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South America

$119+ Cheap flights from Columbus to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Columbus to South America

Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated September 15, 2025.

Round-trip from

$282
(Expedia)

One-way from

$119
(Travelocity)
From Columbus to South America
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One-way flight from Columbus to South America
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Find flight deals from Columbus to South America

Cheapest flights from Columbus to South America
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:00 amCMH - BOG
1 stop9h 15mSpirit Airlines
Thu 11/61:57 pmBOG - CMH
1 stop18h 18mSpirit Airlines
Deal found 9/15$282
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:00 amCMH - MDE
1 stop9h 11mSpirit Airlines
Fri 10/241:16 amMDE - CMH
1 stop9h 42mSpirit Airlines
Deal found 9/13$291
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:15 amCMH - MDE
1 stop8h 59mSpirit Airlines
Wed 10/11:24 amMDE - CMH
1 stop9h 17mSpirit Airlines
Deal found 9/14$309
This Spirit Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/84:08 pmCMH - CTG
2 stops21h 00mSpirit Airlines
Tue 11/112:16 pmCTG - CMH
1 stop6h 56mSpirit Airlines
Deal found 9/13$313
This KAYAK deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:00 amCMH - MDE
1 stop9h 11mSpirit Airlines
Thu 10/302:22 pmMDE - CMH
1 stop20h 36mSpirit Airlines
Deal found 9/14$336
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:45 amCMH - MDE
1 stop11h 19mSpirit Airlines
Tue 12/96:59 pmMDE - CMH
1 stop14h 56mSpirit Airlines
Deal found 9/14$348
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:00 amCMH - BOG
1 stop9h 15mSpirit Airlines
Mon 10/132:10 pmBOG - CMH
2 stops23h 19mSpirit Airlines
Deal found 9/14$352
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:16 pmCMH - BOG
1 stop17h 44mSpirit Airlines
Sat 10/112:10 pmBOG - CMH
2 stops20h 13mSpirit Airlines
Deal found 9/14$354
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/245:15 amCMH - BOG
1 stop8h 55mSpirit Airlines
Sat 10/112:10 pmBOG - CMH
2 stops20h 13mSpirit Airlines
Deal found 9/14$362
This CheapOair deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:45 amCMH - CTG
1 stop6h 23mSpirit Airlines
Mon 11/102:16 pmCTG - CMH
1 stop6h 56mSpirit Airlines
Deal found 9/13$363
This KAYAK deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/148:42 amCMH - MDE
2 stops40h 39mSpirit Airlines
Wed 10/221:59 pmMDE - CMH
2 stops20h 59mSpirit Airlines
Deal found 9/15$364
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:49 pmCMH - MDE
1 stop20h 14mMultiple Airlines
Wed 12/1012:09 pmMDE - CMH
1 stop20h 47mMultiple Airlines
Deal found 9/14$371

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Columbus to South America that are best for you.

Fly from

Columbus

Fly to

South America

Route

Depart

Return

Price

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Thu 10/9

5:00 am-1:11 pm

1 stop9h 11m

Medellín Jose Maria Cordova Intl

Fri 10/24

1:16 am-11:58 am

1 stop9h 42m

$291

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Thu 10/9

5:00 am-1:11 pm

1 stop9h 11m

Medellín Jose Maria Cordova Intl

Wed 10/29

1:16 am-11:58 am

1 stop9h 42m

$291

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Sat 11/8

4:08 pm-1:08 pm

2 stops21h 00m

Cartagena Rafael Nunez

Tue 11/11

2:16 pm-9:12 pm

1 stop6h 56m

$313

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Thu 10/30

5:00 am-1:15 pm

1 stop9h 15m

Bogotá El Dorado

Thu 11/6

3:05 pm-7:41 am

2 stops16h 36m

$339

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Mon 10/6

12:28 pm-7:25 pm

1 stop7h 57m

Bogotá El Dorado

Mon 10/13

9:20 am-2:29 pm

1 stop28h 09m

$368

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Tue 10/14

8:19 pm-12:21 am

2 stops29h 02m

Medellín Jose Maria Cordova Intl

Tue 10/21

1:16 am-2:29 pm

2 stops12h 13m

$384

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Wed 10/8

8:42 am-12:21 am

2 stops16h 39m

Medellín Jose Maria Cordova Intl

Wed 10/29

1:16 am-11:58 am

1 stop9h 42m

$398

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Thu 11/6

5:22 pm-1:08 pm

2 stops19h 46m

Cartagena Rafael Nunez

Tue 11/11

2:16 pm-9:12 pm

1 stop6h 56m

$398

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Wed 9/24

5:15 am-1:10 pm

1 stop8h 55m

Bogotá El Dorado

Sat 10/11

2:10 pm-11:58 am

1 stop20h 48m

$399

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

Mon 10/6

5:00 am-12:25 pm

1 stop8h 25m

Cartagena Rafael Nunez

Wed 10/15

8:46 am-11:58 am

3 stops26h 12m

$406

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 60 results
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Best time to book a flight from Columbus to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to South America

What is the cheapest month to book a flight from Columbus to South America?

Currently, May is the cheapest month in which you can book a flight from Columbus to South America (average of $359). Flying from Columbus to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SA?

Find hourly flight availability from Columbus to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Columbus to South America as you normally would.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 15, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and United Airlines from Columbus to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,929 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Spirit Airlines
6.3
Okay
8,015 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus to South America?

    For as low as $291, Spirit Airlines can have you in South America from Columbus in 9h 11m. There are 2382 mi between Columbus and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Columbus to South America?

    Most travelers choose Columbus - Medellín Jose Maria Cordova Intl, Columbus - Cartagena Rafael Nunez or Columbus - Buenos Aires Ministro Pistarini when deciding on the best route from Columbus to South America.

  • Can I find deals for flights from Columbus to South America that include hotel bookings?

    Yes. In addition to deals on Columbus to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to South America.

  • Can I find deals for business class flights from Columbus to South America?

    Yes. Cheapflights offers flight deals from Columbus to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to South America?

    Currently, May is the cheapest month in which you can book a flight from Columbus to South America (average of $359). Flying from Columbus to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Columbus to South America

Discover the top 6 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$261Average$431FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$370Average$871FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$423Average$774FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$534Average$926FlexibilityNo cancel feeOn-time69%
DeltaCheapest$539Average$925FlexibilityNo cancel feeOn-timeN/A
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

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