$136+ Cheap flights from St. Louis to Santa Ana, CA (STL - SNA)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SNA
Oct 19 — Oct 261
Round-trip
1 adult, Economy
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One-way
Cheapest flights from St. Louis to Santa AnaExplore the most affordable flight options available from St. Louis to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
Explore the most affordable flight options available from St. Louis to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:30 pm -
1 stop7h 44m
Thu 10/293:55 pm -
1 stop18h 38m
Deal found 9/18![Frontier logo]()
$276
This Cheapflightsfares deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:30 pm -
1 stop7h 44m
Mon 10/2611:38 am -
1 stop5h 37m
Deal found 9/18![Frontier logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:35 pm -
2 stops22h 28m
Sun 10/256:54 pm -
1 stop20h 04m
Deal found 9/17![Multiple Airlines logo]()
$310
This Cheapflightsfares deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/512:17 pm -
1 stop6h 58m
Sun 10/114:08 pm -
1 stop18h 27m
Deal found 9/18![Frontier logo]()
$322
This Cheapflightsfares deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:30 pm -
1 stop7h 44m
Mon 10/1911:38 am -
1 stop5h 37m
Deal found 9/19![Frontier logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:28 pm -
1 stop7h 43m
Mon 11/23:55 pm -
2 stops47h 45m
Deal found 9/14![Frontier logo]()
$328
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:32 am -
1 stop9h 13m
Sat 10/109:12 am -
1 stop7h 08m
Deal found 9/16![American Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:30 pm -
1 stop27h 33m
Thu 10/296:51 pm -
1 stop14h 28m
Deal found 9/15![Multiple Airlines logo]()
$332
This Frontier deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:30 pm -
1 stop7h 44m
Fri 10/2311:38 am -
1 stop5h 37m
Deal found 9/18![Frontier logo]()
$334
Best flights from St. Louis to Santa AnaDiscover carefully curated flight deals from St. Louis to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
Discover carefully curated flight deals from St. Louis to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
This Alaska Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am -
1 stop9h 46m
Thu 11/1912:07 pm -
1 stop9h 52m
Deal found 9/14![Alaska Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:08 pm -
2 stops10h 11m
Wed 11/48:46 am -
1 stop6h 11m
Deal found 9/15![United Airlines logo]()
$458
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:22 pm -
2 stops10h 08m
Mon 11/212:48 pm -
1 stop8h 33m
Deal found 9/18![Delta logo]()
$461
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:45 am -
2 stops11h 37m
Mon 11/212:48 pm -
1 stop8h 33m
Deal found 9/18![Delta logo]()
$461
This Alaska Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:04 am -
2 stops16h 47m
Mon 11/27:06 am -
2 stops11h 36m
Deal found 9/15![Alaska Airlines logo]()
$463
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:39 pm -
1 stop7h 21m
Tue 11/106:50 am -
1 stop8h 07m
Deal found 9/16![United Airlines logo]()
$476
This Alaska Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:42 pm -
2 stops17h 56m
Mon 10/266:47 am -
1 stop15h 12m
Deal found 9/16![Alaska Airlines logo]()
$470
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:00 pm -
1 stop7h 05m
Tue 11/106:51 pm -
2 stops12h 28m
Deal found 9/14![Delta logo]()
$473
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:45 am -
1 stop6h 13m
Fri 10/94:55 pm -
1 stop5h 49m
Deal found 9/18![Delta logo]()
$518
Last-minute flights from St. Louis to Santa AnaDiscover last-minute flight deals from St. Louis to Santa Ana. Data last updated September 19, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Santa Ana. Data last updated September 19, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/512:17 pm -
1 stop6h 58m
Sun 10/114:08 pm -
1 stop18h 27m
Deal found 9/18![Frontier logo]()
$322
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:32 am -
1 stop9h 13m
Sat 10/109:12 am -
1 stop7h 08m
Deal found 9/16![American Airlines logo]()
$329
This Cheapflightsfares deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:30 pm -
1 stop7h 44m
Mon 10/1911:38 am -
1 stop5h 37m
Deal found 9/19![Frontier logo]()
$323
This Frontier deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:30 pm -
1 stop7h 44m
Fri 10/2311:38 am -
1 stop5h 37m
Deal found 9/18![Frontier logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:35 pm -
2 stops22h 28m
Sun 10/256:54 pm -
1 stop20h 04m
Deal found 9/17![Multiple Airlines logo]()
$310
This Cheapflightsfares deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:30 pm -
1 stop7h 44m
Mon 10/2611:38 am -
1 stop5h 37m
Deal found 9/18![Frontier logo]()
$293
This Cheapflightsfares deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:30 pm -
1 stop7h 44m
Thu 10/293:55 pm -
1 stop18h 38m
Deal found 9/18![Frontier logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:30 pm -
1 stop27h 33m
Thu 10/296:51 pm -
1 stop14h 28m
Deal found 9/15![Multiple Airlines logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:28 pm -
1 stop7h 43m
Mon 11/23:55 pm -
2 stops47h 45m
Deal found 9/14![Frontier logo]()
$328
One-way flights from St. Louis to Santa AnaSearch for one-way flight options from St. Louis to Santa Ana. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
Search for one-way flight options from St. Louis to Santa Ana. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
This Frontier deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:14 pm -
1 stop7h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$136
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:54 pm -
1 stop17h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:35 pm -
2 stops25h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Frontier logo]()
$148
This Frontier deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:28 pm -
1 stop7h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:35 pm -
