 24, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to South America. Data last updated October 24, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:59 pm -
2 stops18h 11m
Tue 10/277:35 pm -
2 stops13h 20m
Deal found 10/20![Avianca logo]()
$745
This Avianca deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:10 am -
2 stops18h 10m
Tue 11/36:00 pm -
2 stops15h 55m
Deal found 10/22![Avianca logo]()
$751
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:13 pm -
1 stop9h 17m
Mon 11/23:15 pm -
1 stop8h 44m
Deal found 10/20![American Airlines logo]()
$638
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:56 pm -
2 stops30h 09m
Mon 11/28:15 am -
2 stops28h 55m
Deal found 10/20![United Airlines logo]()
$642
This deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:38 am -
1 stop11h 27m
Tue 11/171:30 am -
1 stop9h 22m
Deal found 10/20![United Airlines logo]()
$623
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:00 am -
2 stops16h 05m
Mon 11/161:30 am -
2 stops15h 19m
Deal found 10/23![United Airlines logo]()
$627
This LATAM Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:05 am -
1 stop12h 25m
Thu 1/149:00 am -
2 stops15h 10m
Deal found 10/20![LATAM Airlines logo]()
$626
This Air Canada deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:30 am -
2 stops41h 45m
Wed 11/252:55 am -
2 stops18h 17m
Deal found 10/19![Multiple Airlines logo]()
$728
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:49 pm -
2 stops26h 21m
Wed 12/210:40 am -
1 stop13h 04m
Deal found 10/19![United Airlines logo]()
$753
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:15 am -
1 stop15h 55m
Wed 12/210:40 am -
1 stop13h 04m
Deal found 10/19![United Airlines logo]()
$749
This LATAM Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:05 am -
2 stops15h 45m
Wed 12/27:10 am -
2 stops17h 23m
Deal found 10/19![LATAM Airlines logo]()
$762
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:13 pm -
2 stops19h 21m
Fri 12/42:36 pm -
1 stop9h 22m
Deal found 10/22![American Airlines logo]()
$535
One-way flights from Columbus to South AmericaSearch for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
Search for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
This Orbitz deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/308:48 pm -
1 stop14h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Frontier logo]()
$223
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:20 pm -
2 stops17h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$238
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:39 pm -
1 stop20h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:44 pm -
3 stops36h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$254
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:13 pm -
2 stops17h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![American Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:44 pm -
3 stops27h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:28 am -
1 stop9h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:28 am -
2 stops18h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$303
This LATAM Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
1 stop7h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![LATAM Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:13 pm -
3 stops20h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$317
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:15 am -
2 stops16h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:28 am -
2 stops31h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$321
Find flight deals from Columbus to South America
Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated October 24, 2026.
Round-trip from | $531 (United Airlines) |
|---|---|
One-way from | $223 (Orbitz) |
Popular in | August |
Cheapest in | April |
Average price | $1,628 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Fri 11/13
5:39 pm-2:19 pm
1 stop20h 40m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$252
ColumbusMedellín
CMH Columbus - MDE Medellín Jose Maria Cordova Intl
CMHMDE
Columbus
Thu 11/12
7:44 pm-8:15 am
3 stops36h 31m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$254
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Fri 11/27
8:13 pm-1:32 pm
2 stops17h 19m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$254
Quickest round-trip
ColumbusBogotá
CMH Columbus - BOG Bogotá El Dorado
CMHBOG
Columbus
Fri 11/27
10:28 am-8:05 pm
1 stop9h 37m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$297
ColumbusMedellín
CMH Columbus - MDE Medellín Jose Maria Cordova Intl
CMHMDE
Columbus
Wed 11/11
6:13 pm-2:45 pm
3 stops20h 32m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$317
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Fri 11/13
6:15 am-11:00 pm
2 stops16h 45m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$320
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Fri 11/27
5:39 pm-2:09 pm
1 stop20h 30m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$324
ColumbusLima
CMH Columbus - LIM Lima J Chavez Intl
CMHLIM
Columbus
Wed 12/2
1:32 pm-3:40 pm
3 stops50h 08m
Lima J Chavez Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$326
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Wed 11/11
4:58 pm-11:00 pm
2 stops30h 02m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$337
ColumbusBogotá
CMH Columbus - BOG Bogotá El Dorado
CMHBOG
Columbus
Wed 11/4
6:00 am-9:55 am
2 stops27h 55m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$346
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Columbus to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
CMH-CTG
CMH-BOG
CMH-LIM
CMH-MDE
CMH-UIO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to South America
CMH-0SA
CMH-CTG
CMH-BOG
CMH-LIM
CMH-MDE
What is the cheapest month to book a flight from Columbus Airport to South America?
Currently, March is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $669). Flying from Columbus Airport to South America in December is currently the most expensive (average of $1,094). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated October 24, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from Columbus Airport to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Overall
7.8
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Boarding
8.1
Overall
7.8
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Boarding
8.1
Overall
7.8
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Boarding
8.1
Overall
7.8
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Boarding
8.1
Overall
7.8
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Boarding
8.1
Overall
7.8
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Columbus to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbus to South America by cabin class
Find flights from Columbus to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and South America flights
Browse other Columbus and South America flight options. Last updated on October 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Columbus to South America flights
Consider these flights traveling from Columbus to South America.
Top 4 airlines flying from Columbus to South America
Discover the top 4 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$491 | Average$825 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$563 | Average$1,136 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$580 | Average$930 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$614 | Average$907 | FlexibilityNo cancel fee | On-time81% |