$132+ Cheap flights from Columbus (CMH) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Apr 25 — May 21
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to South America with Cheapflights
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Cheapest flights from Columbus to South AmericaExplore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:00 am
CMH
- BOG
1 stop8h 12m
Multiple Airlines
Sat 5/162:07 pm
BOG
- CMH
2 stops26h 03m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$371
This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:05 am
CMH
- MDE
1 stop7h 47m
Spirit Airlines
Mon 4/131:17 am
MDE
- CMH
1 stop7h 24m
Spirit Airlines
Deal found 3/24![Spirit Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
CMH
- MDE
1 stop8h 08m
Multiple Airlines
Mon 5/42:06 pm
MDE
- CMH
2 stops26h 04m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$375
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:00 am
CMH
- BOG
1 stop8h 12m
Spirit Airlines
Mon 4/272:07 pm
BOG
- CMH
2 stops28h 28m
Spirit Airlines
Deal found 3/22![Spirit Airlines logo]()
$381
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/810:40 am
CMH
- BOG
2 stops26h 15m
Spirit Airlines
Sat 4/112:10 pm
BOG
- CMH
1 stop18h 31m
Spirit Airlines
Deal found 3/25![Spirit Airlines logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:00 am
CMH
- MDE
1 stop8h 08m
Multiple Airlines
Sun 5/32:06 pm
MDE
- CMH
2 stops19h 59m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$383
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:45 am
CMH
- MDE
1 stop19h 36m
Multiple Airlines
Tue 4/148:15 pm
MDE
- CMH
2 stops45h 00m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$386
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
CMH
- MDE
1 stop8h 08m
Multiple Airlines
Sun 5/32:06 pm
MDE
- CMH
2 stops19h 59m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$387
This Expedia deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
CMH
- MDE
1 stop8h 08m
Spirit Airlines
Thu 5/142:06 pm
MDE
- CMH
1 stop7h 35m
Spirit Airlines
Deal found 3/23![Spirit Airlines logo]()
$394
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
CMH
- BOG
1 stop8h 12m
Multiple Airlines
Mon 5/112:07 pm
BOG
- CMH
2 stops26h 03m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$399
This Cheapflightsfares deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
CMH
- MDE
1 stop8h 08m
Spirit Airlines
Thu 5/212:06 pm
MDE
- CMH
1 stop7h 35m
Spirit Airlines
Deal found 3/23![Spirit Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:00 am
CMH
- MDE
1 stop8h 08m
Multiple Airlines
Sat 4/252:06 pm
MDE
- CMH
2 stops23h 46m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$409
Best flights from Columbus to South AmericaDiscover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
Discover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:05 am
CMH
- MDE
1 stop7h 47m
Spirit Airlines
Mon 4/131:17 am
MDE
- CMH
1 stop7h 24m
Spirit Airlines
Deal found 3/24![Spirit Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:45 am
CMH
- MDE
1 stop19h 36m
Multiple Airlines
Tue 4/148:15 pm
MDE
- CMH
2 stops45h 00m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$386
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:00 am
CMH
- BOG
1 stop16h 17m
American Airlines
Tue 5/2612:20 pm
BOG
- CMH
1 stop9h 17m
American Airlines
Deal found 3/21![American Airlines logo]()
$609
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:38 am
CMH
- BOG
2 stops19h 16m
United Airlines
Sat 5/2312:14 am
BOG
- CMH
1 stop9h 48m
United Airlines
Deal found 3/22![United Airlines logo]()
$624
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:00 pm
CMH
- CTG
2 stops29h 10m
Delta
Sat 4/252:35 pm
CTG
- CMH
1 stop28h 57m
Delta
Deal found 3/21![Delta logo]()
$635
This KAYAK deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1610:10 am
CMH
- UIO
1 stop9h 49m
LATAM Airlines
Sun 5/2412:59 am
UIO
- CMH
1 stop21h 22m
LATAM Airlines
Deal found 3/23![LATAM Airlines logo]()
$695
This Copa Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/211:03 am
CMH
- LIM
2 stops15h 17m
Copa Airlines
Wed 7/154:40 pm
LIM
- CMH
2 stops16h 17m
Copa Airlines
Deal found 3/25![Copa Airlines logo]()
$732
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
CMH
- MDE
1 stop8h 08m
Multiple Airlines
Sun 5/32:06 pm
MDE
- CMH
2 stops19h 59m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$387
