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South America

$107+ Cheap flights from Columbus to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/29. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
jul. 6 — jul. 131
dom. 7/6
dom. 7/13
1 adult, Economy
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Cheap flight deals from Columbus to South America

Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated julio 1, 2025.

Round-trip from

$282
(Travelocity)

One-way from

$107
(eDestinos)

Popular in

July

Cheapest in

February

Average price

$1,620
From Columbus to South America
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One-way flight from Columbus to South America
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Highest demand for flights based on searches. 6% potential increase in price ($79 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($59 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Columbus to South America

Cheapest flights from Columbus to South America
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 1, 2025.

This Travelocity deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/225:05 amCMH - CTG
1 stop8h 10mSpirit Airlines
mar. 7/291:28 pmCTG - CMH
1 stop9h 50mSpirit Airlines
Deal found 6/29$282
This Expedia deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/185:15 amCMH - BOG
1 stop8h 44mSpirit Airlines
sáb. 8/301:54 pmBOG - CMH
1 stop8h 12mSpirit Airlines
Deal found 7/1$286
This FlightHub deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/205:15 amCMH - MDE
1 stop9h 07mSpirit Airlines
sáb. 8/2312:49 amMDE - CMH
1 stop9h 40mSpirit Airlines
Deal found 7/1$294
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/316:34 pmCMH - BOG
1 stop18h 26mMultiple Airlines
vie. 9/512:52 pmBOG - CMH
1 stop20h 29mMultiple Airlines
Deal found 6/30$385
This Mytrip deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/135:15 amCMH - CTG
1 stop8h 13mMultiple Airlines
mié. 8/203:43 pmCTG - CMH
3 stops18h 46mMultiple Airlines
Deal found 6/28$401
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/88:37 pmCMH - MDE
1 stop17h 35mMultiple Airlines
dom. 8/106:00 amMDE - CMH
3 stops17h 18mMultiple Airlines
Deal found 7/1$475
This FlightHub deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/305:15 amCMH - LIM
1 stop16h 30mSpirit Airlines
dom. 9/79:00 amLIM - CMH
1 stop25h 31mSpirit Airlines
Deal found 6/30$515
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/165:15 amCMH - LIM
3 stops23h 10mMultiple Airlines
vie. 8/222:50 amLIM - CMH
2 stops19h 16mMultiple Airlines
Deal found 7/1$549
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/138:34 amCMH - MDE
1 stop14h 31mAmerican Airlines
mié. 11/191:25 amMDE - CMH
1 stop15h 01mAmerican Airlines
Deal found 7/1$555
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/136:30 amCMH - MDE
1 stop15h 35mUnited Airlines
vie. 11/2110:45 amMDE - CMH
1 stop11h 27mUnited Airlines
Deal found 6/30$565
This Trip.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/156:00 amCMH - GRU
2 stops43h 10mMultiple Airlines
vie. 8/224:10 amGRU - CMH
2 stops18h 36mMultiple Airlines
Deal found 6/30$573
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/66:30 amCMH - CTG
2 stops26h 23mUnited Airlines
mar. 11/119:48 amCTG - CMH
2 stops36h 24mUnited Airlines
Deal found 6/30$578

Cheapflights Fare Finder

Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 1, 2025.
Use the filters below to find and compare flights from Columbus to South America that are best for you.

Fly from

Columbus

Fly to

South America

Route

Depart

Return

Price

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

mar. 7/22

5:05 am-12:15 pm

1 stop8h 10m

Cartagena Rafael Nunez

mar. 7/29

1:28 pm-12:18 am

1 stop9h 50m

$282

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

lun. 8/18

5:15 am-12:59 pm

1 stop8h 44m

Bogotá El Dorado

sáb. 8/30

1:54 pm-11:06 pm

1 stop8h 12m

$286

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

mié. 8/20

5:15 am-1:22 pm

1 stop9h 07m

Medellín Jose Maria Cordova Intl

sáb. 8/23

12:49 am-11:29 am

1 stop9h 40m

$294

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

dom. 8/31

6:34 pm-12:00 pm

1 stop18h 26m

Bogotá El Dorado

vie. 9/5

12:52 pm-10:21 am

1 stop20h 29m

$385

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

mié. 8/13

5:15 am-12:28 pm

1 stop8h 13m

Cartagena Rafael Nunez

mié. 8/20

3:43 pm-11:29 am

3 stops18h 46m

$401

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

vie. 8/8

8:37 pm-1:12 pm

1 stop17h 35m

Medellín Jose Maria Cordova Intl

dom. 8/10

6:00 am-12:18 am

3 stops17h 18m

$475

ColumbusLima

CMH - LIM

CMHLIM

Columbus

sáb. 8/30

5:15 am-8:45 pm

1 stop16h 30m

Lima J Chavez Intl

dom. 9/7

9:00 am-11:31 am

1 stop25h 31m

$515

ColumbusSao Paulo

CMH - GRU

CMHGRU

Columbus

vie. 8/15

6:00 am-2:10 am

2 stops43h 10m

Sao Paulo Guarulhos Intl

jue. 8/21

4:10 am-11:47 pm

2 stops20h 37m

$544

ColumbusLima

CMH - LIM

CMHLIM

Columbus

sáb. 8/16

5:15 am-3:25 am

3 stops23h 10m

Lima J Chavez Intl

vie. 8/22

2:50 am-11:06 pm

2 stops19h 16m

$549

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

mié. 8/13

11:42 am-4:54 am

1 stop18h 12m

Bogotá El Dorado

mar. 8/19

12:14 am-3:59 pm

1 stop14h 45m

$553

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/29

Showing 1-10 of 57 results
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Best time to book a flight from Columbus to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to South America

What is the cheapest month to book a flight from Columbus to South America?

Currently, May is the cheapest month in which you can book a flight from Columbus to South America (average of $359). Flying from Columbus to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SA?

Find hourly flight availability from Columbus to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Columbus to South America as you normally would.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated julio 1, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and Copa Airlines from Columbus to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,801 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,465 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,858 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Columbus to South America one-way?

    One-way options have recently been found by users for as low as $107 on Spirit Airlines. Other airlines that offer cheap prices include Copa Airlines from $287 and United Airlines from $402 one-way.

  • What are the most popular routes from Columbus to South America?

    Most travelers choose Columbus - Lima J Chavez Intl, Columbus - Medellín Jose Maria Cordova Intl or Columbus - Cartagena Rafael Nunez when deciding on the best route from Columbus to South America.

  • Can I find deals for flights from Columbus to South America that include hotel bookings?

    Yes. In addition to deals on Columbus to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to South America.

  • Can I find deals for business class flights from Columbus to South America?

    Yes. Cheapflights offers flight deals from Columbus to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to South America?

    Currently, May is the cheapest month in which you can book a flight from Columbus to South America (average of $359). Flying from Columbus to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Columbus to South America

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Top 6 airlines flying from Columbus to South America

Discover the top 6 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$261Average$418FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$370Average$898FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$401Average$901FlexibilityNo cancel feeOn-time69%
DeltaCheapest$414Average$931FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$423Average$858FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

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