$218+ Cheap flights from Columbus (CMH) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Oct 26 — Nov 21
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Columbus to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to South America
Cheapest
Best
Last-minute
One-way
Cheapest flights from Columbus to South AmericaExplore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 26, 2026.
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 26, 2026.
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:20 pm -
2 stops19h 16m
Thu 11/122:35 pm -
1 stop9h 24m
Deal found 9/21![American Airlines logo]()
$475
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:29 am -
1 stop7h 07m
Mon 11/164:37 pm -
2 stops19h 13m
Deal found 9/25![American Airlines logo]()
$520
This BusinessClass deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:03 pm -
2 stops21h 33m
Thu 12/102:35 pm -
2 stops17h 59m
Deal found 9/24![GOL logo]()
$571
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:42 pm -
2 stops20h 53m
Mon 10/121:35 pm -
2 stops19h 47m
Deal found 9/22![American Airlines logo]()
$625
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:30 am -
2 stops17h 30m
Mon 10/263:05 pm -
2 stops42h 47m
Deal found 9/22![United Airlines logo]()
$658
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:00 am -
1 stop8h 19m
Mon 11/163:34 pm -
1 stop8h 56m
Deal found 9/25![Delta logo]()
$675
This Mytrip deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:17 am -
2 stops19h 33m
Mon 10/264:20 pm -
2 stops25h 32m
Deal found 9/21![Multiple Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:05 am -
2 stops14h 29m
Thu 11/127:30 am -
2 stops14h 14m
Deal found 9/21![American Airlines logo]()
$693
This Mytrip deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:17 am -
2 stops19h 53m
Mon 10/2612:05 pm -
3 stops29h 47m
Deal found 9/22![Multiple Airlines logo]()
$712
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:30 am -
2 stops11h 50m
Fri 11/137:30 am -
1 stop13h 59m
Deal found 9/22![American Airlines logo]()
$713
This Justfly.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:10 am -
1 stop14h 00m
Fri 11/2010:50 pm -
1 stop15h 27m
Deal found 9/23![Avianca logo]()
$719
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:30 am -
1 stop15h 40m
Wed 10/289:45 am -
1 stop13h 11m
Deal found 9/25![United Airlines logo]()
$728
Best flights from Columbus to South AmericaDiscover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 26, 2026.
Discover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 26, 2026.
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/67:45 pm -
1 stop17h 25m
Sun 2/142:20 pm -
1 stop9h 22m
Deal found 9/25![United Airlines logo]()
$490
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/216:42 pm -
2 stops20h 56m
Mon 2/12:35 pm -
2 stops20h 08m
Deal found 9/22![American Airlines logo]()
$500
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/117:55 pm -
1 stop18h 20m
Thu 3/182:30 pm -
1 stop8h 40m
Deal found 9/21![Delta logo]()
$533
This Mytrip deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:17 am -
2 stops19h 33m
Mon 10/264:20 pm -
2 stops25h 32m
Deal found 9/21![Multiple Airlines logo]()
$691
This Justfly.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:10 am -
1 stop14h 00m
Fri 11/2010:50 pm -
1 stop15h 27m
Deal found 9/23![Avianca logo]()
$719
This Air Canada deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:30 am -
2 stops19h 20m
Mon 12/79:55 pm -
1 stop25h 17m
Deal found 9/24![Air Canada logo]()
$900
This FlightHub deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:05 am -
2 stops14h 00m
Sun 11/2912:05 am -
1 stop11h 44m
Deal found 9/22![LATAM Airlines logo]()
$987
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:04 am -
2 stops16h 16m
Mon 11/304:40 pm -
2 stops26h 17m
Deal found 9/22![Copa Airlines logo]()
$994
This Ovago deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:55 am -
1 stop22h 10m
Mon 10/269:30 pm -
1 stop24h 42m
Deal found 9/21![Azul logo]()
$1,283
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:30 am -
2 stops17h 30m
Mon 10/263:05 pm -
2 stops42h 47m
Deal found 9/22![United Airlines logo]()
$658
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2010:54 am -
1 stop10h 16m
Sat 2/277:00 am -
1 stop15h 54m
Deal found 9/22![American Airlines logo]()
$688
This GOL deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:29 am -
1 stop21h 06m
Sat 11/1412:05 am -
1 stop23h 24m
Deal found 9/23![GOL logo]()
$1,434
This Avianca deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2010:20 am -
1 stop9h 50m
Sat 2/2710:50 pm -
1 stop10h 45m
Deal found 9/24![Multiple Airlines logo]()
$720
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1110:05 am -
2 stops10h 05m
Mon 3/228:35 am -
2 stops14h 35m
Deal found 9/21![Delta logo]()
$721
