$86+ Cheap flights from Columbus to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Mar 4 — Mar 111
1 adult, Economy
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Find cheap flights from Columbus to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Columbus to South AmericaExplore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.
This Expedia deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:45 am
CMH
- MDE
1 stop8h 10m
Spirit Airlines
Tue 3/102:15 pm
MDE
- CMH
1 stop8h 17m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$203
This Orbitz deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:15 am
CMH
- LIM
1 stop16h 20m
Spirit Airlines
Mon 3/910:30 pm
LIM
- CMH
2 stops24h 23m
Spirit Airlines
Deal found 1/31![Spirit Airlines logo]()
$223
This Expedia deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/211:39 am
CMH
- GYE
1 stop12h 25m
Spirit Airlines
Mon 3/911:59 pm
GYE
- CMH
1 stop9h 45m
Spirit Airlines
Deal found 1/31![Spirit Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:40 am
CMH
- MDE
1 stop14h 41m
Spirit Airlines
Mon 3/231:17 am
MDE
- CMH
1 stop20h 32m
Spirit Airlines
Deal found 1/31![Spirit Airlines logo]()
$269
This Priceline deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:40 am
CMH
- MDE
1 stop14h 41m
Spirit Airlines
Thu 4/92:17 pm
MDE
- CMH
1 stop7h 32m
Spirit Airlines
Deal found 2/2![Spirit Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:37 pm
CMH
- BOG
1 stop17h 10m
Multiple Airlines
Fri 4/1012:50 pm
BOG
- CMH
1 stop19h 22m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$289
This CheapOair deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:25 am
CMH
- MDE
1 stop7h 48m
Spirit Airlines
Mon 4/201:37 am
MDE
- CMH
1 stop19h 36m
Spirit Airlines
Deal found 2/2![Spirit Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:37 pm
CMH
- BOG
1 stop17h 10m
Multiple Airlines
Thu 4/912:50 pm
BOG
- CMH
1 stop9h 29m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$305
This Expedia deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:05 am
CMH
- BOG
1 stop6h 50m
Spirit Airlines
Tue 3/1712:50 pm
BOG
- CMH
1 stop9h 29m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$308
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:45 am
CMH
- BOG
1 stop7h 02m
Spirit Airlines
Thu 4/912:50 pm
BOG
- CMH
1 stop9h 29m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2010:54 am
CMH
- GYE
2 stops37h 10m
Multiple Airlines
Mon 3/911:59 pm
GYE
- CMH
1 stop9h 45m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$312
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:40 am
CMH
- MDE
1 stop14h 41m
Spirit Airlines
Fri 4/101:17 am
MDE
- CMH
1 stop7h 24m
Spirit Airlines
Deal found 2/2![Spirit Airlines logo]()
$313
Best flights from Columbus to South AmericaDiscover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 2, 2026.
Discover carefully curated flight deals from Columbus to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 2, 2026.
This Expedia deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:45 am
CMH
- MDE
1 stop8h 10m
Spirit Airlines
Tue 3/102:15 pm
MDE
- CMH
1 stop8h 17m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:37 pm
CMH
- BOG
1 stop17h 10m
Multiple Airlines
Wed 4/812:50 pm
BOG
- CMH
1 stop9h 29m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$305
This Orbitz deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:15 am
CMH
- LIM
1 stop16h 20m
Spirit Airlines
Mon 3/910:30 pm
LIM
- CMH
2 stops24h 23m
Spirit Airlines
Deal found 1/31![Spirit Airlines logo]()
$223
This Avianca deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:37 pm
CMH
- CTG
3 stops17h 58m
Avianca
Mon 4/205:30 pm
CTG
- CMH
2 stops15h 15m
Avianca
Deal found 2/1![Avianca logo]()
$541
This Expedia deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/211:39 am
CMH
- GYE
1 stop12h 25m
Spirit Airlines