2 stops22h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:35 pm -
2 stops25h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$164
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:30 pm -
1 stop7h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Delta logo]()
$165
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1210:35 am -
2 stops9h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$170
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:40 pm -
2 stops8h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$171
This Frontier deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:14 pm -
1 stop7h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$179
Find flight deals from St. Louis to Santa Ana
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $276 (Cheapflightsfares) |
One-way from | $136 (Frontier) |
Popular in | May |
Cheapest in | April |
Average price | $464 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
Use the filters below to find and compare flights from St. Louis to Santa Ana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Fri 10/23
6:35 pm-5:40 pm
2 stops25h 05m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$164
Quickest round-trip
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Sat 11/14
3:30 pm-8:55 pm
1 stop7h 25m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$165
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Wed 11/18
8:25 am-3:35 pm
1 stop9h 10m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$165
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Tue 11/17
3:30 pm-8:55 pm
1 stop7h 25m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$165
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Fri 10/23
1:30 pm-7:14 pm
1 stop7h 44m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$179
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Wed 11/11
8:00 am-2:14 pm
1 stop8h 14m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$215
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Tue 11/17
8:10 am-9:10 pm
2 stops15h 00m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$220
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Mon 11/9
1:08 pm-10:00 pm
2 stops10h 52m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$244
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Thu 11/12
8:10 am-10:25 pm
2 stops16h 15m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$244
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Sat 9/26
8:10 pm-10:00 am
2 stops39h 50m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$259
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Santa Ana
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santa Ana in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on St. Louis-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santa Ana, California flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Santa Ana
Have a flexible travel schedule? Discover the best time to fly to Santa Ana from St. Louis with our price prediction graph.
STL-SNA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Santa Ana
Prices
More
How far ahead should I book a flight from St. Louis to Santa Ana, California?
To ensure you get the cheapest price possible for a flight from St. Louis to Santa Ana, California, you should look to book at least 12 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from St. Louis to Santa Ana, California?
Currently, April is the cheapest month in which you can book a flight from St. Louis to Santa Ana, California (average of $349). Flying from St. Louis to Santa Ana, California in May is currently the most expensive (average of $790). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Santa Ana, California?
Airfare is below average for this route at the moment.
St. Louis to Santa Ana, California flights typically cost between $401 and $538 in October.The cheapest round-trip price found within the last 5 days was $276 on Frontier (Oct 26-Oct 29).
What’s the top layover airport for flights from St. Louis to Santa Ana, California?
Share of 1-stop round-trip flights from St. Louis to Santa Ana, California chosen by Cheapflights users in the past 12 months, using the same layover each way.
Phoenix (PHX) – chosen by Cheapflights users on 50% of 1-stop itineraries from St. Louis to Santa Ana, California on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to Santa Ana, California?
Average round-trip fare for 1-stop flights from St. Louis to Santa Ana, California, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $341.
What’s the fastest layover option from St. Louis to Santa Ana, California?
Shortest average travel time for 1-stop one-way flights from St. Louis to Santa Ana, California, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Phoenix (PHX) have the shortest average one-way travel time for 1-stop routes: 5h 43m.
Which airport typically offers the quickest layover for flights from St. Louis to Santa Ana, California?
Average layover duration for 1-stop one-way flights from St. Louis to Santa Ana, California, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Phoenix (PHX) offer the fastest connection on this route, with an average layover time of 0h 55m.
Reviews of airlines servicing Santa Ana
Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated September 19, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from St. Louis to Santa Ana to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top 4 airlines flying from St. Louis to Santa Ana
Discover the top 4 airlines that operate flights from St. Louis to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$159 | Average$280 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$326 | Average$470 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$332 | Average$516 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$375 | Average$564 | FlexibilityNo cancel fee | On-time63% |