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South America

$175+ Cheap flights from Buffalo (BUF) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — BOG
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Buffalo to South America

Keep the following information in mind while searching for Buffalo to South America flight deals. Data was last updated September 11, 2025.

Round-trip from

$436
(Expedia)

One-way from

$175
(Kiwi.com)
From Buffalo to South America
Search Deals
One-way flight from Buffalo to South America
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Find flight deals from Buffalo to South America

Cheapest flights from Buffalo to South America
Explore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2610:05 amBUF - CTG
1 stop28h 04mJetBlue
Sun 11/23:30 pmCTG - BUF
1 stop17h 50mJetBlue
Deal found 9/10$436
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:00 amBUF - BOG
1 stop17h 20mAmerican Airlines
Mon 11/1011:55 pmBOG - BUF
1 stop16h 17mAmerican Airlines
Deal found 9/10$473
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:50 pmBUF - BOG
2 stops21h 55mDelta
Mon 11/109:00 amBOG - BUF
1 stop14h 50mDelta
Deal found 9/10$477
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/119:45 pmBUF - MDE
1 stop16h 19mMultiple Airlines
Fri 10/171:16 amMDE - BUF
2 stops33h 03mMultiple Airlines
Deal found 9/11$506
This Ovago deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:40 amBUF - MDE
1 stop7h 52mJetBlue
Sun 11/232:25 pmMDE - BUF
1 stop29h 37mJetBlue
Deal found 9/10$528
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:50 amBUF - MDE
2 stops21h 59mCopa Airlines
Sun 11/235:00 amMDE - BUF
2 stops16h 00mCopa Airlines
Deal found 9/10$535
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/12:55 pmBUF - BOG
2 stops32h 40mUnited Airlines
Sun 11/91:30 amBOG - BUF
2 stops32h 33mUnited Airlines
Deal found 9/10$540
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/106:00 amBUF - BOG
2 stops16h 17mAmerican Airlines
Mon 10/136:30 amBOG - BUF
2 stops16h 12mAmerican Airlines
Deal found 9/11$543
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:55 pmBUF - MDE
2 stops28h 15mUnited Airlines
Fri 10/179:45 amMDE - BUF
2 stops26h 37mUnited Airlines
Deal found 9/10$565
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/267:38 pmBUF - CTG
2 stops17h 47mAmerican Airlines
Sun 11/24:30 pmCTG - BUF
2 stops19h 37mAmerican Airlines
Deal found 9/10$589
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/106:00 amBUF - MDE
2 stops15h 15mAmerican Airlines
Mon 10/136:00 amMDE - BUF
2 stops16h 42mAmerican Airlines
Deal found 9/10$627
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/245:24 pmBUF - LIM
2 stops22h 11mMultiple Airlines
Fri 10/318:25 amLIM - BUF
1 stop32h 52mMultiple Airlines
Deal found 9/9$649

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Buffalo to South America that are best for you.

Fly from

Buffalo

Fly to

South America

Route

Depart

Return

Price

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

Sun 10/26

10:05 am-1:09 pm

1 stop28h 04m

Cartagena Rafael Nunez

Sun 11/2

3:30 pm-9:20 am

1 stop17h 50m

$436

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Sat 11/1

6:20 am-7:30 pm

2 stops14h 10m

Bogotá El Dorado

Mon 11/10

3:55 pm-12:31 pm

2 stops20h 36m

$477

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Sat 10/11

9:45 pm-1:04 pm

1 stop16h 19m

Medellín Jose Maria Cordova Intl

Fri 10/17

1:16 am-11:19 am

2 stops33h 03m

$506

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Sat 1/10

8:20 pm-6:15 am

1 stop9h 55m

Bogotá El Dorado

Sat 1/17

7:05 am-7:21 pm

1 stop12h 16m

$528

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Thu 11/13

6:40 am-2:32 pm

1 stop7h 52m

Medellín Jose Maria Cordova Intl

Sun 11/23

2:25 pm-8:02 pm

1 stop29h 37m

$528

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Thu 11/13

10:50 am-8:49 am

2 stops21h 59m

Medellín Jose Maria Cordova Intl

Sun 11/23

5:00 am-9:00 pm

2 stops16h 00m

$535

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Sat 11/1

2:55 pm-10:35 pm

2 stops32h 40m

Bogotá El Dorado

Sun 11/9

1:30 am-10:03 am

2 stops32h 33m

$540

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Mon 1/5

6:10 am-1:20 pm

2 stops31h 10m

Medellín Jose Maria Cordova Intl

Thu 2/5

2:25 pm-11:38 pm

1 stop9h 13m

$551

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Mon 1/5

6:00 am-9:10 pm

2 stops15h 10m

Medellín Jose Maria Cordova Intl

Thu 2/5

6:50 am-10:26 pm

2 stops15h 36m

$564

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Thu 11/13

11:34 am-9:10 pm

2 stops9h 36m

Medellín Jose Maria Cordova Intl

Sun 11/23

3:10 pm-12:07 pm

2 stops20h 57m

$565

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 50 results
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Best time to book a flight from Buffalo to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South America

What is the cheapest month to book a flight from Buffalo to South America?

Currently, May is the cheapest month in which you can book a flight from Buffalo to South America (average of $359). Flying from Buffalo to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SA?

Find hourly flight availability from Buffalo to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Buffalo to South America as you normally would.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with Delta, LATAM Airlines, and United Airlines from Buffalo to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to South America?

    Buffalo (BUF) is the airport you will fly out of if you book a flight from Buffalo to South America. It is only a 8.3 mi journey to Buffalo (BUF) from Buffalo’s city center.

  • How long is the flight from Buffalo to South America?

    Departing from Buffalo to South America will take you 14h 10m. Buffalo and South America are separated by a distance of 2655 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Buffalo to South America?

    While some choose either Buffalo - Buenos Aires Ministro Pistarini or Buffalo - Medellín Jose Maria Cordova Intl, Buffalo - Buenos Aires Jorge Newbery is the most popular route from Buffalo to South America.

  • Can I find deals for flights from Buffalo to South America that include hotel bookings?

    Yes. In addition to deals on Buffalo to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South America.

  • Can I find deals for business class flights from Buffalo to South America?

    Yes. Cheapflights offers flight deals from Buffalo to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to South America?

    Currently, May is the cheapest month in which you can book a flight from Buffalo to South America (average of $359). Flying from Buffalo to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Buffalo to South America

Discover the top 3 airlines that operate flights from Buffalo to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$423Average$666FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$477Average$831FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$757Average$996FlexibilityNo cancel feeOn-time69%

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