Mon 3/911:59 pm
GYE
- CMH
1 stop9h 45m
Spirit Airlines
Deal found 1/31![Spirit Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:37 pm
CMH
- BOG
1 stop17h 10m
Multiple Airlines
Thu 4/912:50 pm
BOG
- CMH
1 stop9h 29m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:40 am
CMH
- MDE
1 stop14h 41m
Spirit Airlines
Mon 3/231:17 am
MDE
- CMH
1 stop20h 32m
Spirit Airlines
Deal found 1/31![Spirit Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:10 am
CMH
- UIO
1 stop18h 15m
United Airlines
Fri 5/812:35 am
UIO
- CMH
1 stop9h 17m
United Airlines
Deal found 2/2![United Airlines logo]()
$675
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2010:54 am
CMH
- GYE
2 stops37h 10m
Multiple Airlines
Mon 3/911:59 pm
GYE
- CMH
1 stop9h 45m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$312
This Priceline deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:40 am
CMH
- MDE
1 stop14h 41m
Spirit Airlines
Thu 4/92:17 pm
MDE
- CMH
1 stop7h 32m
Spirit Airlines
Deal found 2/2![Spirit Airlines logo]()
$275
This Mytrip deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:15 am
CMH
- MDE
2 stops13h 30m
Multiple Airlines
Tue 3/109:13 am
MDE
- CMH
3 stops13h 19m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$330
This FlightHub deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:07 am
CMH
- SCL
1 stop23h 43m
LATAM Airlines
Wed 5/2010:55 pm
SCL
- CMH
1 stop18h 45m
LATAM Airlines
Deal found 2/1![LATAM Airlines logo]()
$802
This Air Canada deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/229:30 am
CMH
- GRU
1 stop24h 05m
Air Canada
Sun 3/299:45 pm
GRU
- CMH
1 stop24h 07m
Air Canada
Deal found 1/30![Air Canada logo]()
$840
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1110:40 am
CMH
- GYE
1 stop13h 24m
Multiple Airlines
Sat 4/1811:59 pm
GYE
- CMH
2 stops13h 42m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$331
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:45 am
CMH
- BOG
1 stop7h 02m
Spirit Airlines
Thu 4/912:50 pm
BOG
- CMH
1 stop9h 29m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$311
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:40 am
CMH
- MDE
1 stop14h 41m
Spirit Airlines
Fri 4/101:17 am
MDE
- CMH
1 stop7h 24m
Spirit Airlines
Deal found 2/2![Spirit Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:45 am
CMH
- BOG
1 stop7h 02m
Multiple Airlines
Fri 4/1012:50 pm
BOG
- CMH
1 stop19h 22m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$356
This FlightHub deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:36 am
CMH
- CTG
2 stops14h 04m
Avianca
Mon 5/111:30 pm
CTG
- CMH
3 stops19h 10m
Avianca
Deal found 1/31![Avianca logo]()
$554
This CheapOair deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:25 am
CMH
- MDE
1 stop7h 48m
Spirit Airlines
Tue 4/212:10 pm
MDE
- CMH
2 stops21h 56m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:15 am
CMH
- MDE
1 stop7h 58m
Multiple Airlines
Tue 2/2410:28 pm
MDE
- CMH
2 stops43h 36m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$362
This Cheapflightsfares deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:45 am
CMH
- BOG
1 stop7h 02m
Spirit Airlines
Fri 4/1012:50 pm
BOG
- CMH
1 stop9h 29m
Spirit Airlines
Deal found 2/2![Spirit Airlines logo]()
$321
This Mytrip deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:45 am
CMH
- MDE
2 stops29h 06m
Multiple Airlines
Tue 3/2410:28 pm
MDE
- CMH
3 stops23h 21m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1911:42 am
CMH
- UIO
1 stop12h 48m
United Airlines
Wed 3/2512:35 am
UIO
- CMH
1 stop9h 26m
United Airlines
Deal found 2/2![United Airlines logo]()
$693
This Orbitz deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/2211:39 am
CMH
- GYE
1 stop12h 25m
Spirit Airlines
Mon 2/2312:59 am
GYE
- CMH
1 stop9h 45m
Spirit Airlines
Deal found 1/30![Spirit Airlines logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/75:45 am
