$105+ Cheap flights from St. Louis to Santa Ana, CA (STL - SNA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SNA
Sep 16 — Sep 231
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Santa Ana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Santa Ana
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to Santa AnaExplore the most affordable flight options available from St. Louis to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
Explore the most affordable flight options available from St. Louis to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:10 pm -
1 stop16h 01m
Mon 11/911:06 am -
1 stop6h 09m
Deal found 8/14![Frontier logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:17 pm -
1 stop6h 58m
Mon 9/284:35 pm -
1 stop16h 57m
Deal found 8/14![Frontier logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:10 pm -
1 stop16h 01m
Tue 11/107:30 am -
1 stop13h 09m
Deal found 8/14![Multiple Airlines logo]()
$233
This Expedia deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:17 pm -
1 stop6h 58m
Mon 9/144:35 pm -
1 stop16h 57m
Deal found 8/16![Frontier logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:17 pm -
1 stop7h 23m
Fri 9/259:30 am -
2 stops31h 47m
Deal found 8/15![Multiple Airlines logo]()
$256
This CheapOair deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:19 pm -
1 stop26h 16m
Sat 10/2411:07 am -
1 stop6h 08m
Deal found 8/12![Frontier logo]()
$262
Best flights from St. Louis to Santa AnaDiscover carefully curated flight deals from St. Louis to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
Discover carefully curated flight deals from St. Louis to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:15 am -
1 stop6h 47m
Fri 10/24:15 pm -
1 stop5h 29m
Deal found 8/12![United Airlines logo]()
$376
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:50 pm -
2 stops8h 05m
Fri 10/22:35 pm -
1 stop5h 10m
Deal found 8/12![Southwest logo]()
$382
This Alaska Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:42 pm -
1 stop18h 47m
Mon 10/196:47 am -
1 stop15h 12m
Deal found 8/16![Alaska Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/52:15 pm -
1 stop5h 53m
Sat 1/97:15 am -
2 stops14h 03m
Deal found 8/16![Delta logo]()
$430
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2412:40 pm -
2 stops8h 40m
Tue 12/2910:05 am -
2 stops7h 35m
Deal found 8/16![Southwest logo]()
$409
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:22 pm -
2 stops10h 08m
Mon 10/266:02 pm -
2 stops12h 51m
Deal found 8/13![Delta logo]()
$440
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:30 am -
2 stops8h 42m
Sat 9/128:55 am -
1 stop5h 39m
Deal found 8/12![United Airlines logo]()
$455
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/258:25 am -
2 stops8h 20m
Tue 12/2910:05 am -
2 stops7h 35m
Deal found 8/16![Southwest logo]()
$457
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:35 am -
2 stops14h 16m
Mon 9/212:17 pm -
1 stop6h 42m
Deal found 8/15![United Airlines logo]()
$462
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:09 pm -
1 stop5h 50m
Wed 12/306:48 am -
1 stop8h 12m
Deal found 8/16![United Airlines logo]()
$473
Last-minute flights from St. Louis to Santa AnaDiscover last-minute flight deals from St. Louis to Santa Ana. Data last updated August 17, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Santa Ana. Data last updated August 17, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:17 pm -
1 stop6h 58m
Mon 9/144:35 pm -
1 stop16h 57m
Deal found 8/16![Frontier logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:29 pm -
2 stops29h 11m
Mon 9/144:35 pm -
1 stop16h 57m
Deal found 8/16![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1310:20 am -
1 stop25h 40m
Tue 9/157:30 am -
1 stop26h 02m
Deal found 8/12![Multiple Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:17 pm -
1 stop6h 58m
Mon 9/284:35 pm -
1 stop16h 57m
Deal found 8/14![Frontier logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:17 pm -
1 stop7h 23m
Fri 9/259:30 am -
2 stops31h 47m
Deal found 8/15![Multiple Airlines logo]()
$256
This Expedia deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:19 pm -
1 stop8h 11m
Fri 10/211:50 am -
1 stop5h 27m
Deal found 8/12![Multiple Airlines logo]()
$308
One-way flights from St. Louis to Santa AnaSearch for one-way flight options from St. Louis to Santa Ana. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
Search for one-way flight options from St. Louis to Santa Ana. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:32 pm -
1 stop26h 03m
Deal found 8/13![Frontier logo]()
$105
This Frontier deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:17 pm -
1 stop6h 58m
Deal found 8/16![Frontier logo]()
$119
This Priceline deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:30 pm -
1 stop7h 44m
Deal found 8/14![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:17 pm -
1 stop7h 23m
Deal found 8/16![Multiple Airlines logo]()
$126
This Priceline deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:16 pm -
1 stop8h 58m
Deal found 8/12![Frontier logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:10 pm -
2 stops21h 38m
Deal found 8/16![Frontier logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1412:17 pm -
1 stop6h 58m
Deal found 8/13![Frontier logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:10 pm -
2 stops47h 30m
Deal found 8/13![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:45 pm -
1 stop25h 00m
Deal found 8/14![Multiple Airlines logo]()
$159
Find flight deals from St. Louis to Santa Ana
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $181 (Kiwi.com) |
One-way from | $105 (Kiwi.com) |
Popular in | May |
Cheapest in | April |
Average price | $440 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
Use the filters below to find and compare flights from St. Louis to Santa Ana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Tue 9/29
