$145+ Cheap flights from St. Louis to Santa Ana, CA (STL - SNA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SNA
Sep 3 — Sep 101
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from St. Louis to Santa AnaExplore the most affordable flight options available from St. Louis to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 4, 2026.
Explore the most affordable flight options available from St. Louis to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:10 pm -
1 stop16h 01m
Sun 11/111:06 am -
1 stop6h 09m
Deal found 8/3![Frontier logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:10 pm -
1 stop16h 01m
Sun 11/811:06 am -
1 stop6h 09m
Deal found 8/2![Frontier logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:10 pm -
1 stop16h 01m
Mon 11/211:06 am -
1 stop6h 09m
Deal found 8/1![Frontier logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:10 pm -
1 stop16h 02m
Sat 10/2411:07 am -
1 stop6h 08m
Deal found 8/2![Frontier logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:10 pm -
1 stop16h 01m
Mon 11/94:46 pm -
1 stop27h 53m
Deal found 8/2![Frontier logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:35 am -
2 stops33h 58m
Sun 11/111:06 am -
1 stop6h 09m
Deal found 8/3![Frontier logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:35 am -
2 stops25h 36m
Sun 11/811:06 am -
1 stop6h 09m
Deal found 8/2![Frontier logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/131:02 pm -
1 stop24h 03m
Tue 9/157:30 am -
1 stop26h 02m
Deal found 7/31![Multiple Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:10 pm -
1 stop16h 01m
Tue 11/107:30 am -
1 stop13h 09m
Deal found 8/2![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:58 pm -
1 stop14h 26m
Mon 8/319:09 am -
1 stop8h 04m
Deal found 8/1![Frontier logo]()
$281
Best flights from St. Louis to Santa AnaDiscover carefully curated flight deals from St. Louis to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 4, 2026.
Discover carefully curated flight deals from St. Louis to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:45 pm -
1 stop19h 46m
Wed 9/97:30 am -
1 stop25h 47m
Deal found 8/3![Multiple Airlines logo]()
$376
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/55:30 pm -
1 stop6h 15m
Sat 1/96:45 am -
2 stops7h 20m
Deal found 7/30![Southwest logo]()
$380
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:22 pm -
2 stops10h 08m
Mon 10/196:02 pm -
2 stops12h 51m
Deal found 7/30![Delta logo]()
$413
This Alaska Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:29 am -
1 stop9h 20m
Thu 9/241:09 pm -
1 stop8h 50m
Deal found 8/3![Alaska Airlines logo]()
$429
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:35 am -
2 stops8h 00m
Wed 9/93:40 pm -
1 stop5h 10m
Deal found 8/3![Southwest logo]()
$390
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 am -
1 stop5h 20m
Wed 9/97:30 am -
1 stop8h 25m
Deal found 8/3![Southwest logo]()
$407
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:00 pm -
1 stop7h 05m
Tue 11/106:59 pm -
2 stops12h 20m
Deal found 8/3![Delta logo]()
$468
This Alaska Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:02 am -
1 stop9h 21m
Mon 10/198:07 am -
1 stop13h 52m
Deal found 8/1![Alaska Airlines logo]()
$473
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 am -
1 stop5h 20m
Tue 9/83:40 pm -
1 stop5h 10m
Deal found 8/3![Southwest logo]()
$429
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:20 am -
2 stops8h 35m
Mon 11/29:15 am -
2 stops8h 35m
Deal found 8/1![Southwest logo]()
$461
Last-minute flights from St. Louis to Santa AnaDiscover last-minute flight deals from St. Louis to Santa Ana. Data last updated August 4, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Santa Ana. Data last updated August 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:45 pm -
2 stops16h 09m
Mon 8/319:09 am -
1 stop8h 04m
Deal found 8/1![Frontier logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:58 pm -
1 stop14h 26m
Mon 8/319:09 am -
1 stop8h 04m
Deal found 8/1![Frontier logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:58 pm -
1 stop14h 26m
Thu 9/39:39 am -
1 stop7h 34m
Deal found 8/1![Frontier logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:58 pm -
1 stop14h 26m
Sun 8/306:39 pm -
2 stops20h 43m
Deal found 8/1![Frontier logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:45 pm -
1 stop22h 03m
Mon 8/319:09 am -
1 stop8h 04m
Deal found 8/1![Frontier logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:45 pm -
1 stop22h 03m
Thu 9/39:39 am -
1 stop7h 34m
Deal found 8/1![Frontier logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:17 pm -
2 stops21h 25m
Thu 9/39:39 am -
1 stop7h 34m
Deal found 8/1![Frontier logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:45 pm -
1 stop22h 16m
Thu 9/39:39 am -
1 stop7h 34m
Deal found 8/1![Multiple Airlines logo]()
$308
This Expedia deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:17 pm -
1 stop6h 58m
Mon 9/144:35 pm -
1 stop16h 57m
Deal found 7/31![Frontier logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/131:02 pm -
1 stop24h 03m
Tue 9/157:30 am -
1 stop26h 02m
Deal found 7/31![Multiple Airlines logo]()
$278
One-way flights from St. Louis to Santa AnaSearch for one-way flight options from St. Louis to Santa Ana. Find affordable one-way fares based on user searches. Data last updated August 4, 2026.
Search for one-way flight options from St. Louis to Santa Ana. Find affordable one-way fares based on user searches. Data last updated August 4, 2026.
