$156+ Cheap flights from Des Moines to San Jose, CA (DSM - SJC)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJC
Apr 12 — Apr 191
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Des Moines to San Jose with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to San Jose
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to San JoseExplore the most affordable flight options available from Des Moines to San Jose. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
Explore the most affordable flight options available from Des Moines to San Jose. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:55 am
DSM
- SJC
1 stop5h 40m
Southwest
Sat 4/181:15 pm
SJC
- DSM
1 stop5h 40m
Southwest
Deal found 3/10![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:30 pm
DSM
- SJC
1 stop5h 25m
Southwest
Wed 4/2911:15 am
SJC
- DSM
2 stops8h 00m
Southwest
Deal found 3/9![Southwest logo]()
$342
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:55 am
DSM
- SJC
1 stop5h 40m
Southwest
Tue 4/147:45 am
SJC
- DSM
1 stop8h 10m
Southwest
Deal found 3/10![Southwest logo]()
$352
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:40 am
DSM
- SJC
1 stop5h 40m
Southwest
Sat 5/26:30 am
SJC
- DSM
1 stop5h 00m
Southwest
Deal found 3/11![Southwest logo]()
$357
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:33 pm
DSM
- SJC
2 stops11h 08m
Delta
Tue 5/2610:55 pm
SJC
- DSM
1 stop8h 51m
Delta
Deal found 3/10![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:19 am
DSM
- SJC
1 stop8h 47m
American Airlines
Tue 5/264:25 pm
SJC
- DSM
1 stop5h 21m
American Airlines
Deal found 3/11![American Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am
DSM
- SJC
1 stop7h 09m
Delta
Wed 12/210:20 pm
SJC
- DSM
1 stop9h 58m
Delta
Deal found 3/9![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/22:33 pm
DSM
- SJC
1 stop10h 22m
Delta
Wed 6/106:10 pm
SJC
- DSM
2 stops14h 05m
Delta
Deal found 3/8![Delta logo]()
$388
Best flights from Des Moines to San JoseDiscover carefully curated flight deals from Des Moines to San Jose that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
Discover carefully curated flight deals from Des Moines to San Jose that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:15 pm
DSM
- SJC
2 stops8h 55m
Southwest
Wed 4/2911:15 am
SJC
- DSM
2 stops8h 00m
Southwest
Deal found 3/9![Southwest logo]()
$357
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:33 pm
DSM
- SJC
2 stops11h 08m
Delta
Tue 5/266:15 am
SJC
- DSM
2 stops12h 21m
Delta
Deal found 3/10![Delta logo]()
$383
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:40 am
DSM
- SJC
1 stop5h 40m
Southwest
Sat 5/21:15 pm
SJC
- DSM
1 stop5h 40m
Southwest
Deal found 3/11![Southwest logo]()
$357
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/162:15 pm
DSM
- SJC
1 stop10h 38m
Delta
Fri 8/710:56 pm
SJC
- DSM
1 stop8h 23m
Delta
Deal found 3/8![Delta logo]()
$417
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:33 pm
DSM
- SJC
1 stop10h 22m
Delta
Sun 5/246:15 am
SJC
- DSM
1 stop7h 19m
Delta
Deal found 3/8![Delta logo]()
$447
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:10 pm
DSM
- SJC
1 stop9h 30m
Southwest
Sun 6/76:15 am
SJC
- DSM
1 stop7h 20m
Southwest
Deal found 3/9![Southwest logo]()
$452
Last-minute flights from Des Moines to San JoseDiscover last-minute flight deals from Des Moines to San Jose. Data last updated March 13, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to San Jose. Data last updated March 13, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:55 am
DSM
- SJC
1 stop5h 40m
Southwest
Tue 4/147:45 am
SJC
- DSM
1 stop8h 10m
Southwest
Deal found 3/10![Southwest logo]()
$352
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:55 am
DSM
- SJC
1 stop5h 40m
Southwest
Sat 4/181:15 pm
SJC
- DSM
1 stop5h 40m
Southwest
Deal found 3/10![Southwest logo]()
$337
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:44 pm
DSM
- SJC
2 stops10h 58m
Delta
Sat 4/189:37 am
SJC
- DSM
2 stops9h 35m
Delta
Deal found 3/10![Delta logo]()
$409
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:30 pm
DSM
- SJC
1 stop5h 25m
Southwest
Wed 4/2911:15 am
SJC
- DSM
2 stops8h 00m
Southwest
Deal found 3/9![Southwest logo]()
$342
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:10 pm
DSM
- SJC
1 stop5h 15m
Southwest
Thu 4/3010:55 pm
SJC
- DSM
1 stop10h 50m
Southwest
Deal found 3/9![Southwest logo]()
$394
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/243:21 pm
DSM
- SJC
1 stop9h 20m
United Airlines
Wed 5/1312:56 pm
SJC
- DSM
1 stop7h 49m
United Airlines
Deal found 3/12![United Airlines logo]()
$412
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:10 pm
DSM
- SJC
1 stop5h 15m
Southwest
Wed 5/1311:25 am
SJC
- DSM
2 stops7h 50m
Southwest
Deal found 3/12![Southwest logo]()
$417
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:40 am
DSM
- SJC
1 stop5h 40m
Southwest
Sat 5/26:30 am
SJC
- DSM
1 stop5h 00m
Southwest
Deal found 3/11![Southwest logo]()
$357
One-way flights from Des Moines to San JoseSearch for one-way flight options from Des Moines to San Jose. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
Search for one-way flight options from Des Moines to San Jose. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3110:26 pm
DSM
- SJC
1 stop16h 48m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:56 pm
