$111+ Cheap flights from St. Louis to Santa Ana, CA (STL - SNA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SNA
Jun 14 — Jun 211
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Santa Ana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Santa Ana
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Cheapest flights from St. Louis to Santa AnaExplore the most affordable flight options available from St. Louis to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 15, 2026.
Explore the most affordable flight options available from St. Louis to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 15, 2026.
This Frontier deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:06 pm
STL
- SNA
1 stop17h 13m
Frontier
Fri 6/128:10 pm
SNA
- STL
1 stop15h 56m
Frontier
Deal found 5/10![Frontier logo]()
$246
This Gotogate deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:21 pm
STL
- SNA
1 stop17h 39m
Frontier
Mon 8/318:10 pm
SNA
- STL
1 stop19h 58m
Frontier
Deal found 5/11![Frontier logo]()
$274
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:06 pm
STL
- SNA
1 stop17h 13m
Frontier
Sun 6/78:10 pm
SNA
- STL
1 stop22h 01m
Frontier
Deal found 5/11![Frontier logo]()
$276
This Booking.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/262:56 pm
STL
- SNA
1 stop23h 38m
Frontier
Mon 6/298:10 pm
SNA
- STL
1 stop20h 41m
Frontier
Deal found 5/12![Frontier logo]()
$282
This Frontier deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2712:46 pm
STL
- SNA
1 stop6h 49m
Frontier
Mon 9/2811:07 am
SNA
- STL
1 stop6h 08m
Frontier
Deal found 5/12![Frontier logo]()
$290
This Booking.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:51 pm
STL
- SNA
1 stop19h 28m
Frontier
Fri 6/58:10 pm
SNA
- STL
1 stop19h 24m
Frontier
Deal found 5/13![Frontier logo]()
$292
This Booking.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:46 pm
STL
- SNA
1 stop18h 48m
Frontier
Mon 6/298:10 pm
SNA
- STL
1 stop20h 41m
Frontier
Deal found 5/14![Frontier logo]()
$301
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:08 pm
STL
- SNA
1 stop15h 01m
Frontier
Sun 5/319:54 am
SNA
- STL
1 stop7h 29m
Frontier
Deal found 5/11![Frontier logo]()
$302
This Frontier deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:46 pm
STL
- SNA
1 stop6h 49m
Frontier
Thu 10/111:07 am
SNA
- STL
1 stop6h 08m
Frontier
Deal found 5/12![Frontier logo]()
$310
This Booking.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:06 pm
STL
- SNA
1 stop17h 13m
Frontier
Mon 6/88:10 pm
SNA
- STL
1 stop18h 55m
Frontier
Deal found 5/14![Frontier logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:46 pm
STL
- SNA
1 stop18h 48m
Frontier
Mon 6/228:10 pm
SNA
- STL
2 stops21h 13m
Frontier
Deal found 5/14![Frontier logo]()
$315
Best flights from St. Louis to Santa AnaDiscover carefully curated flight deals from St. Louis to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 15, 2026.
Discover carefully curated flight deals from St. Louis to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 15, 2026.
This Alaska Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/283:17 pm
STL
- SNA
1 stop8h 13m
Alaska Airlines
Tue 9/297:09 am
SNA
- STL
1 stop7h 54m
Alaska Airlines
Deal found 5/12![Alaska Airlines logo]()
$425
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:15 pm
STL
- SNA
1 stop5h 58m
Delta
Sat 9/268:00 am
SNA
- STL
1 stop6h 45m
Delta
Deal found 5/12![Delta logo]()
$425
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:10 am
STL
- SNA
1 stop5h 57m
United Airlines
Thu 6/114:00 pm
SNA
- STL
1 stop5h 57m
United Airlines
Deal found 5/14![United Airlines logo]()
$443
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:08 pm
STL
- SNA
1 stop15h 01m
Multiple Airlines
Mon 6/17:30 am
SNA
- STL
2 stops33h 53m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$461
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:25 pm
STL
- SNA
2 stops7h 50m
Southwest
Thu 10/228:35 am
SNA
- STL
2 stops8h 30m
Southwest
Deal found 5/10![Southwest logo]()
$462
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/153:57 pm
STL
- SNA
1 stop6h 27m
Delta
Mon 6/225:03 pm
SNA
- STL
1 stop5h 40m
Delta
Deal found 5/14![Delta logo]()
$443
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:45 pm
STL
- SNA
2 stops7h 10m
Southwest
Sun 8/22:35 pm
SNA
- STL
1 stop8h 20m
Southwest
Deal found 5/14![Southwest logo]()
$475
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:11 pm
STL
- SNA
1 stop7h 23m
Delta
Wed 6/35:05 pm
SNA
- STL
1 stop5h 25m
Delta
Deal found 5/13![Delta logo]()
$452
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/285:45 am
STL
- SNA
1 stop5h 30m
Southwest
Sun 7/52:35 pm
SNA
- STL
1 stop8h 20m
Southwest
Deal found 5/13![Southwest logo]()
