$208+ Cheap flights from Columbus (CMH) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Oct 19 — Oct 261
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Columbus to South AmericaExplore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:08 am -
1 stop7h 07m
Thu 10/292:30 pm -
1 stop9h 14m
Deal found 9/14![Delta logo]()
$469
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am -
1 stop8h 15m
Thu 11/55:00 am -
2 stops13h 04m
Deal found 9/14![Delta logo]()
$473
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:43 pm -
2 stops20h 52m
Thu 10/291:35 pm -
1 stop7h 55m
Deal found 9/14![American Airlines logo]()
$474
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:17 pm -
1 stop19h 18m
Fri 10/231:35 pm -
2 stops19h 47m
Deal found 9/16![American Airlines logo]()
$485
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:30 am -
1 stop7h 04m
Sun 12/64:37 pm -
2 stops16h 49m
Deal found 9/17![American Airlines logo]()
$499
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:05 am -
1 stop7h 14m
Thu 11/191:50 pm -
1 stop7h 54m
Deal found 9/16![Multiple Airlines logo]()
$524
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:07 pm -
2 stops18h 28m
Sun 10/111:35 pm -
2 stops19h 47m
Deal found 9/17![American Airlines logo]()
$574
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/138:19 pm -
2 stops19h 17m
Thu 12/172:36 pm -
1 stop8h 52m
Deal found 9/14![American Airlines logo]()
$613
This Orbitz deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:10 am -
1 stop6h 35m
Sun 12/61:50 pm -
1 stop7h 45m
Deal found 9/17![JetBlue logo]()
$619
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:07 pm -
2 stops18h 28m
Mon 10/191:35 pm -
2 stops19h 47m
Deal found 9/17![American Airlines logo]()
$623
This FlightHub deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1410:33 am -
1 stop25h 27m
Fri 1/81:10 pm -
1 stop25h 46m
Deal found 9/18![Frontier logo]()
$652
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:44 pm -
3 stops24h 56m
Sat 10/2410:05 am -
3 stops31h 43m
Deal found 9/17![Multiple Airlines logo]()
$682
Best flights from Columbus to South AmericaDiscover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
Discover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:08 am -
1 stop7h 07m
Thu 10/292:30 pm -
1 stop9h 14m
Deal found 9/14![Delta logo]()
$469
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/297:45 pm -
1 stop17h 25m
Sun 1/314:00 pm -
1 stop7h 36m
Deal found 9/15![United Airlines logo]()
$469
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:36 pm -
2 stops21h 00m
Sat 11/74:37 pm -
2 stops18h 12m
Deal found 9/16![American Airlines logo]()
$474
This FlightHub deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1410:33 am -
1 stop25h 27m
Fri 1/81:10 pm -
1 stop25h 46m
Deal found 9/18![Frontier logo]()
$652
This Avianca deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:36 am -
2 stops13h 44m
Tue 11/36:00 pm -
2 stops15h 55m
Deal found 9/14![Avianca logo]()
$740
This Air Canada deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/179:30 am -
2 stops17h 45m
Sat 3/277:00 am -
2 stops37h 12m
Deal found 9/14![Air Canada logo]()
$774
This LATAM Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:07 pm -
2 stops10h 53m
Wed 11/412:55 am -
1 stop12h 21m
Deal found 9/14![LATAM Airlines logo]()
$803
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:05 am -
1 stop7h 14m
Thu 11/196:15 am -
2 stops18h 15m
Deal found 9/16![Delta logo]()
$473
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/232:17 pm -
2 stops24h 33m
Tue 1/264:00 pm -
1 stop17h 35m
Deal found 9/15![United Airlines logo]()
$474
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:56 pm -
2 stops23h 19m
Fri 11/132:15 am -
2 stops18h 19m
Deal found 9/17![Copa Airlines logo]()
$994
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/215:33 pm -
2 stops20h 02m
Mon 2/12:35 pm -
2 stops20h 05m
Deal found 9/18![American Airlines logo]()
$499
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am -
1 stop8h 15m
Thu 11/55:00 am -
2 stops13h 04m
Deal found 9/14![Delta logo]()
$473
This Trip.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:00 pm -
1 stop19h 15m
Fri 11/69:00 pm -
1 stop26h 12m
Deal found 9/15![Multiple Airlines logo]()
$1,045
This GOL deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/75:42 pm -
1 stop13h 43m
Sun 3/1411:55 pm -
1 stop20h 35m
Deal found 9/18![GOL logo]()
$1,053
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:33 am -
1 stop10h 37m
Sat 11/2110:40 am -
1 stop13h 04m
Deal found 9/16![United Airlines logo]()
$712
This LATAM Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:27 am -
2 stops11h 33m
