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South America

$130+ Cheap flights from Columbus to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Find flight deals from Columbus to South America

Cheapest flights from Columbus to South America
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This CheapOair deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:00 amCMH - CTG
1 stop7h 25mSpirit Airlines
Thu 12/42:25 pmCTG - CMH
1 stop7h 49mSpirit Airlines
Deal found 10/15$306
This CheapOair deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/95:25 amCMH - CTG
1 stop7h 50mSpirit Airlines
Thu 11/132:20 pmCTG - CMH
1 stop8h 50mSpirit Airlines
Deal found 10/15$321
This Priceline deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:00 amCMH - CTG
1 stop7h 25mSpirit Airlines
Tue 12/22:30 pmCTG - CMH
1 stop9h 21mSpirit Airlines
Deal found 10/15$323
This KAYAK deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:30 amCMH - MDE
1 stop17h 27mSpirit Airlines
Fri 11/71:52 amMDE - CMH
1 stop21h 18mSpirit Airlines
Deal found 10/14$329
This Orbitz deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:00 amCMH - CTG
1 stop7h 25mSpirit Airlines
Tue 12/22:30 pmCTG - CMH
1 stop9h 21mSpirit Airlines
Deal found 10/15$340
This KAYAK deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/11:04 pmCMH - CTG
2 stops25h 11mSpirit Airlines
Fri 11/72:20 pmCTG - CMH
1 stop8h 50mSpirit Airlines
Deal found 10/15$346
This KAYAK deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:25 amCMH - MDE
1 stop19h 32mSpirit Airlines
Fri 11/213:14 pmMDE - CMH
1 stop8h 37mSpirit Airlines
Deal found 10/15$347
This Cheapflightsfares deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:30 amCMH - MDE
1 stop17h 27mSpirit Airlines
Sun 2/812:09 pmMDE - CMH
1 stop7h 56mSpirit Airlines
Deal found 10/15$352
This Travelocity deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:00 amCMH - CTG
1 stop7h 25mSpirit Airlines
Tue 12/22:30 pmCTG - CMH
1 stop9h 21mSpirit Airlines
Deal found 10/15$355
This Travelocity deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:00 amCMH - CTG
1 stop7h 25mSpirit Airlines
Sat 12/62:25 pmCTG - CMH
1 stop7h 49mSpirit Airlines
Deal found 10/15$356
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:30 amCMH - MDE
1 stop17h 27mMultiple Airlines
Sun 11/161:52 amMDE - CMH
2 stops13h 43mMultiple Airlines
Deal found 10/14$360
This Expedia deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/175:25 amCMH - CTG
1 stop7h 50mSpirit Airlines
Mon 11/242:30 pmCTG - CMH
1 stop9h 21mSpirit Airlines
Deal found 10/15$366

Cheap flight deals from Columbus to South America

Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated October 16, 2025.

Round-trip from

$306
(CheapOair)

One-way from

$130
(Kiwi.com)
From Columbus to South America
Search Deals
One-way flight from Columbus to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Columbus to South America that are best for you.

Fly from

Columbus

Fly to

South America

Route

Depart

Return

Price

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Sun 11/9

5:25 am-1:15 pm

1 stop7h 50m

Cartagena Rafael Nunez

Thu 11/13

2:20 pm-11:10 pm

1 stop8h 50m

$321

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Thu 11/13

5:25 am-12:57 am

1 stop19h 32m

Medellín Jose Maria Cordova Intl

Fri 11/21

3:14 pm-11:51 pm

1 stop8h 37m

$347

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 11/11

7:30 am-12:57 am

1 stop17h 27m

Medellín Jose Maria Cordova Intl

Sun 2/8

12:09 pm-8:05 pm

1 stop7h 56m

$352

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Thu 11/27

6:00 am-1:25 pm

1 stop7h 25m

Cartagena Rafael Nunez

Fri 12/5

2:25 pm-10:19 am

2 stops19h 54m

$426

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Wed 12/3

6:00 am-1:25 pm

1 stop7h 25m

Cartagena Rafael Nunez

Sun 12/7

2:25 pm-10:14 pm

1 stop7h 49m

$436

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Thu 11/13

9:42 am-12:57 am

2 stops15h 15m

Medellín Jose Maria Cordova Intl

Tue 11/18

3:14 pm-11:10 pm

1 stop7h 56m

$460

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Thu 11/13

5:25 am-12:57 am

1 stop19h 32m

Medellín Jose Maria Cordova Intl

Mon 11/17

6:43 am-3:23 pm

2 stops32h 40m

$470

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Tue 11/11

7:30 am-9:15 pm

2 stops13h 45m

Cartagena Rafael Nunez

Tue 11/18

5:40 am-11:10 pm

2 stops17h 30m

$480

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Wed 11/5

7:30 am-9:15 pm

2 stops13h 45m

Cartagena Rafael Nunez

Wed 11/12

6:50 am-11:10 pm

2 stops16h 20m

$484

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Wed 11/12

7:30 am-9:15 pm

2 stops13h 45m

Cartagena Rafael Nunez

Tue 11/18

5:40 am-11:10 pm

2 stops17h 30m

$490

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Showing 1-10 of 60 results
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Best time to book a flight from Columbus to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to South America

What is the cheapest month to book a flight from Columbus to South America?

Currently, February is the cheapest month in which you can book a flight from Columbus to South America (average of $257). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SA?

Find hourly flight availability from Columbus to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

It’s typically best to fly out from Columbus to South America in the evening. Doing so could potentially save you 14% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Columbus to South America?

Use this chart to determine the cheapest time to fly round-trip from Columbus to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Columbus to South America flight should consider departing on Tuesday mornings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated October 16, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and United Airlines from Columbus to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,979 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,979 reviews
Delta
7.9
Good
7,979 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
LATAM Airlines
7.5
Good
1,866 reviews
Delta
7.9
Good
7,979 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,982 reviews
Delta
7.9
Good
7,979 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
7,979 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Spirit Airlines
6.3
Okay
8,099 reviews
Delta
7.9
Good
7,979 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus to South America?

    For as low as $321, Spirit Airlines can have you in South America from Columbus in 7h 50m. There are 2090 mi between Columbus and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Columbus to South America?

    Most travelers choose Columbus - Cartagena Rafael Nunez, Columbus - Medellín Jose Maria Cordova Intl or Columbus - Rio de Janeiro–Galeão Intl when deciding on the best route from Columbus to South America.

  • Can I find deals for flights from Columbus to South America that include hotel bookings?

    Yes. In addition to deals on Columbus to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to South America.

  • Can I find deals for business class flights from Columbus to South America?

    Yes. Cheapflights offers flight deals from Columbus to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to South America?

    Currently, February is the cheapest month in which you can book a flight from Columbus to South America (average of $257). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Columbus to South America

Discover the top 6 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$261Average$430FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$423Average$764FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$534Average$940FlexibilityNo cancel feeOn-time69%
DeltaCheapest$539Average$849FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$555Average$819FlexibilityNo cancel feeOn-time81%
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

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