$140+ Cheap flights from St. Louis to Santa Ana, CA (STL - SNA)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SNA
Dec 6 — Dec 131
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Santa Ana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Santa Ana
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Cheapest flights from St. Louis to Santa AnaExplore the most affordable flight options available from St. Louis to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2026.
Explore the most affordable flight options available from St. Louis to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:54 pm -
1 stop17h 54m
Fri 12/1112:33 pm -
1 stop20h 24m
Deal found 11/2![Frontier logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:58 pm -
2 stops20h 03m
Fri 12/1112:33 pm -
1 stop20h 24m
Deal found 11/5![Frontier logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:20 pm -
2 stops43h 28m
Fri 12/1112:33 pm -
1 stop20h 24m
Deal found 11/2![Frontier logo]()
$232
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:54 pm -
1 stop17h 54m
Sat 1/94:16 pm -
1 stop27h 21m
Deal found 11/1![Frontier logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:58 pm -
2 stops20h 56m
Sun 12/612:33 pm -
1 stop20h 24m
Deal found 11/6![Frontier logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:13 pm -
2 stops25h 41m
Thu 12/1012:33 pm -
1 stop20h 24m
Deal found 11/2![Frontier logo]()
$279
This CheapOair deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:09 am -
1 stop9h 35m
Thu 12/312:08 pm -
1 stop20h 49m
Deal found 11/2![Frontier logo]()
$290
Best flights from St. Louis to Santa AnaDiscover carefully curated flight deals from St. Louis to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 6, 2026.
Discover carefully curated flight deals from St. Louis to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 6, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/295:15 pm -
1 stop26h 44m
Sun 12/612:33 pm -
1 stop20h 24m
Deal found 11/1![Frontier logo]()
$350
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:15 pm -
1 stop6h 06m
Thu 12/105:15 pm -
1 stop5h 31m
Deal found 11/3![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
1 stop7h 46m
Fri 12/111:00 pm -
1 stop5h 57m
Deal found 11/5![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:25 am -
2 stops8h 20m
Thu 12/109:35 am -
2 stops9h 35m
Deal found 11/2![Southwest logo]()
$409
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/57:05 am -
1 stop6h 58m
Sat 1/911:05 am -
2 stops10h 20m
Deal found 11/5![Delta logo]()
$456
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:40 pm -
2 stops8h 40m
Sun 12/62:15 pm -
1 stop8h 20m
Deal found 11/3![Southwest logo]()
$471
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:26 pm -
2 stops27h 33m
Sun 11/226:44 pm -
2 stops14h 19m
Deal found 11/1![Frontier logo]()
$515
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:00 am -
2 stops12h 43m
Sun 1/241:15 pm -
1 stop7h 30m
Deal found 11/5![Delta logo]()
$503
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:25 am -
1 stop7h 10m
Tue 12/11:50 pm -
1 stop5h 30m
Deal found 11/6![Southwest logo]()
$530
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:15 am -
2 stops8h 05m
Sun 1/34:50 pm -
1 stop6h 55m
Deal found 11/6![Southwest logo]()
$535
Last-minute flights from St. Louis to Santa AnaDiscover last-minute flight deals from St. Louis to Santa Ana. Data last updated November 6, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Santa Ana. Data last updated November 6, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:58 pm -
2 stops20h 56m
Sun 12/612:33 pm -
1 stop20h 24m
Deal found 11/6![Frontier logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:13 pm -
2 stops25h 41m
Thu 12/1012:33 pm -
1 stop20h 24m
Deal found 11/2![Frontier logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:58 pm -
2 stops20h 03m
Fri 12/1112:33 pm -
1 stop20h 24m
Deal found 11/5![Frontier logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:20 pm -
2 stops43h 28m
Fri 12/1112:33 pm -
1 stop20h 24m
Deal found 11/2![Frontier logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:54 pm -
1 stop17h 54m
Fri 12/1112:33 pm -
1 stop20h 24m
Deal found 11/2![Frontier logo]()
$190
This Cheapflightsfares deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:54 pm -
1 stop17h 54m
Sat 1/94:16 pm -
1 stop27h 21m
Deal found 11/3![Frontier logo]()
$242
One-way flights from St. Louis to Santa AnaSearch for one-way flight options from St. Louis to Santa Ana. Find affordable one-way fares based on user searches. Data last updated November 6, 2026.
