$154+ Cheap flights from Columbus (CMH) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
May 12 — May 191
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to South America with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Columbus to South AmericaExplore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
CMH
- MDE
1 stop7h 43m
Spirit Airlines
Sat 5/161:55 pm
MDE
- CMH
1 stop21h 47m
Spirit Airlines
Deal found 4/9![Spirit Airlines logo]()
$404
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:37 pm
CMH
- MDE
1 stop24h 23m
Multiple Airlines
Mon 5/114:45 pm
MDE
- CMH
2 stops47h 50m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$436
This CheapOair deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:37 pm
CMH
- MDE
1 stop24h 23m
Spirit Airlines
Fri 5/292:06 pm
MDE
- CMH
1 stop8h 50m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$441
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:37 pm
CMH
- MDE
1 stop24h 23m
Spirit Airlines
Thu 5/282:06 pm
MDE
- CMH
1 stop8h 50m
Spirit Airlines
Deal found 4/9![Spirit Airlines logo]()
$446
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:58 pm
CMH
- MDE
1 stop17h 06m
Multiple Airlines
Wed 7/12:00 pm
MDE
- CMH
2 stops26h 05m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$465
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:37 pm
CMH
- MDE
1 stop24h 23m
Spirit Airlines
Mon 5/111:55 pm
MDE
- CMH
1 stop21h 47m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$501
This Mytrip deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:30 pm
CMH
- GYE
3 stops27h 34m
Multiple Airlines
Mon 5/113:30 am
GYE
- CMH
3 stops32h 12m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$620
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
CMH
- GYE
1 stop18h 04m
Multiple Airlines
Mon 5/46:45 pm
GYE
- CMH
2 stops21h 25m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$641
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:00 am
CMH
- GYE
1 stop16h 37m
American Airlines
Thu 7/302:37 pm
GYE
- CMH
1 stop21h 20m
American Airlines
Deal found 4/7![American Airlines logo]()
$664
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 am
CMH
- GYE
2 stops17h 37m
American Airlines
Tue 7/216:00 am
GYE
- CMH
2 stops14h 56m
American Airlines
Deal found 4/7![American Airlines logo]()
$669
This Cheapflightsfares deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:20 am
CMH
- LIM
1 stop18h 38m
Spirit Airlines
Sat 10/311:30 am
LIM
- CMH
1 stop11h 25m
Spirit Airlines
Deal found 4/10![Spirit Airlines logo]()
$670
This Travelocity deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:20 am
CMH
- LIM
1 stop18h 38m
Spirit Airlines
Sat 11/1412:30 pm
LIM
- CMH
1 stop11h 25m
Spirit Airlines
Deal found 4/9![Spirit Airlines logo]()
$671
Best flights from Columbus to South AmericaDiscover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 12, 2026.
Discover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:37 pm
CMH
- MDE
1 stop24h 23m
Multiple Airlines
Mon 5/114:45 pm
MDE
- CMH
2 stops47h 50m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$436
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:37 pm
CMH
- MDE
1 stop24h 23m
Spirit Airlines
Fri 5/292:06 pm
MDE
- CMH
1 stop8h 50m
Spirit Airlines
Deal found 4/9![Spirit Airlines logo]()
$441
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:00 am
CMH
- GYE
1 stop16h 37m
American Airlines
Thu 7/302:37 pm
GYE
- CMH
1 stop21h 20m
American Airlines
Deal found 4/7![American Airlines logo]()
$664
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:37 am
CMH
- GEO
1 stop11h 58m
United Airlines
Mon 6/112:40 am
GEO
- CMH
1 stop15h 22m
United Airlines
Deal found 4/11![United Airlines logo]()
$683
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:29 pm
CMH
- GYE
1 stop13h 31m
Delta
Tue 7/214:05 pm
GYE
- CMH
1 stop18h 43m
Delta
Deal found 4/7![Delta logo]()
$684
This FlightHub deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:00 am
CMH
- LIM
1 stop15h 55m
LATAM Airlines
Tue 10/2712:00 pm
LIM
- CMH
1 stop10h 55m
LATAM Airlines
Deal found 4/8![LATAM Airlines logo]()
$699
This Copa Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:10 am
CMH
- LIM
2 stops17h 10m
Copa Airlines
Tue 10/204:40 pm
LIM
- CMH
2 stops15h 55m
Copa Airlines
Deal found 4/7![Copa Airlines logo]()
$732
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:37 pm
CMH
- MDE
1 stop24h 23m
Spirit Airlines
Thu 5/282:06 pm
MDE
- CMH
1 stop8h 50m
Spirit Airlines
Deal found 4/9![Spirit Airlines logo]()
$446
