$162+ Cheap flights from Columbus (CMH) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Aug 23 — Aug 301
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Columbus to South AmericaExplore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:50 pm
CMH
- CTG
2 stops19h 45m
American Airlines
Tue 8/253:15 pm
CTG
- CMH
2 stops19h 14m
American Airlines
Deal found 7/22![American Airlines logo]()
$382
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am
CMH
- CTG
1 stop7h 35m
American Airlines
Tue 10/271:35 pm
CTG
- CMH
1 stop10h 02m
American Airlines
Deal found 7/23![American Airlines logo]()
$417
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:06 pm
CMH
- CTG
2 stops20h 09m
American Airlines
Thu 9/33:15 pm
CTG
- CMH
2 stops17h 54m
American Airlines
Deal found 7/22![American Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:16 pm
CMH
- CTG
1 stop18h 19m
American Airlines
Wed 11/112:35 pm
CTG
- CMH
1 stop7h 59m
American Airlines
Deal found 7/23![American Airlines logo]()
$427
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:19 pm
CMH
- CTG
1 stop23h 16m
American Airlines
Sat 10/311:35 pm
CTG
- CMH
1 stop10h 02m
American Airlines
Deal found 7/21![American Airlines logo]()
$438
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:03 pm
CMH
- CTG
2 stops18h 12m
American Airlines
Sat 8/223:15 pm
CTG
- CMH
2 stops20h 00m
American Airlines
Deal found 7/23![American Airlines logo]()
$502
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:00 am
CMH
- CTG
2 stops9h 17m
American Airlines
Fri 7/311:35 pm
CTG
- CMH
2 stops21h 19m
American Airlines
Deal found 7/22![American Airlines logo]()
$539
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:08 am
CMH
- CTG
1 stop6h 57m
Delta
Tue 8/252:30 pm
CTG
- CMH
1 stop9h 28m
Delta
Deal found 7/22![Delta logo]()
$559
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:00 am
CMH
- BOG
1 stop13h 30m
Delta
Thu 11/269:00 am
BOG
- CMH
1 stop9h 45m
Delta
Deal found 7/21![Delta logo]()
$615
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:15 am
CMH
- MDE
1 stop15h 55m
United Airlines
Tue 11/2410:40 am
MDE
- CMH
1 stop12h 54m
United Airlines
Deal found 7/21![United Airlines logo]()
$619
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:30 pm
CMH
- BOG
2 stops16h 40m
United Airlines
Tue 11/248:15 am
BOG
- CMH
1 stop15h 19m
United Airlines
Deal found 7/21![United Airlines logo]()
$620
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:51 am
CMH
- MDE
2 stops16h 19m
United Airlines
Thu 11/2610:40 am
MDE
- CMH
1 stop12h 54m
United Airlines
Deal found 7/21![United Airlines logo]()
$624
Best flights from Columbus to South AmericaDiscover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
Discover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am
CMH
- CTG
1 stop7h 35m
American Airlines
Tue 10/271:35 pm
CTG
- CMH
1 stop10h 02m
American Airlines
Deal found 7/23![American Airlines logo]()
$417
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:08 am
CMH
- CTG
1 stop6h 57m
Delta
Tue 8/252:30 pm
CTG
- CMH
1 stop9h 28m
Delta
Deal found 7/22![Delta logo]()
$559
This LATAM Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:05 am
CMH
- CTG
1 stop7h 10m
LATAM Airlines
Thu 9/32:30 pm
CTG
- CMH
1 stop9h 28m
LATAM Airlines
Deal found 7/21![LATAM Airlines logo]()
$559
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:15 am
CMH
- MDE
1 stop15h 55m
United Airlines
Wed 11/2510:40 am
MDE
- CMH
1 stop12h 54m
United Airlines
Deal found 7/19![United Airlines logo]()
$619
This Avianca deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/114:05 pm
CMH
- BOG
1 stop14h 50m
Multiple Airlines
Thu 8/1312:05 am
BOG
- CMH
1 stop12h 27m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$625
This Air Canada deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:30 am
CMH
- LIM
1 stop20h 40m
Air Canada
Wed 12/98:00 am
LIM
- CMH
1 stop13h 12m
Air Canada
Deal found 7/23![Air Canada logo]()
$647
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:54 pm
CMH
- CTG
2 stops18h 41m
American Airlines
Sat 10/311:35 pm
CTG
- CMH
2 stops23h 31m
American Airlines
Deal found 7/21![American Airlines logo]()
$512
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:37 pm
CMH
- CTG
2 stops20h 58m
American Airlines
Tue 8/253:15 pm
CTG
- CMH
2 stops19h 14m
American Airlines
Deal found 7/20![American Airlines logo]()
