$176+ Cheap flights from Columbus (CMH) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/30. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Dec 7 — Dec 141
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to South America
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Cheapest flights from Columbus to South AmericaExplore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 7, 2026.
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 7, 2026.
This JetBlue deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:10 am -
1 stop6h 35m
Mon 12/211:50 pm -
1 stop7h 50m
Deal found 11/6![JetBlue logo]()
$520
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:10 pm -
2 stops17h 26m
Sun 12/134:37 pm -
2 stops19h 07m
Deal found 11/1![American Airlines logo]()
$535
This JetBlue deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:05 am -
1 stop6h 40m
Fri 12/181:50 pm -
1 stop7h 50m
Deal found 11/6![JetBlue logo]()
$540
This JetBlue deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:10 am -
1 stop6h 35m
Mon 12/211:50 pm -
1 stop7h 50m
Deal found 11/6![JetBlue logo]()
$545
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:32 pm -
1 stop21h 28m
Sun 12/131:10 pm -
2 stops46h 48m
Deal found 11/4![Frontier logo]()
$571
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:59 am -
2 stops12h 06m
Sat 11/141:30 am -
1 stop9h 22m
Deal found 11/2![United Airlines logo]()
$638
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:10 am -
1 stop6h 35m
Sun 12/134:30 pm -
2 stops28h 42m
Deal found 11/4![Multiple Airlines logo]()
$731
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1512:53 pm -
2 stops23h 07m
Fri 12/251:10 pm -
1 stop24h 24m
Deal found 11/3![Frontier logo]()
$748
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/155:53 pm -
2 stops44h 57m
Tue 12/224:00 pm -
2 stops21h 16m
Deal found 11/6![United Airlines logo]()
$748
This Justfly.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1610:33 am -
1 stop25h 27m
Wed 1/271:10 pm -
1 stop20h 53m
Deal found 11/2![Frontier logo]()
$761
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:53 am -
2 stops13h 51m
Mon 12/218:00 am -
1 stop15h 26m
Deal found 11/6![American Airlines logo]()
$765
This BusinessClass deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:04 pm -
2 stops18h 30m
Tue 12/223:15 pm -
2 stops17h 35m
Deal found 11/5![GOL logo]()
$768
Best flights from Columbus to South AmericaDiscover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 7, 2026.
Discover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 7, 2026.
This JetBlue deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/206:00 am -
1 stop6h 44m
Fri 1/291:49 pm -
1 stop8h 04m
Deal found 11/6![JetBlue logo]()
$426
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:10 pm -
2 stops17h 26m
Sun 12/134:37 pm -
2 stops19h 07m
Deal found 11/1![American Airlines logo]()
$535
This Justfly.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/28:41 pm -
1 stop17h 24m
Tue 2/163:20 pm -
1 stop18h 43m
Deal found 11/6![Frontier logo]()
$535
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/246:15 am -
1 stop8h 35m
Tue 1/264:00 pm -
2 stops19h 33m
Deal found 11/6![United Airlines logo]()
$555
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/26:00 am -
1 stop13h 30m
Tue 2/166:35 pm -
2 stops15h 29m
Deal found 11/2![Delta logo]()
$623
This Air Canada deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/279:30 am -
2 stops41h 45m
Mon 3/12:55 am -
2 stops18h 15m
Deal found 11/6![Air Canada logo]()
$763
This JetBlue deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/226:00 am -
1 stop6h 44m
Tue 1/261:49 pm -
1 stop8h 04m
Deal found 11/6![JetBlue logo]()
$426
This Air Canada deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:30 am -
2 stops41h 45m
Mon 12/71:50 am -
2 stops19h 22m
Deal found 11/6![Multiple Airlines logo]()
$856
This LATAM Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/256:38 pm -
1 stop10h 22m
Mon 2/812:10 pm -
1 stop12h 19m
Deal found 11/6![LATAM Airlines logo]()
$993
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/215:40 am -
2 stops14h 35m
Fri 4/302:15 am -
2 stops15h 39m
Deal found 11/3![Copa Airlines logo]()
$1,032
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:43 pm -
2 stops19h 07m
Tue 1/264:00 pm -
2 stops18h 02m
Deal found 11/6![United Airlines logo]()
$555
This FlightHub deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/153:51 pm -
1 stop19h 14m
Sun 1/313:20 pm -
1 stop23h 36m
Deal found 11/2![Frontier logo]()
$562
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/186:00 am -
1 stop13h 30m
Mon 1/256:35 pm -
2 stops15h 28m
Deal found 11/6![Delta logo]()
$643
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/137:18 am -
1 stop8h 20m
Mon 1/252:35 pm -
2 stops20h 15m
Deal found 11/2![American Airlines logo]()
$645
