$297+ Cheap flights from Columbus (CMH) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/14. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Jul 3 — Jul 101
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Columbus to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to South America
Cheapest
Best
Last-minute
One-way
Cheapest flights from Columbus to South AmericaExplore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 3, 2026.
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 3, 2026.
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:46 pm
CMH
- CTG
2 stops20h 31m
American Airlines
Tue 7/213:17 pm
CTG
- CMH
2 stops20h 04m
American Airlines
Deal found 6/2![American Airlines logo]()
$494
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:46 pm
CMH
- CTG
2 stops20h 31m
American Airlines
Sun 7/193:17 pm
CTG
- CMH
2 stops20h 04m
American Airlines
Deal found 6/1![American Airlines logo]()
$524
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:04 am
CMH
- CTG
2 stops9h 13m
American Airlines
Tue 7/141:35 pm
CTG
- CMH
1 stop10h 02m
American Airlines
Deal found 6/1![American Airlines logo]()
$562
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:08 am
CMH
- CTG
1 stop8h 27m
American Airlines
Mon 7/201:35 pm
CTG
- CMH
2 stops19h 35m
American Airlines
Deal found 5/30![American Airlines logo]()
$568
This Gotogate deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:30 am
CMH
- LIM
2 stops25h 15m
Multiple Airlines
Sun 11/222:55 am
LIM
- CMH
2 stops18h 01m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$576
This Gotogate deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:30 am
CMH
- LIM
2 stops25h 15m
Air Canada
Sun 12/132:55 am
LIM
- CMH
2 stops18h 01m
Air Canada
Deal found 5/31![Air Canada logo]()
$579
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:45 am
CMH
- CTG
1 stop6h 20m
American Airlines
Tue 10/272:05 pm
CTG
- CMH
1 stop9h 35m
American Airlines
Deal found 5/29![American Airlines logo]()
$582
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:26 pm
CMH
- CTG
2 stops20h 09m
American Airlines
Mon 7/273:17 pm
CTG
- CMH
2 stops20h 04m
American Airlines
Deal found 6/1![American Airlines logo]()
$583
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:00 am
CMH
- CTG
1 stop6h 35m
American Airlines
Tue 7/213:17 pm
CTG
- CMH
2 stops20h 04m
American Airlines
Deal found 6/1![American Airlines logo]()
$594
This Air Canada deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:30 am
CMH
- LIM
2 stops31h 00m
Multiple Airlines
Mon 11/235:35 pm
LIM
- CMH
2 stops27h 21m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$597
This Justfly.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:30 am
CMH
- LIM
2 stops17h 45m
Air Canada
Fri 11/132:55 am
LIM
- CMH
2 stops18h 01m
Air Canada
Deal found 5/31![Air Canada logo]()
$601
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:44 pm
CMH
- CTG
2 stops18h 21m
American Airlines
Tue 10/202:05 pm
CTG
- CMH
1 stop9h 35m
American Airlines
Deal found 5/30![American Airlines logo]()
$611
Best flights from Columbus to South AmericaDiscover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 3, 2026.
Discover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 3, 2026.
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:45 am
CMH
- CTG
1 stop6h 20m
American Airlines
Tue 10/272:05 pm
CTG
- CMH
1 stop9h 35m
American Airlines
Deal found 5/29![American Airlines logo]()
$582
This KAYAK deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:30 am
CMH
- LIM
2 stops25h 15m
Multiple Airlines
Sun 11/222:55 am
LIM
- CMH
2 stops18h 01m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$597
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/912:48 pm
CMH
- BOG
1 stop7h 27m
Delta
Mon 6/155:15 pm
BOG
- CMH
2 stops17h 36m
Delta
Deal found 5/30![Delta logo]()
$665
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/92:19 pm
CMH
- BOG
2 stops15h 06m
United Airlines
Thu 6/117:20 am
BOG
- CMH
1 stop12h 37m
United Airlines
Deal found 5/29![United Airlines logo]()
$670
