Santa Cruz de la Sierra

$202+ Cheap flights from the United States to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — VVI
Jan 17 — Jan 241
We work with more than 300 partners to bring you better travel deals

Find cheap flights from USA to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from USA to Santa Cruz de la Sierra

Cheapest flights from USA to Santa Cruz de la Sierra
Explore the most affordable flight options available from USA to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Copa Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:47 pmMIA - VVI
1 stop8h 59mCopa Airlines
Thu 1/111:44 amVVI - MIA
1 stop10h 40mCopa Airlines
Deal found 12/17$505
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2712:47 pmMIA - VVI
1 stop8h 59mCopa Airlines
Thu 1/111:44 amVVI - MIA
1 stop13h 53mCopa Airlines
Deal found 12/16$543
This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:20 pmJFK - VVI
1 stop11h 15mAvianca
Tue 1/273:40 amVVI - JFK
1 stop20h 05mAvianca
Deal found 12/17$568
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:45 amMIA - VVI
2 stops37h 01mUnited Airlines
Thu 1/811:44 amVVI - MIA
2 stops35h 31mUnited Airlines
Deal found 12/16$573
This Copa Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:27 pmMIA - VVI
1 stop9h 09mCopa Airlines
Thu 1/111:44 amVVI - MIA
1 stop13h 53mCopa Airlines
Deal found 12/16$589
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:00 amMCO - VVI
2 stops17h 36mUnited Airlines
Mon 12/2911:40 amVVI - MCO
2 stops22h 08mUnited Airlines
Deal found 12/17$597
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:28 pmDCA - VVI
2 stops53h 22mUnited Airlines
Sat 3/2811:42 amVVI - DCA
2 stops50h 07mUnited Airlines
Deal found 12/16$600
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:50 amMCO - VVI
2 stops14h 46mUnited Airlines
Tue 12/3011:40 amVVI - MCO
2 stops31h 14mUnited Airlines
Deal found 12/16$605
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:56 amMIA - VVI
2 stops38h 40mUnited Airlines
Sat 1/3111:44 amVVI - MIA
2 stops35h 10mUnited Airlines
Deal found 12/16$613
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:56 amMIA - VVI
2 stops38h 40mUnited Airlines
Tue 1/2711:44 amVVI - MIA
3 stops35h 10mUnited Airlines
Deal found 12/16$628
This Copa Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:20 amMIA - VVI
1 stop10h 26mCopa Airlines
Wed 1/141:15 amVVI - MIA
1 stop11h 17mCopa Airlines
Deal found 12/17$637
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2812:47 pmMIA - VVI
1 stop8h 59mCopa Airlines
Wed 12/311:15 amVVI - MIA
1 stop11h 02mCopa Airlines
Deal found 12/17$642

Find flight deals from USA to Santa Cruz de la Sierra

Keep the following information in mind while searching for USA to Santa Cruz de la Sierra flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$451
(Gotogate)

One-way from

$202
(Cheapflightsfares)

Popular in

December

Cheapest in

October

Average price

$1,250
Provider with most accurate pricing for New York (NYC)-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Provider most trusted by Cheapflights users for New York (NYC)-Santa Cruz de la Sierra Viru Viru Intl flights.
From USA to Santa Cruz de la Sierra Viru Viru Intl
One-way flight from USA to Santa Cruz de la Sierra Viru Viru Intl
Highest demand for flights based on searches. 11% potential increase in price ($108 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($42 potential savings vs. average RT price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from USA to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from the United States to Santa Cruz de la Sierra that are best for you.

Fly from

USA

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

New YorkSanta Cruz de la Sierra

JFK - VVI

JFKVVI

New York John F Kennedy Intl

Mon 2/23

5:50 am-2:35 am

2 stops19h 45m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/2

3:40 am-10:45 pm

1 stop20h 05m

$452

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Thu 3/12

12:20 pm-10:50 pm

1 stop10h 30m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/23

11:42 am-1:40 am

1 stop13h 58m

$460

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Fri 2/20

7:00 am-2:35 am

1 stop18h 35m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/3

3:40 am-9:15 pm

2 stops18h 35m

$487

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Mon 3/2

5:26 am-10:50 pm

1 stop16h 24m

Santa Cruz de la Sierra Viru Viru Intl

Sat 4/4

1:15 am-12:18 pm

1 stop11h 03m

$514

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Sun 1/25

5:01 am-10:50 pm

1 stop16h 49m

Santa Cruz de la Sierra Viru Viru Intl

Thu 2/19

1:15 am-6:56 pm

1 stop18h 41m

$534

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Sun 2/1

1:50 pm-2:35 am

2 stops32h 45m

Santa Cruz de la Sierra Viru Viru Intl

Fri 2/20

3:40 am-10:55 am

3 stops35h 15m

$534

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Thu 1/22

5:01 am-10:50 pm

1 stop16h 49m

Santa Cruz de la Sierra Viru Viru Intl

Sat 2/21

1:15 am-6:56 pm

1 stop18h 41m

$534

New YorkSanta Cruz de la Sierra

JFK - VVI

JFKVVI

New York John F Kennedy Intl

Wed 2/4

6:30 am-2:35 am

1 stop19h 05m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/17

3:40 am-11:45 pm

1 stop20h 05m

$539

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Thu 3/12

6:01 am-10:50 pm

1 stop16h 49m

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/21

1:14 am-12:07 pm

1 stop10h 53m

$539

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Sat 2/14

5:01 am-10:50 pm

1 stop16h 49m

Santa Cruz de la Sierra Viru Viru Intl

Wed 2/25

1:15 am-6:56 pm

1 stop18h 41m

$539

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from USA to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from USA with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the United States to Santa Cruz de la Sierra

What is the cheapest month to book a flight from USA to Santa Cruz de la Sierra?

