$199+ Cheap flights from Columbus (CMH) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
May 29 — Jun 51
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to South America
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Cheapest flights from Columbus to South AmericaExplore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
This Trip.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:48 pm
CMH
- MDE
1 stop19h 57m
Multiple Airlines
Sun 6/212:10 pm
MDE
- CMH
2 stops29h 03m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$512
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:48 pm
CMH
- MDE
1 stop17h 12m
Multiple Airlines
Thu 5/217:00 am
MDE
- CMH
2 stops11h 53m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$533
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
CMH
- MDE
1 stop7h 43m
Multiple Airlines
Sun 5/1711:10 pm
MDE
- CMH
2 stops19h 43m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$544
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:05 pm
CMH
- MDE
2 stops39h 10m
Multiple Airlines
Thu 5/212:06 pm
MDE
- CMH
1 stop8h 50m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$546
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:48 pm
CMH
- MDE
1 stop17h 12m
Multiple Airlines
Fri 5/221:55 pm
MDE
- CMH
1 stop20h 21m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$547
This Cheapflightsfares deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:45 pm
CMH
- MDE
1 stop17h 19m
Spirit Airlines
Fri 7/242:26 pm
MDE
- CMH
1 stop7h 57m
Spirit Airlines
Deal found 4/27![Spirit Airlines logo]()
$555
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:48 pm
CMH
- MDE
1 stop17h 12m
Multiple Airlines
Wed 5/278:15 pm
MDE
- CMH
2 stops26h 41m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$556
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:00 am
CMH
- MDE
2 stops17h 35m
Multiple Airlines
Sun 5/249:45 am
MDE
- CMH
2 stops13h 11m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$560
This Gotogate deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:30 am
CMH
- LIM
1 stop20h 40m
Multiple Airlines
Mon 11/91:50 am
LIM
- CMH
2 stops19h 06m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$560
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:37 pm
CMH
- MDE
1 stop24h 23m
Multiple Airlines
Fri 5/221:55 pm
MDE
- CMH
1 stop20h 21m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$563
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:00 am
CMH
- MDE
1 stop7h 43m
Multiple Airlines
Fri 5/225:45 am
MDE
- CMH
2 stops13h 08m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$565
This Expedia deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:30 am
CMH
- LIM
1 stop20h 40m
Air Canada
Mon 11/98:00 am
LIM
- CMH
2 stops36h 56m
Air Canada
Deal found 4/28![Air Canada logo]()
$565
Best flights from Columbus to South AmericaDiscover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
Discover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:15 am
CMH
- MDE
1 stop15h 00m
American Airlines
Wed 9/165:50 am
MDE
- CMH
1 stop11h 23m
American Airlines
Deal found 4/26![American Airlines logo]()
$609
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am
CMH
- BOG
2 stops12h 50m
Delta
Mon 10/1211:00 am
BOG
- CMH
2 stops21h 00m
Delta
Deal found 4/27![Delta logo]()
$610
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:20 am
CMH
- BOG
1 stop13h 40m
United Airlines
Fri 10/301:30 am
BOG
- CMH
1 stop13h 20m
United Airlines
Deal found 4/27![United Airlines logo]()
$615
This eDestinos deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:00 am
CMH
- BOG
1 stop13h 15m
LATAM Airlines
Mon 6/2911:00 am
BOG
- CMH
2 stops21h 07m
LATAM Airlines
Deal found 4/24![LATAM Airlines logo]()
$619
This Cheapflightsfares deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:45 pm
CMH
- MDE
1 stop17h 19m
Spirit Airlines
Fri 8/142:26 pm
MDE
- CMH
1 stop7h 57m
Spirit Airlines
Deal found 4/24![Spirit Airlines logo]()
$640
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:58 pm
CMH
- MDE
2 stops36h 17m
Multiple Airlines
Mon 6/221:55 pm
MDE
- CMH
1 stop29h 18m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$641
This Copa Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am
CMH
- LIM
2 stops20h 20m
Copa Airlines
Sun 10/44:00 am
LIM
- CMH
2 stops27h 38m
Copa Airlines
Deal found 4/28![Copa Airlines logo]()
$732
This Air Canada deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/272:15 pm
