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South America

$112+ Cheap flights from Indianapolis (IND) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
IND — BOG
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Indianapolis to South America

Cheapest flights from Indianapolis to South America
Explore the most affordable flight options available from Indianapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Priceline deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:15 am
IND
-
CTG
1 stop7h 04m
Spirit Airlines
Tue 3/241:24 pm
CTG
-
IND
1 stop8h 08m
Spirit Airlines
Deal found 1/27$260
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:45 am
IND
-
CTG
1 stop7h 25m
Spirit Airlines
Wed 3/181:24 pm
CTG
-
IND
1 stop8h 08m
Spirit Airlines
Deal found 1/27$263
This Priceline deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:15 am
IND
-
CTG
1 stop7h 04m
Spirit Airlines
Thu 4/161:21 pm
CTG
-
IND
1 stop8h 17m
Spirit Airlines
Deal found 1/27$277
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:15 am
IND
-
MDE
1 stop19h 06m
Spirit Airlines
Mon 3/231:17 am
MDE
-
IND
1 stop20h 15m
Spirit Airlines
Deal found 1/27$288
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/28:18 pm
IND
-
CTG
1 stop16h 52m
Spirit Airlines
Wed 3/111:21 pm
CTG
-
IND
1 stop8h 27m
Spirit Airlines
Deal found 1/27$288
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:45 am
IND
-
CTG
1 stop7h 25m
Spirit Airlines
Mon 3/91:21 pm
CTG
-
IND
1 stop8h 27m
Spirit Airlines
Deal found 1/27$290
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:15 am
IND
-
MDE
1 stop19h 06m
Spirit Airlines
Mon 3/302:17 pm
MDE
-
IND
1 stop31h 15m
Spirit Airlines
Deal found 1/28$295
This Priceline deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/168:18 pm
IND
-
CTG
1 stop16h 52m
Spirit Airlines
Wed 2/252:21 pm
CTG
-
IND
1 stop8h 27m
Spirit Airlines
Deal found 1/27$297
This Orbitz deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
IND
-
LIM
2 stops16h 35m
Spirit Airlines
Tue 3/311:30 pm
LIM
-
IND
2 stops14h 47m
Spirit Airlines
Deal found 1/27$304
This Cheapflightsfares deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/105:10 am
IND
-
BOG
1 stop8h 57m
Spirit Airlines
Mon 3/21:45 pm
BOG
-
IND
1 stop18h 47m
Spirit Airlines
Deal found 1/26$304
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/229:57 pm
IND
-
MDE
1 stop15h 58m
Multiple Airlines
Wed 3/111:50 pm
MDE
-
IND
1 stop17h 22m
Multiple Airlines
Deal found 1/26$306
This Orbitz deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:45 am
IND
-
LIM
1 stop16h 50m
Spirit Airlines
Wed 3/411:30 pm
LIM
-
IND
1 stop19h 53m
Spirit Airlines
Deal found 1/26$309

Find flight deals from Indianapolis to South America

Keep the following information in mind while searching for Indianapolis to South America flight deals. Data was last updated January 29, 2026.

Round-trip from

$260
(Priceline)

One-way from

$112
(Priceline)

Popular in

March

Cheapest in

February

Average price

$499
From Indianapolis to South America
Search Deals
One-way flight from Indianapolis to South America
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($82 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Indianapolis to South America that are best for you.

