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South America

$158+ Cheap flights from Buffalo (BUF) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — BOG
Apr 10 — Apr 171
Fri 4/10
Fri 4/17
1 adult, Economy
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Cheap flight deals from Buffalo to South America

Cheapest flights from Buffalo to South America
Explore the most affordable flight options available from Buffalo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.

This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:00 am
BUF
-
MDE
2 stops15h 10m
United Airlines
Wed 4/299:45 am
MDE
-
BUF
2 stops13h 07m
United Airlines
Deal found 3/8$372
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:28 pm
BUF
-
MDE
2 stops18h 20m
American Airlines
Fri 5/11:50 pm
MDE
-
BUF
2 stops22h 15m
American Airlines
Deal found 3/10$392
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:24 am
BUF
-
CTG
2 stops9h 51m
American Airlines
Thu 3/261:28 pm
CTG
-
BUF
2 stops22h 23m
American Airlines
Deal found 3/7$420
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:09 am
BUF
-
MDE
2 stops16h 01m
United Airlines
Sat 5/29:45 am
MDE
-
BUF
2 stops22h 54m
United Airlines
Deal found 3/9$437
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am
BUF
-
MDE
2 stops16h 10m
United Airlines
Wed 10/149:45 am
MDE
-
BUF
2 stops23h 04m
United Airlines
Deal found 3/6$466
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:43 pm
BUF
-
CTG
2 stops23h 22m
American Airlines
Mon 9/282:05 pm
CTG
-
BUF
2 stops21h 10m
American Airlines
Deal found 3/9$474
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:19 am
BUF
-
MDE
2 stops17h 20m
American Airlines
Wed 4/86:00 am
MDE
-
BUF
2 stops14h 36m
American Airlines
Deal found 3/10$477
This Orbitz deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:00 am
BUF
-
MDE
1 stop9h 02m
JetBlue
Sat 5/21:20 pm
MDE
-
BUF
2 stops24h 39m
JetBlue
Deal found 3/9$479
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:09 am
BUF
-
MDE
2 stops16h 01m
United Airlines
Sun 4/269:45 am
MDE
-
BUF
2 stops33h 58m
United Airlines
Deal found 3/10$486
This Expedia deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am
BUF
-
CTG
1 stop9h 00m
JetBlue
Mon 9/282:30 pm
CTG
-
BUF
2 stops17h 23m
JetBlue
Deal found 3/9$497
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:39 pm
BUF
-
CTG
2 stops20h 36m
American Airlines
Thu 3/263:15 pm
CTG
-
BUF
2 stops20h 36m
American Airlines
Deal found 3/6$503
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:30 pm
BUF
-
MDE
2 stops26h 35m
United Airlines
Thu 11/1210:45 am
MDE
-
BUF
2 stops23h 04m
United Airlines
Deal found 3/8$511

Find flight deals from Buffalo to South America

Keep the following information in mind while searching for Buffalo to South America flight deals. Data was last updated March 11, 2026.

Round-trip from

$372
(United Airlines)

One-way from

$158
(United Airlines)

Popular in

June

Cheapest in

December

Average price

$377
From Buffalo to South America
Search Deals
One-way flight from Buffalo to South America
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($160 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Buffalo to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Wed 4/22

7:00 am-9:10 pm

2 stops15h 10m

Medellín Jose Maria Cordova Intl

Wed 4/29

9:45 am-11:52 pm

2 stops13h 07m

$372

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Mon 4/27

6:09 am-9:10 pm

2 stops16h 01m

Medellín Jose Maria Cordova Intl

Sat 5/2

9:45 am-9:39 am

2 stops22h 54m

$437

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Mon 4/27

6:00 am-2:02 pm

1 stop9h 02m

Medellín Jose Maria Cordova Intl

Sat 5/2

1:20 pm-2:59 pm

2 stops24h 39m

$479

BuffaloMedellín

BUF - MDE

BUFMDE

Buffalo

Sun 4/12

6:09 am-9:10 pm

2 stops16h 01m

Medellín Jose Maria Cordova Intl

Sun 4/26

9:45 am-8:43 pm

2 stops33h 58m

$486

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Tue 4/21

6:00 am-6:15 pm

1 stop13h 15m

Bogotá El Dorado

Tue 4/28

7:10 am-9:17 pm

1 stop13h 07m

$515

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Thu 5/7

6:15 am-1:40 pm

1 stop8h 25m

Bogotá El Dorado

Mon 6/1

11:00 am-11:59 pm

2 stops11h 59m

$530

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Wed 5/6

6:00 am-7:15 pm

2 stops14h 15m

Bogotá El Dorado

Mon 6/1

11:00 am-9:03 am

2 stops21h 03m

$530

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Wed 5/6

6:05 am-7:15 pm

2 stops14h 10m

Bogotá El Dorado

Sun 5/31

2:55 pm-8:20 am

2 stops16h 25m

$540

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Wed 5/6

7:00 am-6:45 pm

2 stops12h 45m

Bogotá El Dorado

Sun 5/31

8:40 am-7:35 pm

1 stop9h 55m

$540

BuffaloBogotá

BUF - BOG

BUFBOG

Buffalo

Sat 5/2

11:02 am-4:54 am

2 stops18h 52m

Bogotá El Dorado

Tue 5/5

12:14 am-4:54 pm

2 stops15h 40m

$550

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/6

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
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6

Best time to book a flight from Buffalo to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South America

What is the cheapest month to book a flight from Buffalo to South America?

Currently, December is the cheapest month in which you can book a flight from Buffalo to South America (average of $152). Flying from Buffalo to South America in November is currently the most expensive (average of $534). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated March 11, 2026.
Get a feel of what it's like to fly with Delta and LATAM Airlines from Buffalo to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,278 reviews

Comfort

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,278 reviews
Delta
7.9
Good
8,278 reviews

Comfort

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
LATAM Airlines
7.4
Good
1,916 reviews
Delta
7.9
Good
8,278 reviews

Comfort

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to South America?

    Buffalo (BUF) is the airport you will fly out of if you book a flight from Buffalo to South America. It is only a 8.3 mi journey to Buffalo (BUF) from Buffalo’s city center.

  • How long is the flight from Buffalo to South America?

    Departing from Buffalo to South America will take you 8h 25m. Buffalo and South America are separated by a distance of 2655 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Buffalo to South America one-way?

    The cheapest airline one-way is JetBlue, with whom users have recently found tickets for as low as $143. However, be on the lookout for offers from Avianca and LATAM Airlines, as they are both options that can get you from Buffalo to South America for a low price.

  • What are the most popular routes from Buffalo to South America?

    While some choose either Buffalo - Cartagena Rafael Nunez or Buffalo - Lima J Chavez Intl, Buffalo - Sao Paulo Guarulhos Intl is the most popular route from Buffalo to South America.

  • Can I find deals for flights from Buffalo to South America that include hotel bookings?

    Yes. In addition to deals on Buffalo to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South America.

  • Can I find deals for business class flights from Buffalo to South America?

    Yes. Cheapflights offers flight deals from Buffalo to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to South America?

    Currently, December is the cheapest month in which you can book a flight from Buffalo to South America (average of $152). Flying from Buffalo to South America in November is currently the most expensive (average of $534). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Buffalo to South America

Discover the top 2 airlines that operate flights from Buffalo to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$320Average$702FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$587Average$779FlexibilityNo cancel feeOn-time81%

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