$277+ Cheap flights from Denver (DEN) to Santa Cruz de la Sierra (VVI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — VVI
Apr 2 — Apr 91
1 adult, Economy
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Find cheap flights from Denver to Santa Cruz de la Sierra with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Denver to Santa Cruz de la Sierra
Cheapest
Best
Last-minute
One-way
Cheapest flights from Denver to Santa Cruz de la SierraExplore the most affordable flight options available from Denver to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 3, 2026.
Explore the most affordable flight options available from Denver to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 3, 2026.
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:00 am
DEN
- VVI
2 stops15h 50m
United Airlines
Tue 4/2111:48 am
VVI
- DEN
2 stops22h 38m
United Airlines
Deal found 2/26![United Airlines logo]()
$653
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:23 pm
DEN
- VVI
2 stops24h 19m
United Airlines
Mon 4/1311:48 am
VVI
- DEN
2 stops33h 52m
United Airlines
Deal found 3/2![United Airlines logo]()
$673
This Copa Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/910:51 pm
DEN
- VVI
1 stop21h 51m
Copa Airlines
Sun 4/121:15 am
VVI
- DEN
1 stop19h 10m
Copa Airlines
Deal found 2/28![Copa Airlines logo]()
$675
This Ovago deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:28 pm
DEN
- VVI
2 stops24h 10m
Multiple Airlines
Mon 7/63:35 am
VVI
- DEN
2 stops22h 22m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$690
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:56 pm
DEN
- VVI
2 stops26h 54m
Multiple Airlines
Mon 4/138:35 am
VVI
- DEN
1 stop27h 05m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$769
This KAYAK deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1811:59 pm
DEN
- VVI
2 stops44h 41m
Multiple Airlines
Thu 7/233:35 am
VVI
- DEN
2 stops22h 22m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$775
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:00 am
DEN
- VVI
3 stops19h 31m
United Airlines
Thu 3/1211:54 am
VVI
- DEN
2 stops23h 00m
United Airlines
Deal found 2/26![United Airlines logo]()
$861
This Copa Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/910:48 pm
DEN
- VVI
1 stop22h 02m
Copa Airlines
Tue 8/41:12 am
VVI
- DEN
1 stop19h 08m
Copa Airlines
Deal found 2/27![Copa Airlines logo]()
$864
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3011:28 am
DEN
- VVI
1 stop15h 22m
Multiple Airlines
Mon 4/203:35 am
VVI
- DEN
2 stops32h 05m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$866
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
DEN
- VVI
2 stops19h 31m
United Airlines
Tue 6/2311:47 am
VVI
- DEN
2 stops22h 35m
United Airlines
Deal found 3/2![United Airlines logo]()
$882
This BusinessClass deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:52 pm
DEN
- VVI
1 stop21h 58m
Copa Airlines
Tue 4/2111:48 am
VVI
- DEN
1 stop32h 37m
Copa Airlines
Deal found 2/26![Copa Airlines logo]()
$889
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:28 am
DEN
- VVI
1 stop15h 22m
Multiple Airlines
Wed 8/511:35 pm
VVI
- DEN
2 stops26h 28m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$921
Best flights from Denver to Santa Cruz de la SierraDiscover carefully curated flight deals from Denver to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 3, 2026.
Discover carefully curated flight deals from Denver to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 3, 2026.
