South America

$134+ Cheap flights from Indianapolis (IND) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.
IND — BOG
jun. 17 — jun. 241
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Cheap flight deals from Indianapolis to South America

Keep the following information in mind while searching for Indianapolis to South America flight deals. Data was last updated junio 12, 2025.

Round-trip from

$246
(Cheapflightsfares)

One-way from

$134
(Mytrip)

Popular in

April

Cheapest in

May

Average price

$1,077
From Indianapolis to South America
One-way flight from Indianapolis to South America
Highest demand for flights based on searches. 25% potential increase in price ($485 potential increase over avg. RT price).
Cheapest flight prices on average. 20% potential price decrease ($235 potential savings vs. average RT price).
Average for round-trip flights in June 2025

Find flight deals from Indianapolis to South America

Cheapest flights from Indianapolis to South America
Explore the most affordable flight options available from Indianapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 7/136:30 amIND - CTG
1 stop6h 45mSpirit Airlines
sáb. 7/191:28 pmCTG - IND
1 stop8h 40mSpirit Airlines
Deal found 6/11$246
This FlightHub deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/56:30 amIND - BOG
1 stop7h 35mSpirit Airlines
mié. 8/202:03 pmBOG - IND
1 stop18h 43mSpirit Airlines
Deal found 6/9$313
This FlightHub deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/46:30 amIND - MDE
1 stop7h 42mSpirit Airlines
mié. 8/202:14 pmMDE - IND
1 stop18h 32mSpirit Airlines
Deal found 6/9$331
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/44:16 pmIND - BOG
1 stop21h 49mMultiple Airlines
jue. 8/212:03 pmBOG - IND
1 stop18h 43mMultiple Airlines
Deal found 6/9$341
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/34:02 pmIND - MDE
1 stop22h 10mMultiple Airlines
vie. 8/222:14 pmMDE - IND
1 stop18h 32mMultiple Airlines
Deal found 6/9$354
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/73:08 pmIND - CTG
1 stop22h 07mMultiple Airlines
jue. 8/141:14 pmCTG - IND
1 stop19h 32mMultiple Airlines
Deal found 6/9$382
This CheapOair deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/196:30 amIND - CLO
1 stop7h 50mSpirit Airlines
dom. 7/272:15 pmCLO - IND
2 stops42h 05mSpirit Airlines
Deal found 6/12$459
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/254:16 pmIND - CLO
1 stop22h 04mMultiple Airlines
vie. 8/12:15 pmCLO - IND
1 stop20h 56mMultiple Airlines
Deal found 6/10$475
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/216:00 amIND - CTG
1 stop7h 50mDelta
jue. 8/282:05 pmCTG - IND
1 stop9h 03mDelta
Deal found 6/12$523
This Avianca Connect deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/256:27 amIND - LIM
2 stops21h 58mMultiple Airlines
lun. 6/301:40 amLIM - IND
2 stops22h 19mMultiple Airlines
Deal found 6/11$527
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/216:37 amIND - CTG
1 stop8h 27mAmerican Airlines
jue. 8/283:10 pmCTG - IND
2 stops18h 10mAmerican Airlines
Deal found 6/12$527
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/225:45 pmIND - LIM
1 stop27h 58mSpirit Airlines
dom. 8/249:00 amLIM - IND
1 stop23h 46mSpirit Airlines
Deal found 6/10$539

Cheapflights Fare Finder

Customize your flight search to find flights from Indianapolis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Indianapolis to South America that are best for you.

Fly from

Indianapolis

Fly to

South America

Route

Depart

Return

Price

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

dom. 7/13

6:30 am-12:15 pm

1 stop6h 45m

Cartagena Rafael Nunez

sáb. 7/19

1:28 pm-11:08 pm

1 stop8h 40m

$246

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

mar. 8/5

6:30 am-1:05 pm

1 stop7h 35m

Bogotá El Dorado

mié. 8/20

2:03 pm-9:46 am

1 stop18h 43m

$313

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

lun. 8/4

6:30 am-1:12 pm

1 stop7h 42m

Medellín Jose Maria Cordova Intl

mié. 8/20

2:14 pm-9:46 am

1 stop18h 32m

$331

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

lun. 8/4

4:16 pm-1:05 pm

1 stop21h 49m

Bogotá El Dorado

jue. 8/21

2:03 pm-9:46 am

1 stop18h 43m

$341

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

dom. 8/3

4:02 pm-1:12 pm

1 stop22h 10m

Medellín Jose Maria Cordova Intl

vie. 8/22

2:14 pm-9:46 am

1 stop18h 32m

$354

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

jue. 8/7

3:08 pm-12:15 pm

1 stop22h 07m

Cartagena Rafael Nunez

jue. 8/14

1:14 pm-9:46 am

1 stop19h 32m

$382

IndianapolisCali

IND - CLO

INDCLO

Indianapolis

sáb. 7/19

6:30 am-1:20 pm

1 stop7h 50m

Cali Alfonso B. Aragon Intl

dom. 7/27

2:15 pm-9:20 am

2 stops42h 05m

$459

IndianapolisCali

IND - CLO

INDCLO

Indianapolis

vie. 7/25

4:16 pm-1:20 pm

1 stop22h 04m

Cali Alfonso B. Aragon Intl

vie. 8/1

2:15 pm-12:11 pm

1 stop20h 56m

$475

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

jue. 8/21

6:00 am-12:50 pm

1 stop7h 50m

Cartagena Rafael Nunez

jue. 8/28

2:05 pm-12:08 am

1 stop9h 03m

$523

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

jue. 8/21

6:37 am-2:04 pm

1 stop8h 27m

Cartagena Rafael Nunez

jue. 8/28

3:10 pm-10:20 am

2 stops18h 10m

$527

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 52 results
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Best time to book a flight from Indianapolis to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to South America

What is the cheapest month to book a flight from Indianapolis to South America?

Currently, May is the cheapest month in which you can book a flight from Indianapolis to South America (average of $359). Flying from Indianapolis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to SA?

Find hourly flight availability from Indianapolis to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

When flying from Indianapolis to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated junio 12, 2025.
8.0
Very good

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Indianapolis to South America?

    If you book a flight to South America from Indianapolis, you will be flying from Indianapolis, which is the city’s only airport. Indianapolis (IND) is located 8.3 mi from the center of Indianapolis.

  • What are the cheapest airlines to fly from Indianapolis to South America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $147. LATAM Airlines flights start at $192 while deals on Avianca start at $247 one-way.

  • What are the most popular routes from Indianapolis to South America?

  • Can I find deals for flights from Indianapolis to South America that include hotel bookings?

    Yes. In addition to deals on Indianapolis to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to South America.

  • Can I find deals for business class flights from Indianapolis to South America?

    Yes. Cheapflights offers flight deals from Indianapolis to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to South America?

    Currently, May is the cheapest month in which you can book a flight from Indianapolis to South America (average of $359). Flying from Indianapolis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Indianapolis to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Indianapolis to South America

Discover the top 6 airlines that operate flights from Indianapolis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$288Average$680FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$409Average$1,113FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$420Average$659FlexibilityNo cancel feeOn-time70%
DeltaCheapest$426Average$940FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$489Average$977FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$538Average$981FlexibilityNo cancel feeOn-time69%

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