This Mytrip deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
CMH
- MDE
1 stop8h 08m
Spirit Airlines
Thu 5/142:06 pm
MDE
- CMH
1 stop7h 35m
Spirit Airlines
Deal found 3/23![Spirit Airlines logo]()
$394
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
CMH
- BOG
1 stop8h 12m
Multiple Airlines
Mon 5/112:07 pm
BOG
- CMH
2 stops26h 03m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$400
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:27 pm
CMH
- MDE
1 stop21h 33m
Spirit Airlines
Tue 4/211:55 pm
MDE
- CMH
1 stop28h 40m
Spirit Airlines
Deal found 3/21![Spirit Airlines logo]()
$454
This Air Canada deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/62:15 pm
CMH
- EZE
3 stops23h 15m
Air Canada
Mon 9/144:35 pm
EZE
- CMH
3 stops47h 47m
Air Canada
Deal found 3/25![Air Canada logo]()
$1,120
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:28 pm
CMH
- MDE
2 stops19h 32m
Multiple Airlines
Mon 6/81:55 pm
MDE
- CMH
1 stop25h 35m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$487
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:00 am
CMH
- MDE
1 stop8h 08m
Spirit Airlines
Thu 5/282:06 pm
MDE
- CMH
1 stop7h 35m
Spirit Airlines
Deal found 3/21![Spirit Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/411:32 am
CMH
- BOG
1 stop11h 58m
American Airlines
Mon 5/116:30 am
BOG
- CMH
1 stop17h 29m
American Airlines
Deal found 3/21![American Airlines logo]()
$610
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:40 pm
CMH
- BOG
1 stop9h 20m
United Airlines
Sun 5/178:30 am
BOG
- CMH
1 stop12h 41m
United Airlines
Deal found 3/24![United Airlines logo]()
$625
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:39 pm
CMH
- MDE
1 stop19h 21m
Spirit Airlines
Mon 6/81:55 pm
MDE
- CMH
1 stop26h 49m
Spirit Airlines
Deal found 3/20![Spirit Airlines logo]()
$499
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:00 am
CMH
- EZE
2 stops24h 00m
Azul
Sat 8/159:00 pm
EZE
- CMH
2 stops27h 59m
Azul
Deal found 3/22![Azul logo]()
$1,355
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:33 pm
CMH
- CTG
2 stops17h 36m
American Airlines
Sun 5/33:10 pm
CTG
- CMH
2 stops18h 19m
American Airlines
Deal found 3/24![American Airlines logo]()
$619
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/258:05 am
CMH
- UIO
2 stops21h 38m
Delta
Thu 6/46:50 pm
UIO
- CMH
2 stops17h 35m
Delta
Deal found 3/22![Delta logo]()
$681
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:00 am
CMH
- BOG
1 stop8h 12m
Multiple Airlines
Mon 4/274:05 pm
BOG
- CMH
1 stop26h 30m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$531
This Copa Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/211:03 am
CMH
- LIM
2 stops15h 17m
Copa Airlines
Thu 7/164:40 pm
LIM
- CMH
2 stops16h 17m
Copa Airlines
Deal found 3/25![Copa Airlines logo]()
$732
This FlightHub deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/72:45 pm
CMH
- LIM
2 stops15h 15m
LATAM Airlines
Tue 6/1612:05 pm
LIM
- CMH
1 stop11h 49m
LATAM Airlines
Deal found 3/23![LATAM Airlines logo]()
$751
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:01 pm
CMH
- UIO
1 stop12h 59m
United Airlines
Sun 8/3012:35 am
UIO
- CMH
1 stop9h 27m
United Airlines
Deal found 3/22![United Airlines logo]()
$686
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:45 am
CMH
- CTG
1 stop7h 21m
Spirit Airlines
Sun 4/191:11 pm
CTG
- CMH
1 stop8h 21m
Spirit Airlines
Deal found 3/21![Spirit Airlines logo]()
$541
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:48 pm
CMH
- MDE
1 stop17h 12m
Multiple Airlines
Thu 5/2810:45 pm
MDE
- CMH
2 stops46h 56m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$546
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:08 am
CMH
- GYE
1 stop18h 29m
American Airlines
Thu 7/302:37 pm
GYE
- CMH
1 stop21h 20m
American Airlines
Deal found 3/22![American Airlines logo]()
$661
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2310:06 am
CMH
- UIO
1 stop9h 53m
Delta
Mon 4/2712:59 am
UIO
- CMH
1 stop16h 30m
Delta
Deal found 3/26![Delta logo]()
$732
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:49 am
CMH
- CTG
2 stops14h 11m
United Airlines
Mon 4/206:20 am
CTG
- CMH
2 stops14h 39m
United Airlines
Deal found 3/22![United Airlines logo]()
$692
This Copa Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/911:03 am
CMH
- LIM
2 stops15h 17m
Copa Airlines
Mon 7/204:40 pm
LIM
- CMH
2 stops16h 17m
Copa Airlines
Deal found 3/21![Copa Airlines logo]()
$768