This Expedia deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:00 am
CMH
- MDE
1 stop7h 43m
Spirit Airlines
Sun 5/242:06 pm
MDE
- CMH
1 stop8h 50m
Spirit Airlines
Deal found 4/6![Spirit Airlines logo]()
$449
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:28 pm
CMH
- MDE
2 stops19h 32m
Multiple Airlines
Sun 5/241:55 pm
MDE
- CMH
1 stop21h 47m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$497
This Mytrip deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:00 am
CMH
- MDE
3 stops24h 56m
Multiple Airlines
Fri 5/296:20 am
MDE
- CMH
3 stops16h 36m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$530
This Booking.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:55 am
CMH
- SDU
2 stops44h 45m
Air Canada
Wed 5/131:45 pm
SDU
- CMH
2 stops26h 37m
Air Canada
Deal found 4/8![Air Canada logo]()
$1,244
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:37 pm
CMH
- MDE
1 stop24h 23m
Spirit Airlines
Sun 5/101:55 pm
MDE
- CMH
1 stop21h 47m
Spirit Airlines
Deal found 4/6![Spirit Airlines logo]()
$524
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:30 am
CMH
- UIO
1 stop23h 30m
United Airlines
Mon 8/247:25 am
UIO
- CMH
2 stops24h 10m
United Airlines
Deal found 4/7![United Airlines logo]()
$687
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 am
CMH
- GYE
2 stops17h 37m
American Airlines
Tue 7/212:37 pm
GYE
- CMH
2 stops17h 27m
American Airlines
Deal found 4/8![American Airlines logo]()
$689
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:55 pm
CMH
- UIO
1 stop24h 04m
Delta
Sun 9/66:50 pm
UIO
- CMH
2 stops18h 40m
Delta
Deal found 4/7![Delta logo]()
$726
This Copa Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/289:00 am
CMH
- LIM
2 stops17h 20m
Copa Airlines
Tue 9/811:00 am
LIM
- CMH
2 stops20h 35m
Copa Airlines
Deal found 4/7![Copa Airlines logo]()
$732
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:01 pm
CMH
- UIO
1 stop12h 59m
United Airlines
Mon 8/247:25 am
UIO
- CMH
1 stop15h 17m
United Airlines
Deal found 4/8![United Airlines logo]()
$687
This Mytrip deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
CMH
- GYE
1 stop18h 04m
Multiple Airlines
Mon 5/113:30 am
GYE
- CMH
3 stops32h 12m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$656
This Delta deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:08 pm
CMH
- UIO
1 stop23h 51m
Delta
Tue 6/236:50 pm
UIO
- CMH
2 stops16h 01m
Delta
Deal found 4/11![Delta logo]()
$728
This Copa Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/911:03 am
CMH
- LIM
2 stops15h 17m
Copa Airlines
Mon 7/204:40 pm
LIM
- CMH
2 stops16h 17m
Copa Airlines
Deal found 4/8![Copa Airlines logo]()
$732
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:55 pm
CMH
- GEO
2 stops26h 40m
United Airlines
Thu 5/2812:40 am
GEO
- CMH
1 stop15h 22m
United Airlines
Deal found 4/7![United Airlines logo]()
$707
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
CMH
- LIM
2 stops16h 35m
Delta
Wed 8/1912:10 am
LIM
- CMH
2 stops20h 10m
Delta
Deal found 4/9![Delta logo]()
$729
This Copa Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:03 am
CMH
- LIM
2 stops15h 17m
Copa Airlines
Wed 7/291:20 pm
LIM
- CMH
2 stops19h 37m
Copa Airlines
Deal found 4/8![Copa Airlines logo]()
$732
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
CMH
- LIM
2 stops16h 35m
Delta
Tue 8/1812:15 am
LIM
- CMH
2 stops17h 34m
Delta
Deal found 4/9![Delta logo]()
$734
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:55 pm
CMH
- LIM
2 stops27h 05m
United Airlines
Mon 10/1912:55 am
LIM
- CMH
1 stop13h 55m
United Airlines
Deal found 4/9![United Airlines logo]()
$734
This KAYAK deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:50 pm
CMH
- CUZ
2 stops27h 30m
LATAM Airlines
Tue 9/158:25 am
CUZ
- CMH
2 stops23h 33m
LATAM Airlines
Deal found 4/7![LATAM Airlines logo]()
$1,021
This Mytrip deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:00 am
CMH
- LIM
3 stops20h 45m
Multiple Airlines
Sun 5/172:50 am
LIM
- CMH
3 stops32h 52m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$780
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:00 pm
CMH
- UIO
2 stops30h 25m
United Airlines
Sat 8/227:25 am
UIO
- CMH
2 stops13h 57m
United Airlines
Deal found 4/8![United Airlines logo]()
$758
This KAYAK deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:30 pm
CMH
- CUZ
2 stops28h 20m
LATAM Airlines
Tue 9/158:35 am
CUZ
- CMH
2 stops14h 24m
LATAM Airlines
Deal found 4/8![LATAM Airlines logo]()
$1,021