Tue 11/1712:55 am -
1 stop9h 24m
Deal found 9/16![LATAM Airlines logo]()
$803
This Air Canada deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:30 am -
2 stops19h 20m
Mon 12/79:55 pm -
1 stop25h 17m
Deal found 9/14![Air Canada logo]()
$834
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:00 am -
2 stops13h 15m
Mon 11/27:30 am -
1 stop13h 59m
Deal found 9/14![American Airlines logo]()
$762
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:05 am -
1 stop11h 25m
Thu 11/269:00 am -
1 stop11h 37m
Deal found 9/16![Delta logo]()
$715
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:49 pm -
2 stops26h 21m
Sat 11/2110:40 am -
2 stops26h 30m
Deal found 9/16![United Airlines logo]()
$717
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:00 am -
1 stop16h 30m
Sat 10/3111:55 pm -
1 stop19h 05m
Deal found 9/14![American Airlines logo]()
$775
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:10 am -
1 stop16h 00m
Sat 11/2110:40 am -
2 stops25h 02m
Deal found 9/16![United Airlines logo]()
$717
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:05 am -
1 stop7h 20m
Mon 11/2310:45 am -
2 stops13h 45m
Deal found 9/16![Delta logo]()
$720
This FlightHub deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/79:30 am -
1 stop23h 05m
Thu 3/119:30 pm -
1 stop25h 40m
Deal found 9/18![Air Canada logo]()
$887
This Copa Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:04 am -
2 stops27h 21m
Fri 11/274:40 pm -
2 stops27h 52m
Deal found 9/14![Copa Airlines logo]()
$994
This Justfly.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/175:30 pm -
1 stop14h 25m
Sat 3/2712:10 pm -
1 stop11h 00m
Deal found 9/14![LATAM Airlines logo]()
$938
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:05 am -
2 stops12h 05m
Tue 11/243:55 pm -
1 stop8h 35m
Deal found 9/16![Delta logo]()
$720
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:15 am -
1 stop16h 20m
Tue 11/241:30 am -
1 stop14h 26m
Deal found 9/16![United Airlines logo]()
$725
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:29 am -
1 stop14h 07m
Sat 11/2112:55 am -
2 stops13h 46m
Deal found 9/15![American Airlines logo]()
$808
This LATAM Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:12 pm -
1 stop16h 03m
Sat 11/77:10 am -
2 stops18h 20m
Deal found 9/16![Multiple Airlines logo]()
$1,083
Last-minute flights from Columbus to South AmericaDiscover last-minute flight deals from Columbus to South America. Data last updated September 19, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to South America. Data last updated September 19, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:07 pm -
2 stops18h 28m
Sun 10/111:35 pm -
2 stops19h 47m
Deal found 9/17![American Airlines logo]()
$574
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:07 pm -
2 stops18h 28m
Mon 10/121:35 pm -
2 stops19h 47m
Deal found 9/16![American Airlines logo]()
$698
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:08 am -
1 stop7h 07m
Tue 10/135:25 pm -
2 stops23h 10m
Deal found 9/16![LATAM Airlines logo]()
$729
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:07 pm -
2 stops18h 28m
Mon 10/191:35 pm -
2 stops19h 47m
Deal found 9/17![American Airlines logo]()
$623
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:17 pm -
1 stop19h 18m
Fri 10/231:35 pm -
2 stops19h 47m
Deal found 9/16![American Airlines logo]()
$485
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:44 pm -
3 stops24h 56m
Sat 10/2410:05 am -
3 stops31h 43m
Deal found 9/17![Multiple Airlines logo]()
$682
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:08 am -
1 stop7h 07m
Thu 10/292:30 pm -
1 stop9h 14m
Deal found 9/14![Delta logo]()
$469
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:42 pm -
2 stops19h 53m
Thu 10/291:35 pm -
2 stops19h 08m
Deal found 9/14![American Airlines logo]()
$474
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am -
1 stop8h 15m
Thu 11/55:00 am -
2 stops13h 04m
Deal found 9/14![Delta logo]()
$473
This lastminute.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:56 pm -
2 stops20h 39m
Thu 11/55:00 am -
2 stops13h 04m
Deal found 9/14![Multiple Airlines logo]()
$732
This Avianca deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:36 am -
2 stops13h 44m
Tue 11/36:00 pm -
2 stops15h 55m
Deal found 9/14![Avianca logo]()
$740
This Trip.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:10 am -
1 stop30h 05m
Sat 11/77:40 am -
1 stop30h 37m
Deal found 9/16![Avianca logo]()
$738
One-way flights from Columbus to South AmericaSearch for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
Search for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
This LATAM Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
