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South America

$111+ Cheap flights from Columbus to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Columbus to South America

Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated August 14, 2025.

Round-trip from

$256
(FlightHub)

One-way from

$111
(FlightHub)
From Columbus to South America
Search Deals
One-way flight from Columbus to South America
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Find flight deals from Columbus to South America

Cheapest flights from Columbus to South America
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This FlightHub deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:45 amCMH - CTG
1 stop6h 23mSpirit Airlines
Wed 12/102:16 pmCTG - CMH
1 stop6h 56mSpirit Airlines
Deal found 8/14$256
This FlightHub deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/245:15 amCMH - MDE
1 stop20h 13mSpirit Airlines
Mon 9/291:24 amMDE - CMH
1 stop9h 17mSpirit Airlines
Deal found 8/13$264
This FlightHub deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:15 amCMH - MDE
1 stop8h 59mSpirit Airlines
Fri 9/261:24 amMDE - CMH
1 stop9h 17mSpirit Airlines
Deal found 8/13$267
This FlightHub deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:45 amCMH - CTG
1 stop6h 23mSpirit Airlines
Tue 11/112:16 pmCTG - CMH
1 stop6h 56mSpirit Airlines
Deal found 8/12$267
This FlightHub deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/245:15 amCMH - MDE
1 stop20h 13mSpirit Airlines
Thu 9/251:24 amMDE - CMH
1 stop9h 17mSpirit Airlines
Deal found 8/11$274
This FlightHub deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:15 amCMH - MDE
1 stop20h 13mSpirit Airlines
Mon 9/291:24 amMDE - CMH
1 stop9h 17mSpirit Airlines
Deal found 8/13$275
This Cheapflightsfares deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:15 amCMH - MDE
1 stop8h 59mSpirit Airlines
Sun 9/281:24 amMDE - CMH
1 stop9h 17mSpirit Airlines
Deal found 8/13$277
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:15 amCMH - MDE
1 stop8h 59mSpirit Airlines
Tue 9/301:24 amMDE - CMH
1 stop9h 17mSpirit Airlines
Deal found 8/13$278
This CheapOair deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:15 amCMH - CTG
1 stop8h 08mSpirit Airlines
Mon 10/61:29 pmCTG - CMH
1 stop21h 12mSpirit Airlines
Deal found 8/11$282
This Expedia deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/288:20 pmCMH - MDE
1 stop17h 54mSpirit Airlines
Sat 10/41:24 amMDE - CMH
1 stop9h 26mSpirit Airlines
Deal found 8/14$284
This FlightHub deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:15 amCMH - MDE
1 stop20h 13mSpirit Airlines
Fri 9/261:24 amMDE - CMH
1 stop9h 17mSpirit Airlines
Deal found 8/13$285
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/225:15 amCMH - MDE
1 stop8h 59mSpirit Airlines
Tue 9/301:24 amMDE - CMH
1 stop9h 17mSpirit Airlines
Deal found 8/13$290

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Columbus to South America that are best for you.

Fly from

Columbus

Fly to

South America

Route

Depart

Return

Price

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 9/24

5:15 am-12:28 am

1 stop20h 13m

Medellín Jose Maria Cordova Intl

Mon 9/29

1:24 am-11:41 am

1 stop9h 17m

$264

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 9/24

5:15 am-12:28 am

1 stop20h 13m

Medellín Jose Maria Cordova Intl

Fri 9/26

1:24 am-11:41 am

1 stop9h 17m

$264

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 9/23

5:15 am-1:14 pm

1 stop8h 59m

Medellín Jose Maria Cordova Intl

Fri 9/26

1:24 am-11:41 am

1 stop9h 17m

$267

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Thu 11/6

6:45 am-1:08 pm

1 stop6h 23m

Cartagena Rafael Nunez

Tue 11/11

2:16 pm-9:12 pm

1 stop6h 56m

$267

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 10/1

5:15 am-12:28 am

1 stop20h 13m

Medellín Jose Maria Cordova Intl

Sun 10/5

1:24 am-6:58 pm

1 stop16h 34m

$274

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 9/24

5:15 am-12:28 am

1 stop20h 13m

Medellín Jose Maria Cordova Intl

Thu 9/25

1:24 am-11:41 am

1 stop9h 17m

$274

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Fri 9/26

5:15 am-12:28 am

1 stop20h 13m

Medellín Jose Maria Cordova Intl

Mon 9/29

1:24 am-11:41 am

1 stop9h 17m

$275

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 9/23

5:15 am-1:14 pm

1 stop8h 59m

Medellín Jose Maria Cordova Intl

Sun 9/28

1:24 am-11:41 am

1 stop9h 17m

$277

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 9/23

5:15 am-1:14 pm

1 stop8h 59m

Medellín Jose Maria Cordova Intl

Tue 9/30

1:24 am-11:41 am

1 stop9h 17m

$278

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 9/23

5:15 am-1:14 pm

1 stop8h 59m

Medellín Jose Maria Cordova Intl

Mon 9/29

1:24 am-11:41 am

1 stop9h 17m

$278

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 53 results
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Best time to book a flight from Columbus to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to South America

What is the cheapest month to book a flight from Columbus to South America?

Currently, May is the cheapest month in which you can book a flight from Columbus to South America (average of $359). Flying from Columbus to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SA?

Find hourly flight availability from Columbus to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Columbus to South America as you normally would.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated August 14, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and United Airlines from Columbus to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,840 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,916 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Spirit Airlines
6.3
Okay
8,045 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the most popular routes from Columbus to South America?

    Most travelers choose Columbus - Lima J Chavez Intl, Columbus - Medellín Jose Maria Cordova Intl or Columbus - Cartagena Rafael Nunez when deciding on the best route from Columbus to South America.

  • Can I find deals for flights from Columbus to South America that include hotel bookings?

    Yes. In addition to deals on Columbus to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to South America.

  • Can I find deals for business class flights from Columbus to South America?

    Yes. Cheapflights offers flight deals from Columbus to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to South America?

    Currently, May is the cheapest month in which you can book a flight from Columbus to South America (average of $359). Flying from Columbus to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Columbus to South America

Discover the top 6 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$259Average$429FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$370Average$888FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$401Average$875FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$423Average$848FlexibilityNo cancel feeOn-time71%
DeltaCheapest$539Average$938FlexibilityNo cancel feeOn-timeN/A
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

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