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3011:59 pm
DEN
- VVI
2 stops20h 51m
United Airlines
Tue 4/2111:48 am
VVI
- DEN
3 stops25h 55m
United Airlines
Deal found 2/26![United Airlines logo]()
$653
This Copa Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/910:51 pm
DEN
- VVI
1 stop21h 51m
Copa Airlines
Sun 4/121:15 am
VVI
- DEN
1 stop19h 10m
Copa Airlines
Deal found 2/28![Copa Airlines logo]()
$675
This KAYAK deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1811:59 pm
DEN
- VVI
2 stops44h 41m
Multiple Airlines
Thu 7/233:35 am
VVI
- DEN
2 stops22h 22m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$775
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:38 pm
DEN
- VVI
2 stops30h 02m
United Airlines
Mon 4/1311:48 am
VVI
- DEN
2 stops36h 22m
United Airlines
Deal found 2/27![United Airlines logo]()
$653
This BusinessClass deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:52 pm
DEN
- VVI
1 stop21h 58m
Copa Airlines
Tue 4/2111:48 am
VVI
- DEN
1 stop32h 37m
Copa Airlines
Deal found 2/26![Copa Airlines logo]()
$889
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
DEN
- VVI
2 stops19h 31m
United Airlines
Tue 6/2311:47 am
VVI
- DEN
2 stops22h 35m
United Airlines
Deal found 3/2![United Airlines logo]()
$882
Last-minute flights from Denver to Santa Cruz de la SierraDiscover last-minute flight deals from Denver to Santa Cruz de la Sierra. Data last updated March 3, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Santa Cruz de la Sierra. Data last updated March 3, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:00 am
DEN
- VVI
3 stops19h 31m
United Airlines
Thu 3/1211:54 am
VVI
- DEN
2 stops23h 00m
United Airlines
Deal found 2/26![United Airlines logo]()
$861
This Copa Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/910:48 pm
DEN
- VVI
1 stop22h 02m
Copa Airlines
Tue 8/41:12 am
VVI
- DEN
1 stop19h 08m
Copa Airlines
Deal found 2/27![Copa Airlines logo]()
$864
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:28 am
DEN
- VVI
1 stop15h 22m
Multiple Airlines
Wed 8/511:35 pm
VVI
- DEN
2 stops26h 28m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$921
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3011:59 pm
DEN
- VVI
2 stops20h 51m
United Airlines
Tue 4/2111:48 am
VVI
- DEN
3 stops25h 55m
United Airlines
Deal found 2/26![United Airlines logo]()
$653
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3011:28 am
DEN
- VVI
1 stop15h 22m
Multiple Airlines
Mon 4/203:35 am
VVI
- DEN
2 stops32h 05m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$866
This BusinessClass deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:52 pm
DEN
- VVI
1 stop21h 58m
Copa Airlines
Tue 4/2111:48 am
VVI
- DEN
1 stop32h 37m
Copa Airlines
Deal found 2/26![Copa Airlines logo]()
$889
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:23 pm
DEN
- VVI
2 stops24h 19m
United Airlines
Mon 4/1311:48 am
VVI
- DEN
2 stops33h 52m
United Airlines
Deal found 3/2![United Airlines logo]()
$673
This Copa Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/910:51 pm
DEN
- VVI
1 stop21h 51m
Copa Airlines
Sun 4/121:15 am
VVI
- DEN
1 stop19h 10m
Copa Airlines
Deal found 2/28![Copa Airlines logo]()
$675
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:56 pm
DEN
- VVI
2 stops26h 54m
Multiple Airlines
Mon 4/138:35 am
VVI
- DEN
1 stop27h 05m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$769
One-way flights from Denver to Santa Cruz de la SierraSearch for one-way flight options from Denver to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated March 3, 2026.
Search for one-way flight options from Denver to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated March 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:05 pm
DEN
- VVI
2 stops21h 37m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:49 pm
DEN
- VVI
2 stops20h 53m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:42 pm
DEN
- VVI
2 stops31h 58m
United Airlines
Deal found 2/27![United Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:05 pm
DEN
- VVI
1 stop27h 45m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:09 pm
DEN
- VVI
3 stops31h 33m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1211:49 pm
DEN
- VVI
1 stop27h 01m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:05 pm
DEN
- VVI
1 stop27h 45m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$392
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/119:00 pm
DEN
- VVI
3 stops28h 40m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$403
Find flight deals from Denver to Santa Cruz de la Sierra
Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $653 (United Airlines) |
One-way from | $277 (Kiwi.com) |
Popular in | December |
Cheapest in | October |
Average price | $1,089 |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from Denver to Santa Cruz de la Sierra that are best for you.