This Avianca deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:58 pm
CMH
- CTG
3 stops17h 37m
Avianca
Tue 10/278:00 pm
CTG
- CMH
2 stops12h 35m
Avianca
Deal found 5/29![Avianca logo]()
$681
This KAYAK deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:54 pm
CMH
- BOG
2 stops27h 06m
Azul
Tue 7/711:10 pm
BOG
- CMH
1 stop12h 23m
Azul
Deal found 5/31![Azul logo]()
$694
This Copa Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:20 am
CMH
- LIM
2 stops21h 00m
Copa Airlines
Tue 10/207:00 am
LIM
- CMH
2 stops25h 36m
Copa Airlines
Deal found 6/1![Copa Airlines logo]()
$792
This Air Canada deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:30 am
CMH
- GRU
1 stop21h 30m
Air Canada
Sun 11/159:45 pm
GRU
- CMH
2 stops25h 11m
Air Canada
Deal found 6/2![Air Canada logo]()
$833
This LATAM Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:05 pm
CMH
- SCL
1 stop17h 45m
LATAM Airlines
Sat 12/129:50 pm
SCL
- CMH
1 stop22h 55m
LATAM Airlines
Deal found 5/30![LATAM Airlines logo]()
$1,020
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:00 am
CMH
- CTG
1 stop6h 35m
American Airlines
Tue 7/213:17 pm
CTG
- CMH
2 stops20h 04m
American Airlines
Deal found 6/1![American Airlines logo]()
$594
This FlightHub deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:30 am
CMH
- LIM
2 stops41h 45m
Multiple Airlines
Sun 11/222:55 am
LIM
- CMH
2 stops18h 01m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$601
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:05 am
CMH
- BOG
1 stop7h 35m
Delta
Wed 6/172:55 pm
BOG
- CMH
1 stop17h 12m
Delta
Deal found 6/1![Delta logo]()
$665
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:01 pm
CMH
- CTG
2 stops19h 04m
American Airlines
Tue 11/34:15 pm
CTG
- CMH
1 stop8h 20m
American Airlines
Deal found 5/30![American Airlines logo]()
$611
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:30 am
CMH
- MDE
1 stop15h 40m
United Airlines
Sun 7/59:45 am
MDE
- CMH
1 stop13h 14m
United Airlines
Deal found 5/29![United Airlines logo]()
$677
This KAYAK deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/98:19 am
CMH
- BOG
1 stop14h 41m
Multiple Airlines
Mon 6/158:30 am
BOG
- CMH
1 stop14h 29m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$664
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:01 pm
CMH
- CTG
2 stops19h 04m
American Airlines
Sat 10/242:05 pm
CTG
- CMH
2 stops19h 07m
American Airlines
Deal found 6/2![American Airlines logo]()
$611
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:30 am
CMH
- UIO
1 stop17h 55m
United Airlines
Sun 8/2312:35 am
UIO
- CMH
1 stop9h 28m
United Airlines
Deal found 5/29![United Airlines logo]()
$706
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:02 am
CMH
- UIO
2 stops19h 41m
Delta
Mon 8/246:50 pm
UIO
- CMH
2 stops18h 02m
Delta
Deal found 5/29![Delta logo]()
$711
This Copa Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:58 pm
CMH
- LIM
2 stops20h 42m
Copa Airlines
Sun 10/2510:30 am
LIM
- CMH
2 stops21h 08m
Copa Airlines
Deal found 5/31![Copa Airlines logo]()
$792
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:14 pm
CMH
- CTG
2 stops19h 21m
American Airlines
Mon 8/33:17 pm
CTG
- CMH
2 stops20h 04m
American Airlines
Deal found 5/29![American Airlines logo]()
$615
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:30 am
CMH
- UIO
1 stop17h 55m
United Airlines
Sun 8/2312:35 am
UIO
- CMH
1 stop9h 28m
United Airlines
Deal found 5/29![United Airlines logo]()
$706
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:10 am
CMH
- UIO
1 stop11h 49m
Delta
Mon 8/246:50 pm
UIO
- CMH
2 stops15h 48m
Delta
Deal found 5/29![Delta logo]()
$711
This Copa Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:20 am
CMH
- LIM
2 stops18h 25m
Copa Airlines
Sun 9/134:00 am
LIM
- CMH
2 stops28h 30m
Copa Airlines
Deal found 6/2![Copa Airlines logo]()
$792
This Air Canada deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/289:30 am
CMH
- GIG
1 stop24h 35m
Air Canada
Wed 12/29:00 pm
GIG
- CMH
1 stop25h 56m
Air Canada
Deal found 6/2![Air Canada logo]()
$875
