San Francisco

$101+ Cheap flights from South Carolina to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SFO
May 6 — May 131
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Cheap flight deals from South Carolina to San Francisco

Keep the following information in mind while searching for South Carolina to San Francisco flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$188
(CheapOair)

One-way from

$101
(CheapOair)

Popular in

July

Cheapest in

April

Average price

$388
Provider with most accurate pricing for Myrtle Beach Intl-San Francisco flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Francisco flights.
From South Carolina to San Francisco
One-way flight from South Carolina to San Francisco
Highest demand for flights based on searches. 12% potential increase in price ($65 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Average for round-trip flights in May 2025

Find flight deals from South Carolina to San Francisco

Cheapest flights from South Carolina to San Francisco
Explore the most affordable flight options available from South Carolina to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/106:25 amCHS - SFO
1 stop8h 14mBreeze Airways
Wed 5/1412:24 pmSFO - CHS
1 stop7h 22mBreeze Airways
Deal found 4/30$188
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/12:26 pmCHS - SFO
1 stop10h 01mAmerican Airlines
Sat 7/55:41 amSFO - CHS
1 stop9h 36mAmerican Airlines
Deal found 4/30$217
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/154:05 pmCHS - SFO
1 stop8h 00mUnited Airlines
Sun 5/1812:10 amSFO - CHS
1 stop7h 21mUnited Airlines
Deal found 4/30$229
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2911:09 amSAV - SFO
1 stop10h 25mAmerican Airlines
Mon 6/212:21 amSFO - SAV
1 stop7h 12mAmerican Airlines
Deal found 4/28$235
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:30 amCHS - SFO
1 stop10h 34mDelta
Mon 9/2212:40 amSFO - CHS
1 stop10h 28mDelta
Deal found 4/30$277
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2911:05 amSAV - SFO
1 stop10h 34mDelta
Sat 8/3012:40 amSFO - SAV
1 stop10h 23mDelta
Deal found 4/29$278
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/114:45 pmSAV - SFO
1 stop8h 53mUnited Airlines
Mon 7/1411:20 pmSFO - SAV
1 stop8h 44mUnited Airlines
Deal found 4/29$279
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/287:10 amCAE - SFO
1 stop8h 24mAmerican Airlines
Wed 6/48:58 amSFO - CAE
1 stop9h 56mAmerican Airlines
Deal found 4/30$279
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:35 amCHS - SFO
2 stops11h 05mSouthwest
Tue 9/2310:50 amSFO - CHS
1 stop7h 25mSouthwest
Deal found 4/30$284
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/307:49 pmCAE - SFO
1 stop8h 09mUnited Airlines
Sat 6/75:05 amSFO - CAE
1 stop8h 55mUnited Airlines
Deal found 4/30$294
This Alaska Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:45 pmCHS - SFO
1 stop16h 33mAlaska Airlines
Mon 10/139:40 pmSFO - CHS
1 stop16h 51mAlaska Airlines
Deal found 4/30$312
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/295:27 pmCLT - SFO
1 stop9h 42mFrontier
Sun 7/138:53 pmSFO - CLT
1 stop10h 36mFrontier
Deal found 4/29$313

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from South Carolina to San Francisco that are best for you.