Currently, February is the cheapest month in which you can book a flight from USA to Santa Cruz de la Sierra (average of $61). Flying from USA to Santa Cruz de la Sierra in October is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from US to VVI?

Find hourly flight availability from USA to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s optimal to fly from USA to Santa Cruz de la Sierra in the morning. By choosing this option you can save up to 19% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from USA to Santa Cruz de la Sierra?

Use this chart to determine the cheapest time to fly round-trip from USA to Santa Cruz de la Sierra. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their USA to Santa Cruz de la Sierra flight should consider departing on Saturday mornings when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How often are flights from the United States to Santa Cruz de la Sierra delayed?

About 20% of weekly flights between United States and Santa Cruz de la Sierra have experienced delays in the past year, with the average delay time being 154 minutes.

What is the most punctual flight time for the United States to Santa Cruz de la Sierra flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Saturday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on the United States to Santa Cruz de la Sierra flights?

Over the last year, BoA have had the lowest number of delays on this route, with just 11% of flights being delayed.

The best insider tips for theUnited States to Santa Cruz de la Sierra flights

AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your theUnited States to Santa Cruz de la Sierra trip
Airlines
Copa Airlines

Copa's Dreams Business Class offers lie-flat seats on Boeing Max aircraft for enhanced comfort.


Copa offers a Panama Stopover program for up to 7 days at no extra cost.

Avianca

Avianca's Business Class offers lie-flat seats and luxury amenity kits on long-haul flights.


Avianca's Classic fare includes a checked bag and seat selection, ideal for international flights.

United Airlines

United's Polaris Business Class offers lie-flat seats and Saks Fifth Avenue bedding on long-haul flights.


United's Premium Plus offers extra legroom, upgraded meals, and two checked bags on international routes.

LATAM Airlines

LATAM's Premium Business offers lie-flat seats and two checked bags on international flights.


LATAM's LATAM+ seats offer more legroom and earlier boarding on international flights.

Our travel experts
Paul Rubio

Paul Rubio

Expert on Copa Airlines and LATAM Airlines

Paul Rubio

Paul Rubio

Travel journalist and photographer Paul Rubio is a Miami native (and current resident), who has lived in nine countries and traveled to 137. He is an expert in luxury travel, eco-travel, loyalty programs, hotels, airports and airlines. He is a contributing editor at AFAR, Condé Nast Traveler, LUXURY Magazine, and Palm Beach Illustrated.

Read more
Matt Meltzer

Matt Meltzer

Expert on Avianca

Matt Meltzer

Matt Meltzer

Matt Meltzer has been a travel writer for over a decade, covering U.S. domestic locations and hotels for Thrillist, Fifty Grande, Matador Network, Conde Nast Traveler, and other top publications. He's won multiple travel journalism awards from the Society of American Travel Writers and North American Travel Journalists Association, and currently resides in South Florida.

Read more
Harriet Baskas

Harriet Baskas

Expert on United Airlines

Harriet Baskas

Harriet Baskas

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Read more

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated December 18, 2025.
See what other customers who have flown with Copa Airlines, LATAM Airlines, and United Airlines from the United States to Santa Cruz de la Sierra have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.6

Crew

8.1

Comfort

7.4

Entertainment

6.8

Food

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Overall

7.6

Crew

8.1

Comfort

7.4

Entertainment

6.8

Food

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Overall

7.6

Crew

8.1

Comfort

7.4

Entertainment

6.8

Food

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Overall

7.6

Crew

8.1

Comfort

7.4

Entertainment

6.8

Food

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Overall

7.6

Crew

8.1

Comfort

7.4

Entertainment

6.8

Food

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Overall

7.6

Crew

8.1

Comfort

7.4

Entertainment

6.8

Food

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from USA to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Santa Cruz de la Sierra from United States?

    For a flight from United States to Santa Cruz de la Sierra, you will be flying into Viru Viru Intl. Santa Cruz de la Sierra Viru Viru Intl (VVI) is just 11.5 mi from the center of the city.

  • How long is the flight from USA to Santa Cruz de la Sierra?

    Avianca, Copa Airlines, and United Airlines can get you from USA to Santa Cruz de la Sierra in just under 10h 30m. Your travel time can differ by up to 26h 20m. USA and Santa Cruz de la Sierra are separated by a distance of 3213 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from USA to Santa Cruz de la Sierra one-way?

    The cheapest airlines for a one-way flight from USA to Santa Cruz de la Sierra are Avianca ($165), Copa Airlines ($195), and United Airlines ($221).

  • What are the most popular routes from USA to Santa Cruz de la Sierra?

  • Can I find deals for flights from USA to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on USA to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from USA to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from USA to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from USA to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from USA to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from USA to Santa Cruz de la Sierra?

    Currently, February is the cheapest month in which you can book a flight from USA to Santa Cruz de la Sierra (average of $61). Flying from USA to Santa Cruz de la Sierra in October is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for USA to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from USA to Santa Cruz de la Sierra

Discover the top 5 airlines that operate flights from USA to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$296Average$749FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$380Average$740FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$453Average$941FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$479Average$1,074FlexibilityNo cancel feeOn-time81%
BoACheapest$522Average$692FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.