$121+ Cheap flights from St. Louis to Santa Ana, CA (STL - SNA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SNA
Aug 22 — Aug 291
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Santa Ana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Santa Ana
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to Santa AnaExplore the most affordable flight options available from St. Louis to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
Explore the most affordable flight options available from St. Louis to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
This Expedia deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:46 pm
STL
- SNA
1 stop6h 49m
Frontier
Mon 9/144:50 pm
SNA
- STL
1 stop17h 01m
Frontier
Deal found 7/20![Frontier logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:58 pm
STL
- SNA
1 stop14h 26m
Frontier
Sun 9/1311:07 am
SNA
- STL
2 stops44h 33m
Frontier
Deal found 7/20![Frontier logo]()
$261
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:03 pm
STL
- SNA
1 stop19h 28m
Frontier
Mon 8/177:53 pm
SNA
- STL
1 stop19h 57m
Frontier
Deal found 7/22![Frontier logo]()
$273
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:08 pm
STL
- SNA
1 stop16h 20m
Frontier
Sat 8/157:53 pm
SNA
- STL
1 stop20h 22m
Frontier
Deal found 7/22![Frontier logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:08 pm
STL
- SNA
1 stop13h 57m
Frontier
Thu 8/209:39 am
SNA
- STL
1 stop7h 34m
Frontier
Deal found 7/21![Frontier logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:58 pm
STL
- SNA
1 stop14h 26m
Frontier
Sun 8/237:53 pm
SNA
- STL
2 stops21h 20m
Frontier
Deal found 7/22![Frontier logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:35 am
STL
- SNA
2 stops28h 57m
Frontier
Mon 9/2811:07 am
SNA
- STL
1 stop6h 08m
Frontier
Deal found 7/22![Frontier logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:08 pm
STL
- SNA
2 stops21h 12m
Frontier
Mon 8/179:03 am
SNA
- STL
1 stop8h 20m
Frontier
Deal found 7/18![Frontier logo]()
$301
This Frontier deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:46 pm
STL
- SNA
1 stop6h 49m
Frontier
Mon 9/2811:07 am
SNA
- STL
1 stop6h 08m
Frontier
Deal found 7/18![Frontier logo]()
$309
Best flights from St. Louis to Santa AnaDiscover carefully curated flight deals from St. Louis to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
Discover carefully curated flight deals from St. Louis to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:56 pm
STL
- SNA
1 stop8h 59m
United Airlines
Thu 11/261:06 pm
SNA
- STL
1 stop5h 28m
United Airlines
Deal found 7/21![United Airlines logo]()
$375
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:35 am
STL
- SNA
1 stop5h 35m
Southwest
Tue 12/18:25 am
SNA
- STL
1 stop4h 55m
Southwest
Deal found 7/21![Southwest logo]()
$375
This Alaska Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/193:04 pm
STL
- SNA
1 stop8h 26m
Alaska Airlines
Wed 8/267:11 am
SNA
- STL
1 stop7h 59m
Alaska Airlines
Deal found 7/19![Alaska Airlines logo]()
$449
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:55 am
STL
- SNA
2 stops9h 55m
Southwest
Sat 8/156:45 am
SNA
- STL
2 stops6h 45m
Southwest
Deal found 7/18![Southwest logo]()
$429
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:50 pm
STL
- SNA
2 stops8h 05m
Southwest
Sat 8/156:45 am
SNA
- STL
2 stops6h 45m
Southwest
Deal found 7/22![Southwest logo]()
$429
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:00 am
STL
- SNA
1 stop5h 50m
United Airlines
Thu 8/134:14 pm
SNA
- STL
1 stop5h 17m
United Airlines
Deal found 7/20![United Airlines logo]()
$475
This Alaska Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:08 pm
STL
- SNA
1 stop17h 38m
Alaska Airlines
Thu 9/176:46 am
SNA
- STL
2 stops15h 13m
Alaska Airlines
Deal found 7/22![Alaska Airlines logo]()
$477
This Alaska Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:29 am
STL
- SNA
1 stop9h 23m
Alaska Airlines
Sat 9/267:11 am
SNA
- STL
1 stop7h 59m
Alaska Airlines
Deal found 7/22![Alaska Airlines logo]()
$485
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:00 am
STL
- SNA
2 stops7h 55m
Southwest
Mon 10/1912:15 pm
SNA
- STL
2 stops9h 10m
Southwest
Deal found 7/20![Southwest logo]()
$451
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/102:20 pm
STL
- SNA
2 stops8h 50m
Southwest
Mon 8/176:45 am
SNA
- STL
2 stops8h 55m
Southwest
Deal found 7/18![Southwest logo]()
$459
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/132:20 pm
STL
- SNA
2 stops8h 50m
Southwest
