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South America

$146+ Cheap flights from Columbus to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
jan 1 — jan 81
qui 1/1
qui 1/8
1 adult, Economy
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Cheap flight deals from Columbus to South America

Cheapest flights from Columbus to South America
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on dezembro 2, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/3111:14 amCMH - MDE
1 stop14h 14mMultiple Airlines
ter 1/138:21 pmMDE - CMH
2 stops27h 06mMultiple Airlines
Deal found 11/30$460
This Mytrip deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 12/86:00 amCMH - MDE
2 stops28h 55mSpirit Airlines
qua 12/102:05 amMDE - CMH
2 stops17h 33mSpirit Airlines
Deal found 11/30$468
This KAYAK deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 12/68:33 pmCMH - MDE
2 stops17h 24mSpirit Airlines
ter 12/92:05 amMDE - CMH
2 stops17h 33mSpirit Airlines
Deal found 11/30$471
This Kiwi.com deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/148:33 pmCMH - CTG
1 stop16h 37mMultiple Airlines
dom 12/212:15 pmCTG - CMH
2 stops28h 35mMultiple Airlines
Deal found 12/1$483
This KAYAK deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 12/128:33 pmCMH - CTG
1 stop16h 37mSpirit Airlines
ter 12/162:15 pmCTG - CMH
2 stops29h 23mSpirit Airlines
Deal found 12/1$497
This KAYAK deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 12/118:33 pmCMH - MDE
1 stop28h 36mSpirit Airlines
sáb 12/132:05 amMDE - CMH
1 stop20h 09mSpirit Airlines
Deal found 11/29$499
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 12/86:00 amCMH - MDE
1 stop29h 50mMultiple Airlines
qui 12/1111:50 amMDE - CMH
1 stop7h 48mMultiple Airlines
Deal found 11/30$510
This Kiwi.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/309:13 pmCMH - MDE
1 stop13h 42mMultiple Airlines
ter 1/138:21 pmMDE - CMH
2 stops27h 06mMultiple Airlines
Deal found 11/30$514
This KAYAK deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 12/226:28 pmCMH - CTG
2 stops18h 42mSpirit Airlines
sáb 12/272:15 pmCTG - CMH
1 stop27h 18mSpirit Airlines
Deal found 12/2$522
This KAYAK deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 12/186:28 pmCMH - CTG
2 stops18h 42mSpirit Airlines
seg 12/222:15 pmCTG - CMH
2 stops33h 42mSpirit Airlines
Deal found 11/29$525
This Mytrip deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/26:00 amCMH - CTG
1 stop7h 25mSpirit Airlines
ter 12/92:15 pmCTG - CMH
2 stops20h 04mSpirit Airlines
Deal found 12/1$534
This KAYAK deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 12/226:28 pmCMH - CTG
2 stops18h 42mSpirit Airlines
seg 12/292:15 pmCTG - CMH
1 stop27h 18mSpirit Airlines
Deal found 12/1$536

Find flight deals from Columbus to South America

Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated dezembro 2, 2025.

Round-trip from

$286
(Cheapflightsfares)

One-way from

$146
(Kiwi.com)
From Columbus to South America
Search Deals
One-way flight from Columbus to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated dezembro 2, 2025.
Use the filters below to find and compare flights from Columbus to South America that are best for you.

Fly from

Columbus

Fly to

South America

Route

Depart

Return

Price

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

seg 1/26

5:45 am-2:15 pm

1 stop8h 30m

Medellín Jose Maria Cordova Intl

qua 1/28

3:15 pm-11:27 pm

1 stop8h 12m

$305

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

seg 1/26

5:45 am-1:15 pm

1 stop7h 30m

Cartagena Rafael Nunez

qui 1/29

2:21 pm-11:27 pm

1 stop9h 06m

$310

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

seg 2/2

5:45 am-2:07 pm

1 stop8h 22m

Bogotá El Dorado

qui 2/5

1:45 pm-11:19 pm

1 stop9h 34m

$315

ColumbusGuayaquil

CMH - GYE

CMHGYE

Columbus

seg 1/26

5:45 am-12:21 am

1 stop18h 36m

Guayaquil Jose Joaquin de Olmedo

ter 1/27

1:26 am-11:19 pm

2 stops21h 53m

$328

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

sáb 2/7

5:45 am-2:07 pm

1 stop8h 22m

Bogotá El Dorado

qui 2/12

1:45 pm-11:53 pm

1 stop10h 08m

$345

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

qui 2/5

10:40 am-1:15 pm

1 stop26h 35m

Cartagena Rafael Nunez

seg 2/9

2:21 pm-11:27 pm

1 stop9h 06m

$348

ColumbusLima

CMH - LIM

CMHLIM

Columbus

ter 2/3

5:45 am-10:35 pm

1 stop16h 50m

Lima J Chavez Intl

ter 3/3

11:30 pm-9:40 am

1 stop10h 10m

$358

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

sáb 1/31

5:45 am-2:07 pm

1 stop8h 22m

Bogotá El Dorado

dom 2/8

1:45 pm-11:19 pm

1 stop9h 34m

$363

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

seg 1/26

5:45 am-2:07 pm

1 stop8h 22m

Bogotá El Dorado

qua 1/28

1:45 pm-11:19 pm

1 stop9h 34m

$372

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

dom 1/18

12:55 pm-2:15 pm

2 stops25h 20m

Medellín Jose Maria Cordova Intl

sáb 1/31

3:15 pm-9:40 am

1 stop18h 25m

$389

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/30

Showing 1-10 of 60 results
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Best time to book a flight from Columbus to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to South America

What is the cheapest month to book a flight from Columbus to South America?

Currently, February is the cheapest month in which you can book a flight from Columbus to South America (average of $257). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SA?

Find hourly flight availability from Columbus to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated dezembro 2, 2025.

It’s typically best to fly out from Columbus to South America in the evening. Doing so could potentially save you 12% on the flight price compared to flying in the afternoon, which is usually more expensive.

What is the cheapest day to fly from Columbus to South America?

Use this chart to determine the cheapest time to fly round-trip from Columbus to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Columbus to South America flight should consider departing on Tuesday mornings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated dezembro 2, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and United Airlines from Columbus to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,890 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,063 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,045 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,156 reviews
Delta
7.9
Good
8,011 reviews

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus to South America?

    For as low as $305, Spirit Airlines can have you in South America from Columbus in 8h 30m. There are 2382 mi between Columbus and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Columbus to South America?

    Most travelers choose Columbus - Medellín Jose Maria Cordova Intl, Columbus - Cartagena Rafael Nunez or Columbus - Lima J Chavez Intl when deciding on the best route from Columbus to South America.

  • Can I find deals for flights from Columbus to South America that include hotel bookings?

    Yes. In addition to deals on Columbus to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to South America.

  • Can I find deals for business class flights from Columbus to South America?

    Yes. Cheapflights offers flight deals from Columbus to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to South America?

    Currently, February is the cheapest month in which you can book a flight from Columbus to South America (average of $257). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Columbus to South America

Discover the top 6 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated dezembro 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$261Average$392FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$443Average$787FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$534Average$613FlexibilityNo cancel feeOn-time69%
DeltaCheapest$552Average$888FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$555Average$825FlexibilityNo cancel feeOn-time81%
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

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