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$90+ Cheap flights from South Carolina to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SFO
feb. 26 — mar. 51
jue. 2/26
jue. 3/5
1 adult, Economy
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Cheap flight deals from South Carolina to San Francisco

Cheapest flights from South Carolina to San Francisco
Explore the most affordable flight options available from South Carolina to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 27, 2026.

This Breeze Airways deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/266:30 am
CHS
-
SFO
1 stop8h 07m
Breeze Airways
mar. 9/112:47 pm
SFO
-
CHS
1 stop7h 00m
Breeze Airways
Deal found 1/27$209
This Breeze Airways deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/266:30 am
CHS
-
SFO
1 stop8h 07m
Breeze Airways
mié. 9/912:22 pm
SFO
-
CHS
1 stop7h 27m
Breeze Airways
Deal found 1/26$223
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/67:25 am
CHS
-
SFO
1 stop7h 37m
Breeze Airways
dom. 9/1312:47 pm
SFO
-
CHS
1 stop7h 00m
Breeze Airways
Deal found 1/26$229
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/175:10 pm
CHS
-
SFO
1 stop8h 48m
United Airlines
sáb. 2/2110:50 pm
SFO
-
CHS
1 stop8h 19m
United Airlines
Deal found 1/27$251
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/241:25 pm
CHS
-
SFO
1 stop9h 49m
American Airlines
vie. 2/2711:30 pm
SFO
-
CHS
1 stop9h 07m
American Airlines
Deal found 1/27$257
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/183:54 pm
CHS
-
SFO
2 stops10h 20m
American Airlines
lun. 2/237:00 am
SFO
-
CHS
1 stop8h 22m
American Airlines
Deal found 1/25$262
This United Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/77:40 pm
CHS
-
SFO
1 stop8h 36m
United Airlines
lun. 8/109:30 pm
SFO
-
CHS
1 stop9h 25m
United Airlines
Deal found 1/24$263
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/245:27 am
CHS
-
SFO
2 stops11h 21m
Delta
mar. 3/32:05 pm
SFO
-
CHS
1 stop6h 49m
Delta
Deal found 1/26$275
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/245:27 am
CHS
-
SFO
2 stops11h 21m
Delta
vie. 2/279:30 pm
SFO
-
CHS
1 stop8h 53m
Delta
Deal found 1/27$278
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 4/185:02 am
CHS
-
SFO
1 stop10h 14m
American Airlines
sáb. 4/2511:50 am
SFO
-
CHS
1 stop8h 03m
American Airlines
Deal found 1/26$288
This CheapOair deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/48:08 pm
CHS
-
SFO
1 stop18h 01m
JetBlue
sáb. 5/97:00 am
SFO
-
CHS
1 stop9h 05m
JetBlue
Deal found 1/25$295
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/167:00 am
CHS
-
SFO
1 stop8h 15m
United Airlines
mar. 6/169:30 pm
SFO
-
CHS
1 stop9h 31m
United Airlines
Deal found 1/26$300

Find flight deals from South Carolina to San Francisco

Keep the following information in mind while searching for South Carolina to San Francisco flight deals. Data was last updated enero 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$251
(United Airlines)

One-way from

$90
(Frontier)

Popular in

November

Cheapest in

April

Average price

$428
Provider with most accurate pricing for Myrtle Beach Intl-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Francisco flights.
Search Deals
From South Carolina to San Francisco
Search Deals
One-way flight from South Carolina to San Francisco
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($90 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 27, 2026.
Use the filters below to find and compare flights from South Carolina to San Francisco that are best for you.