CMH
- BOG
1 stop7h 02m
Multiple Airlines
Sat 3/1412:50 pm
BOG
- CMH
2 stops24h 06m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/184:57 pm
CMH
- UIO
1 stop13h 03m
United Airlines
Tue 4/2112:35 am
UIO
- CMH
1 stop9h 22m
United Airlines
Deal found 2/1![United Airlines logo]()
$699
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:15 am
CMH
- BOG
1 stop7h 55m
Spirit Airlines
Wed 4/812:50 pm
BOG
- CMH
1 stop9h 29m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$335
This KAYAK deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/112:50 pm
CMH
- SCL
1 stop18h 25m
LATAM Airlines
Mon 6/2211:05 pm
SCL
- CMH
2 stops33h 53m
LATAM Airlines
Deal found 1/31![LATAM Airlines logo]()
$825
This FlightHub deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/219:30 am
CMH
- GRU
1 stop24h 05m
Air Canada
Tue 3/319:45 pm
GRU
- CMH
1 stop24h 07m
Air Canada
Deal found 1/30![Air Canada logo]()
$840
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:45 am
CMH
- LIM
1 stop16h 50m
Multiple Airlines
Sat 4/1810:30 pm
LIM
- CMH
2 stops39h 11m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$392
Last-minute flights from Columbus to South AmericaDiscover last-minute flight deals from Columbus to South America. Data last updated February 2, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to South America. Data last updated February 2, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:45 am
CMH
- MDE
1 stop8h 10m
Spirit Airlines
Sat 2/282:50 pm
MDE
- CMH
1 stop9h 03m
Spirit Airlines
Deal found 2/2![Spirit Airlines logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2010:54 am
CMH
- GYE
2 stops37h 10m
Multiple Airlines
Mon 3/911:59 pm
GYE
- CMH
1 stop9h 45m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$312
This Orbitz deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:15 am
CMH
- LIM
1 stop16h 20m
Spirit Airlines
Mon 3/910:30 pm
LIM
- CMH
2 stops24h 23m
Spirit Airlines
Deal found 1/31![Spirit Airlines logo]()
$223
This Expedia deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:45 am
CMH
- MDE
1 stop8h 10m
Spirit Airlines
Tue 3/102:15 pm
MDE
- CMH
1 stop8h 17m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:37 pm
CMH
- BOG
1 stop17h 10m
Multiple Airlines
Fri 4/1012:50 pm
BOG
- CMH
1 stop19h 22m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:37 pm
CMH
- BOG
1 stop17h 10m
Multiple Airlines
Thu 4/912:50 pm
BOG
- CMH
1 stop9h 29m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:45 am
CMH
- BOG
1 stop7h 02m
Multiple Airlines
Wed 4/82:10 pm
BOG
- CMH
2 stops28h 08m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$327
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:45 am
CMH
- BOG
1 stop7h 02m
Spirit Airlines
Thu 4/912:50 pm
BOG
- CMH
1 stop9h 29m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:15 am
CMH
- BOG
1 stop7h 55m
Multiple Airlines
Fri 4/1012:50 pm
BOG
- CMH
1 stop19h 22m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$329
This Cheapflightsfares deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:45 am
CMH
- BOG
1 stop7h 02m
Spirit Airlines
Fri 4/102:10 pm
BOG
- CMH
1 stop18h 31m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$320
This Expedia deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:05 am
CMH
- BOG
1 stop6h 50m
Spirit Airlines
Tue 3/1712:50 pm
BOG
- CMH
1 stop9h 29m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:40 am
CMH
- MDE
1 stop14h 41m
Spirit Airlines
Mon 3/231:17 am
MDE
- CMH
1 stop20h 32m
Spirit Airlines
Deal found 1/31![Spirit Airlines logo]()
$269
One-way flights from Columbus to South AmericaSearch for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated February 2, 2026.
Search for one-way flight options from Columbus to South America. Find affordable one-way fares based on user searches. Data last updated February 2, 2026.