$552
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:20 am
CMH
- BOG
1 stop12h 10m
Delta
Mon 11/93:55 pm
BOG
- CMH
1 stop17h 05m
Delta
Deal found 7/19![Delta logo]()
$615
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:51 am
CMH
- BOG
2 stops16h 44m
United Airlines
Mon 11/98:15 am
BOG
- CMH
2 stops28h 50m
United Airlines
Deal found 7/19![United Airlines logo]()
$620
This oojo deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:15 am
CMH
- VCP
2 stops24h 15m
GOL
Wed 5/56:00 pm
VCP
- CMH
2 stops29h 55m
GOL
Deal found 7/20![GOL logo]()
$1,257
This KAYAK deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:30 am
CMH
- EZE
2 stops21h 06m
Copa Airlines
Mon 10/55:25 am
EZE
- CMH
2 stops29h 05m
Copa Airlines
Deal found 7/24![Copa Airlines logo]()
$1,343
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:51 am
CMH
- MDE
2 stops16h 19m
United Airlines
Wed 11/2510:40 am
MDE
- CMH
1 stop12h 54m
United Airlines
Deal found 7/21![United Airlines logo]()
$624
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:05 am
CMH
- CTG
2 stops14h 25m
Delta
Sun 9/134:30 am
CTG
- CMH
2 stops18h 45m
Delta
Deal found 7/23![Delta logo]()
$624
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:17 pm
CMH
- CTG
2 stops21h 18m
American Airlines
Mon 8/243:15 pm
CTG
- CMH
2 stops19h 59m
American Airlines
Deal found 7/21![American Airlines logo]()
$571
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:15 am
CMH
- MDE
1 stop15h 55m
United Airlines
Mon 11/2310:40 am
MDE
- CMH
2 stops26h 25m
United Airlines
Deal found 7/21![United Airlines logo]()
$624
This LATAM Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:20 am
CMH
- LIM
2 stops13h 10m
LATAM Airlines
Mon 11/2312:00 pm
LIM
- CMH
1 stop12h 10m
LATAM Airlines
Deal found 7/19![LATAM Airlines logo]()
$756
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am
CMH
- BOG
1 stop8h 25m
Delta
Sat 11/213:55 pm
BOG
- CMH
1 stop8h 15m
Delta
Deal found 7/21![Delta logo]()
$625
This Air Canada deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:30 am
CMH
- LIM
2 stops35h 00m
Multiple Airlines
Mon 11/308:00 am
LIM
- CMH
2 stops37h 12m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$767
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:39 am
CMH
- BOG
2 stops11h 38m
American Airlines
Tue 10/206:30 am
BOG
- CMH
2 stops11h 47m
American Airlines
Deal found 7/22![American Airlines logo]()
$620
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:15 am
CMH
- MDE
1 stop15h 55m
United Airlines
Mon 11/2310:40 am
MDE
- CMH
2 stops23h 28m
United Airlines
Deal found 7/21![United Airlines logo]()
$624
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am
CMH
- BOG
1 stop13h 30m
Delta
Sat 11/213:55 pm
BOG
- CMH
1 stop8h 15m
Delta
Deal found 7/21![Delta logo]()
$625
This KAYAK deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:05 am
CMH
- VCP
2 stops17h 55m
Azul
Thu 9/310:40 pm
VCP
- CMH
2 stops18h 22m
Azul
Deal found 7/19![Azul logo]()
$1,677
This LATAM Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:00 am
CMH
- LIM
2 stops14h 40m
LATAM Airlines
Wed 12/99:00 am
LIM
- CMH
2 stops15h 10m
LATAM Airlines
Deal found 7/23![LATAM Airlines logo]()
$824
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:15 am
CMH
- MDE
1 stop15h 55m
United Airlines
Wed 11/2510:40 am
MDE
- CMH
1 stop12h 54m
United Airlines
Deal found 7/19![United Airlines logo]()
$634
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:10 pm
CMH
- BOG
1 stop19h 15m
Delta
Fri 11/273:55 pm
BOG
- CMH
1 stop17h 05m
Delta
Deal found 7/21![Delta logo]()
$634
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:04 am
CMH
- BOG
2 stops14h 13m
American Airlines
Sat 9/126:30 am
BOG
- CMH
2 stops16h 23m
American Airlines
Deal found 7/22![American Airlines logo]()
$645
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am
CMH
- BOG
1 stop13h 30m
Delta
Fri 11/273:55 pm
BOG
- CMH
1 stop17h 05m
Delta
Deal found 7/21![Delta logo]()
$635
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:00 pm
CMH
- BOG
1 stop10h 05m
United Airlines
Sat 11/219:48 am
BOG
- CMH
1 stop12h 03m
United Airlines
Deal found 7/21![United Airlines logo]()
$635
This Air Canada deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/252:15 pm
CMH
- GRU
1 stop18h 35m
Air Canada
Thu 9/39:00 pm
GRU
- CMH
1 stop19h 22m
Air Canada
Deal found 7/19![Air Canada logo]()
