$131+ Cheap flights from Columbus (CMH) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Mar 29 — Apr 51
1 adult, Economy
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Find cheap flights from Columbus to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Columbus to South AmericaExplore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.
This Travelocity deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:45 am
CMH
- CTG
1 stop7h 21m
Spirit Airlines
Wed 4/151:11 pm
CTG
- CMH
1 stop7h 41m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$296
This Cheapflightsfares deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1110:40 am
CMH
- MDE
1 stop14h 41m
Spirit Airlines
Tue 4/142:17 pm
MDE
- CMH
1 stop7h 32m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$307
This CheapOair deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:45 am
CMH
- CTG
1 stop7h 21m
Spirit Airlines
Tue 4/141:14 pm
CTG
- CMH
1 stop8h 35m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$309
This FlightHub deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
CMH
- GYE
1 stop18h 04m
Spirit Airlines
Fri 5/2211:59 pm
GYE
- CMH
1 stop13h 46m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$313
This Cheapflightsfares deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
CMH
- GYE
1 stop18h 04m
Spirit Airlines
Sat 5/911:59 pm
GYE
- CMH
1 stop10h 34m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$318
This Cheapflightsfares deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:35 pm
CMH
- MDE
1 stop12h 41m
Spirit Airlines
Sat 5/301:11 am
MDE
- CMH
1 stop9h 22m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$330
This CheapOair deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:25 am
CMH
- MDE
1 stop7h 43m
Spirit Airlines
Mon 4/201:11 am
MDE
- CMH
1 stop19h 41m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:32 pm
CMH
- CTG
2 stops17h 34m
Multiple Airlines
Tue 4/141:14 pm
CTG
- CMH
1 stop8h 35m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:03 pm
CMH
- CTG
2 stops17h 03m
Multiple Airlines
Wed 4/151:11 pm
CTG
- CMH
1 stop7h 41m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$334
This Expedia deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:45 am
CMH
- GYE
1 stop18h 19m
Spirit Airlines
Sun 4/1911:59 pm
GYE
- CMH
1 stop10h 34m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$346
This CheapOair deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:45 am
CMH
- MDE
2 stops29h 06m
Spirit Airlines
Mon 4/131:17 am
MDE
- CMH
1 stop7h 24m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$347
This Expedia deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:45 am
CMH
- MDE
1 stop8h 37m
Spirit Airlines
Wed 4/151:11 am
MDE
- CMH
1 stop9h 22m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$354
Best flights from Columbus to South AmericaDiscover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 27, 2026.
Discover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 27, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/23:48 pm
CMH
- GYE
1 stop8h 16m
Spirit Airlines
Sat 5/1611:59 pm
GYE
- CMH
1 stop10h 34m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:03 pm
CMH
- GYE
2 stops28h 01m
Multiple Airlines
Sun 4/1911:59 pm
GYE
- CMH
1 stop10h 34m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$388
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:33 pm
CMH
- CTG
2 stops17h 36m
American Airlines
Mon 5/111:25 pm
CTG
- CMH
2 stops19h 04m
American Airlines
Deal found 2/23![American Airlines logo]()
$537
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:14 pm
CMH
- CTG
1 stop19h 06m
Delta
Tue 4/282:35 pm
CTG
- CMH
1 stop9h 08m
Delta
Deal found 2/27![Delta logo]()
$572
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:01 pm
CMH
- MDE
1 stop29h 09m
United Airlines
Mon 7/209:45 am
MDE
- CMH
2 stops13h 14m
United Airlines
Deal found 2/25![United Airlines logo]()
$584
This KAYAK deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:59 pm
CMH
- LIM
2 stops25h 21m
LATAM Airlines
Tue 6/212:10 am
LIM
- CMH
2 stops23h 15m
LATAM Airlines
Deal found 2/23![LATAM Airlines logo]()
$679
This Copa Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:06 am
CMH
- LIM
2 stops17h 14m
Copa Airlines
Fri 5/291:20 pm
LIM
- CMH
2 stops18h 18m
Copa Airlines
Deal found 2/23![Copa Airlines logo]()
$682
This CheapOair deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/710:40 am
CMH
- MDE
2 stops24h 11m
Spirit Airlines
Tue 4/142:17 pm
MDE
- CMH