Last-minute flights from Columbus to South AmericaDiscover last-minute flight deals from Columbus to South America. Data last updated April 12, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to South America. Data last updated April 12, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:30 pm
CMH
- GYE
3 stops27h 34m
Multiple Airlines
Mon 5/113:30 am
GYE
- CMH
3 stops32h 12m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$620
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
CMH
- GYE
1 stop18h 04m
Multiple Airlines
Mon 5/46:45 pm
GYE
- CMH
2 stops21h 25m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$641
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:37 pm
CMH
- MDE
1 stop24h 23m
Multiple Airlines
Mon 5/114:45 pm
MDE
- CMH
2 stops47h 50m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$436
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:37 pm
CMH
- MDE
1 stop24h 23m
Spirit Airlines
Mon 5/111:55 pm
MDE
- CMH
1 stop21h 47m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$501
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
CMH
- MDE
1 stop7h 43m
Spirit Airlines
Sat 5/161:55 pm
MDE
- CMH
1 stop21h 47m
Spirit Airlines
Deal found 4/9![Spirit Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:37 am
CMH
- GEO
1 stop11h 58m
United Airlines
Mon 6/112:40 am
GEO
- CMH
1 stop15h 22m
United Airlines
Deal found 4/11![United Airlines logo]()
$683
This CheapOair deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:37 pm
CMH
- MDE
1 stop24h 23m
Spirit Airlines
Fri 5/292:06 pm
MDE
- CMH
1 stop8h 50m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$441
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:37 pm
CMH
- MDE
1 stop24h 23m
Spirit Airlines
Thu 5/282:06 pm
MDE
- CMH
1 stop8h 50m
Spirit Airlines
Deal found 4/9![Spirit Airlines logo]()
$446
This Mytrip deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:00 am
CMH
- MDE
2 stops18h 30m
Multiple Airlines
Fri 5/295:00 am
MDE
- CMH
2 stops17h 56m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$507
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:55 pm
CMH
- GEO
2 stops26h 40m
United Airlines
Thu 5/2812:40 am
GEO
- CMH
2 stops14h 48m
United Airlines
Deal found 4/7![United Airlines logo]()
$707
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:08 am
CMH
- UIO
1 stop16h 49m
American Airlines
Thu 6/46:00 am
UIO
- CMH
1 stop17h 45m
American Airlines
Deal found 4/7![American Airlines logo]()
$704
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:00 am
CMH
- GYE
1 stop16h 37m
American Airlines
Mon 6/16:00 am
GYE
- CMH
1 stop17h 45m
American Airlines
Deal found 4/10![American Airlines logo]()
$713
One-way flights from Columbus to South AmericaSearch for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated April 12, 2026.
Search for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated April 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:28 pm
CMH
- MDE
2 stops19h 32m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:05 pm
CMH
- GYE
3 stops39h 50m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:00 am
CMH
- MDE
1 stop7h 43m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:48 pm
CMH
- LIM
3 stops53h 12m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$357
This Ovago deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1012:48 pm
CMH
- LIM
1 stop10h 07m
LATAM Airlines
Deal found 4/11![LATAM Airlines logo]()
$433
This Copa Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3011:03 am
CMH
- LIM
2 stops15h 17m
Copa Airlines
Deal found 4/7![Copa Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:00 am
CMH
- GYE
1 stop16h 37m
American Airlines
Deal found 4/10![American Airlines logo]()
$443
This Ovago deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3012:00 pm
CMH
- LIM
1 stop10h 55m
LATAM Airlines
Deal found 4/8![LATAM Airlines logo]()
$460
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:13 pm
CMH
- LIM
1 stop10h 57m
American Airlines
Deal found 4/7![American Airlines logo]()
$467
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:07 pm
CMH
- EZE
3 stops38h 09m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$570
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:07 pm
CMH
- AEP
3 stops37h 23m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$594
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:11 pm
CMH
- CUZ
2 stops22h 59m
American Airlines
Deal found 4/8![American Airlines logo]()
$600
Find flight deals from Columbus to South America
Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated April 12, 2026.