This JetBlue deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/236:00 am -
1 stop6h 44m
Mon 2/11:49 pm -
1 stop8h 04m
Deal found 11/6![JetBlue logo]()
$600
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:59 am -
2 stops12h 06m
Sat 11/141:30 am -
1 stop9h 22m
Deal found 11/2![United Airlines logo]()
$638
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1610:33 am -
1 stop25h 27m
Wed 1/271:10 pm -
1 stop20h 53m
Deal found 11/4![Frontier logo]()
$761
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:12 am -
2 stops15h 23m
Sun 1/241:30 am -
2 stops20h 55m
Deal found 11/6![United Airlines logo]()
$712
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/46:00 am -
2 stops15h 30m
Sun 2/712:50 pm -
2 stops21h 13m
Deal found 11/1![Multiple Airlines logo]()
$878
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/316:00 am -
1 stop15h 33m
Tue 3/26:22 am -
1 stop18h 27m
Deal found 11/2![American Airlines logo]()
$844
This Air Canada deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:30 am -
2 stops19h 20m
Mon 12/79:55 pm -
1 stop25h 17m
Deal found 11/6![Air Canada logo]()
$940
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
2 stops12h 52m
Sun 11/2912:55 am -
1 stop15h 35m
Deal found 11/6![Delta logo]()
$868
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/157:45 pm -
2 stops43h 05m
Sat 12/192:20 pm -
1 stop9h 29m
Deal found 11/6![United Airlines logo]()
$748
This Super.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:05 am -
1 stop14h 15m
Sun 12/2011:40 pm -
1 stop17h 40m
Deal found 11/2![LATAM Airlines logo]()
$1,018
This Air Canada deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/239:30 am -
1 stop20h 40m
Sat 4/35:35 pm -
2 stops26h 37m
Deal found 11/6![Multiple Airlines logo]()
$939
This Copa Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/237:45 pm -
2 stops14h 25m
Sat 4/310:25 am -
2 stops22h 10m
Deal found 11/2![Copa Airlines logo]()
$1,048
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:05 am -
1 stop14h 20m
Thu 12/108:55 am -
2 stops15h 38m
Deal found 11/5![Delta logo]()
$868
This Air Canada deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/39:30 am -
2 stops27h 20m
Sun 3/79:00 pm -
1 stop26h 10m
Deal found 11/3![Air Canada logo]()
$999
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/187:12 am -
2 stops14h 58m
Mon 1/2510:40 am -
2 stops13h 19m
Deal found 11/6![United Airlines logo]()
$753
This Super.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:28 am -
1 stop9h 52m
Fri 12/1112:05 am -
1 stop17h 10m
Deal found 11/4![LATAM Airlines logo]()
$1,018
Last-minute flights from Columbus to South AmericaDiscover last-minute flight deals from Columbus to South America. Data last updated November 7, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to South America. Data last updated November 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:59 am -
2 stops12h 06m
Sat 11/141:30 am -
1 stop9h 22m
Deal found 11/2![United Airlines logo]()
$638
This BusinessClass deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:04 pm -
2 stops18h 30m
Tue 12/223:15 pm -
2 stops17h 35m
Deal found 11/5![GOL logo]()
$768
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:10 pm -
2 stops17h 26m
Sun 12/134:37 pm -
2 stops19h 07m
Deal found 11/1![American Airlines logo]()
$535
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:10 am -
1 stop6h 35m
Sun 12/134:30 pm -
2 stops28h 42m
Deal found 11/4![Multiple Airlines logo]()
$731
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:32 pm -
1 stop21h 28m
Sun 12/131:10 pm -
2 stops46h 48m
Deal found 11/4![Frontier logo]()
$571
This JetBlue deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:10 am -
1 stop6h 35m
Sat 12/191:50 pm -
1 stop7h 50m
Deal found 11/6![JetBlue logo]()
$520
This JetBlue deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:10 am -
1 stop6h 35m
Sun 12/201:50 pm -
1 stop7h 50m
Deal found 11/6![JetBlue logo]()
$545
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1512:53 pm -
2 stops23h 07m
Fri 12/251:10 pm -
1 stop24h 24m
Deal found 11/3![Frontier logo]()
$748
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/157:45 pm -
2 stops43h 05m
Sun 12/204:00 pm -
2 stops21h 16m
Deal found 11/6![United Airlines logo]()
$748
This JetBlue deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:05 am -
1 stop6h 40m
Fri 12/181:50 pm -
1 stop7h 50m
Deal found 11/6![JetBlue logo]()
$540
This Justfly.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1610:33 am -
1 stop25h 27m
Wed 1/271:10 pm -
1 stop20h 53m
Deal found 11/2![Frontier logo]()
$761
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:53 am -
2 stops13h 51m
Mon 12/218:00 am -
1 stop15h 26m
Deal found 11/6![American Airlines logo]()
$765
One-way flights from Columbus to South AmericaSearch for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated November 7, 2026.