1 stop7h 32m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$347
This Expedia deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:45 am
CMH
- MDE
1 stop8h 37m
Spirit Airlines
Wed 4/151:11 am
MDE
- CMH
1 stop9h 22m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$354
This Air Canada deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/229:30 am
CMH
- SCL
1 stop24h 45m
Air Canada
Tue 3/247:55 pm
SCL
- CMH
1 stop26h 01m
Air Canada
Deal found 2/26![Air Canada logo]()
$793
This CheapOair deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:25 am
CMH
- MDE
1 stop7h 43m
Spirit Airlines
Tue 4/212:06 pm
MDE
- CMH
2 stops21h 06m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:45 am
CMH
- BOG
1 stop8h 26m
Multiple Airlines
Mon 3/235:05 am
BOG
- CMH
2 stops40h 44m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$457
This FlightHub deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
CMH
- GYE
1 stop18h 04m
Spirit Airlines
Fri 5/2211:59 pm
GYE
- CMH
2 stops11h 13m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:45 am
CMH
- BOG
1 stop8h 26m
Multiple Airlines
Sun 4/199:30 am
BOG
- CMH
1 stop23h 28m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$482
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1612:35 pm
CMH
- BOG
1 stop25h 33m
Spirit Airlines
Thu 4/232:07 pm
BOG
- CMH
1 stop20h 26m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:05 am
CMH
- CTG
2 stops9h 59m
American Airlines
Mon 4/203:10 pm
CTG
- CMH
2 stops20h 20m
American Airlines
Deal found 2/23![American Airlines logo]()
$561
This KAYAK deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/32:39 pm
CMH
- GIG
2 stops28h 26m
GOL
Mon 8/102:50 pm
GIG
- CMH
2 stops29h 10m
GOL
Deal found 2/26![GOL logo]()
$1,175
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
CMH
- BOG
2 stops12h 50m
Delta
Mon 5/118:40 am
BOG
- CMH
2 stops13h 41m
Delta
Deal found 2/26![Delta logo]()
$594
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:30 am
CMH
- MDE
1 stop15h 40m
United Airlines
Tue 8/119:45 am
MDE
- CMH
2 stops23h 10m
United Airlines
Deal found 2/24![United Airlines logo]()
$598
This CheapOair deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
CMH
- MDE
1 stop19h 16m
Spirit Airlines
Fri 5/291:11 am
MDE
- CMH
1 stop12h 34m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$377
This Avianca Connect deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
CMH
- GYE
2 stops19h 45m
Multiple Airlines
Fri 5/224:05 am
GYE
- CMH
2 stops16h 47m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$518
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/312:39 pm
CMH
- BOG
1 stop9h 07m
American Airlines
Mon 8/311:45 pm
BOG
- CMH
1 stop13h 04m
American Airlines
Deal found 2/23![American Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:30 am
CMH
- MDE
1 stop15h 40m
United Airlines
Wed 7/159:45 am
MDE
- CMH
2 stops21h 53m
United Airlines
Deal found 2/25![United Airlines logo]()
$598
This Copa Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/811:03 am
CMH
- LIM
2 stops15h 17m
Copa Airlines
Mon 7/207:00 am
LIM
- CMH
2 stops25h 57m
Copa Airlines
Deal found 2/26![Copa Airlines logo]()
$682
This LATAM Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2310:06 am
CMH
- UIO
1 stop9h 53m
LATAM Airlines
Wed 4/296:50 pm
UIO
- CMH
2 stops16h 01m
LATAM Airlines
Deal found 2/26![LATAM Airlines logo]()
$685
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:35 pm
CMH
- BOG
1 stop25h 33m
Spirit Airlines
Sat 5/92:07 pm
BOG
- CMH
1 stop20h 26m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$390
This Mytrip deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:05 am
CMH
- CTG
3 stops18h 05m
Multiple Airlines
Tue 4/141:14 pm
CTG
- CMH
1 stop8h 35m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$523
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 pm
CMH
- GYE
1 stop13h 55m
Delta
Tue 5/194:00 pm
GYE
- CMH
1 stop16h 24m
Delta
Deal found 2/27![Delta logo]()
$644
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/72:19 pm
CMH
- BOG
2 stops15h 35m
United Airlines
Sat 5/98:30 am
BOG
- CMH
2 stops24h 12m
United Airlines
Deal found 2/26![United Airlines logo]()
$610
This Copa Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
CMH
- LIM
2 stops17h 45m
Copa Airlines
Sat 7/117:00 am
LIM
- CMH
2 stops25h 57m
Copa Airlines
Deal found 2/24![Copa Airlines logo]()
$682
