How long is the flight from Florence, South Carolina to Santa Ana, California?

A quick flight from Florence, South Carolina to Santa Ana, California can take about 11h 57m. American Airlines provides one of the quickest options available for as low as $559. The distance between Florence, South Carolina and Santa Ana, California is about 2172 mi.

In terms of precipitation, rainfall in Santa Ana, California ranges from 0.0 - 3.1 inches per month. February is typically the wettest month, when rainfall can reach 3.1 in. July is typically the driest time to visit Santa Ana, California when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santa Ana, California, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What is the cheapest time of day to fly from FLO to SNA?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florence, South Carolina to Santa Ana, California as you normally would.

Most accurate provider : When it comes to deals on Florence, South Carolina-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Santa Ana, California flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Florence, South Carolina-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Florence to Santa Ana that include hotel bookings?

Yes. In addition to deals on Florence to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Florence to Santa Ana?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Santa Ana.

Can I find deals for business class flights from Florence to Santa Ana?

Yes. Cheapflights offers flight deals from Florence to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$466+ Flights from Florence, SC to Santa Ana, CA

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Cheap flight deals from Florence to Santa Ana

Cheapest flights from Florence to Santa Ana
Explore the most affordable flight options available from Florence to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Wed 12/316:30 pmFLO - SNA

2 stops17h 30mAmerican Airlines

Sun 1/49:59 amSNA - FLO

2 stops11h 16mAmerican Airlines

Deal found 12/16

$675

Best flights from Florence to Santa Ana
Discover carefully curated flight deals from Florence to Santa Ana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Thu 1/112:51 pmFLO - SNA

2 stops11h 57mAmerican Airlines

Mon 1/57:45 amSNA - FLO

1 stop7h 20mAmerican Airlines

Deal found 12/17

$559

Wed 12/316:30 pmFLO - SNA

2 stops17h 30mAmerican Airlines

Sun 1/49:59 amSNA - FLO

2 stops11h 16mAmerican Airlines

Deal found 12/16

$675

Last-minute flights from Florence to Santa Ana
Discover last-minute flight deals from Florence to Santa Ana. Data last updated December 18, 2025 and is based on user searches.

Wed 12/316:30 pmFLO - SNA

2 stops17h 30mAmerican Airlines

Sun 1/49:59 amSNA - FLO

2 stops11h 16mAmerican Airlines

Deal found 12/16

$675

Thu 1/112:51 pmFLO - SNA

2 stops11h 57mAmerican Airlines

Mon 1/57:45 amSNA - FLO

1 stop7h 20mAmerican Airlines

Deal found 12/17

$559

One-way flights from Florence to Santa Ana
Search for one-way flight options from Florence to Santa Ana. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Sun 2/159:30 amFLO - SNA

2 stops15h 02mAmerican Airlines

Deal found 12/16

$466

Find flight deals from Florence to Santa Ana

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 1 star
Round-trip from	$559 (American Airlines)
One-way from	$466 (American Airlines)

Provider with most accurate pricing for Florence-Santa Ana J. Wayne/Orange Cnty flight deals.

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Provider most trusted by Cheapflights users for Florence-Santa Ana J. Wayne/Orange Cnty flights.

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From Florence to Santa Ana J. Wayne/Orange Cnty

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One-way flight from Florence to Santa Ana J. Wayne/Orange Cnty

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Florence to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

FlorenceSanta Ana

FLO - SNA

FLOSNA

Florence

Thu 1/1

12:51 pm-9:48 pm

2 stops11h 57m

Santa Ana J. Wayne/Orange Cnty

Mon 1/5

7:45 am-6:05 pm

1 stop7h 20m

$559

FlorenceSanta Ana

FLO - SNA

FLOSNA

Florence

Wed 12/31

6:30 pm-9:00 am

2 stops17h 30m

Santa Ana J. Wayne/Orange Cnty

Sun 1/4

9:59 am-12:15 am

2 stops11h 16m

$675

FlorenceSanta Ana

FLO - SNA

FLOSNA

Florence

Sun 2/15

9:30 am-9:32 pm

2 stops15h 02m

$466

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Most accurate provider: When it comes to deals on Florence, South Carolina-Santa Ana, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Santa Ana, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Santa Ana, California flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Florence, South Carolina-Santa Ana, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Florence to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Florence with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Santa Ana

What is the cheapest month to book a flight from Florence, South Carolina to Santa Ana, California?

Currently, May is the cheapest month in which you can book a flight from Florence, South Carolina to Santa Ana, California (average of $91). Flying from Florence, South Carolina to Santa Ana, California in November is currently the most expensive (average of $201). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

How long is the flight from Florence, South Carolina to Santa Ana, California?
A quick flight from Florence, South Carolina to Santa Ana, California can take about 11h 57m. American Airlines provides one of the quickest options available for as low as $559. The distance between Florence, South Carolina and Santa Ana, California is about 2172 mi.
Can I find deals for flights from Florence to Santa Ana that include hotel bookings?
Yes. In addition to deals on Florence to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Florence to Santa Ana?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Santa Ana.
Can I find deals for business class flights from Florence to Santa Ana?
Yes. Cheapflights offers flight deals from Florence to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Florence, South Carolina to Santa Ana, California?
Currently, May is the cheapest month in which you can book a flight from Florence, South Carolina to Santa Ana, California (average of $91). Flying from Florence, South Carolina to Santa Ana, California in November is currently the most expensive (average of $201). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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$466+ Cheap flights from Florence, SC to Santa Ana, CA (FLO - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Florence to Santa Ana with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Florence to Santa Ana

Cheapest flights from Florence to Santa AnaExplore the most affordable flight options available from Florence to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Florence to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Florence to Santa Ana

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florence to Santa Ana that are best for you.

Best time to book a flight from Florence to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Florence with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Florence to Santa Ana

What is the cheapest month to book a flight from Florence, South Carolina to Santa Ana, California?

Related info for your journey

Find useful and relevant information for your journey from Florence to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Florence, South Carolina to Santa Ana, California?

Can I find deals for flights from Florence to Santa Ana that include hotel bookings?

How can I find direct flights from Florence to Santa Ana?

Can I find deals for business class flights from Florence to Santa Ana?

What is the cheapest month to book a flight from Florence, South Carolina to Santa Ana, California?

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Cheapest flights from Florence to Santa Ana
Explore the most affordable flight options available from Florence to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.