This Avianca deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/207:45 pm -
3 stops17h 00m
Sat 2/277:35 pm -
2 stops14h 00m
Deal found 9/22![Avianca logo]()
$723
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/106:45 am -
1 stop15h 30m
Fri 3/199:45 am -
1 stop11h 05m
Deal found 9/21![United Airlines logo]()
$713
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/106:00 am -
1 stop13h 30m
Sun 3/213:55 pm -
1 stop18h 40m
Deal found 9/21![Delta logo]()
$726
This Avianca deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:49 pm -
1 stop9h 41m
Sun 11/1510:50 pm -
2 stops14h 20m
Deal found 9/24![Multiple Airlines logo]()
$769
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:00 am -
2 stops13h 15m
Sun 11/13:12 pm -
1 stop8h 47m
Deal found 9/24![American Airlines logo]()
$783
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1110:05 am -
2 stops10h 05m
Fri 3/193:55 pm -
1 stop18h 40m
Deal found 9/21![Delta logo]()
$731
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:15 am -
2 stops17h 00m
Thu 11/510:40 am -
2 stops23h 20m
Deal found 9/25![United Airlines logo]()
$758
This Air Canada deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:30 am -
2 stops25h 10m
Fri 11/208:00 am -
1 stop13h 12m
Deal found 9/21![Air Canada logo]()
$942
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:05 am -
2 stops13h 31m
Sat 11/2112:55 am -
2 stops11h 34m
Deal found 9/22![American Airlines logo]()
$808
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/126:00 am -
2 stops11h 55m
Sat 3/203:55 pm -
1 stop18h 40m
Deal found 9/21![Delta logo]()
$741
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:00 am -
1 stop17h 05m
Mon 11/168:15 am -
1 stop15h 29m
Deal found 9/25![United Airlines logo]()
$761
This LATAM Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:05 am -
2 stops13h 25m
Fri 11/2712:10 pm -
1 stop11h 30m
Deal found 9/25![LATAM Airlines logo]()
$1,037
This Copa Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:56 pm -
2 stops27h 49m
Fri 11/132:35 am -
2 stops17h 59m
Deal found 9/24![Copa Airlines logo]()
$1,066
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:30 am -
2 stops13h 05m
Tue 12/296:25 am -
1 stop15h 25m
Deal found 9/24![American Airlines logo]()
$828
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:05 am -
1 stop12h 10m
Mon 10/263:55 pm -
1 stop17h 15m
Deal found 9/21![Delta logo]()
$766
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:30 am -
1 stop13h 50m
Thu 10/298:15 am -
1 stop14h 29m
Deal found 9/22![United Airlines logo]()
$766
Last-minute flights from Columbus to South AmericaDiscover last-minute flight deals from Columbus to South America. Data last updated September 26, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to South America. Data last updated September 26, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:42 pm -
2 stops20h 53m
Mon 10/121:35 pm -
2 stops19h 47m
Deal found 9/22![American Airlines logo]()
$625
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:01 pm -
2 stops28h 09m
Wed 10/289:45 am -
1 stop13h 11m
Deal found 9/25![United Airlines logo]()
$748
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:30 am -
2 stops17h 30m
Mon 10/263:05 pm -
2 stops42h 47m
Deal found 9/22![United Airlines logo]()
$658
This Mytrip deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:17 am -
2 stops19h 33m
Mon 10/264:20 pm -
2 stops25h 32m
Deal found 9/21![Multiple Airlines logo]()
$691
This Mytrip deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:17 am -
2 stops19h 53m
Mon 10/2612:05 pm -
3 stops29h 47m
Deal found 9/22![Multiple Airlines logo]()
$712
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:50 pm -
2 stops26h 20m
Wed 10/289:45 am -
2 stops26h 25m
Deal found 9/25![United Airlines logo]()
$751
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:30 am -
1 stop15h 40m
Wed 10/289:45 am -
1 stop13h 11m
Deal found 9/25![United Airlines logo]()
$728
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/294:58 pm -
1 stop29h 17m
Tue 11/1010:40 am -
1 stop13h 04m
Deal found 9/25![United Airlines logo]()
$746
This Mytrip deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:44 pm -
3 stops24h 56m
Sun 11/11:19 pm -
3 stops26h 07m
Deal found 9/24![Multiple Airlines logo]()
$749
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/294:58 pm -
1 stop29h 17m
Thu 11/510:40 am -
2 stops26h 30m
Deal found 9/25![United Airlines logo]()
$750
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:15 am -
1 stop16h 00m
Wed 11/1110:40 am -
2 stops26h 30m
Deal found 9/25![United Airlines logo]()
$738
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:15 am -
1 stop16h 00m
Mon 11/910:40 am -
2 stops25h 02m
Deal found 9/25![United Airlines logo]()
$756
One-way flights from Columbus to South AmericaSearch for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated September 26, 2026.