Last-minute flights from Columbus to South AmericaDiscover last-minute flight deals from Columbus to South America. Data last updated February 27, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to South America. Data last updated February 27, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:15 am
CMH
- CTG
1 stop6h 55m
Spirit Airlines
Mon 3/91:21 pm
CTG
- CMH
1 stop9h 11m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$463
This CheapOair deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:39 am
CMH
- BOG
1 stop26h 31m
Spirit Airlines
Sun 3/82:05 pm
BOG
- CMH
1 stop19h 39m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$432
This CheapOair deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:15 am
CMH
- MDE
1 stop7h 58m
Spirit Airlines
Sun 3/81:50 pm
MDE
- CMH
2 stops19h 54m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$459
This KAYAK deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:45 am
CMH
- CTG
1 stop7h 21m
Spirit Airlines
Thu 3/191:14 pm
CTG
- CMH
1 stop19h 27m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$425
This KAYAK deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:45 am
CMH
- CTG
1 stop7h 21m
Spirit Airlines
Fri 3/201:14 pm
CTG
- CMH
1 stop19h 27m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$450
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:45 am
CMH
- BOG
1 stop8h 26m
Multiple Airlines
Mon 3/235:05 am
BOG
- CMH
2 stops40h 44m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$457
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/122:51 pm
CMH
- CTG
2 stops22h 15m
Multiple Airlines
Thu 3/191:14 pm
CTG
- CMH
1 stop19h 27m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$460
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:45 am
CMH
- BOG
1 stop8h 26m
Multiple Airlines
Sun 3/222:35 pm
BOG
- CMH
2 stops42h 06m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$460
This CheapOair deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1910:40 am
CMH
- CTG
1 stop26h 26m
Spirit Airlines
Tue 3/241:14 pm
CTG
- CMH
1 stop8h 35m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$399
This CheapOair deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:45 am
CMH
- BOG
1 stop8h 26m
Spirit Airlines
Mon 3/232:10 pm
BOG
- CMH
2 stops32h 09m
Spirit Airlines
Deal found 2/24![Spirit Airlines logo]()
$434
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/205:45 am
CMH
- MDE
1 stop8h 37m
Multiple Airlines
Sat 4/251:11 am
MDE
- CMH
2 stops12h 41m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$448
This CheapOair deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/205:45 am
CMH
- MDE
1 stop8h 37m
Spirit Airlines
Sun 4/2610:51 am
MDE
- CMH
1 stop24h 21m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$454
One-way flights from Columbus to South AmericaSearch for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated February 27, 2026.
Search for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated February 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/82:51 pm
CMH
- MDE
2 stops23h 22m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:00 pm
CMH
- MDE
2 stops30h 16m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:45 am
CMH
- MDE
2 stops13h 47m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$141
This Super.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:15 am
CMH
- MDE
1 stop7h 58m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$144
This Priceline deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:35 pm
CMH
- GYE
1 stop11h 29m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$144
This Flightnetwork deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:45 am
CMH
- BOG
1 stop8h 26m
Spirit Airlines
Deal found 2/23![Spirit Airlines logo]()
$152
This Flightnetwork deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:45 am
CMH
- MDE
1 stop8h 37m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$156
This Mytrip deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:45 am
CMH
- MDE
2 stops14h 21m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:45 am
CMH
- MDE
2 stops13h 42m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:36 pm
CMH
- GYE
3 stops32h 54m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$173
This Mytrip deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:45 am
CMH
- BOG
2 stops13h 30m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/122:51 pm
CMH
- MDE
2 stops34h 30m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$178
Find flight deals from Columbus to South America
Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated February 27, 2026.