Fly from

South Carolina

Fly to

San Francisco

Route

Depart

Return

Price

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

mar. 2/24

10:20 am-3:51 pm

1 stop8h 31m

San Francisco

mar. 3/3

10:40 pm-10:09 am

1 stop8h 29m

$251

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

lun. 4/6

7:58 pm-12:35 am

1 stop7h 37m

San Francisco

mar. 4/14

10:35 pm-8:51 am

1 stop7h 16m

$263

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

jue. 2/19

7:47 pm-1:28 am

1 stop8h 41m

San Francisco

dom. 2/22

11:20 pm-10:09 am

1 stop7h 49m

$263

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

mar. 3/10

8:00 am-1:33 pm

1 stop8h 33m

San Francisco

lun. 3/16

9:30 pm-10:04 am

1 stop9h 34m

$263

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

jue. 4/23

7:44 pm-1:17 am

1 stop8h 33m

San Francisco

lun. 4/27

11:52 pm-12:25 pm

1 stop9h 33m

$263

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

mar. 2/24

5:27 am-1:48 pm

2 stops11h 21m

San Francisco

vie. 2/27

10:50 pm-9:23 am

1 stop7h 33m

$278

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

mar. 3/10

5:27 am-2:04 pm

2 stops11h 37m

San Francisco

lun. 3/16

10:40 pm-10:37 am

1 stop8h 57m

$278

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

mié. 4/1

4:51 pm-11:19 pm

1 stop9h 28m

San Francisco

mar. 4/14

10:32 am-11:50 pm

2 stops10h 18m

$308

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

mar. 2/24

5:27 am-1:48 pm

2 stops11h 21m

San Francisco

mar. 3/3

7:00 pm-9:23 am

2 stops11h 23m

$309

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

mié. 2/11

6:00 am-7:36 pm

1 stop16h 36m

San Francisco

mié. 3/4

10:00 pm-9:23 am

1 stop8h 23m

$320

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to San Francisco

What is the cheapest month to book a flight from South Carolina to San Francisco?

Currently, November is the cheapest month in which you can book a flight from South Carolina to San Francisco (average of $160). Flying from South Carolina to San Francisco in March is currently the most expensive (average of $276). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SFO?

Find hourly flight availability from South Carolina to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 27, 2026.

A simple way to save on the total cost of your ticket is to fly from South Carolina to San Francisco in the afternoon. If you’re flexible enough to do this you can expect to save up to 48% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from South Carolina to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to San Francisco. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their South Carolina to San Francisco flight should consider departing on Tuesday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from South Carolina to San Francisco?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from South Carolina?

    Most people fly into San Francisco (SFO) if they book a flight to San Francisco from South Carolina. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

  • How long is the flight from South Carolina to San Francisco?

    United Airlines, Delta, and Southwest can get you from South Carolina to San Francisco in just under 7h 59m. Your travel time can differ by up to 4h 41m. The distance between South Carolina and San Francisco is about 2306 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to San Francisco one-way?

    One-way options have recently been found by users for as low as $76 on Viva. Other airlines that offer cheap prices include Volaris from $117 and Aeromexico from $124 one-way.

  • What are the most popular routes from South Carolina to San Francisco?

    The most popular route from South Carolina to San Francisco is Charlotte Douglas - San Francisco. You may also consider Charleston - San Francisco or Columbia Metropolitan - San Francisco.

  • Can I find deals for flights from South Carolina to San Francisco that include hotel bookings?

    Yes. In addition to deals on South Carolina to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to San Francisco.

  • Can I find deals for business class flights from South Carolina to San Francisco?

    Yes. Cheapflights offers flight deals from South Carolina to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to San Francisco?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to San Francisco (average of $160). Flying from South Carolina to San Francisco in March is currently the most expensive (average of $276). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Roseville
Santa Clara
Livermore
Watsonville
San Bruno
Daly City
Sunnyvale
Turlock
Vacaville
San Carlos
San Ramon
Manteca
Vallejo
San Lorenzo
Davis
Hollister
Redwood City
Union City

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to San Francisco

Discover the top 5 airlines that operate flights from South Carolina to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$118Average$282FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$155Average$440FlexibilityNo cancel feeOn-time63%
DeltaCheapest$199Average$423FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$246Average$425FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$263Average$436FlexibilityNo cancel feeOn-time69%

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