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Santa Cruz de la Sierra

$194+ Cheap flights from the United States to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — VVI
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from USA to Santa Cruz de la Sierra

Keep the following information in mind while searching for USA to Santa Cruz de la Sierra flight deals. Data was last updated July 31, 2025.

Round-trip from

$440
(Cheapflightsfares)

One-way from

$194
(Mytrip)

Popular in

December

Cheapest in

October

Average price

$850
From USA to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from USA to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($174 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($76 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from USA to Santa Cruz de la Sierra

Cheapest flights from USA to Santa Cruz de la Sierra
Explore the most affordable flight options available from USA to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/17:45 amJFK - VVI
1 stop18h 05mAvianca
Sun 9/142:50 amVVI - JFK
1 stop11h 09mAvianca
Deal found 7/31$440
This Cheapflightsfares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/224:05 amIAD - VVI
2 stops21h 45mAvianca
Sun 10/192:50 amVVI - IAD
2 stops25h 30mAvianca
Deal found 7/29$484
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/224:34 pmIAD - VVI
1 stop11h 02mCopa Airlines
Mon 10/2011:59 amVVI - IAD
1 stop16h 21mCopa Airlines
Deal found 7/31$489
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:09 amMIA - VVI
1 stop16h 16mCopa Airlines
Sat 10/41:09 amVVI - MIA
1 stop13h 26mCopa Airlines
Deal found 7/31$490
This Priceline deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/174:35 pmMIA - VVI
1 stop9h 00mAvianca
Thu 11/273:40 amVVI - MIA
1 stop19h 50mAvianca
Deal found 7/31$495
This FlightHub deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/228:12 amMIA - VVI
2 stops20h 23mLATAM Airlines
Wed 10/295:25 amVVI - MIA
2 stops25h 07mLATAM Airlines
Deal found 7/30$526
This Gotogate deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/43:32 pmJFK - VVI
1 stop30h 53mCopa Airlines
Wed 9/1712:15 pmVVI - JFK
1 stop12h 31mCopa Airlines
Deal found 7/31$535
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/58:41 amBOS - VVI
1 stop18h 55mCopa Airlines
Fri 10/171:09 amVVI - BOS
1 stop21h 44mCopa Airlines
Deal found 7/31$563
This Tripair deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Tripair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/49:35 amEWR - VVI
1 stop12h 50mUnited Airlines
Tue 9/161:09 amVVI - EWR
1 stop14h 55mUnited Airlines
Deal found 7/31$563
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/49:55 amLGA - VVI
2 stops36h 30mUnited Airlines
Tue 9/161:09 amVVI - LGA
2 stops22h 15mUnited Airlines
Deal found 7/31$571
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/226:00 amBWI - VVI
2 stops40h 25mUnited Airlines
Tue 10/71:09 amVVI - BWI
2 stops21h 49mUnited Airlines
Deal found 7/29$572
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/66:31 pmMIA - VVI
1 stop27h 48mMultiple Airlines
Fri 8/82:50 amVVI - MIA
1 stop9h 40mMultiple Airlines
Deal found 7/30$575

Cheapflights Fare Finder

 
Customize your flight search to find flights from USA to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from the United States to Santa Cruz de la Sierra that are best for you.

