HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South America

$94+ Cheap flights from Columbus (CMH) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbus to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Columbus to South America

Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated August 20, 2025.

Round-trip from

$254
(Cheapflightsfares)

One-way from

$94
(Cheapflightsfares)
From Columbus to South America
Search Deals
One-way flight from Columbus to South America
Search Deals

Find flight deals from Columbus to South America

Cheapest flights from Columbus to South America
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:15 amCMH - MDE
1 stop8h 59mSpirit Airlines
Wed 9/241:24 amMDE - CMH
1 stop17h 38mSpirit Airlines
Deal found 8/19$254
This Cheapflightsfares deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:15 amCMH - MDE
1 stop8h 59mSpirit Airlines
Thu 9/251:24 amMDE - CMH
1 stop16h 34mSpirit Airlines
Deal found 8/19$264
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:45 amCMH - CTG
1 stop6h 23mSpirit Airlines
Mon 11/172:16 pmCTG - CMH
1 stop6h 56mSpirit Airlines
Deal found 8/18$272
This Cheapflightsfares deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/165:15 amCMH - MDE
1 stop8h 59mSpirit Airlines
Wed 9/171:24 amMDE - CMH
1 stop17h 38mSpirit Airlines
Deal found 8/19$274
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:45 amCMH - CTG
1 stop6h 23mSpirit Airlines
Tue 11/112:16 pmCTG - CMH
1 stop6h 56mSpirit Airlines
Deal found 8/19$284
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/28:20 pmCMH - CTG
1 stop17h 03mSpirit Airlines
Thu 10/161:32 pmCTG - CMH
1 stop21h 18mSpirit Airlines
Deal found 8/19$286
This Cheapflightsfares deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:15 amCMH - MDE
1 stop8h 59mSpirit Airlines
Sat 9/271:24 amMDE - CMH
1 stop9h 17mSpirit Airlines
Deal found 8/17$289
This FlightHub deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/310:50 amCMH - CTG
1 stop26h 18mSpirit Airlines
Sun 12/72:16 pmCTG - CMH
1 stop6h 56mSpirit Airlines
Deal found 8/20$307
This Cheapflightsfares deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/25:15 amCMH - MDE
1 stop9h 07mSpirit Airlines
Thu 9/41:24 amMDE - CMH
1 stop9h 17mSpirit Airlines
Deal found 8/19$313
This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/245:15 amCMH - MDE
1 stop20h 13mSpirit Airlines
Sat 9/271:24 amMDE - CMH
1 stop9h 17mSpirit Airlines
Deal found 8/17$314
This Cheapflightsfares deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/175:15 amCMH - BOG
1 stop8h 55mSpirit Airlines
Wed 9/242:05 pmBOG - CMH
2 stops20h 21mSpirit Airlines
Deal found 8/19$320
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/168:19 pmCMH - CTG
2 stops17h 06mSpirit Airlines
Sun 10/191:32 pmCTG - CMH
1 stop21h 18mSpirit Airlines
Deal found 8/18$321

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.

