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South America

$83+ Cheap flights from Indianapolis (IND) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
IND — BOG
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Indianapolis to South America

Keep the following information in mind while searching for Indianapolis to South America flight deals. Data was last updated septiembre 11, 2025.

Round-trip from

$278
(Cheapflightsfares)

One-way from

$83
(Cheapflightsfares)

Popular in

April

Cheapest in

May
From Indianapolis to South America
Search Deals
One-way flight from Indianapolis to South America
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Highest demand for flights based on searches. 29% potential increase in price ($554 potential increase over avg. RT price).
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Cheapest flight prices on average. 25% potential price decrease ($266 potential savings vs. average RT price).
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Find flight deals from Indianapolis to South America

Cheapest flights from Indianapolis to South America
Explore the most affordable flight options available from Indianapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/156:35 amIND - CTG
1 stop6h 33mSpirit Airlines
jue. 11/202:16 pmCTG - IND
1 stop8h 40mSpirit Airlines
Deal found 9/10$278
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/106:35 amIND - MDE
1 stop7h 41mSpirit Airlines
mié. 11/193:11 pmMDE - IND
1 stop7h 45mSpirit Airlines
Deal found 9/11$280
This Cheapflightsfares deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/106:35 amIND - MDE
1 stop11h 29mSpirit Airlines
lun. 11/173:11 pmMDE - IND
1 stop7h 45mSpirit Airlines
Deal found 9/9$304
This Expedia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/268:16 pmIND - CLO
1 stop18h 07mSpirit Airlines
dom. 11/23:20 pmCLO - IND
1 stop18h 28mSpirit Airlines
Deal found 9/11$306
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/1012:17 pmIND - MDE
2 stops25h 59mMultiple Airlines
mié. 11/196:59 pmMDE - IND
1 stop27h 57mMultiple Airlines
Deal found 9/10$307
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/46:25 pmIND - BOG
1 stop19h 50mSpirit Airlines
lun. 10/132:10 pmBOG - IND
1 stop28h 33mSpirit Airlines
Deal found 9/10$313
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/255:30 amIND - BOG
1 stop7h 30mSpirit Airlines
sáb. 11/112:55 pmBOG - IND
1 stop9h 09mSpirit Airlines
Deal found 9/10$318
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/46:25 pmIND - BOG
1 stop19h 50mSpirit Airlines
mar. 10/142:10 pmBOG - IND
2 stops25h 57mSpirit Airlines
Deal found 9/10$322
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/1012:17 pmIND - MDE
2 stops49h 59mMultiple Airlines
lun. 11/176:59 pmMDE - IND
1 stop27h 57mMultiple Airlines
Deal found 9/9$330
This KAYAK deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/46:25 pmIND - BOG
1 stop19h 50mSpirit Airlines
dom. 10/122:10 pmBOG - IND
1 stop18h 38mSpirit Airlines
Deal found 9/10$332
This KAYAK deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/46:25 pmIND - BOG
1 stop19h 50mSpirit Airlines
vie. 10/102:10 pmBOG - IND
1 stop18h 38mSpirit Airlines
Deal found 9/10$335
This KAYAK deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/46:25 pmIND - BOG
1 stop19h 50mSpirit Airlines
sáb. 10/1112:55 pmBOG - IND
1 stop9h 09mSpirit Airlines
Deal found 9/10$337

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Indianapolis to South America that are best for you.

