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South America

$115+ Cheap flights from Columbus (CMH) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Mar 13 — Mar 201
Fri 3/13
Fri 3/20
1 adult, Economy
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Cheap flight deals from Columbus to South America

Cheapest flights from Columbus to South America
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:15 am
CMH
-
MDE
1 stop7h 58m
Spirit Airlines
Mon 3/161:17 am
MDE
-
CMH
1 stop7h 24m
Spirit Airlines
Deal found 2/8$264
This Priceline deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:15 am
CMH
-
MDE
1 stop7h 58m
Spirit Airlines
Mon 3/161:17 am
MDE
-
CMH
1 stop7h 24m
Spirit Airlines
Deal found 2/9$266
This Cheapflightsfares deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:45 am
CMH
-
MDE
1 stop8h 37m
Spirit Airlines
Tue 4/142:17 pm
MDE
-
CMH
1 stop7h 32m
Spirit Airlines
Deal found 2/8$271
This CheapOair deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:15 am
CMH
-
MDE
1 stop7h 58m
Spirit Airlines
Wed 3/181:17 am
MDE
-
CMH
1 stop7h 24m
Spirit Airlines
Deal found 2/9$281
This CheapOair deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:15 am
CMH
-
MDE
1 stop7h 58m
Spirit Airlines
Thu 3/122:17 pm
MDE
-
CMH
1 stop7h 32m
Spirit Airlines
Deal found 2/8$286
This Cheapflightsfares deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:45 am
CMH
-
MDE
1 stop8h 10m
Spirit Airlines
Wed 3/112:15 pm
MDE
-
CMH
1 stop8h 17m
Spirit Airlines
Deal found 2/9$289
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:25 am
CMH
-
MDE
1 stop19h 17m
Multiple Airlines
Sun 4/261:37 am
MDE
-
CMH
2 stops12h 04m
Multiple Airlines
Deal found 2/9$300
This CheapOair deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:25 am
CMH
-
MDE
1 stop19h 17m
Spirit Airlines
Mon 4/201:37 am
MDE
-
CMH
1 stop19h 36m
Spirit Airlines
Deal found 2/9$304
This Orbitz deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:15 am
CMH
-
CTG
1 stop6h 55m
Spirit Airlines
Sat 3/72:21 pm
CTG
-
CMH
1 stop9h 11m
Spirit Airlines
Deal found 2/11$326
This CheapOair deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:15 am
CMH
-
CTG
1 stop6h 55m
Spirit Airlines
Mon 3/161:14 pm
CTG
-
CMH
1 stop19h 27m
Spirit Airlines
Deal found 2/8$339
This FlightHub deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
CMH
-
GYE
1 stop18h 04m
Spirit Airlines
Fri 5/2211:59 pm
GYE
-
CMH
1 stop13h 46m
Spirit Airlines
Deal found 2/11$344
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:40 am
CMH
-
GYE
1 stop13h 24m
Multiple Airlines
Tue 4/1411:59 pm
GYE
-
CMH
2 stops37h 42m
Multiple Airlines
Deal found 2/10$347

Find flight deals from Columbus to South America

Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated February 11, 2026.

Round-trip from

$264
(Cheapflightsfares)

One-way from

$115
(Cheapflightsfares)

Popular in

December

Cheapest in

October

Average price

$811
From Columbus to South America
Search Deals
One-way flight from Columbus to South America
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($114 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.

Fly from

Columbus

Fly to

South America

Route

Depart

Return

Price

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 3/11

6:15 am-1:13 pm

1 stop7h 58m

Medellín Jose Maria Cordova Intl

Mon 3/16

1:17 am-9:41 am

1 stop7h 24m

$266

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Thu 4/9

5:45 am-1:22 pm

1 stop8h 37m

Medellín Jose Maria Cordova Intl

Mon 4/13

1:17 am-9:41 am

1 stop7h 24m

$271

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 3/10

6:15 am-1:13 pm

1 stop7h 58m

Medellín Jose Maria Cordova Intl

Wed 3/18

1:17 am-9:41 am

1 stop7h 24m

$281

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 3/10

6:15 am-1:13 pm

1 stop7h 58m

Medellín Jose Maria Cordova Intl

Tue 3/17

1:52 pm-9:41 am

2 stops18h 49m

$296

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 4/22

6:25 am-12:42 am

1 stop19h 17m

Medellín Jose Maria Cordova Intl

Sun 4/26

1:37 am-2:41 pm

2 stops12h 04m

$300

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 4/15

6:25 am-12:42 am

1 stop19h 17m

Medellín Jose Maria Cordova Intl

Mon 4/20

1:37 am-10:13 pm

1 stop19h 36m

$304

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Mon 3/2

6:15 am-2:13 pm

1 stop7h 58m

Medellín Jose Maria Cordova Intl

Thu 3/12

10:49 am-9:41 am

2 stops21h 52m

$305

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 3/10

6:15 am-1:13 pm

1 stop7h 58m

Medellín Jose Maria Cordova Intl

Tue 3/17

1:17 am-10:49 pm

1 stop20h 32m

$318

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 3/10

6:15 am-7:45 pm

2 stops14h 30m

Medellín Jose Maria Cordova Intl

Tue 3/17

6:05 am-9:41 am

2 stops26h 36m

$331

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

Tue 5/12

6:00 am-11:04 pm

1 stop18h 04m

Guayaquil Jose Joaquin de Olmedo

Fri 5/22

11:59 pm-2:45 pm

1 stop13h 46m

$344

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Showing 1-10 of 58 results
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Best time to book a flight from Columbus to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to South America

What is the cheapest month to book a flight from Columbus Airport to South America?

Currently, February is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $244). Flying from Columbus Airport to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 11, 2026.
Get a feel of what it's like to fly with Delta, LATAM Airlines, and American Airlines from Columbus Airport to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,179 reviews

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,179 reviews
Delta
7.9
Good
8,179 reviews

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,921 reviews
Delta
7.9
Good
8,179 reviews

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,267 reviews
Delta
7.9
Good
8,179 reviews

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Air Canada
7.1
Good
10,709 reviews
Delta
7.9
Good
8,179 reviews

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,444 reviews
Delta
7.9
Good
8,179 reviews

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus Airport to South America?

    Spirit Airlines and United Airlines can get you from Columbus Airport to South America in just under 7h 58m. Your travel time can differ by up to 10h 12m. Airlines will cover a distance of 2382 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Columbus Airport to South America?

    When deciding which route to take from Columbus Airport to South America consider Columbus - Rio de Janeiro Santos Dumont, Columbus - Rio de Janeiro–Galeão Intl or Columbus - Lima J Chavez Intl as they are the most popular.

  • Can I find deals for flights from Columbus to South America that include hotel bookings?

    Yes. In addition to deals on Columbus to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to South America.

  • Can I find deals for business class flights from Columbus to South America?

    Yes. Cheapflights offers flight deals from Columbus to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to South America?

    Currently, February is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $244). Flying from Columbus Airport to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Columbus to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Columbus to South America

Discover the top 5 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$244Average$375FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$443Average$745FlexibilityNo cancel feeOn-time71%
DeltaCheapest$552Average$872FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$562Average$803FlexibilityNo cancel feeOn-time81%
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

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