Fly from

South Carolina

Fly to

San Francisco

Route

Depart

Return

Price

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Sun 9/14

7:05 am-12:05 pm

1 stop8h 00m

San Francisco

Thu 9/18

12:50 pm-10:43 pm

1 stop6h 53m

$188

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Tue 7/1

2:26 pm-9:27 pm

1 stop10h 01m

San Francisco

Sat 7/5

5:41 am-6:17 pm

1 stop9h 36m

$217

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Thu 5/15

7:00 am-12:20 pm

1 stop8h 20m

San Francisco

Mon 5/19

5:00 am-4:25 pm

1 stop8h 25m

$229

SavannahSan Francisco

SAV - SFO

SAVSFO

Savannah/Hilton Head

Thu 5/29

1:26 pm-8:55 pm

1 stop10h 29m

San Francisco

Tue 6/3

8:58 am-9:55 pm

1 stop9h 57m

$235

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Tue 9/16

6:30 am-2:04 pm

1 stop10h 34m

San Francisco

Mon 9/22

12:40 am-2:08 pm

1 stop10h 28m

$277

SavannahSan Francisco

SAV - SFO

SAVSFO

Savannah/Hilton Head

Thu 6/5

4:51 pm-11:32 pm

1 stop9h 41m

San Francisco

Mon 6/9

11:59 pm-10:54 am

1 stop7h 55m

$279

ColumbiaSan Francisco

CAE - SFO

CAESFO

Columbia Metropolitan

Wed 5/28

7:10 am-12:34 pm

1 stop8h 24m

San Francisco

Wed 6/4

8:58 am-9:54 pm

1 stop9h 56m

$279

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Tue 9/16

6:35 am-2:40 pm

2 stops11h 05m

San Francisco

Tue 9/23

10:50 am-9:15 pm

1 stop7h 25m

$284

ColumbiaSan Francisco

CAE - SFO

CAESFO

Columbia Metropolitan

Fri 5/30

7:49 pm-12:58 am

1 stop8h 09m

San Francisco

Sat 6/7

5:05 am-5:00 pm

1 stop8h 55m

$294

SavannahSan Francisco

SAV - SFO

SAVSFO

Savannah/Hilton Head

Mon 6/2

4:23 pm-11:30 pm

1 stop10h 07m

San Francisco

Thu 6/5

5:05 am-3:18 pm

1 stop7h 13m

$301

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to San Francisco

What is the cheapest month to book a flight from South Carolina to San Francisco?

Currently, January is the cheapest month in which you can book a flight from South Carolina to San Francisco (average of $276). Flying from South Carolina to San Francisco in June is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SFO?

Find hourly flight availability from South Carolina to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

When flying from South Carolina to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated May 1, 2025.
Read through reviews of airlines operating flights from South Carolina to San Francisco, such as Breeze Airways, Alaska Airlines and Southwest. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

8.2

Crew

8.8

Entertainment

6.6

Food

6.7

Boarding

8.3

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Comfort

8.2

Crew

8.8

Entertainment

6.6

Food

6.7

Boarding

8.3

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Comfort

8.2

Crew

8.8

Entertainment

6.6

Food

6.7

Boarding

8.3

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Comfort

8.2

Crew

8.8

Entertainment

6.6

Food

6.7

Boarding

8.3

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
8.0
Very good

Comfort

8.2

Crew

8.8

Entertainment

6.6

Food

6.7

Boarding

8.3

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Comfort

8.2

Crew

8.8

Entertainment

6.6

Food

6.7

Boarding

8.3

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Francisco from South Carolina?

    Most people fly into San Francisco (SFO) if they book a flight to San Francisco from South Carolina. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

  • What are the cheapest airlines to fly from South Carolina to San Francisco one-way?

    One-way options have recently been found by users for as low as $101 on Breeze Airways. Other airlines that offer cheap prices include American Airlines from $109 and United Airlines from $126 one-way.

  • What are the most popular routes from South Carolina to San Francisco?

  • Can I find deals for flights from South Carolina to San Francisco that include hotel bookings?

    Yes. In addition to deals on South Carolina to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to San Francisco.

  • Can I find deals for business class flights from South Carolina to San Francisco?

    Yes. Cheapflights offers flight deals from South Carolina to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to San Francisco (average of $276). Flying from South Carolina to San Francisco in June is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
Livermore
South San Francisco
Turlock
Manteca
Fairfield
Richmond
Watsonville
Hollister
Newark
Milpitas
Antioch
Sausalito
Hayward
Alameda
Sunnyvale
Campbell
Daly City

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from South Carolina to San Francisco

Discover the top 5 airlines that operate flights from South Carolina to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$182Average$316FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$222Average$465FlexibilityNo cancel feeOn-time71%
DeltaCheapest$250Average$438FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$256Average$457FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$307Average$437FlexibilityNo cancel feeOn-time63%

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