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:01 pm
CMH
- MDE
2 stops11h 47m
American Airlines
Thu 8/1312:30 am
MDE
- CMH
2 stops10h 44m
American Airlines
Deal found 5/30![American Airlines logo]()
$624
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:30 am
CMH
- BOG
1 stop13h 50m
United Airlines
Sun 7/1211:10 pm
BOG
- CMH
1 stop10h 30m
United Airlines
Deal found 5/29![United Airlines logo]()
$718
This LATAM Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:50 pm
CMH
- SCL
2 stops23h 45m
LATAM Airlines
Sun 10/2511:25 pm
SCL
- CMH
2 stops20h 20m
LATAM Airlines
Deal found 6/1![LATAM Airlines logo]()
$1,025
This American Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:15 am
CMH
- CTG
1 stop7h 20m
American Airlines
Thu 8/271:35 pm
CTG
- CMH
1 stop8h 12m
American Airlines
Deal found 5/31![American Airlines logo]()
$648
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:07 am
CMH
- LIM
1 stop14h 53m
Delta
Sun 10/412:05 am
LIM
- CMH
1 stop16h 33m
Delta
Deal found 5/30![Delta logo]()
$789
This Delta deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:05 am
CMH
- LIM
1 stop19h 55m
Delta
Sun 11/2212:05 am
LIM
- CMH
1 stop17h 21m
Delta
Deal found 5/31![Delta logo]()
$789
Last-minute flights from Columbus to South AmericaDiscover last-minute flight deals from Columbus to South America. Data last updated June 3, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to South America. Data last updated June 3, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:14 pm
CMH
- BOG
1 stop9h 46m
United Airlines
Fri 8/2111:10 pm
BOG
- CMH
1 stop17h 51m
United Airlines
Deal found 6/1![United Airlines logo]()
$650
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:09 pm
CMH
- CTG
2 stops19h 26m
American Airlines
Tue 6/233:13 pm
CTG
- CMH
2 stops20h 08m
American Airlines
Deal found 6/1![American Airlines logo]()
$624
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:04 am
CMH
- CTG
2 stops9h 13m
American Airlines
Tue 7/141:35 pm
CTG
- CMH
1 stop10h 02m
American Airlines
Deal found 6/1![American Airlines logo]()
$562
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:08 am
CMH
- CTG
1 stop8h 27m
American Airlines
Mon 7/201:35 pm
CTG
- CMH
2 stops19h 35m
American Airlines
Deal found 5/30![American Airlines logo]()
$568
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/131:01 pm
CMH
- MDE
2 stops11h 47m
American Airlines
Wed 7/2212:30 am
MDE
- CMH
1 stop11h 55m
American Airlines
Deal found 6/1![American Airlines logo]()
$648
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:46 pm
CMH
- CTG
2 stops20h 31m
American Airlines
Tue 7/213:17 pm
CTG
- CMH
2 stops20h 04m
American Airlines
Deal found 6/2![American Airlines logo]()
$494
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:46 pm
CMH
- CTG
2 stops20h 31m
American Airlines
Sun 7/193:17 pm
CTG
- CMH
2 stops20h 04m
American Airlines
Deal found 6/1![American Airlines logo]()
$524
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:00 am
CMH
- CTG
1 stop6h 35m
American Airlines
Tue 7/213:17 pm
CTG
- CMH
2 stops20h 04m
American Airlines
Deal found 6/1![American Airlines logo]()
$594
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:26 pm
CMH
- CTG
2 stops20h 09m
American Airlines
Mon 7/273:17 pm
CTG
- CMH
2 stops20h 04m
American Airlines
Deal found 6/1![American Airlines logo]()
$583
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:01 pm
CMH
- MDE
2 stops11h 47m
American Airlines
Thu 8/1312:30 am
MDE
- CMH
2 stops10h 44m
American Airlines
Deal found 5/30![American Airlines logo]()
$624
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:14 pm
CMH
- CTG
2 stops19h 21m
American Airlines
Mon 8/33:17 pm
CTG
- CMH
2 stops20h 04m
American Airlines
Deal found 5/29![American Airlines logo]()
$615
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:08 pm
CMH
- BOG
1 stop18h 32m
Delta
Sun 8/92:55 pm
BOG
- CMH
1 stop17h 02m
Delta
Deal found 6/1![Delta logo]()
$635
One-way flights from Columbus to South AmericaSearch for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated June 3, 2026.