This Orbitz deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:45 am
CMH
- BOG
1 stop7h 02m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:15 am
CMH
- BOG
1 stop7h 55m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$103
This Trip.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/145:43 pm
CMH
- BOG
1 stop19h 04m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:37 pm
CMH
- BOG
1 stop17h 10m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:45 am
CMH
- BOG
1 stop7h 02m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$115
This Cheapflightsfares deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:25 am
CMH
- MDE
1 stop7h 48m
Spirit Airlines
Deal found 1/31![Spirit Airlines logo]()
$123
This KAYAK deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:15 am
CMH
- BOG
1 stop7h 55m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:45 am
CMH
- BOG
1 stop7h 02m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:15 am
CMH
- BOG
2 stops11h 10m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:25 am
CMH
- MDE
2 stops16h 41m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:45 am
CMH
- BOG
1 stop7h 02m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$155
This Super.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/205:45 am
CMH
- LIM
1 stop16h 50m
Spirit Airlines
Deal found 2/2![Spirit Airlines logo]()
$173
Find flight deals from Columbus to South America
Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated February 2, 2026.
Round-trip from | $203 (Expedia) |
|---|---|
One-way from | $86 (Orbitz) |
Popular in | December |
Cheapest in | October |
Average price | $762 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
Use the filters below to find and compare flights from Columbus to South America that are best for you.
Fly from
Columbus
Fly to
South America
Route
Depart
Return
Price
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Tue 3/3
5:45 am-1:55 pm
1 stop8h 10m
Medellín Jose Maria Cordova Intl
Tue 3/10
2:15 pm-11:32 pm
1 stop8h 17m
$203
ColumbusLima
CMH - LIM
CMHLIM
Columbus
Mon 3/2
6:15 am-10:35 pm
1 stop16h 20m
Lima J Chavez Intl
Mon 3/9
10:30 pm-11:53 pm
2 stops24h 23m
$223
ColumbusGuayaquil
CMH - GYE
CMHGYE
Columbus
Mon 3/2
11:39 am-12:04 am
1 stop12h 25m
Guayaquil Jose Joaquin de Olmedo
Mon 3/9
11:59 pm-10:44 am
1 stop9h 45m
$254
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Tue 3/17
10:40 am-12:21 am
1 stop14h 41m
Medellín Jose Maria Cordova Intl
Mon 3/23
1:17 am-10:49 pm
1 stop20h 32m
$269
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Wed 4/1
10:40 am-12:21 am
1 stop14h 41m
Medellín Jose Maria Cordova Intl
Thu 4/9
2:17 pm-10:49 pm
1 stop7h 32m
$275
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Tue 3/3
7:37 pm-12:47 pm
1 stop17h 10m
Bogotá El Dorado
Wed 4/8
12:50 pm-11:19 pm
1 stop9h 29m
$305
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Tue 3/3
7:37 pm-12:47 pm
1 stop17h 10m
Bogotá El Dorado
Thu 4/9
12:50 pm-11:19 pm
1 stop9h 29m
$305
ColumbusBogotá
CMH - BOG
CMHBOG
Columbus
Wed 3/4
5:45 am-12:47 pm
1 stop7h 02m
Bogotá El Dorado
Thu 4/9
12:50 pm-11:19 pm
1 stop9h 29m
$311
ColumbusGuayaquil
CMH - GYE
CMHGYE
Columbus
Fri 2/20
10:54 am-12:04 am
2 stops37h 10m
Guayaquil Jose Joaquin de Olmedo
Mon 3/9
11:59 pm-10:44 am
1 stop9h 45m
$312
ColumbusMedellín
CMH - MDE
CMHMDE
Columbus
Wed 4/1
10:40 am-12:21 am
1 stop14h 41m
Medellín Jose Maria Cordova Intl
Fri 4/10
1:17 am-9:41 am
1 stop7h 24m
$313
Showing 1-10 of 60 results
Best time to book a flight from Columbus to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
CMH-BOG
CMH-MDE
CMH-LIM
CMH-GYE
CMH-CTG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus to South America
C01-0SA
CMH-BOG
CMH-MDE
CMH-LIM
CMH-GYE
What is the cheapest month to book a flight from Columbus to South America?
Currently, February is the cheapest month in which you can book a flight from Columbus to South America (average of $244). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 2, 2026.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Columbus to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.9
Boarding
8.1
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Boarding
8.1
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Boarding
8.1
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Boarding
8.1
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Boarding
8.1
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Boarding
8.1
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for Columbus to South America
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from Columbus to South America
Discover the top 5 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$244 | Average$376 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$443 | Average$764 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$552 | Average$829 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$562 | Average$803 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$744 | Average$956 | FlexibilityNo cancel fee | On-time67% |