Santa Cruz de la Sierra

$738+ Cheap flights from Denver (DEN) to Santa Cruz de la Sierra (VVI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — VVI
Jun 4 — Jun 111
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Find cheap flights from Denver to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go

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2. Select your favorite providers

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Cheap flight deals from Denver to Santa Cruz de la Sierra

Cheapest flights from Denver to Santa Cruz de la Sierra
Explore the most affordable flight options available from Denver to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.

This Copa Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:43 pm
DEN
-
VVI
1 stop21h 57m
Copa Airlines
Sun 8/301:12 am
VVI
-
DEN
1 stop19h 08m
Copa Airlines
Deal found 5/3$738
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:26 pm
DEN
-
VVI
2 stops32h 14m
United Airlines
Mon 8/2411:47 am
VVI
-
DEN
2 stops22h 53m
United Airlines
Deal found 5/3$753
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:00 am
DEN
-
VVI
2 stops15h 40m
United Airlines
Sat 8/2911:47 am
VVI
-
DEN
3 stops25h 22m
United Airlines
Deal found 5/3$776
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/209:00 pm
DEN
-
VVI
2 stops23h 40m
United Airlines
Mon 8/3111:47 am
VVI
-
DEN
2 stops22h 37m
United Airlines
Deal found 5/3$818
This Copa Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1610:43 pm
DEN
-
VVI
1 stop26h 52m
Copa Airlines
Fri 8/281:12 am
VVI
-
DEN
1 stop19h 08m
Copa Airlines
Deal found 5/3$829
This KAYAK deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:59 pm
DEN
-
VVI
2 stops44h 45m
Copa Airlines
Mon 9/2811:47 am
VVI
-
DEN
2 stops20h 55m
Copa Airlines
Deal found 4/30$875
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:25 pm
DEN
-
VVI
2 stops30h 25m
United Airlines
Tue 11/1711:44 am
VVI
-
DEN
2 stops14h 43m
United Airlines
Deal found 4/30$883
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:40 pm
DEN
-
VVI
2 stops25h 55m
Multiple Airlines
Fri 8/288:35 am
VVI
-
DEN
1 stop26h 02m
Multiple Airlines
Deal found 5/3$946
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:40 pm
DEN
-
VVI
2 stops21h 00m
Multiple Airlines
Fri 8/288:35 am
VVI
-
DEN
1 stop26h 02m
Multiple Airlines
Deal found 5/3$953
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1011:40 pm
DEN
-
VVI
2 stops21h 00m
Multiple Airlines
Fri 8/288:35 am
VVI
-
DEN
1 stop26h 02m
Multiple Airlines
Deal found 5/3$980
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:40 pm
DEN
-
VVI
1 stop26h 10m
Multiple Airlines
Mon 8/2411:35 pm
VVI
-
DEN
2 stops21h 44m
Multiple Airlines
Deal found 5/3$998

Find flight deals from Denver to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 5, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$738
(Copa Airlines)

Popular in

December

Cheapest in

October

Average price

$712
Provider with most accurate pricing for Denver Intl-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Provider most trusted by Cheapflights users for Denver Intl-Santa Cruz de la Sierra Viru Viru Intl flights.
From Denver Intl to Santa Cruz de la Sierra Viru Viru Intl
Highest demand for flights based on searches. 24% potential increase in price ($254 potential increase over avg. RT price).
Cheapest flight prices on average. 7% potential price decrease ($59 potential savings vs. average RT price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Denver to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Thu 8/20

10:43 pm-10:40 pm

1 stop21h 57m

Santa Cruz de la Sierra Viru Viru Intl

Sun 8/30

1:12 am-6:20 pm

1 stop19h 08m

$738

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Fri 5/29

11:59 pm-10:38 pm

2 stops44h 39m

Santa Cruz de la Sierra Viru Viru Intl

Tue 6/23

11:47 am-8:47 am

2 stops23h 00m

$753

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Wed 8/12

11:59 pm-3:35 am

2 stops25h 36m

Santa Cruz de la Sierra Viru Viru Intl

Tue 8/25

11:47 am-12:44 pm

2 stops26h 57m

$753

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Thu 8/20

9:00 pm-10:40 pm

2 stops23h 40m

Santa Cruz de la Sierra Viru Viru Intl

Mon 8/31

11:47 am-8:24 am

2 stops22h 37m

$818

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Sun 8/16

10:43 pm-3:35 am

1 stop26h 52m

Santa Cruz de la Sierra Viru Viru Intl

Fri 8/28

1:12 am-6:20 pm

1 stop19h 08m

$829

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Mon 9/21

10:43 pm-10:44 pm

1 stop22h 01m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/28

11:47 am-8:22 am

2 stops22h 35m

$1,111
Quickest round-trip

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Mon 9/21

10:43 pm-10:44 pm

1 stop22h 01m

Santa Cruz de la Sierra Viru Viru Intl

Sun 9/27

1:12 am-6:11 pm

1 stop18h 59m

$1,148

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Mon 9/21

12:58 pm-2:30 am

3 stops35h 32m

Santa Cruz de la Sierra Viru Viru Intl

Sun 9/27

3:35 am-12:19 pm

2 stops34h 44m

$1,326

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/3

Sorted by cheapest first

Compare providers for flights from Denver to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santa Cruz de la Sierra in May.
ProviderPrice AccuracyTrust Score*
OvagoPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Denver-Santa Cruz de la Sierra flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Denver-Santa Cruz de la Sierra flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Denver-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Denver-Santa Cruz de la Sierra flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santa Cruz de la Sierra

How much does it cost to fly round-trip from Denver to Santa Cruz de la Sierra?

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated May 5, 2026.
Read through reviews of airlines operating flights from Denver to Santa Cruz de la Sierra, such as Copa Airlines and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines

Related info for your journey

Find useful and relevant information for your journey from Denver to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Denver to Santa Cruz de la Sierra?

    Airlines like Copa Airlines and United Airlines fly from Denver to Santa Cruz de la Sierra in about 21h 57m. The time it takes to get you to your destination can typically vary by up to 10h 17m. There are 4786 mi between Denver and Santa Cruz de la Sierra. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Denver to Santa Cruz de la Sierra round-trip?

    Flying on United Airlines is currently your cheapest option to Santa Cruz de la Sierra, with prices starting at $309. Another option worth looking into is Copa Airlines, starting at $606 round trip. United Airlines is priced at 61% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Denver to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Denver to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Denver to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Denver to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Complete your trip

Complete your trip to Santa Cruz de la Sierra by adding a car rental and/or hotel reservation to your travel itinerary.

Top 2 airlines flying from Denver to Santa Cruz de la Sierra

Discover the top 2 airlines that operate flights from Denver to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$309Average$667FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$606Average$795FlexibilityNo cancel feeOn-time70%

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