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$63+ Cheap flights from South Carolina to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SFO
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
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Find flight deals from South Carolina to San Francisco

Cheapest flights from South Carolina to San Francisco
Explore the most affordable flight options available from South Carolina to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:25 amCHS - SFO
1 stop8h 29mBreeze Airways
Sun 12/1412:50 pmSFO - CHS
1 stop6h 53mBreeze Airways
Deal found 11/4$163
This Breeze Airways deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:05 amCHS - SFO
1 stop8h 00mBreeze Airways
Thu 12/1112:50 pmSFO - CHS
1 stop6h 53mBreeze Airways
Deal found 11/2$174
This Breeze Airways deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:25 amCHS - SFO
1 stop8h 29mBreeze Airways
Mon 12/812:47 pmSFO - CHS
1 stop6h 41mBreeze Airways
Deal found 11/3$178
This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:05 amCHS - SFO
1 stop8h 00mBreeze Airways
Tue 12/912:50 pmSFO - CHS
1 stop6h 53mBreeze Airways
Deal found 11/4$193
This Breeze Airways deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:05 amCHS - SFO
1 stop7h 57mBreeze Airways
Mon 12/1512:47 pmSFO - CHS
1 stop6h 41mBreeze Airways
Deal found 11/3$194
This Breeze Airways deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:05 amCHS - SFO
1 stop8h 00mBreeze Airways
Fri 12/512:47 pmSFO - CHS
1 stop6h 41mBreeze Airways
Deal found 11/3$195
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:25 amCHS - SFO
1 stop8h 29mMultiple Airlines
Sun 12/1411:33 pmSFO - CHS
2 stops30h 04mMultiple Airlines
Deal found 11/3$199
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:59 pmCHS - SFO
2 stops19h 54mMultiple Airlines
Fri 12/512:47 pmSFO - CHS
1 stop6h 41mMultiple Airlines
Deal found 11/3$203
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:44 pmCLT - SFO
1 stop9h 40mFrontier
Mon 12/86:30 amSFO - CLT
2 stops29h 17mFrontier
Deal found 11/2$212
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:44 pmCLT - SFO
1 stop9h 40mFrontier
Mon 12/156:30 amSFO - CLT
2 stops29h 17mFrontier
Deal found 11/3$214
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:25 amCHS - SFO
1 stop8h 29mMultiple Airlines
Mon 12/88:48 amSFO - CHS
2 stops20h 49mMultiple Airlines
Deal found 11/3$232
This Booking.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:44 pmCLT - SFO
1 stop9h 40mFrontier
Wed 12/176:30 amSFO - CLT
1 stop25h 52mFrontier
Deal found 11/2$236

Cheap flight deals from South Carolina to San Francisco

Keep the following information in mind while searching for South Carolina to San Francisco flight deals. Data was last updated November 5, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$163
(Breeze Airways)

One-way from

$63
(Kiwi.com)

Popular in

February

Cheapest in

April

Average price

$544
Provider with most accurate pricing for Myrtle Beach Intl-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Francisco flights.
Search Deals
From South Carolina to San Francisco
Search Deals
One-way flight from South Carolina to San Francisco
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($102 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from South Carolina to San Francisco that are best for you.

