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South America

$172+ Cheap flights from Columbus to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — BOG
jan 16 — jan 231
sex 1/16
sex 1/23
1 adult, Economy
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Cheap flight deals from Columbus to South America

Cheapest flights from Columbus to South America
Explore the most affordable flight options available from Columbus to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on dezembro 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/316:28 pmCMH - BOG
1 stop18h 24mSpirit Airlines
seg 1/193:06 pmBOG - CMH
2 stops32h 13mSpirit Airlines
Deal found 12/14$483
This Mytrip deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/316:28 pmCMH - BOG
3 stops29h 27mMultiple Airlines
seg 1/193:06 pmBOG - CMH
3 stops32h 13mMultiple Airlines
Deal found 12/14$567
This Orbitz deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/316:28 pmCMH - BOG
1 stop18h 24mSpirit Airlines
ter 1/62:17 amBOG - CMH
1 stop20h 21mSpirit Airlines
Deal found 12/14$584
This Orbitz deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/1711:14 amCMH - MDE
1 stop23h 41mSpirit Airlines
qua 12/242:25 amMDE - CMH
1 stop15h 08mSpirit Airlines
Deal found 12/16$670
This Cheapflightsfares deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/168:00 pmCMH - MDE
2 stops17h 55mAvianca
sex 12/262:10 pmMDE - CMH
2 stops19h 39mAvianca
Deal found 12/16$682
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/316:28 pmCMH - BOG
1 stop18h 24mMultiple Airlines
qua 1/78:26 amBOG - CMH
2 stops25h 14mMultiple Airlines
Deal found 12/14$699
This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 12/1911:14 amCMH - BOG
1 stop13h 58mSpirit Airlines
dom 1/253:06 pmBOG - CMH
1 stop18h 34mSpirit Airlines
Deal found 12/15$708
This Copa Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/1710:30 amCMH - MDE
2 stops21h 48mCopa Airlines
qui 12/258:37 amMDE - CMH
2 stops25h 12mCopa Airlines
Deal found 12/16$711
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/1611:14 amCMH - BOG
2 stops42h 26mMultiple Airlines
ter 1/133:06 pmBOG - CMH
1 stop8h 21mMultiple Airlines
Deal found 12/14$730
This KAYAK deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 12/227:00 amCMH - BOG
2 stops11h 40mLATAM Airlines
seg 12/293:55 pmBOG - CMH
1 stop8h 18mLATAM Airlines
Deal found 12/15$733
This Orbitz deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/314:00 pmCMH - BOG
2 stops24h 45mLATAM Airlines
qua 1/76:15 amBOG - CMH
2 stops17h 46mLATAM Airlines
Deal found 12/14$739
This Travelocity deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/1611:14 amCMH - MDE
1 stop23h 41mSpirit Airlines
qui 12/252:25 amMDE - CMH
1 stop15h 08mSpirit Airlines
Deal found 12/16$742

Find flight deals from Columbus to South America

Keep the following information in mind while searching for Columbus to South America flight deals. Data was last updated dezembro 17, 2025.

Round-trip from

$265
(Priceline)

One-way from

$172
(Mytrip)
From Columbus to South America
Search Deals
One-way flight from Columbus to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated dezembro 17, 2025.
Use the filters below to find and compare flights from Columbus to South America that are best for you.