1 stop7h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![LATAM Airlines logo]()
$208
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:19 pm -
1 stop20h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Delta logo]()
$219
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:07 pm -
2 stops18h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:44 pm -
3 stops46h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:44 pm -
3 stops28h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:44 pm -
3 stops37h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:22 pm -
3 stops54h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am -
2 stops37h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Delta logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:44 pm -
3 stops37h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:00 am -
2 stops8h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$308
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/159:30 am -
2 stops26h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:13 pm -
3 stops25h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$341
Find flight deals from Columbus to South America
Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated September 19, 2026.
Round-trip from | $469 (United Airlines) |
|---|---|
One-way from | $208 (American Airlines) |
Popular in | February |
Cheapest in | April |
Average price | $750 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Mon 2/1
5:55 pm-2:50 pm
2 stops20h 55m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$208
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Mon 2/1
6:00 am-3:41 pm
1 stop9h 41m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$208
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Fri 10/16
5:19 pm-1:15 pm
1 stop20h 56m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$219
ColumbusBogotá
CMH Columbus - BOG Bogotá El Dorado
CMHBOG
Columbus
Sun 10/25
7:44 pm-5:30 pm
3 stops46h 46m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$239
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Thu 10/15
7:07 pm-12:35 pm
2 stops18h 28m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$239
ColumbusBogotá
CMH Columbus - BOG Bogotá El Dorado
CMHBOG
Columbus
Tue 10/20
7:44 pm-10:55 pm
3 stops28h 11m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$253
ColumbusBogotá
CMH Columbus - BOG Bogotá El Dorado
CMHBOG
Columbus
Sat 10/24
7:22 pm-12:40 am
3 stops54h 18m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$261
ColumbusCartagena
CMH Columbus - CTG Cartagena Rafael Nunez
CMHCTG
Columbus
Sat 10/17
6:00 am-6:30 pm
2 stops37h 30m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$270
ColumbusMedellín
CMH Columbus - MDE Medellín Jose Maria Cordova Intl
CMHMDE
Columbus
Thu 10/15
7:44 pm-8:15 am
3 stops37h 31m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$295
ColumbusMedellín
CMH Columbus - MDE Medellín Jose Maria Cordova Intl
CMHMDE
Columbus
Tue 11/3
10:36 am-11:20 pm
2 stops12h 44m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$354
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Columbus to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
CMH-CTG
CMH-BOG
CMH-MDE
CMH-LIM
CMH-GRU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to South America
CMH-0SA
CMH-CTG
CMH-BOG
CMH-MDE
CMH-LIM
What is the cheapest month to book a flight from Columbus Airport to South America?
Currently, March is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $649). Flying from Columbus Airport to South America in December is currently the most expensive (average of $1,197). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 19, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from Columbus Airport to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Columbus to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbus to South America by cabin class
Find flights from Columbus to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and South America flights
Browse other Columbus and South America flight options. Last updated on September 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Columbus to South America flights
Consider these flights traveling from Columbus to South America.
Top 4 airlines flying from Columbus to South America
Discover the top 4 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$491 | Average$810 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$563 | Average$1,154 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$575 | Average$883 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$614 | Average$898 | FlexibilityNo cancel fee | On-time81% |