Search for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated September 26, 2026.
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:40 am -
2 stops9h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![American Airlines logo]()
$218
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:08 am -
2 stops36h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Delta logo]()
$226
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:20 pm -
1 stop24h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Delta logo]()
$232
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:38 pm -
1 stop18h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![American Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/86:32 pm -
2 stops18h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:26 pm -
2 stops18h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:44 pm -
3 stops37h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:00 am -
2 stops16h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Delta logo]()
$280
This Priceline deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/88:41 pm -
1 stop16h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Frontier logo]()
$284
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:29 am -
1 stop7h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![American Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:44 pm -
3 stops27h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$298
This Mytrip deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:44 pm -
3 stops24h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$305
Find flight deals from Columbus to South America
Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated September 26, 2026.
Round-trip from | $470 (Delta) |
|---|---|
One-way from | $218 (American Airlines) |
Popular in | February |
Cheapest in | April |
Average price | $750 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 26, 2026.
Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Sun 11/1
6:26 am-3:36 pm
1 stop9h 10m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$218
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Sat 10/31
7:08 am-6:45 pm
2 stops36h 37m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$226
ColumbusBogotá
CMH Columbus - BOG Bogotá El Dorado
CMHBOG
Columbus
Mon 3/8
6:32 pm-1:05 pm
2 stops18h 33m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$238
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Wed 12/30
7:26 pm-2:01 pm
2 stops18h 35m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$248
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Mon 11/2
6:00 am-10:55 pm
2 stops16h 55m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$280
ColumbusMedellín
CMH Columbus - MDE Medellín Jose Maria Cordova Intl
CMHMDE
Columbus
Sun 10/18
7:44 pm-10:50 pm
2 stops28h 06m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$328
ColumbusLima
CMH Columbus - LIM Lima J Chavez Intl
CMHLIM
Columbus
Sun 10/18
7:44 pm-5:01 am
3 stops34h 17m
Lima J Chavez Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$334
ColumbusBogotá
CMH Columbus - BOG Bogotá El Dorado
CMHBOG
Columbus
Mon 12/7
6:32 pm-5:30 am
3 stops34h 58m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$347
ColumbusBogotá
CMH Columbus - BOG Bogotá El Dorado
CMHBOG
Columbus
Sun 12/13
12:43 pm-11:05 am
2 stops22h 22m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$364
ColumbusMedellín
CMH Columbus - MDE Medellín Jose Maria Cordova Intl
CMHMDE
Columbus
Tue 11/3
10:36 am-11:40 pm
2 stops13h 04m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$371
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Columbus to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
CMH-CTG
CMH-BOG
CMH-MDE
CMH-UIO
CMH-GRU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to South America
CMH-0SA
CMH-CTG
CMH-BOG
CMH-MDE
CMH-UIO
What is the cheapest month to book a flight from Columbus Airport to South America?
Currently, March is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $650). Flying from Columbus Airport to South America in December is currently the most expensive (average of $1,234). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 26, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from Columbus Airport to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top countries
Top destinations
Alternative routes for Columbus to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbus to South America by cabin class
Find flights from Columbus to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and South America flights
Browse other Columbus and South America flight options. Last updated on September 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Columbus to South America flights
Consider these flights traveling from Columbus to South America.
Top 4 airlines flying from Columbus to South America
Discover the top 4 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$491 | Average$887 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$563 | Average$1,153 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$575 | Average$883 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$614 | Average$898 | FlexibilityNo cancel fee | On-time81% |