6:15 am-11:02 am
1 stop6h 47m
Santa Ana J. Wayne/Orange Cnty
Fri 10/2
4:15 pm-11:44 pm
1 stop5h 29m
$376
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Tue 9/29
2:50 pm-8:55 pm
2 stops8h 05m
Santa Ana J. Wayne/Orange Cnty
Fri 10/2
2:35 pm-9:45 pm
1 stop5h 10m
$382
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Fri 10/16
4:42 pm-9:29 am
1 stop18h 47m
Santa Ana J. Wayne/Orange Cnty
Mon 10/19
6:47 am-11:59 pm
1 stop15h 12m
$389
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Thu 12/24
12:40 pm-7:20 pm
2 stops8h 40m
Santa Ana J. Wayne/Orange Cnty
Tue 12/29
10:05 am-7:40 pm
2 stops7h 35m
$409
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Tue 1/5
2:15 pm-6:08 pm
1 stop5h 53m
Santa Ana J. Wayne/Orange Cnty
Sat 1/9
7:15 am-11:18 pm
2 stops14h 03m
$430
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Fri 10/23
2:22 pm-10:30 pm
2 stops10h 08m
Santa Ana J. Wayne/Orange Cnty
Mon 10/26
6:02 pm-8:53 am
2 stops12h 51m
$440
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Tue 9/1
8:30 am-3:12 pm
2 stops8h 42m
Santa Ana J. Wayne/Orange Cnty
Sat 9/12
8:55 am-4:34 pm
1 stop5h 39m
$455
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Fri 12/25
8:25 am-2:45 pm
2 stops8h 20m
Santa Ana J. Wayne/Orange Cnty
Tue 12/29
10:05 am-7:40 pm
2 stops7h 35m
$457
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Tue 9/15
8:35 am-8:51 pm
2 stops14h 16m
Santa Ana J. Wayne/Orange Cnty
Mon 9/21
2:17 pm-10:59 pm
1 stop6h 42m
$462
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Fri 12/25
6:09 pm-9:59 pm
1 stop5h 50m
Santa Ana J. Wayne/Orange Cnty
Wed 12/30
6:48 am-5:00 pm
1 stop8h 12m
$473
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Santa Ana
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santa Ana in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on St. Louis-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santa Ana, California flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Santa Ana
Have a flexible travel schedule? Discover the best time to fly to Santa Ana from St. Louis with our price prediction graph.
STL-SNA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Santa Ana
Prices
More
How far ahead should I book a flight from St. Louis to Santa Ana, California?
To ensure you get the cheapest price possible for a flight from St. Louis to Santa Ana, California, you should look to book at least 57 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from St. Louis to Santa Ana, California?
Currently, April is the cheapest month in which you can book a flight from St. Louis to Santa Ana, California (average of $349). Flying from St. Louis to Santa Ana, California in May is currently the most expensive (average of $790). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Santa Ana, California?
Airfare is below average for this route at the moment.
St. Louis to Santa Ana, California flights typically cost between $377 and $592 in November.The cheapest round-trip price found within the last 5 days was $181 on Frontier (Nov 6-Nov 9).
What’s the top layover airport for flights from St. Louis to Santa Ana, California?
Share of 1-stop round-trip flights from St. Louis to Santa Ana, California chosen by Cheapflights users in the past 12 months, using the same layover each way.
Phoenix (PHX) – chosen by Cheapflights users on 50% of 1-stop itineraries from St. Louis to Santa Ana, California on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to Santa Ana, California?
Average round-trip fare for 1-stop flights from St. Louis to Santa Ana, California, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $341.
What’s the fastest layover option from St. Louis to Santa Ana, California?
Shortest average travel time for 1-stop one-way flights from St. Louis to Santa Ana, California, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Phoenix (PHX) have the shortest average one-way travel time for 1-stop routes: 5h 43m.
Which airport typically offers the quickest layover for flights from St. Louis to Santa Ana, California?
Average layover duration for 1-stop one-way flights from St. Louis to Santa Ana, California, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Phoenix (PHX) offer the fastest connection on this route, with an average layover time of 0h 55m.
Reviews of airlines servicing Santa Ana
Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated August 17, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from St. Louis to Santa Ana to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santa Ana?
Book flights to Santa Ana if you plan to visit one of these locationsTustin
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from St. Louis
Popular flights
Santa Ana flight routes
Alternative routes for St. Louis to Santa Ana
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santa Ana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Santa Ana by cabin class
Find flights from St. Louis to Santa Ana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Santa Ana flights
Browse other St. Louis and Santa Ana flight options. Last updated on August 17, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on August 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santa Ana
Explore flights to Santa Ana departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 17, 2026.
Top 4 airlines flying from St. Louis to Santa Ana
Discover the top 4 airlines that operate flights from St. Louis to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$159 | Average$280 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$316 | Average$473 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$332 | Average$513 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$360 | Average$571 | FlexibilityNo cancel fee | On-time63% |