Fly from

Indianapolis

Fly to

South America

Route

Depart

Return

Price

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

Tue 3/10

5:45 am-12:10 pm

1 stop7h 25m

Cartagena Rafael Nunez

Wed 3/18

1:24 pm-10:32 pm

1 stop8h 08m

$263

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

Wed 4/8

6:15 am-12:19 pm

1 stop7h 04m

Cartagena Rafael Nunez

Thu 4/16

1:21 pm-10:38 pm

1 stop8h 17m

$277

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

Tue 3/3

5:45 am-1:10 pm

1 stop7h 25m

Cartagena Rafael Nunez

Mon 3/9

1:21 pm-10:48 pm

1 stop8h 27m

$290

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

Tue 3/24

6:15 am-12:21 am

1 stop19h 06m

Medellín Jose Maria Cordova Intl

Mon 3/30

2:17 pm-10:32 pm

1 stop31h 15m

$295

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

Mon 2/16

8:18 pm-1:10 pm

1 stop16h 52m

Cartagena Rafael Nunez

Wed 2/25

2:21 pm-10:48 pm

1 stop8h 27m

$297

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Tue 2/10

5:10 am-2:07 pm

1 stop8h 57m

Bogotá El Dorado

Mon 3/2

1:45 pm-8:32 am

1 stop18h 47m

$304

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

Tue 2/24

9:13 pm-1:55 pm

1 stop16h 42m

Medellín Jose Maria Cordova Intl

Wed 3/11

1:50 pm-8:12 am

1 stop17h 22m

$306

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

Wed 4/15

6:15 am-12:13 pm

1 stop6h 58m

Cartagena Rafael Nunez

Thu 4/23

1:21 pm-10:38 pm

1 stop8h 17m

$313

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

Fri 2/20

7:41 pm-2:13 pm

2 stops42h 32m

Medellín Jose Maria Cordova Intl

Tue 3/10

1:50 pm-9:21 am

1 stop18h 31m

$316

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

Fri 2/20

7:41 pm-2:13 pm

2 stops42h 32m

Medellín Jose Maria Cordova Intl

Wed 3/11

1:50 pm-8:12 am

1 stop17h 22m

$316

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 60 results
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Best time to book a flight from Indianapolis to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to South America

What is the cheapest month to book a flight from Indianapolis to South America?

Currently, March is the cheapest month in which you can book a flight from Indianapolis to South America (average of $87). Flying from Indianapolis to South America in April is currently the most expensive (average of $534). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 29, 2026.
See what other customers who have flown with Delta, LATAM Airlines, and United Airlines from Indianapolis to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,127 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,127 reviews
Delta
7.9
Good
8,127 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,918 reviews
Delta
7.9
Good
8,127 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,215 reviews
Delta
7.9
Good
8,127 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,206 reviews
Delta
7.9
Good
8,127 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,394 reviews
Delta
7.9
Good
8,127 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to South America?

    If you book a flight to South America from Indianapolis, you will be flying from Indianapolis, which is the city’s only airport. Indianapolis (IND) is located 8.3 mi from the center of Indianapolis.

  • How long is the flight from Indianapolis to South America?

    Spirit Airlines can get you from Indianapolis to South America in just under 7h 25m. Your travel time can differ by up to . There are 2127 mi between Indianapolis and South America.

  • What are the cheapest airlines to fly from Indianapolis to South America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $83. American Airlines flights start at $302 while deals on LATAM Airlines start at $312 one-way.

  • What are the most popular routes from Indianapolis to South America?

    The most popular flight routes from Indianapolis to South America are Indianapolis - Lima J Chavez Intl, Indianapolis - Medellín Jose Maria Cordova Intl and Indianapolis - Cartagena Rafael Nunez.

  • Can I find deals for flights from Indianapolis to South America that include hotel bookings?

    Yes. In addition to deals on Indianapolis to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to South America.

  • Can I find deals for business class flights from Indianapolis to South America?

    Yes. Cheapflights offers flight deals from Indianapolis to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to South America?

    Currently, March is the cheapest month in which you can book a flight from Indianapolis to South America (average of $87). Flying from Indianapolis to South America in April is currently the most expensive (average of $534). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Indianapolis to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Indianapolis to South America

Discover the top 6 airlines that operate flights from Indianapolis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$274Average$367FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$338Average$857FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$389Average$659FlexibilityNo cancel feeOn-time70%
DeltaCheapest$447Average$974FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$531Average$857FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$538Average$910FlexibilityNo cancel feeOn-time69%

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