$428+ Cheap flights from Tampa (TPA) to Santa Cruz de la Sierra (VVI)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — VVI
Nov 10 — Nov 171
Round-trip
1 adult, Economy
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Find cheap flights from Tampa to Santa Cruz de la Sierra with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Tampa to Santa Cruz de la Sierra
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Best
Last-minute
One-way
Cheapest flights from Tampa to Santa Cruz de la SierraExplore the most affordable flight options available from Tampa to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 11, 2026.
Explore the most affordable flight options available from Tampa to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 11, 2026.
This United deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:10 am -
2 stops17h 32m
Sat 12/191:10 am -
2 stops20h 32m
Deal found 10/7![Multiple Airlines logo]()
$721
This United deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:00 am -
2 stops15h 44m
Thu 10/221:12 am -
2 stops22h 20m
Deal found 10/6![Multiple Airlines logo]()
$730
This United deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:13 pm -
2 stops51h 31m
Thu 10/153:35 am -
2 stops31h 56m
Deal found 10/9![Multiple Airlines logo]()
$803
This United deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:00 am -
2 stops19h 37m
Thu 11/123:45 am -
2 stops15h 17m
Deal found 10/9![Multiple Airlines logo]()
$863
This Copa Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:27 pm -
1 stop12h 11m
Sat 10/241:12 am -
1 stop12h 27m
Deal found 10/6![Copa Airlines logo]()
$866
This Trip.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:27 pm -
1 stop12h 11m
Thu 10/221:12 am -
1 stop12h 23m
Deal found 10/9![Copa Airlines logo]()
$873
This lol.travel deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:16 pm -
1 stop9h 21m
Thu 11/121:08 am -
1 stop21h 58m
Deal found 10/9![Copa Airlines logo]()
$878
This Gotogate deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:27 pm -
1 stop12h 11m
Thu 10/151:12 am -
1 stop12h 23m
Deal found 10/9![Copa Airlines logo]()
$892
This Copa Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:14 pm -
1 stop9h 28m
Sat 12/191:10 am -
1 stop12h 27m
Deal found 10/10![Copa Airlines logo]()
$1,012
Best flights from Tampa to Santa Cruz de la SierraDiscover carefully curated flight deals from Tampa to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 11, 2026.
Discover carefully curated flight deals from Tampa to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 11, 2026.
This United deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:00 am -
2 stops19h 37m
Thu 11/123:45 am -
2 stops15h 17m
Deal found 10/9![Multiple Airlines logo]()
$863
This Copa Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:51 am -
1 stop16h 57m
Sat 12/191:10 am -
1 stop21h 50m
Deal found 10/7![Copa Airlines logo]()
$1,190
This Avianca deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:50 pm -
1 stop10h 50m
Mon 11/23:45 am -
1 stop10h 40m
Deal found 10/6![Avianca logo]()
$1,389
This Mytrip deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/62:50 pm -
3 stops24h 00m
Sun 12/205:30 am -
2 stops32h 55m
Deal found 10/7![Multiple Airlines logo]()
$1,352
This Copa Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/294:51 am -
1 stop21h 51m
Tue 1/51:14 am -
1 stop21h 46m
Deal found 10/10![Copa Airlines logo]()
$1,385
Last-minute flights from Tampa to Santa Cruz de la SierraDiscover last-minute flight deals from Tampa to Santa Cruz de la Sierra. Data last updated October 11, 2026 and is based on user searches.
Discover last-minute flight deals from Tampa to Santa Cruz de la Sierra. Data last updated October 11, 2026 and is based on user searches.
This United deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:13 pm -
2 stops51h 31m
Thu 10/153:35 am -
2 stops31h 56m
Deal found 10/9![Multiple Airlines logo]()
$803
This Gotogate deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:27 pm -
1 stop12h 11m
Thu 10/151:12 am -
1 stop12h 23m
Deal found 10/9![Copa Airlines logo]()
$892
This United deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:00 am -
2 stops15h 44m
Thu 10/221:12 am -
2 stops22h 20m
Deal found 10/6![Multiple Airlines logo]()
$730
This Copa Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:27 pm -
1 stop12h 11m
Sat 10/241:12 am -
1 stop12h 27m
Deal found 10/6![Copa Airlines logo]()
$866
This Trip.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:27 pm -
1 stop12h 11m
Thu 10/221:12 am -
1 stop12h 23m
Deal found 10/9![Copa Airlines logo]()
$873
This United deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:00 am -
2 stops19h 37m
Thu 11/123:45 am -
2 stops15h 17m
Deal found 10/9![Multiple Airlines logo]()
$863
This lol.travel deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:16 pm -
1 stop9h 21m
Thu 11/121:08 am -
1 stop21h 58m
Deal found 10/9![Copa Airlines logo]()
$878
One-way flights from Tampa to Santa Cruz de la SierraSearch for one-way flight options from Tampa to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated October 11, 2026.
