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South America

$138+ Cheap flights from Indianapolis (IND) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
IND — BOG
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Indianapolis to South America

Keep the following information in mind while searching for Indianapolis to South America flight deals. Data was last updated July 30, 2025.

Round-trip from

$266
(Expedia)

One-way from

$138
(Cheapflightsfares)

Popular in

April

Cheapest in

May

Average price

$965
From Indianapolis to South America
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One-way flight from Indianapolis to South America
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Highest demand for flights based on searches. 29% potential increase in price ($548 potential increase over avg. RT price).
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Cheapest flight prices on average. 25% potential price decrease ($265 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Indianapolis to South America

Cheapest flights from Indianapolis to South America
Explore the most affordable flight options available from Indianapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This Expedia deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:24 pmIND - MDE
1 stop7h 01mSpirit Airlines
Wed 9/171:24 amMDE - IND
1 stop8h 29mSpirit Airlines
Deal found 7/28$228
This Cheapflightsfares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:35 amIND - CTG
1 stop6h 33mSpirit Airlines
Tue 11/112:16 pmCTG - IND
1 stop8h 40mSpirit Airlines
Deal found 7/29$272
This SmartFares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/125:30 amIND - BOG
1 stop7h 30mSpirit Airlines
Fri 9/1912:55 pmBOG - IND
1 stop9h 16mSpirit Airlines
Deal found 7/29$289
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/217:50 pmIND - MDE
1 stop29h 04mMultiple Airlines
Wed 8/2712:49 amMDE - IND
1 stop15h 20mMultiple Airlines
Deal found 7/30$332
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/127:43 pmIND - CTG
1 stop17h 40mMultiple Airlines
Fri 9/199:59 pmCTG - IND
2 stops11h 54mMultiple Airlines
Deal found 7/29$369
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1312:20 pmIND - BOG
2 stops23h 45mMultiple Airlines
Sat 9/202:05 pmBOG - IND
2 stops19h 10mMultiple Airlines
Deal found 7/30$382
This Avianca Connect deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:30 amIND - UIO
2 stops20h 04mMultiple Airlines
Fri 9/191:40 amUIO - IND
2 stops20h 31mMultiple Airlines
Deal found 7/30$488
This Avianca deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/910:05 amIND - BOG
2 stops16h 50mAvianca
Tue 9/2311:00 pmBOG - IND
1 stop10h 34mAvianca
Deal found 7/30$509
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/227:50 pmIND - LIM
1 stop25h 20mSpirit Airlines
Sun 9/79:00 amLIM - IND
1 stop24h 53mSpirit Airlines
Deal found 7/30$539
This Avianca Connect deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/45:30 amIND - LIM
2 stops20h 20mMultiple Airlines
Fri 11/142:55 amLIM - IND
2 stops20h 01mMultiple Airlines
Deal found 7/30$547
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/66:51 pmIND - BOG
2 stops17h 04mDelta
Sun 10/121:35 amBOG - IND
2 stops18h 40mDelta
Deal found 7/29$561
This Trip.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/45:30 amIND - GRU
2 stops23h 05mMultiple Airlines
Tue 9/94:10 amGRU - IND
2 stops16h 47mMultiple Airlines
Deal found 7/30$562

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Indianapolis to South America that are best for you.

Fly from

Indianapolis

Fly to

South America

Route

Depart

Return

Price

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

Tue 9/2

3:05 pm-11:54 pm

1 stop9h 49m

Medellín Jose Maria Cordova Intl

Sun 9/14

1:24 am-10:53 am

1 stop8h 29m

$266

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

Thu 11/6

6:35 am-1:08 pm

1 stop6h 33m

Cartagena Rafael Nunez

Tue 11/11

2:16 pm-10:56 pm

1 stop8h 40m

$272

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Fri 9/12

5:30 am-12:00 pm

1 stop7h 30m

Bogotá El Dorado

Fri 9/19

12:55 pm-11:11 pm

1 stop9h 16m

$289

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

Thu 8/21

7:50 pm-11:54 pm

1 stop29h 04m

Medellín Jose Maria Cordova Intl

Wed 8/27

12:49 am-5:09 pm

1 stop15h 20m

$332

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

Fri 9/12

7:43 pm-12:23 pm

1 stop17h 40m

Cartagena Rafael Nunez

Fri 9/19

9:59 pm-10:53 am

2 stops11h 54m

$369

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Sat 9/13

12:20 pm-11:05 am

2 stops23h 45m

Bogotá El Dorado

Sat 9/20

2:05 pm-10:15 am

2 stops19h 10m

$382

IndianapolisQuito

IND - UIO

INDUIO

Indianapolis

Sat 9/13

5:30 am-12:34 am

2 stops20h 04m

Quito Mariscal Sucr

Fri 9/19

1:40 am-11:11 pm

2 stops20h 31m

$488

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Tue 9/9

10:05 am-1:55 am

2 stops16h 50m

Bogotá El Dorado

Tue 9/23

11:00 pm-10:34 am

1 stop10h 34m

$509

IndianapolisLima

IND - LIM

INDLIM

Indianapolis

Fri 8/22

7:50 pm-8:10 pm

1 stop25h 20m

Lima J Chavez Intl

Sun 9/7

9:00 am-10:53 am

1 stop24h 53m

$539

IndianapolisLima

IND - LIM

INDLIM

Indianapolis

Tue 11/4

5:30 am-1:50 am

2 stops20h 20m

Lima J Chavez Intl

Fri 11/14

2:55 am-10:56 pm

2 stops20h 01m

$547

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 59 results
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Best time to book a flight from Indianapolis to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to South America

What is the cheapest month to book a flight from Indianapolis to South America?

Currently, May is the cheapest month in which you can book a flight from Indianapolis to South America (average of $359). Flying from Indianapolis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to SA?

Find hourly flight availability from Indianapolis to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

When flying from Indianapolis to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 30, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and Copa Airlines from Indianapolis to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,822 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,493 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to South America?

    If you book a flight to South America from Indianapolis, you will be flying from Indianapolis, which is the city’s only airport. Indianapolis (IND) is located 8.3 mi from the center of Indianapolis.

  • What are the cheapest airlines to fly from Indianapolis to South America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $138. Avianca flights start at $287 while deals on Delta start at $313 one-way.

  • What are the most popular routes from Indianapolis to South America?

    The most popular flight routes from Indianapolis to South America are Indianapolis - Lima J Chavez Intl, Indianapolis - Cartagena Rafael Nunez and Indianapolis - Buenos Aires Ministro Pistarini.

  • Can I find deals for flights from Indianapolis to South America that include hotel bookings?

    Yes. In addition to deals on Indianapolis to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to South America.

  • Can I find deals for business class flights from Indianapolis to South America?

    Yes. Cheapflights offers flight deals from Indianapolis to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to South America?

    Currently, May is the cheapest month in which you can book a flight from Indianapolis to South America (average of $359). Flying from Indianapolis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indianapolis to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Indianapolis to South America

Discover the top 5 airlines that operate flights from Indianapolis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$288Average$632FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$412Average$941FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$419Average$1,085FlexibilityNo cancel feeOn-time81%
DeltaCheapest$426Average$943FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$687Average$1,127FlexibilityNo cancel feeOn-time69%

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