DSM
- SJC
1 stop21h 06m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$161
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:00 am
DSM
- SJC
1 stop7h 10m
American Airlines
Deal found 3/10![American Airlines logo]()
$169
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:15 pm
DSM
- SJC
2 stops8h 55m
Southwest
Deal found 3/10![Southwest logo]()
$174
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:17 pm
DSM
- SJC
1 stop6h 15m
United Airlines
Deal found 3/11![United Airlines logo]()
$179
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:56 am
DSM
- SJC
2 stops10h 11m
Delta
Deal found 3/10![Delta logo]()
$184
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:01 am
DSM
- SJC
2 stops10h 26m
Delta
Deal found 3/10![Delta logo]()
$189
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1612:05 pm
DSM
- SJC
2 stops8h 00m
Southwest
Deal found 3/11![Southwest logo]()
$200
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:35 am
DSM
- SJC
1 stop8h 33m
Delta
Deal found 3/10![Delta logo]()
$205
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:00 am
DSM
- SJC
1 stop7h 07m
American Airlines
Deal found 3/11![American Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:11 pm
DSM
- SJC
2 stops38h 50m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$218
Find flight deals from Des Moines to San Jose
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to San Jose (SJC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $337 (Southwest) |
One-way from | $156 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $688 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to San Jose that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Des Moines to San Jose that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan Jose
DSM - SJC
DSMSJC
Des Moines
Wed 4/22
3:15 pm-10:10 pm
2 stops8h 55m
San Jose
Wed 4/29
11:15 am-9:15 pm
2 stops8h 00m
$357
Quickest round-trip
Des MoinesSan Jose
DSM - SJC
DSMSJC
Des Moines
Sat 4/25
6:40 am-10:20 am
1 stop5h 40m
San Jose
Sat 5/2
1:15 pm-8:55 pm
1 stop5h 40m
$357
Des MoinesSan Jose
DSM - SJC
DSMSJC
Des Moines
Wed 5/20
2:33 pm-11:41 pm
2 stops11h 08m
San Jose
Tue 5/26
6:15 am-8:36 pm
2 stops12h 21m
$383
Des MoinesSan Jose
DSM - SJC
DSMSJC
Des Moines
Tue 6/16
2:15 pm-10:53 pm
1 stop10h 38m
San Jose
Fri 8/7
10:56 pm-9:19 am
1 stop8h 23m
$417
Des MoinesSan Jose
DSM - SJC
DSMSJC
Des Moines
Fri 5/22
2:33 pm-10:55 pm
1 stop10h 22m
San Jose
Sun 5/24
6:15 am-3:34 pm
1 stop7h 19m
$447
Des MoinesSan Jose
DSM - SJC
DSMSJC
Des Moines
Sat 5/30
2:10 pm-9:40 pm
1 stop9h 30m
San Jose
Sun 6/7
6:15 am-3:35 pm
1 stop7h 20m
$452
Cheapest one-way
Des MoinesSan Jose
DSM - SJC
DSMSJC
Des Moines
Mon 6/15
9:56 pm-5:02 pm
1 stop21h 06m
$161
Des MoinesSan Jose
DSM - SJC
DSMSJC
Des Moines
Tue 5/5
10:34 am-8:37 pm
2 stops12h 03m
$184
Des MoinesSan Jose
DSM - SJC
DSMSJC
Des Moines
Tue 6/2
7:01 am-3:27 pm
2 stops10h 26m
$189
Des MoinesSan Jose
DSM - SJC
DSMSJC
Des Moines
Thu 4/9
5:35 am-12:08 pm
1 stop8h 33m
$205
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Des Moines to San Jose
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to San Jose in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-San Jose, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-San Jose, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-San Jose, California flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-San Jose, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-San Jose, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to San Jose
Have a flexible travel schedule? Discover the best time to fly to San Jose from Des Moines with our price prediction graph.
DSM-SJC
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to San Jose
Reviews of airlines servicing San Jose
Get insights into the airlines that provide service to San Jose. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Jose. Reviews last updated March 13, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Des Moines to San Jose by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Related info for your journey
Find useful and relevant information for your journey from Des Moines to San Jose. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Des Moines
Popular flights
San Jose flight routes
Alternative routes for Des Moines to San Jose
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Jose by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to San Jose by cabin class
Find flights from Des Moines to San Jose, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and San Jose flights
Browse other Des Moines and San Jose flight options. Last updated on March 13, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on March 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Jose
Explore flights to San Jose departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 13, 2026.
Top 4 airlines flying from Des Moines to San Jose
Discover the top 4 airlines that operate flights from Des Moines to San Jose. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$179 | Average$347 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$290 | Average$732 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$467 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$356 | Average$467 | FlexibilityNo cancel fee | On-time63% |