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South America

$245+ Cheap flights from Columbus to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/13. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Mar 22 — Mar 291
Sun 3/22
Sun 3/29
1 adult, Economy
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Cheap flight deals from Columbus to South America

Cheapest flights from Columbus to South America
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2026.

This CheapOair deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:25 am
CMH
-
MDE
1 stop7h 43m
Spirit Airlines
Mon 4/201:11 am
MDE
-
CMH
1 stop19h 41m
Spirit Airlines
Deal found 2/18$355
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/78:03 pm
CMH
-
MDE
2 stops42h 19m
Multiple Airlines
Mon 4/131:17 am
MDE
-
CMH
1 stop20h 32m
Multiple Airlines
Deal found 2/17$363
This CheapOair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1612:35 pm
CMH
-
CTG
1 stop24h 30m
Spirit Airlines
Mon 4/201:11 pm
CTG
-
CMH
1 stop7h 41m
Spirit Airlines
Deal found 2/20$363
This CheapOair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:00 am
CMH
-
BOG
1 stop8h 08m
Spirit Airlines
Wed 5/132:07 pm
BOG
-
CMH
1 stop20h 26m
Spirit Airlines
Deal found 2/20$365
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:00 pm
CMH
-
BOG
2 stops19h 08m
Multiple Airlines
Mon 4/272:07 pm
BOG
-
CMH
1 stop30h 45m
Multiple Airlines
Deal found 2/18$368
This Cheapflightsfares deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:45 am
CMH
-
MDE
1 stop8h 37m
Spirit Airlines
Fri 4/101:17 am
MDE
-
CMH
1 stop7h 24m
Spirit Airlines
Deal found 2/17$381
This CheapOair deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/710:40 am
CMH
-
MDE
2 stops24h 11m
Spirit Airlines
Tue 4/142:17 pm
MDE
-
CMH
1 stop7h 32m
Spirit Airlines
Deal found 2/18$383
This Cheapflightsfares deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:05 am
CMH
-
BOG
1 stop6h 50m
Spirit Airlines
Thu 4/92:10 pm
BOG
-
CMH
1 stop18h 31m
Spirit Airlines
Deal found 2/18$383
This CheapOair deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:00 am
CMH
-
BOG
1 stop8h 08m
Spirit Airlines
Tue 4/282:07 pm
BOG
-
CMH
2 stops21h 05m
Spirit Airlines
Deal found 2/18$385
This Expedia deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:45 am
CMH
-
BOG
1 stop8h 26m
Spirit Airlines
Mon 4/272:07 pm
BOG
-
CMH
2 stops21h 05m
Spirit Airlines
Deal found 2/20$390
This CheapOair deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:00 am
CMH
-
BOG
1 stop8h 08m
Spirit Airlines
Wed 4/292:07 pm
BOG
-
CMH
2 stops21h 05m
Spirit Airlines
Deal found 2/18$394
This Travelocity deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:15 am
CMH
-
CTG
1 stop6h 55m
Spirit Airlines
Fri 3/62:21 pm
CTG
-
CMH
1 stop9h 11m
Spirit Airlines
Deal found 2/18$395

Find flight deals from Columbus to South America

Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated February 20, 2026.

Round-trip from

$355
(CheapOair)

One-way from

$151
(Super.com)

Popular in

February

Cheapest in

October

Average price

$1,104
From Columbus to South America
Search Deals
One-way flight from Columbus to South America
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($62 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($49 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
Use the filters below to find and compare flights from Columbus to South America that are best for you.

Fly from

Columbus

Fly to

South America

Route

Depart

Return

Price

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 4/15

6:25 am-1:08 pm

1 stop7h 43m

Medellín Jose Maria Cordova Intl

Mon 4/20

1:11 am-9:52 pm

1 stop19h 41m

$355

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 4/7

10:40 am-1:22 pm

1 stop27h 42m

Medellín Jose Maria Cordova Intl

Tue 4/14

2:17 pm-10:49 pm

1 stop7h 32m

$355

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 4/7

8:03 pm-1:22 pm

2 stops42h 19m

Medellín Jose Maria Cordova Intl

Mon 4/13

1:17 am-10:49 pm

1 stop20h 32m

$363

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Fri 4/17

12:35 pm-12:16 am

1 stop12h 41m

Medellín Jose Maria Cordova Intl

Sun 4/19

2:06 pm-11:33 am

1 stop20h 27m

$367

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Thu 4/23

7:00 pm-1:08 pm

2 stops19h 08m

Bogotá El Dorado

Mon 4/27

2:07 pm-9:52 pm

1 stop30h 45m

$368

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Thu 5/7

6:00 am-1:08 pm

1 stop8h 08m

Medellín Jose Maria Cordova Intl

Thu 5/14

2:06 pm-11:33 am

1 stop20h 27m

$381

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 4/1

5:45 am-1:22 pm

1 stop8h 37m

Medellín Jose Maria Cordova Intl

Fri 4/10

1:17 am-9:41 am

1 stop7h 24m

$381

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Wed 4/22

6:00 am-1:08 pm

1 stop8h 08m

Bogotá El Dorado

Wed 4/29

2:07 pm-12:12 pm

2 stops21h 05m

$394

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Tue 3/3

6:15 am-1:10 pm

1 stop6h 55m

Cartagena Rafael Nunez

Fri 3/6

2:21 pm-11:32 pm

1 stop9h 11m

$395

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Tue 4/21

6:00 am-1:08 pm

1 stop8h 08m

Bogotá El Dorado

Mon 4/27

2:07 pm-9:52 pm

1 stop30h 45m

$405

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 60 results
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Best time to book a flight from Columbus to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to South America

What is the cheapest month to book a flight from Columbus to South America?

Currently, February is the cheapest month in which you can book a flight from Columbus to South America (average of $244). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 20, 2026.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Columbus to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,222 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,222 reviews
Delta
7.9
Good
8,222 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,919 reviews
Delta
7.9
Good
8,222 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,323 reviews
Delta
7.9
Good
8,222 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Air Canada
7.1
Good
10,732 reviews
Delta
7.9
Good
8,222 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,478 reviews
Delta
7.9
Good
8,222 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus to South America?

    For as low as $355, Spirit Airlines can have you in South America from Columbus in 7h 43m. There are 2382 mi between Columbus and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Columbus to South America?

    Most travelers choose Columbus - Rio de Janeiro–Galeão Intl, Columbus - Rio de Janeiro Santos Dumont or Columbus - Lima J Chavez Intl when deciding on the best route from Columbus to South America.

  • Can I find deals for flights from Columbus to South America that include hotel bookings?

    Yes. In addition to deals on Columbus to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to South America.

  • Can I find deals for business class flights from Columbus to South America?

    Yes. Cheapflights offers flight deals from Columbus to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to South America?

    Currently, February is the cheapest month in which you can book a flight from Columbus to South America (average of $244). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Columbus to South America

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Top 5 airlines flying from Columbus to South America

Discover the top 5 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$244Average$388FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$443Average$772FlexibilityNo cancel feeOn-time71%
DeltaCheapest$552Average$874FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$562Average$806FlexibilityNo cancel feeOn-time81%
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

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