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South America

$156+ Cheap flights from Buffalo (BUF) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — BOG
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Buffalo to South America

Cheapest flights from Buffalo to South America
Explore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/111:57 amBUF - BOG
1 stop25h 03mMultiple Airlines
Thu 12/181:47 pmBOG - BUF
1 stop30h 53mMultiple Airlines
Deal found 10/28$314
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2811:52 amBUF - BOG
1 stop25h 08mMultiple Airlines
Thu 12/181:47 pmBOG - BUF
1 stop30h 53mMultiple Airlines
Deal found 10/28$325
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/111:57 amBUF - BOG
1 stop25h 03mMultiple Airlines
Wed 12/171:47 pmBOG - BUF
1 stop23h 25mMultiple Airlines
Deal found 10/28$346
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2811:52 amBUF - BOG
1 stop25h 08mMultiple Airlines
Wed 12/171:47 pmBOG - BUF
1 stop23h 25mMultiple Airlines
Deal found 10/28$357
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/111:57 amBUF - BOG
1 stop25h 03mMultiple Airlines
Tue 12/169:48 pmBOG - BUF
2 stops39h 24mMultiple Airlines
Deal found 10/28$375
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/111:57 amBUF - BOG
1 stop25h 03mMultiple Airlines
Sun 12/141:47 pmBOG - BUF
2 stops20h 58mMultiple Airlines
Deal found 10/28$378
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:08 amBUF - BOG
1 stop25h 44mMultiple Airlines
Tue 12/301:47 pmBOG - BUF
1 stop30h 53mMultiple Airlines
Deal found 10/26$384
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2811:52 amBUF - BOG
1 stop25h 08mMultiple Airlines
Tue 12/169:48 pmBOG - BUF
2 stops39h 24mMultiple Airlines
Deal found 10/28$386
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2811:52 amBUF - BOG
1 stop25h 08mMultiple Airlines
Sun 12/141:47 pmBOG - BUF
2 stops20h 58mMultiple Airlines
Deal found 10/28$389
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/111:57 amBUF - BOG
1 stop25h 03mMultiple Airlines
Fri 12/121:47 pmBOG - BUF
1 stop24h 28mMultiple Airlines
Deal found 10/28$391
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1212:37 pmBUF - MDE
1 stop22h 18mMultiple Airlines
Fri 12/1911:50 amMDE - BUF
1 stop8h 50mMultiple Airlines
Deal found 10/28$422
This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:19 pmBUF - MDE
2 stops20h 18mJetBlue
Tue 12/162:04 pmMDE - BUF
1 stop27h 06mJetBlue
Deal found 10/28$583

Cheap flight deals from Buffalo to South America

Keep the following information in mind while searching for Buffalo to South America flight deals. Data was last updated October 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$314
(Kiwi.com)

One-way from

$156
(Kiwi.com)
Provider with most accurate pricing for Buffalo-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Sao Paulo (SAO) flights.
Search Deals
From Buffalo to South America
Search Deals
One-way flight from Buffalo to South America
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Buffalo to South America that are best for you.

Fly from

Buffalo

Fly to

South America

Route

Depart

Return

Price

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

Mon 1/12

5:35 pm-2:17 pm

2 stops20h 42m

Cartagena Rafael Nunez

Thu 1/15

3:32 pm-10:59 pm

2 stops31h 27m

$394

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

Sun 1/11

5:44 pm-2:17 pm

2 stops20h 33m

Cartagena Rafael Nunez

Fri 1/16

3:32 pm-11:24 am

2 stops43h 52m

$394

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

Sun 1/11

5:35 pm-2:17 pm

2 stops20h 42m

Cartagena Rafael Nunez

Thu 1/15

3:32 pm-10:59 pm

2 stops31h 27m

$394

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

Thu 1/8

6:38 pm-2:17 pm

1 stop19h 39m

Cartagena Rafael Nunez

Thu 1/15

3:32 pm-10:59 pm

2 stops31h 27m

$394

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

Thu 1/8

2:54 pm-2:17 pm

2 stops23h 23m

Cartagena Rafael Nunez

Fri 1/16

3:32 pm-11:24 am

2 stops43h 52m

$394

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Mon 12/1

11:57 am-1:00 pm

1 stop25h 03m

Bogotá El Dorado

Sun 12/14

1:47 pm-2:15 pm

1 stop24h 28m

$397

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

Sun 3/22

6:00 am-1:15 pm

1 stop8h 15m

Cartagena Rafael Nunez

Thu 3/26

2:30 pm-11:57 pm

1 stop8h 27m

$398

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

Wed 1/7

5:35 pm-2:17 pm

2 stops44h 42m

Cartagena Rafael Nunez

Thu 1/15

3:32 pm-10:59 pm

2 stops31h 27m

$400

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

Sat 1/10

2:10 pm-2:17 pm

1 stop24h 07m

Cartagena Rafael Nunez

Fri 1/16

3:32 pm-10:59 pm

2 stops31h 27m

$401

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

Mon 1/12

6:38 pm-2:17 pm

1 stop19h 39m

Cartagena Rafael Nunez

Fri 1/16

3:32 pm-10:59 pm

2 stops31h 27m

$401

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 60 results
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Best time to book a flight from Buffalo to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South America

What is the cheapest month to book a flight from Buffalo to South America?

Currently, March is the cheapest month in which you can book a flight from Buffalo to South America (average of $282). Flying from Buffalo to South America in October is currently the most expensive (average of $537). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SA?

Find hourly flight availability from Buffalo to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

It’s typically best to fly out from Buffalo to South America in the morning. Doing so could potentially save you 30% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated October 29, 2025.
Get a feel of what it's like to fly with Delta and LATAM Airlines from Buffalo to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,994 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
7,994 reviews
Delta
7.9
Good
7,994 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
LATAM Airlines
7.5
Good
1,871 reviews
Delta
7.9
Good
7,994 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to South America?

    Buffalo (BUF) is the airport you will fly out of if you book a flight from Buffalo to South America. It is only a 8.3 mi journey to Buffalo (BUF) from Buffalo’s city center.

  • How long is the flight from Buffalo to South America?

    Departing from Buffalo to South America will take you 14h 30m. Buffalo and South America are separated by a distance of 2655 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Buffalo to South America one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $224. However, be on the lookout for offers from Delta and LATAM Airlines, as they are both options that can get you from Buffalo to South America for a low price.

  • What are the most popular routes from Buffalo to South America?

    While some choose either Buffalo - Medellín Jose Maria Cordova Intl or Buffalo - Buenos Aires Ministro Pistarini, Buffalo - Bogotá El Dorado is the most popular route from Buffalo to South America.

  • Can I find deals for flights from Buffalo to South America that include hotel bookings?

    Yes. In addition to deals on Buffalo to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South America.

  • Can I find deals for business class flights from Buffalo to South America?

    Yes. Cheapflights offers flight deals from Buffalo to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to South America?

    Currently, March is the cheapest month in which you can book a flight from Buffalo to South America (average of $282). Flying from Buffalo to South America in October is currently the most expensive (average of $537). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Buffalo to South America

Discover the top 2 airlines that operate flights from Buffalo to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$451Average$668FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$494Average$904FlexibilityNo cancel feeOn-time81%

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