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South America

$124+ Cheap flights from Buffalo (BUF) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — BOG
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
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Cheap flight deals from Buffalo to South America

Cheapest flights from Buffalo to South America
Explore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/117:27 amBUF - MDE
2 stops16h 12mAmerican Airlines
mar. 12/167:00 amMDE - BUF
2 stops15h 57mAmerican Airlines
Deal found 12/9$559
This Expedia deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/116:45 amBUF - MDE
1 stop7h 52mJetBlue
mar. 12/162:04 pmMDE - BUF
2 stops21h 30mJetBlue
Deal found 12/9$671
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/117:00 amBUF - MDE
2 stops22h 42mUnited Airlines
lun. 12/151:15 amMDE - BUF
2 stops13h 07mUnited Airlines
Deal found 12/10$732
This Expedia deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/118:00 amBUF - MDE
1 stop8h 00mMultiple Airlines
mar. 12/164:45 pmMDE - BUF
1 stop18h 49mMultiple Airlines
Deal found 12/9$757
This Copa Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/1510:10 amBUF - GIG
2 stops19h 50mCopa Airlines
sáb. 2/141:40 amGIG - BUF
2 stops21h 21mCopa Airlines
Deal found 12/11$1,194
This FlightHub deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/156:45 amBUF - GIG
2 stops48h 15mMultiple Airlines
dom. 2/155:30 pmGIG - BUF
2 stops52h 26mMultiple Airlines
Deal found 12/10$1,341
This FlightHub deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/143:55 pmBUF - EZE
1 stop16h 20mLATAM Airlines
mar. 12/1612:15 pmEZE - BUF
2 stops24h 49mLATAM Airlines
Deal found 12/10$1,640
This Expedia deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/241:55 pmBUF - LIM
2 stops34h 55mMultiple Airlines
sáb. 1/38:00 amLIM - BUF
2 stops15h 47mMultiple Airlines
Deal found 12/10$1,649
This KAYAK deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/156:00 amBUF - GIG
2 stops23h 10mLATAM Airlines
dom. 2/159:30 pmGIG - BUF
1 stop15h 48mLATAM Airlines
Deal found 12/11$1,665
This Copa Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/1410:10 amBUF - EZE
2 stops19h 49mCopa Airlines
mar. 12/162:32 pmEZE - BUF
2 stops32h 35mCopa Airlines
Deal found 12/10$1,688
This Ovago deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/226:54 pmBUF - LIM
2 stops25h 21mLATAM Airlines
lun. 1/53:55 pmLIM - BUF
2 stops45h 19mLATAM Airlines
Deal found 12/10$1,788
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/226:00 amBUF - LIM
2 stops15h 30mAmerican Airlines
lun. 1/510:55 pmLIM - BUF
2 stops16h 22mAmerican Airlines
Deal found 12/11$1,859

Find flight deals from Buffalo to South America

Keep the following information in mind while searching for Buffalo to South America flight deals. Data was last updated diciembre 12, 2025.

Round-trip from

$268
(JetBlue)

One-way from

$124
(American Airlines)

Popular in

June

Cheapest in

December

Average price

$219
From Buffalo to South America
Search Deals
One-way flight from Buffalo to South America
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($158 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from Buffalo to South America that are best for you.

Fly from

Buffalo

Fly to

South America

Route

Depart

Return

Price

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

lun. 2/2

6:00 am-2:50 pm

1 stop8h 50m

Cartagena Rafael Nunez

jue. 2/5

2:20 pm-11:47 pm

1 stop9h 27m

$268

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

vie. 2/20

5:24 pm-10:05 pm

2 stops28h 41m

Medellín Jose Maria Cordova Intl

mié. 2/25

10:45 am-11:44 pm

2 stops12h 59m

$308

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

dom. 1/25

6:00 am-2:50 pm

1 stop8h 50m

Cartagena Rafael Nunez

vie. 1/30

2:20 pm-11:47 pm

1 stop9h 27m

$313

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

dom. 1/25

6:00 am-2:50 pm

1 stop8h 50m

Cartagena Rafael Nunez

sáb. 1/31

2:20 pm-11:47 pm

1 stop9h 27m

$330

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

vie. 1/23

6:00 am-2:50 pm

1 stop8h 50m

Cartagena Rafael Nunez

vie. 1/30

2:20 pm-11:47 pm

1 stop9h 27m

$358

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

lun. 2/23

4:25 pm-2:06 pm

2 stops21h 41m

Medellín Jose Maria Cordova Intl

lun. 3/2

3:10 pm-10:59 am

2 stops19h 49m

$384

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

jue. 1/22

1:39 pm-12:50 pm

2 stops23h 11m

Bogotá El Dorado

jue. 1/29

1:45 pm-6:36 pm

1 stop28h 51m

$385

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

vie. 1/23

5:45 pm-2:17 pm

2 stops20h 32m

Cartagena Rafael Nunez

sáb. 1/31

3:32 pm-11:11 am

2 stops19h 39m

$387

BuffaloCartagena

BUF - CTG

BUFCTG

Buffalo

sáb. 1/24

3:43 pm-2:17 pm

2 stops22h 34m

Cartagena Rafael Nunez

vie. 1/30

3:32 pm-11:28 pm

1 stop7h 56m

$387

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

lun. 2/2

8:30 am-10:05 pm

2 stops37h 35m

Medellín Jose Maria Cordova Intl

jue. 2/5

10:45 am-8:29 pm

2 stops33h 44m

$404

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 60 results
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Best time to book a flight from Buffalo to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South America

What is the cheapest month to book a flight from Buffalo to South America?

Currently, December is the cheapest month in which you can book a flight from Buffalo to South America (average of $152). Flying from Buffalo to South America in October is currently the most expensive (average of $521). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SA?

Find hourly flight availability from Buffalo to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 12, 2025.

It’s typically best to fly out from Buffalo to South America in the afternoon. Doing so could potentially save you 33% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated diciembre 12, 2025.
Get a feel of what it's like to fly with Delta and LATAM Airlines from Buffalo to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
LATAM Airlines
7.5
Good
1,889 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to South America?

    Buffalo (BUF) is the airport you will fly out of if you book a flight from Buffalo to South America. It is only a 8.3 mi journey to Buffalo (BUF) from Buffalo’s city center.

  • How long is the flight from Buffalo to South America?

    Departing from Buffalo to South America will take you 8h 50m. Buffalo and South America are separated by a distance of 2252 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Buffalo to South America one-way?

    The cheapest airline one-way is JetBlue, with whom users have recently found tickets for as low as $241. However, be on the lookout for offers from Avianca and LATAM Airlines, as they are both options that can get you from Buffalo to South America for a low price.

  • What are the most popular routes from Buffalo to South America?

    While some choose either Buffalo - Buenos Aires Ministro Pistarini or Buffalo - Bogotá El Dorado, Buffalo - Medellín Jose Maria Cordova Intl is the most popular route from Buffalo to South America.

  • Can I find deals for flights from Buffalo to South America that include hotel bookings?

    Yes. In addition to deals on Buffalo to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South America.

  • Can I find deals for business class flights from Buffalo to South America?

    Yes. Cheapflights offers flight deals from Buffalo to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to South America?

    Currently, December is the cheapest month in which you can book a flight from Buffalo to South America (average of $152). Flying from Buffalo to South America in October is currently the most expensive (average of $521). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to South America

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Top 2 airlines flying from Buffalo to South America

Discover the top 2 airlines that operate flights from Buffalo to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$467Average$684FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$494Average$769FlexibilityNo cancel feeOn-time81%

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