Fly from

Indianapolis

Fly to

South America

Route

Depart

Return

Price

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

lun. 11/10

6:35 am-2:16 pm

1 stop7h 41m

Medellín Jose Maria Cordova Intl

mié. 11/19

3:11 pm-10:56 pm

1 stop7h 45m

$280

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

lun. 11/10

12:17 pm-2:16 pm

2 stops25h 59m

Medellín Jose Maria Cordova Intl

mié. 11/19

6:59 pm-7:51 pm

1 stop24h 52m

$321

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

lun. 11/10

12:17 pm-2:16 pm

2 stops49h 59m

Medellín Jose Maria Cordova Intl

lun. 11/17

6:59 pm-10:56 pm

1 stop27h 57m

$330

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

jue. 11/13

6:35 am-6:04 pm

1 stop11h 29m

Medellín Jose Maria Cordova Intl

lun. 11/17

3:11 pm-10:56 pm

1 stop7h 45m

$330

IndianapolisCali

IND - CLO

INDCLO

Indianapolis

sáb. 10/25

10:15 am-1:23 pm

1 stop28h 08m

Cali Alfonso B. Aragon Intl

lun. 10/27

2:20 pm-7:43 pm

1 stop28h 23m

$353

IndianapolisCali

IND - CLO

INDCLO

Indianapolis

jue. 10/23

8:16 pm-1:23 pm

1 stop18h 07m

Cali Alfonso B. Aragon Intl

lun. 10/27

2:20 pm-9:20 am

2 stops18h 00m

$362

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

dom. 9/21

7:43 pm-12:23 pm

1 stop17h 40m

Cartagena Rafael Nunez

vie. 9/26

1:29 pm-10:53 am

1 stop20h 24m

$370

IndianapolisCali

IND - CLO

INDCLO

Indianapolis

jue. 10/23

8:16 pm-1:23 pm

1 stop18h 07m

Cali Alfonso B. Aragon Intl

lun. 10/27

5:05 am-7:43 pm

3 stops37h 38m

$386

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

mié. 10/1

5:45 am-1:00 pm

1 stop8h 15m

Medellín Jose Maria Cordova Intl

mié. 10/8

2:22 pm-9:48 am

1 stop18h 26m

$386

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

lun. 2/2

4:51 pm-2:16 pm

1 stop21h 25m

Medellín Jose Maria Cordova Intl

lun. 2/9

1:51 am-3:42 pm

1 stop13h 51m

$387

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 60 results
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Best time to book a flight from Indianapolis to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to South America

What is the cheapest month to book a flight from Indianapolis to South America?

Currently, May is the cheapest month in which you can book a flight from Indianapolis to South America (average of $359). Flying from Indianapolis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to SA?

Find hourly flight availability from Indianapolis to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

When flying from Indianapolis to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated septiembre 11, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and United Airlines from Indianapolis to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,960 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Spirit Airlines
6.3
Okay
8,023 reviews
Delta
8.0
Very good
7,960 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to South America?

    If you book a flight to South America from Indianapolis, you will be flying from Indianapolis, which is the city’s only airport. Indianapolis (IND) is located 8.3 mi from the center of Indianapolis.

  • How long is the flight from Indianapolis to South America?

    Spirit Airlines, Copa Airlines, and Delta can get you from Indianapolis to South America in just under 7h 41m. Your travel time can differ by up to 5h 14m. There are 2413 mi between Indianapolis and South America. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Indianapolis to South America?

    The most popular flight routes from Indianapolis to South America are Indianapolis - Quito Mariscal Sucr, Indianapolis - Medellín Jose Maria Cordova Intl and Indianapolis - Cartagena Rafael Nunez.

  • Can I find deals for flights from Indianapolis to South America that include hotel bookings?

    Yes. In addition to deals on Indianapolis to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to South America.

  • Can I find deals for business class flights from Indianapolis to South America?

    Yes. Cheapflights offers flight deals from Indianapolis to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to South America?

    Currently, May is the cheapest month in which you can book a flight from Indianapolis to South America (average of $359). Flying from Indianapolis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indianapolis to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Indianapolis to South America

Discover the top 5 airlines that operate flights from Indianapolis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$288Average$617FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$426Average$1,140FlexibilityNo cancel feeOn-time81%
DeltaCheapest$426Average$980FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$495Average$955FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$538Average$990FlexibilityNo cancel feeOn-time69%

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