Search for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated November 7, 2026.
This Priceline deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:10 am -
1 stop6h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![JetBlue logo]()
$176
This Frontier deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/139:17 pm -
1 stop13h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Frontier logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:32 pm -
2 stops24h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:54 pm -
2 stops40h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Frontier logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:53 pm -
2 stops40h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:51 pm -
2 stops41h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$297
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:15 pm -
2 stops17h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![American Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:28 am -
2 stops30h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:28 am -
2 stops17h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/137:26 pm -
3 stops33h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$323
This Expedia deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:16 pm -
1 stop15h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Frontier logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:13 pm -
3 stops32h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$339
Find flight deals from Columbus to South America
Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated November 7, 2026.
Round-trip from | $387 (JetBlue) |
|---|---|
One-way from | $176 (Priceline) |
Popular in | August |
Cheapest in | April |
Average price | $1,715 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 7, 2026.
Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Mon 11/30
6:10 am-12:45 pm
1 stop6h 35m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$176
ColumbusMedellín
CMH Columbus - MDE Medellín Jose Maria Cordova Intl
CMHMDE
Columbus
Sun 12/6
5:32 pm-6:20 pm
2 stops24h 48m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$281
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Mon 11/30
8:15 pm-1:32 pm
2 stops17h 17m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$303
ColumbusBogotá
CMH Columbus - BOG Bogotá El Dorado
CMHBOG
Columbus
Tue 11/24
7:58 pm-11:51 am
3 stops39h 53m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$303
ColumbusBogotá
CMH Columbus - BOG Bogotá El Dorado
CMHBOG
Columbus
Fri 11/27
10:28 am-3:30 am
2 stops17h 02m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$322
ColumbusSantiago
CMH Columbus - SCL Santiago Arturo Merino Benitez
CMHSCL
Columbus
Thu 12/31
7:48 pm-6:38 am
3 stops32h 50m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$352
ColumbusLima
CMH Columbus - LIM Lima J Chavez Intl
CMHLIM
Columbus
Sat 3/13
9:30 am-3:15 am
2 stops41h 45m
Lima J Chavez Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$366
ColumbusBogotá
CMH Columbus - BOG Bogotá El Dorado
CMHBOG
Columbus
Thu 11/19
1:16 pm-7:05 am
2 stops17h 49m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$367
ColumbusMedellín
CMH Columbus - MDE Medellín Jose Maria Cordova Intl
CMHMDE
Columbus
Sat 12/19
7:26 pm-12:00 pm
2 stops40h 34m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$370
ColumbusMedellín
CMH Columbus - MDE Medellín Jose Maria Cordova Intl
CMHMDE
Columbus
Tue 12/22
7:54 pm-8:15 am
3 stops36h 21m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$370
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Columbus to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
CMH-CTG
CMH-BOG
CMH-LIM
CMH-MDE
CMH-UIO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to South America
CMH-0SA
CMH-CTG
CMH-BOG
CMH-LIM
CMH-MDE
What is the cheapest month to book a flight from Columbus Airport to South America?
Currently, March is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $664). Flying from Columbus Airport to South America in December is currently the most expensive (average of $1,108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated November 7, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from Columbus Airport to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Columbus to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbus to South America by cabin class
Find flights from Columbus to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and South America flights
Browse other Columbus and South America flight options. Last updated on November 7, 2026.
Popular flight searches
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Fly to South America countries
Consider these flights traveling to countries located in South America.
Columbus to South America flights
Consider these flights traveling from Columbus to South America.
Top 4 airlines flying from Columbus to South America
Discover the top 4 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$491 | Average$826 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$563 | Average$1,136 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$580 | Average$959 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$614 | Average$907 | FlexibilityNo cancel fee | On-time81% |