CMH
- EZE
2 stops23h 15m
Air Canada
Mon 10/54:35 pm
EZE
- CMH
3 stops47h 47m
Air Canada
Deal found 4/27![Air Canada logo]()
$952
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:01 pm
CMH
- MDE
2 stops11h 57m
American Airlines
Fri 8/146:00 am
MDE
- CMH
1 stop17h 58m
American Airlines
Deal found 4/24![American Airlines logo]()
$614
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:00 am
CMH
- BOG
1 stop7h 40m
Delta
Mon 6/298:40 am
BOG
- CMH
2 stops12h 20m
Delta
Deal found 4/26![Delta logo]()
$620
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:11 pm
CMH
- BOG
1 stop11h 14m
United Airlines
Mon 9/711:10 pm
BOG
- CMH
1 stop12h 16m
United Airlines
Deal found 4/28![United Airlines logo]()
$629
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:47 pm
CMH
- BOG
1 stop29h 58m
Multiple Airlines
Sat 5/238:40 am
BOG
- CMH
1 stop27h 02m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$641
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
CMH
- MDE
2 stops14h 55m
American Airlines
Tue 10/135:45 am
MDE
- CMH
2 stops17h 48m
American Airlines
Deal found 4/28![American Airlines logo]()
$614
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:08 pm
CMH
- BOG
1 stop18h 32m
Delta
Thu 7/3011:00 am
BOG
- CMH
2 stops21h 02m
Delta
Deal found 4/25![Delta logo]()
$620
This KAYAK deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:00 am
CMH
- LIM
2 stops15h 35m
LATAM Airlines
Sun 9/2012:05 am
LIM
- CMH
1 stop16h 27m
LATAM Airlines
Deal found 4/28![LATAM Airlines logo]()
$729
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/204:09 pm
CMH
- MDE
2 stops30h 01m
United Airlines
Tue 6/239:45 am
MDE
- CMH
2 stops23h 12m
United Airlines
Deal found 4/26![United Airlines logo]()
$665
This Copa Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:10 am
CMH
- LIM
2 stops15h 10m
Copa Airlines
Mon 8/244:00 am
LIM
- CMH
2 stops27h 35m
Copa Airlines
Deal found 4/26![Copa Airlines logo]()
$732
This Mytrip deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:37 pm
CMH
- UIO
2 stops29h 03m
Multiple Airlines
Wed 6/175:20 pm
UIO
- CMH
2 stops25h 30m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$679
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:25 am
CMH
- BOG
2 stops12h 25m
Delta
Mon 9/711:00 am
BOG
- CMH
2 stops21h 40m
Delta
Deal found 4/28![Delta logo]()
$634
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:01 pm
CMH
- MDE
1 stop29h 09m
United Airlines
Mon 6/89:45 am
MDE
- CMH
1 stop13h 14m
United Airlines
Deal found 4/27![United Airlines logo]()
$669
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2212:59 pm
CMH
- UIO
2 stops11h 59m
American Airlines
Wed 7/2911:59 pm
UIO
- CMH
1 stop12h 03m
American Airlines
Deal found 4/24![American Airlines logo]()
$701
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:00 am
CMH
- BOG
1 stop14h 15m
Delta
Tue 7/282:55 pm
BOG
- CMH
1 stop8h 49m
Delta
Deal found 4/25![Delta logo]()
$639
This Copa Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/199:06 am
CMH
- LIM
2 stops17h 14m
Copa Airlines
Fri 7/244:40 pm
LIM
- CMH
2 stops16h 17m
Copa Airlines
Deal found 4/26![Copa Airlines logo]()
$804
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:55 pm
CMH
- MDE
2 stops25h 15m
United Airlines
Mon 6/89:45 am
MDE
- CMH
2 stops21h 53m
United Airlines
Deal found 4/27![United Airlines logo]()
$672
This Mytrip deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/111:37 pm
CMH
- UIO
2 stops29h 03m
Multiple Airlines
Thu 6/185:20 pm
UIO
- CMH
3 stops29h 03m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$763
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 pm
CMH
- LIM
1 stop10h 10m
American Airlines
Mon 9/2111:45 pm
LIM
- CMH
1 stop17h 28m
American Airlines
Deal found 4/28![American Airlines logo]()
$729
This Copa Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:00 am
CMH
- LIM
2 stops17h 20m
Copa Airlines
Thu 7/91:20 pm
LIM
- CMH
2 stops19h 29m
Copa Airlines
Deal found 4/26![Copa Airlines logo]()
$804
This LATAM Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:45 pm
CMH
- EZE
1 stop15h 00m
LATAM Airlines
Mon 9/73:55 am
EZE
- CMH
2 stops21h 04m
LATAM Airlines
Deal found 4/27![LATAM Airlines logo]()
$909
This Mytrip deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/81:37 pm
CMH
- LIM
2 stops16h 24m
Multiple Airlines
Sun 6/143:00 am
LIM
- CMH
2 stops35h 22m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$780