Round-trip from | $404 (CheapOair) |
|---|---|
One-way from | $154 (Kiwi.com) |
Popular in | February |
Cheapest in | October |
Average price | $388 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Mon 5/4
1:37 pm-1:00 pm
1 stop24h 23m
Medellín Jose Maria Cordova Intl
Mon 5/11
4:45 pm-5:35 pm
2 stops47h 50m
$436
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Fri 5/22
1:37 pm-1:00 pm
1 stop24h 23m
Medellín Jose Maria Cordova Intl
Fri 5/29
2:06 pm-11:56 pm
1 stop8h 50m
$441
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Fri 5/22
1:37 pm-1:00 pm
1 stop24h 23m
Medellín Jose Maria Cordova Intl
Thu 5/28
2:06 pm-11:56 pm
1 stop8h 50m
$446
Quickest round-trip
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Fri 5/22
6:00 am-12:43 pm
1 stop7h 43m
Medellín Jose Maria Cordova Intl
Sun 5/24
2:06 pm-11:56 pm
1 stop8h 50m
$449
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Fri 5/22
6:28 pm-1:00 pm
2 stops19h 32m
Medellín Jose Maria Cordova Intl
Sun 5/24
1:55 pm-12:42 pm
1 stop21h 47m
$497
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Thu 5/7
1:37 pm-1:00 pm
1 stop24h 23m
Medellín Jose Maria Cordova Intl
Sun 5/10
1:55 pm-12:42 pm
1 stop21h 47m
$524
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Fri 5/22
6:00 am-5:56 am
3 stops24h 56m
Medellín Jose Maria Cordova Intl
Fri 5/29
6:20 am-11:56 pm
3 stops16h 36m
$530
ColumbusGuayaquil
CMH - GYE
CMHGYE
Columbus
Sat 4/25
6:00 am-11:04 pm
1 stop18h 04m
Guayaquil Jose Joaquin de Olmedo
Mon 5/11
3:30 am-12:42 pm
3 stops32h 12m
$656
ColumbusGuayaquil
CMH - GYE
CMHGYE
Columbus
Tue 6/9
7:00 am-10:37 pm
1 stop16h 37m
Guayaquil Jose Joaquin de Olmedo
Thu 7/30
2:37 pm-12:57 pm
1 stop21h 20m
$664
ColumbusGeorgetown
CMH - GEO
CMHGEO
Columbus
Tue 5/12
11:37 am-11:35 pm
1 stop11h 58m
Georgetown Cheddi Jagan Intl
Mon 6/1
12:40 am-4:02 pm
1 stop15h 22m
$683
Showing 1-10 of 47 resultsSorted by cheapest first
Best time to book a flight from Columbus to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
CMH-MDE
CMH-GYE
CMH-GEO
CMH-UIO
CMH-LIM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to South America
CMH-0SA
CMH-MDE
CMH-GYE
CMH-GEO
CMH-UIO
What is the cheapest month to book a flight from Columbus Airport to South America?
Currently, February is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $243). Flying from Columbus Airport to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 12, 2026.
Get a feel of what it's like to fly with Delta,LATAM Airlines, andUnited Airlines from Columbus Airport to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.9
Food
7.2
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Food
7.2
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Food
7.2
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Food
7.2
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Food
7.2
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Food
7.2
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Columbus to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbus to South America by cabin class
Find flights from Columbus to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and South America flights
Browse other Columbus and South America flight options. Last updated on April 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Columbus to South America flights
Consider these flights traveling from Columbus to South America.
Top 5 airlines flying from Columbus to South America
Discover the top 5 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$244 | Average$409 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$552 | Average$795 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$552 | Average$767 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$658 | Average$948 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$962 | Average$1,449 | FlexibilityNo cancel fee | On-time69% |