Fly from

USA

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

New YorkSanta Cruz de la Sierra

JFK - VVI

JFKVVI

New York John F Kennedy Intl

Mon 9/1

7:45 am-1:50 am

1 stop18h 05m

Santa Cruz de la Sierra Viru Viru Intl

Sun 9/14

2:50 am-10:40 pm

1 stop19h 50m

$440

Washington, D.C.Santa Cruz de la Sierra

IAD - VVI

IADVVI

Washington, D.C. Dulles Intl

Mon 9/22

4:05 am-1:50 am

2 stops21h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sun 10/19

2:50 am-4:20 am

2 stops25h 30m

$484

Washington, D.C.Santa Cruz de la Sierra

IAD - VVI

IADVVI

Washington, D.C. Dulles Intl

Mon 9/22

4:34 pm-3:36 am

1 stop11h 02m

Santa Cruz de la Sierra Viru Viru Intl

Mon 10/20

11:59 am-4:20 am

1 stop16h 21m

$489

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Thu 9/25

6:09 am-10:25 pm

1 stop16h 16m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/4

1:09 am-2:35 pm

1 stop13h 26m

$490

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Mon 11/17

4:35 pm-2:35 am

1 stop9h 00m

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/27

3:40 am-10:30 pm

1 stop19h 50m

$495

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Wed 10/22

8:12 am-4:35 am

2 stops20h 23m

Santa Cruz de la Sierra Viru Viru Intl

Wed 10/29

5:25 am-6:32 am

2 stops25h 07m

$526

New YorkSanta Cruz de la Sierra

JFK - VVI

JFKVVI

New York John F Kennedy Intl

Thu 9/4

3:32 pm-10:25 pm

1 stop30h 53m

Santa Cruz de la Sierra Viru Viru Intl

Wed 9/17

12:15 pm-12:46 am

1 stop12h 31m

$535

NewarkSanta Cruz de la Sierra

EWR - VVI

EWRVVI

Newark

Thu 9/4

9:35 am-10:25 pm

1 stop12h 50m

Santa Cruz de la Sierra Viru Viru Intl

Tue 9/16

1:09 am-4:04 pm

1 stop14h 55m

$563

BostonSanta Cruz de la Sierra

BOS - VVI

BOSVVI

Boston Logan Intl

Sun 10/5

8:41 am-3:36 am

1 stop18h 55m

Santa Cruz de la Sierra Viru Viru Intl

Fri 10/17

1:09 am-10:53 pm

1 stop21h 44m

$563

New YorkSanta Cruz de la Sierra

LGA - VVI

LGAVVI

New York LaGuardia

Thu 9/4

9:55 am-10:25 pm

2 stops36h 30m

Santa Cruz de la Sierra Viru Viru Intl

Tue 9/16

1:09 am-11:24 pm

2 stops22h 15m

$571

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 60 results
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The best insider tips for theUnited States to Santa Cruz de la Sierra flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your theUnited States to Santa Cruz de la Sierra trip
Airlines
Copa Airlines

Copa's Dreams Business Class offers lie-flat seats on Boeing Max aircraft for enhanced comfort.


Copa offers a Panama Stopover program for up to 7 days at no extra cost.

Read more about Copa Airlinesby Paul Rubio
Avianca

Avianca's Business Class offers lie-flat seats and luxury amenity kits on long-haul flights.


Avianca's Classic fare includes a checked bag and seat selection, ideal for international flights.

Read more about Aviancaby Matt Meltzer
United Airlines

United's Polaris Business Class offers lie-flat seats and Saks Fifth Avenue bedding on long-haul flights.


United's Premium Plus offers extra legroom, upgraded meals, and two checked bags on international routes.

Read more about United Airlinesby Harriet Baskas
LATAM Airlines

LATAM's Premium Business offers lie-flat seats and two checked bags on international flights.


LATAM's LATAM+ seats offer more legroom and earlier boarding on international flights.

Read more about LATAM Airlinesby Paul Rubio
Our travel experts
Paul Rubio

Paul Rubio

Expert on Copa Airlines and LATAM Airlines

Paul Rubio

Paul Rubio

Travel journalist and photographer Paul Rubio is a Miami native (and current resident), who has lived in nine countries and traveled to 137. He is an expert in luxury travel, eco-travel, loyalty programs, hotels, airports and airlines. He is a contributing editor at AFAR, Condé Nast Traveler, LUXURY Magazine, and Palm Beach Illustrated.

Read more
Matt Meltzer

Matt Meltzer

Expert on Avianca

Matt Meltzer

Matt Meltzer

Matt Meltzer has been a travel writer for over a decade, covering U.S. domestic locations and hotels for Thrillist, Fifty Grande, Matador Network, Conde Nast Traveler, and other top publications. He's won multiple travel journalism awards from the Society of American Travel Writers and North American Travel Journalists Association, and currently resides in South Florida.

Read more
Harriet Baskas

Harriet Baskas

Expert on United Airlines

Harriet Baskas

Harriet Baskas

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Read more

Best time to book a flight from USA to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from USA with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the United States to Santa Cruz de la Sierra

What is the cheapest month to book a flight from USA to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from USA to Santa Cruz de la Sierra (average of $597). Flying from USA to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from US to VVI?