$497
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/303:50 pm
STL
- SNA
1 stop6h 17m
Delta
Sat 9/512:20 pm
SNA
- STL
1 stop9h 17m
Delta
Deal found 5/10![Delta logo]()
$470
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:45 pm
STL
- SNA
2 stops9h 40m
Southwest
Fri 6/52:30 pm
SNA
- STL
2 stops7h 40m
Southwest
Deal found 5/13![Southwest logo]()
$509
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:20 pm
STL
- SNA
2 stops9h 00m
Southwest
Fri 6/122:30 pm
SNA
- STL
2 stops7h 40m
Southwest
Deal found 5/10![Southwest logo]()
$536
Last-minute flights from St. Louis to Santa AnaDiscover last-minute flight deals from St. Louis to Santa Ana. Data last updated May 15, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Santa Ana. Data last updated May 15, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:08 pm
STL
- SNA
1 stop15h 01m
Frontier
Sun 5/319:54 am
SNA
- STL
1 stop7h 29m
Frontier
Deal found 5/11![Frontier logo]()
$302
This Booking.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:51 pm
STL
- SNA
1 stop19h 28m
Frontier
Fri 6/58:10 pm
SNA
- STL
1 stop19h 24m
Frontier
Deal found 5/13![Frontier logo]()
$292
This Frontier deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:06 pm
STL
- SNA
1 stop17h 13m
Frontier
Fri 6/128:10 pm
SNA
- STL
1 stop15h 56m
Frontier
Deal found 5/10![Frontier logo]()
$246
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:06 pm
STL
- SNA
1 stop17h 13m
Frontier
Sun 6/78:10 pm
SNA
- STL
1 stop22h 01m
Frontier
Deal found 5/11![Frontier logo]()
$276
This Booking.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:06 pm
STL
- SNA
1 stop17h 13m
Frontier
Mon 6/88:10 pm
SNA
- STL
1 stop18h 55m
Frontier
Deal found 5/14![Frontier logo]()
$311
This Booking.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:08 pm
STL
- SNA
1 stop15h 01m
Frontier
Mon 6/88:10 pm
SNA
- STL
1 stop18h 55m
Frontier
Deal found 5/13![Frontier logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/54:19 pm
STL
- SNA
1 stop22h 06m
Multiple Airlines
Mon 6/88:10 pm
SNA
- STL
2 stops21h 13m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:46 pm
STL
- SNA
1 stop18h 48m
Frontier
Mon 6/228:10 pm
SNA
- STL
2 stops21h 13m
Frontier
Deal found 5/14![Frontier logo]()
$315
This Booking.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:46 pm
STL
- SNA
1 stop18h 48m
Frontier
Mon 6/298:10 pm
SNA
- STL
1 stop20h 41m
Frontier
Deal found 5/14![Frontier logo]()
$301
This Booking.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/262:56 pm
STL
- SNA
1 stop23h 38m
Frontier
Mon 6/298:10 pm
SNA
- STL
1 stop20h 41m
Frontier
Deal found 5/12![Frontier logo]()
$282
One-way flights from St. Louis to Santa AnaSearch for one-way flight options from St. Louis to Santa Ana. Find affordable one-way fares based on user searches. Data last updated May 15, 2026.
Search for one-way flight options from St. Louis to Santa Ana. Find affordable one-way fares based on user searches. Data last updated May 15, 2026.
This CheapOair deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:03 pm
STL
- SNA
1 stop19h 31m
Frontier
Deal found 5/12![Frontier logo]()
$111
This CheapOair deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:38 pm
STL
- SNA
1 stop15h 51m
Frontier
Deal found 5/12![Frontier logo]()
$131
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/52:52 pm
STL
- SNA
1 stop23h 44m
Frontier
Deal found 5/11![Frontier logo]()
$136
This CheapOair deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:08 pm
STL
- SNA
1 stop15h 01m
Frontier
Deal found 5/12![Frontier logo]()
$141
This Frontier deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:46 pm
STL
- SNA
1 stop6h 49m
Frontier
Deal found 5/14![Frontier logo]()
$149
This CheapOair deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/187:38 pm
STL
- SNA
1 stop14h 31m
Frontier
Deal found 5/10![Frontier logo]()
$151
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:08 pm
STL
- SNA
1 stop15h 01m
Frontier
Deal found 5/11![Frontier logo]()
$157
This Booking.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/238:21 pm
STL
- SNA
1 stop17h 39m
Frontier
Deal found 5/14![Frontier logo]()
$167
This CheapOair deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:51 pm
STL
- SNA
1 stop19h 28m
Frontier
Deal found 5/12![Frontier logo]()
$171
This Booking.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:08 pm
STL
- SNA
1 stop15h 01m
Frontier
Deal found 5/13![Frontier logo]()
$177
Find flight deals from St. Louis to Santa Ana
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $246 (Frontier) |
One-way from | $111 (CheapOair) |
Popular in | May |
Cheapest in | November |
Average price | $790 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2026.
