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South America

$116+ Cheap flights from Columbus to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Columbus to South America

Cheapest flights from Columbus to South America
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Expedia deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:15 am
CMH
-
MDE
1 stop7h 58m
Spirit Airlines
Thu 2/263:15 pm
MDE
-
CMH
1 stop8h 17m
Spirit Airlines
Deal found 1/26$247
This Cheapflightsfares deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:45 am
CMH
-
BOG
1 stop7h 02m
Spirit Airlines
Tue 3/31:45 pm
BOG
-
CMH
1 stop10h 08m
Spirit Airlines
Deal found 1/26$257
This Orbitz deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:45 am
CMH
-
BOG
1 stop7h 02m
Spirit Airlines
Wed 3/41:45 pm
BOG
-
CMH
1 stop10h 08m
Spirit Airlines
Deal found 1/27$262
This Expedia deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:15 am
CMH
-
CTG
1 stop6h 55m
Spirit Airlines
Tue 3/171:24 pm
CTG
-
CMH
1 stop8h 25m
Spirit Airlines
Deal found 1/26$282
This Travelocity deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:15 am
CMH
-
CTG
1 stop6h 55m
Spirit Airlines
Mon 3/91:21 pm
CTG
-
CMH
1 stop9h 11m
Spirit Airlines
Deal found 1/27$284
This Mytrip deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:15 am
CMH
-
MDE
2 stops12h 07m
Multiple Airlines
Thu 2/266:43 am
MDE
-
CMH
2 stops16h 49m
Multiple Airlines
Deal found 1/26$300
This Travelocity deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:15 am
CMH
-
CTG
1 stop6h 55m
Spirit Airlines
Mon 3/91:21 pm
CTG
-
CMH
1 stop9h 11m
Spirit Airlines
Deal found 1/27$300
This CheapOair deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:25 am
CMH
-
MDE
1 stop7h 48m
Spirit Airlines
Mon 4/201:37 am
MDE
-
CMH
1 stop19h 36m
Spirit Airlines
Deal found 1/28$308
This Orbitz deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:25 am
CMH
-
CTG
1 stop6h 48m
Spirit Airlines
Mon 4/271:21 pm
CTG
-
CMH
1 stop7h 52m
Spirit Airlines
Deal found 1/27$317
This CheapOair deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:25 am
CMH
-
MDE
1 stop7h 48m
Spirit Airlines
Sun 4/191:37 am
MDE
-
CMH
1 stop19h 36m
Spirit Airlines
Deal found 1/26$328
This CheapOair deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:15 am
CMH
-
CTG
1 stop6h 55m
Spirit Airlines
Sun 3/81:21 pm
CTG
-
CMH
1 stop20h 23m
Spirit Airlines
Deal found 1/27$328
This CheapOair deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:39 am
CMH
-
CTG
1 stop25h 31m
Spirit Airlines
Sun 3/81:21 pm
CTG
-
CMH
1 stop20h 23m
Spirit Airlines
Deal found 1/25$332

Find flight deals from Columbus to South America

Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated January 28, 2026.

Round-trip from

$247
(Expedia)

One-way from

$116
(Super.com)

Popular in

December

Cheapest in

October

Average price

$368
From Columbus to South America
Search Deals
One-way flight from Columbus to South America
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($155 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($39 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Columbus to South America that are best for you.

Fly from

Columbus

Fly to

South America

Route

Depart

Return

Price

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Wed 2/18

6:15 am-2:10 pm

1 stop7h 55m

Bogotá El Dorado

Wed 3/4

1:45 pm-11:53 pm

1 stop10h 08m

$262

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Sat 2/28

5:45 am-12:47 pm

1 stop7h 02m

Bogotá El Dorado

Tue 3/3

1:45 pm-10:44 am

2 stops20h 59m

$274

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Mon 2/16

11:39 am-1:55 pm

2 stops26h 16m

Medellín Jose Maria Cordova Intl

Thu 2/26

3:15 pm-11:32 pm

1 stop8h 17m

$288

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Mon 2/16

6:15 am-6:22 pm

2 stops12h 07m

Medellín Jose Maria Cordova Intl

Thu 2/26

6:43 am-11:32 pm

2 stops16h 49m

$300

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 4/15

6:25 am-1:13 pm

1 stop7h 48m

Medellín Jose Maria Cordova Intl

Mon 4/20

1:37 am-10:13 pm

1 stop19h 36m

$308

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Wed 4/22

6:25 am-12:13 pm

1 stop6h 48m

Cartagena Rafael Nunez

Mon 4/27

1:21 pm-10:13 pm

1 stop7h 52m

$317

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 4/15

6:25 am-1:13 pm

1 stop7h 48m

Medellín Jose Maria Cordova Intl

Sun 4/19

1:37 am-10:13 pm

1 stop19h 36m

$328

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Tue 3/3

6:15 am-1:10 pm

1 stop6h 55m

Cartagena Rafael Nunez

Sun 3/8

1:21 pm-10:44 am

1 stop20h 23m

$328

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Wed 3/4

11:39 am-1:10 pm

1 stop25h 31m

Cartagena Rafael Nunez

Sun 3/8

1:21 pm-10:44 am

1 stop20h 23m

$332

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Thu 4/2

5:15 am-12:19 pm

1 stop8h 04m

Cartagena Rafael Nunez

Tue 4/7

1:24 pm-10:49 pm

1 stop8h 25m

$341

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 60 results
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Best time to book a flight from Columbus to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to South America

What is the cheapest month to book a flight from Columbus to South America?

Currently, February is the cheapest month in which you can book a flight from Columbus to South America (average of $244). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 28, 2026.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Columbus to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,122 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,122 reviews
Delta
7.9
Good
8,122 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,915 reviews
Delta
7.9
Good
8,122 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,200 reviews
Delta
7.9
Good
8,122 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Air Canada
7.1
Good
10,664 reviews
Delta
7.9
Good
8,122 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,383 reviews
Delta
7.9
Good
8,122 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus to South America?

    For as low as $262, Spirit Airlines can have you in South America from Columbus in 7h 55m. There are 2497 mi between Columbus and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Columbus to South America?

    Most travelers choose Columbus - Lima J Chavez Intl, Columbus - Cartagena Rafael Nunez or Columbus - Medellín Jose Maria Cordova Intl when deciding on the best route from Columbus to South America.

  • Can I find deals for flights from Columbus to South America that include hotel bookings?

    Yes. In addition to deals on Columbus to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to South America.

  • Can I find deals for business class flights from Columbus to South America?

    Yes. Cheapflights offers flight deals from Columbus to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to South America?

    Currently, February is the cheapest month in which you can book a flight from Columbus to South America (average of $244). Flying from Columbus to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Columbus to South America

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Top 5 airlines flying from Columbus to South America

Discover the top 5 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$244Average$376FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$443Average$764FlexibilityNo cancel feeOn-time71%
DeltaCheapest$552Average$869FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$562Average$812FlexibilityNo cancel feeOn-time81%
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

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