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$73+ Cheap flights from Medford to Santa Ana (MFR - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — SNA
Oct 19 — Oct 261
Sun 10/19
Sun 10/26
1 adult, Economy
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Cheapflights Tip: The best prices from Medford to Santa Ana J. Wayne/Orange Cnty are usually found in March or May, booked 87 days in advance, depart on a Friday or Thursday and return on a Friday

Cheap flight deals from Medford to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 19, 2025.

Round-trip from

$140
(Cheapflightsfares)

One-way from

$73
(Cheapflightsfares)

Popular in

July

Cheapest in

March

Average price

$389

Good round-trip deal

$216 or less

Good one-way deal

$146 or less
From Medford to Santa Ana J. Wayne/Orange Cnty
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One-way flight from Medford to Santa Ana J. Wayne/Orange Cnty
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Highest demand for flights based on searches. 13% potential increase in price ($43 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Medford to Santa Ana J. Wayne/Orange Cnty.
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Price to beat on a one-way flight from Medford to Santa Ana J. Wayne/Orange Cnty.
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Find flight deals from Medford to Santa Ana

Cheapest flights from Medford to Santa Ana
Explore the most affordable flight options available from Medford to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:07 pmMFR - SNA
Nonstop2h 01mAllegiant Air
Sun 12/76:58 pmSNA - MFR
Nonstop2h 08mAllegiant Air
Deal found 9/16$140
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/204:07 pmMFR - SNA
Nonstop2h 01mAllegiant Air
Sun 11/236:58 pmSNA - MFR
Nonstop2h 03mAllegiant Air
Deal found 9/17$147
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/245:12 pmMFR - SNA
1 stop4h 51mMultiple Airlines
Sun 10/266:53 pmSNA - MFR
Nonstop1h 59mMultiple Airlines
Deal found 9/16$195
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:12 pmMFR - SNA
1 stop26h 02mMultiple Airlines
Sun 10/196:53 pmSNA - MFR
Nonstop1h 59mMultiple Airlines
Deal found 9/16$210
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/234:06 pmMFR - SNA
Nonstop1h 57mMultiple Airlines
Mon 10/276:45 amSNA - MFR
1 stop8h 46mMultiple Airlines
Deal found 9/17$220
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:12 pmMFR - SNA
1 stop4h 53mMultiple Airlines
Wed 10/88:09 pmSNA - MFR
1 stop19h 07mMultiple Airlines
Deal found 9/18$232
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:07 pmMFR - SNA
Nonstop2h 01mMultiple Airlines
Sun 12/77:15 amSNA - MFR
1 stop8h 02mMultiple Airlines
Deal found 9/16$243
This Trip.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/12:35 pmMFR - SNA
1 stop6h 55mHawaiian Airlines
Sat 11/88:00 amSNA - MFR
1 stop5h 55mHawaiian Airlines
Deal found 9/17$248
This Alaska Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2512:02 pmMFR - SNA
1 stop6h 23mAlaska Airlines
Tue 10/287:00 amSNA - MFR
1 stop4h 54mAlaska Airlines
Deal found 9/18$258

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from Medford to Santa Ana that are best for you.