Round-trip from | $296 (Travelocity) |
|---|---|
One-way from | $131 (Kiwi.com) |
Popular in | February |
Cheapest in | October |
Average price | $1,104 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
ColumbusGuayaquil
CMH - GYE
CMHGYE
Columbus
Sat 5/2
3:48 pm-11:04 pm
1 stop8h 16m
Guayaquil Jose Joaquin de Olmedo
Sat 5/16
11:59 pm-11:33 am
1 stop10h 34m
$318
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Tue 4/7
10:40 am-9:51 am
2 stops24h 11m
Medellín Jose Maria Cordova Intl
Tue 4/14
2:17 pm-10:49 pm
1 stop7h 32m
$347
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Thu 4/9
5:45 am-1:22 pm
1 stop8h 37m
Medellín Jose Maria Cordova Intl
Wed 4/15
1:11 am-11:33 am
1 stop9h 22m
$354
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Wed 4/15
6:25 am-1:08 pm
1 stop7h 43m
Medellín Jose Maria Cordova Intl
Tue 4/21
2:06 pm-12:12 pm
2 stops21h 06m
$356
ColumbusGuayaquil
CMH - GYE
CMHGYE
Columbus
Tue 5/12
6:00 am-11:04 pm
1 stop18h 04m
Guayaquil Jose Joaquin de Olmedo
Fri 5/22
11:59 pm-12:12 pm
2 stops11h 13m
$366
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Thu 4/16
12:35 pm-1:08 pm
1 stop25h 33m
Bogotá El Dorado
Thu 4/23
2:07 pm-11:33 am
1 stop20h 26m
$375
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Wed 5/27
6:00 am-12:16 am
1 stop19h 16m
Medellín Jose Maria Cordova Intl
Fri 5/29
1:11 am-2:45 pm
1 stop12h 34m
$377
ColumbusGuayaquil
CMH - GYE
CMHGYE
Columbus
Sun 4/12
8:03 pm-11:04 pm
2 stops28h 01m
Guayaquil Jose Joaquin de Olmedo
Sun 4/19
11:59 pm-11:33 am
1 stop10h 34m
$388
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Thu 5/7
12:35 pm-1:08 pm
1 stop25h 33m
Bogotá El Dorado
Sat 5/9
2:07 pm-11:33 am
1 stop20h 26m
$390
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Thu 3/12
5:45 am-1:11 pm
1 stop8h 26m
Bogotá El Dorado
Mon 3/23
5:05 am-10:49 pm
2 stops40h 44m
$457
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Columbus to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
CMH-MDE
CMH-GYE
CMH-BOG
CMH-UIO
CMH-LIM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to South America
CMH-0SA
CMH-MDE
CMH-GYE
CMH-BOG
CMH-UIO
What is the cheapest month to book a flight from Columbus Airport to South America?
Currently, February is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $244). Flying from Columbus Airport to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 27, 2026.
Get a feel of what it's like to fly with Delta, LATAM Airlines, and American Airlines from Columbus Airport to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.9
Crew
8.5
Overall
7.9
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Comfort
7.9
Crew
8.5
Overall
7.9
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Comfort
7.9
Crew
8.5
Overall
7.9
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Comfort
7.9
Crew
8.5
Overall
7.9
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Comfort
7.9
Crew
8.5
Overall
7.9
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Comfort
7.9
Crew
8.5
Overall
7.9
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Columbus to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbus to South America by cabin class
Find flights from Columbus to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and South America flights
Browse other Columbus and South America flight options. Last updated on February 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Columbus to South America flights
Consider these flights traveling from Columbus to South America.
Top 5 airlines flying from Columbus to South America
Discover the top 5 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$244 | Average$388 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$443 | Average$726 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$552 | Average$902 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$658 | Average$880 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$744 | Average$956 | FlexibilityNo cancel fee | On-time67% |