Search for one-way flight options from St. Louis to Santa Ana. Find affordable one-way fares based on user searches. Data last updated November 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:21 pm -
2 stops41h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:02 pm -
2 stops29h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$160
This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:37 pm -
2 stops24h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Frontier logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:18 pm -
2 stops22h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$191
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/191:28 pm -
1 stop7h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$198
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/305:00 am -
1 stop7h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:20 pm -
2 stops43h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Frontier logo]()
$203
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:04 pm -
1 stop21h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Frontier logo]()
$211
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/81:40 pm -
1 stop6h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Southwest logo]()
$212
This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1312:14 pm -
1 stop7h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Frontier logo]()
$220
Find flight deals from St. Louis to Santa Ana
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $190 (Kiwi.com) |
One-way from | $140 (Kiwi.com) |
Popular in | May |
Cheapest in | April |
Average price | $516 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 6, 2026.
Use the filters below to find and compare flights from St. Louis to Santa Ana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Wed 12/30
6:21 pm-10:09 am
2 stops41h 48m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$140
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Mon 12/7
12:02 pm-3:03 pm
2 stops29h 01m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$160
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Wed 12/30
5:00 am-10:04 am
1 stop7h 04m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$200
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Thu 12/31
5:30 am-9:20 am
1 stop5h 50m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$200
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Wed 12/16
2:15 pm-6:21 pm
1 stop6h 06m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$200
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Mon 12/7
3:00 pm-9:45 pm
1 stop8h 45m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$200
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Tue 12/8
1:40 pm-6:30 pm
1 stop6h 50m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$212
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Fri 11/13
12:14 pm-6:05 pm
1 stop7h 51m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$220
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Fri 11/20
3:04 pm-5:24 pm
1 stop28h 20m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$270
Quickest round-trip
St. LouisSanta Ana
STL Lambert-St Louis - SNA Santa Ana J. Wayne/Orange Cnty
STLSNA
Lambert-St Louis
Wed 11/18
5:55 am-9:25 am
1 stop5h 30m
Santa Ana J. Wayne/Orange Cnty
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$314
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Santa Ana
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santa Ana in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on St. Louis-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santa Ana, California flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Santa Ana
Have a flexible travel schedule? Discover the best time to fly to Santa Ana from St. Louis with our price prediction graph.
STL-SNA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Santa Ana
Prices
More
How far ahead should I book a flight from St. Louis to Santa Ana, California?
To ensure you get the cheapest price possible for a flight from St. Louis to Santa Ana, California, you should look to book at least 57 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from St. Louis to Santa Ana, California?
Currently, April is the cheapest month in which you can book a flight from St. Louis to Santa Ana, California (average of $349). Flying from St. Louis to Santa Ana, California in May is currently the most expensive (average of $790). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Santa Ana, California?
Airfare is below average for this route at the moment.
St. Louis to Santa Ana, California flights typically cost between $506 and $521 in December.The cheapest round-trip price found within the last 5 days was $190 on Frontier (Dec 9-Dec 11).
What’s the top layover airport for flights from St. Louis to Santa Ana, California?
Share of 1-stop round-trip flights from St. Louis to Santa Ana, California chosen by Cheapflights users in the past 12 months, using the same layover each way.
Chicago (ORD) – chosen by Cheapflights users on 33% of 1-stop itineraries from St. Louis to Santa Ana, California on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to Santa Ana, California?
Average round-trip fare for 1-stop flights from St. Louis to Santa Ana, California, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $341.
What’s the fastest layover option from St. Louis to Santa Ana, California?
Shortest average travel time for 1-stop one-way flights from St. Louis to Santa Ana, California, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Phoenix (PHX) have the shortest average one-way travel time for 1-stop routes: 5h 43m.
Which airport typically offers the quickest layover for flights from St. Louis to Santa Ana, California?
Average layover duration for 1-stop one-way flights from St. Louis to Santa Ana, California, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Phoenix (PHX) offer the fastest connection on this route, with an average layover time of 0h 55m.
Reviews of airlines servicing Santa Ana
Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated November 6, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from St. Louis to Santa Ana to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santa Ana?
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Alternative routes for St. Louis to Santa Ana
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St. Louis and Santa Ana flights
Browse other St. Louis and Santa Ana flight options. Last updated on November 6, 2026.
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Other flights to Santa Ana
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Top 3 airlines flying from St. Louis to Santa Ana
Discover the top 3 airlines that operate flights from St. Louis to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$332 | Average$518 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$336 | Average$502 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$379 | Average$567 | FlexibilityNo cancel fee | On-time63% |