Sun 8/165:45 pm
SNA
- STL
1 stop5h 25m
Southwest
Deal found 7/22![Southwest logo]()
$484
Last-minute flights from St. Louis to Santa AnaDiscover last-minute flight deals from St. Louis to Santa Ana. Data last updated July 23, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Santa Ana. Data last updated July 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:08 pm
STL
- SNA
2 stops21h 12m
Frontier
Mon 8/179:03 am
SNA
- STL
1 stop8h 20m
Frontier
Deal found 7/18![Frontier logo]()
$301
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:03 pm
STL
- SNA
1 stop19h 28m
Frontier
Mon 8/177:53 pm
SNA
- STL
1 stop19h 57m
Frontier
Deal found 7/22![Frontier logo]()
$273
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:08 pm
STL
- SNA
1 stop16h 20m
Frontier
Sat 8/157:53 pm
SNA
- STL
1 stop20h 22m
Frontier
Deal found 7/22![Frontier logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:08 pm
STL
- SNA
1 stop13h 57m
Frontier
Thu 8/209:39 am
SNA
- STL
1 stop7h 34m
Frontier
Deal found 7/21![Frontier logo]()
$281
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:10 pm
STL
- SNA
1 stop19h 21m
Frontier
Sun 8/167:53 pm
SNA
- STL
1 stop20h 22m
Frontier
Deal found 7/22![Frontier logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:58 pm
STL
- SNA
1 stop14h 26m
Frontier
Sun 8/237:53 pm
SNA
- STL
2 stops21h 20m
Frontier
Deal found 7/22![Frontier logo]()
$292
This CheapOair deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:45 pm
STL
- SNA
1 stop22h 03m
Frontier
Mon 8/317:53 pm
SNA
- STL
1 stop19h 57m
Frontier
Deal found 7/18![Frontier logo]()
$324
One-way flights from St. Louis to Santa AnaSearch for one-way flight options from St. Louis to Santa Ana. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
Search for one-way flight options from St. Louis to Santa Ana. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:08 pm
STL
- SNA
1 stop16h 20m
Frontier
Deal found 7/18![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:58 pm
STL
- SNA
1 stop14h 26m
Frontier
Deal found 7/19![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:08 pm
STL
- SNA
1 stop13h 57m
Frontier
Deal found 7/18![Frontier logo]()
$135
This Frontier deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:46 pm
STL
- SNA
1 stop6h 49m
Frontier
Deal found 7/18![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:35 am
STL
- SNA
2 stops25h 37m
Frontier
Deal found 7/19![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:08 pm
STL
- SNA
2 stops20h 53m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$147
This CheapOair deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:08 pm
STL
- SNA
1 stop16h 20m
Frontier
Deal found 7/19![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:45 pm
STL
- SNA
1 stop19h 46m
Frontier
Deal found 7/22![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:10 pm
STL
- SNA
2 stops20h 53m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$184
Find flight deals from St. Louis to Santa Ana
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $256 (Expedia) |
One-way from | $121 (Kiwi.com) |
Popular in | May |
Cheapest in | October |
Average price | $545 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
Use the filters below to find and compare flights from St. Louis to Santa Ana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Tue 11/17
2:56 pm-9:55 pm
1 stop8h 59m
Santa Ana J. Wayne/Orange Cnty
Thu 11/26
1:06 pm-8:34 pm
1 stop5h 28m
$375
Quickest round-trip
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Tue 11/17
6:35 am-10:10 am
1 stop5h 35m
Santa Ana J. Wayne/Orange Cnty
Tue 12/1
8:25 am-3:20 pm
1 stop4h 55m
$375
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Tue 8/11
11:55 am-7:50 pm
2 stops9h 55m
Santa Ana J. Wayne/Orange Cnty
Sat 8/15
6:45 am-3:30 pm
2 stops6h 45m
$429
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Wed 8/12
2:50 pm-8:55 pm
2 stops8h 05m
Santa Ana J. Wayne/Orange Cnty
Sat 8/15
6:45 am-3:30 pm
2 stops6h 45m
$429
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Wed 8/19
3:04 pm-9:30 pm
1 stop8h 26m
Santa Ana J. Wayne/Orange Cnty
Wed 8/26
7:11 am-5:10 pm
1 stop7h 59m
$449
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Fri 10/16
6:00 am-11:55 am
2 stops7h 55m
Santa Ana J. Wayne/Orange Cnty
Mon 10/19
12:15 pm-11:25 pm
2 stops9h 10m
$451
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Mon 8/10
2:20 pm-9:10 pm
2 stops8h 50m
Santa Ana J. Wayne/Orange Cnty
Mon 8/17
6:45 am-5:40 pm
2 stops8h 55m
$459