Search for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated June 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:00 pm
CMH
- LIM
3 stops36h 01m
Multiple Airlines
Deal found 5/29![Multiple Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:54 pm
CMH
- MDE
3 stops51h 41m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$321
This Avianca deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:00 am
CMH
- MDE
2 stops17h 25m
Avianca
Deal found 6/1![Avianca logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:58 pm
CMH
- LIM
3 stops33h 03m
Multiple Airlines
Deal found 5/29![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:58 pm
CMH
- MDE
3 stops36h 17m
Multiple Airlines
Deal found 5/29![Multiple Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:08 am
CMH
- CTG
1 stop10h 09m
American Airlines
Deal found 6/2![American Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:00 pm
CMH
- LIM
3 stops36h 01m
Multiple Airlines
Deal found 5/29![Multiple Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:58 pm
CMH
- LIM
3 stops33h 03m
Multiple Airlines
Deal found 5/29![Multiple Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:16 pm
CMH
- MDE
3 stops44h 59m
Multiple Airlines
Deal found 5/29![Multiple Airlines logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:06 pm
CMH
- BOG
2 stops31h 16m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:00 pm
CMH
- BOG
3 stops47h 00m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:58 pm
CMH
- MDE
3 stops46h 02m
Multiple Airlines
Deal found 5/29![Multiple Airlines logo]()
$367
Find flight deals from Columbus to South America
Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated June 3, 2026.
Round-trip from | $494 (American Airlines) |
|---|---|
One-way from | $297 (Kiwi.com) |
Popular in | February |
Cheapest in | April |
Average price | $718 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 3, 2026.
Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusCartagena
CMH - CTG
CMHCTG
Columbus
Tue 10/20
6:45 am-12:05 pm
1 stop6h 20m
Cartagena Rafael Nunez
Tue 10/27
2:05 pm-12:40 am
1 stop9h 35m
$582
ColumbusCartagena
CMH - CTG
CMHCTG
Columbus
Thu 7/16
7:00 am-12:35 pm
1 stop6h 35m
Cartagena Rafael Nunez
Tue 7/21
3:17 pm-12:21 pm
2 stops20h 04m
$594
ColumbusLima
CMH - LIM
CMHLIM
Columbus
Wed 11/4
9:30 am-10:45 am
2 stops25h 15m
Lima J Chavez Intl
Sun 11/22
2:55 am-8:56 pm
2 stops18h 01m
$597
ColumbusLima
CMH - LIM
CMHLIM
Columbus
Sat 11/7
9:30 am-3:15 am
2 stops41h 45m
Lima J Chavez Intl
Sun 11/22
2:55 am-8:56 pm
2 stops18h 01m
$601
ColumbusCartagena
CMH - CTG
CMHCTG
Columbus
Wed 10/28
6:01 pm-12:05 pm
2 stops19h 04m
Cartagena Rafael Nunez
Tue 11/3
4:15 pm-12:35 am
1 stop8h 20m
$611
ColumbusCartagena
CMH - CTG
CMHCTG
Columbus
Sun 10/18
6:01 pm-12:05 pm
2 stops19h 04m
Cartagena Rafael Nunez
Sat 10/24
2:05 pm-10:12 am
2 stops19h 07m
$611
ColumbusCartagena
CMH - CTG
CMHCTG
Columbus
Sun 7/26
6:14 pm-12:35 pm
2 stops19h 21m
Cartagena Rafael Nunez
Mon 8/3
3:17 pm-12:21 pm
2 stops20h 04m
$615
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Sat 7/25
1:01 pm-11:48 pm
2 stops11h 47m
Medellín Jose Maria Cordova Intl
Thu 8/13
12:30 am-12:14 pm
2 stops10h 44m
$624
Quickest round-trip
ColumbusCartagena
CMH - CTG
CMHCTG
Columbus
Mon 8/24
6:15 am-12:35 pm
1 stop7h 20m
Cartagena Rafael Nunez
Thu 8/27
1:35 pm-10:47 pm
1 stop8h 12m
$648
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Tue 6/9
8:19 am-10:00 pm
1 stop14h 41m
Bogotá El Dorado
Mon 6/15
8:30 am-11:59 pm
1 stop14h 29m
$664
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Columbus to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
CMH-CTG
CMH-LIM
CMH-BOG
CMH-GRU
CMH-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to South America
CMH-0SA
CMH-CTG
CMH-LIM
CMH-BOG
CMH-GRU
What is the cheapest month to book a flight from Columbus Airport to South America?
Currently, October is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $225). Flying from Columbus Airport to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Columbus Airport to South America?
To ensure you get the cheapest price possible for a flight from Columbus Airport to South America, you should look to book at least 21 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated June 3, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from Columbus Airport to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top countries
Top destinations
Alternative routes for Columbus to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbus to South America by cabin class
Find flights from Columbus to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and South America flights
Browse other Columbus and South America flight options. Last updated on June 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Columbus to South America flights
Consider these flights traveling from Columbus to South America.
Top 4 airlines flying from Columbus to South America
Discover the top 4 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$552 | Average$810 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$552 | Average$754 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$658 | Average$922 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$962 | Average$1,449 | FlexibilityNo cancel fee | On-time69% |