Find hourly flight availability from USA to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from USA to Santa Cruz de la Sierra as you normally would.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated July 31, 2025.
See what other customers who have flown with LATAM Airlines, Copa Airlines, and United Airlines from the United States to Santa Cruz de la Sierra have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,822 reviews

Comfort

7.4

Crew

8.1

Entertainment

7.0

Boarding

7.6

Food

6.7

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
LATAM Airlines
7.5
Good
1,822 reviews
LATAM Airlines
7.5
Good
1,822 reviews

Comfort

7.4

Crew

8.1

Entertainment

7.0

Boarding

7.6

Food

6.7

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
Copa Airlines
7.5
Good
1,493 reviews
LATAM Airlines
7.5
Good
1,822 reviews

Comfort

7.4

Crew

8.1

Entertainment

7.0

Boarding

7.6

Food

6.7

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
United Airlines
7.4
Good
8,902 reviews
LATAM Airlines
7.5
Good
1,822 reviews

Comfort

7.4

Crew

8.1

Entertainment

7.0

Boarding

7.6

Food

6.7

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
GOL
7.3
Good
1,090 reviews
LATAM Airlines
7.5
Good
1,822 reviews

Comfort

7.4

Crew

8.1

Entertainment

7.0

Boarding

7.6

Food

6.7

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
BoA
6.8
Okay
136 reviews
LATAM Airlines
7.5
Good
1,822 reviews

Comfort

7.4

Crew

8.1

Entertainment

7.0

Boarding

7.6

Food

6.7

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing

Related info for your journey

Find useful and relevant information for your journey from USA to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from United States?

    For a flight from United States to Santa Cruz de la Sierra, you will be flying into Viru Viru Intl. Santa Cruz de la Sierra Viru Viru Intl (VVI) is just 11.5 mi from the center of the city.

  • What are the cheapest airlines to fly from USA to Santa Cruz de la Sierra one-way?

    The cheapest airlines for a one-way flight from USA to Santa Cruz de la Sierra are Avianca ($194), United Airlines ($247), and Copa Airlines ($258).

  • What are the most popular routes from USA to Santa Cruz de la Sierra?

    Most travelers choose Miami - Santa Cruz de la Sierra Viru Viru Intl, Washington, D.C. Dulles Intl - Santa Cruz de la Sierra Viru Viru Intl or Washington, D.C. Reagan-National - Santa Cruz de la Sierra Viru Viru Intl when deciding on the best route from USA to Santa Cruz de la Sierra.

  • Can I find deals for flights from USA to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on USA to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from USA to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from USA to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from USA to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from USA to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from USA to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from USA to Santa Cruz de la Sierra (average of $597). Flying from USA to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for USA to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Santa Cruz de la Sierra flights
Dulles Intl to Santa Cruz de la Sierra flights
Dulles Intl to La Paz flights
Reagan-National to Santa Cruz de la Sierra flights
John F Kennedy Intl to La Paz flights
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John F Kennedy Intl to Santa Cruz de la Sierra flights
Reagan-National to La Paz flights
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San Francisco to Santa Cruz de la Sierra flights
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George Bush Intcntl to Santa Cruz de la Sierra flights
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O'Hare Intl to Santa Cruz de la Sierra flights
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Love Field to La Paz flights
Orlando to Santa Cruz de la Sierra flights
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O'Hare Intl to La Paz flights
St. Louis to Santa Cruz de la Sierra flights
Dallas/Fort Worth to La Paz flights
Atlanta to La Paz flights
Raleigh to Santa Cruz de la Sierra flights
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Sky Harbor Intl to La Paz flights
San Diego to La Paz flights
Minneapolis to La Paz flights

Top 5 airlines flying from USA to Santa Cruz de la Sierra

Discover the top 5 airlines that operate flights from USA to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$376Average$792FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$379Average$742FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$453Average$842FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$479Average$1,144FlexibilityNo cancel feeOn-time81%
BoACheapest$532Average$690FlexibilityNo cancel feeOn-timeN/A

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