Fly from

Columbus

Fly to

South America

Route

Depart

Return

Price

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

sáb 1/31

5:45 am-2:15 pm

1 stop8h 30m

Medellín Jose Maria Cordova Intl

sáb 2/7

3:15 pm-11:27 pm

1 stop8h 12m

$305

ColumbusLima

CMH - LIM

CMHLIM

Columbus

qua 1/28

5:45 am-10:35 pm

1 stop16h 50m

Lima J Chavez Intl

seg 2/2

11:33 pm-11:27 pm

1 stop23h 54m

$353

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

qui 2/19

5:40 am-1:55 pm

1 stop8h 15m

Medellín Jose Maria Cordova Intl

ter 2/24

3:15 pm-11:32 pm

1 stop8h 17m

$357

ColumbusLima

CMH - LIM

CMHLIM

Columbus

qui 1/22

10:40 am-10:35 pm

1 stop11h 55m

Lima J Chavez Intl

qui 1/29

11:33 pm-9:40 am

1 stop10h 07m

$368

ColumbusCartagena

CMH - CTG

CMHCTG

Columbus

sex 2/6

5:45 am-1:15 pm

1 stop7h 30m

Cartagena Rafael Nunez

seg 2/9

2:21 pm-11:27 pm

1 stop9h 06m

$368

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

sáb 1/31

5:45 am-2:07 pm

1 stop8h 22m

Bogotá El Dorado

sáb 2/7

1:45 pm-11:19 pm

1 stop9h 34m

$374

ColumbusLima

CMH - LIM

CMHLIM

Columbus

qua 1/21

5:45 am-10:35 pm

1 stop16h 50m

Lima J Chavez Intl

qua 1/28

11:33 pm-11:27 pm

1 stop23h 54m

$378

ColumbusLima

CMH - LIM

CMHLIM

Columbus

seg 1/19

10:40 am-10:35 pm

1 stop11h 55m

Lima J Chavez Intl

ter 1/27

11:33 pm-11:19 pm

2 stops23h 46m

$393

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

qui 2/5

6:06 am-12:50 pm

1 stop30h 44m

Bogotá El Dorado

qui 2/12

1:45 pm-11:53 pm

1 stop10h 08m

$393

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

sáb 1/31

5:45 am-7:36 pm

2 stops13h 51m

Medellín Jose Maria Cordova Intl

sáb 2/7

3:15 pm-11:27 pm

1 stop8h 12m

$396

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 60 results
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Best time to book a flight from Columbus to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to South America

What is the cheapest month to book a flight from Columbus to South America?

Currently, March is the cheapest month in which you can book a flight from Columbus to South America (average of $277). Flying from Columbus to South America in June is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to SA?

Find hourly flight availability from Columbus to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated dezembro 17, 2025.

It’s typically best to fly out from Columbus to South America in the morning. Doing so could potentially save you 7% on the flight price compared to flying in the afternoon, which is usually more expensive.

What is the cheapest day to fly from Columbus to South America?

Use this chart to determine the cheapest time to fly round-trip from Columbus to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Columbus to South America flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated dezembro 17, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and American Airlines from Columbus to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,892 reviews
Delta
7.9
Good
8,005 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,005 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Air Canada
7.1
Good
10,534 reviews
Delta
7.9
Good
8,005 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,190 reviews
Delta
7.9
Good
8,005 reviews

Comfort

7.9

Boarding

8.1

Food

7.3

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus to South America?

    For as low as $305, Spirit Airlines can have you in South America from Columbus in 8h 30m. There are 2382 mi between Columbus and South America. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Columbus to South America?

    Most travelers choose Columbus - Medellín Jose Maria Cordova Intl, Columbus - Lima J Chavez Intl or Columbus - Sao Paulo Guarulhos Intl when deciding on the best route from Columbus to South America.

  • Can I find deals for flights from Columbus to South America that include hotel bookings?

    Yes. In addition to deals on Columbus to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to South America.

  • Can I find deals for business class flights from Columbus to South America?

    Yes. Cheapflights offers flight deals from Columbus to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to South America?

    Currently, March is the cheapest month in which you can book a flight from Columbus to South America (average of $277). Flying from Columbus to South America in June is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Columbus to South America

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Top 6 airlines flying from Columbus to South America

Discover the top 6 airlines that operate flights from Columbus to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated dezembro 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$276Average$406FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$490Average$717FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$534Average$613FlexibilityNo cancel feeOn-time69%
DeltaCheapest$552Average$863FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$555Average$821FlexibilityNo cancel feeOn-time81%
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

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