Search for one-way flight options from Tampa to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated October 11, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:51 am -
1 stop16h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Copa Airlines logo]()
$428
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:00 am -
2 stops38h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![United Airlines logo]()
$475
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:00 am -
2 stops39h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![United Airlines logo]()
$499
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:57 pm -
3 stops52h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Multiple Airlines logo]()
$535
This FlightHub deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:45 pm -
1 stop10h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Avianca logo]()
$969
Find flight deals from Tampa to Santa Cruz de la Sierra
Discover tips and strategies to find the most affordable flight options for your journey from Tampa (TPA) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $721 (United) |
One-way from | $428 (Copa Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Tampa to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 11, 2026.
Use the filters below to find and compare flights from Tampa to Santa Cruz de la Sierra that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
TampaSanta Cruz de la Sierra
TPA Tampa - VVI Santa Cruz de la Sierra Viru Viru Intl
TPAVVI
Tampa
Fri 12/4
4:51 am-10:48 pm
1 stop16h 57m
Santa Cruz de la Sierra Viru Viru Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$428
TampaSanta Cruz de la Sierra
TPA Tampa - VVI Santa Cruz de la Sierra Viru Viru Intl
TPAVVI
Tampa
Sat 12/5
10:30 am-10:48 pm
2 stops35h 18m
Santa Cruz de la Sierra Viru Viru Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$475
TampaSanta Cruz de la Sierra
TPA Tampa - VVI Santa Cruz de la Sierra Viru Viru Intl
TPAVVI
Tampa
Fri 10/16
7:00 am-10:44 pm
2 stops39h 44m
Santa Cruz de la Sierra Viru Viru Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$499
TampaSanta Cruz de la Sierra
TPA Tampa - VVI Santa Cruz de la Sierra Viru Viru Intl
TPAVVI
Tampa
Fri 11/6
7:00 am-3:37 am
2 stops19h 37m
Santa Cruz de la Sierra Viru Viru Intl
Thu 11/12
3:45 am-6:02 pm
2 stops15h 17m
$863
TampaSanta Cruz de la Sierra
TPA Tampa - VVI Santa Cruz de la Sierra Viru Viru Intl
TPAVVI
Tampa
Sat 12/5
4:51 am-10:48 pm
1 stop16h 57m
Santa Cruz de la Sierra Viru Viru Intl
Sat 12/19
1:10 am-10:00 pm
1 stop21h 50m
$1,190
TampaSanta Cruz de la Sierra
TPA Tampa - VVI Santa Cruz de la Sierra Viru Viru Intl
TPAVVI
Tampa
Sun 12/6
2:50 pm-3:50 pm
3 stops24h 00m
Santa Cruz de la Sierra Viru Viru Intl
Sun 12/20
5:30 am-1:25 pm
2 stops32h 55m
$1,352
TampaSanta Cruz de la Sierra
TPA Tampa - VVI Santa Cruz de la Sierra Viru Viru Intl
TPAVVI
Tampa
Tue 12/29
4:51 am-3:42 am
1 stop21h 51m
Santa Cruz de la Sierra Viru Viru Intl
Tue 1/5
1:14 am-10:00 pm
1 stop21h 46m
$1,385
TampaSanta Cruz de la Sierra
TPA Tampa - VVI Santa Cruz de la Sierra Viru Viru Intl
TPAVVI
Tampa
Fri 10/30
3:50 pm-2:40 am
1 stop10h 50m
Santa Cruz de la Sierra Viru Viru Intl
Mon 11/2
3:45 am-1:25 pm
1 stop10h 40m
$1,389
Sorted by cheapest first
Compare providers for flights from Tampa to Santa Cruz de la Sierra
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Tampa to Santa Cruz de la Sierra in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Tampa-Santa Cruz de la Sierra flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tampa-Santa Cruz de la Sierra flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tampa-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Tampa-Santa Cruz de la Sierra flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tampa-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Tampa to Santa Cruz de la Sierra
Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Tampa with our price prediction graph.
TPA-VVI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santa Cruz de la Sierra
Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated October 11, 2026.
Get a feel of what it's like to fly with Copa Airlines from Tampa to Santa Cruz de la Sierra by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.6
Food
6.9
Crew
8.1
Boarding
7.8
Entertainment
6.9
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Overall
7.6
Food
6.9
Crew
8.1
Boarding
7.8
Entertainment
6.9
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Tampa to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Santa Cruz de la Sierra by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Tampa to Santa Cruz de la Sierra by cabin class
Find flights from Tampa to Santa Cruz de la Sierra, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Tampa and Santa Cruz de la Sierra flights
Browse other Tampa and Santa Cruz de la Sierra flight options. Last updated on October 11, 2026.
Other flights from Tampa
Browse through other flights departing from Tampa. Flights are based on user searches made on Cheapflights and were last updated on October 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Tampa to Santa Cruz de la Sierra
Discover the top airline that operate flights from Tampa to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$648 | Average$846 | FlexibilityNo cancel fee | On-time70% |