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Tue 8/11
9:00 am-12:50 pm
1 stop5h 50m
Santa Ana J. Wayne/Orange Cnty
Thu 8/13
4:14 pm-11:31 pm
1 stop5h 17m
$475
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Tue 9/8
6:08 pm-9:46 am
1 stop17h 38m
Santa Ana J. Wayne/Orange Cnty
Thu 9/17
6:46 am-11:59 pm
2 stops15h 13m
$477
St. LouisSanta Ana
STL - SNA
STLSNA
Lambert-St Louis
Thu 8/13
2:20 pm-9:10 pm
2 stops8h 50m
Santa Ana J. Wayne/Orange Cnty
Sun 8/16
5:45 pm-1:10 am
1 stop5h 25m
$484
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Santa Ana
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santa Ana in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on St. Louis-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santa Ana, California flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Santa Ana
Have a flexible travel schedule? Discover the best time to fly to Santa Ana from St. Louis with our price prediction graph.
STL-SNA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Santa Ana
Prices
More
How far ahead should I book a flight from St. Louis to Santa Ana, California?
To ensure you get the cheapest price possible for a flight from St. Louis to Santa Ana, California, you should look to book at least 57 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from St. Louis to Santa Ana, California?
Currently, October is the cheapest month in which you can book a flight from St. Louis to Santa Ana, California (average of $332). Flying from St. Louis to Santa Ana, California in May is currently the most expensive (average of $790). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Santa Ana, California?
What’s the top layover airport for flights from St. Louis to Santa Ana, California?
Share of 1-stop round-trip flights from St. Louis to Santa Ana, California chosen by Cheapflights users in the past 12 months, using the same layover each way.
Phoenix (PHX) – chosen by Cheapflights users on 50% of 1-stop itineraries from St. Louis to Santa Ana, California on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to Santa Ana, California?
Average round-trip fare for 1-stop flights from St. Louis to Santa Ana, California, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Dallas (DFW) is the most affordable 1-stop option, with an average round-trip price of $341.
What’s the fastest layover option from St. Louis to Santa Ana, California?
Shortest average travel time for 1-stop one-way flights from St. Louis to Santa Ana, California, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Phoenix (PHX) have the shortest average one-way travel time for 1-stop routes: 5h 43m.
Which airport typically offers the quickest layover for flights from St. Louis to Santa Ana, California?
Average layover duration for 1-stop one-way flights from St. Louis to Santa Ana, California, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Phoenix (PHX) offer the fastest connection on this route, with an average layover time of 0h 55m.
Reviews of airlines servicing Santa Ana
Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated July 23, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from St. Louis to Santa Ana to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santa Ana?
Book flights to Santa Ana if you plan to visit one of these locationsTustin
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from St. Louis
Popular flights
Santa Ana flight routes
Alternative routes for St. Louis to Santa Ana
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santa Ana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Santa Ana by cabin class
Find flights from St. Louis to Santa Ana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Santa Ana flights
Browse other St. Louis and Santa Ana flight options. Last updated on July 23, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on July 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santa Ana
Explore flights to Santa Ana departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 23, 2026.
Top 4 airlines flying from St. Louis to Santa Ana
Discover the top 4 airlines that operate flights from St. Louis to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$159 | Average$270 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$296 | Average$455 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$332 | Average$570 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$332 | Average$513 | FlexibilityNo cancel fee | On-time69% |