Fly from
Fly to
Route
Depart
Return
DenverSanta Cruz de la Sierra
DEN - VVI
DENVVI
Denver Intl
Mon 3/30
11:59 pm-10:50 pm
2 stops20h 51m
Santa Cruz de la Sierra Viru Viru Intl
Tue 4/21
11:48 am-11:43 am
3 stops25h 55m
$653
DenverSanta Cruz de la Sierra
DEN - VVI
DENVVI
Denver Intl
Thu 4/9
7:38 pm-3:40 am
2 stops30h 02m
Santa Cruz de la Sierra Viru Viru Intl
Mon 4/13
11:48 am-10:10 pm
2 stops36h 22m
$653
DenverSanta Cruz de la Sierra
DEN - VVI
DENVVI
Denver Intl
Thu 4/9
10:51 pm-10:42 pm
1 stop21h 51m
Santa Cruz de la Sierra Viru Viru Intl
Sun 4/12
1:15 am-6:25 pm
1 stop19h 10m
$675
DenverSanta Cruz de la Sierra
DEN - VVI
DENVVI
Denver Intl
Sat 7/18
11:59 pm-10:40 pm
2 stops44h 41m
Santa Cruz de la Sierra Viru Viru Intl
Thu 7/23
3:35 am-11:57 pm
2 stops22h 22m
$775
DenverSanta Cruz de la Sierra
DEN - VVI
DENVVI
Denver Intl
Mon 6/15
6:00 am-3:31 am
2 stops19h 31m
Santa Cruz de la Sierra Viru Viru Intl
Tue 6/23
11:47 am-8:22 am
2 stops22h 35m
$882
DenverSanta Cruz de la Sierra
DEN - VVI
DENVVI
Denver Intl
Mon 3/30
10:52 pm-10:50 pm
1 stop21h 58m
Santa Cruz de la Sierra Viru Viru Intl
Tue 4/21
11:48 am-6:25 pm
1 stop32h 37m
$889
DenverSanta Cruz de la Sierra
DEN - VVI
DENVVI
Denver Intl
Tue 4/14
11:59 pm-3:40 am
3 stops25h 41m
$290
DenverSanta Cruz de la Sierra
DEN - VVI
DENVVI
Denver Intl
Sun 4/12
4:15 pm-3:40 am
2 stops33h 25m
$300
DenverSanta Cruz de la Sierra
DEN - VVI
DENVVI
Denver Intl
Thu 4/16
7:50 pm-10:42 pm
2 stops24h 52m
$300
DenverSanta Cruz de la Sierra
DEN - VVI
DENVVI
Denver Intl
Sat 4/11
5:42 pm-3:40 am
2 stops31h 58m
$300
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Denver to Santa Cruz de la Sierra
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santa Cruz de la Sierra in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Denver-Santa Cruz de la Sierra flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Denver-Santa Cruz de la Sierra flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Denver-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Denver-Santa Cruz de la Sierra flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Denver to Santa Cruz de la Sierra
Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Denver with our price prediction graph.
DEN-VVI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to Santa Cruz de la Sierra
Reviews of airlines servicing Santa Cruz de la Sierra
Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated March 3, 2026.
Read through reviews of airlines operating flights from Denver to Santa Cruz de la Sierra, such as Copa Airlines and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.8
Overall
7.5
Entertainment
6.8
Boarding
7.8
Comfort
7.4
Crew
8.1
Reviews
1 / 20
6.0
GoodMaria,Dec 2025
MIA - PTY
Food
6.8
Overall
7.5
Entertainment
6.8
Boarding
7.8
Comfort
7.4
Crew
8.1
Reviews
1 / 20
6.0
GoodMaria,Dec 2025
MIA - PTY
Food
6.8
Overall
7.5
Entertainment
6.8
Boarding
7.8
Comfort
7.4
Crew
8.1
Reviews
1 / 20
6.0
GoodMaria,Dec 2025
MIA - PTY
Related info for your journey
Find useful and relevant information for your journey from Denver to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip to Santa Cruz de la Sierra by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Denver to Santa Cruz de la Sierra, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Denver and Santa Cruz de la Sierra flights
Browse other Denver and Santa Cruz de la Sierra flight options. Last updated on March 3, 2026.
Other flights from Denver
Browse through other flights departing from Denver. Flights are based on user searches made on Cheapflights and were last updated on March 3, 2026.
Popular flight searches
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Top 2 airlines flying from Denver to Santa Cruz de la Sierra
Discover the top 2 airlines that operate flights from Denver to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$581 | Average$667 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$606 | Average$781 | FlexibilityNo cancel fee | On-time70% |