$1,023
Last-minute flights from Columbus to South AmericaDiscover last-minute flight deals from Columbus to South America. Data last updated July 24, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to South America. Data last updated July 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:00 am
CMH
- CTG
2 stops9h 17m
American Airlines
Fri 7/311:35 pm
CTG
- CMH
2 stops21h 19m
American Airlines
Deal found 7/22![American Airlines logo]()
$539
This Avianca deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/114:05 pm
CMH
- BOG
1 stop14h 50m
Multiple Airlines
Thu 8/1312:05 am
BOG
- CMH
1 stop12h 27m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$625
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/139:03 pm
CMH
- CTG
2 stops18h 12m
American Airlines
Mon 8/173:15 pm
CTG
- CMH
2 stops19h 14m
American Airlines
Deal found 7/22![American Airlines logo]()
$601
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
CMH
- MDE
2 stops15h 15m
American Airlines
Mon 8/246:00 am
MDE
- CMH
1 stop17h 59m
American Airlines
Deal found 7/20![American Airlines logo]()
$662
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:03 pm
CMH
- CTG
2 stops18h 12m
American Airlines
Sat 8/223:15 pm
CTG
- CMH
2 stops20h 00m
American Airlines
Deal found 7/23![American Airlines logo]()
$502
This Expedia deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:59 pm
CMH
- CTG
1 stop23h 06m
LATAM Airlines
Sat 8/222:30 pm
CTG
- CMH
1 stop7h 48m
LATAM Airlines
Deal found 7/23![LATAM Airlines logo]()
$609
This LATAM Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:05 am
CMH
- MDE
2 stops15h 25m
LATAM Airlines
Wed 8/267:50 am
MDE
- CMH
2 stops16h 08m
LATAM Airlines
Deal found 7/19![LATAM Airlines logo]()
$640
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:16 am
CMH
- MDE
1 stop14h 59m
American Airlines
Thu 8/276:00 am
MDE
- CMH
1 stop17h 59m
American Airlines
Deal found 7/21![American Airlines logo]()
$642
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:17 pm
CMH
- CTG
2 stops21h 18m
American Airlines
Mon 8/243:15 pm
CTG
- CMH
2 stops19h 59m
American Airlines
Deal found 7/22![American Airlines logo]()
$571
This LATAM Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:05 am
CMH
- MDE
2 stops14h 00m
LATAM Airlines
Tue 8/258:55 am
MDE
- CMH
2 stops15h 03m
LATAM Airlines
Deal found 7/22![LATAM Airlines logo]()
$654
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:50 pm
CMH
- CTG
2 stops19h 45m
American Airlines
Tue 8/253:15 pm
CTG
- CMH
2 stops19h 14m
American Airlines
Deal found 7/22![American Airlines logo]()
$382
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:08 am
CMH
- CTG
1 stop6h 57m
Delta
Tue 8/252:30 pm
CTG
- CMH
1 stop9h 28m
Delta
Deal found 7/22![Delta logo]()
$559
One-way flights from Columbus to South AmericaSearch for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
Search for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:16 am
CMH
- CTG
1 stop7h 19m
American Airlines
Deal found 7/21![American Airlines logo]()
$162
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:14 pm
CMH
- CTG
2 stops19h 22m
American Airlines
Deal found 7/21![American Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:44 pm
CMH
- BOG
3 stops27h 36m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$214
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
CMH
- CTG
2 stops9h 15m
American Airlines
Deal found 7/23![American Airlines logo]()
$219
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/59:03 pm
CMH
- CTG
2 stops18h 12m
American Airlines
Deal found 7/23![American Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:44 pm
CMH
- BOG
3 stops44h 45m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:44 pm
CMH
- BOG
2 stops27h 26m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:45 pm
CMH
- CTG
3 stops29h 15m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:34 pm
CMH
- UIO
3 stops38h 51m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:10 pm
CMH
- BOG
2 stops27h 00m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3110:10 am
CMH
- BOG
3 stops28h 19m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:45 pm
CMH
- BOG
3 stops30h 21m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$274
Find flight deals from Columbus to South America
Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated July 24, 2026.