This Copa Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:54 pm
CMH
- LIM
2 stops24h 21m
Copa Airlines
Tue 7/2811:00 am
LIM
- CMH
2 stops21h 57m
Copa Airlines
Deal found 4/25![Copa Airlines logo]()
$804
Last-minute flights from Columbus to South AmericaDiscover last-minute flight deals from Columbus to South America. Data last updated April 29, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to South America. Data last updated April 29, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:47 pm
CMH
- BOG
1 stop29h 58m
Multiple Airlines
Sat 5/238:40 am
BOG
- CMH
2 stops31h 30m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$585
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
CMH
- MDE
1 stop7h 43m
Multiple Airlines
Sun 5/1711:10 pm
MDE
- CMH
2 stops19h 43m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$544
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:05 pm
CMH
- MDE
2 stops39h 10m
Multiple Airlines
Thu 5/212:06 pm
MDE
- CMH
1 stop8h 50m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$546
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:00 am
CMH
- MDE
1 stop7h 43m
Multiple Airlines
Fri 5/225:45 am
MDE
- CMH
2 stops13h 08m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$565
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:00 am
CMH
- MDE
1 stop7h 43m
Spirit Airlines
Thu 5/212:06 pm
MDE
- CMH
1 stop8h 50m
Spirit Airlines
Deal found 4/26![Spirit Airlines logo]()
$570
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:48 pm
CMH
- MDE
1 stop17h 12m
Multiple Airlines
Thu 5/217:00 am
MDE
- CMH
2 stops11h 53m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$533
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:48 pm
CMH
- MDE
1 stop17h 12m
Multiple Airlines
Fri 5/221:55 pm
MDE
- CMH
1 stop20h 21m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$547
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:48 pm
CMH
- MDE
1 stop17h 12m
Multiple Airlines
Wed 5/278:15 pm
MDE
- CMH
2 stops26h 41m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$556
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:48 pm
CMH
- MDE
1 stop17h 12m
Multiple Airlines
Sat 5/2312:40 pm
MDE
- CMH
2 stops23h 02m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$573
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:37 pm
CMH
- MDE
1 stop24h 23m
Multiple Airlines
Fri 5/221:55 pm
MDE
- CMH
1 stop20h 21m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$563
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:37 pm
CMH
- MDE
1 stop24h 23m
Multiple Airlines
Sun 5/245:45 am
MDE
- CMH
2 stops13h 20m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$581
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:00 am
CMH
- MDE
2 stops17h 35m
Multiple Airlines
Sun 5/249:45 am
MDE
- CMH
2 stops13h 11m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$560
One-way flights from Columbus to South AmericaSearch for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
Search for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:05 pm
CMH
- BOG
3 stops40h 15m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:28 pm
CMH
- MDE
3 stops41h 27m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:05 pm
CMH
- MDE
3 stops43h 58m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:05 pm
CMH
- BOG
3 stops33h 45m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:37 pm
CMH
- BOG
2 stops30h 38m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:48 pm
CMH
- BOG
2 stops28h 34m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$248
This Cheapflightsfares deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:45 pm
CMH
- MDE
1 stop17h 19m
Spirit Airlines
Deal found 4/28![Spirit Airlines logo]()
$249
This Spirit deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/126:00 am
CMH
- BOG
1 stop8h 12m
Spirit Airlines
Deal found 4/27![Spirit Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:37 pm
CMH
- MDE
2 stops19h 38m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/126:00 pm
CMH
- BOG
2 stops20h 12m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:37 pm
CMH
- UIO
3 stops35h 57m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:33 pm
CMH
- SCL
3 stops31h 02m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$327
Find flight deals from Columbus to South America
Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated April 29, 2026.