Last-minute flights from Columbus to South AmericaDiscover last-minute flight deals from Columbus to South America. Data last updated March 26, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to South America. Data last updated March 26, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:05 am
CMH
- MDE
1 stop7h 47m
Spirit Airlines
Mon 4/131:17 am
MDE
- CMH
1 stop7h 24m
Spirit Airlines
Deal found 3/24![Spirit Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:45 am
CMH
- MDE
1 stop19h 36m
Multiple Airlines
Tue 4/148:15 pm
MDE
- CMH
2 stops45h 00m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$386
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/810:40 am
CMH
- BOG
2 stops26h 15m
Spirit Airlines
Sat 4/112:10 pm
BOG
- CMH
1 stop18h 31m
Spirit Airlines
Deal found 3/25![Spirit Airlines logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:45 am
CMH
- BOG
1 stop8h 26m
Multiple Airlines
Thu 4/302:07 pm
BOG
- CMH
2 stops26h 33m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$433
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:40 am
CMH
- CTG
1 stop26h 26m
Multiple Airlines
Sun 4/191:11 pm
CTG
- CMH
2 stops21h 04m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$476
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:00 am
CMH
- BOG
1 stop8h 12m
Spirit Airlines
Mon 4/272:07 pm
BOG
- CMH
2 stops28h 28m
Spirit Airlines
Deal found 3/22![Spirit Airlines logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/233:47 pm
CMH
- MDE
1 stop22h 21m
Multiple Airlines
Tue 4/286:52 pm
MDE
- CMH
2 stops26h 40m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$427
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/233:47 pm
CMH
- MDE
1 stop22h 21m
Multiple Airlines
Sat 4/252:06 pm
MDE
- CMH
1 stop27h 09m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$432
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:00 am
CMH
- MDE
1 stop8h 08m
Multiple Airlines
Sun 5/32:06 pm
MDE
- CMH
2 stops19h 59m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$383
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:00 am
CMH
- MDE
1 stop8h 08m
Multiple Airlines
Sat 4/252:06 pm
MDE
- CMH
2 stops23h 46m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
CMH
- MDE
1 stop8h 08m
Multiple Airlines
Mon 5/42:06 pm
MDE
- CMH
2 stops26h 04m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
CMH
- MDE
1 stop8h 08m
Multiple Airlines
Sun 5/32:06 pm
MDE
- CMH
2 stops19h 59m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$387
One-way flights from Columbus to South AmericaSearch for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
Search for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
This Super.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:00 am
CMH
- BOG
1 stop8h 12m
Spirit Airlines
Deal found 3/22![Spirit Airlines logo]()
$132
This Mytrip deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:45 am
CMH
- MDE
1 stop8h 37m
Spirit Airlines
Deal found 3/23![Spirit Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
CMH
- MDE
1 stop8h 08m
Spirit Airlines
Deal found 3/22![Spirit Airlines logo]()
$172
This Super.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:45 am
CMH
- BOG
1 stop8h 26m
Spirit Airlines
Deal found 3/23![Spirit Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:45 am
CMH
- BOG
1 stop8h 26m
Spirit Airlines
Deal found 3/22![Spirit Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:28 pm
CMH
- MDE
2 stops19h 32m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$199
This Spirit deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:21 pm
CMH
- MDE
1 stop16h 39m
Spirit Airlines
Deal found 3/25![Spirit Airlines logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:00 pm
CMH
- CTG
3 stops25h 02m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:35 pm
CMH
- MDE
2 stops19h 33m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$211
This Mytrip deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:45 am
CMH
- BOG
3 stops18h 15m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/299:15 am
CMH
- BOG
1 stop28h 56m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$230
This Spirit deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:40 am
CMH
- MDE
1 stop14h 41m
Spirit Airlines
Deal found 3/25![Spirit Airlines logo]()
$264
Find flight deals from Columbus to South America
Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated March 26, 2026.