Fly from

Medford

Fly to

Santa Ana

Route

Depart

Return

Price

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Thu 12/4

4:07 pm-6:08 pm

Nonstop2h 01m

Santa Ana J. Wayne/Orange Cnty

Sun 12/7

6:58 pm-9:06 pm

Nonstop2h 08m

$140

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Fri 10/17

5:12 pm-10:03 pm

1 stop4h 51m

Santa Ana J. Wayne/Orange Cnty

Sun 10/19

6:53 pm-8:52 pm

Nonstop1h 59m

$242

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Sat 11/1

2:35 pm-9:30 pm

1 stop6h 55m

Santa Ana J. Wayne/Orange Cnty

Sat 11/8

8:00 am-1:55 pm

1 stop5h 55m

$248

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Thu 10/23

3:52 pm-8:22 pm

1 stop4h 30m

Santa Ana J. Wayne/Orange Cnty

Mon 10/27

6:45 am-3:31 pm

1 stop8h 46m

$273

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Fri 10/24

3:52 pm-8:22 pm

1 stop4h 30m

Santa Ana J. Wayne/Orange Cnty

Tue 10/28

5:58 pm-12:12 am

1 stop6h 14m

$286

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Tue 11/11

1:26 pm-9:30 pm

1 stop8h 04m

Santa Ana J. Wayne/Orange Cnty

Fri 11/14

5:58 pm-12:12 am

1 stop6h 14m

$286

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Wed 1/28

3:40 pm-10:30 pm

1 stop6h 50m

Santa Ana J. Wayne/Orange Cnty

Sun 2/1

8:00 am-3:00 pm

1 stop7h 00m

$286

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Sat 10/18

2:41 pm-8:30 pm

1 stop5h 49m

Santa Ana J. Wayne/Orange Cnty

Thu 10/23

6:45 am-3:15 pm

1 stop8h 30m

$286

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Sat 10/25

6:00 am-2:15 pm

1 stop8h 15m

Santa Ana J. Wayne/Orange Cnty

Mon 10/27

7:00 pm-11:49 pm

1 stop4h 49m

$287

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Wed 10/8

12:02 pm-6:25 pm

1 stop6h 23m

Santa Ana J. Wayne/Orange Cnty

Wed 10/22

7:00 am-11:47 am

1 stop4h 47m

$292

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 22 results
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Best time to book a flight from Medford to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Santa Ana

How far ahead should I book a flight from Medford to Santa Ana?

Use this chart to determine the optimal time to book a round-trip flight from Medford to Santa Ana. Price data was last updated on September 12, 2025.

The best time to book flights from Medford to Santa Ana is 85 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Medford to Santa Ana?

Currently, January is the cheapest month in which you can book a flight from Medford to Santa Ana (average of $298). Flying from Medford to Santa Ana in March is currently the most expensive (average of $375). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFR to SNA?

Find hourly flight availability from Medford to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 19, 2025.

A simple way to save on the total cost of your ticket is to fly from Medford to Santa Ana in the afternoon. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated September 19, 2025.
See what other customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to Santa Ana have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Entertainment

7.1

Food

7.1

Overall

8.0

Comfort

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Entertainment

7.1

Food

7.1

Overall

8.0

Comfort

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Delta
8.0
Very good
7,964 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Entertainment

7.1

Food

7.1

Overall

8.0

Comfort

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
8,926 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Entertainment

7.1

Food

7.1

Overall

8.0

Comfort

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Allegiant Air
7.2
Good
699 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Entertainment

7.1

Food

7.1

Overall

8.0

Comfort

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Medford to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Medford to Santa Ana flight route?

    The Medford to Santa Ana J. Wayne/Orange Cnty flight path was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Medford to Santa Ana?

    Airlines like Allegiant Air and Hawaiian Airlines fly from Medford to Santa Ana in about 2h 01m. The time it takes to get you to your destination can typically vary by up to 4h 54m. Airlines will cover a distance of 659 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Medford to Santa Ana round-trip?

    Our cheapest airline available from Medford to Santa Ana is Allegiant Air. Our recent data shows that you can find tickets from as low as $94 on this airline. Additional options worth looking into are Delta and Alaska Airlines, starting at $183 and $257 round-trip. Users have found that Allegiant Air is 65% cheaper than the other options available to this destination.

  • What are the cheapest flights from Medford to Santa Ana?

    Looking at all options, your cheapest flight can be booked for $146. While the most popular route (Medford - Santa Ana J. Wayne/Orange Cnty) can be booked for $147 on average, our data indicates $235 when flying from Medford to Santa Ana.

  • Can I find deals for flights from Medford to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Medford to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Santa Ana.

  • Can I find deals for business class flights from Medford to Santa Ana?

    Yes. Cheapflights offers flight deals from Medford to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Santa Ana?

    Currently, January is the cheapest month in which you can book a flight from Medford to Santa Ana (average of $298). Flying from Medford to Santa Ana in March is currently the most expensive (average of $375). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

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Alternative routes for Medford to Santa Ana

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Top 4 airlines flying from Medford to Santa Ana

Discover the top 4 airlines that operate flights from Medford to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$94Average$185FlexibilityNo cancel feeOn-time88%
DeltaCheapest$183Average$373FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$257Average$360FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$263Average$371FlexibilityNo cancel feeOn-time69%

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