Fly from

Columbus

Fly to

South America

Route

Depart

Return

Price

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 9/23

5:15 am-1:14 pm

1 stop8h 59m

Medellín Jose Maria Cordova Intl

Wed 9/24

1:24 am-8:02 pm

1 stop17h 38m

$254

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 9/23

5:15 am-1:14 pm

1 stop8h 59m

Medellín Jose Maria Cordova Intl

Thu 9/25

1:24 am-6:58 pm

1 stop16h 34m

$264

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Wed 11/12

6:45 am-1:08 pm

1 stop6h 23m

Cartagena Rafael Nunez

Mon 11/17

2:16 pm-9:12 pm

1 stop6h 56m

$272

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 9/16

5:15 am-1:14 pm

1 stop8h 59m

Medellín Jose Maria Cordova Intl

Wed 9/17

1:24 am-8:02 pm

1 stop17h 38m

$274

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Thu 11/6

6:45 am-1:08 pm

1 stop6h 23m

Cartagena Rafael Nunez

Tue 11/11

2:16 pm-9:12 pm

1 stop6h 56m

$284

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Thu 10/2

8:20 pm-12:23 pm

1 stop17h 03m

Cartagena Rafael Nunez

Thu 10/16

1:32 pm-11:50 am

1 stop21h 18m

$286

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 9/23

5:15 am-1:14 pm

1 stop8h 59m

Medellín Jose Maria Cordova Intl

Sat 9/27

1:24 am-11:41 am

1 stop9h 17m

$289

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Wed 9/17

5:15 am-1:10 pm

1 stop8h 55m

Bogotá El Dorado

Wed 9/24

2:05 pm-11:26 am

2 stops20h 21m

$320

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Thu 10/16

8:19 pm-12:25 pm

2 stops17h 06m

Cartagena Rafael Nunez

Sun 10/19

1:32 pm-11:50 am

1 stop21h 18m

$321

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Mon 10/6

5:15 am-1:15 pm

1 stop9h 00m

Bogotá El Dorado

Mon 10/13

2:10 pm-11:27 am

2 stops20h 17m

$321

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/20

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Columbus to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to South America

What is the cheapest month to book a flight from Columbus Airport to South America?

Currently, May is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $359). Flying from Columbus Airport to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SA?

Find hourly flight availability from Columbus to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Columbus Airport to South America as you normally would.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated August 20, 2025.
Get a feel of what it's like to fly with Delta, LATAM Airlines, and United Airlines from Columbus Airport to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,844 reviews
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,928 reviews
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Spirit Airlines
6.3
Okay
8,039 reviews
Delta
8.0
Very good
7,982 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus Airport to South America?

    Spirit Airlines and Avianca can get you from Columbus Airport to South America in just under 8h 59m. Your travel time can differ by up to 8h 54m. Airlines will cover a distance of 2382 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Columbus Airport to South America?

    When deciding which route to take from Columbus Airport to South America consider Columbus - Medellín Jose Maria Cordova Intl, Columbus - Buenos Aires Ministro Pistarini or Columbus - Bogotá El Dorado as they are the most popular.

  • Can I find deals for flights from Columbus to South America that include hotel bookings?

    Yes. In addition to deals on Columbus to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to South America.

  • Can I find deals for business class flights from Columbus to South America?

    Yes. Cheapflights offers flight deals from Columbus to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to South America?

    Currently, May is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $359). Flying from Columbus Airport to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Columbus to South America

See prices for flight routes from nearby airports that may be better suited for you.
Columbus to John F Kennedy Intl flights
Columbus to Seattle flights
Columbus to LaGuardia flights
Columbus to Newark flights
Columbus to Denver flights
Columbus to O'Hare Intl flights
Columbus to Orlando flights
Columbus to Fort Lauderdale flights
Columbus to Boston flights
Columbus to Las Vegas flights
Columbus to Miami flights
Columbus to Cancún flights
Columbus to Atlanta flights
Columbus to Salt Lake City flights
Columbus to Dallas/Fort Worth flights
Columbus to San Francisco flights
Columbus to Sky Harbor Intl flights
Columbus to Hobby flights
Columbus to Dulles Intl flights
Columbus to Omaha flights
Columbus to George Bush Intcntl flights
Columbus to Cozumel flights
Columbus to Los Angeles flights
Columbus to Tampa flights
Columbus to Minneapolis flights
Columbus to Nashville flights
Columbus to Midway flights
Columbus to Baltimore flights
Columbus to New Orleans flights
Columbus to Luis Munoz Marin Intl flights
Columbus to Philadelphia flights
Columbus to Narita flights
Columbus to Haneda flights
Columbus to Honolulu flights
Columbus to Ontario flights
Columbus to Reagan-National flights
Columbus to San Diego flights
Columbus to Portland flights
Columbus to Love Field flights
Columbus to Fort Myers flights
Columbus to Sarasota flights
Columbus to Savannah flights
Columbus to Oranjestad flights
Columbus to Raleigh flights
Columbus to Jackson flights
Columbus to Austin flights
Columbus to Charleston flights
Columbus to Pearson Intl flights
Columbus to Burbank flights
Columbus to West Palm Beach flights

Top 6 airlines flying from Columbus to South America

Discover the top 6 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$259Average$421FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$370Average$881FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$401Average$875FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$423Average$847FlexibilityNo cancel feeOn-time71%
DeltaCheapest$539Average$965FlexibilityNo cancel feeOn-timeN/A
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.