Round-trip from | $371 (Kiwi.com) |
|---|---|
One-way from | $132 (Super.com) |
Popular in | February |
Cheapest in | October |
Average price | $436 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Columbus Airport to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Tue 4/7
6:05 am-12:52 pm
1 stop7h 47m
Medellín Jose Maria Cordova Intl
Mon 4/13
1:17 am-9:41 am
1 stop7h 24m
$374
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Tue 4/7
5:45 am-12:21 am
1 stop19h 36m
Medellín Jose Maria Cordova Intl
Tue 4/14
8:15 pm-6:15 pm
2 stops45h 00m
$386
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Thu 4/30
6:00 am-1:08 pm
1 stop8h 08m
Medellín Jose Maria Cordova Intl
Sun 5/3
2:06 pm-11:05 am
2 stops19h 59m
$387
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Thu 5/7
6:00 am-1:08 pm
1 stop8h 08m
Medellín Jose Maria Cordova Intl
Thu 5/14
2:06 pm-10:41 pm
1 stop7h 35m
$394
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Mon 5/4
6:00 am-1:12 pm
1 stop8h 12m
Bogotá El Dorado
Mon 5/11
2:07 pm-5:10 pm
2 stops26h 03m
$400
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Wed 4/15
4:27 pm-1:00 pm
1 stop21h 33m
Medellín Jose Maria Cordova Intl
Tue 4/21
1:55 pm-7:35 pm
1 stop28h 40m
$454
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Mon 6/1
6:28 pm-1:00 pm
2 stops19h 32m
Medellín Jose Maria Cordova Intl
Mon 6/8
1:55 pm-4:30 pm
1 stop25h 35m
$487
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Fri 5/22
6:00 am-1:08 pm
1 stop8h 08m
Medellín Jose Maria Cordova Intl
Thu 5/28
2:06 pm-10:41 pm
1 stop7h 35m
$489
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Mon 6/1
6:39 pm-1:00 pm
1 stop19h 21m
Medellín Jose Maria Cordova Intl
Mon 6/8
1:55 pm-5:44 pm
1 stop26h 49m
$499
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Mon 4/20
6:00 am-1:12 pm
1 stop8h 12m
Bogotá El Dorado
Mon 4/27
4:05 pm-7:35 pm
1 stop26h 30m
$531
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Columbus to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
CMH-MDE
CMH-BOG
CMH-CTG
CMH-UIO
CMH-LIM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus Airport to South America
CMH-0SA
CMH-MDE
CMH-BOG
CMH-CTG
CMH-UIO
What is the cheapest month to book a flight from Columbus Airport to South America?
Currently, February is the cheapest month in which you can book a flight from Columbus Airport to South America (average of $243). Flying from Columbus Airport to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated March 26, 2026.
Get a feel of what it's like to fly with Delta,LATAM Airlines, andAmerican Airlines from Columbus Airport to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Columbus to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbus to South America by cabin class
Find flights from Columbus to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbus and South America flights
Browse other Columbus and South America flight options. Last updated on March 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Columbus to South America flights
Consider these flights traveling from Columbus to South America.
Top 6 airlines flying from Columbus to South America
Discover the top 6 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$244 | Average$409 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$552 | Average$768 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$552 | Average$783 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$658 | Average$916 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$744 | Average$956 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$962 | Average$1,449 | FlexibilityNo cancel fee | On-time69% |