Round-trip from | $382 (American Airlines) |
|---|---|
One-way from | $162 (American Airlines) |
Popular in | February |
Cheapest in | April |
Average price | $711 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusCartagena
CMH - CTG
CMHCTG
Columbus
Tue 10/20
6:00 am-12:35 pm
1 stop7h 35m
Cartagena Rafael Nunez
Tue 10/27
1:35 pm-12:37 am
1 stop10h 02m
$417
ColumbusCartagena
CMH - CTG
CMHCTG
Columbus
Fri 10/9
6:54 pm-12:35 pm
2 stops18h 41m
Cartagena Rafael Nunez
Sat 10/31
1:35 pm-2:06 pm
2 stops23h 31m
$512
ColumbusCartagena
CMH - CTG
CMHCTG
Columbus
Sat 8/22
4:37 pm-12:35 pm
2 stops20h 58m
Cartagena Rafael Nunez
Tue 8/25
3:15 pm-11:29 am
2 stops19h 14m
$552
Quickest round-trip
ColumbusCartagena
CMH - CTG
CMHCTG
Columbus
Sat 8/22
7:08 am-1:05 pm
1 stop6h 57m
Cartagena Rafael Nunez
Tue 8/25
2:30 pm-12:58 am
1 stop9h 28m
$559
ColumbusCartagena
CMH - CTG
CMHCTG
Columbus
Tue 9/1
7:05 am-1:15 pm
1 stop7h 10m
Cartagena Rafael Nunez
Thu 9/3
2:30 pm-12:58 am
1 stop9h 28m
$559
ColumbusCartagena
CMH - CTG
CMHCTG
Columbus
Fri 8/21
4:17 pm-12:35 pm
2 stops21h 18m
Cartagena Rafael Nunez
Mon 8/24
3:15 pm-12:14 pm
2 stops19h 59m
$571
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Mon 11/2
7:20 am-7:30 pm
1 stop12h 10m
Bogotá El Dorado
Mon 11/9
3:55 pm-9:00 am
1 stop17h 05m
$615
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Wed 11/11
6:15 am-10:10 pm
1 stop15h 55m
Medellín Jose Maria Cordova Intl
Wed 11/25
10:40 am-11:34 pm
1 stop12h 54m
$619
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Mon 11/2
5:51 am-10:35 pm
2 stops16h 44m
Bogotá El Dorado
Mon 11/9
8:15 am-1:05 pm
2 stops28h 50m
$620
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Fri 9/25
10:39 am-9:17 pm
2 stops11h 38m
Bogotá El Dorado
Tue 10/20
6:30 am-7:17 pm
2 stops11h 47m
$620
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Columbus to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
CMH-CTG
CMH-BOG
CMH-MDE
CMH-UIO
CMH-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to South America
CMH-0SA
CMH-CTG
CMH-BOG
CMH-MDE
CMH-UIO
What is the cheapest month to book a flight from Columbus Airport to South America?
Currently, March is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $650). Flying from Columbus Airport to South America in December is currently the most expensive (average of $1,195). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 24, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from Columbus Airport to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Columbus to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbus to South America by cabin class
Find flights from Columbus to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and South America flights
Browse other Columbus and South America flight options. Last updated on July 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Columbus to South America flights
Consider these flights traveling from Columbus to South America.
Top 4 airlines flying from Columbus to South America
Discover the top 4 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$552 | Average$773 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$563 | Average$987 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$575 | Average$854 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$614 | Average$876 | FlexibilityNo cancel fee | On-time81% |