Round-trip from | $512 (Trip.com) |
|---|---|
One-way from | $199 (Kiwi.com) |
Popular in | February |
Cheapest in | October |
Average price | $388 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Sun 9/6
6:15 am-8:15 pm
1 stop15h 00m
Medellín Jose Maria Cordova Intl
Wed 9/16
5:50 am-6:13 pm
1 stop11h 23m
$609
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Mon 10/5
6:00 am-5:50 pm
2 stops12h 50m
Bogotá El Dorado
Mon 10/12
11:00 am-9:00 am
2 stops21h 00m
$610
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Sat 7/25
1:01 pm-11:58 pm
2 stops11h 57m
Medellín Jose Maria Cordova Intl
Fri 8/14
6:00 am-12:58 am
1 stop17h 58m
$614
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Tue 10/6
6:00 am-7:55 pm
2 stops14h 55m
Medellín Jose Maria Cordova Intl
Tue 10/13
5:45 am-12:33 am
2 stops17h 48m
$614
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Thu 10/1
9:20 am-10:00 pm
1 stop13h 40m
Bogotá El Dorado
Fri 10/30
1:30 am-3:50 pm
1 stop13h 20m
$615
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Sat 6/20
7:00 am-7:15 pm
1 stop13h 15m
Bogotá El Dorado
Mon 6/29
11:00 am-9:07 am
2 stops21h 07m
$619
Quickest round-trip
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Sat 6/20
7:00 am-1:40 pm
1 stop7h 40m
Bogotá El Dorado
Mon 6/29
8:40 am-10:00 pm
2 stops12h 20m
$620
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Thu 7/23
8:08 pm-1:40 pm
1 stop18h 32m
Bogotá El Dorado
Thu 7/30
11:00 am-9:02 am
2 stops21h 02m
$620
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Wed 9/2
6:11 pm-4:25 am
1 stop11h 14m
Bogotá El Dorado
Mon 9/7
11:10 pm-12:26 pm
1 stop12h 16m
$629
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Wed 9/2
6:25 am-5:50 pm
2 stops12h 25m
Bogotá El Dorado
Mon 9/7
11:00 am-9:40 am
2 stops21h 40m
$634
Showing 1-10 of 57 resultsSorted by cheapest first
Best time to book a flight from Columbus to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
CMH-MDE
CMH-BOG
CMH-LIM
CMH-EZE
CMH-UIO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to South America
CMH-0SA
CMH-MDE
CMH-BOG
CMH-LIM
CMH-EZE
How far ahead should I book a flight from Columbus Airport to South America?
To ensure you get the cheapest price possible for a flight from Columbus Airport to South America, you should look to book at least 18 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Columbus Airport to South America?
Currently, October is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $225). Flying from Columbus Airport to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 29, 2026.
Get a feel of what it's like to fly with Delta,LATAM Airlines, andUnited Airlines from Columbus Airport to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.9
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Columbus to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbus to South America by cabin class
Find flights from Columbus to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and South America flights
Browse other Columbus and South America flight options. Last updated on April 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Columbus to South America flights
Consider these flights traveling from Columbus to South America.
Top 5 airlines flying from Columbus to South America
Discover the top 5 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$244 | Average$409 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$552 | Average$800 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$552 | Average$778 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$658 | Average$923 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$962 | Average$1,449 | FlexibilityNo cancel fee | On-time69% |