Use the filters below to find and compare flights from St. Louis to Santa Ana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Mon 9/28
3:17 pm-9:30 pm
1 stop8h 13m
Santa Ana J. Wayne/Orange Cnty
Tue 9/29
7:09 am-5:03 pm
1 stop7h 54m
$425
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Wed 9/23
2:15 pm-6:13 pm
1 stop5h 58m
Santa Ana J. Wayne/Orange Cnty
Sat 9/26
8:00 am-4:45 pm
1 stop6h 45m
$425
Quickest round-trip
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Mon 6/8
5:10 am-9:07 am
1 stop5h 57m
Santa Ana J. Wayne/Orange Cnty
Thu 6/11
4:00 pm-11:57 pm
1 stop5h 57m
$443
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Mon 6/15
3:57 pm-8:24 pm
1 stop6h 27m
Santa Ana J. Wayne/Orange Cnty
Mon 6/22
5:03 pm-12:43 am
1 stop5h 40m
$443
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Thu 5/28
3:11 pm-8:34 pm
1 stop7h 23m
Santa Ana J. Wayne/Orange Cnty
Wed 6/3
5:05 pm-12:30 am
1 stop5h 25m
$452
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Fri 5/29
8:08 pm-9:09 am
1 stop15h 01m
Santa Ana J. Wayne/Orange Cnty
Mon 6/1
7:30 am-7:23 pm
2 stops33h 53m
$461
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Tue 10/20
4:25 pm-10:15 pm
2 stops7h 50m
Santa Ana J. Wayne/Orange Cnty
Thu 10/22
8:35 am-7:05 pm
2 stops8h 30m
$462
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Sun 8/30
3:50 pm-8:07 pm
1 stop6h 17m
Santa Ana J. Wayne/Orange Cnty
Sat 9/5
12:20 pm-11:37 pm
1 stop9h 17m
$470
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Sat 7/25
4:45 pm-9:55 pm
2 stops7h 10m
Santa Ana J. Wayne/Orange Cnty
Sun 8/2
2:35 pm-12:55 am
1 stop8h 20m
$475
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Sun 6/28
5:45 am-9:15 am
1 stop5h 30m
Santa Ana J. Wayne/Orange Cnty
Sun 7/5
2:35 pm-12:55 am
1 stop8h 20m
$497
Showing 1-10 of 23 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Santa Ana
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santa Ana in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santa Ana, California flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Santa Ana
Have a flexible travel schedule? Discover the best time to fly to Santa Ana from St. Louis with our price prediction graph.
STL-SNA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Santa Ana
Prices
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How far ahead should I book a flight from St. Louis to Santa Ana, California?
To ensure you get the cheapest price possible for a flight from St. Louis to Santa Ana, California, you should look to book at least 76 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from St. Louis to Santa Ana, California?
Currently, November is the cheapest month in which you can book a flight from St. Louis to Santa Ana, California (average of $345). Flying from St. Louis to Santa Ana, California in May is currently the most expensive (average of $790). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Santa Ana, California?
What’s the top layover airport for flights from St. Louis to Santa Ana, California?
Share of 1-stop round-trip flights from St. Louis to Santa Ana, California chosen by Cheapflights users in the past 12 months, using the same layover each way.
Denver (DEN) – chosen by Cheapflights users on 67% of 1-stop itineraries from St. Louis to Santa Ana, California on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to Santa Ana, California?
Average round-trip fare for 1-stop flights from St. Louis to Santa Ana, California, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $341.
What’s the fastest layover option from St. Louis to Santa Ana, California?
Shortest average travel time for 1-stop one-way flights from St. Louis to Santa Ana, California, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Denver (DEN) have the shortest average one-way travel time for 1-stop routes: 5h 59m.
Which airport typically offers the quickest layover for flights from St. Louis to Santa Ana, California?
Average layover duration for 1-stop one-way flights from St. Louis to Santa Ana, California, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Denver (DEN) offer the fastest connection on this route, with an average layover time of 0h 55m.
Reviews of airlines servicing Santa Ana
Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated May 15, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from St. Louis to Santa Ana to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Book flights to Santa Ana if you plan to visit one of these locationsTustin
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St. Louis and Santa Ana flights
Browse other St. Louis and Santa Ana flight options. Last updated on May 15, 2026.
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Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on May 15, 2026.
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Top 4 airlines flying from St. Louis to Santa Ana
Discover the top 4 airlines that operate flights from St. Louis to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$159 | Average$280 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$278 | Average$411 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$286 | Average$491 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$316 | Average$564 | FlexibilityNo cancel fee | On-time63% |