This Frontier deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1412:17 pm -
1 stop6h 58m
Deal found 7/31![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:45 pm -
2 stops42h 20m
Deal found 7/30![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:17 pm -
2 stops45h 25m
Deal found 8/1![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:45 pm -
3 stops41h 06m
Deal found 7/30![Multiple Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:19 pm -
1 stop23h 44m
Deal found 8/2![Multiple Airlines logo]()
$180
This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:08 pm -
1 stop16h 20m
Deal found 7/30![Frontier logo]()
$185
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/81:36 pm -
1 stop7h 23m
Deal found 7/30![United Airlines logo]()
$188
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/158:25 am -
2 stops8h 25m
Deal found 7/30![Southwest logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:17 pm -
2 stops48h 48m
Deal found 8/3![Frontier logo]()
$213
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:20 am -
1 stop8h 34m
Deal found 7/31![Delta logo]()
$215
Find flight deals from St. Louis to Santa Ana
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $228 (Kiwi.com) |
One-way from | $145 (Frontier) |
Popular in | May |
Cheapest in | November |
Average price | $440 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from St. Louis to Santa Ana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Wed 9/2
6:45 pm-12:31 pm
1 stop19h 46m
Santa Ana J. Wayne/Orange Cnty
Wed 9/9
7:30 am-11:17 am
1 stop25h 47m
$376
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Tue 1/5
5:30 pm-9:45 pm
1 stop6h 15m
Santa Ana J. Wayne/Orange Cnty
Sat 1/9
6:45 am-4:05 pm
2 stops7h 20m
$380
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Wed 9/9
7:35 am-1:35 pm
2 stops8h 00m
Santa Ana J. Wayne/Orange Cnty
Wed 9/9
3:40 pm-10:50 pm
1 stop5h 10m
$390
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Mon 9/7
6:00 am-9:20 am
1 stop5h 20m
Santa Ana J. Wayne/Orange Cnty
Wed 9/9
7:30 am-5:55 pm
1 stop8h 25m
$407
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Fri 10/16
2:22 pm-10:30 pm
2 stops10h 08m
Santa Ana J. Wayne/Orange Cnty
Mon 10/19
6:02 pm-8:53 am
2 stops12h 51m
$413
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Mon 9/21
6:29 am-1:49 pm
1 stop9h 20m
Santa Ana J. Wayne/Orange Cnty
Thu 9/24
1:09 pm-11:59 pm
1 stop8h 50m
$429
Quickest round-trip
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Mon 9/7
6:00 am-9:20 am
1 stop5h 20m
Santa Ana J. Wayne/Orange Cnty
Tue 9/8
3:40 pm-10:50 pm
1 stop5h 10m
$429
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Thu 10/29
10:20 am-4:55 pm
2 stops8h 35m
Santa Ana J. Wayne/Orange Cnty
Mon 11/2
9:15 am-7:50 pm
2 stops8h 35m
$461
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Fri 11/6
5:00 pm-10:05 pm
1 stop7h 05m
Santa Ana J. Wayne/Orange Cnty
Tue 11/10
6:59 pm-9:19 am
2 stops12h 20m
$468
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Fri 10/16
7:02 am-2:23 pm
1 stop9h 21m
Santa Ana J. Wayne/Orange Cnty
Mon 10/19
8:07 am-11:59 pm
1 stop13h 52m
$473
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Santa Ana
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santa Ana in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on St. Louis-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santa Ana, California flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Santa Ana
Have a flexible travel schedule? Discover the best time to fly to Santa Ana from St. Louis with our price prediction graph.
STL-SNA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Santa Ana
Prices
More
How far ahead should I book a flight from St. Louis to Santa Ana, California?
To ensure you get the cheapest price possible for a flight from St. Louis to Santa Ana, California, you should look to book at least 57 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from St. Louis to Santa Ana, California?
Currently, November is the cheapest month in which you can book a flight from St. Louis to Santa Ana, California (average of $332). Flying from St. Louis to Santa Ana, California in May is currently the most expensive (average of $790). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Santa Ana, California?
Airfare is below average for this route at the moment.
St. Louis to Santa Ana, California flights typically cost between $377 and $592 in October.The cheapest round-trip price found within the last 5 days was $228 on Frontier (Oct 29-Nov 1).
What’s the top layover airport for flights from St. Louis to Santa Ana, California?
Share of 1-stop round-trip flights from St. Louis to Santa Ana, California chosen by Cheapflights users in the past 12 months, using the same layover each way.
Phoenix (PHX) – chosen by Cheapflights users on 50% of 1-stop itineraries from St. Louis to Santa Ana, California on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to Santa Ana, California?
Average round-trip fare for 1-stop flights from St. Louis to Santa Ana, California, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $341.
What’s the fastest layover option from St. Louis to Santa Ana, California?
Shortest average travel time for 1-stop one-way flights from St. Louis to Santa Ana, California, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Phoenix (PHX) have the shortest average one-way travel time for 1-stop routes: 5h 43m.
Which airport typically offers the quickest layover for flights from St. Louis to Santa Ana, California?
Average layover duration for 1-stop one-way flights from St. Louis to Santa Ana, California, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Phoenix (PHX) offer the fastest connection on this route, with an average layover time of 0h 55m.
Reviews of airlines servicing Santa Ana
Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated August 4, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from St. Louis to Santa Ana to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
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St. Louis and Santa Ana flights
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Top 4 airlines flying from St. Louis to Santa Ana
Discover the top 4 airlines that operate flights from St. Louis to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$159 | Average$270 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$296 | Average$458 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$332 | Average$576 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$332 | Average$513 | FlexibilityNo cancel fee | On-time69% |