Fly from

South Carolina

Fly to

San Francisco

Route

Depart

Return

Price

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Fri 12/12

7:05 am-12:02 pm

1 stop7h 57m

San Francisco

Mon 12/15

12:47 pm-10:28 pm

1 stop6h 41m

$194

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Sat 1/24

1:12 pm-5:43 pm

1 stop7h 31m

San Francisco

Fri 1/30

12:47 am-2:15 pm

1 stop10h 28m

$257

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Mon 12/15

7:05 am-12:02 pm

1 stop7h 57m

San Francisco

Thu 12/18

1:29 pm-1:10 pm

2 stops20h 41m

$279

SavannahSan Francisco

SAV - SFO

SAVSFO

Savannah/Hilton Head

Sat 1/10

3:40 pm-11:59 pm

1 stop11h 19m

San Francisco

Sat 1/24

8:30 pm-12:09 pm

1 stop12h 39m

$287

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Fri 12/12

3:21 pm-8:56 pm

1 stop8h 35m

San Francisco

Mon 12/15

11:59 pm-11:39 am

2 stops8h 40m

$288

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Sat 11/8

6:25 am-11:54 am

1 stop8h 29m

San Francisco

Sat 11/15

12:39 pm-10:59 pm

1 stop7h 20m

$301

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Wed 11/12

6:25 am-11:54 am

1 stop8h 29m

San Francisco

Sat 11/15

12:39 pm-10:59 pm

1 stop7h 20m

$301

ColumbiaSan Francisco

CAE - SFO

CAESFO

Columbia Metropolitan

Fri 1/30

8:00 am-2:07 pm

1 stop9h 07m

San Francisco

Sun 2/1

11:55 pm-2:14 pm

1 stop11h 19m

$309

ColumbiaSan Francisco

CAE - SFO

CAESFO

Columbia Metropolitan

Fri 12/12

5:34 am-10:30 am

1 stop7h 56m

San Francisco

Sun 12/14

2:00 pm-11:31 pm

1 stop6h 31m

$309

ColumbiaSan Francisco

CAE - SFO

CAESFO

Columbia Metropolitan

Thu 1/29

7:30 pm-1:30 am

1 stop9h 00m

San Francisco

Sun 2/1

11:55 pm-2:14 pm

1 stop11h 19m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to San Francisco

What is the cheapest month to book a flight from South Carolina to San Francisco?

Currently, November is the cheapest month in which you can book a flight from South Carolina to San Francisco (average of $146). Flying from South Carolina to San Francisco in March is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SFO?

Find hourly flight availability from South Carolina to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2025.

A simple way to save on the total cost of your ticket is to fly from South Carolina to San Francisco in the afternoon. If you’re flexible enough to do this you can expect to save up to 7% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from South Carolina to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to San Francisco. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to San Francisco flight should consider departing on Tuesday mornings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from South Carolina to San Francisco

Explore weekly flight availability from South Carolina to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 5, 2025.

The most flights from USSC to SFO are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

Related info for your journey

Find useful and relevant information for your journey from South Carolina to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from South Carolina?

    Most people fly into San Francisco (SFO) if they book a flight to San Francisco from South Carolina. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

  • How long is the flight from South Carolina to San Francisco?

    Breeze Airways, Delta, and JetBlue can get you from South Carolina to San Francisco in just under 7h 31m. Your travel time can differ by up to 3h 48m. The distance between South Carolina and San Francisco is about 2389 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to San Francisco one-way?

    One-way options have recently been found by users for as low as $69 on Frontier. Other airlines that offer cheap prices include Breeze Airways from $92 and United Airlines from $180 one-way.

  • What are the most popular routes from South Carolina to San Francisco?

    The most popular route from South Carolina to San Francisco is Charlotte Douglas - San Francisco. You may also consider Charleston - San Francisco or Savannah/Hilton Head - San Francisco.

  • Can I find deals for flights from South Carolina to San Francisco that include hotel bookings?

    Yes. In addition to deals on South Carolina to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to San Francisco.

  • Can I find deals for business class flights from South Carolina to San Francisco?

    Yes. Cheapflights offers flight deals from South Carolina to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to San Francisco?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to San Francisco (average of $146). Flying from South Carolina to San Francisco in March is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Sunnyvale
Santa Clara
Vallejo
Hollister
San Bruno
Foster City
Redwood City
Union City
Burlingame
Lodi
San Mateo
Vacaville
Lathrop

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Top 5 airlines flying from South Carolina to San Francisco

Discover the top 5 airlines that operate flights from South Carolina to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$149Average$284FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$244Average$428FlexibilityNo cancel feeOn-time71%
DeltaCheapest$250Average$431FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$263Average$457FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$307Average$463FlexibilityNo cancel feeOn-time63%

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